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1. 28 KDS Model 410 Series Syringe Pumps TIL Specifications 5 43 2 1 9 8 7 6 As viewed from rear of the pump Pin 3 Vss ground ref 1 6 Controllable output with Programmable models could be used for relay or valve control low infusing high refilling 8 Trigger Falling edge starts stops pump eg Footswitch 4 Gate Change from high to low starts when running stays low change to high stops eg footswitch timer 2 Directional Output high infuse low refill stays high when stopped Undefined Input or Output Run Indicator high running low stopped 9 Reverse Direction Normally high connect to ground pin 3 reverses Direction only applies to infuse withdraw mode logic low 0 5V max 2ma current sink logic high 2V 5V Fuses The fuses are located in the power entry module on the rear panel The linecord must be removed first to gain access to the fuse holder Fuse Screw Driver Fuse Fuse Holder 5x20mm 250V 0 25 slow blow Fuse Replacement 29 KDS Model 410 Series Syringe Pumps Maintenance Maintenance is required only for the moving mechanical parts which should be kept clean and lubricated Occasionally a small amount of light machine oil should be applied to the guide rods and a small amount of grease or oil to the leadscrew Solvents of any type should never be used to clean the pump A mild detergent solution may be used to clean
2. Note A dispense volume must be entered before selecting W W I and CON modes mode Query mode Response I W I W CON dir rev Changes direction of running pump Available only in Infusion and Withdrawal modes dir Query direction Response I infusion or W withdrawal Not applicable in infusion only models error Command returns values from O to 7 as listed below O 7 no errors 7 serial error 2 stall 3 stall serial error 4 serial overrun 5 serial error serial overrun 6 stall serial overrun 7 stall serial error serial overrun 17 KDS Model 410 Series Syringe Pumps Operating Instructions Continued RS232 COMMANDS continued error Errors 8 15 only occur if using pressure switch 8 overpressure 9 serial error overpressure 10 stall overpressure 11 stall serial overrun overpressure 12 serial overrun overpressure 13 serial error serial overrun overpressure 14 stall serial overrun overpressure 15 stall serial error serial overrun overpressure Note sending query also clears all errors A serial error indicates a command that is too long for the input buffer A serial overrun indicates that a command has been sent before the prior command has been processed A stall error indicated that a stall condition has occurred Essential that after each command you must wait for the prompt indicating that the command has been executed before sen
3. that each step is saved done saves all programmed steps important that done is entered after all steps saved wait stops pump pauses but can be restarted continue restarts pump after wait command program continues nextstep causes program to jump to the next step mode query mode Response PGM activestep queries step running response where 1 to 8 25 KDS Model 410 Series Syringe Pumps Programmable Option 5232 Commands and Responses Continued timeleft number step time travel rateb ratef portout pause loops loop loopto loopent NOTE queries time remaining in active step response XX XX XX where hr min sec queries number of steps in program response n where n 1 to 8 queries step being programmed Not the active step response n where n 1 to 8 queries time in program step Not the active step response where hr min sec queries direction of travel in programmable step not active step response or W where is infusion and W is withdrawal Note Prompts gt or lt indicate direction of active step queries beginning rate response nnnnn uuu where nnnn is to 9uuu is ul m ul h ml m ml h sets finish rate response nnnnn uuu where nnnnn is O to 9 uuu are units ml m ml h queries status of output TTL pins 1 and 6 response HH HL LH LL queries whether pause response Y or N where Y is yes N
4. the keypad 30 KDS Model 410 Series Syringe Pumps 1 Air Tite All Plastic lec 50 4 70 mm 9 70 12 48 15 89 20 00 22 50 28 90 2 Becton Dickinson Interim WW design Plastipak lec 4 70 mm 3 8 59 5 11 99 10 14 48 20 19 05 30 21 59 60 26 60 3 Becton Dickson Glass all types 0 5 cc 4 64 mm 4 64 2 5 8 66 5 11 86 10 14 34 20 19 13 30 22 70 60 28 60 4 Hamilton 000 Series Gastight Oul 0 46 mm 25 0 73 50 1 03 00 1 46 250 2 30 500 3 26 ml 4 61 25 7 28 5 10 30 0 14 57 25 23 03 50 32 57 5 Popper amp Sons Inc Perfektum Glass 0 25 cc 0 5 1 2 3 5 10 20 30 50 6 2 7 Scientific Glass Engineering SGE 8 Sherwood Monojet Plastic cc 3 6 12 20 35 50 140 31 3 45 3 45 4 50 8 92 8 99 11 70 14 70 19 58 22 70 29 00 912 12 34 14 55 19 86 23 20 2760 0 73 1 03 1 46 2 30 3 26 4 61 728 10 30 14 57 4 65 8 94 12 70 15 90 20 40 23 80 26 60 38 40 9 Terumo lec 60 10 Unimetrics Series 9000 25 50 100 250 500 1000 4 73 9 00 13 04 15 79 2018 23 36 29 45 0 46 0 73 1 03 1 46 2 30 3 26 4 61 11 Stainless Steel KD Scientific 2 5ml 8 20 50 100 200 12 Nikepal Iml 2 5 10 20 30 50 100 150 4 790 9 53 19 13 28 60 34 90 44 755 4 80 mm 6 45 12 60 15 15 20 40 22 90 2745 35 90 34 20 KDS Model 410 Series
5. the product Do Not Operate with Suspected Failures If damage is suspected on or to the product do not operate the product Contact qualified service personnel to perform inspection Observe all Warning Labels on Product Read all labels on product to ensure proper usage CAUTION Protective Ground Refer to Manual Terminal CAUTION This pump is not registered with the FDA and is not for clinical use on human or veterinary patients It is intended for research use only CAUTION FOR RESEARCH USE ONLY NOT FOR CLINICAL USE ON PATIENTS KDS Model 410 Series Syringe Pumps General Description This manual applies to the KDSATO series infusion withdrawal pump Operation of the pump is simplified by using a keypad to select features from a menu on the alphanumeric display All control functions are performed automatically by the pump microcontroller and are based on the syringe diameter and linear motion of the pusher block to deliver a known volume After entering the syringe diameter either directly or from a table in memory a dispense volume and flow rate can be entered and then all calibration and control functions are performed by the pump automatically Features 1 Syringe identification Look up Table The pump contains a table of standard syringes arranged by manvfacturer material and size Once the syringe is identified in the table the pump automatically enters the appropriate diameter Direct Entry If the syr
