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1. and all STARR Life Sciences Corp products are patent pending P N 115132 Rev 1 0 10 STARR Link2. Notes WARNING WARNING WARNING WARNING WARNING WARNING WARNING WARNING WARNING WARNING WARNING OPERATIONAL NOTE OPERATIONAL NOTE P N 115132 Rev 1 0 Replace unit if housing is broken or cracked DO NOT substitute the USB cable Use only parts that are packaged with the STARR Link device Investigational device only NOT for use on humans DO NOT place control box in an environment with oxygen fraction greater than 30 DO NOT immerse control box in liquids DO NOT short the ground and signal lines as this will permanently damage the internal electronics DO NOT directly expose control box to flammable or explosive gases DO NOT use STARR Life Sciences STARR Link USB cable with any other device Clean by wiping external surfaces of box and leads with light detergent and water Avoid spilling fluids on control box This STARR Link Analog Data Output Module should only be used with the MouseOx Plus Signal noise that exceeds 3 mV is likely due to the computer 3 STARA Link USER MANUAL 5 R Ral LIFE SCIENCES CORP 5 Using the STARR Link Module 5 1 Device Description The STARR Link Analog Data Output Module provides you with real time analog voltage outputs of your MouseOx Plus data The STARR Link can transmit up to 8 parameters at a 12 5 Hz update rate in 0 5 VDC range It connects to your computer with a USB cable A table in Section 5 4
3. details how to convert the voltage values to the units of the given physical parameter for each channel BNC Cable Connectors The STARR Link device is equipped with 8 BNC connectors Each connector is labeled with the output parameter assigned to that channel Power LED Indicator When lit the lower green LED indicates that appropriate power has been applied to the module via the USB cable If this indicator does not light there is no power going to the STARR Link USB LED Indicator When lit the upper green LED indicates that USB communications with the computer are ongoing This LED may blink while data are being transferred but it should not go completely dark 5 2 Output Parameters The STARR Link transmits analog outputs at an update rate of 12 5 Hz for the following parameters Oxygen Saturation S 02 Real time percent oxygen saturation of arterial hemoglobin The output analog voltage on this channel is proportional to oxygen saturation Heart Rate Real time cardiac pulse rate The output analog voltage on this channel is proportional to heart rate P N 115132 Rev 1 0 4 STARR Link USER MANUAL STARR LIFE SCIENCES CORP Pulse Distention A measurement of the distention of the arterial blood vessels residing between the sensors due to the cardiac output pulse Changes in its value are proportional to changes in local blood volume For given vascular resistance and compliance this parameter can be
4. of profits business interruption loss of information or any pecuniary loss even if SLS has been advised of the possibility of such damages Important Notice SLS products are designed to be used while under the supervision of research scientists in an experimental application All items sold by SLS are for NON HUMAN use The user is solely responsible in determining the suitability of any items from SLS for their particular use ALL SOFTWARE MANUALS COMMUNICATIONS ETC WILL BE IN THE ENGLISH LANGUAGE ONLY 9 Intellectual Property Notice 2005 2011 STARR Life Sciences Corp All rights reserved STARR Life Sciences the STARR Life Sciences logo and other STARR Life Sciences marks are owned by STARR Life Sciences and may be registered STARR Life Sciences the STARR Life Sciences logo and other STARR Life Sciences marks are owned by STARR Life Sciences Corporation may not be used without express written permission of STARR Life Sciences Corporation Technology Warning US and foreign patents are pending STARR Life Sciences Software is copyright protected The oximeter sensor measurement control unit and software are all protected by U S and international intellectual property laws Unauthorized reproduction or distribution of this oximeter system or certain portions of it will result in civil and criminal penalties and will be prosecuted to the fullest extent possible under the law The STARR Link
5. you are using although this should be discernable based on the magnitude of the numbers This channel will output Temperature unless a Multiplexer is detected by the MouseOx Plus system in which case it will provide Subject The output analog voltage on this channel is proportional to temperature in either unit Activity Activity is a binary valued parameter that indicates when the animal is moving versus sitting still It provides a value of 1 when the animal is moving and 0 when it is still It is provided as part of the MouseOx Plus Conscious Subjects Option and appears in place of the Pulse Distention parameter on the given STARR Link channel when you measure conscious subjects The output analog voltage on this channel is proportional to activity Subject Subject is the number of the animal active on the Multiplexer Note that Subject and Temperature are provided from the same channel The system will automatically replace the Temperature output with Subject when it detects the presence of a Multiplexer The output analog voltage on this channel must be converted to the numerical value of the Subject number active at the time data are being passed through the STARR Link P N 115132 Rev 1 0 6 STARR Link USER MANUAL 5 R Ral LIFE SCIENCES CORP 5 3 Operating Your STARR Link Before you begin to operate your STARR Link make sure that you have downloaded the latest Microsoft Windows
