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1. Select the mode of conveyer movement e Select the Continuous mode with a tick e Enter the value of Conveyer speed in cm sec As a result the packages with irradiated materials will continuously move on a conveyer platform in parallel with surface of source rack from first point of the Left part of irradiation field to the last point of the Right part of irradiation field with selected Conveyer speed See Fig 2 12 First point of the Left part of irradiation field see point A on Fig 2 characterize the entrance into gamma radiation field into irradiation room of front face of packing box in direction of conveyer movement Last point of the Right part of irradiation field see point C on Fig 2 characterize the exit out gamma radiation field out of irradiation room of back side of packing box in direction of conveyer movement e Select the Discrete mode with a tick e Enter the value of Number of positions e Enter the value of Dwell time in sec As a result the packages with material will discretely move on a conveyer platform step by step from first point of the Left part of irradiation field to the last point of the Right part of irradiation field The Number of positions characterize the number of rest for the container with product on the distance between first point of the Left part of irradiation field to the last point of the Right
2. e Dosimetry module is intended for preparing of experimental data This tools allows to load data files invert and move each experimental curve cut and scale transform to format of Comparison module For work with software ModeGk e Click the File then Open configuration then to select irradiating system and load the file Test rts e Again click the File then Open configuration then to select irradiated target and load the file Test rtt After loading the Test rts and Test rtt files user can change all characteristics of Gamma ray facility and irradiated target for simulation Gamma ray processing If all input data are saved color of the scheme changes to blue e Enter the Number of trajectories and e Click the button Simulation In time simulation the Software ModeGR shows Starting time and defines time required for calculation e Click Stop to interrupt your calculation and reenter data e When MC simulation will be finished the button View results after simulation will be active e Click the button View results after simulation and work with results 1 Geometrical model of Gamma ray facility and irradiated target Source Rack Cobalt 60 aa absent sourse pencils pencils pensils eens EN BEE ck TH Bm Source Modules Target b G D ees veers c h H A wo B C Travel Fig 2 Geometrical arrangement of Co pencils four source modules
3. 2D registration will be opened See Fig 23 Note 1 On all curves of 2D dose distributions of Gamma ray in any target positions on a conveyer platform the dose value is the function of layer width axis X Note 2 On all curves of 2D dose distributions of Gamma ray in any target position on a conveyer platform the dose value is integrated along layer thickness axis Z e Additional information related to Gamma ray absorbed dose distributions are presented in this form e Average dose Dose minimum e Dose maximum 23 e Statistical uncertainty e Joined cells for centre and for boundary Store all results to file Show input data Show 3D results reaala Dose package 1 layer 1 package 1 T Center Boundary layer 1 1 2 i _ tw Se eee nngqossnannposssnngqosnnnns To eseesesfeesees ede eees s Migs fe ee de ee eee nm ee te ee EEEE a CEET ee ee ee ee ee eee Ta o o ONS Ja ETETETT EEETEEEEECTTETETELTEETEETETEITETTEET ao O GE ag Nw hw Scaled energy deposition dose Fs Scaled energy deposition dos o4 0 02 04 06 06 1 Ue 04 06 0a 1 Scaled width Scaled width Scaling Dose 0 00214 kGy Scaling X 20 cm Scaling Dose 0 002292 kGy Scaling X 20 cm Width Dose a DUR 2 114 Width Dose a DUR 2 083 24 0 002098 __ O 0 002257 3 Average dose 0 001749 Average dose 0 001875 2 8 0 002098 04 0 002257 0
4. 6 gt 1 000 9 gt 2 000 10 gt 20 000 11 gt 40 000 12 gt 4 000 13 gt 50 000 1 4 gt 10 000 15 gt 30 000 16 gt 100 000 1 7 gt 50 000 16 gt 100 000 19 gt 30 000 20 gt 50 000 Pencils activity of 2 module N activity Pencils activity of 2 module N activity 1 gt 0 000 2 gt 0 000 3 gt 0 000 4 gt 0 000 5 gt 0 000 6 gt 0 000 gt 0 000 8 gt 0 000 9 gt 0 000 10 gt 0 000 11 gt 0 000 12 gt 0 000 13 gt 0 000 1 4 gt 0 000 15 gt 0 000 16 gt 0 000 1 gt 0 000 18 gt 0 000 19 gt 0 000 20 gt 0 000 Pencils activity of 3 module N activity Pencils activity of 3 module N activity 1 gt 0 000 2 gt 0 000 3 gt 0 000 4 gt 0 000 5 gt 0 000 6 gt 0 000 gt 0 000 8 gt 0 000 9 gt 0 000 10 gt 0 000 11 gt 0 000 12 gt 0 000 13 gt 0 000 1 4 gt 0 000 15 gt 0 000 16 gt 0 000 17 gt 0 000 v 18 gt 0 000 19 gt 0 000 20 gt 0 000 Configuration data 16 gt 0 000 19 gt 0 000 20 gt 0 000 Pencils activity of 4 module N activity Pencils activity of 4 module N activity 1 gt 0 000 2 gt 0 000 3 gt 0 000 4 gt 0 000 5 gt 0 000 6 gt 0 000 7 gt 0 000 8 gt 0 000 9 gt 0 000 10 gt 0 000 11 gt 0 000 12 gt 0 000 13 gt 0 000 14 gt 0 000 15 gt 0 000 16 gt 0 000 1 gt 0 000 16 gt 0 000 19 gt 0 000 20 gt 0 000 Irradiated volume Packages
5. Vertical Normal displacement Vertical Turn on 90 degree Z Packing Packing Box Box Conveyer Scan Conveyer Scan platform lt platform Target Target E E Onn a z Packing Packing m Box aa Fig 14 1 Fig 14 2 Figs 14 1 and 14 2 Some possible orientation positions on a conveyer platform for package of flat layers placed in open packing box Switch position 1 Switch position 2 Vertical Normal displacement Vertical Turn on 90 degree emnt WAY Packing Packing haa Conveyer a Sn _ Conveyer a Sn platform platform Target Target E E p b 2 b m T Packing Packing Box Box Add Cover Add Cover Fig 15 1 Fig 15 2 Figs 15 1 and 15 2 Some possible orientation positions on a conveyer platform for package of flat layers placed in open packing box with additional cover and corresponding switch positions 19 6 Input data for irradiation of some identical Multi layer targets with without packing box Simulation of the dose distribution in the Several identical Multi layer targets with without packing box allows to investigate the mutual influence of the nearest neighbor boxes on an Gamma ray absorbed dose formation in the target layers See Fig 11 e Click the window Multi target with a tick See Figs 2 5 and 16 e Enter the value Distance between targets in cm The distance between boxes with Multi layer targets can be gt 0 Il Multi
