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Milli-Q Synthesis and Milli

1. 8 don PEE 8 When do change the UV lamp ied 8 CUL P 8 What are the different types of Quantum Cartridges 8 2 2 12 2 2 02 02022 2 1 12110000001 8 When do change the Quantum Ultrapure Cartridge 22 22 22 2 25 5 2 222222 2022 22222220202 8 DOO UF ETE PK 9 Resistivity and temperature MEASUreMEN S 9 Temperature Compensation Conductivity 22 2202 222 5 000 222222202222200 9 Resistivity temperature measurements in agreement with USP 24 4 4 44 12 9 TABLE CONTENTS e OJO ARRA F F TTrTT FTTT TFTETTKTTTFKKTTT T TE vili ie ERE FF FF 10 What types of MilliPak Filters are there 2 2 1 2 2 2 1 2 111000000000000 EEE EE bbe 10 VSO change SV O 12 aee ee a ca LO ke 12 Whai mainienance is inyoked wiii ihe A lO P
2. GS NE 12 Does the ATO need to be calibrated 2 12 S exc 12 2 4 TECHNICAL SPECIFICATIONS 0 2 2717 13 Dimensions ylen and COIN EN 18 2 EE 13 rec I3 Measurement Ranges for TOC Resistivity Conductivity and Temperature 18 opro ccs 4 DIT M 14 3 FRE INSTALLATION 15 eu Sz o ITT e SEG re TRECE Lo SEED SIMIETO a ma nn ma ce ener ars me pe a pe p kes pene 16 reel TTT 17 Wall Mounting 22 2 12 22 2 02 1202202222202 02222222222 022 202022111221 17 Pressure 6070 2 Ball Valve for shutting off feedwater supply 17 Remote Point Of Use Dispenser MEME 17 Remote Point Of Use Dispenser used a Production 18 qoc c RITR E E 18 Pinter or Gon ge 18 Remote Display with Keypad 18 yovv
3. 27 279 OF THE 27 i ik 2 30 4 5 INSTALLATION OF THE QUANTUM CARTRIDGE 30 Ay rote siz ON 30 PURGING THE FROMTHE SYSTEM DA 6 22 4 8 HYDRATING THE SYSTEM isses II nee n e e e e e e e e e e a e sen cens 32 AND RINGING OF THE MIPAK 2 a 10 HOW TO CALIBRATE THE FIOWRATEFROM THE IVI E 35 4 11 HOW TO CHANGE THE DISPLAYED 741 38 4 12 HOW TO SHOW EITHER MO CM OR US CM RESISTIVITY OR CONDUCTIVITY UNITS 39 4 13 HOW TO SHOW NON TEMPERATURE COMPENSATED RESISTIVITY OR CONDUCTIVITY VALUES 41 Al Why use non temperature compensated values 9 4 JHE TIME COE DAY dane kd sao dao RO Soter EEE 44
4. 5 46 TROM THE MU ca 46 5 2 STANDBY PRE OPERATE AND PRODUCT MODE A8 What is STANDBY mode 8 A8 MTs REO BRA TROIS teres A8 Viet 1S PRODUCT mode MERERI 48 5 3 HOW TO VIEW THE RESISTIVITY TEMPERATURE AND QC 49 et ee ee eee ____ _____ _ _ _ _ _ _ _ _ eer ee eee 49 Wc eB ____ ___ 6_6_ _ _ 6 _8 49 MIO us oats at EE _______ _____ 49 5 4 HOW TO USE THE FOOTSWITCH OPTIONAL 55 I m meme eee 50 HOV CEN TE A IS UN 50 5 6 HOW TO VIEW THE AGE OF THE CONSUMABLES 52 or HOW TO UNDERSTAND 54 TABLE CONTENTS CHAPTER 6 MAINTENANCE ee ees 57 6 1 PAINTER NORO o RR OE NEER EE HOWTO REPIAGE THE nn o Go HOVFTOREACE TEESUANTUN ATRIDO E mdo tea amo 59
5. Follow the instructions below for cleaning the Screen Filter Make sure Milli Q is in PRE OPERATE mode locate the Shut Off Valve on the feedwater supply Turn off the valve Bring the POU Dispenser Trigger forward for about 5 seconds The Milli Q will go into PRODUCT mode This will depressurise the Feedwater Tubing Bring the POU Dispenser Trigger back Q Place the Milli Q into STANDBY mode locate the Screen Filter This will be located where the feedwater 8 mm tubing originates i e where the 8 mm tubing meets a pressurised pipe Q Unscrew the collar that holds the Feedwater Tubing to the barbed end of the fittings Pull the tubing off of the fitting Unscrew the Screen Filter from the Feedwater Pipe Loop Go to a sink and flush tap water backwards through the Screen Filter The water would flow through the barbed end first Any trapped debris on the Screen Filter would be flushed out Stop flushing the Screen Filter View inside to make sure it is now clear of debris locate the Roll of Teflon Tape from the Milli Q Accessories Bag from the Shipping Apply 3 4 turns of new Teflon Tape to the threads of the Feedwater Pipe Apply the tape in a clockwise direction Screw the Screen Filter back onto the Feedwater Supply Pipe Attach the Feedwater Tubing back onto the Barbed Fitting Make sure the tubing is securely fastened Open the Feedwater Supply Valve Place the
6. SANITISING AND CLEANING THE UF CARTRIDGE Place the Milli Q into STANDBY mode See Section 5 1 if you need further instructions on how to do this click will be heard and water will flow for a few seconds out of the UF Reject tubing While in STANDBY mode move the POU Dispenser Trigger forward This will open the electric valve inside the POU Dispenser Any residual water pressure will be released Allow any water to flow from the POU Dispenser in STANDBY mode Move the POU Dispenser Trigger back to the upright position Locate the Removal Tool from the Accessories Bag Locate the Sanitisation Port Cap on the top of the Milli Q system It is located towards the back top end of the system cabinet Unscrew the cap using the Sanitisation Port Removal Tool found in the Accessories Bag Place 3 grams of Sodium Hydroxide crystals pellets in the Sanitisation Port Screw the cap back Do not use the Removal Tool to tighten the Sanitisation Port Cap It may overtighten it There are 2 rubber O rings which provide a seal to prevent water leakage Handtighten the cap until it will not turn any further lf the cap is overtightened then it may become very difficult to remove it later for the next Sanitisation lf the cap is not tight enough then there may be a leakage of caustic NaOH solution out of the Sanitisation Port 66 MAINTENANCE Make sure the Sanitisation Port Cap is tightened after putting in the AN HAZARD Sodium Hy
7. Leave the Milli Q in PRE OPERATE mode 3a INSTALLATION INSTALLATION OF BARBED FITTING AND TYGON TUBING PURGING AIR FROM THE QUANTUM CARTRIDGE INSTALLATION AND AIR PURGE OF THE MILLIPAK 34 INSTALLATION 4 9 INSTALLATION AND RINSING OF THE MILLIPAK Obtain MilliPak Remove the Tygon Tubing and the Barbed Fitting from the POU Dispenser Q Screw the MilliPak onto the POU Dispenser Do not use any Teflon Tape on the threads of the MilliPak The MilliPak should be turned until it is handtight Do not overtighten the MilliPak Do not use Teflon Tape on the threads of the MilliPak The POU A ATTENTION Dispenser has an O ring inside which provides a watertight seal Move the POU Dispenser Trigger forwards This will bring the Milli Q system into PRODUCT mode Locate air vent valve top side clear side of the MilliPak Open this slowly but do not remove it from the MilliPak Allow any air on the clear side of the MilliPak to be vented out Q Dispense about 5 litres of water Make sure all air is purged out Air will not pass through the membrane filter in the MilliPak lf there A ATTENTION is trapped air in the MilliPak then a reduction in Product Water flowrate can result Move the POU Dispenser Trigger back to the upright position The Milli Q should now be in PRE OPERATE mode 90 seconds later Leave the Milli Q in PRE OPERATE mode It is highly recommended not to put Tygon
8. 0 3 bar then turn the round handle on the Pressure Regulator clockwise until the pressure gauge on the regulator shows 0 3 bar Check this again when water is tlowing through the Pressure Regulator setting of the Pressure Requlator should not exceed 0 3 bar feedwater pressure reaching the Milli Q PRODUCT mode should not exceed 0 3 bar The Pressure Regulator should only be set while water is flowing through it It is perfectly normal to see an increase in the Pressure Regulator setting while water is not flowing through it i e STANDBY or PRE OPERATE mode The Milli Q will now go to STANDBY mode and will remind you to close the POU Dispenser Valve Move the POU Dispenser Trigger back its upright position The Milli Q will now go to PRE OPERATE mode STANDBY PRE OPERATE CLOSE THE VALVE Milli Q Synthesis ATO only When you Close Valve the Milli Q will go to PRE OPERATE mode and then will start an automatic 60 minute A10 CLEANING The ATO CLEANING is a way of flushing out any particles that may have been present STANDBY PRE OPERATE CLOSE THE VALVE A10 CLEANING 60 Milli Q Synthesis A10 only Allow the ATO CLEANING to count down to minutes The remaining steps of this section apply to both the Milli Q Synthesis and the Milli Q Synthesis ATO Any remaining air in Quantum Cartridge can be hand purged out now Q Geta screwdriver with a very thi
9. 22 2 2222 212 22 2 020222 02022222 202022222 202222222222222220 o The problem is there is no power to the Milli Q 2 6 7 79 The problem is there is an ERROR Number Alarm displayed 79 Continuation of ERROR Number Alarm displayed eene enne nennen 80 The problem is a message is displayed with a Flashing Service or Alarm 81 P CET 82 8 ORDERING 15 146 11 1 4 83 8 SSE SARIO BER 19 i 83 8 2 CATALOGUE NUMBERS FOR ACCESSORIES 222222222222 rete rer aca rk ca e Dr 84 NUMBER 84 9 APPENDIXES r 85 ccm 85 APPENDIX 2 HOW TO TRANSFER INFORMATION TO A PRINTER 922 O TABLE CONTENTS Requirements needed 87 Mr 8 MINES SS TE 88 APPENDIX SEIOVWCTOC BSANISEER INIGORAAATION TOC COMPUTERS 25
10. It is possible to download data from Milli Q to a computer The data can be graphed and presented on the computer example of this would be to display the resistivity of the Milli Q Product Water for the last 20 days Millipore sells as an accessory not supplied with the Milli Q software that can used to download data from the Milli Q This software can then be used to process the data in different ways The Millipore Catalogue Number for the Explore Data Software is SOFTOOOAT You will also need a computer cable to be used between the Milli Q and a computer This cable is not supplied with the software or with the Milli Q The Millipore Catalogue Number for this cable is COMPCBLOT See Section above labelled Printer or Computer Cable for more information PRE INSTALLATION FOOTSWITCH WALL MOUNTING BRACKET BALL VALVE PRESSURE REGULATOR REMOTE DISPLAY REMOTE POU DISPENSER MILUPORE Milli Q Synthesis Synthesis 19 PRE INSTALLATION 3 4 INSTALLATION REQUIREMENTS CONSUMABLES NEEDED FOR INSTALLATION You will need one Q Gard Pack Quantum Cartridge and MilliPak for installation These items do not come with the Milli Q system These items need to be ordered separately The Catalogue Numbers and options for these items are written below Some of the items below can be ordered as part of a kit An example might be a kit consisting of a particular type of Quantum Cartridge plus a MilliPak
11. The Remote Display is an accessory that allows you to have the LCD and Keypad and LEDs located up to 2 4 meters away trom the Milli Q System The Millipore Catalogue Number for the Remote Display is ZMQSRMDS1 The Remote Display Installation Instructions are not included with this Owner s Manual These Installation Instructions are included with the Remote Display Please contact Millipore if you would like a copy of these instructions ahead of time All of the instructions given in this manual will work with the Remote Display For example suppose you wanted to use the Volumetric Dispenser Function of the Milli Q See Section 5 5 The use of the Keypad is exactly the same when using the Remote Display APPENDIX 5 HOWTO USE A REMOTE POU DISPENSER The Remote POU Dispenser is an accessory that allows you to dispense Milli Q Product Water up to 2 5 meters away the Milli Q system The Remote POU Dispenser uses the same POU Device found on the front of the Milli Q Remote POU Dispenser Arm is fixed to a Base The Base can be wall mounted or the Base be fitted with a metal weight for placement on a table or countertop The Millipore Catalogue Number for a Remote POU Dispenser is ZMQSPOUR1 It is also necessary to have an Installation Kit for the Remote POU Dispenser This kit allows an interface between the Remote POU Dispenser and the Milli Q Millipore Catalogue Number for the Remote POU Dispenser Installation Kit i
12. 15 C Note that 25 C is missing in non temperature compensated display mode You have finished changing to non temperature compensated Resistivity or non temperature compensated Conductivity Displays A3 INSTALLATION 4 14 HOWTO SET THE DATE AND THE TIME OF DAY The date day month year can be printed out or downloaded to a computer along with other operating data pertinent to the Milli Q The date is changed at midnight of each day The time of day is not printed out or downloaded to a computer it is used only to advance the date Follow the steps below to change the Date or the Time Of Day Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 CLEANING Press MENU for about 2 seconds You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the CD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button about 2 seconds This will place the Milli Q into STANDBY mode Then press the STANDBY OPERATE Keypad Button again The Milli Q will now be in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Service Software Press the MENU Keypad Button 7 times 8 times for a Milli Q Synthesis Stop when you see the CALENDAR display PRESET VOLUME T a AGE ji SERVICE
13. 18 3 4 INSTALATION 6 2 20 Consumables needed for cele EE 20 Space CMG WAIN KOJOT INTS ee EE E EEEE A R 20 EE EEEE EAEE ee coc Ge dete ad ete cine cece EE TE ace ees 20 Feedwater Kequirements 21 genu 21 21 33 WNPACKING THE BOX VV AAT S INSIDE au asno seson nd E Ea E e via 22 TABLE CONTENTS CHAPTER 4 INSTALLATION gt 24 4 CONNECTING TO A SUPPLY OF FEEDWATER 2 0 0000000000000 24 Feedwater is HOM a 656 7 0 24 Feedwater is from pressurised source such as a pipe a loop 24 4 2 CONNECTION OF TUBING AND THE 0 26 Feed water 5 202 26 Feedwater Pressure Relief Tubing 26 eapo Pe NNMERO 26
14. Q Bring the POU Dispenser Trigger down The AIR PURGE will begin A sharp click will be heard This is the opening of a UF Cartridge Reject Solenoid Valve Water will begin to flow through the UF Cartridge Reject tubing The AIR PURGE will last for 5 minutes When the timer reaches minutes the Milli Q will go into STANDBY mode The LCD will prompt you to CLOSE THE VALVE SERVICE UF STANDBY AIR PURGE 0 mn CLOSE THE VALVE a Close The Valve by bringing the POU Dispenser Trigger back to the upright position The Milli Q will now go to PRE OPERATE mode STANDBY PRE OPERATE CLOSE THE VALVE You have finished performing an AIR PURGE 6 12 HOW TO REPLACE THE UV LAMP The UV Lamp is normally replaced once a year every 365 Days A message EXCHANGE UV will appear after 365 Calendar Days indicating that the UV Lamp needs to be replaced It is recommended to have a Millipore Field Service Representative change the UV Lamp replacement of the UV Lamp involves removing the cover of the system instructions for replacing the UV Lamp are not included in this manual The instructions are included with the replacement UV Lamp Contact Millipore for a copy of these instructions if you would like to see them before ordering a replacement UV Lamp TROUBLESHOOTING Chapter 7 TROUBLESHOOTING THE PROBLEM IS LOW OR NO FLOWRATE FROM THE POU DISPENSER CAUSE REMEDY System is in PRE OPERATE mode
15. CALIB l FLOW MEASURE Press MENU SERVICE OPTIONS each time CALENDAR 09 07 WED AUG 1 01 The Hour will be flashing Hour is flashing CALENDAR 09 07 WED AUG 1701 44 INSTALLATION Q Change the Hour by using the MEASURE or CLEANING Keypad Buttons CALENDAR 09 07 WED AUG 1 01 CALENDAR 10 07 WED AUG 1 01 increase the Hour Press the OPERATE Keypad Button to validate select the Hour The Minutes will now be flashing CALENDAR 10 07 WED AUG 1 01 Minutes flashing Repeat the two steps above to change the Day Of Week the Month the Day and the Year When you are finished press MENU for more than 2 seconds to go back to PRE OPERATE mode PRE OPERATE CALENDAR 10 07 WED AUG 1 01 You have finished setting the Date and the Time Of Day 45 USING THE MiLLI Q Chapter 5 USING THE MiLLI Q 5 HOW GET WATER FROM THE MILLI Q These instructions are written for the Milli Q user who already has completed all of the installation steps in Chapter 4 l Make sure the Milli Q is in PRE OPERATE mode the Milli Q is in STANDBY mode then press the OPERATE STANIDBY Keypad Button for about 2 seconds This will change the Milli Q from STANDBY mode to PRE OPERATE mode See the drawing below for more information STANDBY is shown below PRE OPERATE on Milli Q systems with an 10 CLEANING Press for about 2 seconds Mov
16. ERROR 4 The water entering the is lt 4 C Contact Millipore You may continue to use the Milli Q A10 ERROR 5 The water entering the is gt 41 C Contact Millipore You may continue to use the Milli Q A10 ERROR 6 The conductivity of the water entering the ATO is gt 1 1 uS cm Contact Millipore You may continue to use the Milli Q A10 ERROR 7 The temperature inside the ATO during its analysis mode reached gt 55 C Contact Millipore You may continue to use the Milli Q A10 ERROR 9 The TOC is very low or a problem occured with the ATO Contact Millipore You may continue to use the Milli Q 80 TROUBLESHOOTING THE PROBLEM IS A MESSAGE IS DISPLAYED WITH A FLASHING SERVICE OR ALARM LED LCD MESSAGE DISPLAYED REMEDY EXCH CARTRIDGES e The Q Gard Pack and Quantum Cartridge have as been installed for 180 Calendar Days or the The Milli Q can still be used if the water quality Resistivity is lt 16 the Resistivity Setpoint resistivity and values is within specifications Replace the Q Gard Pack and Quantum Cartridge Check the value of the Calendar Day timer and the Resistivity Setpoint Contact Millipore to do this START SANIT e Perform a Sanitisation of the UF Cartridge See Section 6 5 for information on how to do this The Milli Q can still be used TOC gt SETPOINT e The displayed TOC value is greater than the TOC Setpoint Conta