6. USER MANUAL 5 R Ral LIFE SCIENCES CORP Table of Contents 1 STARR LINK PACKAGED 1 2 DE VICE REQUIREMENTS 1 3 DEVICE SPECIFICATIONS sicsssssiccesesccececstacecssesscicecsvcsesesesseubesseacecssnssavisses 2 4 WARNINGS CAUTIONS AND OPERATIONAL 3 5 USING THE STARR LINK 4 5 1 DEVICE DESCRIPTION 0cceeccscceccesccsccecceccuccescesccecceccecesscsscsscscescesceess 4 5 2 QUTPUT PARAMETERS 4 5 3 OPERATING YOUR 5 0000000 7 5 4 VOLTAGE TO PARAMETER SCALE FACTORS csccscescecceccscescesceccecescesceces 8 6 CLEANING THE STARR LINK 8 7 CONTACTING TECHNICAL 8 2 2 1002 9 8 WARRANTIES AND 1 68 9 9 INTELLECTUAL PROPERTY 10 P N 115132 Rev 1 0 STARA Link USER MANUAL STAR Role LIFE SCIENCES CORP 1 STARR Link Packaged Parts The following is a list of parts that should be included in your STARR Link shipping box STARR Link Analog Data Out
7. cts must be received at STARR Life Sciences Corp 333 Allegheny Ave Suite 300 Oakmont PA 15139 no more than thirteen 13 months from the original date of shipment by SLS All shipments must include a Return Authorization Number RMA obtainable from SLS and must be sent freight prepaid by the sender This warranty is nontransferable This warranty does not apply to any defects or damages caused by an animal or resulting from alteration modification neglect misuse usage of an improper power sources damage in transportation abuse or any cause other than normal use of the Non disposable Products This warranty does not apply to products resold by SLS that are manufactured by other companies No warranty or claim is made by SLS regarding the efficacy of any product for any particular application Except for the Limited Warranty expressly set forth above SLS MAKES NO WARRANTIES WHATSOEVER SLS HEREBY DISCLAIMS ALL WARRANTIES EXPRESS OR IMPLIED ORAL OR WRITTEN INCLUDING WITHOUT LIMITATION ANY IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY IMPLIED WARRANTIES ARISING FROM ANY COURSE OF DEALING USAGE OR TRADE PRACTICE P N 115132 Rev 1 0 9 STARR Link USER MANUAL 5 R Rade LIFE SCIENCES CORP In no event shall SLS be liable for any damages whatsoever arising out of the use of its product including without limitation any direct incidental or consequential damages any damages for loss
8. eath Rate 4 est 5 05 7 Good Good Good Good 6 LostSignal Unsure Unsure Unsure Unsure Unsure 8 Breathing Artifact Unsure Unsure Unsure Unsure Unsure 9 Signal Optimization Unsure Unsure Unsure Unsure Unsure In this table each of the error codes is defined for the physiological parameters listed on the right hand side For a given error code the parameter at P N 115132 Rev 1 0 5 STARR Link LIFE SCIENCES CORP USER MANUAL 5 R Ral that location will be either Good or Unsure Good means that the given measurement satisfies all of our acceptance criteria Unsure means that the given measurement does not meet our acceptance criteria during the presence of that particular code Breath Distention A measurement of the distention of the arterial blood vessels residing between the sensors due to changes in intra thoracic pressure associated with breathing Changes in its value are proportional to changes in local blood volume Breath Distention can be correlated with breathing effort or specifically intra thoracic pressure The output analog voltage on this channel is proportional to breath distention Temperature Real time measurement of Rectal Temperature when you purchase the MouseOx Plus Body Temperature Option Temperature can be output in either C or F and the conversion factor is the same for both unit Thus you must record what units
9. hat channel All voltages are scaled values of the actual parameters as measured by the MouseOx Plus The actual values of the parameters can be back calculated from the analog voltages using simple proportional scale factors individual for each channel Other specifications are given below Device Compatibility This STARR Link can be used with the STARR Life Sciences MouseOx Plus Channel Configuration The STARR Link provides output for 8 channels of data These are Oxygen Saturation File Marker Heart Rate Error Code Breath Rate Breath Distention Pulse Distention or Activity Temperature or Mouse When measuring Conscious Subjects Activity replaces Pulse Distention When using a Multiplexer Mouse replaces Temperature Output The STARR Link transmits analog voltage representations of digital data a range of 0 to 5 VDC updated at a rate of 12 5 Hz When using the MouseOx Plus signal updates are delayed by 0 7 seconds from real time due to the method by which data are collected and the parameters are calculated However no delay is added by the STARR Link and the current value delivered from the MouseOx Plus will be immediately sent out on each channel at a 12 5 Hz or 80 msec update rate Accuracy Accuracy of STARR Link analog outputs from each channel is 3 mV P N 115132 Rev 1 0 2 STARR Link USER MANUAL STAR Rah 4 Warnings Cautions and Operational
10. oncern Calibration of the STARR Link Your STARR Link was calibrated at the factory and will be fully calibrated when you receive it Calibration constants are contained in the FLASH memory of the device If a change in calibration is suspected please contact STARR Life Sciences customer service at 1 866 978 2779 or by e mail at support starrlifesciences com Connecting to the Recording Device The channel connectors on the STARR Link are 50 Q BNC type Connections to your recording device can be made with any standard BNC cables You can also use any number of conversion jacks that allow you to P N 115132 Rev 1 0 7 STARR Link USER MANUAL STAR Role LIFE SCIENCES CORP l switch to another connection standard e g banana jacks but it is imperative that the voltage outputs not be shorted for gt 100 ms Shorting the voltage outputs can permanently damage the control board in the STARR Link control box If for some reason you use multiple recording devices simultaneously make sure that the devices have a common ground This can be achieved by using devices that receive AC power from a plug that has an active earth grounding pin If you suspect that the ground on a device might be floating make a direct connection between that device and your other measurement devices before connecting cables to the STARR Link 5 4 Voltage to Parameter Scale Factors All of the STARR Link parameters are transmitted as
