RA-25 Chemistry Analyzer User Manual
Contents
1. 14 16 18 20 22 24 26 28 30 32 34 36 38 40 42 44 46 48 50 4 5 Names of the Chemistry Tests Available for Programming Program Code Chemisiry ALB ALT AST CAL CHOL Cl CRTN DGOX GGTP HBDH HGB IgG LH Na PRL T4 THEO TRIG UREA OPI OP3 OPS OP7 OP9 General Instructions for Use 1 See the appropriate reagent kit insert for reconstitution of reagents preparation of daily working solutions and other details Use clean dry and seamless cuvettes for carrying out test procedure Use reliable quality micropipettes to dispense samples and reagents when performing the tests Follow test procedures for reading on the RA 25 Wipe the outer surface of the cuvette with tissue paper to remove finger marks before inserting into cuvette well for taking a reading Gently push the cuvette into the well by holding it from the top Insert until resistance is felt and a beep is sounded This beep signals the activation of reading If repeat reading is required press the ead key Do not lift cuvette from the cuvette well and insert again In case of power failure the RA 25 automatically switches over to battery mode The display will show a blinking B in the right corner In case of power failure during a fixed time or kinetic chemistry the analyzer will complete the test in process and report the result In battery mode only endpoint chemistries can be performed A2. 7 When the List key is pressed repeatedly all the tests which are already programmed and stored in the memory along with their respective code numbers will be displayed by the analyzer The list of chemistry tests can be printed through PGM CODE lt 98 gt Display Keypad PGM CODE lt gt 2 3 Display of Stored Programs Example 01 GLUC 10 URIC 19 Cl 02 UREA 11 ALKP 20 TBIL Sample Blank 03 CRTN 12 ALT 21 DBIL Sample Blank 04 BUN 13 AST 22 T3 05 CHOL 14 GGTP 23 T4 06 HDL 15 CPK 24 TSH 07 TRIG 16 CKMB 25 TBIL Bichromatic 08 ALB 17 LDH 09 TPR 18 CAL For Printing Display What You Do Insert PGM CODE lt gt Press e ENTER 1 Print Program 1 2 Printer ON off Press Yes PJ The printer starts printing stored programs 2 4 3 Analyzer Description Component Identification 3 2 Component Description and Functions 3 3 On Off Switch 3 3 Fuse Holder 3 3 Liquid Crystal Display Panel 3 3 Wavelength Selector 3 3 Incubator Block 3 3 Cuvette Well 3 3 Rechargeable Battery Backup 3 3 Socket 3 4 RS 232C Interface Connector 3 4 Printer 3 4 Keypad Description and Key Functions 3 4 3 1 Component Identification 3 2 Component Description and Functions On Off Switch The On Off switch is located at the rear of the analyzer In the the switch turns the electrical power on and in the p position the switch turns the electrical power off Fuse Holder The fuse holder is locat
3. Prompts on Display What You Do Response of RA 25 21 DBIL EPSB WL 546 FT 0 263 Sto NT At the end of the test programming press Stop The prompt Insert PGM CODE lt gt is displayed 6 14 Multipoint Chemistry Methods Generally hormone level determinations and drug level determinations are based on ELISA EIA methods and Immunoturbidimetric methods which involve plotting of multistandard curves since these are non linear methods The final result of an unknown sample is calculated from the standard curve The RA 25 has the following facilities for these specialized chemistries e location numbers 22 to 24 are reserved for the permanent storage of any multistandard chemistry e The readings of up to 6 standards can be stored in the memory e The calibration curve is stored in the memory and may be used for the subsequent test runs 6 15 Programming Multipoint Endpoint Chemistry Example T3 Prompts on Display Insert PGM CODE lt gt NAME test lt gt Insert MODE lt gt 1 2 KIN 3 Insert WL lt gt 340 405 505 546 UNITS lt gt 1 U L 2 U mL 3 MLT PT Y N CODE program lt gt IMP FOR STD VAL ENTRY SEE MANUAL STD 1 value lt gt STD 2 value lt gt What You Do Response of RA 25 Press 1 ENTER Yes No To see the next available wavelength on display press Press ENTER To see the next available units on display p
4. gt NAME test lt gt Insert MODE lt gt 1 2 KIN 3 FXT Insert WL lt gt 340 405 505 546 UNITS lt gt 1 U L 2 U mL 3 uU mL MLT PT Y N Standard Y N FACTOR value Linearity Limit Store Y N CODE program 6 10 What You Do Response of RA 25 J Press 1 ENTER 9998 To see the next available wavelength on display List M Press 1 1 ENTER To see the next available units on display press Press No Press 0 No Press 0 2 3 ENTER x c c c um Press 2 0 ENTER No Press 1 Yes Press ENTER Insert WL2 lt gt P 3 0 ENTER EV QOV To see the next available wavelength on display List 6 10 a Prompts on Display What You Do Response of RA 25 Program 25 The program is stored in memory STORING 25 TBIL EP WL 546 WL2 630 At the end of the test programming press Stop The prompt Insert PGM CODE lt gt is displayed 6 11 Endpoint with Sample Blank Mode Explanation There is a provision in RA 25 to run a test in endpoint with sample blank mode e Test location numbers 20 and 21 can be used for this purpose e Ifdesired these locations can also be used to store programs for fixed time and kinetic chemistries e The bilirubin test has been used to illustrate a detailed programming procedure 6 12 Programming Endpoint Chemistry with Factor and Sample Blank Example D Bilirubin Prompts on
5. 9 10 11 12 13 14 15 16 Endpoint factors are higher than routine and lower than expected absorbance values All kinetic fixed time results are lower or higher than expected HIGH SD is displayed in kinetic chemistry BELOW RANGE is displayed in multipoint chemistry OVER RANGE is displayed in multipoint chemistry RANGE ERROR is displayed ERROR is displayed in Indpoint Sample Blank mode 9999 is displayed Possible Cause s There is deterioration in lamp energy or filter The temperature circuit is faulty The reaction is nonlinear due to a high sample value b deterioration of reagent The test result is below the lowest calibrator concentration The test result is above the highest calibrator concentration In multipoint only one standard value 1s fed Absorbance of sample blank is more than the absorbance of sample Absorbance of solution is gt 2 5 8 3 Corrective Action Contact the nearest Bayer Service Representative Contact the nearest Bayer Service Representative a Dilute the sample appropriately and repeat the test b Replace the reagent Report the result as lower than the lowest calibrator value Dilute the sample and repeat the test or report the result greater than the upper limit of the last calibrator Reprogram with appropriate number of standards for multipoint Repeat the test Dilute the sample and repeat the test