6. 5 5 12 60 10 1515 20 20 40 30 22 90 50 27 45 100 35 90 150 34 20 KDS Model 410 Series Syringe Pumps Standard Minimum and Maximum Flow Rates Syringe size Diameter Minimum Maximum 10 ul 0 46 mm 0 001 21 10 25 yl 0 73 mm 0 003 ul hr 53 15 50 pil 1 03 mm 0 005 ul hr 105 8 100 pi 1 46 mm 0 009 ul hr 212 6 250 ul 2 3 mm 0 021 ul hr 527 6 500 ul 3 26 mm 0 042 ul hr 1060 1 ml 4 6 mm 0 083 ul hr 2119 2 5 ml 7 28 mm 0 207 ul hr 5286 3 ml 8 59 mm 0 288 7360 5 ml 10 3 mm 0 414 ul hr 634 ml hr 10 ml 14 57 mm 0 828 ul hr 1270 ml hr 20 ml 19 05 mm 1 414 ul hr 2171 ml hr 30 ml 21 59 mm 1 817 ul hr 2789 ml hr 50 ml 28 9 mm 3 277 ul hr 4998 ml hr 60 ml 26 6 mm 2 757 u hr 4234 ml hr 100 ml 34 9 mm 4 746 ul hr 7289 ml hr 140 ml 38 4 mm 5 746 ul hr 8824 ml hr Syringes from different manufacturers can have slightly different limits Note This is a reference diameter used to calculate the flow rate The specific diameter should be entered for your syringe type 33 KDS Model 410 Series Syringe Pumps Japanese Minimum and Maximum Flow Rates Available in Japanese Models Syringe size Diameter Minimum Maximum 10 ul 0 46 mm 0 001 ul hr 21 10 25 yl 0 73 mm 0 003 ul hr 53 15 50 ul 1 03 mm 0 005 ul hr 105 8 100 pi 1 46 mm 0 009 ul hr 212 6 250 ul 2 3 mm 0 021 ul hr 527 6 500 ul 3 2
7. 6 mm 0 042 ul hr 1060 1 ml 4 7 mm 0 087 yul hr 2703 2 5 ml 9 mm 0 323 ul hr 6259 3 ml 9 3 mm 0 337 ul hr 8626 5 ml 12 62 mm 0 7 ul hr 953 ml hr 10 ml 14 34 mm 0 802 ul hr 1230 ml hr 20 ml 19 68 mm 1 51 ul hr 2317 ml hr 30 ml 22 44 mm 1 963 ul hr 3013 ml hr 50 ml 28 8 mm 3 232 ul hr 4963 ml hr 60 ml 36 68 mm 5 243 yul hr 8051 ml hr Syringes from different manufacturers can have slightly different limits Note This is a reference diameter used to calculate the flow rate The specific diameter should be entered for your syringe type 34 KDS Model 410 Series Syringe Pumps Limited Warranty KD Scientific Inc warrants to the first consumer purchaser for a period of one year from the date of purchase that this unit when shipped in its original container will be free from defective workmanship and materials and agree that it will at its option either repair or replace the defective unit This warranty does not extend to misuse neglect or abuse normal wear and tear accident modification or unauthorised repair KD Scientific will not be liable or in any way responsible for any incidental or consequential economic or property damage Some States do not allow the exclusion of incidental or consequential damages so the above exclusion may not apply to yov There are no implied warranties of merchantability or fitness for a particular use or of any other nature Some atates do not allow th
8. MPER Maintenance Standard Table of Syringe Diameters seen 31 KDS Model 410 Series Syringe Pumps Japanese Table of Syringe Diameters 32 Standard Minimum and Maximum Flow Rates sss 33 Japanese Minimum and Maximum Flow Rates 34 limited Marrdnty e Ud beate 35 KDS Model 410 Series Syringe Pumps Specifications Model Syringe Size Electrical Rating Fuse Voltage Operating Range Drive Mechanism Pusher Advance Per Microstep Volume Per Microstep Stepping Rate Maximum Minimum Linear Travel Rate Maximum Minimum Flow Rate Range Nominal Linear Force Dimensions H x W x D Weight Atmospheric Specifications Temperature Humidity Mode of Operation Classification Pollution Degree Installation Category Output Physiological Effects Cooling Conditions Mechanical Stability Protective Packaging Earth Terminals Removable Protective Means Supplier Name Address 410 Series 10 microliter to 140 milliliter US model 115 0 25 A CE model 230 V 0 16 A 5 x 20 mm 250 Slow Blow 0 25 A US model 100 120 50 60 Hz CE model 200 240 50 60 Hz Microprocessor controlled stepper motor 1 2 to 1 16 microstepping driving a leadscrew through a belt and pulley drive mechanism 1 16 step 0 165 mm or 0 0000064 in 1 16 with 60 ml BD syringe 0 0919 1600 1 2 step se
9. Series Syringe Pumps Operating Instructions Continued MANUAL STALL SETTING AND MICROLITER SYRINGES Not recommended for small syringes A movable collar located on the rear guide rod of infusion only pumps can be set to limit travel of the pusher block The block moves until stalled against the collar when the electro optical sensor detects the stall and stops the pump Damage to the fine wire plungers of microliter syringes caused by forcing the plunger into the end of the syringe barrel can be prevented by careful adjustment of the collar position GLASS SYRINGES In the withdrawal mode the retaining bracket on the pusher block clamps on the head of the plunger With some glass syringes the corners of the plunger head are rounded and this may cause the head to ride up out of the retaining bracket Similarly in the infusion mode the rounded corners of the syringe barrel flange cause a tendency for the syringe barrel to ride up out of the syringe holder To give a more secure flatter surface to clamp against an O ring or metal collar can be placed over the barrel and pressed against the flange WARNING This version pump has enough force to break glass syringes and or bend thin plungers Stainless steel syringes should be used in this version pump Plastic syringes may be used but may fatigue under pressure KDS Model 410 Series Syringe Pumps Operating Instructions Continued CLEARING A STALL CONDITION Should a stall o