6. 00214 0 002292 2 8 0 002114 iia Lie 0 4 0 002239 Dose max 3 2 0 002114 Dose min 0 001012 oe 0002230 Deen oomi Prepare 3 2 0 00214 Joined cells 2 0 8 0 002203 Joined cells 1 data 3 6 0 00214 for center 1 2 0 002203 for boundary to calculate Thickness cm calc error for center calc error for boundary SAL 10 1 04 0 9772 V idth in cem Dose in KGY Fig 23 Form with 2D view of the depth dose distribution of Gamma ray in graphical and tabular forms for the 1 layer in the 1 package Left graph 2D view of the depth dose distribution in the Centre of the 1 layer in the 1 package Le in the area Length 2 Right graphs 2D view of the dose distribution near the Boundary of the 1 layer with Air in plane XZ blue curve for first XZ plane in direction of conveyer motion violet curve for the back XZ plane in direction of conveyer motion e Click on any package _P_ and any layer _L_ number in the Table 2D registration the 2D depth dose distributions for corresponding package and layer will be appear in the form In this way you can see step by step the 2D depth dose distributions for all selected packages and layers in the Table 2D registration e Click the button Store all results to file the results simulation in graphical and tabular forms will be stored for further analysis e To processing simulation results previously stored in the files Click the button Open and view
7. 60 slugs encapsulated into stainless steel capsule and ea blank inactive stainless steel cylinder The source pencil construction is presented in Fig 6 All pencils types have the same geometrical characteristics End cap Source pencil Cobalt cylinder Fig 6 Source pencil construction e Enter the value of the radius and height of cobalt slugs in cm e Enter the value of the radius and height of end cap in cm e Enter the value of the radius of capsule in cm e Enter the value of the distance between axes of adjacent pencils in cm 3 2 Input data of source modules and sorce rack Typical source modules manufactured by firm MDS Nordian Canada comprises 40 48 of the above cobalt 60 source pencils The model of source module with pencils arrangement is presented in Fig 7 In this model the number of pencils in the source module can be in the range from 0 to 200 It is allows one source module to present reconstruct simulate as 1 5 typical source modules As a result we can represent source rack with 20 typical source modules in 2 x 10 array Cobult 60 blank absent source pencils pensils pencils yi 4 ft Js ft ft p Fig 7 Scheme of arrangement of sours pencils in the source module 10 The schematic model of the panoramic source rack with arrangement of four source modules is presented in Fig 8 Source Rack Cobalt 60 a absent sourse pencils ak ca pensils Sou
8. Example Configuration data for simulation of Gamma ray dose distribution in an irradiated target The Main form of the Software ModeGkR is presented in Fig 19 Example of target parameters data for which simulation and preparation of output data will be made is presented in Fig 20 Position of target on a conveyer platform is presented in Fig 21 Full configuration data which are used under simulation are presented in Fig 22 23 fi Target and cover ModeGR 1 1 2008 CE Fie Options Help About Number of packages Multi Target Orientation Along the scanning axis Normal displacement 6 w Vertical o Along the conveyor axis l Turn on 50 deg f ModeG A Width ot Mi i E packages t Current layer 3 Delete Insert Clear a 100000000 21 p Layer 2 3 4 5 5 q Thickness 10 15 12 Stack length width 20 20 10 20 Density 1 15 14 1 3 20 registration Polyethylene Z wi Z wit zZ un Yu z iy E yt Simulation package layer Poliystyrene Ww 3 6 4 4 2 PRAM THe 50 G 12 Carbon 8 29 dd Birchwood 20 41 11 Cellulose e 3 start 19 55 14 3 finished 70 01 00 2 5 W SD calculation Open and view results from file Smeaton Density 27 Carbon iw List Opened cover Birchwood Cellulose Cover thickness of Sai Tine m Water A number W part k a Additional cover o Tailan Rows Ee pa i Comparison ackage EVE aaa Dosimetry F 4 Another material iy hdonte
9. Target Distance E between targets Fig 16 The form for entering of input data for Multi target 7 Input data for Table 2D registration 2D registration The Table 2D registration allows to select the number of package level packages and the number of layers for which the results of simulation for absorbed dose distribution ADD will be presented in the 2D graphical and tabular forms See Figs 2 and 17 iM 30 calculation J registration package level P L Fig 17 The form for entering of input data for 1 3 Table 2D registration and 3D registration e Select in the Table 2D Registration the number of packages and the number of layers in selected package for which the results of simulation for absorbed dose distribution ADD will be presented in graphical and tabular forms e Note The Table 2D Registration includes the number of packages P and the number of layers L in selected package P 20 e For one run simulation the number of packages P can be selected in the range from 1 to 6 of 10 packages and the number of layers in selected package L can be selected in the range from 1 to 6 e For obtaining of the values for ADD in another packages and layers you need to enter the number of appropriate packages and layers in the Table 2D Registration and repeat the run simulation In this way you can obtain step by step the ADD in all layers of multilayer target 8 Input data for T
10. part of irradiation field The Dwell time is the time interval during which a process load is at rest at an irradiation position 4 Target 4 1 The form for entering of input data for irradiated Target and Cover e Click Target in the Main form of the Software ModeGR See Fig 1 The form for entering of input data for irradiated Target and Cover Container materials will be opened See Fig 9 f Target and cover ModeGR 1 1 2008 Number of packages Multi Target TEn C Along the scanning axis Normal displacement e vertical Along the conveyor axis Turn on 90 deg idth of packages t Current layer 3 Delete Insert Clear a 21 r Layer 1 2 4 5 6 g Thickness 10 15 T2 Stack length Width 20 20 10 20 t Density 1 15 44 2D reqistration Polyethylene ia package layer Poliystyrene Phinda a Carbon Birchwood Cellulose ae M C Density 2 7 Carbon v List Opened cover bail 0 Birchwood E Table Y Cellulose V 3D calculation Cover thickness 0 1 Soft Tissue e 3D reqistration r e Water Rows Anumber W part Additional cover 0 Teflon package level reer m 13 4 Sna ee Iron E 4 4 Another material v Thickness width additional cover cm Density q cm3 Save data and close this window Fig 9 The form for entering of input data for irradiated Target and Container materials Cover 13 4 2 Multi layer target model e M