6. At the end of the test programming press Stop The prompt Insert PGM CODE lt gt is displayed 6 6 Programming Kinetic Chemistry Example AST Prompts on Display What You Do Response of RA 25 Insert P PGM CODE lt gt oe ENTER NAME test P e List To see test menu on display press and Sto Insert MODE lt gt P 2 ENTER Insert WL lt gt P 3 To see the next available wavelength on display press UNITS lt gt 1 U L Press 1 To see the next available units on display press Insert DLY lt gt Press Insert DT lt gt Press 4 5 ENTER FACTOR value Press 1 7 4 ENTER t Linearity Limit P Store Y N Press 1 Yes 6 7 CODE program Press 1 3 Program 13 The program is stored in memory STORING 6 7 a Prompts on Display What You Do Response of RA 25 13 AST KIN WL 340 TEMP OK Sto NT At the end of the test programming press Stop The prompt Insert PGM CODE lt gt is displayed 6 8 Bichromatic Mode Explanation There is a provision in RA 25 to program store and run tests in bichromatic mode e location number 25 is reserved for the programming and permanent storage of a bichromatic test e Bilirubin which is run in bichromatic mode has been used to illustrate a detailed programming procedure 6 9 Programming Bichromatic Endpoint Chemistry with Factor Example T Bilirubin Prompts on Display Insert PGM CODE lt
7. It has a built in incubator block to incubate 12 cuvettes at a time The incubator block can maintain a constant temperature of 37 C for chemistries that require preincubation The test reading is taken directly by placing the cuvette into the cuvette well which is also thermally regulated at 37 C The test results are displayed and printed 2 Unpacking and Installation Unpacking Installation Battery Charging Instrument Setup and Operation 2 1 2 2 2 3 2 3 Unpacking The RA 25 Chemistry Analyzer and accessories are shipped in two separate cartons As each carton is opened and unpacked check the contents against the packing list The packing list is kept in the instrument carton The items of each carton are given below Instrument Carton Accessory Carton Code No 9091 Code No 9081 e RA 25 Micropipettes e User Manual e Micropipette Workstation e Autopak RA 25 e RA 25 Cuvettes 2x50 Cuvettes Working Instructions and e Test Tube Workstations 2 Nos Program Parameters File e Printer Paper Roll Pack of 4 e Dust Cover e Spare Lamp e Power Cord e Spare Fuse e Printer 2 2 Installation The RA 25 Chemistry Analyzer is a microprocessor controlled electronic instrument and be careful not to damage any component while unpacking and setting up the analyzer The RA 25 should be set up and operated by connecting it to a source of stable mains power supply 110 220 V ac through a proper socket It is re
8. Press 1 Yes CODE program Press fi Program 1 The program is stored in memory STORING 6 3 Store Y N Press 1 Yes 1 ENTER CODE program Press Tod Program 1 The program is stored in memory STORING 6 3 m Prompts on Display What You Do Response of RA 25 01 GLUC EP WL 505 STD 100 Sto NT At the end of the test programming press Stop The prompt Insert PGM CODE lt gt is displayed Programming Fixed Time Chemistry Example BUN Prompts on Display Insert PGM CODE lt gt NAME test lt gt Insert MODE lt gt 1 EP 2 KIN 3 FXT Insert WL lt gt 340 405 505 546 UNITS lt gt 1 U L 2 U mL 3 pU mL Insert DLY lt gt Range 2 120 sec Insert DT lt gt Range 25 900 sec Standard Y N STD value lt gt Linearity Limit lt gt 6 5 What You Do Response of RA 25 Press ENTER List To see test menu on display press and Sto Press ENTER Press 3 4 0 To see next available wavelength on display press Press 1 1 Yes Yes To see the next available units on display press Press 3 0 Gu No Press 1 ENTER No Press 1 4 0 Gu Programming Fixed Time Chemistry Example BUN Prompts on Display What You Do Response of RA 25 Insert P PGM CODE lt gt T oe ENTER NAME test Press 7 List To see test menu on display press and Sto Insert MODE lt gt 3 Insert WL lt
9. accidents alteration misuse neglect maintenance not performed by us or failure to operate the instrument in accordance with instructions Further we extend no warranty for malfunction or damage to our instruments due to use of reagents other than reagents manufactured or recommended by us 3 We reserve the right to make changes in design of this instrument without obligation to incorporate such changes into previously manufactured instruments Disclaimer of Warranties This warranty is expressly made in lieu of any and all other warranties express or implied including the warranties of merchantability and fitness for use Limitations of Liability In no event shall we be liable for indirect special or consequential damages even if we have been advised of the possibility of such damages For service under this warranty contact The Service Department Bayer Diagnostics India Ltd 589 Sayajipura Ajwa Road Baroda 390 019 Gujarat India Phone 91 265 562720 Fax 91 265 565103 Return this card to Bayer Diagnostics India Ltd within 10 ten days of installation of Bayer RA 25 Chemistry Analyzer Bayer RA 25 Warranty Registration Card Product Code No 9091 Date of Installation Date of Delivery Serial Number Installation Date Purchaser Address 10 5 Serial No PIN Certificate of Installation I certify that Bayer RA 25 has been satisfactorily installed Signatur
10. gt Press 3 4 To see the next available wavelength on display press 1 1 ENTER No No 1 4 4 0 Gu ves UNITS lt gt 1 U L 2 U mL 3 pU mL Insert DLY lt gt Range 2 120 sec Press 1 1 ENTER To see the next available units on display press Press No No 1 ENTER PCD No 1 4 0 ENTER UNITS lt gt 1 U L 2 U mL 3 pU mL Insert DLY lt gt Range 2 120 sec Press 1 1 ENTER To see the next available units on display press Press No No 1 ENTER PCD No 1 4 0 ENTER Insert DT lt gt Press 0 ED Range 25 900 sec No 1 GI No 1 4 0 ENTER Insert DT lt gt Press 0 ED Range 25 900 sec No 1 GI No 1 4 0 Gu 6 5 e d Y N Press 1 ENTER Standard Y N ve E No 4 4 0 ENTER d Y N Press 1 ENTER Standard Y N ve E No 4 4 0 ENTER STD value Press 2 0 ENTER Le 1 4 0 GI STD value Press 2 0 ENTER Le 1 4 0 GI 6 5 1 Linearity Limit Press 1 4 0 ENTER Store Y N Press 1 Yes CODE program P 4 ENTER 6 5 j Linearity Limit Press 1 4 0 GI 1 Yes t Store Y N Press Yes Store Y N Press Yes CODE program 4 ENTER 6 5 n 6 5 0 Prompts on Display What You Do Response of RA 25 Program 4 The program is stored in memory STORING 04 BUN FXT WL 340 TEMP OK