11. proportional to blood pressure This channel will output Pulse Distention unless you are operating the MouseOx Plus system using Conscious Subjects software in which case it will output Activity The output analog voltage on this channel is proportional to pulse distention Respiratory Rate Breath rate updated every few seconds Note that this parameter is actually derived from respiratory effort and will be present even if the animal is experiencing an obstructive apnea as long as breathing effort is present The output analog voltage on this channel is proportional to breath rate File Marker File markers are user selected flags available in the MouseOx data collection system that indicate the location of up to 50 significant events per data set It is up to the user to make note of the significance of each marker The marker numbers start at 0 and proceed sequentially with each entry by the user The STARR Link provides an analog voltage on this channel that is proportional to the most recent file marker integer Error Code Error codes are given in the table just below More detail on their significance is provided in the MouseOx Plus User Manual The output analog voltage on this channel must be converted to the error code listed in the table Error Error Desertai 0 Heart Breath Pulse Breath Codes Rate Rate Distention Distention 0 NoBror Good Good Good Good 2 Lost Pulse 3 Lost Br
12. put Module Control Box 2 meter STARR Link USB Cable STARR Link User Manual Please check to see that you have all of these parts before proceeding to installation If you find any part missing please contact STARR Life Sciences at 1 866 978 2779 or by e mail at support starrlifesciences com 2 Device Requirements The STARR Link has the following use and interface requirements Hardware You must have a functioning STARR Life Sciences MouseOx Plus device Software The STARR Link does not require special software since all drivers and controllers are contained within the MouseOx Plus software Computer Hardware Your computer must have at least one 2 0 USB port to accommodate the STARR Link Electrical Requirements Your external recording device must have high impedance inputs P N 115132 Rev 1 0 1 STARR Link USER MANUAL 5 R Ral LIFE SCIENCES CORP 3 Device Specifications The STARR Link provides analog outputs of 8 channels and 10 parameters of data obtained from the STARR Life Sciences MouseOx Plus The STARR Link allows you to electronically record those parameters to your own recording device The outputs provide analog voltages in a 0 5 VDC range but they are not true analog voltages They are real time analog voltages proportional to digital data calculated by the measuring device and they update at a 12 5 Hz rate Each channel provides a specific parameter only for t
13. updates For first time operation please do the following in the order given Also make sure that you have loaded the latest software for your MouseOx Plus Connecting the USB Cable Connect the USB cable to your STARR Link control box then to the computer Note that power to your STARR Link is provided through the USB cable When you first connect the USB cable you should see the lower LED on the STARR Link control box illuminate The first time that you connect the USB cable a popup balloon or dialog box will appear that says Found New Hardware to identify the presence of the newly detected control board residing within the STARR Link You must wait until your computer indicates that the drivers have been installed at which point another balloon or dialog box will appear saying Your new hardware is installed and ready to use When using the STARR Link the USB LED Indicator will light whenever data are being transferred If the light shuts off during data transfer you have lost communication with the computer To re establish communication simply disconnect the USB cable from the computer then reconnect it Be sure to wait about 10 seconds after both actions before continuing This should restore communication with the computer and the USB LED Indicator should be lit again Note that during operation the USB LED Indicator will blink while data are being transferred This is normal and is not a cause for c
14. voltages within the range 0 5 VDC To convert back to the actual value of the parameter use the conversion factors given in the following table To Convert Voltage to Correct Units after Parameter Units see right column Multiply Conversi n Parameter Voltage by 360 6 Cleaning the STARR Link The STARR Link device and all accompanying cables should be cleaned using only light detergent and water P N 115132 Rev 1 0 8 STARR Link USER MANUAL STAR Ral LIFE SCIENCES CORP 7 Contacting Technical Support STARR Life Sciences values its customers and is dedicated to providing quality products and solutions to meet your needs For technical support please call or email STARR Life Sciences at 1 866 978 2779 or support starrlifesciences com 8 Warranties and Liabilities Limited Warranty amp Disclaimer STARR Link SLS warrants its non disposable hardware and sensors the Non disposable Products against defects in material workmanship and performance for a period of one 1 year from the date of shipment by SLS the Warranty Period SLS warrants that the Non disposable Products will meet the electronic and mechanical specifications stated in the SLS user manual although the specifications are subject to change without notice SLS at its option will repair or replace a Non disposable Product that is found to be defective during the Warranty Period Defective Non disposable Produ
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