10. Syringe Pumps Japanese Table of Syringe Diameters Available in Japanese Models 1 Air Tite All Plastic lec 4 70 mm 2 5 9 70 5 0 12 48 10 15 89 20 20 00 30 22 50 50 28 90 2 Dickinson Interim WW design Plastipak lec 4 70 mm 3 8 59 5 11 99 10 14 48 20 19 05 30 21 59 60 26 60 3 Becton Dickson Glass all types 0 5 4 64 1 4 64 2 5 8 66 5 11 86 10 14 34 20 19 13 30 22 70 60 28 60 4 Hamilton 000 Series Gastight Oul 0 46 mm 25 0 73 50 1 03 00 1 46 250 2 30 500 3 26 4 61 2 5 728 5 10 30 0 14 57 25 23 03 50 32 57 5 JMC Air Tite pls Iml 4 66 mm 2 6 90 2 5 9 10 5 12 62 10 14 34 20 19 68 30 22 44 50 28 80 100 36 68 6 Nippro Iml short 06 61 Iml long 4 75 3 9 53 5 12 96 10 15 78 20 20 07 30 23 17 50 29 13 7 Hoshi 1 ml sm 4 80 mm Iml lg 6 70 2 mm sm 6 70 2 ml lg 9 20 4 10 30 5 12 20 10 15 00 20 19 00 30 22 50 50 25 50 100 34 00 8 Natsume 0 25 ml 2 60 mm 0 50 3 20 1 4 30 2 6 30 3 730 5 9 50 9 Iml 4 70 mm 2 6 40 3 9 30 6 13 10 12 15 40 25 21 00 30 23 00 50 29 00 32 10 Terumo Iml 4 73 mm 3 9 00 5 13 04 10 15 79 20 20 18 30 23 36 60 29 45 11 Terumo Japan sm 4 73 mm Iml lg 6 50 3 8 95 5 13 00 10 15 80 20 20 15 30 23 10 50 29 10 12 Stainless Steel KD Scientific 2 5 ml 4 790 mm 8 9 53 20 19 13 50 28 60 100 34 90 200 44 755 13 Nikepal Iml 4 80 mm 2 6 4
11. ace a Commands Address lt SP gt command lt CR gt lt LF gt b Response lt CR gt lt LF gt address lt NSP gt prompt For example Query pump 2 for withdrawal flow rate which is 0 2 ml minute command 2 lt SP gt ratew lt CR gt lt LF gt response 0 2 lt SP gt ml m lt CR gt lt LF gt 2 Query a single pump for infusion flow rate which is 0 2 ml minute command ratei lt CR gt lt LF gt response 0 2 lt SP gt ml m lt CR gt lt LF gt KDS Model 410 Series Syringe Pumps Operating Instructions Continued RS232 COMMANDS continued Prompts gt running in infusion direction lt withdrawing stopped NA not applicable E error see error command carriage return CR All pumps chain interpret this as a stop command pump address lt CR gt Pump with the specified address responds with a prompt pump address optional Pump at the address executes the command and then command lt CR gt responds with a prompt Note If there are multiple pumps in the daisy chain and a pump address is not used then all pumps will respond to the non specific command and return prompts Multiple prompts results in communications breakdown Pump commands and responses Note that mode selection and withdrawal and continuous mode commands are recognized only by the infusion withdrawal models run Starts pump running to present settings returns prompt gt or lt If already running command is ignored stop Stops pump if running o
12. ances RoHS Over time these Directives will be implemented in the national laws of each EU Member State Once the final national regulations have been put into place recycling will be offered for our products which are within the scope of the WEEE Directive Products falling under the scope of the WEEE Directive available for sale after August 13 2005 will be identified with a wheelie bin symbol Two Categories of products covered by the WEEE Directive are currently exempt from the RoHS Directive Category 8 medical devices with the exception of implanted or infected products and Category 9 monitoring and control instruments Most of our products fall into either Category 8 or 9 and are currently exempt from the RoHS Directive We will continue to monitor the application of the RoHS Directive to its products and will comply with any changes as they apply Do Not Dispose Product with Municipal Waste Special Collection Disposal Required
13. c 1 1 16 step 120 secs 12 67 cm min 4 95 x 10 cm hr 2 757 to 70 56 ml min 60 ml syringe 2100 lbs 15 x 28 x 24 cm 6 x 11 x 9 5 in 6 4 Kg 14 165 5 C 40 C 41 F 104 F 20 80 RH Continuous Class 2 I N A N A No special considerations special considerations special considerations External connections required N A KD Scientific Inc 84 October Hill Road Holliston MA 01746 1388 KDS Model 410 Series Syringe Pumps General Safety Summary Please read the following safety precautions to ensure proper use of your syringe pump avoid potential hazards and product damage use this product only as instructed in this manu al If the equipment is used in a manner not specified by the manufacturer the protection pro vided by the equipment may be impaired To Prevent Hazard or Injury Use Proper Line Cord Use only the line cord shipped with the product and make sure line cord is certified for coun try of use Ground the Product This product is grounded through the grounding conductor of the power cord To avoid electric shock use only approved line cord with the product and insure it is connected to earth ground Make Proper Connections Make sure all connections are made properly and securely Observe all Terminal Ratings Review the operating manual to learn the ratings on all connections Avoid Exposed Circuitry Do not touch any electronic circuitry inside of
14. ccur the pump motor is stopped to prevent damage To clear the display press select To move the stalled mechanism use the fast forward or fast reverse to move the pusher block Using the fast forward or fast reverse feature is not only the most simple way to deal with the stall it also reduces potential damage to the cam mechanism which releases the halfnut from the leadscrew NV Ram Failure If the settings in the non volatile memory become corrupted the display will read NV Ram Failure and the pump will not operate To recover from this condition the pump must be powered down and then turned on again after a few seconds delay The pump will be re initialized to the default settings and can now be programmed as normal If the above fails to work the Ram Failure message can also be cleared by pressing select and programming a new flow rate The pump should then be turned off and on to save the settings RS232C The RS232 connections are made through two modular telephone connectors labeled IN and OUT located on the rear panel A single PC can control up to 100 pumps via a daisy chain using the IN and OUT connectors When using the daisy chain each pump must be assigned an address and set to the same baud rate A splitter may be required with greater than 50 pumps When controlled via 85232 the pump will still respond to keypad commands but will not respond to keypad and RS232 commands simultaneously All RS232 command se