11. 9 Service Information When You Have a Problem with the System How to Report the Problem First Second Third Replacement Parts and Accessories Where to Order 9 1 9 3 9 3 9 3 9 3 9 4 9 4 When You Have a Problem with the System e Section 8 Troubleshooting in this manual If Section 8 cannot assist you in solving the problem answer all questions listed on the facing page before contacting us for help The requested information will help identify the cause of the particular problem 9 2 How to Report the Problem First Record the following information Instrument Serial Number Installation Date Second Complete the following Questionnaire 1 Has Section 7 Instrument Care Maintenance and Minor Repair been reviewed Yes 2 Turn the instrument on Yes Is CHE C K displayed 3 If Step 2 answer is No is the instrument plugged into a live ac electrical outlet or was the Yes battery discharged before E 4 Does the instrument warm up Yes 5 Do characters or numbers on display appear partially displayed Yes 6 Does the printer provide a complete printout Yes LI 7 List error flag messages that have occurred 8 Record the exact sequence of events that took place when the failure occurred and results you have obtained Third Contact Bayer Instrument Service Engineer Application Specialist as appropriate 9 3 Replacement Parts and
12. Display Insert PGM CODE lt gt NAME test lt gt Insert MODE lt gt 1 2 KIN 3 FXT Insert WL lt gt 340 405 505 546 UNITS lt gt 1 U L 2 U mL 3 pU mL MLT PT Y N Standard Y N FACTOR value Linearity Limit Store Y N CODE program PGM FOR SAMPLE 6 13 What You Do Response of RA 25 Press 1 5 ENTER Press 1 GI 000 To see the next available wavelength on display List Press 1 1 ENTER To see the next available units on display press Press 0 No Press 0 No Press 0 2 Press 2 0 ENTER No Press 1 Yes Press ENTER Yes Programming Endpoint Chemistry with Factor and Sample Blank Example D Bilirubin Prompts on Display What You Do Response of RA 25 Insert P NAME test Press f 1 5 ENTER 1 GI 1 1 ENTER 0 No 0 No 0 2 3 ENTER MOOD 2 0 ENTER 1 Yes 2 1 ENTER c J P 6 13 a Insert MODE lt gt 1 EP 2 KIN 3 FXT Press 1 Eu 9990 1 1 ENTER 6 13 b 0 No 0 No No No 1 Yes d Yes Insert MODE lt gt 1 EP 2 KIN 3 FXT Press 1 ENTER 9990 1 1 ENTER SAC 6 13 c 0 No 0 No No No 1 Yes d Yes 0 405 50s 5 ne n 340 405 505 546 To see the next available wavelength on display 1 1 ENTER 0 No 0 No cx c No 1 Yes 9 Yes 6 13 d 0 405
13. Explanation 6 12 Programming Endpoint Chemistry with Factor and Sample Blank Example D Bilirubin 6 13 Multipoint Chemistry Methods 6 15 Programming Multipoint Endpoint Chemistry Example T3 6 16 6 1 Programming the Test Parameters The open programs can be programmed for any chemistry tests which are not available in the test directory All the test parameters of the existing programs can be accessed through PGM CODE lt 99 gt to suit the requirement The following are the options available for each parameter Parameters Available Options Mode 1 EP 2 KIN 3 FXT Units 1 U L 2 U mL 3 4 mEq L 5 M L 6 7 8 9 mmo L ng mL 96 10 g L 11 mg dL 12 fi dL 13 g dL 14 fif mL 15 mg L Factor EP amp FXT 0 001 9 999 Factor Kinetic 0001 9999 Standard Concentration 1 999 0 999 for Multipoint Interval Time DT 25 900 sec Delay Time DL Y 2 120 sec Wavelength 340 405 505 546 630 nm 6 2 Programming Endpoint Chemistry Example Glucose Prompts on Display What You Do Response of RA 25 Insert P NAME test Press 1 Gu e List To see test menu on display press Stop then press Insert MODE lt gt 1 1 2 KIN 3 FXT eng Insert WL lt gt P 5 5 FELIS yem To see the next available wavelength on display press UNITS lt gt 1 U L Press 1 1 2 U mL 3 VA yes To see the next available units on display p
14. RA 25 takes reading ABS 0 200 The test result along with the absorbance is 7 3 ng mL displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt Insert PGM CODE is displayed 5 9 Multipoint Chemistry Using Standard Curve from Memory Example T3 Prompts on Display Insert PGM CODE lt gt 22 EP WL 405 MLT PT 22 T3 EP Calib Y N 22 EP Insert BLANK 22 EP Blanking 22 EP Insert SAMPLE What You Do Response of RA 25 Press ENTER Select 405 filter and press 0 Press No parameters The printer prints the test Insert cuvette containing reagent into the cuvette well RA 25 sets to zero Insert cuvette containing reacted solution of sample into the cuvette well RA 25 takes reading ABS 0 200 The test result along with the absorbance is 7 3 ng mL displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt Insert PGM CODE is displayed 6 Programming the Tests Programming the Test Parameters 6 2 Programming Endpoint Chemistry Example Glucose 6 3 Programming Fixed Time Chemistry Example BUN 6 5 Programming Kinetic Chemistry Example AST 6 7 Bichromatic Mode Explanation 6 9 Programming Bichromatic Endpoint Chemistry with Factor Example T Bilirubin 6 10 Endpoint with Sample Blank Mode
15. disconnected from all power sources e When the instrument is open and in the power on mode do not perform maintenance procedures change parts or make repairs or adjustments In a circumstance where this work must be done it must only be carried out by a trained expert familiar with the dangers e Only use fuses of the type specified and with the current rated Do not use repaired fuses Do not short circuit the fuse holder e Ifsafe operation of the instrument can no longer be ensured switch off the power Make sure the instrument cannot be switched on by mistake e Safe operation is no longer guaranteed when the instrument o 15 visibly damaged o isnot working o been improperly stored for some time o has been transported under unfavourable conditions e All products or objects that come into contact with human blood even after cleaning should be handled as if capable of transmitting viral diseases Wear protective eyeware gloves and clothing The user should follow the guidelines for prevention of blood borne transmissible disease in health care settings as recommended in Protection of Laboratory Workers from Infectious Disease Transmitted by Blood Body Fluids and Tissues 2nd edition Approved Guideline 1977 Document M29A promulgated by the National Committee for Clinical Laboratory Standards NCCLS This document has complete information about user protection against potentially infectious human blood specimens an