11. three parts accordingly with scheme near the button Calculation e Click the button Calculation The integral of function pdf for the three parts divided Markers will be appeared in the right downside of the Dose map form See Fig 25 Right part f Dose map for package 1 layer 1 ModeGR 1 1 2008 0 i 0 001 0 0012 0 0014 0 0016 0 0018 0 002 0 0022 Dose kGy pdf probability density function 1 KGy cdf cumulative distribution function Probability Marker Scaling Dose 0 002235 kGy 0 00221 0 002 Layer width em 20 0 00 21 81741 0 002173 0 El 0 00 196 35670 _Marker2 Length cm 20 0 002144 0 002 E 4 0 00 294 53500 0 002144 0 002 z i pennies 0 00 483 61920 verage dose 0 002128 000 J a 0 00 501 80040 Dnin Snak Effecti 0 5791 0 002122 0 002 ERO 9 00 541 70900 DUR 2 440654 Dose Uniformity Ratio 2 168 am gt y 0 00 60361480 Average dose 0 001780 Figure to clipboard a 3D 2D Figure s turn Salses ae seai nn 3 0 015000 From 0 00 From 0 00 From 0 00 Data to clipboard amA Figure sight To 0 00 To 0 00 To 0 00 Fig 25 Results of the Dose Volume Histogram analysis In a such way you can made DVH analysis step by step for each of six selected for calculation layers see Registration Table P and _L_ in Fig 17 e Additional information related to 3D view of an absorbed dose distribution in the selected layer are prese
12. 26 946325 s u gt Spoke along X axis Y value 1 100 50 Spoke along Y axis Z value 1 400 50 Spoke along Z axis Current curve 3 With current cure With all curves Add curve Normalizing Save data Fig 26 The form of Results of 3D calculation for analysis of the DVH and the 3D absorbed dose distributions in the 1 layer of the 1 package Additional you can made the detailed DVH analysis for each volumetric part in the 1 layer of the 1 package For this purpose Select the coordinates of interesting volumetric part of the layer The frame for selection the coordinates of interesting volumetric part in form of tables Start points and Length is located in the left down part of the frame Results of 3D calculation See Fig 26 e Enter the values of X Y and Z coordinates in the table Start points in cm e Enter the values of X Y and Z coordinates in the table Length in cm 29 e Click the button Cut and recalculate e Then with help the Marker 1 and Marker 2 you can carry out DVH calculation for selected volumetric part of the layer e In a such way you can made DVH analysis step by step for another interesting volumetric part of the layer 10 4 2 3D absorbed dose distribution analysis 3D absorbed dose distribution of Gamma ray for any target layers can be analysed with spokes method The method includes the following operations e the laye
13. 6 Layers in each package 1 Width of packages 21 000 Stack length 20 000 Distance between targets 0 100 Vertical target orientation Normal target displacement Layer Thickness Width Density 1 10 0000 20 0000 1 0000 Layer2 V 1 6 0000 1 0000 Covering of irradiated volume Cover thickness 0 200 Cover density 1 000 Additional cover 0 000 Closed cover Yes CZ 6 1 The following package and layer were registrated in gotten 2D results P 1 L 1 P 2 L 1 P 3 L 1 P 4 L 1 P 5 L 1 P 6 L 1 The following package and layer were registrated in gotten 3D results Package 1 Layer 1 Options of the calculation Energy cut off Mev 0 100 Threshold energy Mev 0 200 Number of joined cells for center 2 Number of joined cells for boundary 1 Splitting on 7 2 100 100 100 Angle grouping 0 050 Calculation mode is normal Normal coordinate system D Calculated options without scattering from vault v Lill Fig 22 Full set of configuration data which is used at simulation of an Gamma ray absorbed dose distribution 10 2 Output Data for 2D dose distributions e After finish Simulation Click the button View results after simulation in the Main form of the Software ModeGR see Fig 19 The form Dose distributions after MC simulation with 2D absorbed dose distributions in graphical and tabular forms for selected packages and layers in the Table
14. Carlo successtuled Se SS Thickness width additional cover cm Density icma Save data and close this window Fig 19 Main form Fig 20 Example of Multilayer target of the Software ModeGR Switch position 1 Switch position 2 Vertical Normal displacement Vertical Turn on 90 degree Z Z Packing Packing Box Box Conveyer Scan Conveyer Scan platform platform Target Target E b O Packi acking Packing Box Box Fig 21 Target positions on a conveyer platform 24 Configuration data ModeGR Modelling of an irradiation of packages by Gamma ray Source of Gamma Ray Number of pencils 20 p Radius cobalt cylinder 0 500 Height cobalt cylinder 20 000 Radius end cap 0 700 Radius end cap 0 700 Radius of stainless steel cladding 0 550 Distance between cylinders axes 1 500 Distance x between source and packages 5 000 Distance Y between source and packages 20 000 4 Distance X between modules 2 500 Distance Y between modules 2 500 7 Distance x between modules 2 500 Distance Y between modules 2 500 Left part of irradiation field 1000 000 Right part of irradiation field 1000 000 Continuous irradiation mode Speed of conveyor moving 1 000 Pencils activity of 1 module N activity Pencils activity of 1 module N activity 1 gt 20 000 2 gt 30 000 3 gt 4 000 4 gt 2 000 5 gt 2 000 6 gt 60 000 gt 50 000
15. Select Module with a big number of blank or absent pencils For do it Click the number of selected Module 1 2 3 or 4 in down part of frame with source rack characteristics See Fig 5 middle part e Enter the values of Activity in Ci only to each active source pencils in the table of selected Module e Select 0 or 1 in the window located near the button Fill activity table e Click the button Fill activity table As a result all empty rows in the selected Module will be filled with value 0 or Hil 3 3 Input data of source rack and target arrangement e Enter the value of the Distance Z source packages in cm e Enter the value of the Distance Y source packages in cm Distance Z source packages characterize the distance between planar surface of irradiator and frontal face of the product container Distance Y source packages characterize the displacement of bottom part of the product container relatively axis X See Fig 5 Default mode characterize the location of the product container in a such position that center of the container in direction of axis Y is equal position Y 0 e Enter the value of the Left part of irradiation field in cm Left part of irradiation field characterize the distance AB in Fig 2 e Enter the value of the Right part of irradiation field in cm Right part of irradiation field characterize the distance BC in Fig 2