15. ction of travel for each step must be selected Initially Infusion direction will be flashing The direction keys gt and are used to switch between directions SELECT key is then used to load the direction into memory 5 Rate The program requires the initial rate Start the ending rate End and the units a Display reads Start xxxxx uuu is step number automatically assigned xxxxx is the numerical flowrate Enter from the numerical keypad uuu are flowrate units Use the arrow key to select units displayed flashing Repeat to move through the unit options Options are or ml m or ml h The 6 key is used to move back to the numerical display Press ENTER to save The menu now prompts for the final rate which is entered in the same manner b End xxxxx uuu numerical and uuu units of flowrate 21 KDS Model 410 Series Syringe Pumps Programmable Option Menu Operation Continued 8 Loop Continued b LOOP COUNT After setting the initial step number of the loop the menu will prompt for the loop count the number of times the loop will be repeated Maximum repeat number is 100 Display reads Loop Count x The number of loops to be executed x is entered from the numerical keypad followed by ENTER Note Maximum number of loops is two Once both loops are entered the loop option will NOT be displayed in menu b Changing Loops To change loops if two a
16. ding the next command Also the prompt will indicate that the command has been executed successfully or not prom Queries software version response is number 2100 0xx or 2101 or similar KDS Model 410 Series Syringe Pumps Programmable Option General Information KEYPAD PROGRAMMABLE PUMPS The program mode permits multistep dispenses without the need for computer control From the pump keypad a custom program can be entered which will control the pump from seconds to days permit the flowrate to be changed for discrete time periods repeat dispens es control output TTL signals to coordinate with other laboratory instruments or valves or respond to inputs from other devices such as switches or relays and to perform loops where dispense sequences are repeated The program is divided into time periods called STEPS each of which can be up to 12 hours long Each step is automatically numbered and to simplify programming a menu prompts the user to select the options available in each STEP The flowrate can be ramped up or down or kept constant for a defined time period for a volume dispense The initial and final flowrate for each period is entered and the pump automatically makes rate changes over the time period No need to enter increments for a ramp up or down the pump automatically ramps the rate linearly The pump can be paused and then restarted either by a time delay or by a TTL input Both TTL inputs and o
17. ditional commands and responses Each pump can be controlled either from the keypad or via RS232 at all times but the pump can only respond to one command at a time When under RS232 control the display reads REMOTE All settings made via RS232 are stored in non volatile memory To move the pump from Remote RS232 to keypad control press select Changes to program parameters cannot be made when the pump is running therefore parameter setting commands such as step travel rate etc are not applicable NA when the program is running When the pump is running all queries are disallowed except activestep timeleft and loops Commands not case sensitive After each command is received and executed the pump responds with prompt sequence a Query commands carriage return lt CR gt line feed text CR line feed 1 or 2 digit address prompt character b Other commands CR line feed 1 or 2 digit address prompt character Prompts gt running in infusion direction withdrawing stopped NA not applicable E error see error command P pump is paused carriage return CR All pumps chain interpret this as a stop command pump address CR Pump with the specified address responds with a prompt pump address optional Pump at the address executes the command and command CR then responds with a prompt Note If there are multiple pumps in the daisy chain and a pump address is not used then all pumps w
18. e Syringe Holder Block Rotate the Pusher Block Knob 7 until it snaps into place This will disengage the Pusher Block and allow the user to position the block to accept the syringe Place the syringe in the holder making sure the flange is resting against the Syringe Holder Block and the plunger is against the Pusher Block Make sure the plunger flange rests between the bracket and the pusher block and the syringe flange rests between the flange bracket and the syringe holder block for proper operation Rotate the Adjustable Clamp 2 until it rests on the Syringe barrel While pushing down on the Adjustable Clamp 2 tighten the T knob 1 KDS Model 410 Series Syringe Pumps Operating Instructions Continued SYRINGE LOADING Continued 8 Slide the Flange Bracket towards the Syringe Flange and tighten the T knobs 3 amp 4 9 Slide the Plunger Bracket towards the Pusher Block and tighten the T knobs 5 amp 6 10 Engage the Pusher Block by pulling the Knob 7 out and rotate the knob 90 clockwise 1 amp 2 Shoulder 5 amp 6 T Knob Screw 2 places Eun 2 places for for tightening the 8 V Clamp adjusting the V Clamp Plunger Knob Barrel Syringe Block Holder 3 amp 4 T Knob 2 places for adjusting the Flange Bracket Clamping for Stainless Steel Syringes Using the V Clamp for Stainless Syringes 1 Unscrew and remove the two Shoulder Screws 1 amp 2 and remove
19. he pump was previously used in Program Mode the pump will be initialized Program Mode when it is switched on For convenience it is possible to enter a new syringe size either from the stored Table or DIA without leaving the Program Mode Note If a syringe change is made this will change all program values to the default settings and will require reprogramming A diameter change causes the pump to stop resets the number of steps to 1 resets the activestep to 1 and all values will be set to the initial default settings The initialization of the new settings takes approximately two seconds Stall Condition The Fast Forward amp Fast Reverse features do not work in Program Mode Should a stall occur then go to Infusion Mode where the Fast Forward Fast Reverse features works and use these features to end the stall condition By going to the infusion mode the program is still saved in memory Changing programs containing loops Only two loops are permitted in a program and it is necessary to remove from memory the previously used programs which contain loops A convenient way to do this is to input a one step program which does not have a loop This way all loops are deleted from memory and the new program containing loops can be added 23 KDS Model 410 Series Syringe Pumps Programmable Option 5232 Commands and Responses All commands and responses in standard pumps remain the same however the program mode does have ad