17. Express 20 See Chapter 8 Section 8 1 for the catalogue numbers and descriptions of various kits See Section 2 3 for technical information regarding the Consumables for a Milli Q system Q Gard Purification Pack gt Q Gard 1 QGARDOOR 1 1 box RO Elix distilled Milli RX Milli RO feedwater Q Gard 2 QGARDOOD2 1 box DI Service DI feedwater Quantum Ultrapure Cartridge gt Quantum QTUMOOOIX 1 1003 lon Exchange Resin gt Quantum EX QTUMOOOEX 1 box Exchange Resin media tor Organics removal Quantum VX QTUMOOOVX 1 box Volatile Organics removal ion exchange resin Quantum Ultrapure Cartridge with 1 non sterile MilliPak 20 Express Quantum IX QTUMMPEIX 1 box gt Quantum QTUMMPEEX 1 box MilliPak 40 Final Filter MilliPak 40 sterile MPGLO4SK2 2 box MilliPak Express 20 Final Filter MilliPak Express 20 non sterile MPGPO2001 1 box SPACE AND WEIGHT REQUIREMENTS See Section 2 4 for a drawing showing the dimensions of a Milli Q Total Height needed includes POU Dispenser being fully upright 53 cm Total Width needed includes room needed to remove 45 cm Total Depth needed includes POU when it is fully upright 53 Operating weight for a wet Milli Q Synthesis Synthesis 16 kg 16 8 kg ELECTRICAL REQUIREMENTS he electrical requirements for a Milli Q Synthesis or Milli Q Synthesis are 120 VAC 10 50 60 Hz 0 5 amp
18. File Capture to Printer Make sure the Milli Q is in PRODUCT mode It is not possible to download to a computer while the Milli Q is in PRE OPERATE or STANDBY mode Q Press the MENU Keypad Button for about 2 seconds The LCD will change as shown here PRESET VOLUME Cc 0 00 18 2MQ cm 25 C TOC 4 ppb CLEANING Press MENU for about 2 seconds 90 APPENDIXES Q Press the MENU Keypad Button one more time The LCD will change as shown here SERVICE PRINTER quel PRESS MEASURE Press MENU Press the MEASURE Keypad Button Information will be sent to the Computer The Milli Q will return to PRODUCT mode automatically SERVICE PRINTER PRESS MEASURE CLEANING 18 2MQ cm 25 C EB oc 4 ppb 0 Press MEASURE When the data transfer is complete open the TRANSFER menu and then click on CAPTURE TEXT STOP To transfer this data into an EXCEL file 1 Open Microsoft EXCEL Open the file you downloaded it will have a txt file extension 2 Choose DELIMITED for the FILE TYPE of your data Press NEXT TAB is the Delimiter 3 Press NEXT and then FINISH 4 Save the new file as a Microsoft Excel Workbook if you want to graph the data or do any calculations with the data You may also purchase the EXPLORE DATA Software from Millipore Contact Millipore for further details of this accessory APPENDIXES APPENDIX 4 HOWTO USE A REMOTE DISPLAY
19. MAY NEED WALL MOUNTING BRACKET The Millipore Catalogue Number for the Wall Mounting Bracket is SYSTFIXO1 The mounting hardware for attaching the bracket to a wall is not included and must be supplied The bracket is attached with at least 2 bolts screws Width of bracket 2 23 cm Height of bracket 2 5 4 cm Thickness of bracket 0 4 cm Diameter of holes in the bracket for bolts or screws 2 O 7 cm Mounting holes on bracket are approximately 5 4 cm from either edge PRESSURE REGULATOR The Millipore Catalogue Number for a Pressure Regulator with Pressure Gauge and 8 mm tubing connections is ZFMQOOOPR It is important that the Pressure Regulator is adjusted while water is flowing through it A range between 0 1 bar and 0 3 bar 1 5 to 4 5 psi is the normal setting of the Pressure Requlator while water is being dispensed from the Milli Q Pressure Regulator is factory pre set to 0 3 bar while water at 80 LPH is flowing through 11 BALL VALVE FOR SHUTTING OFF THE FEEDWATER SUPPLY It is highly recommended to use ball valve on Feedwater Tubing The Ball Valve will be used to shut off the Feedwater Supply if necessary Contact Millipore for information regarding the Ball Valve lt is usually necessary to have fittings installed on both ends of the Ball Valve to be able to connect it to the Feedwater Tubing REMOTE POINT OF USE DISPENSER A Remote POU Dispenser can be added to the Milli Q This allows you
20. Milli Q into PRODUCT mode to dispense some water from it See Section 5 1 for more information on how to do this During this time check the setting of Feedwater Pressure Regulator It should be set to a value between O 1 bar and 0 3 bar leave the Milli Q in PRE OPERATE mode when you are done dispensing water You have finished cleaning the Screen Filter 0 MAINTENANCE SCREEN FILTER CLEANING TIGHTENING OF THE POU DISPENSER ARM Milli Q Synthesis Synthesis MAINTENANCE 6 7 HOW TO TIGHTEN THE POU DISPENSER ARM The POU Dispenser Arm is moved up and down during the times that water is dispensed from the Milli Q System Follow these instructions to tighten the POU Dispenser Arm locate the Allen Wrench 6 sided black wrench trom the Accessories Bag from the Shipping Q locate the 2 bolts that hold the various pieces of the Dispenser Arm in place Tighten these bolts until the arm is secure You have finished tightening the POU Dispenser Arm 6 8 How TO REPLACE THE ATO UV LAMP The A10 UV Lamp is normally replaced once a year every 365 Days A message EXCHANGE ATO UV will appear after 365 Calendar Days indicating that the ATO UV Lamp needs to be replaced It is recommended to have a Millipore Field Service Representative change the ATO UV Lamp replacement of the ATO UV lamp involves removing the cover of the system The instructions for replacing the ATO UV Lamp are not
21. Milli Q will not operate This message must be resolved before the Milli Q can operate NO FEED WATER The Milli Q will not operate This message must be resolved before the Milli Q can operate Milli Q Synthesis The Q Gard and Quantum have been installed for more than 180 Calendar Days A sanitisation of the UF Cartridge should be pertormed This message appears because of a timer This message normally appears 4 weeks after the previous UF Cartridge Sanitisation The age of the UF Cartridge is greater than the UF Cartridge timer established in the software The displayed TOC Milli Q Synthesis only is greater than the TOC Setpoint established in the software Either Q Gard Pack or the Quantum Cartridge is not installed correctly or one of them is absent An optional accessory has detected that there is no feedwater going to the Milli Q This accessory is not factory installed and needs to be installed in the system What to do Replace the Q Gard and the Quantum and the MilliPak Perform Sanitisation of the UF Cartridge See the Maintenance Chapter of this Manual See Chapter 6 Section 6 5 for information on how to do this Contact Millipore to replace the UF Cartridge A TOC value above the TOC Setpoint can have many causes Contact Millipore Reinstall either or both the Q Gard Pack or the Quantum Cartridge Make sure the Reservoir or the Pressurised Pipe feeding the Mill
22. OA HOW TO REPIACE THE pd ke rn l 64 OO AON TOSANITISEAND CIEAN THE UP CARTRIDGE asus reote RP eere aber How often would normally Sanitise and Clean UF Cartridge 66 Things to know BEFORE you sanitise the UF 70056 66 and Cleaning UF 66 Oe med zz Er Mz ee ees ete 0 5713720065 7 oc abso 2 OD THOU TOSIBAN THEA TOC BAONITORING DEVICE 72 72 EU UNE 72 ef ene TART 72 mer 11918 e NR REN AEEA EAEE 73 Flow de cancel ne ATO CLEANING One if IS SUOJN 74 OLO OV aae CI CIN IDE 4 PUT TOW CP NN 7 TRGUELESHOOTING 77 The problem is low or No Flowrate trom POU 7 5 6 756 The problem is low Resistivity of the Product
23. PCB A D converter defective 10 Thermistor defective Problem occured with compensation temperature The water entering the ATO is 4 C The water the 10 is wu eC entering The conductivity of the water entering the is gt 1 1 uS cm The temperature inside the during its analysis mode reached gt 55 C TOC is very low or a problem occured with the 10 USING THE MiLLI Q What to do Contact Millipore Turn off the Milli Q Turn it back on about 20 to 30 seconds later If the message continues then contact Millipore Turn off on the Milli Q and dispense water for gt 6 minutes If the message continues contact Millipore Turn off on the Milli Q and dispense water for gt 6 minutes If the message continues contact Millipore Turn off on the Milli Q and dispense water for gt 6 minutes If the message continues contact Millipore Turn off on the Milli Q and dispense water for gt 6 minutes If the message continues contact Millipore Contact Millipore Contact Millipore Contact Millipore Contact Millipore Contact Millipore 56 MAINTENANCE Chapter 6 MAINTENANCE 6 1 MAINTENANCE SCHEDULE See the Maintenance Guide below for the typical maintenance that needs to be performed on your Milli Q Synthesis or Milli Q Synthesis ATO The Catalogue Numbers and other ordering information can be found in Sections 8 1 and 8 2 Detailed information
24. Place Milli Q into PRODUCT mode See Section 5 1 No feedwater to the Milli Q from the Reservoir Reservoir is Remove the Feedwater Tubing from the Milli Q Fitting on bottom of Reservoir is too tight gasket on Contirm that there is water coming to the Milli Q fitting is flattened and restricts water flow Reservoir is located lower than the Milli Q Kink in Feedwater Tubing Valve on bottom of Reservoir is closed by mistake No feedwater to the Milli Q from Pressurised Pipe No water in Loop Loop Remove the Feedwater Tubing from the Milli Q Water is not pressurised in Loop Contirm there is water coming 19 the Milli Q Pressure Regulator on Feedwater Tubing is not adjusted to between and 0 3 bar while water is flowing through it Milli Q in PRODUCT mode See Section 4 7 e Pressure Regulator is installed backwards See Section 4 1 MilliPak is airlocked e Vent air out while system is in PRODUCT mode See Section 4 9 MilliPak is clogged and will not allow water through it e Measure water flow with and without MilliPak installed Change MilliPak and vent air out See Section 4 9 Screen Filter Clogged e Clean the Screen Filter See Section 6 6 Problem with internal component motor not operating Contact Millipore Inlet Solenoid Valve not opening etc Remote POU Dispenser connected wrong or not e Check tubing connections on back of Milli Q See plugged into the Milli Q instructions that came w
25. TO READ THESE INSTRUCTIONS BEFORE USING THIS EQUIPMENT Protection insured by this device could be compromised in case of wrong use Please follow the provided information lt is highly recommended not to perform any work or maintenance to the internal parts or equipment of the system All internal maintenance or part replacements are to be solely performed by Millipore service technicians Here is some additional information for technical reference Electrical specifications Milli Q Synthesis 230V 50 Hz 0 26 Amps Milli Q Synthesis A10 230V 50 Hz 0 26 Amps The rating and the specifications of all fuses used are listed in Chapter 9 Appendix 1 of this manual The system must be electrically connected to an earth grounded power supply In the event of any problems with this equipment please do not hesitate to contact your local Millipore Service Representative Milli Q Synthesis Milli Q Synthesis ATO TABLE OF CONTENTS CHAPTER 1 INTRODUCTION Matching this manual with your Milli Q 222222222200 222 How to use the keypad and 79 Commonly used abbreviations in this 77 2 70 2 2 25 72 3 OTN F
26. Tel 358 9 804 5110 Fax 4358 9 256 5660 BELGIUM AND LUXEMBOURG Tel 32 2 726 88 40 Fax 32 2 726 98 84 BRAZIL Fax 33 3 88 38 9539 BioPharmaceutical Division Tel 443 1 877 8926 Fax 443 1 877 1654 Laboratory Water Division Tel 33 1 30 12 7000 Fax 33 1 30 12 7180 Tel 03 5442 9711 Fax 03 5442 9736 Life Sciences 9737 BioPharm 9734 Lab Water KOREA Tel 822 551 0990 Tel 08 628 6960 Fax 08 628 6457 SWITZERLAND Volketswil Tel 01 908 30 60 Fax 01 908 30 80 Lausanne Tel 021 641 2550 Fax 011 5548 7923 Tel 09 804 5110 09 256 5660 Tel 603 757 1322 pu Tel 1 800 645 5476 FRANCE Fax 603 757 1711 Taipei Fax 1 800 645 5439 CHINA PEOPLE S Tel 01 30 12 7000 Fax 01 30 12 7180 MEXICO Tel 525 576 9688 Tel 886 2 700 1742 Fax 886 2 755 3267 Hsin Chu City iir OF GERMANY Fax 525 576 8706 Tel 886 3 571 0178 1 Fax 06196 43901 Tel 076 5022000 U K HUNGARY Fax 076 5022436 Tel 01923 816375 Fax 8610 8519 1255 2 Guangzhou Tel 1 205 9784 NORWAY ax Tel 8620 8755 4049 Fax 1 205 9792 Tel 22 678253 U S A Fax 8620 8752 0172 INDIA Fax 22 66 04 60 Tel 781 533 6000 Hong Kong Tel 91 80 839 46 57 POLAND Fax 781 533 3110 161 1932 a Tel 22 669 12 25 IN ALL OTHER COUNTRIES Fax 852 2513 0313 IRELAND 22 663 70 31 Millipore Intertech U S A a Life Sciences and Laboratory Fax 22 663 70 33 Tel 1 781 533 8
27. Tubing or any other type A ATTENTION of tubing on the end of the MilliPak This can compromise the Produci Water quality bacteria can grow in the Tygon Tubing The MilliPak is now installed and rinsed out 4 10 How TO CALIBRATE THE FLOWRATE FROM THE MILLI Q It is possible to calibrate the tlowrate of Product Water from the POU Dispenser Q Make sure the MilliPak is vented of all trapped air Q Make sure the Quantum Cartridge is vented of all trapped air Pressurised Feedwater only Make sure the feedwater Pressure Regulator is set correctly between 1 bar and 0 3 bar Make sure the Milli Q is in PRE OPERATE mode If it is in STANDBY mode then press the OPERATE STANIDBY Keypad Button for about 2 seconds to go to PRE OPERATE mode If the Milli Q is in PRODUCT mode dispensing water then move the POU Dispenser Trigger back to the upright position Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRESET VOLUME 0 00 Press MENU for about 2 seconds INSTALLATION You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the LCD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button for about 2 seconds This will place the Milli Q into STANDBY mode Then press the STANDBY OPERATE Keypad Button again The Mili Q will now be in PRE OPERATE mode Press th
28. an AIR PURGE with the Milli Q system in order to remove all air from the newly installed Q Gard and Quantum Remove the used MilliPak from the POU Dispenser Locate the clear Tygon Tubing and the Barbed Fitting from the Accessories Bag Screw the Barbed Fitting onto the bottom end of the POU Dispenser Do not use any Teflon Tape on the threads of the Barbed Fitting An O ring is located inside the POU Dispenser to insure water tightness A PLENAN between the threads of the POU Dispenser and the Barbed Fitting Push one end of the Tygon Tubing onto the end of the Barbed Fitting Place the other end of the Tygon Tubing into a sink At this time you should have installed the Q Gard Pack Quantum Cartridge Barbed Fitting and the Tygon Tubing The system power should be on The POU Dispenser Trigger should be upright The LCD should be showing STANDBY MAINTENANCE Put the Milli Q into PRE OPERATE mode Press the OPERATE STANDBY Keypad Button for about 2 seconds This will change the Milli Q from STANDBY mode to PRE OPERATE mode See the drawing below for more information PRE OPERATE OPEN THE VALVE CLEANING Press for about 2 seconds Move the POU Dispenser Trigger forward This will place the Milli Q in PRODUCT mode Verify that you have several litres of feedwater i e full Reservoir or full Distribution Loop Bring the POU Dispenser Trigger down towards you You should hear a
29. and has paper and so forth Make sure Milli Q is in PRODUCT mode It is not possible to print while the Milli Q is in PRE OPERATE or STANDBY mode Q Press the MENU Keypad Button for about 2 seconds The LCD will change as shown here PRESET VOLUME 0 00 18 2MQ cm 25 C TOC 4 ppb 7 CLEANING Press MENU for about 2 seconds Press the MENU Keypad Button one more time The LCD will change as shown here SERVICE PRINTER PRESS MEASURE Press MENU Press the MEASURE Keypad Button The Printer will start to print The Milli Q will return to PRODUCT mode automatically SERVICE PRINTER PRESS MEASURE 18 2MQ cm 25 C TOC 4 ppb CLEANING Press MEASURE 8 WHAT DOES THE PRINTOUT LOOK LIKE An example Printout is shown here bi MILLIPORE OK OK K OK Ok SYSTEM SYNTHESIS 10 SERIAL F1JW8765A PROGR VERSION V3 01 QUALITY REPORT DATE JUL 13 01 USER NAME TEMPERATURE 17 8 C 25 C CORRECTION ON PRODUCT 18 2 MQ cm TOC 3ppb APPENDIXES 88 APPENDIXES APPENDIX HOW TO TRANSFER INFORMATION TO A COMPUTER It is possible to transfer download information to a computer from the Milli Q REQUIREMENTS NEEDED A cable is needed to connect between the Milli Q and a computer The Millipore Catalogue number for this cable is COMPCBLO1 This Computer Cable is an accessory for the Mill
30. included in this manual The instructions are included with the replacement UV Lamp Contact Millipore for a copy of these instructions if you would like to see them before ordering a replacement ATO UV Lamp 6 9 How TO CLEAN THE 10 TOC MONITORING DEVICE The ATO TOC Monitoring Device may need to be cleaned sometimes This cleaning does not involve any chemical reagents This cleaning is initiated with the Milli Q software and is simple to perform How LONG DOES THE A10 CLEANING TAKE The A10 Cleaning takes 60 minutes to complete The LCD will show a countdown timer indicating the remaining time until the ATO Cleaning is finished WHY WOULD NEED DO AN A O CLEANING 2 The A10 Cleaning is recommended when 1 the Q Gard and Quantum have been replaced see the next question below 2 the displayed TOC values are fluctuating 3 the displayed TOC values are higher then normally seen 4 Milli Q has been in STANDBY mode or powered off for more than 12 hours WOULD AN A10 CLEANING EVER HAPPEN AUTOMATICALLY An ATO Cleaning will occur automatically after the Q Gard Pack and Quantum Cartridge are exchanged Normally a 5 minute AIR PURGE mode is started after the Quantum Cartridge is replaced When the AIR PURGE is finished the 60 minute ATO CLEANING mode is started See Section 4 7 for more information about the AIR PURGE and the automatic CLEANING mode 2 MAINTENANCE How DO AN 10 CLEANING F
