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HLA Fusion Release Notes - Research v3_0
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1. Release Notes HLA Fusion Research 3 0 Bug Fixes e A customer got an error upgrading a database using a SQL login that does not have a sysadmin role A sysadmin account should be used to properly upgrade the database e When assigning two test lists which have the same sample ID with the same test assigned on the plate both samples did not remain on the plate INSTRUCTIONS Updating Databases from Prior Versions of HLA Fusion Research Upgrading a Prior Version of an HLA Fusion Research Database after a New Installation For users of previous versions of HLA Fusion Research 1 After you have followed the HLA Fusion Research Installation Guide to install version 3 0 of HLA Fusion Research open the Fusion Research Database Utility by double clicking the shortcut on your computer desktop 2 Choose the Upgrade prior versions of HLA Fusion Research database to 3 0 function from the Fusion Research Database Utility Select the database you want to update and specify a location in which you want to store a backup copy Click the Upgrade button Choose the Select Database function from the Fusion Research Database Utility oa fF amp Select the database you upgraded in step 3 and click the Set button Support for New and Old Nomenclature in HLA Fusion Research 3 0 Our goal is to provide our customers and users with greater flexibility through the nomenclature change migration period while keeping the HL
2. Release Notes HLA Fusion Research 3 0 e Users can now more easily select sessions and samples from those sessions when they are starting a new SBT analysis e The system has a new Specialty Report for exporting KIR data to import into the LIS e Users can now view the samples in the test list before assigning to the plate design e Users can now assign and un assign the samples to the plate e Users can now assign Test lists to the plate e Users can now search for the samples which already exist in the previously designed plate s or in the current plate e Users can now assign the same sample with same test type more than one time on the same plate that is the plate shall support replicates of samples of same test type e Users can now import a Luminex patient list on to the plate and assign tests to the samples Note A well can hold only one type of test e Users can now delete edit all the unassigned plates e Users can now choose to view and assign already assigned plates e Users can now assign plates multiple times in the runs e Users can now delete all runs other than the run currently processing e ForLABScreen custom and express runs on LABXPress users can now choose the run with or without aliquotion e Users can now view print the reagent volumes required for express and custom runs through the run monitor e The system now validates the reagent loading after the loading is completed e If the reagent
3. A Fusion Research software performance and simplicity in mind The following only applies to Micro SSP for use with E Gene products 1 The HLA Fusion Research 3 0 Database migration upgrade from prior OLI software database e g HLA Fusion Research 1 3 1 and earlier versions HLA Visual HLA Tools etc will handle the nomenclature update as follows a HLA Fusion Research 3 0 software will migrate the data as is from prior OLI software databases meaning the HLA Fusion Research software will not translate old allele names into new allele names during the migration process b HLA Fusion Research 3 0 software will upgrade as is the databases created using the HLA Fusion Research 1 2 0 1 2 1X 1 3 0 and 1 3 1 versions HLA Fusion Research software will not translate old allele names into new allele names during the upgrade process 2 The Sero file that is currently available through the One Lambda download site has been updated to include new alleles Users are required to download this file first before importing any catalog into the HLA Fusion Research version 3 0 software Additionally this file will be used for translation of alleles The software will not support Sero files created before January 2010 3 The Patient Import module only accepts alleles in the new format If a patient import list contains Cw alleles these will be changed to C 4 HLA Fusion Research 3 0 software will support the import of catalogs in both old and new all
4. SOFTWARE M ONE LAMBDA INC HELEASE NOTES HLA Fusion Research Version 3 0 FUSREPGRX For Research Use Only Not for use in diagnostic procedures DESIGNATED USERS All users of HLA Fusion Research Software This software applies to ConsenSys Micro SSP for use with E Gene KIR Genotyping and Quantiplex RELEASE CONTENTS The HLA Fusion Research 3 0 package includes the following items 1 HLA Fusion Research 3 0 CD 2 HLA Fusion Research 3 0 User Manual 3 HLA Fusion Research 3 0 Installation Guide 4 HLA Fusion Research 3 0 Release Notes 5 HLA Fusion Research 3 0 Database Utility User Manual WHAT HAS CHANGED The following changes were made to HLA Fusion Research Software since version 2 0 and its related Service Packs Enhancements e Users can now select a default Home Page to start with when they log in to HLA Fusion e The system now provides A1 B2 A1B and A2B blood type choices on the patient form e The system has additional tutorial and Show Me features in the online help e Users can now reconfigure any HLA Fusion database to increase the maximum database size e Users can now merge HLA Fusion amp HLA Fusion Research audit log databases e Users can now include more lab information in custom reports e Titles on custom reports such as Molecular Custom are now limited to 50 characters e Session ID and Sample ID search in modules such as Manage Data and Reporter now suppo
5. at if this option is selected The translation is temporary and it will only translate results Please refer to item 5 above for more details b For combined and supplemental analysis the analysis results will be displayed in the new format even if one of the samples has been analyzed using old allele format 7 Reporting and viewing of results in HLA Fusion Research3 0 a The viewing and reporting of results will be based on what is in the database This means results in the old allele format will show old alleles and results in new allele format REVISION HISTORY Revision Date Revision Description HFR REL NOTE v3 x x EN 00 Rev 0 Page 5 of 5