16. Software ModeGR for Quality Control of Gamma Ray Processing User Manual Software ModeGR Modeling of 3D Gamma dose distribution with MC method The program ModeGR was designed specially for simulation of the absorbed dose distribution within multi layer packages irradiated with gamma ray from flat panoramic Co source rack The Co source rack can be represented as a rectangular planar frame with number of modules from 4 up to 20 which should be mounted in two levels with uniform non uniform distribution of Co strength The product on a conveyer platform can be irradiated in two modes e continuous mode the container with product will continuously move on a conveyer platform in parallel with surface of source rack e shuffle dwell mode the container with product will discontinuously move on a conveyer platform in parallel with surface of source rack to a new irradiation position and then remaining at rest for a dwell time at that position Where the dwell time is the time interval during which a process load is at rest at an irradiation position Irradiated product can be represented in form of container with homogeneous materials as well as of container with stack of plates The stack of plates can be interleaved with dosimetric films A source of gamma rays a conveyor line an irradiated product and a package are considered in uniform self consistent geometrical and physical models Differential and integrated characteristics
17. able 3D registration The Table 3D registration allows to select the number of one of packages and the number of one of layers in the selected package for which the results of simulation for analysis of the 3D absorbed dose distribution ADD of Gamma ray will be presented in the graphical and tabular forms See Figs 2 and 17 e Tick the window 3D calculation See Figs 2 and 17 e Select in the Table 3D registration the number of package P and the number of layer L in the selected package P for which the results of simulation will be available for analysis of 3D absorbed dose distribution ADD in graphical and tabular forms e For obtaining of the values for 3D ADD in another packages and layers you need to enter the number of appropriate package and layer in the Table 3D registration and repeat the run simulation In this way you can made analysis of the 3D ADD of Gamma ray step by step in all layers of multilayer target At the end Click Save data and close this windows The selected parameters for multilayer target will be saved and ready for simulation 9 Options Options are intended for e optimization of simulation regimes optimization of parameters visualization of calculated results e scientific research of transport irradiation through heterogeneous targets Options includes tree thematic parts e Expert modes of simulation Normal Without scattering and Scattering fro
18. are working in an optimal automatic regimes which were installed in the physical operational and in calculation models of the Software See Fig 18a All parameters of Options can be changed only in regime Manual parameters See Fig 18 b 9 1 Expert modes of simulation Normal Without scattering and Scattering from vault Mode simulation Normal It is standard regime with automatic choice of the parameters simulation such as Photon energy cut off Normal mode characterise the full MC scheme which includes simulation e transport of Gamma ray beam in an irradiated target with taking into consideration the scattering effects of photons Without scattering mode characterise MC scheme which includes e MC simulation the transport of Gamma ray in an irradiated target without taking into consideration the scattering effects for photons Such MC simulation is equivalent so called point kernel method without taking into consideration of the build up factor Scattering from vault mode takes into consideration additional to the Normal mode the contribution into absorbed dose of scattering photons from targets located in the opposite side of source rack 22 9 2 Parameters of visualization of results 1 Joined cells for center and boundary define the number of cells which were combined in the Center or Boundary of irradiated layer at calculation and visualization of 2D dose distrib
19. conveyer and containers with product The Co source rack can be represented as a rectangular planar frame with number of modules from 4 up to 20 which should be mounted in two levels with uniform non uniform distribution of Co strength Geometrical models of multi layer targets 1st 2nd additional package package packing b i Multilayer closed Multilayer Multilayer hi target targe ey target packing box closed closed packing box packing box Helles Hell al Hat Conveyer Xx LY Conveyer X LY Fig 3 1 Geometrical models of multi layer targets on moving conveyer irradiated with Gamma ray Conveyer moves along axis X a Multi layer target consists of two 6 layer packages placed in closed packing box b Multi layer target consists of 6 layer package placed in closed packing box with additional packing materials c multi layer targets irradiated with Gamma ray in parallel with interface of contacting materials 6 Irradiated product can be represented in form of container with homogeneous materials as well as of container with stack of plates The stack of plates can be interleaved with dosimetric films The product on a conveyer platform can be irradiated in two modes e continuous mode the container with product will continuously move on a conveyer platform in parallel with surface of source rack e shuffle dwell mode the container with product will discontinuously move on a conveyer platform in