16. the relative humidity at 30 is 85 Maintenance External cleaning of the instrument should be carried out daily at the end of the day or as and when required The following procedure is to be followed for cleaning the instrument 1 Switch off the instrument 2 Clean the exterior of the instrument with a lint free cloth dampened with water Be careful so as to prevent water from dripping into the cuvette well wavelength selector incubator block area 3 Dry the instrument with a lint free cloth Cleaning the Cuvette Well Whenever dust particles are observed inside the cuvette well carryout the following procedure for cleaning 1 Switch off the instrument 2 Blow air or use mild vacuum to clean 7 3 Minor Repair You can replace the fuse and the printer paper Replacing Fuse 1 2 3 4 5 Switch off the instrument Remove the fuse holder by rotating it counterclockwise Remove the old fuse from the fuse holder and insert a new 1 A fuse Code No 9084 Replace the fuse holder by rotating it clockwise Switch on the instrument and confirm that it is working Replacing Printer Paper Paper Type Thermal 56 mm width Code No 9071 1 2 Switch off the instrument and the printer Remove the printer cover by applying light inward pressure to its back panel and then pull it upward to detach and remove Remove spindle from paper roll holder and discard the empty paper roll core NOTE
17. to clear the last entry This key is effective only if pressed before the Jnter key is Clear pressed ENTER Press to register the selected command in the computer 1 lt lt 3 4 Press to take the reading of a sample again with the cuvette already in the cuvette well Press to abort the current operation List Press to see list of tests on the LCD If the J ist key is pressed when Insert PGM CODE lt gt prompt is on the display the names and code numbers of all preprogrammed tests are displayed e Ifthe 4ist key is pressed while programming a test when NAME test lt gt prompt is on the display the test directory of all the 50 tests is displayed If the tist key is pressed while programming a test when Insert WL gt or UNITS lt gt prompt is on the display the lists of available wavelengths and units for the appropriate selection are displayed e Repeated pressing of the JEist key results in the scrolling of information on the display Keypad SLE LZ Yes Cigar 3 5 4 Operating Principles Test Directory and General Instructions for Use Operating Principles 4 2 Calculation of Results 4 3 Endpoint Chemistry 4 3 Fixed Time Chemistry 4 3 Kinetic Chemistry 4 3 Test Directory 4 5 General Instructions for Use 4 6 4 1 Operating Principles The light beam from the tungsten filament lamp with lens passes through a slit The beam then passes throu
18. 1 2 ENTER Press ENTER Press The printer prints the test parameters Insert cuvette containing distilled water into the cuvette well RA 25 sets to zero Insert cuvette containing sample blank into the cuvette well RA 25 takes reading Insert cuvette containing reacted solution of sample into the cuvette well RA 25 takes reading The result is displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press Stop The prompt Insert PGM CODE lt gt is displayed 5 8 Multipoint Chemistry with Calibrators Example T3 Prompts on Display PGM CODE lt gt 22 EP WL 405 MLT PT 22 T3 EP Insert BLANK 22 T3 EP Blanking 22 EP Insert STD1 22 T3 EP Calibration 22 T3 EP ABS1 1 084 What You Do Response of RA 25 Press ENTER Select 405 filter and press Insert cuvette containing reagent into the cuvette well RA 25 sets to zero Insert cuvette containing reacted solution of STD 1 into the cuvette well RA 25 performs calibration ENTER Press Likewise the RA 25 will provide instructions to read standards as per programmed parameters and to store the absorbances in the memory On completion of calibration the printer prints the test parameter along with absorbances of all standards 22 EP Insert SAMPLE Insert cuvette containing reacted solution of sample into the cuvette well
19. 50s 5 ne n 340 405 505 546 To see the next available wavelength on display 1 1 ENTER SAC 0 No 0 No cx c No 1 Yes 9 Yes 6 13 e 0 No 0 No Ji No 7 Yes 2 1 ENTER eG 6 13 f 0 No 0 No Ji No 7 Yes 2 1 ENTER eG 6 13 g UNITS lt gt 1 U L Press 1 1 To see the next available units on display press 0 No 0 No 0 2 3 ENTER JAQ 2 0 ENTER No 1 Yes 2 1 ENTER JEJE 6 13 h UNITS lt gt 1 U L Press 1 1 To see the next available units on display press 0 No 0 No 0 2 3 ENTER JAQ 2 0 ENTER No 1 Yes 2 1 ENTER JEJE 6 13 i 0 No 0 No JJO No 2 0 ENTER No 1 Yes Yes 6 13 j 0 No 0 No JJO No 2 0 ENTER No 1 Yes Yes 6 13 k MLT PT Y N Standard Y N FACTOR value 6 13 1 Press No Press 0 No No Bi No 1 Yes Yes MLT PT Y N Standard Y N FACTOR value Press No Press 0 No No Bi No 1 Yes Yes 6 13 m Linearity Limit Press 2 0 ENTER lt gt No 1 Yes Yes 6 13 n Linearity Limit Press 2 0 ENTER lt gt No 1 Yes Yes 6 13 0 Store Y N Press Ms Yes 6 13 p 7 Store Y N Press M Yes 6 13 q CODE program Press 2 1 ENTER Cu PGM FOR SAMPLE BLANK METHOD Program 21 The program is stored in memory STORING V 6 13 r 6 13 s
20. Accessories Product Code No Description 9082 Bayer RA 25 Cuvettes 50 cuvettes box 9083 RA 25 Dust Cover 9084 RA 25 Fuse 1 A 9085 RA 25 Lamp Assembly 9071 RA 25 Printer Paper Roll pack of 4 RA 25 User Manual Document Number TAO 0405 00 Where to Order For pricing and information on ordering replacement parts and accessories contact your nearest RA 25 Representative 9 4 10 Technical Specifications Safety Notes Warranty Technical Specifications 10 2 Safety Notes 10 3 Warranty 10 4 Manufacturer s Warranty 10 4 Disclaimer of Warranties 10 4 Limitations of Liability 10 4 Warranty Service 10 4 10 1 Technical Specifications Power Requirement Fuse Requirement Power Consumption Operating Modes Wavelength Range Band Pass Light Source Photometric Range Photometric Accuracy Drift Zero Setting Operating Conditions Kinetic Program Display Type Printer Type Microprocessor Memory Interface Cuvette Well Incubator Block Battery Backup Cuvettes Dimensions Weight 220 V ac 50 Hz or 110 V ac 60 Hz 1A Max 50 Watts Absorbance Endpoint Fixed Time and Kinetic Interference filters mounted in a 5 position filter wheel 340 405 505 546 and 630 nm 710 nm Tungsten 3 7 V 1 W 2 500 A to 2 500 A 23 lt 0 005 A per hour Automatic 189 to 329 Max 85 noncondensing at 30 Delay Time 2 120 sec Interval Time 25 900 sec No of deltas 4 fixed Alphan
21. Cause s The reported test result exceeds linearity limit a There is no ac mains power supply b RA 25 on Battery mode The fuse is blown The lamp is fused a The lamp is not illuminating b There is no change in the reagent absorbance after reaction with std The printer is not switched on The paper installation is incorrect c The printer cable is loose d The printer is switched off through d PGM CODE lt 98 s The temperature circuit is faulty a The voltage is low b There is no ac mains supply or battery backup 8 2 Corrective Action Dilute the sample and repeat the test Check mains power supply Replace the fuse If problem persists contact the nearest Bayer Service Representative Press and observe for lamp illumination in the cuvette well If no glow is seen contact the nearest Bayer Service Representative a Contact the nearest Bayer Service Representative b Develop a new standard tube and recalibrate a Switch on the printer b Install the paper correctly and check paperfeed action c Check and refit the printer cable connectivity Switch on the printer through PGM CODE lt 98 gt Contact the nearest Bayer Service Representative Check the ac voltage and keep the instrument on for battery recharging Replace the fuse If problem persists contact the nearest Bayer Service Representative Flagging Problem