20. ible to enter a new syringe size either from the stored Table or DIA without leaving the Program Mode If a syringe size change is made however this will change all program values to defaults and will require reprogramming It is possible to review the syringe size in Dia or Table without changing the pro grammed settings In Table review the settings but select QUIT do not enter a diameter In Dia the settings will not change if there is no change to the diameter entered MODE Mode selection reverts back to other pump operations STEP Step selection starts the programming sequence 20 KDS Model 410 Series Syringe Pumps Programmable Option Menu Operation After selecting MODE and then PROGRAM the display will show STEP which leads into edit ing the program 1 Number of STEPS Menu prompts NUM of Steps Enter total number of program steps using numerical keypad and press SELECT or ENTER to save a maximum of 8 2 Edit STEP The menu automatically increments the step number however it is possible to enter a different number If the step number displayed flashing is required then press SELECT to save and continue editing 3 Time Step Time xx xx xx Time xx xx xx in hours minutes and seconds Use the key to move from left to right and enter the time using the numerical keypad When the correct time is displayed press ENTER to load this time into memory 4 Infusion Withdraw The dire
21. ill respond to the non specific command and return prompts Multiple prompts results in communications breakdown Note that withdrawal and continuous mode commands are recognised only by the infusion withdrawal models 24 KDS Model 410 Series Syringe Pumps Programmable Option 5232 Commands and Responses Continued mode prgm sets pump in program mode Response number n sets number of steps in program n 1 8 stepn sets step number to be programmed n 1 8 time travel i w rateb nnnnn uuu ratef nnnnn uuu portout p important that step number be set before entering program settings sets time duration of step to be programmed hr min sec sets direction to infusion withdrawal sets step beginning rate where nnnnn is O to 9 where uuu are units ulm ulh mlm mlh Note if set rate is out of range then response is rate is set a zero sets step finish rate where nnnnn is O to 9 where uuu are units ulh mlm mlh Note if set rate is out of range then response is rate is set a zero sets status of output pins 1 and 6 where pis HH 1 high 6 high HL 1 high 6 low 1 6 high LL 1 low 6 low pause y orn sets status of pause y 7 active n inactive loop y orn sets loop status y 7 yes n no loopto n set step number to loop to where n 1 to 8 loopcnt b sets number of loops to be repeated where b 7 1 to 100 save saves step settings important
22. inge used is not included in the table the internal diameter of the syringe barrel can be measured in millimeters and entered directly from the keypad 2 INFUSION AND REFILL RATES The infusion rate and where applicable the withdrawal rate can be set independently and can be changed while the pump is running After the operating mode selection is made the program will prompt only for the relevant rates associated with that mode 3 VOLUME A target volume can be entered for infusion and refill independently and the pump automatically stops when this volume is reached The pump displays an initial volume of zero and increases as the dispense proceeds to the target volume The target volume can be reviewed or changed as the pump continues to operate KDS Model 410 Series Syringe Pumps Features continued 4 5 6 MODES OF OPERATION Infusion Rate and volume settings pump infuses to the set volume and stops Rate setting only pump runs until manually stopped or stalls Withdrawal Rate and volume settings similar to above Infusion withdrawal Infusion automatically followed by withdrawal Rate and volume settings can be made independently for infusion and withdrawal hence the pump can infuse at one rate and volume and then change to a different withdrawal flowrate and volume setting Withdrawal infusion Withdrawal immediately followed by infusion Separate settings for rate and volume can be made for withdrawal and infus
23. ion Continuous operation The pump cycles from infusion to withdrawal continuously The volume is identical in infuse and withdrawal directions Note The displayed menu which prompts the operator for Rate and Volume settings changes with Mode selection For convenience only the relevant settings associated with the selected mode are prompted For example in the Withdrawal Infusion mode the menu prompts for withdraw and then infuse volumes followed by withdraw and infuse rates In Infusion only mode the menu prompts only for infusion volume and infu sion rate In the Continuous mode only one volume is prompted for followed by infusion and withdrawal flow rates RS232C INTERFACE Multiple pumps can be controlled in a daisy chain by a single PC Programming is reduced to a small number of simple commands Input and output controls are available such as direction change run indicator footswitch or timer control and valve or relay actuation KDS Model 410 Series Syringe Pumps Features continued 7 8 9 10 11 STALL DETECTION The motor is monitored by optical encoder to confirm the programmed movement If the back pressure increases due to jamming or flow restriction then the motor may stall Stall detection by the encoder results in a pump shutdown The display will read Stalled The Stall message can be cleared with the Select key POWER DISRUPTION When power is returned after a tempora