20. ed in Fig 26 right upside The sequence of operations to calculate an absorbed dose distribution along any spokes is the following see Fig 26 e Choose and Click on direction of the Spoke along axis X Y or Z Chosen direction will be painted in brown color e For example Selected direction is Spoke along axis Z See Fig 27 For X and Y directions the possible values of coordinates in the XY plane will be appeared The cells number along axis X are in the range from 1 to 40 The cells number along axis Y are in the range from 1 to 50 The cells number along axis Z are in the range from 1 to 100 Maximal number splitting cells along any axis is 100 e Enter the number of cells in the range from 1 to 40 into window X value 1 40 e Enter the number of cells in the range from 1 to 50 into window Y value 1 50 e Click the button Add curve The 6 windows with colour identification and for general characteristics of dose distribution for 6 curves will be opened The general characteristics for the first dose distribution will be located in the first window frame The graph for the first curve for dose distribution will be appeared in the special window see right upside Fig 26 e Another curves for calculated dose distributions along spokes can be located in any of 6 windows Maximal number of curves for simultaneously analysis IS SIX e For this mark by cursor any of 6 windows e Select and Cl
21. f Gamma irradiator will be opened See Fig 5 f Source of Gamma Ray ModeGR 1 2 2009 Radius cobalt slug 2 Height cobalt slugs a Radiue end cap 4 Height end cap 5 Radius of capsule 6 Distance between pencils axes Distance X between modules Number of pemcils 6 Distance Y between modules ee eo ee Module 1 Module 2 Module 3 Module 4 GEE _ Al H Activity i Activity s Activity a 1 o 1 D 1 T 1 o 2 30 z 0 z Zz a 3 4 3 0 a 3 a 4 2 4 0 4 4 a v ___v vt __ ____ v Fill o Fillactivity table table Source E 9 Distance 2 source packages 10 Distance Y source packages a w 11 Left part of irradiation field 12 Right part of irradiation field 100000 1000 Par Continuous mode Conveyor speed Ul 12 o Discrete mode Speed in cmJeec Time in sec other values in cm Save data and close this window Fig 5 The main form of Source of Gamma Ray for entering of input data and correction of Gamma source rack parameters The form comprises three parts e top part contains of characteristics for gamma ray source pencils e middle part contains of characteristics for source modules and source rack e lover part contains of the parameters of mutual arrangement for source rack and container with irradiated product 3 1 Input data of source pencils There are two types of source pencils which are used in the gamma irradiator model e active cobalt
22. ick on direction of the Spoke along axis X Y or Z e Enter the number of cells in plane which will be intercrossed by spoke e Click the button Add curve e You can Delete curve Add curve make Normalization of all curves e You can Save data for any of curves for further analysis e In the left frames of the Results of 3D calculation form you can make DVH analysis in the chosen layer see Fig 26 DVH is characterized by functions pdf and cdf e To make DVH analysis of the functions Probability density function pdf and Cumulative distribution function cdf you can use two Markers located under Left graphs Marker 1 and Marker 2 31 e Click the button Marker 1 enter a cursor in the plot field Locate the vertical red line on the one point of the dose axis by clicking mouse in the chosen point e Click the button Marker 2 enter a cursor in the plot field Locate the vertical red line on the second point of the dose axis by clicking mouse in the chosen point The plot will be separated with markers on three parts along axis Dose e Click the button Calculation The analysis of DVD data results for the three parts will be appeared in the left downside of the form Results of 3D calculation e You can save the analysis of DVH data by use the button Save DVH data
23. iguration is presented in Fig 4 The 64 Aluminum containers with product are moved around the Co source rack on a conveyor 4 passes at two levels Two levels are characterized by horizontal and vertical movements of the product containers Al containers 64 Co 60 Source Rack Conveyer 2nd level Conveyer Ist level Fig 4 Sequence of irradiation in a flat panoramic Co source rack multipass two direction multiposition The 64 aluminum containers with product are moved around the Co source rack on a conveyor 4 passes at two levels A is a fixed point on the side surface of the process load which passes through the irradiation room on both sides of the Co source rack from position 1 to position 64 with two passes on each side of the source In multipass shuffle dwell mode of operation the product containers stay at the designated irradiation positions around the radiation source for a certain dwell time and then they all move to the next positions such that each container irradiated at each dwell position before leaving the irradiation room There are 16 dwell positions for each of the four passes and 64 for the four passes As a result the product irradiated with gamma ray at two sided 3 Input data e Click the File in the main form of the Software ModeGR then Open configuration then select irradiating system and load the file Test rts The frame Source of Gamma Ray with characteristics o
24. ion tasks in radiation processing 7 Built in tools for processing of experimental dosimetric data and their comparison with simulation predictions NWO me The software have intuitively clear graphical interface for the end users with the following features 1 Detailed decomposition of input data for main elements of source and target including spectral characteristics for irradiation source 2 Two levels for entering of input data via configuration files and manually 3 Expert control for the range of input data and co ordination for the set of geometrical and physical input data 4 Compatibility of export an input data to different modules The software ModeGR works on platform Windows98 Me NT XP 2000 Language of the interface English Software ModeGR How to get results u Mode o TX File Options Help About dumber ot i ii i trajectories AI gaa Tara et Simulation 20 41 11 start 19 55 14 finished 20 01 00 Open and view results from tile Comparison Dosimetry fhonte Carlo successtuled Fig 1 The main form of the Software ModeGR ModeGR consists of three thematic modules and service blocks See Fig 1 e Monte Carlo MC simulation module is intended for exact calculations of Gamma ray absorbed dose in irradiated target e Comparison module is intended for scientific analysis and comparison calculated and prepared experimental data for the 2D dose distributions