31. is in PRE OPERATE mode The ATO will not perform any measurements when the Milli Q is in STANDBY mode WHAT MAINTENANCE IS INVOLVED WITH THE A10 The ATO uses a small UV light during its TOC analysis mode ATO UV lamp needs to be replaced periodically The normal useful lifetime of the ATO UV Lamp is 1 year The Milli Q system uses a calendar day timer to record age of the AIO UV lamp A service message is prompted after 365 Days EXCHANGE ATO UV to remind you to change the ATO UV lamp The Catalogue Number for the A10 UV Lamp is ZFA10UVOI There is a Cleaning Mode for the ATO This Cleaning Mode can be initiated with the Milli Q software A10 Cleaning mode does not use a chemical reagent of any kind The 10 Cleaning is explained in further detail in the Maintenance Section of this manual DOES THE 10 NEED TO BE CALIBRATED It is recommended to calibrate the ATO once per year The ATO can not be calibrated on site it needs to be calibrated by Millipore The accuracy claims of the TOC measurement are valid for 1 year from calibration ATO UV Lamp is replaced as part of the calibration procedure An annual verification can be performed instead of a complete calibration depending on your requirements Contact Millipore for further information regarding a calibration or verification of the A10 TOC Monitor Device TOC SUITABILITY TEST ACCORDING TO USP 24 lt 643 gt It is possible to perform a TO
32. length An Assembly of Blue Fittings is attached one end of this tubing The Assembly of Blue Fittings has a Screen Filter inside The term Screen Filter will be used for the remainder of this manual fo refer to the Assembly of Blue Fittings Fitting 1 4 inch NPTM on one end and a hose barb on the other end Clear Tygon Tubing Roll of Tetlon Tape D D 3 Elbow shaped fittings black with yellow coloured collar one fitting will be smaller than the other two fittings Allen Wrench 6 sided black wrench Removal Tool used to remove the Sanitisation Port on top of the system cabinet Q Clear tubing 6 mm OD about 2 5 meters in length 22 PRE INSTALLATION ACCESSORIES SAN PORT REMOVAL TOOL Milli Q Synthesis Synthesis ATO 29 INSTALLATION Chapter 4 INSTALLATION 4 1 CONNECTING A SUPPLY FEEDWATER FEEDWATER IS FROM A RESERVOIR Make sure the Reservoir is full of puritied water i e RO Elix water Make sure the Milli Q is located either beside or lower than the Reservoir It is not advisable to locate the Reservoir below the Milli Q If you are using 30 or or 100 Litre Reservoir from Millipore then install a connector fitting which is 1 4 inch NPTM on one end and has an 8 mm tubing insert collar on the other end This connector fitting should be installed on the middle valve located on the bottom side of the 30 60 100 Litre Reservoir The Millipore fitting refe
33. source 2 amp SLO BLO fuse used 230 VAC 10 50 60 Hz 0 26 amp source 1 amp SLO BLO fuse used he source of electrical power should be within 1 meter of the Milli Q The source of electrical power must be earth grounded 20 PRE INSTALLATION FEEDWATER REQUIREMENTS Feedwater Conductivity lt 100 uS cm Q 25 C Feedwater Flowrate The source of feedwater should deliver gt 1 5 LPM Maximum Feedwater Pressure lt 0 3 bar use a Pressure Regulator if necessary Minimum Feedwater Pressure gt 0 1 bar i e reservoir lt gt same level as the Milli Q Feedwater temperature Between 5 C and 35 C Items to note about feedwater ion exchange capacity of the Q Gard Purification Pack and the Quantum Ultrapure Cartridge are a strong function of the conductivity and the dissolved gas level of the Feedwater Source Fouling Index Silt Density Index of the Feedwater when gt 5 can effect the ability of the lon Exchange Resin to remove ions The level of the Milli Q Product Water could be affected by the type of feedwater Contact Millipore for additional information regarding the 3 items noted just above lr is highly recommended to use a feedwater source treated by RO or EDI Millipore RiOs or Elix Water Purification Systems are examples of KO or EDI feedwater sources respectively ENVIRONMENTAL REQUIREMENTS Ambient Storage Temperature of the Milli Q Between 5 C and 40 C Ambient Ope
34. the MilliPak onto the POU Dispenser Turn it until it is handtight Do not overtighten the MilliPak Do not use Teflon Tape on the threads of the MilliPak The A ATTENTION POU Dispenser has an O ring inside which provides a watertight seal Move the POU Dispenser Trigger forwards This will bring the Milli Q system into PRODUCT mode Locate the air vent valve on the top side clear side of the MilliPak Open this slowly but do not remove the air vent from the MilliPak Allow any air on the clear side of the MilliPak to be vented out Dispense about 5 litres of water Make sure all air is purged out Air will not pass through the membrane filter in the MilliPak there AN ATTENTION is trapped air in the MilliPak then a reduction in Product Water flowrate can result Move the POU Dispenser Trigger back to the upright position The Milli Q will go into PRE OPERATE mode after 90 seconds leave the Milli Q in PRE OPERATE mode It is highly recommended not to put Tygon Tubing or any other type AN ATTENTION of tubing on the end of the MilliPak This can compromise the Product Water quality The MilliPak is now installed and rinsed out At this time it is highly recommended to recalibrate the Product Water flowrate from the Milli Q See Section 4 10 How to calibrate for more information Remember to leave the Milli Q in PRE OPERATE mode during times of non use i e evenings weekends holidays MA
35. 000 UF Membrane Cartridge Filter PRODUCT INFORMATION 2 3 DESCRIPTION OF MAIN COMPONENTS INLET SOLENOID VALVE The Inlet Solenoid Valve is used to control the flow of feedwater into the Milli Q system The Inlet Solenoid Valve is open when the system is delivering water from the Point Of Use Dispenser and during Recirculation mode PRESSURE RELIEF VALVE The Milli Q system has Feedwater Pressure Relief Valve inside The purpose of this is to vent out any Feedwater that has a pressure higher than O 75 bar 11 psi This would prevent any excessive Feedwater pressure that could build up in the Milli Q system during Recirculation Mode A piece of tubing is included in the Accessories Bag This tubing is attached to the Milli Q system and than placed in a drain or sink When the incoming Feedwater has a pressure greater than O 75 bar the Pressure Relief Valve will open up and Feedwater will be vented to drain via the attached tubing The water will stop flowing to drain when the Feedwater Pressure drops to less than O 75 bar It a Pressure Regulator is installed on the Feedwater Tubing between the Milli Q and a Loop then it is unlikely that the Feedwater Pressure will get this high The installation of this tubing is described in more detail in Chapter 4 Installation A Milli Q fed from a Reservoir will not need the Pressure Relief Valve tubing A Milli Q fed from Pressurised Pipe a Loop should have the Pressure Relief Valve tubing
36. 30 continuous minutes Water drips out of the MilliPak when you go There is air in the MilliPak Vent the air out back to PRE OPERATE mode from PRODUCT mode You have used the automatic volume dispenser Calibrate the Flowrate of Product Water feature see Section 5 5 The dispensed volume GC raie Purge air from the Quantum Cartridge Vent the MilliPak of trapped air The displayed TOC is xxx ppb The measured TOC value is out of range gt 999 ppb or the last measured TOC value is not stored in the system s memory 82 ORDERING INFORMATION Chapter 8 ORDERING INFORMATION 8 1 CATALOGUE NUMBERS FOR CONSUMABLES Consumable Item Catalogue Number Q Gard 1 Purification Pack QGARDOOR 1 1 box used for RO Elix Milli RX Milli RO distilled Feedwaters Q Gard 2 Purification Pack QGARDOOD2 l box used for DI Service DI Feedwaters organic species removal Q Gard B1 Purification Pack Q GARDOOB l box used specifically for Boron Removal Purification Pack Q GARDOOVX l box used specifically for volatile QTUMOOO X 1 box MilliPak not included used for applications needing trace levels of Quantum Cartridge ions Quantum EX Cartridge QTUMOOOEX 1 box MilliPak not included used for applications needing trace levels of ions and trace levels of organic species QTUMOOOVX 1 box MilliPak not included used for applications needing trace levels of volatile organic species and ion
37. 622 Fax 8621 5306 0838 Water Divisions PUERTO RICO Fax 1 781 533 8630 CZECH REPUBLIC Tel 02 2051 3841 Fax 02 2051 4298 Phone numbers may change INTERNET OR EMAIL Internet Site Address Tel 444 1923 816375 Fax 444 1923 818297 BioPharmaceutical Division Tel 021 883 666 Fax 021 883 048 Tel 787 273 8495 Fax 787 747 6553 See Millipore s Internet site at www millipore com for updated information www millioore com Email www millioore com techservice H2OQmillipore com PRODUCT INFORMATION Chapter 2 PRODUCT INFORMATION 2 1 MILLI Q PRODUCT WATER SPECIFICATIONS WATER PRODUCED BY THE MILLI Q SYNTHESIS OR SYNTHESIS A10 FLOWRATE TOC 0 8 1 2 IPM with MilliPak Express 20 maximum 5 ppb this specification came from test conditions where a Milli Q Synthesis was fitted with a RESISTIVITY Q Gard 1 Purification Pack and Quantum EX minimum 18 0 MQ cm Q 25 C Ultrapure Cartridge and the feedwater came from a Millipore RiOs Water System The feedwater TOC value was lt 50 ppb TOC of the Milli Q PARTICLES Product Water can vary as a function of the feedwater typically 18 2 6 25 lt ml particle size gt 0 22 um MICRO ORGANISMS PYROGENS MUERE lt 1 CFU ml lt 0 001 Eu ml COMPARISON OF MiLLI Q WATER AND ASTM STANDARD SPECIFICATIONS Milli Q Product Water Quality will meet or exceed ASTM Type Standard Specifications for Reagent G
38. 89 SESSIONE I 89 go 89 APRENDI CA DOM 92 APPENDIX BON TO USE AUK EMOTE POU ao A es UP Ste a A 92 ARPENDDCO COMP MODE 4 93 INTRODUCTION Chapter 1 INTRODUCTION 1 1 USING THIS MANUAL MATCHING THIS MANUAL WITH YOUR MILLI Q This manual is intended for use with a Millipore Milli Q Synthesis or Milli Q Synthesis A10 Water Purification System This Owner s Manual is a guide for use during the installation normal operation and maintenance of a Milli Q Synthesis or Milli Q Synthesis ATO Water Purification System It is highly recommended to completely read this manual and to fully comprehend its contents before attempting installation normal operation or maintenance of the Water Purification System You can easily identity your type of Water Purification System if you do not see the Catalogue Number The Milli Q Synthesis and Synthesis ATO Water Purification Systems have an Orange Door on the front cabinet If this manual is not the correct one for your Water Purification System then please contact Millipore TO USE THE KEYPAD AND THE LCD The Keypad and LCD liquid crystal display are located on the front of the Water System Cabinet The Keypad buttons sometimes have a slight delay when
39. ATE mode Leave the Milli Q in PRE OPERATE mode Do not leave it in STANDBY mode unless you are going to perform some sort of maintenance i e changing the Q Gard and Quantum 46 USING THE MiLLI Q POU DISPENSER IN PRE OPERATE MODE POSITION POU DISPENSER IN PRODUCT MODE POSITION Milli Q Synthesis Synthesis ATO 47 USING THE MiLLI Q 5 2 STANDBY PRE OPERATE AND PRODUCT MODE WHAT IS STANDBY MODE STANDBY mode is selected before attempting maintenance on the system For example you would select STANDBY mode before removing the Q Gard Pack The Inlet Solenoid Valve is closed in STANDBY mode The Milli Q will not have an hourly 5 minute recirculation of water in STANDBY mode A Milli Q Synthesis A10 will not perform a TOC analysis during STANDBY mode In STANDBY mode you can move the POU Dispenser Trigger forward and then close it This will open the POU Dispenser Electric Valve for 10 seconds This will allow the system to depressurise An example of when this would be needed is when you are about to remove a Q Gard Pack WHAT IS PRE OPERATE MODE PRE OPERATE mode is selected when the system is not dispensing water For example the Milli Q would be left in PRE OPERATE mode during the evenings and weekends and during other periods of non use The Inlet Solenoid Valve is closed during PRE OPERATE mode The Milli Q will have an hourly 5 minute recirculation of water in PRE OPERATE mode This will enhance the quality of th
40. Analysis Cycle This cycle will continue while the Milli Q is in PRODUCT mode 49 USING THE MiLLI Q 5 4 HOW TO USE THE FOOTSWITCH OPTIONAL ACCESSORY The Footswitch is an optional accessory for the Milli Q system The instructions for installing the Footswitch are inside the shipping box of the Footswitch and are not in this manual The Footswitch can be installed so that you can have either Hands Free operation of the POU Dispenser that comes with the Milli Q system Hands Free operation of a Remote POU Dispenser another accessory is not possible to have one Footswitch controlling 2 different POU Dispensers It is not possible to have two different Footswitches on a single Milli Q System The Milli Q will go from PRE OPERATE mode to PRODUCT mode when the Footswitch is depressed The Milli Q will remain in PRODUCT as long as the Footswitch is depressed VVhen the Footswitch is released the Milli Q will go back to PRE OPERATE mode after 90 seconds 5 5 HOW TO DISPENSE AN EXACT AMOUNT OF PRODUCT WATER It is possible to dispense pre set volumes of water from the Milli Q 0 00 L to 63 75 L 0 25 increments accuracy of this is dependent upon the accuracy of the Flow Calibration performed in Section 4 10 Make sure the Milli Q POU Dispenser Flowrate is calibrated Q Make sure the MilliPak is vented of air Q Make sure the Quantum Cartridge is vented of air Q Make sure you are in PRE OPERATE m
41. Bag Locate the OUT 5 Port on the back of the Milli Q Synthesis or Milli Q Synthesis ATO system Install the 6 mm Elbow into the OUT 5 Port Push it in all the way The use of this elbow fitting will allow the tubing to fit better especially if the system is wall mounted Plug the clear 6 mm OD tubing into the elbow fitting Place the other end of the clear 6 mm OD tubing into a sink or drain Shorten the tubing if necessary UF REJECT TUBING Read the steps above concerning the installation of the Feedwater Tubing Locate the DRAIN 3 Port on the back of the Milli Q Synthesis or Milli Q Synthesis 10 system Measure the distance between this port and a sink or drain The maximum recommended distance is 2 5 meters Remove the red plug that is in the DRAIN 3 Port To do this push in on the collar that holds the red plug in place At the same time pull the red plug out Locate another elbow shaped fitting from the Accessories Bag Install it into the DRAIN 3 Port Push it in all the way The use of this elbow fitting will allow the tubing to fit better especially if the system is wall mounted Install a length of black 8 mm OD tubing into this elbow fitting Place the other end of the UF Reject tubing into a sink or drain 26 INSTALLATION CONNECTING THE POWER CORD Locate the Milli Q Power Switch It is located on the back of the system cabinet It is located just above the Feedwater Tub
42. C Suitability Test with the ATO TOC Monitor Contact Millipore for further information on how to perform a TOC Suitability Test with an A10 TOC Monitor PRODUCT INFORMATION 2 4 TECHNICAL SPECIFICATIONS DIMENSIONS SYSTEM AND CLEARANCE The height width and depth of a Milli Q Synthesis and Synthesis are shown here ma doce 74mm wn 4 20 mm d gt SEP P JI 3 i LL UA Ll 5 R 7705 5 T SITES gt l IIN 445 7 d 9 yri oy F CON 296 gt 778 WEIGHT Milli Q Synthesis Operating weight wetted Q Gard Quantum and MilliPak 16 kg Milli Q Synthesis ATO Operating weight 16 8 kg ELECTRICAL he electrical requirements for a Milli Q Synthesis or Milli Q Synthesis are 120 VAC 10 50 60 Hz 0 5 amp source 2 amp SLO BLO fuse used 230 VAC 10 50 60 Hz 0 26 amp source 1 amp SLO BLO fuse used source of electrical power should be within 1 meter of the Milli Q The source of el
43. E mode and then will start an automatic 60 minute CLEANING CLEANING is a way of flushing out any particles trom the A TO that may have been present Milli Q Synthesis 10 only Allow the ATO CLEANING to count down to minutes The remaining steps of this section apply to both the Milli Q Synthesis and the Milli Q Synthesis ATO remaining air in Quantum Cartridge can be hand purged out now STANDBY PRE OPERATE CLOSE THE VALVE ATO CLEANING 60 Geta screwdriver with a very thin shaft and small head locate the small hole on the top part of the Quantum Cartridge Door Gently insert the screwdriver into the Quantum Cartridge This will open a small vent that will expel any air in the Quantum Cartridge Be very careful when pushing the tip of the screwdriver into the A ATTENTION Vent Hole of the Quantum Cartridge The Vent Hole only needs to be opened a very small amount f all of the air does not expel out do not worry You can repeat this step later after more water has flowed through the Milli Q Remember to have the Milli Q in STANDBY or PRE OPERATE mode E You now need to allow the Q Gard Pack and the Quantum Cartridge to hydrate overnight This helps to produce high quality Product Water Atthis time the MilliPak is not installed The Barbed Fitting and Tygon Tubing should still be attached to the end of the POU Dispenser Leave the Milli Q in PRE OPERAT