24. is limitation on implied warranty so the above limitation may not apply to yov If a defect arises within the warranty period contact KD Scientific Inc see address below The customer is responsible for shipping charges and must first obtain a Return Material Authorization number RMA before the unit will be accepted If a replacement unit is issued it is covered only for the remainder of the original warranty period dating from the purchase of the original device This warranty gives you specific legal rights You may also have other rights which vary from state to state Note This pump is not registered with the FDA and is not for clinical use on human subjects Syringe pumps are manufactured by KD Scientific Inc 84 October Hill Road Holliston MA 01746 Phone 508 429 6809 Fax 508 893 0160 E mail info kdscientific com Web www kdscientific com kd Scientific Copyright 2005 KD Scientific Inc All rights reserved Printed in USA 35 WEEE RoHS Compliance Statement EU Directives WEEE and RoHS To Our Valued Customers We are committed to being a good corporate citizen As part of that commitment we strive to maintain an environmentally conscious manufacturing operation The European Union EU has enacted two Directives the first on product recycling Waste Electrical and Electronic Equipment WEEE and the second limiting the use of certain substances Restriction on the use of Hazardous Subst
25. is no queries whether loops in program response Sn x Sn x where Sn is the step number containing a loop x is the number of loops remaining to be executed counts down queries loop status in the step response Y or where Y is yes N is no queries step number to which program loops not available if no loops response n where n 1 to 7 queries number of loop repeats not available if no loops programmed response n where 1 to 100 a It is important to save each step before programming next step b Only two loops are permitted therefore recommend to query number of loops in an existing program before modifying the program If loops are present it will be necessary to delete an existing loop before a new loop can be programmed 26 KDS Model 410 Series Syringe Pumps Programmable Option 5232 Commands and Responses Continued PROGRAM EXAMPLE Syringe selected 4 70 mm diameter RS232 programming mode prgm Select Program mode Number 4 Sets number of steps in the program Step 1 Selects Step 1 for programming time 00 00 10 Step 1 time duration is 10 seconds travel 1 Infusion selected rateb O mlm Step 1 beginning rate is ml minute ratef 1 mlm Step 1 finishing rate is 1 ml minute portout hh Output pins 1 and 6 set at high high pause n Pause inactive loop n No loops save Save step settings Step 2 Ready to program step 2 time 00 00 15 Set time duration to 15 seconds rateb 1 mlm ratef 0 1 mlm b s
26. kd Scientific Model 410 Series Syringe Pumps User s Manual Publication 5605 001 REV D WEEE RoHS Compliance Statement EU Directives WEEE and RoHS To Our Valued Customers We are committed to being a good corporate citizen As part of that commitment we strive to maintain an environmentally conscious manufacturing operation The European Union EU has enacted two Directives the first on product recycling Waste Electrical and Electronic Equipment WEEE and the second limiting the use of certain substances Restriction on the use of Hazardous Substances RoHS Over time these Directives will be implemented in the national laws of each EU Member State Once the final national regulations have been put into place recycling will be offered for our products which are within the scope of the WEEE Directive Products falling under the scope of the WEEE Directive available for sale after August 13 2005 will be identified with a wheelie bin symbol Two Categories of products covered by the WEEE Directive are currently exempt from the RoHS Directive Category 8 medical devices with the exception of implanted or infected products and Category 9 monitoring and control instruments Most of our products fall into either Category 8 or 9 and are currently exempt from the RoHS Directive We will continue to monitor the application of the RoHS Directive to its products and will comply with any changes as they apply Do Not Dispose P
27. mp can resume operation select RUN or remain stopped select STOP If the pump resumes operation the rate display will flash to indicate that a power interruption has occurred Press select to clear the display to resume normal operation RUN STOP After all settings are made the pump can be started or stopped by a single press of the run stop key During a volume dispense the stop acts as a pause and run will resume the dispense KDS Model 410 Series Syringe Pumps Operating Instructions Continued CHANGE OR REVIEW VOLUME SETTING WHILE RUNNING While the pump continues to run press select to return to the main menu Scroll through the menu and select Volume to display the set dispense volume a No volume change Press select The display returns to the incrementing display volume b Volume change 1 Make the changes with the numerical keypad and enter 2 The display moves to RATE permitting a change if required Use the numerical keypad and enter to make changes or leave unchanged The pump immediately changes to the new flowrate if changed and the volume continues to increment uninterrupted by the review process to new target dispense volume when it will stop automatically Note If the volume is changed to a volume smaller than the volume already accumu lated then the pump will stop as soon as the new smaller target volume is entered MODE SELECTION Mode selection is available only on infusion withdrawal model
28. re already entered one loop must be cancelled before the new loop can be programmed c ALOOP within a LOOP It is possible to have a loop running within a loop 9 Saving the Step As there are many options in each step the program gives one more option Redo to make changes before storing the Step menu prompts Step Save Redo The arrow keys are used to highlight the required option which can be saved with ENTER or SELECT 10 Program End After saving the step the program prompts Next Step Done Next Step is selected unless all steps are completed and the above process is repeated for the number of steps required up to 8 When all steps are programmed Done should be entered with SELECT or ENTER to complete the programming The pump and display will now move to Step 1 ready to start the programmed dispense display reads xx xx xx gt 22 KDS Model 410 Series Syringe Pumps Programmable Option Running The Program Run The Run key starts the program the displayed time counts down and the direction arrow flashes Hold Continue If the Run Stop key is pressed while running a program the pump is stopped but gives an option to end the program or restart the pump and continue the program to its end Program changes when operating Once a step has commenced no changes are possible in that step However while dispensing changes are permitted to steps still to be executed Syringe size changes If t