25. m vault e Parameters simulation Energy cut off and Splitting on axis X Y Z e Parameters of visualization of results Joined cells for center and boundary Coordinate system normal and turn 90 See Fig 18 a b 21 p f Options ModeGR 1 1 20 2 r f Options ModeGR 1 1 20 2 OX r fe Atomatic parameters C Manual parameters f Automatic parameters Nanual parameters Parameters of visualization of results Parameters of visualization of results C i w Coordinate system normal i Coordinate system turn 90 Joined cells for center 2 Joined cells for boundary 1 Joined cells for center 20 Joined cells for boundary 10 Parameters of simulation Parameters of simulation Energy cut off Mev o Splittings on axis 100 Energy cut off hie of Splittings on axis X 20 Splittings on axis Y 100 Splittings an axis 7 30 Splittings on axis 2 100 Splittings on axis Z 100 Expert modes of simulation Seattering from wault Expert modes of simulation W Scattering from vault Hormal f Without scattering i Normal f Without scattering Sa das and sea iaiia Sawe data and close this window Figs 18 a b Main form of Options for entering of input data for MC simulation a default mode Automatic parameters b regime Manual parameters In the default mode Automatic parameters of the Software ModeGR work all simulation parameters
26. nder Gamma ray irradiation e Simulation model of the software ModeGR for target irradiation allows to irradiate the box with flat layers from any of six box sides Selection of target orientation relatively incident Gamma ray is realized with the switch Orientation See Figs 9 and 12 Orientation C Along the scanning axis Normal displacement f Vertical C Along the conveyor axis Turn on 90 deg Fig 12 Frame with mode switch of orientation for target layers under Gamma ray irradiation e Switch positions Vertical and Normal displacement in Fig 12 are used as default mode 16 This target position is mean that all flat target layers are located on conveyer platform in accordance with position in Fig 13 1 I e the planes of all layers are perpendicular to axis of incident Gamma ray beam The length of layers is located in direction of conveyer motion axis X the width in direction of source rack haigh axis Y the thickness in direction of Gamma ray incidence axis Z in parallel with an incident Gamma ray axis Z e All possible positions of layers orientation on a conveyer platform under Gamma ray irradiation and corresponding switch positions are presented in Figs 13 1 13 2 13 3 13 4 13 5 13 6 e Note In any layer positions under Gamma ray irradiation axis coordinates X Y and Z are hard connected with width X length Y and thickness Z of target layers e All above possible po
27. nted in the form e Average dose e Effectiveness e Dose uniformity ratio 28 10 4 Output Data for 3D dose calculation 10 4 1 Dose Volume Histogram DVH analysis e Click the button Show 3D results in the Form with 2D depth dose distribution the form of Results of 3D calculation will be opened for analysis of the DVH and 3D absorbed dose distributions for the 1 layer in the 1 package See Fig 26 This layer was enter as input data in the Target example for simulation See Fig 20 You can made the DVH analysis via the functions pdf and cdf ina such way as it was made in the above part see Fig 25 Results of the DVH analysis for the 1 layer in the 1 package are presented in Fig 26 f Results of 3D calculation ModeGR 1 2 2009 15 20 25 Dose kGy pdf probability density function 1KGy cdf cumulative distribution function Dose 2 43 2 92 DD nannas n nnaArr Package 1 Width X 20 00000 Splitting on X 100 lt mM E Layer 1 Length 20 00000 Splitting on 100 a rol Thickness Z 10 00000 Splitting onz 100 DUR 11 085790 Average dose 6 993684 Marker1 Maker Calculation of integrals salati Along Z Along Y Along X 2 7031 10 421 Save normalized data X 50 X 50 Y 50 Y 50 Z 50 Z 50 1 0 00020100001 2 0 891481 3 0 108318 From 2 4307077 From 2 9210201 From 10 275706 Dmin 4 09547 Dmin 4 93805 Dmin 3 93672 To 2 9210201 To 10 275706 To
28. of an irradiation process are calculated with use of a Monte Carlo method The software ModeGR provides the end user with data sets in the graphic and tabular form the 2D and 3D absorbed dose distribution within the product irradiated with a gamma rays from flat panoramic Co source rack The ModeGR contains a set of tool means for the comparative analysis of the obtained data for absorbed dose of gamma ray Service blocks of the program in reporting forms give the user the necessary and sufficient information for decision making at e the choice of optimum conditions the configuration parameters and operating modes of the radiation facility e the configuration of the irradiated objects with taking into consideration of features irradiated materials e the organizations of a dosimetric control during materials processing e the confirmation of a correctness verification of results of the carried out irradiation The features of the software ModeGR are as follows Two levels for entering of input data via configuration files and manually Built in tools for statistical analysis 3 Built in tools for uncertainties estimation of results simulation due to uncertainties of input data for radiation facility 4 Estimation of uncertainties for physical models 5 Built in tools for dose volume histogram analysis 6 Comparison Modulus for visual and a numerical analysis of calculated and experimental data and for decision of optimizat
29. orner in the Target frame See Fig 9 e Enter for each layer Thickness in cm e Enter for each layer Width in cm Note The Width of packages can be gt Width of each layer e Enter for each layer Density of materials in g cm 15 e Select a material for each layer from the Table of material The atomic number Z and the atomic weight W of the material appear in the corresponding boxes e For materials not given in the Table of material enter the values of Z and W The selection button changes to Another material e Button Delete is used for deletion of the selected layer e Button Clear is used for cleaning of the parameters in the selected layer 4 4 Input data for cover size and_ cover materials e Enter characteristics for the Cover Box Cover thickness in cm Additional cover thickness in cm and Density of cover materials in g cm Note In the case of cover thicknes 0 the multilayer target has not a Cover Box e Select a material for cover materials from the Table of material The atomic number Z and the atomic weight W of the material appear in the corresponding boxes e Enter the values of Z and W for materials not given The selection button changes to Another material e Multilayer target can be irradiated by incident Gamma ray either in closed or open Tick window Opened cover Cover Box See Fig 9 5 Input data for layers orientation on a conveyer platform u