22. FT 3 000 04 BUN FXT Insert SAMPLE 04 BUN FXT DLY 30 DT60 04 BUN 1 410 mg dL 15 What You Do Response of RA 25 ENTER Press ENTER Select 340 filter and press Insert cuvette containing distilled water into the cuvette well RA 25 sets to zero Insert cuvette containing solution of standard into the cuvette well The countdown of the delay time is displayed and started and then the first absorbance reading is taken The second absorbance reading is taken at the end of the Delta Time DT The factor is then calculated and stored in the memory ENTER Press The printer prints the test parameters along with factor Insert cuvette containing solution of sample into the cuvette well The countdown for the delay and Delta Times is displayed The result is displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt Insert PGM CODE is displayed 5 4 Precalibrated Fixed Time Chemistry Using Old Factor Example BUN Prompts on Display Insert PGM CODE lt gt 04 BUN FXT WL 340 TEMP OK 04 BUN FXT Calib Y N 04 BUN FXT Insert BLANK 04 BUN FXT Blanking 04 BUN FXT Insert SAMPLE 04 BUN FXT DLY 30 DT 60 04 BUN 1 410 mg dL 15 What You Do Response of RA 25 ENTER Press ENTER Select 340 filter and press 0 No Press The printer prints the test parameter Insert cuvette c
23. If paper remains on roll and in printer tear the paper at a point before it enters the printer Then pull remaining piece of paper forward through the printer Pulling the paper backward may damage the printer Using scissors cut the corners off the leading edge of the new roll of paper Insert the spindle into the roll of paper then insert spindle and new paper roll into the paper roll holder IMPORTANT Paper should feed from bottom of roll Insert the leading edge of the paper into the slot meant for the insertion NOTE To avoid uneven paper feeding make sure the paper is tightly wound 7 4 7 Switch on the instrument and printer Press Paper Feed key to advance the paper 8 Insert the paper through the slot in the printer cover 9 Replace the printer cover 7 4 a 8 Troubleshooting Flag Messages and Troubleshooting Guide 8 1 Flag Messages and Troubleshooting Guide Flagging Problem 1 An asterisk appears after the test result Blinking B appears on upper right corner of the display Blinking B appears on upper right corner of display even when ac mains power 1s available Result for endpoint chemistry is 9999 Result for FXT is 9 999 The factor displayed for endpoint or fixed time chemistry is 9 999 The printer does not print TEMP remains blinking for a long time for example gt 25 min at 220 V or for gt 35 min at 110 V The display is blank when switched on Possible
24. RA 25 Chemistry Analyzer User Manual Bayer amp Trademarks and Copyright RA is a registered trademark of Bayer Corporation 92000 Bayer Diagnostics India Ltd All rights reserved Bayer Diagnostics India Ltd 589 Sayajipura Ajwa Road Baroda 390 019 Gujarat India No part of this manual or the products it describes may be reproduced by any means or in any form without prior consent in writing from Bayer Diagnostics India Ltd Bayer Diagnostics India Ltd retains the right to make changes to the instrument and this document Your local Bayer Service Representative will provide the latest revision of this document Document Number TA0 0405 00 Contents 1 Introduction General Description 2 Unpacking and Installation Unpacking Installation Battery Charging Instrument Setup and Operation 3 Analyzer Description Component Identification Component Description and Functions On Off Switch Fuse Holder Liquid Crystal Display Panel Wavelength Selector Incubator Block Cuvette Well Rechargeable Battery Backup Socket RS 232C Interface Connector Printer Keypad Description and Key Functions 4 Operating Principles Test Directory and General Instructions for Use Operating Principles Calculation of Results Endpoint Chemistry Fixed Time Chemistry Kinetic Chemistry Test Directory General Instructions for Use 5 Analyzing Samples Endpoint Chemistry Using Standard Example Glucose Precalibrated Endpoint Chemistry Usin
25. ches over to battery mode and this is indicated on the upper right corner of the LCD by a flashing B The battery is continuously charging when the RA 25 is operating on the ac mains supply 3 3 Only endpoint chemistries can be performed on the battery mode The following kinetic and fixed time chemistries which are temperature dependent cannot be performed when the RA 25 is operating in the battery mode ACPH ALKP ALT AMYL AST BUN CHE CKMB CPK CRTN GGTP HBDH LDH Socket A socket is provided on the back panel for connecting the RA 25 to the mains with the power cord RS 232C Interface Connector RS 232C interface is provided on the back panel for connecting the RA 25 printer Printer This is a 24 column thermal printer which uses a thermal paper of 56 mm width The On Off switch is located on the right side panel of the printer The printer prints test code test name type of reaction parameters sample ID and test results The Feed key is provided on top of the printer Keypad Description and Key Functions There are 16 keys on the keypad The following are their functions 1 Press Yes e to enter digit or to answer es to a prompt displayed on the LCD or e display 4 deltas after the result of a kinetic chemistry is displayed 0 Press to enter digit or to answer 0 to a prompt displayed on the LCD No Press to enter the respective digits E Press to enter the decimal point Press