44. E mode overnight or for several hours This will aid in rinsing off the purification media inside the Q Gard Pack and the Quantum Cartridge The next morning Bring the POU Dispenser Trigger forward to put the Milli Q into PRODUCT mode Allow about 10 to 15 litres 7 to 10 minutes of PRODUCT mode of water to be dispensed from the Milli Q Bring the POU Dispenser Trigger upright The Milli Q will go into PRE OPERATE mode after 90 seconds Leave the Milli Q in PRE OPERATE mode CO D The Q Gard Pack and Quantum Cartridge are now fully air purged and hydrated Proceed to Section 6 4 for instructions on installing the MilliPak 62 MAINTENANCE INSTALLATION OF THE QUANTUM CARTRIDGE Milli Q Synthesis Synthesis ATO MAINTENANCE INSTALLATION OF BARBED FITTING AND TYGON TUBING PURGING AIR FROM THE QUANTUM CARTRIDGE INSTALLATION AND AIR PURGE OF THE MILLIPAK 64 MAINTENANCE 6 4 HOW TO REPLACE THE MILLIPAK The MilliPak is normally replaced when the Q Gard Pack and Quantum Cartridge are replaced The MilliPak may need to be replaced at an earlier time if it becomes clogged A clogged MilliPak will considerably reduce the Milli Q Product Water flowrate Follow the steps below to replace the MilliPak Q Make sure the Q Gard Pack and Quantum Cartridge have been air purged Make sure they have been hydrated overnight Q Remove the Barbed Fitting and Tygon Tubing from the POU Dispenser Screw
45. IDGE OUT The Red ALARM LED will be flashing The RECIRCULATION display appears for only 5 minutes 4 5 INSTALLATION OF THE QUANTUM CARTRIDGE locate the 2 latches on the front door of the Milli Q Cabinet Push each latch to the left and then open the door Q Remove the 2 yellow plastic inserts that are inside Pull them out and remove them Remove the Quantum Cartridge from its shipping box Confirm that you have the desired type of Quantum Cartridge by viewing the label on the top of the Quantum Cartridge Q Remove the 2 plastic covers on the ports of the Quantum Cartridge There should be a black rubber O ring in each port Make sure these are pushed firmly in place Wet the Quantum Cartridge O rings with water It is preferable to wet them with ultrapure water DO NOT WET THE O RINGS WITH A LUBRICANT SUCH AS OIL OR SILICON GREASE Push the Quantum firmly into place Both the top and bottom ports of the Quantum Cartridge have to be fully seated Close the door Make sure that both the top latch and the bottom latch of the door A ATTENTION are fully closed Each latch should click when it is fully closed The Quantum Cartridge is now installed 4 6 INSTALLATION OF THE TYGON TUBING locate the clear Tygon Tubing and the Barbed Fitting from the Accessories Bag Q Screw the Barbed Fitting onto the bottom end of the POU Dispenser Do not use any Teflon Tape on the threads of the Barbed Fitting ra ATTENTI
46. INTENANCE 6 5 HOW TO SANITISE AND CLEAN THE UF CARTRIDGE HOW OFTEN WOULD NORMALLY SANITISE AND CLEAN THE UF CARTRIDGE The Milli Q Synthesis and Milli Q Synthesis will show an LCD message START SANIT every 4 weeks once per month The yellow Service LED will be blinking also This message is based on a day to day timer THINGS TO KNOW BEFORE YOU SANITISE THE UF CARTRIDGE 1 You will need a minimum of a full 30 L Reservoir fed at 3 LPH i e a full 30 Reservoir fed with Elix 3 or RiOs 3 You will need grams of Sodium Hydroxide NaOH every time you sanitise the system Do not use any type of chlorine for the sanitisation Millipore does not sell NaOH but it is readily available through most Scientific Apparatus Supply Companies You will need the Barbed Fitting and clear Tygon Tubing from the Accessories Bag same items you used when the Q Gard Pack and Quantum Cartridge were air purged and hydrated The Milli Q system will not be able to make Product Water for a minimum of 421 minutes while UF is sanitised and cleaned lt is best to plan to perform the Sanitisation of the UF Cartridge during an overnight or weekend time frame Sodium Hydroxide will form a caustic high pH solution when mixed with water This solution can be very dangerous for your eyes and for your skin Wear Eye Safety Glasses and Laboratory Gloves and other appropriate safety equipment when working with Sodium Hydroxide
47. Milli Q Synthesis and Milli Q Synthesis 10 User Manual Notice The intormation in this document is subject to change without notice and should not be construed as a commitment by Millipore Corporation Millipore Corporation assumes no responsibility for any errors that might appear in this document This manual is believed to be complete and accurate at the time of publication In no event shall Millipore Corporation be liable for incidental or consequential damages in connection with or arising from the use of this manual Copyright 2002 MILLIPORE CORPORATION PRINTED IN FRANCE All RIGHTS RESERVED THIS BOOK OR PARTS THEREOF MAY BE REPRODUCED IN ANY FORM WITHOUT THE WRITTEN PERMISSION OF THE PUBLISHERS Rev 0 06 02 Trademarks Millipore is a registered trademark of Millipore Corporation Elix Q Gard MilliPak and Milli Q are registered trademarks of Millipore Corporation Quantum RiOs and 10 are trademarks of Millipore Corporation Pyrogard is a registered trademark of Millipore Corporation Teflon is a registered trademark of E l du Pont de Nemours amp Co Tygon is a registered trademark of the Norton Company ASTM is a registered trademark of the American Society for Testing and Materials Allen is a registered trademark of the Holo Krome Technology Corporation Santoprene is a registered trademark of Advanced Elastomer Systems SLO BLO is a registered trademark of Littlefuse Inc Windows and EXCEL are r
48. NING 59 Wait for the CLEANING mode to finish The Milli Q will automatically go to PRE OPERATE mode at the end of the ATO CLEANING mode You have finished performing an 10 CLEANING How CANCEL THE 10 CLEANING ONCE IT IS STARTED 2 Press the MENU Keypad Button for about 2 seconds during the ATO CLEANING mode to cancel it The Milli Q will return to PRE OPERATE mode SERVICE A10 PRE OPERATE A10 CLEANING 43 s EE Press MENU for about 2 seconds 6 10 HOWTO CALIBRATE THE MONITORING DEVICE It is recommended to recalibrate or at least to re verify the ATO TOC Monitoring Device once a year The Milli Q will not display any type of message indicating that the 10 needs to be recalibrated or veritied The ATO TOC Monitoring Device can not be recalibrated on site It is necessary to contact Millipore when you need to have the 10 recalibrated Please note that if the ATO is sent to Millipore for recalibration then the UV Lamp will also be replaced by Millipore as part of the recalibration procedure 4 MAINTENANCE 6 11 HOW TO PERFORM AN AIR PURGE An Air Purge is performed when there is trapped air in the UF Cartridge Trapped air will reduce the Product Water flowrate from the Milli Q Air Purge will allow the trapped air to be sent out of the Milli Q system via the UF Reject tubing An Air Purge is also useful in flushing out any trapped Pyrogens bacteria particles fro
49. ON An O ring is located inside the POU Dispenser to insure water tightness between the threads of the POU Dispenser and the Barbed Fitting Q Push one end of the Tygon Tubing onto the end of the Barbed Fitting Place the other end of the Tygon Tubing in a sink 30 INSTALLATION INSTALLATION OF THE QUANTUM CARTRIDGE Milli Q Synthesis Synthesis ATO 31 INSTALLATION 4 7 PURGING THE AIR FROM THE SYSTEM At this time you should have installed the Q Gard Pack Quantum Cartridge Barbed Fitting and the Tygon Tubing The system power should be on The POU Dispenser Trigger should be upright The LCD should be showing PRE OPERATE Verity that you have several litres gt 15 litres of feedwater i e full Reservoir or full Distribution Loop Open any valves on the feedwater supply i e valve on the bottom of the Reservoir Bring the POU Dispenser Trigger down towards you You should hear a sharp click noise This is the opening of the Inlet Solenoid Valve Water will start flowing out of the UF Reject tubing Q The LCD will change and will look like PRE OPERATE PRODUCT STANDBY OPEN THE VALVE AIR PURGE 5 mn CLOSE THE VALVE let the AIR PURGE continue for its 5 minute duration It will count down to minutes 5 4 mn Pressurised Feedwater Only Check the Pressure Gauge on the Pressure Regulator While water is flowing through it the Pressure Gauge should show 0 3 bar ff it is not set
50. OPERATE Keypad Button again The Milli Q will now be in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Service Software Press the MENU Keypad Button 5 times 6 times for a Milli Q Synthesis You should press the MENU Keypad button each time Stop when you see the LANGUAGE under SERVICE OPTIONS display VOLUME SERVICE PRINTER SERVICE CALIB Presi SERVICE OPTIONS time LANGUAGE ENGLISH Press the OPERATE STANDBY Keypad once The PROD UNIT choice will be shown SERVICE OPTIONS PROD UNIT SERVICE OPTIONS LANGUAGE ENGLISH Press OPERATE STANDBY 39 INSTALLATION Press the CLEANING Keypad Button to change the PROD UNIT from MO cm to uS cm SERVICE OPTIONS PROD UNIT uS cm PRE OPERATE Press MENU for about 2 seconds When the Milli Q is put into PRODUCT mode the LCD will look like PRE OPERATE 25 Note that a Conductivity Measurement of 0 055 uS cm is the same as a Resistivity Measurement of 18 2 MQ cm You have finished changing to units of Conductivity AO INSTALLATION 4 13 HOW TO SHOW NON TEMPERATURE COMPENSATED RESISTIVITY OR CONDUCTIVITY VALUES It is possible to show non temperature compensated Resistivity or non temperature compensated Conductivity Product Water values on the LCD WHAT IS TEMPERATURE COMPENSATION Sup
51. SE REMEDY No voltage at Wall Electrical Outlet e Check Voltage at Wall Electrical Outlet Power cord not plugged into Milli Q e Confirm that the Power Cord is plugged in System not turned on e Confirm Power Switch is turned on Main Power Fuse blown Replace Main Power Fuse See Chapter 9 Appendix A Problem with internal component Contact Millipore THE PROBLEM IS THERE IS AN ERROR NUMBER ALARM DISPLAYED CAUSE REMEDY SYSTEM ERROR 1 displayed The voltage going to the Motor is gt 49 VDC CONTACT MILLIPORE The Milli Q can still be used SYSTEM ERROR 2 displayed The measured temperature is 0 C e The Milli Q can still be used SYSTEM ERROR 3 displayed The measured temperature is gt 45 C The system will still produce high quality water if the The Milli Q can still be used water is not really this warm i e Error coming trom a Thermistor problem Is the feedwater really this warm 2 CONTACT MILLIPORE SYSTEM ERROR 4 displayed The measured Resistivity Value 25 C is between 3 5 and 2 5 See the Section above The problem is low Resistivity of the Product Water for further information 9 TROUBLESHOOTING CONTINUATION OF ERROR NUMBER ALARM DISPLAYED CAUSE REMEDY SYSTEM ERROR 5 displayed The measured Resistivity Value 25 C is gt 65 5 The displayed Resistivity The Milli Q can still b
52. SERVICE AGE CARTR 0 DAYS SERVICE AGE UV LAMP 0 DAYS Milli Q Synthesis 10 only Press the OPERATE STANIDBY Keypad Button once to change to the age of the ATO UV Lamp The AGE of the ATO UV the small UV Lamp on ATO device is Days in the display below SERVICE AGE UV LAMP 0 DAYS SERVICE AGE UV A10 0 DAYS Escape the Customer Service Software by pressing the MENU Keypad Button for about 2 seconds You should be back to PRE OPERATE mode You have finished viewing the age of the consumable items 53 USING THE MiLLI Q 5 7 How TO UNDERSTAND MESSAGES It is possible for various messages to be displayed on the Milli Q LCD while you are using the Milli Q While a message is being displayed either the Yellow Service LED or the Red Alarm LED can be blinking The table below provides a summary of these messages what they mean and what to do when you see them You may also refer to Chapter 7 Troubleshooting for more information about these messages and other troubleshooting items Please contact Millipore if you desire more information regarding what to do when a message appears on Milli Q Message and System Status EXCH CARTRIDGES You can still use the system if the water quality resistivity is ok START SANIT EXCH UF TOC SETPOINT You can still use the system if the water quality resistivity and TOC is fine for your application CARTRIDGE OUT The
53. T mode mode VIEWING TEMPERATURE 18 2 cm 25 C Milli Q Synthesis PRODUCT 18 2MQ cm 25 C TOC 3 ppb Mili Q Synthesis PRODUCT mode Press the MEASURE Keypad Button while the Milli Q is in PRODUCT mode 18 2MQ cm 25 C TOC 4 ppb Milli Q Synthesis or Milli Q Synthesis A 10 in PRODUCT mode PRESS MEASURE TEMP 19 1 4 ppb Milli Q Synthesis or Milli Q Synthesis 10 showing the temperature The temperature will be displayed for about 10 seconds The LCD will return to the resistivity display VIEWING TOC The is only displayed if you have a Milli Q Synthesis 10 system The TOC of the Milli Q Product Water is measured about every 5 minutes When you go from PRE OPERATE mode to PRODUCT mode a TOC Analysis is started The displayed will not change until the next Analysis is completed The TOC measurements will be repeated continuously during PRODUCT mode The range of TOC values is from 1 ppb to 999 ppb in 1 ppb increments A display of xxx ppb means that the TOC value measured is out of range 18 2 0 25 C TOC 4 ppb TEN ABOUT 5 MINUTES AFTER ENTERING This is the previously measured PRODUCT MODE value It was just measured in PRODUCT mode or it was measured in the last hour of PRE OPERATE mode 18 2 25 C TOC 6 ppb new TOC value is displayed after an ATO TOC
54. VDC or gt 39 VDC This is also the Power Supply for the Solenoid Valve in the POU Dispenser USING THE MiLLI Q What to do Turn off the electrical power Turn it on 20 to 30 seconds later the message appears again then contact Millipore Replace the UV Lamp Replace the UV Lamp Contact Millipore Contact Millipore Check the feedwater temperature lower if necessary Contact Millipore it the measured temperature is incorrect Contact Millipore for assistance Dispense water from the Milli Q to remove any air bubbles that could be trapped in the Resistivity Sensor Cell Contact Millipore if the message continues Contact Millipore 99 Message and System Status SYSTEM ERROR 8 The POU Dispenser will not dispense water You will not be able to dispense water SYSTEM ERROR 10 You may continue to use the Milli Q A10 ERROR 4 You may continue to use the Milli Q A10 ERROR 5 You may continue to use the Milli Q A10 ERROR 6 You may continue to use the Milli Q A10 ERROR 7 You may continue to use the Milli Q A10 ERROR 9 You may continue to use the Milli Q The electrical intensity being sent to the UV Ballast Power Supply on the Inteface PC Board is 5 mA or gt 950 mA This is also the Power Supply for the Solenoid Valve in the POU Dispenser An error occurred with data transfer to or from the Milli Q microprocessor EZProm ATO PCB E Prom defective ATO
55. abelled as FEED 1 this lettering is located just above the collar of the port may be difficult to see unless you are close to the system Make sure the Feedwater Tubing is connected to the FEED 1 Port A ATTENTION Make sure the Feedwater Tubing is not connected to the DRAIN 3 Port the right side 8 mm OD Port Remove the red plug that is in the FEED 1 Port To do this push on the collar that holds the plug in place At the same time pull the Red Plug out Locate the elbow shaped fitting trom the Accessories Bag Install it into the FEED 1 Port Push it in all the way The use of this elbow fitting will allow the tubing to fit better especially if the system is wall mounted Plug the Feedwater Tubing into the elbow fitting installed in the FEED 1 Port lt your feedwater is from a reservoir then plug in the end of the tubing that is originally attached to the bottom of the Reservoir If your teedwater is from a Pressurised Pipe then plug in the end of the tubing that is initially attached to the outlet of the Pressure Regulator FEEDWATER PRESSURE RELIEF TUBING This procedure does not need to be done if the Milli Q is being fed from a Reservoir It is highly recommended to perform this procedure if the Milli Q is being from a pressurised source such as a loop Locate the roll of clear 6 mm OD tubing that came in the Accessories Bag Locate the smallest elbow shaped fitting from the Accessories