29. roduct with Municipal Waste Special Collection Disposal Required KDS Model 410 Series Syringe Pumps Contents Specifications 3 General Safety Summary General cosh RR ERRARE AER EUR TERREA CHER t teret ES tUe Operating InstFUGtions POWER SWIG 7 Syringe Loading ettet tei ise reise te oreet 8 10 Withdrawal Operatiori ir tetro rente cebas 10 UniS SSiN ebrei bp i e He RO DEREN 11 Rate 11 POWOIEU 11 Run EE DOR URN Change or Review Volume Setting While Running Mode Selection tetto te eer uei eet itte Gases Infusion Withdrawal Infusion Withdrawal Withdrawal Infusion Continuous Manual Stall Setting and Microliter Syringes Glass a e Clearing a StallGondittoni 4 etre tierce tede 14 NV Ram Failure cesses 14 5232 0 5 S 14 R5232C Command Sareat e ta P n n LAE 15 18 Programmable Oplion zonis tte tt tme oe iseia ideios 19 27 General Information naso ine iaa a TNT 19 EIU e M 20 Men Operation 00 S 21 22 Ruining the d e Te ro BRE 23 Commands and Responses seen 24 27 RS232 Command eer 28 TTL Specifications QUI
30. ry power disruption the pump can be pro grammed to resume operation or remain stopped However if a dispense volume is set then the pump always remains stopped NON VOLATILE MEMORY All operational settings are stored in non volatile memory for convenience and are used to set the pump when first switched on SELECTION OF RATE AND VOLUME UNITS Units of volume or ml and flowrate per min hr can be changed if required POWER SAVER MODE When the pump is not running the unit goes into power saver mode This automatically prevents heat build up in the pump due to the motor being continually energized Operating Instructions POWER SWITCH The power switch is located in the middle of the rear panel KDS Model 410 Series Syringe Pumps Operating Instructions Continued SYRINGE LOADING 1 T Knob for securing the adjustable Clamp Rod Plunger Bracket 2 Adjustable Clamp 5 amp 6 T Knob 2 places for adjusting the Plunger Knob Pusher Block Syringe Holder Block 3 amp 4 Knob 2 places for adjusting the Flange Bracket Clamping for Plastic amp Glass Syringes Using the Adjustable Clamp for Plastic amp Glass Syringes Loosen knob 1 allows the user to lift and rotate the adjustable clamp 2 out of the way Loosen knobs 3 amp 4 and slide the Flange Bracket towards the Pusher Block Loosen knobs 5 amp 6 and move the Plunger Bracket towards th
31. s Select MODE from the main menu and then scroll through the options displayed and select the mode required Possible modes are infusion withdrawal infusion withdrawal withdrawal infusion continuous Note for bi directional modes a volume is required infusion Pump infuses at the set rate and stops automatically when the target volume is reached The pump can be manually stopped and restarted at any time that is the dispense is paused and when restarted will continue to the set dispense volume withdrawal Pump withdraws at the set rate to the set volume infusion withdrawal The pump first infuses and when the target volume is reached it immediately changes direction and withdraws The volume settings for infusion and withdrawal can be differ ent as can the infusion and withdrawal flow rates withdrawal infusion The pump runs first in the withdrawal direction and then automatically changes to the infu sion direction Different settings of rate and volume for withdraw and infuse are permitted continuous The pump first infuses and then withdraws and then cycles continuously Only one vol ume setting for infusion and withdrawal is permitted If the pump is matched to a valve which is actuated by a TTL pulse from the pump this mode can be used to infuse and then refill the pump for continuous operation The menu now prompts for volume and rate settings relevant to the mode selected 12 KDS Model 410
32. syringe plunger and barrel flange must be secured by the supplied brackets KDS Model 410 Series Syringe Pumps Operating Instructions Continued UNITS SETTING prompt Vol 00 00 ml lt The units displayed can be changed if required 1 Use the RIGHT arrow key to move the pulsing indicator to the units displayed 2 Continue to use the RIGHT arrow key to scroll through the possible units 3 The LEFT arrow key will move the active display back to the numerical value 4 When the correct value and units are displayed press enter Possible units are ul and ml microliter and milliliter and ml m ml h ml per minute or hour RATE SETTING Display reads Rate 00 01 ml h gt 1 Enter the flowrate value required with the numerical keypad 2 If necessary change the units using the key to move to and scroll through the possible units 3 When the displayed settings are correct press enter Note If the number entered exceeds the maximum flow rate possible then the pump displays the maximum feasible rate To continue enter a rate smaller than the maximum Note To check the maximum possible rate enter 9 s to the required decimal position For example enter 99 9 and the maximum displayed is 12 3 whereas if 99 99 is entered then the maximum displayed is 12 34 POWER UP run or stop This option is only applicable when no dispense volume is selected When power returns after an interruption the pu