26. commended that the RA 25 be used in a closed dust free and air conditioned environment Battery Charging At the time of shipment the rechargeable battery pack in the RA 25 Chemistry Analyzer is in a fully discharged condition Therefore it will need a start up procedure for charging which is as follows Switch on the mains supply and CVT Constant Voltage Transformer but do not switch on the RA 25 Chemistry Analyzer This keeps the supply amp n to the battery charging circuit Approximately 90 hours will be required to fully charge the battery This can be achieved by keeping the mains and CVT on as mentioned above continuously for 6 days Please note that the battery gets recharged automatically as and when the RA 25 Chemistry Analyzer is in use Instrument Setup and Operation 1 Place the RA 25 on a firm surface in the designated work area A CAUTION The correct voltage must be set to avoid damage to the instrument 2 Ensure appropriate voltage selection 110 V 220 V by setting the switch on the back panel to the desired voltage 3 Plug the power cord to the mains 4 Ensure paper roll is loaded in the printer Attach the printer cable to RS 232C port on the back panel of the instrument 5 Switch on the RA 25 CHECK prompt is displayed momentarily on the LCD and then Insert CODE lt gt message is displayed on the LCD 6 Allow the analyzer to warm up for at least 20 minutes ambient temperature 25 to attain 37
27. d can be used as background material for instruction 10 3 Warranty Manufacturer s Warranty Bayer Diagnostics India Ltd warrants to the original purchaser that the RA 25 Chemistry Analyzer for a period of one 1 year will be free from defects in materials and workmanship from the date of original purchase and or installation except as noted below During the stated warranty period above we shall replace with a reconditioned unit or at its option repair at no charge a unit that is found to be defective This warranty is subject to the following exceptions and limitations 1 90 day warranty only will be extended for consumable parts and or accessories 2 This warranty is limited to repair or replacement due to defects in parts or workmanship Parts required which were not defective shall be replaced at additional cost and we shall not be required to make any repairs or replace any parts which are necessitated by abuse accidents alteration misuse neglect maintenance not performed by us or failure to operate the instrument in accordance with instructions Further we extend no warranty for malfunction or damage to our instruments due to use of reagents other than reagents manufactured or recommended by us 3 reserve the right to make changes in design of this instrument without obligation to incorporate such changes into previously manufactured instruments Disclaimer of Warranties This warranty is expressly made
28. e of Purchaser or Authorized Representative Name of Purchaser IN BLOCK LETTERS Tear Out amp Mail Return this card to Bayer Diagnostics India Ltd within 10 ten days of installation 10 5 a
29. ed at the rear of the analyzer It holds a 1A fuse Liquid Crystal Display Panel The RA 25 has a 16 x 2 character alphanumeric display It displays test name test result test absorbance delay and reading times kinetic mode and operational messages Wavelength Selector The wavelength selector allows the operator to select wavelength from 340 630 nm through 5 interference filters 340 405 505 546 630 nm The desired wavelength can be selected by rotating the wavelength selector Incubator Block The incubator block is preset to maintain 37 when the analyzer is connected to the mains and can hold 12 round cuvettes The basic function of this incubator block is to provide the necessary incubation temperature to reagents or reacted solutions where required The heater circuit in the incubator block is automatically shut off when operation switches over to battery mode Cuvette Well The cuvette well is controlled at 37 temperature when the analyzer is connected to the mains It holds a round cuvette for taking readings At the bottom of the cuvette well a sensing switch is provided This gets activated when a cuvette is fully inserted in the cuvette well A reading is taken and the result is displayed The heater circuit in the cuvette well is automatically shut off when operation switches over to battery mode Rechargeable Battery Backup This battery pack has a 9 6 V Ni Cd battery When the mains supply fails the RA 25 automatically swit
30. ess The printer prints test parameters with factor Insert cuvette containing reacted solution of sample into the cuvette well RA 25 takes reading The result is displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt Insert PGM CODE gt is displayed 5 2 Precalibrated Endpoint Chemistry Using Old Factor Example Glucose Prompts on Display PGM CODE lt gt 01 GLUC EP WL 505 STD 100 01 GLUC EP Calib Y N 01 GLUC EP Insert BLANK 01 GLUC EP Blanking 01 GLUC EP Insert SAMPLE 01 GLUC EP Sampling 01 GLUC EP mg dL 95 What You Do Response of RA 25 1 ENTER Press ENTER Select 505 filter and press 0 Press No parameters The printer prints the test Insert cuvette containing reagent into the cuvette well RA 25 sets to zero Insert cuvette containing reacted solution of sample into the cuvette well RA 25 takes reading The result is displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press Stop The prompt Insert PGM CODE lt gt is displayed 5 3 Fixed Time Chemistry Using Standard Example BUN Prompts on Display Insert PGM CODE lt gt 04 BUN FXT WL 340 TEMP OK 04 BUN FXT Insert BLANK 04 BUN FXT Blanking 04 BUN FXT Insert STD 04 BUN FXT DLY 30 DT 60 04 BUN FXT
31. g Old Factor Example Glucose Fixed Time Chemistry Using Standard Example BUN 111 1 1 1 2 2 1 2 2 2 3 2 3 2 3 3 1 3 2 3 3 3 3 3 3 3 3 3 3 3 3 3 4 3 4 3 4 4 1 4 2 4 3 4 3 4 3 4 3 4 5 4 6 5 1 5 2 5 3 5 4 Contents Cont Precalibrated Fixed Time Chemistry Using Old Factor Example BUN Kinetic Chemistry Example ALT Bichromatic Endpoint Chemistry Using Factor Example T Bilirubin Endpoint Chemistry Using Factor and Sample Blank Example D Bilirubin Multipoint Chemistry with Calibrators Example T3 Multipoint Chemistry Using Standard Curve from Memory Example T3 6 Programming the Tests Programming the Test Parameters Programming Endpoint Chemistry Example Glucose Programming Fixed Time Chemistry Example BUN Programming Kinetic Chemistry Example AST Bichromatic Mode Explanation Programming Bichromatic Endpoint Chemistry with Factor Example T Bilirubin Endpoint with Sample Blank Mode Explanation Programming Endpoint Chemistry with Factor and Sample Blank Example D Bilirubin Multipoint Chemistry Methods Programming Multipoint Endpoint Chemistry Example T3 7 Instrument Care Maintenance and Minor Repair Instrument Care Maintenance Cleaning the Cuvette Well Minor Repair Replacing Fuse Replacing Printer Paper 8 Troubleshooting Flag Messages and Troubleshooting Guide 9 Service Information When You Have a Problem with the System How to Report