30. ose 0002235 key a 0 0022 1 wj Layer width cem 20 0 00 24 8474 0 002173 0 002 eq ew 20 0 00 196 25670 MELER 7 0022 0 002144 0 002 Step onlengthitem 1 0 00 29453500 0 002144 0 002 0 00 483 61920 A Average dose key 000178 0 002128 ood i 0o00 501 80040 Calculation nin Thad 0 002122 0 0021 eee ssi 0 00 54179900 DUR 2 440654 gt Dose Uniformity Ratio 2 165 0 00 603 61490 E Aor Fig 24 Left Graph 3D view of the depth dose distributions of Gamma ray Dose Map along layer length axis Y and along layer width axis X in graphical and tubular forms for the 1 layer in 1 package The dose value is integrated along layer thickness axis Z Right graphs Cumulative distribution function cdf violet curve and Probability density function in 1 kGy pdf green curve e To make Dose Volume Histogram DVH analysis via the functions the Probability density function pdf and the Cumulative distribution 21 function cdf you should use two Markers located under Right graphs Marker 1 and Marker 2 e Click the button Marker 1 enter a cursor in the plot field Locate the vertical red line on the one point of the dose axis by clicking mouse in the chosen point e Click the button Marker 2 enter a cursor in the plot field Locate the vertical red line on the second point of the dose axis by clicking mouse in the chosen point The plot will be separated with markers on
31. parallel with surface of source rack to a new irradiation position and then remaining at rest for a dwell time at that position Where the dwell time is the time interval during which a process load is at rest at an irradiation position Notes e Multi layer target can be located on the conveyer platform with without packing box e Front face of packing box can be open for all above targets Multi layer target consists of identical packages with flat sheets of materials with various density and atomic number e The number of packages are in the range from 1 to 10 e The number of layers flat sheets of materials with various density and atomic number in the each package are in the range from 1 to 6 e The number of layers in Multi layer target are in the range from 1 to 60 All packages have the same set of materials and identical geometrical sizes LY f Travel D distance between boxes Fig 3 2 Geometrical model of 3 identical Multi layer targets with packing box on a conveyer platform irradiated with Gamma ray The distance D between boxes with Multi layer targets can be gt 0 Conveyer 2 Co multipass shuffle dwell irradiator The computer model allows calculate the absorbed dose distribution and optimize dose uniformity within product irradiated on Co multipass shuffle dwell irradiator The schematic model of a typical Co multipass shuffle dwell irradiator with overlapping product to gamma source conf
32. placed in closed packing box with additional packing materials b Multi layer target consists of 6 layer package placed in closed packing box with additional packing materials b multi layer targets irradiated with Gamma ray in parallel with interface of contacting materials 14 Simulation of the dose distribution in the Several identical Multi layer targets with without packing box allows to investigate the mutual influence of the nearest neighbor boxes on dose field formation in the target layers e The flat sheets of Multi layer target can be located on the conveyer platform horizontal or vertical relatively incident Gamma ray axis See Figs 10 and 11 Note In any layer positions under Gamma ray irradiation axis coordinates X Y and Z are hard connected with width Y length X and thickness Z of target layers See Figs 10 and 11 D Conveyer Travel D distance between boxes Fig 11 Geometrical model of 3 identical Multi layer targets with packing box on a conveyer platform irradiated with Gamma ray The distance between boxes with Multi layer targets can be 0 4 3 Input data for layers size and layers materials e Enter the number of packages in multi layer target in the range from 1 to 10 e Enter the number of layers in the package in the range from 1 to 6 For this Click the button Insert right up corner in the Target frame See Fig 9 e Enter the Width of packages in cm left up c
33. r volume is splitted by 3D grid with bin cell size AV AX AY eAZ Where AX Width N x AY Length N y AZ Thickness N z N x N y N z the number of splitting along the Layer Width axis X Length axis Y and Thickness axis Z respectively e the spokes can intercross the layer in any point of its surface in directions of axis X axis Y and axis Z perpendicularly to planes of a layer e the absorbed dose distribution is calculated in the spokes volume in directions of axis X axis Y and axis Z the spoke volume size in directions of axis X V X WidtheAY AZ the spoke volume in directions of axis Y V Y LengtheAX eAZ the spoke volume in directions of axis Z V Z ThicknesssAXeAY e at calculation the dose distribution along spokes the absorbed dose averaging in each splitting point along spoke is realized in volume AV AX AYeAZ Example of target layer with grid and spokes is presented in Fig 27 Layer is located on a conveyer platform Spoke A intercross a layer thickness along axis Z Spoke B intercross a layer length along axis Y Spoke C intercross a layer width along axis X e ig tt wit tT Fig 27 Target layer with grid and spokes located on a conveyer platform 30 For above example see Figs 20 and 26 all geometrical characteristics Thickness Width and Length and splitting along axis X axis Y and axis Z for the 1 layer in 2nd package are present