56. about the various consumable items can be found in Sections 2 2 and 2 3 Item or action Maintenance needed Q Gard Pack Replacement When the system resistivity or See Section 6 2 TOC values are outside of specification or the EXCH CARTRIDGE message is displayed Quantum Cartridge Replacement Replace when the Q Gard Pack See Section 6 3 is replaced MilliPak Replacement Replaced when the Quantum See Section 6 4 Cartridge and Q Gard Pack are replaced or when the Product Water Flowrate drops Sanitisation and cleaning of Cleaning Every 4 weeks See Section 6 5 the UF Cartridge Screen Filter 2 times a year or as necessary See Section Flow Calibration Perform a calibration When the MilliPak is See Section 4 1 1 replaced After an AIR PURGE Alter a dirty UF Cartridge is cleaned Periodically POU Dispenser Arm Tightening See Section 0 7 10 UV Every 305 Days See Section 6 8 A10 Cleaning Perform a cleaning Automatic when the Quantum is See Section 6 9 replaced As necessary A10 Calibration Having it calibrated Every 365 Days See Section 6 10 Air Purge of UF Cartridge Perform an Air Purge Automatic when the Quantum is See Section 6 11 replaced As necessary UV Lamp Every 305 Days See Section 0 12 MAINTENANCE 6 2 HOW TO REPLACE THE Q GARD The Q Gard is normally replaced every 180 Days or when the Product Water quality is not optimal i e drop in Resistivity increase TOC ioni
57. am which is plumbed via a piece of 8 mm OD tubing trom the back of the Milli Q to a sink or a drain This stream is used to transport the bacteria pyrogens particles that are rejected by the UF Cartridge The flow through this piece of tubing is controlled by a solenoid valve This valve is only open for 30 seconds every 3 hours of PRE OPERATE mode or when the AIR PURGE mode is active This valve will also open for portions of the Sanitisation Mode RESISTIVITY SENSOR RESISTIVITY AND TEMPERATURE MEASUREMENTS The resistivity sensor is used to measure the electrical resistivity of the Milli Q Product Water Additionally a thermistor temperature sensor is located in the resistivity sensor The temperature displayed on the Milli Q LCD during PRODUCT mode is measured by this thermistor TEMPERATURE COMPENSATION CONDUCTIVITY MEASUREMENTS The resistivity and temperature are measured while water is flowing through the sensor The Milli Q microprocessor will then temperature compensate the resistivity to a 25 C value lt is possible to use the Milli Q software to display non temperature compensated resistivity lt is also possible to display conductivity uS cm temp compensated or non temp compensated on the LCD by using the Milli Q software The software can be changed by using the Keypad RESISTIVITY VERIFICATION ACCORDING TO USP 24 6455 A Millipore Field Service Representative can perform resistivity and temperature measurement
58. and the back of the Milli Q Allow some extra distance so the Milli Q could be rotated or moved without stretching the tubing Cut the appropriate length of 8 mm tubing as determined above The remainder of the length of the black 8 mm tubing will be used for the UF Reject tubing You will now need to install the Feedwater Pressure Regulator Millipore Catalogue Number ZFMQOOOPR locate the Pressure Regulator Turn it over so you can see the arrow that indicates the direction of water flow through the Pressure Regulator It is important not to reverse the water flow through the Pressure Regulator The Pressure Regulator is installed between the Screen Filter now attached to the pipe end and the back of the Milli Q You will check and or set the Pressure Regulator later see Section 4 7 below Normally the Millipore Pressure Regulator is pre set to 0 3 bar and will not need adjustment You may want to flow some feedwater through the tubing and Pressure Regulator to check for leaks 24 INSTALLATION CONNECTION TO A PRESSURIZED PIPE 25 INSTALLATION 4 2 CONNECTION OF TUBING AND THE POWERCORD FEEDWATER TUBING Rotate the Milli Q so you can see the back of the system cabinet Look below the place where the Power Cord would be plugged in You will see some holes ports where tubing can be plugged The large ports are 8 mm in OD The smaller ports are 6 mm in OD Locate the left side 8 mm Port l
59. ange resins may have a high level of organic particulate and colloidal contamination The Millipore Catalogue Number for a Q Gard 2 is QGARDOOD2 See Section 8 1 for more information PRODUCT INFORMATION WHEN DO CHANGE THE Q GARD PURIFICATION PACK The decision to change a Q Gard Pack is based upon time calendar days with a Milli Q Synthesis system The Milli Q Synthesis will indicate a message EXCH CARTRIDGES after 180 Calendar Days The Milli Q Synthesis ATO will never display a message EXCH CARTRIDGES It is up to the user to change the Quantum and MilliPak based upon resistivity and TOC values UV LAMP The dual wavelength UV Lamp emits light at 185 nm for TOC reduction and 254 nm Germicidal action The UV Lamp is used to kill bacteria and to reduce the levels of organic molecules in the water stream between the Q Gard Pack and the Quantum Cartridge The UV Lamp has a Millipore Catalogue Number of ZMQUVLPO1 WHEN DO CHANGE THE UV LAMP It is recommended to change the UV lamp every 365 Days once per year The Milli Q LCD will show a message EXCHANGE UV after 365 Calendar Days indicating it is time to replace the UV Lamp QUANTUM The Quantum Ultrapure Cartridge is used to remove trace levels of ions and organic molecules WHAT ARE THE DIFFERENT TYPES OF QUANTUM CARTRIDGES The Quantum IX contains only Mixed Bed lon Exchange resin This type of Quantum Cartridge is used when maintain
60. aximum recommended age of the A10 UV Lamp is 365 days The maximum recommended age of the UV Lamp is 365 Days 1 year Follow the steps below to view the age of the consumable items Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 CLEANING Press MENU for about 2 seconds You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the CD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button for about 2 seconds This will place the Milli Q into STANDBY mode Then press STANDBY OPERATE Keypad Button again The Milli Q will now be in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Service Software Press the MENU Keypad Button 2 times PRESET VOLUME SERVICE PRINTER SERVICE AGE m CARTR 0 DAYS Press MENU each time 22 USING THE MiLLI Q Q Stop when you see the AGE display In the example above the AGE of the Cartridges CART is O Days installed in the last 24 hours This is referring to both the Q Gard and the Quantum It is being assumed that the MilliPak was changed when the and Quantum were changed Q Press the OPERATE STANIDBY Keypad Button once to change to the age of the UV Lamp The AGE of the UV lamp is O Days in the display below
61. c breakthrough For Milli Q Synthesis Systems A Service Message EXCH CARTRIDGES will be shown after 180 Calendar Days For Milli Q Synthesis 10 Systems The Milli Q Synthesis ATO systems will not display a message EXCH CARTRIDGES lt is up to the user of the Milli Q system to verity that the Resistivity and TOC values of the Product Water are still within specitication When the Q Gard is replaced the 180 Day Age is reset to O Days This will remove the EXCH CARTRIDGES message trom the LCD Follow the steps below to replace the Q Gard Pack Removing the used Q Gard Q Place the Milli Q into STANDBY mode See Section 5 1 for more information if necessary Q While in STANDBY mode move the POU Dispenser Trigger forward This will open the electric valve inside the POU Dispenser Any residual water pressure will be released Allow any water to flow trom the POU Dispenser in STANDBY mode Move the POU Dispenser Trigger back to the upright position locate Q Gard on the front right side of the Milli Q Locate the Pack Adapter Lid at the top of the Q Gard up Pack Adapter Lid and remove the Metal clip the metal rod Gently pull the Q Gard from the metal rod Installing the new Q Gard Remove the Q Gard from its shipping box Verity the Millipore Catalogue Number by looking at the sticker on top of the Q Gard Remove the plastic covers on the 2 ports of the Q Gard Pack look inside the ports to l
62. ct Millipore about changing the The Milli Q can still be used TOC Setpoint CARTRIDGE OUT e Either the Q Gard Pack or the Quantum Cartridge is not pushed in far enough or is absent NO FEED WATER Someone has installed a level sensor device to the Milli Q level of Feedwater is too low according to the level sensor device REBOOT SYSTEM e The AIO has been to process a TOC Analysis unsuccesstully for 15 minutes The Milli Q can still be used e Turn off then on the electrical power to the Milli Q Contact Millipore if this frequently occurs EXCHANGE A10 UV e The small UV lamp on the ATO TOC Monitoring Device has been installed for 365 Days The Milli Q can still be used e You can continue to use the system to produce high quality water until the UV Lamp is replaced EXCH UF CARTR You can continue to use the system to produce high quality water Contact Millipore TROUBLESHOOTING OTHER TROUBLESHOOTING ITEMS WHAT HAPPENED REMEDY Nothing shows up on the Printer The Printer will not print out Temperature and Resistivity values unless the system is in PRODUCT mode Wrong Baud Setting on Milli Q Contact Millipore The Printer is not plugged into the Milli Q system System stops dispensing water after 30 minutes Perfectly normal The Milli Q will stop dispensing water from the POU after 30 continuous minutes Contact Millipore if you want to dispense water for more than
63. ctrical continuity with an Ohmmeter Place the Fuse Holder back into the Milli Q System Put the Power Cord back in Turn on the Power Switch 4 The LCD will show the type of system the system serial number and software version for a few seconds Wait about 10 seconds for this fo go away 5 Place the system back to PRE OPERATE mode or whatever mode it was previously in CONTACT MILLIPORE IF THE MAIN POWER FUSE BLOWS AGAIN A ATTENTION 85 APPENDIXES REPLACEMENT OF MAIN POWER FUSE Milli Q Synthesis Synthesis 86 APPENDIXES APPENDIX 2 TO TRANSFER INFORMATION TO A PRINTER It is possible to transfer download information to a printer from the Milli Q REQUIREMENTS NEEDED A cable is needed to connect between the Milli Q and a printer The Millipore Catalogue number for this cable is PRNTCBLO1 This Printer Cable is an accessory for the Milli Q and needs to be ordered separately A Printer with a Serial Port is necessary is not possible to use Parallel Transmission from the Milli Q Any 20 24 Column Serial Port Printer can be used An example of a Serial Port Printer that has been used with Milli Q systems is the Epson LX 300 WHAT TO DO Make sure the Printer Cable is installed between the Milli Q and the Printer The installation instructions for this cable are not provided in this manual The installation instructions come with the Printer Cable Make sure the Printer is on line
64. d Resistivity or Conductivity due to the fact that these two parameters are not measured at the same time COMP MODE 2 is a setting that gives the actual temperature compensated Resistivity or Conductivity values ln some operating conditions the feed water can be warmer or cooler than the water temperature inside the Milli Q This can cause small fluctuations of the resistivity and Conductivity values Resistivity values could fluctuate between 18 0 MQ cm and 18 4 MQ cm 25 C while the actual resistivity value is 18 2 MQ cm 25 C The COMP 2 setting should be used in applications that require the detection of trace ionic levels or when performing the verification of the Milli Q Resistivity Meter Operation with an independent calibrated Resistivity Meter o
65. droxide Pellets Additionally make sure that the UF Reject Tubing is in a sink or drain and that it is fastened securely in place Remove the MilliPak from the POU Dispenser Screw the Barbed Fitting onto the end of the POU Dispenser Attach the clear Tygon Tubing to the Barbed Fitting Place the other end of the Tygon Tubing into a sink or drain Q While in STANDBY mode press the CLEANING Keypad button for about 2 seconds The display will change as shown here SAN CYCLE Press for about 2 seconds Q Wait about 10 seconds The LCD will now prompt you to OPEN THE VALVE SAN CYCLE SAN CYCLE OPEN THE VALVE Open the valve by moving the POU Dispenser Trigger forward Water will come out of the Tygon Tubing for a while A 421 minute timer will be shown Make sure the POU Dispenser Trigger is pulled forward It this is not done then the timer will not move from the 421 mn position SAN CYCLE SAN CYCLE 420mn OPEN THE VALVE Wait until the timer has reached 400 minutes VVhen timer is at 400 mn it will ask you to Close The Valve Bring the POU Dispenser Trigger back to the upright position the PRE OPERATE position if you were using the system to get Product Water The Close The Valve message will go away and the timer will count down from 400 mn SAN CYCLE 400mn SAN CYCLE 399mn CLOSE THE VALVE 6 MAINTENANCE It is very important that the POU Dispenser is closed now Th
66. e 4 6 5 7 76 4 Internet 4 CHAPTER 2 PRODUCT INFORMATION initiis brit n 5 ILIS PECI e Em J Water produced by the Milli Q Synthesis or Synthesis A gt n E o CORAM 5 js D 1 5 90 M X V A J 5 Comparison of Milli Q Water and ASTM Standard Specifications gt 2 2 SCHEMATIC OF MAIN COMPONENTS 6 2 3 DESCRIPTION OF MAIN COMPONENTS 5 8 7 uo CUM EE eso Ev a EE yt d X gt ee What are the different types of Q Gards 6 K When do change the Q Gard Purification Pack 6
67. e Rubber ABS Poly Acrylonitrile Butadiene Styrene POM Polyoxymethylene NBR Nitrile Rubber Acrylonitrile Butadiene Rubber PC Polycarbonate PP Polyoropylene PTFE Polytetralluoroethylene SAN Poly Styrene Acrylonitrile PES Polyethersullone PPO Polyphenylene Oxide PRE INSTALLATION Chapter 3 PRE INSTALLATION 3 1 PRE INSTALLATION CHECKLIST The installation of your Milli Q will go much easier if certain pre installation requirements are met and followed The checklist below be used to facilitate the pre installation of your Milli Q system You can refer back to this checklist as you read the sections on Optional Equipment Installation Requirements and Unpacking the Milli Q Box 0 D D 0 D D D Do you have a Q Gard Purification Pack Do you have a Quantum Ultrapure Cartridge 2 Do you have a MilliPak Do you have a Milli Q and all items in its Accessories Bag Do you have a source of electrical power close enough to the Milli Q ls the electrical source earth grounded 9 Are you feeding with a Reservoir 2 if feeding from a pressurised pipe see below 15 the reservoir full of water 2 15 the source of water filling the reservoir fully operational 2 Does the reservoir have an 8 mm tubing connection on one of its valves Are you feeding the Milli Q from a pressurised pipe loop Do you have a pressure regulator ready to connect between
68. e MENU Keypad Button again for 2 seconds to enter the Customer Service Software Press the MENU Keypad Button 4 times Stop when you see the FLOW MEASURE display PRESET VOLUME SERVICE PRINTER SERVICE AGE SERVICE CALIB 7 Press MENU PRESS MEASURE each time Place a 2 Graduated Cylinder under MilliPak If you do not have a 2 L Graduated Cylinder then use a container which could hold up to 2 of water Use an accurate measuring device to measure the total water that was dispensed from the Milli Q Q Bring the POU Dispenser Trigger down Press the MEASURE Keypad Button FLOW MEASURE FLOW MEASURE PRESS MEASURE a DISPENSING 1 S The Milli Q will dispense water for 60 seconds Wait until this is finished The timer will count up from second to 60 seconds When the 60 second timer is finished the Flow Calibration Factor display will be shown Measure the total volume of water in liters dispensed from the Milli Q Use the Arrow Keypad Buttons the MEASURE and CLEANING Keypad Buttons to change the FLOW value to the amount of dispensed water 30 INSTALLATION In the example below you measured 1 15 LPM The tlow measured during the manufacturing of the Milli Q was 1 00 LPM SERVICE CALIB FLOW 1 001 mn SERVICE CALIB gt FLOW 1 151 mn 0 CLEANING Flow Calibration Flow you measured Use arrow keypad from Factory buttons Move the POU Dispenser T
69. e Product Water delivered from the Milli Q A Milli Q Synthesis ATO will perform a single TOC analysis immediately following the hourly 5 minute recirculation of water The Inlet Solenoid Valve is open during RECIRCULATION mode The Milli Q will have a 30 second FAST FLUSH mode every 3 hours of PRE OPERATE mode The FAST FLUSH mode cleans the feedwater side of the UF Cartridge This aids in reducing any built up layers of bacteria pyrogens and colloids WHAT 16 PRODUCT MODE PRODUCT mode is selected when you want to dispense water or when you want to get ready to dispense water from the Milli Q Product mode is when you can see the resistivity and temperature of the Milli Q product water This is when you can see the Resistivity and Temperature of the Milli Q Product Water This is when you would see the TOC values with Milli Q Synthesis systems PRODUCT mode occurs because the POU Dispenser Trigger was moved forward The Inlet Solenoid Valve is open in PRODUCT mode The Milli Q will dispense for a maximum of 30 continuous minutes in PRODUCT mode Contact Millipore it you need to dispense for more than 30 continuous minutes During PRODUCT mode there is no water coming out of the UF Reject tubing on the back of the Milli Q system 48 USING THE MiLLI Q 5 3 HOWTO VIEW THE RESISTIVITY TEMPERATURE AND TOC VIEWING RESISTIVITY The Resistivity MQ cm 25 of the Milli Q Product Water is seen while the Milli Q is in PRODUC