32. gh the reacted solution in the cuvette and goes through the selected interference filter The beam of selected wavelength falls on the solid state photodetector which generates an electrical signal which is proportional to the intensity of the incident light 4 2 Calculation of Results Endpoint Chemistry The reacted solution in the cuvette absorbs light depending upon the concentration of the constituent being determined Therefore the signal generated by the photodetector is in inverse logarithmic proportion to the concentration of the constituent in the solution The final result is calculated using the factor derived from a known standard The RA 25 calculates the factor using the following formula Concentration of Standard Absorbance of Standard Factor The RA 25 multiplies the sample absorbance with the factor to provide the final result If the factor is known it may also be entered directly Fixed Time Chemistry In this type of chemistry the RA 25 takes two absorbance readings of the sample at a fixed time interval 1 which is taken immediately at the end of the difelay time 2 H52 which is taken immediately at the end of the interval time The RA 25 calculates the A abs T1 T2 absorbance difference for the sample and multiplies it by the factor to get the result The factor is computed by running a standard prior to running the sample or may be entered directly by the operator Conce
33. in lieu of any and all other warranties express or implied including the warranties of merchantability and fitness for use Limitations of Liability In no event shall we be liable for indirect special or consequential damages even if we have been advised of the possibility of such damages Warranty Service For service under this warranty contact The Service Department Bayer Diagnostics India Ltd 589 Sayajipura Ajwa Road Baroda 390 019 Gujarat India Phone 91 265 562720 Fax 91 265 565103 Serial Number Installation Date 10 4 RA 25 RA 25 Chemistry Analyzer CPE MER Warranty Bayer Diagnostics India Ltd warrants to the original purchaser that the RA 25 Chemistry Analyzer for a period of one 1 year will be free from defects in materials and workmanship from the date of original purchase and or installation except as noted below During the stated warranty period above we shall replace with a reconditioned unit or at its option repair at no charge a unit that is found to be defective This warranty is subject to the following exceptions and limitations 1 90 day warranty only will be extended for consumable parts and or accessories 2 This warranty is limited to repair or replacement due to defects in parts or workmanship Parts required which were not defective shall be replaced at additional cost and we shall not be required to make any repairs or replace any parts which are necessitated by abuse
34. nsert PGM CODE is displayed 5 6 Bichromatic Endpoint Chemistry Using Factor Example T Bilirubin Prompts on Display Insert PGM CODE lt gt 25 TBIL EP WL 546 WL2 630 SETWL 546 Insert BLANK SETWL 546 Blanking SET WL2 630 Insert BLANK SET WL2 630 Blanking SET WL2 630 Insert SAMPLE SET WL2 630 Sampling SET WL 546 Insert SAMPLE SET WL 546 Sampling SET WL 546 mg dL1 2 What You Do Response of RA 25 Press ENTER Press The printer prints the test parameters Select 546 filter and insert cuvette containing distilled water into the cuvette well RA 25 sets to zero at 546 nm wavelength Read Select 630 filter and press RA 25 sets to zero at 630 nm wavelength Insert cuvette containing reacted solution of sample into the cuvette well RA 25 takes reading Read Select 546 filter and press RA 25 takes reading The result is displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt Insert PGM CODE is displayed 5 7 Endpoint Chemistry Using Factor and Sample Blank Example D Bilirubin Prompts on Display Insert PGM CODE lt gt 21 DBIL EPSB WL 546 FT 0 263 21 DBIL EPSB Insert BLANK 21 DBIL EPSB Blanking 21 DBIL EPSB Insert SMPL BLK Blanking Insert SAMPLE Mg dL 0 2 Insert SMPL BLK What You Do Response of RA 25
35. ntration of Standared T1 T2 A Absorbance of Std Factor The sample result is obtained from the following equation Test result A Abs of Test x Factor Kinetic Chemistry When a kinetic chemistry is being run the RA 25 measures the change in absorbance of the test solution in the cuvette at a fixed interval of time according to programmed parameters The result is calculated by multiplying the rate of change of absorbance per minute by the preprogrammed factor The enzyme activity is reported in U L Enzyme activity U L Average A Absorbance minute x Factor The factor is provided in the reagent kit insert and is derived as follows TV x10 Factor SV x ECx LP 4 3 Where TV is the total volume in mL of reagent and sample in the reaction SV is the sample volume in mL EC is the molar extinction coefficient for the reaction compound at the wavelength being measured LP is the light path in centimeters 106 is the conversion factor incorporating conversion of millimoles of substrate to micromoles and millilitres of serum to litres 4 4 Test Directory Program Code Chemistry 01 03 05 07 09 11 13 15 17 19 21 23 25 27 29 31 33 35 37 39 41 43 45 47 49 ACPH ALKP AMYL BUN CHE CKMB CPK DBIL FSH GLUC HDL IgA IgM LDH MAG PHOS T3 TBIL TPR TSH URIC OP2 OP4 OP6 OP8 02 04 06 08 10 12
36. ontaining distilled water into the cuvette well RA 25 sets to zero Insert cuvette containing solution of sample into the cuvette well The countdowns for the delay and Delta Times are displayed The result is displayed and printed Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt Insert PGM CODE is displayed 5 5 Kinetic Chemistry Example ALT Prompts on Display Insert PGM CODE lt gt 12 ALT KIN WL 340 TEMP OK 12 ALT KIN Insert BLANK 12 ALT KIN Blanking 12 ALT KIN Insert SAMPLE 12 ALT KIN DLY 60 DT 45 U L100 1 100 What You Do Response of RA 25 1 2 EL ENTER P Tess ENTER Select 340 filter and press The printer prints the test parameters Insert cuvette containing distilled water into the cuvette well RA 25 sets to zero Insert cuvette containing reacted solution of sample into the cuvette well The countdown of the delay time is displayed and started and the initial absorbance is recorded Then the countdown of the Delta Times interval is started for all 4 readings At the end the final result is displayed along with the initial absorbance The printer prints the final result initial absorbance and 4 deltas Note Press 4 to display all the 4 delta readings on LCD Sto Subsequent samples can be read as mentioned above At the end of the test run press So The prompt I