6. ele name formats The catalog import process in HLA Fusion Research 3 0 software is as follows a Catalogs using the new allele naming format are imported as is Subsequent analysis reanalysis will use the new allele name and results will be stored in the new allele format Subsequent viewing and reporting modules will display alleles in the new format as well b Catalogs using the old allele format are supported as well In this case the software gives users the option to either import as is or translate and import in the new format If the translation option is selected HFR REL NOTE v3 x x EN 00 Rev 0 Page 4 of 5 One Lambda Inc Release Notes HLA Fusion Research 3 0 the old allele names are translated into new allele names during the import and any old alleles which do not have corresponding new alleles are dropped and not imported 5 Data Management a We have added a Translate option to the Data Management screen where selected sessions in the old allele format can be translated into the new allele format Changes made on this screen are updated in the database Please note that only results will be translated In addition please note the following b Other assignments Serology and NMDP code stay as is c Old alleles will be left as is if they do not have a matching new allele 6 Analysis a We have also added a Translation option to the analysis windows for Micro SSP to display old alleles in the new form
7. patient status e g CO in assessment C1 active listings C2 pending C3 transplanted and C9 deceased e The system now provides a Catalog Import Date column in the Catalog Management module e All Updates Available links for Product Catalogs now display the nomenclature date and revision notes e lf the user selects the Update Previously Downloaded Documents check box next to Get Docs from the auto update page in Update References the latest version of documents will be imported even if older versions were imported previously e The system now automatically detects if there is a software update patch and informs users of available updates The software update Upgrade feature is only available to HLA Fusion supervisor level users with Microsoft Windows admin rights e Users can now edit the Patient ID field in the Manage Sample Info to change an existing patient ID or add a patient e The system now supports transplant history for a given patient e The system now supports patient CDC CDC AHG and VX Cross matching in the patient management system e Users can now perform auto and manual as well auto import of P and G groups from the IMGT site e Users can now input Quantiplex CSV test files e Patient Session Sample information and Patient Tracking are now integrated as a Web application e Users can now save homozygous allele code assignments HFR REL NOTE v3 x x EN 00 Rev 0 Page 2 of 5 One Lambda Inc
8. rt Chinese characters e SSP Analysis now ignores the first well 1H when determining whether to analyze non amp wells with a positive and negative score e Wildcard searches are now available for the Sample ID filter in the Manage Data module The system now provides the option to group sessions by test date instead of session date in the navigator e The system now provides a configuration setting so that the user can choose not to see the warning message about requiring a certain screen resolution and is not forced to change the screen resolution e The system now enables switching users without the need to exit the application and then start again with a different login www onelambda com One Lambda Inc HFR REL NOTE v3 x x EN 00 Rev 0 21001 Kittridge Street Canoga Park CA 91303 USA Page 1 of 5 T 818 702 0042 F 818 702 6904 One Lambda Inc Release Notes HLA Fusion Research 3 0 e The system now provides a feature to prevent the overwriting of existing patient information in the Manage Patients module e The sample date is now displayed during analysis e Session ID patient ID well ID and test date are now included in the raw data reports from the analyses windows e The size of SSP gel image in the Custom SSP report is now larger than 700 pixels e Users can now rotate and zoom in out of gel images attached to the analysis e Users can now stay on the current sample after a Save or Confirm without moving to the ne
9. validation is successful the script now finishes otherwise the software displays an error message to reload the vials e The script now checks for leftover plates in the Luminex Centrifuge and Thermocycler e The script now requests the software to validate the reagent loading e The plate is now moved to shaker shaken for 30 seconds and moved back to slots e The 70 ul wash buffer is now dispensed to all the wells on the plate having sample e Users can now choose to select the exe path e Users can now choose to select the log path e Users can now select the report type for the plate design layout list both e Users can now choose the run with or without Luminex e Users can now select the Luminex software option between IS 2 3 and xPONENT 3 1 e Users can now select the incubator type used between Bio Rad DNA engine and Eppendorf Master Cycler e When there is an error in the run the software now sends email notification if the email notification is active The configurable accounts are Microsoft Outlook yahoo com AOL Hotmail and gmail com e When there is an error in the run the software now sends a text message to a phone number if the text notification is active The configurable text accounts shall be cdyne com eztexting com e The KIR session summary now displays user assigned values yes no instead of the software suggested values HFR REL NOTE v3 x x EN 00 Rev 0 Page 3 of 5 One Lambda Inc
10. xt sample e The system now provides separate fields for comments one for system status messages and one for user entered comments e When a global cutoff adjustment is made the system now records it in the comments for only those samples affected by the cutoff For example if a global cutoff adjustment is made and only 5 samples out of 96 samples are affected then the global cutoff status comment is recorded for those five samples only e The columns in the UMC Utrecht report labeled A1_1 Result and A1_2 Result now have 4 digit results excluding the Locus letter e g 03 01 e Users can now create a multi batch of patient lists by applying the individual patients lists from a Luminex patient list through the Plate Designer e Users can now import a batch of Micro SSP sessions including the ability to browse for files e Users can now search for a patient by sample ID local ID and other patient information e Users can now search for records by patient ID and then move archive or delete that patient s records as needed e Users can now generate the Catalog Information Report in the old format e The system now provides a field for the type of transplant the patient will or has received with a drop down list e g SPK simultaneous pancreas kidney transplantation KTA kidney transplant alone LDKT living donor kidney transplantation SPLK pancreas living donor kidney and Other There is another drop down field for
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