70. e Sanitisation A ATTENTION timer will not count down from 400 minutes until the valve is kept closed a When the timer reaches 1 mn the Milli Q will automatically go into PRE OPERATE mode SAN CYCLE Imn PRE OPERATE The Sanitisation and Cleaning of the UF Cartridge is now finished The water inside the Milli Q will be recirculated for 5 minutes every hour of PRE OPERATE mode When you use the system i e the morning after the UF was Sanitised dispense enough water until the Resistivity values are satisfactory Remember to leave the Milli Q in PRE OPERATE mode during times of non use i e evenings weekends holidays 68 MAINTENANCE SANITISATION OF THE UF 69 MAINTENANCE 6 6 HOW TO CLEAN THE SCREEN FILTER The Screen Filter is located in the Assembly of Blue Fittings that came in the Accessories Bag from the Shipping Box The purpose of the Screen Filter is to prevent a large particle or other debris from entering the Inlet Solenoid Valve of the Milli Q System This will allow the Inlet Solenoid Valve to open and close correctly If the Screen Filter becomes blocked with debris clogged then feedwater will not flow freely to the Milli Q It is recommended to clean the Screen Filter twice a year or whenever it may have become clogged An example of this would be if there was a large amount of debris introduced into the feedwater supply i e plumbing work done on the feedwater pipe
71. e Software Press the MENU Keypad Button 5 times 6 times for a Milli Q Synthesis ATO Stop when you see the LANGUAGE under SERVICE OPTIONS display PRESET VOLUME l SERVICE FRINTER SERVICE AGE 2 FLOW MEASURE Press MENU ium S each time LANGUAGE ENGLISH Use the Arrow Keypad Buttons to change the language Q Press the MENU Keypad Button for about 2 seconds to return to PRE OPERATE mode PAUSE i e you want to see French o idi PRE OPERATE in French SERVICE OPTIONS LANGUE FRANCAIS Press MENU each time You have finished changing the displayed language 38 INSTALLATION 4 12 TO SHOW EITHER OR uS CM RESISTIVITY OR CONDUCTIVITY UNITS It is possible to display Conductivity Units on the Milli Q LCD Conductivity uS cm is the reciprocal of Resistivity Follow the steps below to change from a Resistivity Display to a Conductivity Display Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 x Press MENU for about 2 seconds Q You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the CD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button for about 2 seconds This will place the Milli Q into STANDBY mode Then press the STANDBY
72. e system power When the LCD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button for about 2 seconds This will place the Milli Q into STANDBY mode Then press the STANDBY OPERATE Keypad Button again The Milli Q will now be in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Service Software INSTALLATION Q Press the MENU Keypad Button 5 times 6 times for a Milli Q Synthesis ATO Stop when you see LANGUAGE under SERVICE OPTIONS display PRESET VOLUME SERVICE PRINTER SERVICE CALIB Press for 1 second SERVICE OPTIONS each time LANGUAGE ENGLISH Press the OPERATE STANDBY Keypad twice 2 times The RES COMP choice will be shown SERVICE OPTIONS PROD UNIT SERVICE OPTIONS RES COMP MODE 1 SERVICE OPTIONS LANGUAGE ENGL I SH CLEANING Press OPERATE STANIDBY 2 times Press the CLEANING Keypad Button twice to change MODE 1 to OFF Resistivity Temperature Compensation will now be off SERVICE OPTIONS RES COMP MODE 1 SERVICE OPTIONS RES COMP OFF 42 INSTALLATION Q Press the MENU Keypad Button for about 2 seconds fo return to PRE OPERATE mode SERVICE OPTIONS RES COMP OF F PRE OPERATE Press MENU for about 2 seconds When the Milli Q is in PRODUCT mode POU Dispenser Trigger forward the Display will look like PRE OPERATE 31 8
73. e the POU Dispenser Trigger forward and then back up This will place the Milli Q in PRODUCT mode but water will not be dispensed at the moment very small amount of water i e 5 ml may be dispensed out It is recommended to dispense about 150 to 200 ml of Product Water to the drain or into a sink every morning After this use the Milli Q Product Water for your specific application NOTE If you are using the Milli Q frequently i e few times an hour then you will not have to dispense 150 to 200 ml of Product Water to the drain When the green LED stops blinking move the POU Dispenser Trigger forward to dispense water It will stop blinking when the Product Water Resistivity compensated to 25 C is greater than the Resistivity Setpoint and less than the TOC setpoint ATO system only Normally the Resistivity Setpoint is 16 0 MQ cm It is recommended but not necessary to wait until the green LED stops blinking on the POU Dispenser The Milli Q will dispense water continuously for a maximum of 30 minutes After 30 continuous minutes the Milli Q will stop dispensing water and will go into STANDBY mode Contact Millipore if you need to dispense water for more than 30 continuous minutes When you are finished dispensing water move the POU Dispenser Trigger back to the upright position The Milli Q will continue to operate but will not dispense water for 90 seconds After 90 seconds the Milli Q will automatically go to PRE OPER
74. e used may not show gt 18 2 MQ cm Air in the Product Water tubing near the Resistivity Sensor can cause this Make sure the Quantum Cartridge is Air Purged See Section A 7 for more information SYSTEM ERROR 7 displayed Contact Millipore The POU Dispenser will not dispense water You will not be able to dispense water SYSTEM ERROR 8 displayed Contact Millipore The POU Dispenser will not dispense water You will not be able to dispense water SYSTEM ERROR 10 displayed There was a problem reading or writing data to the Data Storage Prom E Prom The Milli Q can still be used Placing the system into STANDBY mode then back to PRE OPERATE mode will erase this message for a few days The system will still produce high quality water Continue to use the system Contact Millipore to have this error fixed A10 ERROR O 1 E Prom defective Turn off on the Milli Q and dispense water for gt 6 minutes the message continues contact Millipore A10 ERROR 1 ATO A D converter defective Turn off on the Milli Q and dispense water for gt 6 minutes lf the message continues contact Millipore A10 ERROR 2 ATO Thermistor defective Turn off on the Milli Q and dispense water for gt minutes If the message continues contact Millipore A10 ERROR 3 Problem occured with temperature compensation Turn off on the Milli Q dispense water for gt minutes the message continues contact Millipore A10
75. ectrical power must be earth grounded MEASUREMENT RANGES FOR TOC RESISTIVITY CONDUCTIVITY AND TEMPERATURE The Milli Q can display various Product Water quality parameters The range of measurement of each parameter is written below Resistivity Measurement Range 2 4 18 2 compensated to 25 C values Conductivity Measurement Range 0 055 0 294 5 Temperature Measurement Range 0 45 C not the system temperature operating range TOC Measurement Range 999 ppb MATERIALS CONSTRUCTION PRODUCT INFORMATION The compositions of the components that contact water are shown in the table below Fittings PE PA PVDF m MilliPak 40 Housing PVDF Membrane MilliPak Express 20 SAN Housing PES Membrane Pack Adapter where Q Gard plugs in POU Valve POM NBR Seal Stainless Steel PTFE Diaphragm Santoprene PTFE Valves EPDM Q Gard Pack PP tubes PE EPDM O rings Quantum Cartridge Polypropylene tube endcaps EPDM O rings Resistivity Cell Stainless Steel Screen Filter Stainless Steel Tubing Inserts Rubber O ring stainless steel collar PA insert UF Cartridge Membrane UF Cartridge Housing UV lamp Ultrapure Quartz Glass UV lamp Housing 316 Stainless Steel NoisE LEVEL The Milli Q has a noise level of 42 dB at a distance of PE Polyethylene PA Polyamide PVDF Polyinylidene Fluoride EPDM Fihylene Propylen
76. egistered trademarks of Microsoft Corporation All other trademarks are trademarks of their respective manufacturers Milli Q Synthesis Milli Q Synthesis ATO Milli Q Synthesis and Milli Q Synthesis 10 230V version European version DECLARATION OF CONFORMITY EUROPEAN UNION EC DIRECTIVES Directive 89 336 CEE Directive 73 23 CEE These Lab Water Systems are designed and manufactured in application of the following European Council directives 89 336 CEE relating to Electromagnetic compatibility 3 23 CEE relating to electrical equipment designed for use within certain voltage limits Standards to which conformity is declared as applicable are the following EN 55022 Classe B 1998 limits and method of radio disturbance characteristics of information technology equipment EN 50082 1 1997 Electromagnetic compatibility generic immunity standard EN 61000 3 2 1995 7 Al and 2 1998 2000 Electromagnetic compatibility EMC Part 3 2 limits Limits for harmonic current emissions equipment input current up to and including 16A per phase EN 61000 3 3 1995 Electromagnetic compatibility EMC Part 3 limits Section 3 limitation of voltage fluctuation and flicker in low voltage supply systems for equipment with rated current inferior or equal 6A EN 61010 1 1993 A2 1995 Safety requirements for electrical equipment for measurement control and laboratory use IT IS IMPORTANT
77. er quality Follow the steps below to replace the Quantum Cartridge Removing the Quantum Cartridge from the Milli Q Make sure the Milli Q is in STANDBY mode See Section 5 1 for more information if necessary Since the Q Gard was just replaced see Section 6 2 it is not necessary to release the residual water pressure in STANDBY mode Open the top and bottom latches of the door on the front of the Milli Q system cabinet Fully open the door Remove the Quantum Cartridge from the Milli Q Installing a new Quantum Cartridge Remove the Quantum Cartridge from its shipping box Confirm that you have the desired type of Quantum Cartridge by viewing the label on the Quantum Cartridge Remove the 2 plastic covers on the ports of the Quantum Cartridge There should be a black rubber O ring in each port Make sure these are pushed firmly in place Wet the Quantum Cartridge O rings with water It is preferable to wet them with Ultrapure Water DO NOT WET THE O RINGS WITH A LUBRICANT SUCH AS OIL OR SILICON GREASE Push the Quantum firmly into place Both the top and bottom ports of the Quantum Cartridge have to be fully seated Close the door Make sure that both the top latch and the bottom latch of the door A memon are fully closed Each latch should click when it is fully closed The Quantum Cartridge is now installed You now need to perform
78. i Q has a supply of feedwater that can be delivered to the Milli Q 54 Message and System Status REBOOT SYSTEM You can continue to use the Milli Q EXCHANGE UV EXCHANGE A10 UV You may continue to use the Milli Q SYSTEM ERROR 1 You may continue to use the Milli Q SYSTEM ERROR 2 You may continue to use the Milli Q SYSTEM ERROR 3 You may use the Milli Q if the temperature reading is incorrect SYSTEM ERROR 4 The ionic levels in the Milli Q Product Water are elevated and it is the decision of the Milli Q user whether to use the water or not SYSTEM ERROR 5 You may continue to use the Milli Q SYSTEM ERROR 7 The POU Dispenser will not dispense water You will not be able to dispense water Milli Q Synthesis A10 only The 10 has tried for gt 15 minutes to process value but was not successful The UV lamp has been installed for 365 days Milli Q Synthesis ATO only The 10 has a small UV Lamp inside lt has been installed for 365 calendar days The Motor Voltage is gt 49 VDC too high The measured temperature is O C The measured temperature is gt 45 C resistivity value between 3 5 The measured 29 9C is 2 5 MQ cm The measured resistivity is too high gt 65 5 The displayed resistivity may not show any higher than 18 2 MQ cm The voltage being sent to the UV Ballast Power Supply on the Intertace PC Board is lt 5
79. i Q and needs to be ordered separately The computer end of this cable has a 9 pin connection It installs into either the COMI or Port of your computer How TO DO IT Connect the Computer Cable COMPCBLO1 between the Water System and the Computer The installation instructions are not in this manual The installation instructions come with the Computer Cable Using Windows 95 or 98 click on START then PROGRAMS then ACCESSORIES then HYPERTERMINAL deua Accessories Communications E Adobe Acrobat gt gj Fax HyperT erminal AutoSketch gt 3 Games File Edit Go Favorites gt gt New Office Document DragAndZip gt Multimedia 5 Internet Explorer System Tools 8 Y 222 Open lice Document C Lotus Applications Calculator Programs Favorites McAfee VirusScan MGA PowerDesk gt Online Services Character Map gt 9 Dial Up Networking 34 Direct Cable Connection StartUp HyperTerminal A Documents gt Internet Explorer 3 Imaging Ek Q9 Microsoft Binder Notepad Settings 25 Microsoft Excel Pant J EE Microsoft NetMeeting 7 Phone Dialer amp Microsoft Photo Editor Synchronize amp s Microsoft PowerPoint 2 WordPad Wu an Microsoft Word Y an e MCI il h fizer TT 7 1 ht plizer J E eras Espe
80. ing absolutely trace levels of ions is critical The Millipore Catalogue Number for a Quantum IX is QTUMOOOIX See Section 8 1 for more information The Quantum EX contains ion exchange resin and synthetic carbon These purification media are used when the Milli Q Product Water needs to have both trace levels of ions and trace levels of organic species The Millipore Catalogue Number for a Quantum EX is QTUMOOOEX See Section 8 1 for more information The Quantum VX contains media that removes Volatile Organic Carbon species and maintains trace levels of ions The Millipore Catalogue Number for a Quantum VX is QTUMOOOVX See Section 8 1 for more information WHEN DO CHANGE THE QUANTUM ULTRAPURE CARTRIDGE It is recommended to change the Quantum Ultrapure Cartridge when the Q Gard Purification Pack is changed See When do I change the Q Gard Purification Pack see the section above for more information PRODUCT INFORMATION PYROGARD 5000 UF CARTRIDGE Pyrogard 5000 UF Cartridge called UF Cartridge in the remainder of this manual is used to remove any Pyrogens or Endotoxins in the Milli Q Product Water The UF Cartridge will also remove bacteria from the water passing through it The maintenance of the UF Cartridge involves sanitising and cleaning it every 4 weeks with Sodium Hydroxide The Sanitisation of the UF Cartridge is described in the Maintenance Chapter of this manual The UF Cartridge has a Reject Water Stre
81. ing connection Make sure your Milli Q System Power Switch is in the OFF position The Power Switch is off when the O position is selected Plug the Power Cord into the Milli Q It plugs in next to the Power Switch Plug the other end of the Power Cord into an appropriate source of electrical power i e wall outlet 4 3 INSTALLATION OF THE Q GARD Make sure the electrical power is off to the Milli Q system The Q Gard is installed on the Milli Q front right side Locate the white Q Gard Pack Adapter lid Look below the lid and locate the 2 yellow plastic inserts Pull them out and remove them Remove the Q Gard from its shipping box Verity the Millipore Catalogue Number by looking at the sticker on top of the Q Gard sticker should be blue Remove the plastic covers on the 2 ports of the Q Gard Pack Look inside the ports to locate the black rubber O rings Make sure these are pushed in so they are firmly in place Wet the Q Gard O rings with water lt is preferable to wet them with ultrapure water DO NOT WET THE O RINGS WITH A LUBRICANT SUCH AS OIL OR SILICON GREASE Locate the small protruding piece of plastic near the bottom of the Q Gard Push this into the small hole in the Milli Q Cabinet This will aid in holding the Q Gard Pack upright Push the Q Gard Pack onto the Pack Adapter The Q Gard Pack rubber O rings will be making a water tight sea
82. installed during installation Please note that the Pressure Relief Valve is factory installed inside all Milli Q systems and only the tubing needs to be attached during installation PUMP The pump is used to bring water into the Milli Q and then to send it through the various components such as the Q Gard Purification Pack and the Quantum Ultrapure Cartridge Q GARD The Q Gard Purification Pack is used to remove ions and organic molecules from the feedwater The Q Gard is a consumable device A consumable device is something that is periodically changed out for a new one during the maintenance of the Water System WHAT ARE THE DIFFERENT TYPES OF Q GARDS The Q Gard 1 is used when the feedwater comes from RO distillation or Electrodeionisation EDI An example of RO or EDI feedwater is the water coming from either a Millipore RiOs or Water Purification System This type of teedwater typically has some ions but contains little organic particulate and colloidal contamination The Millipore Catalogue Number for a Q Gard 1 is QGARDOOR1 See Section 8 1 for more information The Q Gard 2 is used whenever the feedwater comes from a source other than those mentioned above example of feedwater requiring a Q Gard 2 would be Service Deionised Water this is the process of deionising water by connecting bottles of ion exchange directly to tap water and deionising the tap water Deionised Water produced by multiple regeneration ion exch