34. rce Modules Fig 8 The model of flat panoramic source rack comprises of four above source modules in 2 x 2 array e Enter the values into windows Distance X between modules and Distance Y between modules in cm Distance X and Distance Y characterize the displacement between modules along axis X and axis Y See Fig 8 e Enter the Number of pencils the number of source pencils in each source modules See Fig 5 middle part The tables Modulel Module 2 Module 3 and Module 4 will be opened Each of tables have the rows number equal to the Number of pencils These tables are used for entering of Cobalt 60 Activity in Ci for each source pencil in corresponding modules e Enter the values of Activity in Ci to each source pencil in the tables Modulel Module 2 Module 3 and Module 4 e Enter 0 in rows of Modules where the pencils with cobalt slugs and blank pencils are absent e Enter 1 in rows of Modules where the blank pencils are located In this way you can Enter the values of Activity in Ci to source pencils step by step in all source modules 11 There are service for accelerating of entering of the value of source pencil activity in the tables of Modules for cases e when source module contains a big number the blank pencils or e when source module contains a big number the absent pencils For use service e
35. results from file in the Main form of the Software ModeGR Fig 19 e The button Prepare store results to compare is used to select the 2D depth dose distributions for certain layer and package from simulation results previously stored in the files and to prepare their for use in the module Comparison Note The button Prepare store results to compare is active only after operation in the privies point 26 e To copy the graphical depth dose results into your document Click graph either of the Center or Boundary Click the button To clipboard and paste them to your document e The button Prepare data to calculate SAL is used for preparation of the dose map data in the chosen layer Further the dose map data can be used as input data in the software ModeSAL for calculation a sterility assurance level SAL e The software ModeSAL and ModeGkR are the simulation modulus of the RT Office information system Input and output data for all simulation modulus of the RTOffice are self consistent between themselves 10 3 Output Data for 3D view of an absorbed dose distributions e Click the button Analysis of the dose the form Dose map for corresponding layer and package will be opened see Fig 24 t Dose map for package 1 layer 1 ModeGR 1 1 2008 ph r Dose ky pdf probability density function 1KGy 3 cdf i cumulative distribution function 3 Probability Marker 0 0018 Scaling D
36. sitions under Gamma ray irradiation also can be realized for package of flat layers placed in open closed box See Figs 14 1 and 14 2 and for package of flat layers placed in open closed box with additional cover See Figs 15 1 and 15 2 Additional cover always covers only the box sides in direction of layers thickness along axis Z Switch position 1 Switch position 2 Vertical Normal displacement Vertical Turn on 90 degree WW WA Conveyer Scan Conveyer Scan platform platform lt Length Y Target Travel Travel Fig 13 2 Switch position 3 Along the conveyer axis Normal displacement LUIL a Length Conveyer Scan platform Target E b fe ae Fig 13 3 Switch position 5 Along the scan axis Normal displacement o HUUUHY 7 X Conveyer Scan platform Target T b a ran m Fig 13 5 17 Switch position 4 Along the conveyer axis Turn on 90 degree Hehh Y Width Conveyer Scan platform Target E b oS ae Fig 13 4 Switch position 6 Along the scan axis Turn on 90 degree PLL Y a ty Z oD Y Conveyer Scan platform Target E b oS ae Fig 13 6 Figs 13 1 13 2 13 3 13 4 13 5 13 6 Layers orientation on a conveyer platform under Gamma ray positions irradiation and corresponding switch 18 Switch position 1 Switch position 2
37. ulti layer target consists of some identical packages with flat sheets of materials with various density and atomic number e The number of packages are in the range from 1 to 10 e The number of layers flat sheets of materials with various density and atomic number in the each package are in the range from 1 to 6 See Figs 10 a b c e The full number of layers in Multi layer target are in the range from 1 to 60 e All packages have the same set of materials and identical geometrical sizes e All flat sheets of 6 layers in the package can have different thickness axis Z and width axis Y along source rack heigh but all sheets have identical length axis X along conveyer motion e Multi layer target can be located on the conveyer platform with without packing box e Several identical Multi layer targets with without packing box can be located on the conveyer platform See Fig 11 The distance between boxes with Multi layer targets can be 0cm Geometrical models of multi layer targets irradiated with Gamma ray 1st 2nd additional package package packing b Multilayer closed target packing box Multilayer Multilayer target target closed packing box closed packing box H a Ta a H Conveyer X Y Figs 10 a b c Geometrical models of multi layer targets on moving conveyer irradiated with Gamma ray Conveyer moves along axis X a Multi layer target consists of two 6 layer packages
38. ution The cells are combined in direction transversely to axis of Gamma ray dose distribution visualization 2 Coordinate system normal and turn 90 Under visualization of results regime turn 90 rotate the Coordinate system for the irradiated target on 90 degree around axis Z in comparison with regime normal Regime turn 90 is working only under visualization of 2D absorbed dose distribution Under visualization of simulation results in regime Coordinate system normal the 2D absorbed dose distribution is presented along layer width Under visualization of simulation results in regime Coordinate system turn 90 the 2D absorbed dose distribution is presented along layer length 9 3 Parameters simulation Energy cut off and Splitting on axis X Y Z e Change of simulation parameters Energy cut off can be used for scientific researches of transport irradiation through heterogeneous targets Note In all above Expert modes of simulation Normal Without scattering parameter simulation such as Energy cut off is automatic installed e Parameters simulation Splitting on axis X Y Z are used for the selection of optimal value of 3D grid for target layer at analysis of 3D absorbed dose distribution in this layer All parameters of Options can be changed only in regime Manual parameters 10 The features of output data presentation 10 1

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