37. ress MLT PT Y N 2 Press O No Standard Y N Press 1 Yes STD value Press 1 0 0 Linearity Limit 5 No No Store Y N 2 Press 1 Yes r 6 3 Programming Endpoint Chemistry Example Glucose Prompts on Display What You Do Response of RA 25 Insert P NAME test Press 1 Gu e List To see test menu on display press and then press Insert MODE lt gt P 1 1 EP 2 KIN 3 FXT Insert WL lt gt P 5 5 FELIS Cyy yem To see the next available wavelength on display 1 1 0 No 1 Yes 0 0 ENTER Secs No No 1 Yes press UNITS lt gt 1 U L Press 1 1 To see the next available units on display press MLT PT Y N Press 0 No 1 Yes 1 0 0 ENTER 5 w Cio vo 1 Yes press UNITS lt gt 1 U L Press 1 1 To see the next available units on display press MLT PT Y N Press 0 No 1 Yes 1 0 0 ENTER 5 w Cio vo 1 Yes Standard Y N Press 1 Yes 1 0 0 ENTER No No 1 Yes Standard Y N Press 1 Yes 1 0 0 ENTER B No No 1 Yes 6 3 e STD value Press 1 0 0 ENTER JJ III Cue S J E888 1 Yes STD value Press 1 0 0 ENTER JJ III Cue S J E888 1 Yes 6 3 g Linearity Limit Press 5 0 0 lt gt No No 1 Yes Linearity Limit Press 5 0 0 lt gt No No 1 Yes 6 3 1 Store Y N
38. ress Press 1 Yes Press ENTER ENTER Press to insert 0 3 digits after decimal point uniformly for all standard values Press keys representing the value of standard 1 with appropriate decimal position and then ENTER press Press keys representing the value of standard 2 with the decimal position same as for standard 1 and then press ENTER Similarly enter the concentrations of all the remaining standards with same number of decimal positions as in standards 1 and 2 and press If the test requires less then 6 standards then at the end of the last standard entry press 6 16 a Prompts on Display What You Do Response of RA 25 Program 22 The program is stored in memory STORING 22 EP WL 405 MLT PT At the end of the test programming press Stop The prompt Insert PGM CODE lt gt is displayed 6 17 7 Instrument Care Maintenance and Minor Repair Instrument Care 7 2 Maintenance 7 3 Cleaning the Cuvette Well 7 3 Minor Repair 7 4 Replacing Fuse 7 4 Replacing Printer Paper 7 4 7 1 Instrument Care The RA 25 instrument contains sensitive electronics and optics e Handle the instrument with extreme care e Do not operate the instrument in direct sunlight e Do not operate the instrument in extreme high temperatures and high humidity Do not operate instrument where the power supply is unstable e Ensure that the operating environment is dust free the temperature is between 18 and 32 and
39. t the end of the day switch off the RA 25 clean the outer surface of the instrument and cover with dust cover It is recommended to calibrate the instrument with a standard in each batch of endpoint and fixed time tests 4 6 5 Analyzing Samples Endpoint Chemistry Using Standard Example Glucose 5 2 Precalibrated Endpoint Chemistry Using Old Factor Example Glucose 5 3 Fixed Time Chemistry Using Standard Example BUN 5 4 Precalibrated Fixed Time Chemistry Using Old Factor Example BUN 5 5 Kinetic Chemistry Example ALT 5 6 Bichromatic End point Chemistry Using Factor Example T Bilirubin 5 7 Endpoint Chemistry Using Factor and Sample Blank Example D Bilirubin 5 8 Multipoint Chemistry with Calibrators Example T3 5 9 Multipoint Chemistry Using Standard Curve from Memory Example T3 5 10 5 1 Endpoint Chemistry Using Standard Example Glucose Prompts on Display PGM CODE lt gt 01 GLUC EP 01 GLUC EP WL 505 STD 100 01 GLUC EP Insert BLANK 01 GLUC EP Blanking 01 GLUC EP Insert STD 01 GLUC EP Calibration FT 0 280 01 GLUC EP Insert SAMPLE 01 GLUC EP Sampling 01 GLUC EP mg dL 87 What You Do Response of RA 25 1 ENTER Press Select 505 filter and press ENTER Insert cuvette containing reagent into the cuvette well RA 25 sets to zero Insert cuvette containing reacted solution of standard into the cuvette well RA 25 performs calibration ENTER Pr
40. the Problem First Second Third Replacement Parts and Accessories Where to Order 5 6 5 7 5 8 5 9 5 10 6 1 6 3 6 5 6 7 6 10 6 12 6 13 6 15 6 16 7 1 7 2 7 3 7 4 9 3 9 4 Contents Cont 10 Technical Specifications Safety Notes Warranty Technical Specifications Safety Notes Warranty Manufacturer s Warranty Disclaimer of Warranties Limitations of Liability Warranty Service 10 1 10 2 10 3 10 4 10 4 10 4 10 4 10 4 1 Introduction General Description General Description This manual contains complete operating instructions for the RA 25 Chemistry Analyzer RA 25 Chemistry Analyzer The RA 25 Chemistry Analyzer is a compact programmable user friendly benchtop instrument It is designed to measure conveniently accurately and quickly different types of tests based on the following methods e Absorbance e Endpoint e Fixed Time e Kinetic e Enzyme Immunoassay e Immunoturbidimetric Assay e Drug Assay The RA 25 Chemistry Analyzer performs photometric measurements and calculates results according to preprogrammed parameters which are operator selectable through the keypad The RA 25 has five interference filters covering the range of 340 630 nm 340 405 505 546 630 nm The RA 25 has a test directory of 50 tests out of which any 25 test programs can be stored in memory The RA 25 is designed for round cuvettes of 12 mm O D outside diameter with 10 mm cuvette pathlength
41. umeric Liquid Crystal Display 2 Lines 16 characters each External 24 column Thermal Printer 8 bits 128 Bytes Data Storage 25 tests with parameters calibration factor and calibration curve in multistandard assay RS 232C For round 12 mm O D 10 mm cuvette pathlength 37 temp controlled 12 holes for 12 mm O D 10 mm cuvette pathlength 37 temp controlled Rechargeable built in Ni Cd battery pack Disposable 12 mm O D 10 mm pathlength Use only Bayer cuvettes Code No 9082 RA 25 Height 115 mm 4 5 inches Width 300 mm 11 8 inches Depth 321 mm 12 6 inches 5 4 kg 11 9 Ib Printer 45 mm 1 8 inches 132 mm 5 2 inches 151 mm 5 9 inches 0 4 kg 0 9 Ib 10 2 Safety Notes e instrument is designed for indoor use e Before switching on the power make sure the power source operating voltage and line voltage correspond e The power plug may only be plugged into a socket with a ground contact Do not use an extension cord with a nonfused grounded conductor e When opening covers or removing parts Exception you can do it manually the voltage carrying parts may lay open when the instrument is in the power on mode Connecting parts can also be under voltage e Disconnect the instrument from all voltage sources before performing maintenance procedures changing parts or making repairs or adjustments e Capacitors in the instrument can still be under voltage even if the instrument has been
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