83. ith Remote POU Dispenser A TROUBLESHOOTING THE PROBLEM IS LOW RESISTIVITY OF THE PRODUCT WATER CAUSE REMEDY lon Exchange Capacity of Q Gard Pack and Quantum e Replace Q Gard and Quantum at the same time Cartridge exhausted used up Non Temperature Compensated Resistivity values e Check the Temperature Compensated Resistivity shown and water temperature is gt 25 C Value See Section 4 13 Conductivity values uS cm displayed Nothing wrong Change to a Display to check values See Section 4 1 Something other than a Q Gard Pack is installed by Check Number of installed Pack See mistake Section 8 1 lon Exchange Resin was fouled by high levels of e Switch to a feedwater such as RO or Elix Colloidal Species Feedwater Occurs with Deionised Feedwater i e Service Deionised Feedwater Problem with internal component Contact Millipore UF Cartridge is dirty Perform a SAN CYCLE Sanitisation and Cleaning of the UF Cartridge See Section 6 5 for more information UF Cartridge is slightly dirty e Perform an AIR PURGE See Section 6 11 for more information Resistivity is low immediately following the completion e Perform an AIR PURGE and then go to PRODUCT of a Sanitisation and Cleaning of the UF mode for several minutes to rinse the UF Cartridge Repeat the AIR PURGE if necessary 8 TROUBLESHOOTING THE PROBLEM IS THERE IS NO POWER TO THE MiLLI Q SYSTEM CAU
84. l lt is important that the Q Gard is pushed fully The notch on the end of the metal rod on the Pack Adapter should come through the hole on the Q Gard Pack Locate the metal clip that is attached to the Pack Adapter with a piece of filament wire Push the metal clip onto the notch of the metal rod see the step above The top of the Metal clip should bend towards you This will allow you to easily remove it when the Q Gard is replaced later The Q Gard is now installed 2 INSTALLATION FEEDWATER TUBING CONNECTION 250 V UF REJECT TUBING CONNECTION AND PRESSURE RELIEF TUBING CONNECTION 250 V 3 8 Milli Q Synthesis Synthesis 28 INSTALLATION OF THE Q GARD PACK INSTALLATION Milli Q Synthesis Synthesis ATO 29 INSTALLATION 4 4 TURNING ON THE SYSTEM POWER Q Turn on the Milli Q system electrical power The Power Switch is located on the rear of the Milli Q system cabinet The is the on position of the Power Switch Q Make sure the POU Dispenser Trigger is in the upright position When the system power is on but the Quantum Cartridge is not installed the LCD should look like NOTE display messages may be in english on your Milli Q system go to chapter 4 11 to change your display language SYNTHESIS V3 03 gt PRE OPERATE SR NO F1PN64537 RECIRCULATION System type software version and serial number displayed for PRE OPERATE about 10 seconds CARTR
85. length of the Footswitch Cable is 5 meters You will use about 0 3 meters of the Footswitch Cable inside the Milli Q PRINTER OR COMPUTER CABLE The Millipore Catalogue Number for the Printer Cable is PRNTCBLO1 Its length is 2 79 meters The Millipore Catalogue Number for the Computer Cable is COMPCBLO1 lis length is 1 65 meters You will use about meters of either cable for its connection inside the Milli Q cabinet REMOTE DISPLAY WITH KEYPAD The Millipore Catalogue Number for a Remote Display is ZMQSRMDS1 The Remote Display allows you to view the LCD and to use the Keypad Buttons remotely The dimensions of the Remote Display are length 204 mm height 112 mm and depth 48 mm lts weight is 91958 The Remote Display comes with a meter cable that plugs into Milli Q System inside You will use about O 6 meters of the cable inside the Milli Q The Remote Display can be wall mounted There are 2 Stainless Steel Brackets that are attached to either side of the Remote Display These brackets can be fastened the wall The Hardware necessary to attach these brackets to a wall i e screws bolts does not come with the Remote Display The instructions for installing the Remote Display are inside its shipping box The instructions for installing a Remote Display are not inside this manual Contact Millipore for these instructions if you would like to see them before obtaining the Remote Display EXPLORE DATA SOFTWARE
86. li Q System with a Front Arm comes with a POU Dispenser 2 A Milli Q System without a Front Arm does not come with a POU Dispenser A Remote POU Dispenser would be needed Milli Q Synthesis Synthesis ATO Gradient and Gradient A10 Systems have a UV Lamp inside Milli Q Synthesis Synthesis ATO Biocel Biocel Systems have a UF inside 84 APPENDIXES Chapter 9 APPENDIXES APPENDIX 1 HOW TO REPLACE THE MAIN POWER FUSE Follow the steps below to replace the main Power Fuse Place the Milli Q into STANDBY mode if it is in PRE OPERATE or PRODUCT mode See Section 5 1 for more information 1 Turn off the Milli Q Power Switch It is located on the back of the Milli Q cabinet just above the location where the Power Cord is plugged into the Milli Q D Unplug the Power Cord from the Milli Q System 3 Obtain the correct replacement fuse There is a spare fuse located in the fuse holder See step It is very important to use the correctly sized replacement fuse Failure to use the correct replacement fuse could result in system damage or an electrical fire System Voltage Main Power Fuse Size 120 VAC 10 2 Amp SLO BLO 250 VAC 5 mm x 20 mm 230 VAC 10 1 Amp SLO BLO 250 VAC 5 mm x 20 mm 1 Use a small flathead screwdriver to open the Fuse Holder This is located immediately above the point where the Power Cord plugs in 2 Remove the entire fuse holder Replace the blown fuse you can check the fuse for ele
87. m the feedwater side of the UF Cartridge Membrane This may help when the Product Water resistivity is low Follow the steps below to perform an AIR PURGE a IF the Milli Q is in STANDBY mode then go to PRE OPERATE mode It is not possible to access the AIR PURGE mode from STANDBY mode Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 ES Press MENU for about 2 seconds Q You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the LCD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button for about 2 seconds This will place the Milli Q into STANDBY mode Then press the STANDBY OPERATE Keypad Button again The Milli Q will now be in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Service Software Press the MENU Keypad Button 6 times 7 times for a Milli Q Synthesis A10 Stop when you see the AIR PURGE display PRESET VOLUME me rn FLOW MEASURE Press MENU pe eee ree TN 5 each time SERVICE UF AIR PURGE 5 mn Wait about seconds 5 minute AIR PURGE will start automatically 23 MAINTENANCE The LCD will show a message OPEN THE VALVE alternating with AIR PURGE 5 mn SERVICE UF SERVICE UF lt
88. n shaft and small head locate the small hole on the top part of the Quantum Cartridge Door 22 INSTALLATION Gently insert the screwdriver into the Quantum Cartridge This will open a small vent that will expel any air in the Quantum Cartridge Be very careful when pushing the tip of the screwdriver into the VAN ATTENTION Vent Hole of the Quantum Cartridge The Vent Hole only needs to be opened a very small amount lf all of the air does not expel out do not worry You can repeat this step later after more water has flowed through the Milli Q Remember to have the Milli Q in STANDBY or PRE OPERATE mode while you are expelling air out of the Quantum Cartridge 4 8 HYDRATING THE SYSTEM At this time the MilliPak is not installed Barbed Fitting and Tygon Tubing should still be attached to end of the POU Dispenser leave the Milli Q in PRE OPERATE mode overnight for several hours This will aid in rinsing off the purification media inside the Q Gard Pack and the Quantum Cartridge Do not leave the Milli Q in STANDBY mode The next morning Bring the POU Dispenser Trigger forward to put the Milli Q into PRODUCT mode Allow about 10 to 15 litres about 7 to 10 minutes of water to be dispensed trom the Milli Q Bring the POU Dispenser Trigger upright The Milli Q will finsih dispensing water The Milli Q will continue to operate for 90 seconds after which it will go into PRE OPERATE mode
89. ocate the black rubber O rings Make sure these are pushed in so they are firmly in place Wet the Q Gard O rings with water It is preferable to wet them with Ultrapure Water DO NOT WET THE O RINGS WITH A LUBRICANT SUCH AS OIL OR SILICON GREASE locate the small protruding piece of plastic near the bottom of the Q Gard Push this into the small hole in the Milli Q Cabinet This will aid in holding the Q Gard Pack upright Push the Q Gard Pack onto the Pack Adapter The Q Gard rubber O rings will be making a water tight seal It is important that Q Gard is pushed in fully The notch on the end of the metal rod on the Pack Adapter should come through the hole on the Q Gard Pack locate the metal clip that is attached to the Pack Adapter with a piece of filament wire Push the metal clip onto the notch of the metal rod see the step above The top of the metal clip should bend towards you This will allow you to easily remove it when the Q Gard is replaced later The Q Gard is now installed Since the Quantum Cartridge is replaced whenever a Q Gard Pack is replaced roceed to Section 6 3 How to replace the Quantum Cartridge INSTALLATION OF THE Q GARD PACK MAINTENANCE Milli Q Synthesis Synthesis ATO 59 MAINTENANCE 6 3 HOW TO REPLACE THE QUANTUM CARTRIDGE The Quantum Cartridge is replaced whenever the Q Gard Pack is replaced This is important for maintaining optimum wat
90. ode Move the POU Dispenser Trigger forward and then back up This will place the Milli Q into PRODUCT mode but water will not be dispensed at the moment A very small amount of water i e 5 ml may be dispensed out green LED on the side of the POU Dispenser will begin to blinking will stop blinking when the Product Water Resistivity compensated to 25 C is greater than the Resistivity Setpoint and less than the TOC setpoint 10 system only Normally the Resistivity Setpoint is 16 0 MQ cm It is recommended but not necessary to wait until the green LED stops blinking on the POU Dispenser Q Press MENU for about 2 seconds The LCD should change as shown below PRE OPERATE PRESET VOLUME 0 00 Press MENU for about 2 seconds Use the Keypad Arrow Keys MEASURE or CLEANING to set the volume of water you want to dispense from the Milli Q 18 2MQ cm 25 C PRESET VOLUME 6 50 6 50 L is the desired volume to be dispensed Use the Arrow Keypad Buttons to change the PRE SET VOLUME value 50 USING THE MiLLI Q Press the OPERATE STANDBY Keypad Button to validate your volume selection The Milli Q will now go to PRE OPERATE mode PRESET VOLUME 6 50 CLEANING OPERATE STANDBY Move the POU Dispenser Trigger forward The Milli Q will go from PRE OPERATE mode to PRODUCT mode The LCD will show lower right corner the amount of water being dispensed 021 co
91. ollow these steps below to perform an ATO CLEANING a If the Milli Q is in STANDBY mode then press the OPERATE STANDBY Keypad Button for about 2 seconds This will change the Milli Q from STANDBY mode to PRE OPERATE mode See the drawing below for more information STANDBY PRE OPERATE CLEANING Press for about 2 seconds Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 E Press MENU for about 2 seconds Q You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the LCD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button about 2 seconds This will place the Milli Q STANDBY mode Then press the STANDBY OPERATE Keypad Button again The Milli Q will now be in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Service Software Press the MENU Keypad Button 5 times Stop when you see the SERVICE ATO ATO CLEANING display VOLUME SERVICE PRINTER et AGE SERVICE CALIB FLOW MEASURE Press MENU SERVICE 10 each time A10 CLEANING 7 3 MAINTENANCE WAIT Do not press the Keypad The A1O CLEANING mode will start automatically after 5 seconds 60 minute timer will be shown SERVICE 10 SERVICE 10 SERVICE 10 A10 CLEANING A10 CLEANING 60 ATO CLEA
92. ompounds are desired or with Life Science Applications where Endocrine Disrupter Analysis is being done The Non Sterile MilliPak Express 20 has a Millipore Catalogue Number of 2001 See Section 8 1 for more information WHEN DO CHANGE THE MiLLIPAK The MilliPak is changed when the Q Gard Purification Pack and the Quantum Ultrapure Cartridge are changed However it may be necessary to change the MilliPak if it becomes clogged with particles or bacteria and reduces the flowrate of Milli Q Product Water PRODUCT INFORMATION Q GARD QUANTUM MILLIPAK Milli Q Synthesis Synthesis 1 PRODUCT INFORMATION A10 TOC MONITOR WHAT DOES THE A10 po The ATO TOC Monitor called ATO in this manual is used to measure the TOC of the Milli Q Product Water The A10 is located inside the Milli Q System Cabinet Any Milli Q system with an A10 inside will have A10 on the end of the name of the Milli Q i e Milli Q Synthesis A10 vs Milli Q Synthesis An 10 TOC measurement is initiated every time the Milli Q is brought from PRE OPERATE to PRODUCT mode when the POU Dispenser Trigger is brought forward single TOC Measurement will take approximately 5 minutes lt is possible to have TOC analysis time of either 9 12 minutes when the TOC levels are high The ATO will continuously perform TOC measurements while the Milli Q is in PRODUCT mode The ATO will perform a TOC measurement once per hour while the Milli Q
93. pose the feedwater to a Milli Q is 15 Milli Q Resistivity Sensor will measure a Resistivity Value of 31 756 MQ cm a Conductivity of 0 032 uS cm This is the actual Resistivity of the Milli Q Product Water at The Milli Q will perform a temperature compensation for the Resistivity measurement It will be compensated to a measurement that would be seen at 25 C When a Resistivity measurement of 31 756 MQ cm 15 C is temperature compensated to a measurement at 25 C then the Milli Q will display 18 2 25 C Temperature compensation is a way of standardising Resistivity or Conductivity to measurements that would be seen if the water temperature was 25 C WHY USE NON TEMPERATURE COMPENSATED VALUES USP 24 Water Quality Standards require a non temperature compensated conductivity value to be measured and reported Follow the steps below to display non temperature compensated Resistivity or Conductivity values Choose whether you want to display Resistivity MQ cm or Conductivity uS cm See Section 4 12 in this Chapter for information on how to change between these types of measurement units Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 E Press MENU for about 2 seconds You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on th
94. pressed As an example suppose you want to change the Milli Q from STANDBY mode to PRE OPERATE mode This is done by pressing the OPERATE STANDBY Keypad button for about two seconds There are four Keypad buttons These are labelled as OPERATE STANDBY MEASURE CLEANING and MENU 0 0 POWER STANDBY SERVICE SERVICE ALARM OPERATE STANDBY MEASURE CLEANING OPERATE STANDBY MEASURE CLEANING MENU lt lt gt gt See the drawing above for their placement The LCD is a backlit dual line 16 character display The LEDs are located to the right of the LCD see above The POWER LED is green This is lit when the Water System microprocessor has electrical power The SERVICE LED is yellow This will flash when a service type of LCD message is displayed i e EXCH CARTRIDGES is shown meaning to change the cartridges in the system The ALARM LED is red This will flash when an alarm condition is indicated on the LCD i e PAK NOT IN PLACE meaning a purification pack is not fully in place or is absent INTRODUCTION COMMONLY USED ABBREVIATIONS IN THIS MANUAL This manual will use abbreviations for text that is commonly repeated i e Liquid Crystal Display is abbreviated as LCD The table below shows a list of the abbreviations used in this manual microSiemens per centimeter a measurement unit describing the electrical conductivity of water a Millipore device which measures TOC Ultrapure Water American Socie
95. rade Water The specifications ASTM Reagent Grade Water are shown below Note that the Water Quality Specifications for a Milli Q Synthesis or Milli Q Synthesis A10 are listed in the section just above From Standard Specitication tor Reagent Water Designation D 1193 99 American Society For Testing Materials Parameter Value mmanemam e pH not specified The measurement of pH has been eliminated for this standard because this grade of water does not contain constituents in sufficient quantity to alter pH PRODUCT INFORMATION 2 2 SCHEMATIC OF MAIN COMPONENTS The water flow through a Milli Q Synthesis Water Purification System is shown here in a flow diagram A description of each item is in the next section below 5 nuum O 1 RECIRCULATED WATER PATH MILLI Q PRODUCT FEEDWATER WATER A P E F 7 M PRESSURE RELIEF UF DRAIN The water flow through a Milli Q Synthesis A10 is shown here in a flow diagram gt ar ae 1 RECIRCULATED WATER PATH MILLI Q 1 PRODUCT FEEDWATER WATER A Pa 8 p E f v C 10 10 Identification of lettered items in the flow schematic above Inlet Solenoid UV Lamp and Resistivity Housing Sensor Quantum Electric 2 way Ultrapure Valve Cartridge Pyrogard MilliPak Purification 5