33. tep 3 portout step 1 ratef Assumes previous travel direction infusion and sets step 2 beginning rate 1 ml minute Finishing rate O 1 ml minute loop y Select a loop loopto 1 Program will loop back to step 1 after completeing step 2 loopent 1 Will repeat the loop one time save step 3 Ready to program step 3 time 00 00 20 Time of step 3 is 20 seconds rateb 3 mlm Sets begin rate to 0 3 ml min Assumes no direction change ratef Sets finish rate to ml min save Step 4 Program step 4 time 00 00 12 Time duration 12 seconds travel w Change direction to withdrawal rateb 1 mlm Withdraw rate set to 1 0 ml minute ratef 1 mlm Finish rate 1 ml min loop y Select a loop loopto 3 After step 4 will loop back to and repeat step 3 loopent 1 Will repeat loop one time save done completes and saves program Queries loops 52 1 54 1 loop in step 2 loop count is 1 loop in step 4 count 1 Portout set in step 1 and remained unchanged Finish rate in step 1 is 1 0 ml minute 27 1 ml m KDS Model 410 Series Syringe Pumps RS232 COMMANDS RS232 Format 8 data bits No parity 1 stop can use 2 stops Pump uses simple three wire communications ground transmit and receive No flow control No handshaking Ground Ground Ground Ground Receive Receive Transmit Transmit OUT IN PC with 9 pin connector PC with 25 pin connector data pin 2 data OUT pin 2 data OUT pin 3 data IN pin 3 ground pin 5 ground pin 7
34. the V clamp 8 2 Loosen the two T knobs 3 amp 4 and slide the Flange Bracket towards the Pusher Block 3 Loosen the T knobs 5 amp 6 and slide the Plunger Bracket towards the Syringe Holder Block 4 the Pusher Block by rotating the Plunger Knob 7 until it snaps into place KDS Model 410 Series Syringe Pumps Operating Instructions Continued SYRINGE LOADING Continued 5 Place the syringe in the holder and place the V Clamp 8 inverted over the barrel of the syringe and replace the Shoulder Screws 1 amp 2 Tighten the Shoulder screws Make sure the flange of the syringe is resting against the Syringe holder block between the clamp and the Syringe Block and the Plunger Flange is between the Pusher Bracket and the Pusher Block 6 Slide the Flange Bracket towards the Syringe Flange and tighten the two Knobs 3 amp 4 7 Slide the Plunger Bracket towards the Syringe Plunger and the Pusher Block and tighten the two T knobs 5 amp 6 8 Engage the Pusher Block by pulling the Plunger Knob 7 out and rotate the knob 90 clockwise To simplify syringe loading the pusher block can be disengaged from the leadscrew by turn ing the knob 7 and manually moved along the guide rods Alternately the Fast forward Fast reverse feature can be used press Run and respective Arrow key simultaneously 5410 WITHDRAWAL OPERATION For withdrawal or refill operation the
35. therwise is ignored Returns prompt dia nn nn Sets syringe diameter in millimeters n 0t09 run Query run status returns prompt del Gueries delivered volume Requires a dispense volume to be set Response lt 5 gt Where nnnnn is O to 9 u are units or ml dia Requests present diameter setting Response nn nn Where n 0109 units always millimeters ratei Queries infusion rate Response nnnnn lt SP gt u u Where nnnnn is O to 9 are units ml m or ml h ratew Queries withdrawal rate Response nnnnn lt SP gt u u Where nnnnn 5 Oto 9 is rate unit 16 KDS Model 410 Series Syringe Pumps Operating Instructions Continued RS232 COMMANDS continued ratei nnnnn u u Sets infusion rate Where is nnnnn is O to 9 and u u are units Units required but if not specified then defaults to automatic setting based on syringe diameter ratew nnnnn u u Sets withdrawal rate voli nnnnn uu Sets infusion target volume Where nnnnn is O t0 9 uu are units or ml If units not specified then defaults to automatic setting volw nnnnn uu Sets withdrawal target volume voli Queries volume setting Response nnnnn lt SP gt uu Where nnnnn is O to 9 uu are units and ml mode Sets mode to infusion mode w Sets mode to withdrawal mode l w Sets mode to infusion withdrawal mode w l Sets mode to withdrawal infusion mode con Sets mode to continuous
36. ttings similar to keypad settings are stored in non volatile memory Select RS232 from the main menu Baud Rate 300 1200 2400 4800 9600 The available baud rates will now be displayed and can be selected using the arrow and select keys The display now prompts for assignment of a pump address Address If no address is assigned then the pump defaults to a setting All pumps with the same address respond simultaneously to the same commands Use the key to enter an address 99 and press select to return to the main menu 14 KDS Model 410 Series Syringe Pumps Operating Instructions Continued RS232 COMMANDS RS232 is used for remote computer control of up to 100 pumps identified with an address from O to 99 and set to the correct baud rate Each pump can be controlled either from the keypad or via RS232 at all times but the pump can only respond to one command at a time When under RS232 control the display reads REMOTE All settings made via 85232 are stored in non volatile memory To move the pump from Remote RS232 to keypad control press select After each command is received and executed by the pump the pump responds with a mes sage and a prompt Commands and Responses Commands are not case sensitive After each command is received and executed the pump responds with prompt sequence abbreviations lt CR gt carriage return lt LF gt line feed lt SP gt space lt NSP gt no sp
37. utputs can be controlled by the pump The pump can therefore respond to switch closures or send out signals to actuate valve or other relays switches etc Two separate loops can be programmed so that steps can be repeated The number of repeat operations is controlled by the loop count For example this is helpful when a volume dispense is required repeatedly triggered by a switch The two loops can be nested so that the program can run for days and complex dispenses can be repeated many times KDS Model 410 Series Syringe Pumps Programmable Option Features PARAMETERS WHICH CAN BE PROGRAMMED IN EACH STEP Time duration Infuse or withdraw Start flowrate End flowrate output settings Pause wait for TTL input actuation Loops to repeat previous steps To simplify the programming previously programmed settings are stored in non volatile memory and are displayed when Program Mode is selected Whenever possible options are displayed with the active option flashing If flashing this parameter can be selected or changed The pump can be programmed by first selecting MODE on the mainline menu and then selecting Program DISPLAY AND PROGRAMMING SEQUENCE After selecting Program Mode display reads Table Dia Step Mode DIA and TABLE If the pump was previously used in Program Mode the pump will be initialized in Program Mode when it is switched on For convenience should a syringe change be required it is poss

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