96. rating Temperature air temp Between 5 C and 25 C Relative Humidity Between 20 and 80 without condensation Operating Altitude Less than 2000 Meters OTHER REQUIREMENTS Reservoir is the feedwater source If you are using a reservoir as the feedwater source then you will need a ball valve on the reservoir This ball valve is normally supplied on the standard Millipore 30 L or L 100 Reservoirs The end of the ball valve should terminate with a fitting that accepts 8 mm tubing This fitting is not supplied on the standard Millipore L or L 1001 Reservoirs You can order a fitting from Millipore with a 1 4 inch NPTM connection on one end and an 8 mm tubing insert on the other Contact Millipore if your reservoir has another thread size on the port you want to use for the feedwater connection to the Milli Q PRE INSTALLATION 3 5 UNPACKING THE MiLLI Q BOX WHAT S INSIDE Open the Milli Q Shipping Box Use the checklist and illustrations below to make sure all items were shipped and are accounted for lt is highly suggested to become familiar with the items that are shipped in the Accessories Bag since these will be used in the Installation Section of this manual Check the box Q if item is present Contact Millipore if an item is missing Do you have Q Milli Q Water Puritication System Electrical Power Cord Inside the Accessories Bag Black Tubing 8 mm OD about 5 meters in
97. renced above has an O ring on its thread You will not need to use Teflon Tape on this fitting Simply screw this connector into place Measure the distance between the Reservoir and back of the Milli Q Allow some extra distance so the Milli Q could be rotated or moved without stretching the tubing Cut an appropriate sized length of the black 8 mm OD tubing The remainder of the length of the black 8 mm OD tubing will be used for the UF Reject tubing Install one end of this tubing to the Reservoir Push one end of the tubing into the collar of the fitting until it will go no further Pull on it slightly to insure it is fully seated inside the collar FEEDWATER IS FROM A PRESSURISED SOURCE SUCH AS A PIPE A LOOP Get the roll of Tetlon Tape and the 8 mm tubing plus Screen Filter from the Accessories Bag Make sure that the pipe end is a 1 2 inch NPTM connection If this connection is not ready then you will need to obtain the proper fittings to be able to attach the fittings trom the Milli Q Accessories Bag Wind about 3 to 4 turns of Teflon Tape on the end of the pipe connection The tape should be wound in a clockwise direction same direction the fittings will be turned Screw the Screen Filter the end of the pipe You may want to remove the attached 8 mm tubing to facilitate the turning of the Screen Filter Assembly Measure the distance needed for the Feedwater Tubing This is the distance between the Screen Filter
98. rigger back to its upright position Escape the Customer Service Software by pressing the MENU Keypad Button for about 2 seconds You should be back to PRE OPERATE mode SERVICE CALIB FLOW 1 151 1 mn Press MENU for about 2 seconds CLEANING You have finished calibrating the Product Water Flowrate from the Milli Q See the MAINTENANCE Chapter see Chapter 6 of this manual to see when to perform a Flow Calibration 37 INSTALLATION 4 11 HOW TO CHANGE THE DISPLAYED LANGUAGE It is possible to have different languages displayed These include English French Spanish German Italian Japanese and Portuguese you change the displayed language remember that the Customer Service Software remains in English Follow the steps below to change the displayed language Q Press the MENU Keypad button for about 2 seconds The LCD will change as shown here PRE OPERATE PRESET VOLUME 0 00 CLEANING Press MENU for about 2 seconds Q You have entered the Customer Service Software of the Milli Q If you do not see this display then turn off then on the system power When the LCD shows PRE OPERATE and RECIRCULATION press the STANDBY OPERATE Keypad Button for about 2 seconds This will place the Milli Q STANDBY mode Then press the STANDBY OPERATE Keypad Button again The Milli Q will now in PRE OPERATE mode Press the MENU Keypad Button again for 2 seconds to enter the Customer Servic
99. rs fy Windows Messaging a Double Click on the HYPERTRM EXE icon Q Enter a name example MQ and then choose an icon You can use this later for tuture downloads Elx HyperTerminal File Edit iew Call Transfer Help New Connection HyperTerminal Ele Edit Call Transfer Help Enter a name and choose an icon for the cor Enter details for the phone number tha Name County code Icon Area code nem Ex 3 Choose Direct to COM 1 COM 2 then click on OK Forthe COM properties change the settings to be 89 APPENDIXES COM1 Properties 2 Ea Bits Per Second 9600 Bits per second 3600 Data bits 8 i Data bits 8 Pa rity none Parity Stop bits mH Sto p bits 1 Flow control None R F OW nt rol n n e Advanced Restore Defaults Click OK Open the TRANSFER menu and click on CAPTURE TEXT Choose a tile name for the data to downloaded By default the data will be saved in the directory C ProgramFiles Accessories Hyperterminal txt Now click on START Elixdata txt is an example file Ele Edit View Cal name shown below Ole sia 5 Send File ecerve File Capture Text Folder C Program Files amp ccessoriessHyperT erminal Capture Text File s Accessories HyperT eminalsE lisdata tt Browse Send Text
100. s Quantum VX Cartridge Quantum ICP Cartridge QTUMOOICP 1 box MilliPak not included used for sub ppt level elemental analysis Quantum Cartridge with Non sterile QTUMMPEIX Quantum Cartridge 1 Non sterile MilliPak Express 20 MilliPak Express 20 per box Quantum EX Cartridge with Non sterile QTUMMPEEX Quantum Cartridge 1 Non sterile MilliPak Express 20 MilliPak Express 20 per box MilliPak 40 Sterile MPGLOASK2 2 box used for Science Applications MilliPak 20 Express Non sterile 2001 l box see Section 2 3 for more information A10 UV Lamp ZFATOUVOI 1 box UV Lamp ZMQUVLPO 1 1 box gloves included 83 ORDERING INFORMATION 8 2 CATALOGUE NUMBERS FOR ACCESSORIES See Section 3 2 for information about the various accessories that can be used with a Milli Q Wall Mounting Bracket SYSTFIXO 1 Pressure Regulator ZFMQOOOPR Remote POU Dispenser see below also ZMQSPOUR 1 Installation Kit for Remote POU Dispenser ZMQSPOUOl Remote Display ZMQSRMDS 1 Computer Cable 1 Explore Data Software SOFTOOOA A10 TOC Monitor Upgrade Kit ZMQUPGA 1 8 3 CATALOGUE NUMBERS FOR ALL MILLI QS _ 1 5 230 5 6 120 VAC System 7 100 VAC System T 2 with A O without A F with UF O without UF E Milli Q Element S with Front Arm V with UV Lamp O without UV O O P without Front Arm NOTE 1 Mil
101. s ZMQSPOU01 The installation instructions for the Remote POU Dispenser are not included with this manual These instructions are included with the Remote POU Dispenser Please contact Millipore if you would like a copy of these instructions ahead of time The use of the Remote POU Dispenser is exactly the same as one mounted on the Front of the Milli Q Cabinet It is suggested to recalibrate the flowrate from the Milli Q if you are using the Remote POU Dispenser more often than the Front POU Dispenser The flowrate from the Remote POU Dispenser may be slightly lower than from the Front POU Dispenser 92 APPENDIXES APPENDIX 6 COMP MODE 1 AND COMP MODE 2 Section 4 13 in this manual explains how to display Non Temperature Compensated Resistivity or Non Temperature Compensated Conductivity Displays When you are using the Milli Q Software to make this change you may notice the terms COMP MODE 1 COMP MODE 2 and OFF What do these mean 2 OFF means that the Temperature Compensation is off The displayed Resistivity or Conductivity will not be temperature compensated The temperature of the water will be shown at the same time as the non temperature compensated Resistivity or Conductivity value COMP MODE 1 is the normal setting This setting will display Resistivity or Conductivity values that are temperature compensated to 25 C The values are normalised The Software of the Milli Q eliminates small fluctuations of temperature compensate
102. sharp click noise This is the opening of the Inlet Solenoid Valve Q The LCD will change and will look like PRE OPERATE PRODUCT STANDBY OPEN THE VALVE AIR PURGE 5 mn gt CLOSE THE VALVE let the AIR PURGE continue for its 5 minute duration It will count down to O minutes 5 4 mn Pressurised Feedwater Only Check the Pressure Gauge on the Pressure Regulator While water is flowing through it the Pressure Gauge should show 0 3 bar If it is not set fo 0 3 bar then turn the round handle on the Pressure Regulator clockwise until the pressure gauge on the regulator shows O 3 bar Check this again when water is flowing through the Pressure Regulator The setting of the Pressure Regulator should not exceed 0 3 bar feedwater pressure reaching the Milli Q in PRODUCT mode should not exceed 0 3 bar The Pressure Regulator should only be set while water is flowing through it It is perfectly normal to see an increase in the Pressure Regulator setting while water is not flowing through it i e STANDBY or PRE OPERATE mode a The Milli Q will now go to STANDBY mode and will remind you to close the POU Dispenser Valve Move the POU Dispenser Trigger back its upright position The Milli Q will now go to PRE OPERATE mode STANDBY PRE OPERATE CLOSE THE VALVE MAINTENANCE o Milli Q Synthesis ATO only When you Close Valve the Milli Q will go to PRE OPERAT
103. t Point Of Use Dispenser These are called Production or Armless Milli Q Systems These Milli Q Systems always begin with ZMQP instead of ZMQS When a Production Milli Q is ordered you ordered Millipore Catalogue Number ZMQP for example the Milli Q arrives in a box without a Front Arm and without a Front Point Of Use Dispenser It is necessary to have a Remote Point Of Use Dispenser with these types of Milli Qs Section 3 3 of this manual has more information regarding the Remote Point Of Use Dispenser It may be desired to have Remote Display with the Production Milli Q System example of when this would be needed is when the Milli Q System is being mounted underneath Lab Bench In this instance the Remote Display and Remote Point Of Use Dispenser could be mounted on top of the Lab Bench When you have a Production type of Milli Q System use the same Pre Installation Checklist on the previous page Additionally you should review the items below also Do you have a Remote Point Of Use Dispenser this item is not part of a ZMQP Millipore Catalogue Number Do you have a Remote Display this item is not part of a ZMGP Millipore Catalogue Number Will the Milli Q System Cabinet and the Remote POU Dispenser be located within 2 5 meters of each other D D Will the Milli Q System Cabinet and the Remote Display be located within 2 4 meters of each other PRE INSTALLATION 3 3 OPTIONAL EQUIPMENT YOU
104. the pipe and the Milli Q 2 5 the water system feeding the pipe fully operational 2 Does the pipe have a valve ending with a 1 2 inch NPTM connection If not do you have a fitting or connection that will attach to the pipe and will end in a 1 2 inch NPTM connection ls there a way to shut off water from the pipe to the Milli Q 2 If not did you order a ball valve from Millipore to install on the Feedwater Tubing Are you mounting the Milli Q on a wall A wall mounting bracket may be needed in specific conditions a Will the wall support the weight of the Milli Q plus full reservoir 5 the Milli Q accessible at this height viewing the LCD using the keypad Did you include space on the right side of the Milli Q to remove and replace the Q Gard 2 Did you want a location so as to dispense water over a sink Is the Milli Q located within 2 5 meters of a drain for the UF Reject tubing Is the Milli Q located within 2 5 meters of a drain for the Feedwater Pressure Relief Valve tubing 2 Are the room environmental conditions adequate humidity temperature 9 If you are going to connect a printer or computer to the Milli Q later did you leave room for this 2 If you are using a footswitch accessory to control the Milli Q did you leave room for this 2 PRE INSTALLATION 3 2 PRE INSTALLATION CHECKLIST ARMLESS MiLLI Q Milli Q Systems can be ordered from Millipore without the Front Arm and without the Fron
105. to dispense water a maximum distance of 2 5 meters away from the Milli Q Remote POU Dispenser is rested on a moveable arm that allows 1809 rotation The Millipore Catalogue Number for a Remote POU Dispenser plus arm and weighted base is ZMQSPOUR1 It is also necessary to order an installation kit with the Remote POU Dispenser This Installation Kit has a Millipore Catalogue Number 2 05 0001 The Remote POU Dispenser can be either wall mounted or set on a benchtop The Installation Instructions for the Remote POU Dispenser are included with it PRE INSTALLATION REMOTE POINT OF USE DISPENSER USED ON A PRODUCTION TYPE MiLLI Q A Production type Milli Q System needs to have a Remote Point Of Use Dispenser added to it Without one you would not be able to dispense water from the Milli Q All of the information in the above section Remote Point Of Use Dispenser applies to a Production type of Milli Q System You will not need to order the Installation Kit however The items in the Installation Kit are Factory installed on Production Milli Q Systems Do not order Installation Kit Catalogue Number ZMQSPOUO when VAN ATTENTION you have a Milli Q System beginning with a ZMQP Catalogue Number FOOTSWITCH The Millipore Catalogue Number for the Footswitch plus cable is ZMQSFTSO1 The Footswitch allows you a hands free operation where you could change the Milli Q from PRE OPERATE mode to PRODUCT mode The
106. ty for Testing and Materials Endotoxin Units per millilitre LPM Litre Per Minute millimeter mm NPT National Pipe Thread the type of thread used a fitting NPTF National Pipe Thread Female National Pipe Thread Male ow i oeo RO Reverse Osmosis U Ultrofilter Cartridge F INTRODUCTION 1 2 SAFETY INFORMATION Your Milli Q Water Purification System should be operated according to the instructions in this manual In particular the hydraulic and electrical specifications should be followed and met lt is important to use this equipment as specified in this manual using this equipment in a different manner may impair the safety precautions of the Water System THIS HAZARD symbol is used to refer to instructions in this manual that need to be done safely and carefully THIS ATTENTION symbol is used to refer to instructions in this manual that need to be done carefully INTRODUCTION 1 3 CONTACTING MILLIPORE TELEPHONE AUSTRALIA DENMARK ITALY SINGAPORE Tel 1 800 222 111 Tel 70 10 00 23 Vimodrone Milano Tel 65 842 1822 or 02 9888 8999 Fax 70 10 13 14 Tel 02 25 07 81 Fax 65 842 4988 Fax 02 9878 0788 EASTERN EUROPE C LS Fax 02 26 50 324 SPAIN AND PORTUGAL AUSTRIA AFRICA MIDDLE EAST Roma Tel 34 917 283 960 Tel 01 877 8926 AND GULF 06 Ee Fax 34 917 292 909 Fax 01 877 1654 Life Sciences Division ax 06 52 95 735 SWEDEN Tel 33 3 88 38 9536 JAPAN BALTIC COUNTRIES
107. unter shows the total volume being dispensed 0 02 liters at this time Allow the water to be dispensed You can cancel the dispensing of water by moving the POU Dispenser Trigger upright back to the PRE OPERATE position When the pre set total volume of water has been dispensed from the Milli Q the system will automatically go to STANDBY mode The LCD will prompt you to CLOSE THE VALVE Bring the POU Dispenser Trigger to the upright position The Milli Q will now be in PRE OPERATE mode 18 2 25 C STANDBY PRE OPERATE 6 501 gt CLOSE THE VALVE If you want to automatically dispense the same volume of water again then follow all of the steps above You will not need to change the selected volume It will remain the same from the prior selection USING THE MiLLI Q 5 6 HOW TO VIEW THE AGE OF THE CONSUMABLES The Milli Q Synthesis has 4 consumable items These include the Q Gard Pack the Quantum Cartridge MilliPak and the UV Lamp The Milli Q Synthesis ATO has 5 consumable items These include the ATO UV Lamp plus the Q Gard Pack the Quantum Cartridge MilliPak and the UV Lamp The age of these consumables can be viewed The age of a consumable is the number of calendar days that have passed since the consumable was installed The age is displayed as a number of days The number of days will increase by 1 every 24 hours The maximum recommended age of the Q Gard Quantum and MilliPak is 180 days The m
108. verification of your Milli Q system Contact Millipore for more information regarding resistivity and temperature measurement verification in accordance with USP 24 specifications POINT OF USE VALVE The Point Of Use POU Dispenser has a 2 way electric valve inside This valve is closed when the POU Dispenser Trigger is in the upright position This also places the Milli Q into PRE OPERATE mode after 90 seconds if you were using the Milli Q in PRODUCT mode When the POU Dispenser Trigger is pushed down the electric valve is powered This allows water to be dispensed out of the Milli Q System instead of being recirculated back fo the pump see tlow diagram PRODUCT INFORMATION MILLIPAK The MilliPak End Filter is a membrane based filter that removes all particles and bacteria with a size greater than O 22 um by a sieving mechanism All contaminants larger than the filter pore size are retained on its surface This essentially will block and retain any bacteria present in the water flowing through it WHAT TYPES OF MILLIPAK FILTERS ARE THERE There are 2 types of MilliPak Filters sometimes called the Final Filter The Sterile MilliPak 40 is generally used for some Life Science applications This has a Millipore Catalogue Number of MPGLO4SK2 See Section 8 1 for more information The Non Sterile MilliPak Express 20 is generally used for Analytical Science Applications including applications where trace levels of Volatile Organic C

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