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        WHEATON Roller Apparatus
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1.    deck spacing for easy removal and  replacement of bottles  These are kits designed for customer installation     The deck kit is designed for production systems with removable decks   Production systems have 6    deck spacing to maximize system capacity   These are kits designed for customer installation        Cat  No  Description                      02 924 964 WHEATON Standard Roller Top Drive System Options with Belt Break  Alarm and Battery Backup  02 924 966 WHEATON Standard Roller Bottom Drive System Options with Belt  Break Alarm and Battery Backup  02 924 965 R2P 2 0 Roller Top Drive System Options with Battery Backup and  Temperature Sensors  Belt Break Alarm is already included with unit   02 924 967 R2P 2 0 Roller Bottom Drive System Options with Battery Backup and  Temperature Sensors  Belt Break Alarm is already included with unit   02 912 629 Deck Installation Kit for Modular  7 125     Spaced System   Units have a maximum capacity of 9 decks   02 912 630 Deck Installation Kit for Production  6     Spaced System   Units have a maximum capacity of 11 decks   For customer service  call 1 800 766 7000   To fax an order  use 1 800 926 1166  w    To order online  www fishersci com    UniSpense    OmniSpense   and WHEATON   are registered trademarks of WHEATON    Industries Inc  R2P    is a trademark of WHEATON Industries Inc  Microsoft     Windows   and Vista    are either registered trademarks or trademarks of Microsoft  Corporation in the United States and or o
2.  But while I sit here as a Product  Manager looking at double digit year over year growth for the equipment  once considered  the bane of bio production    would have been very wrong  New innovations such as surface  treated plastics and automated harvesting systems have helped maintain the requirement for  the roller apparatus line  The ease of implementation  scaling  difficulties with suspension cell  culture and increased industry titers have helped the growth of the line  And for the future   drug delivery methods  advances in adjuvants  and the pursuit for rare disease therapies will  ensure that production line of the equipment will keep on rolling  To make sure that the best  possible equipment is implemented in the field we are investing heavily in the line  Service free    motors  gold plated surface mount electronics  ruggedized communications and networking  protocols  and an icon driven touch screen interface are just a few of the enhancements           m Records all settings  changes  alarms and communication loss       The WHEATON CART2 System precisely controls rotating speeds of  up to 255 separate roller units  Each unit is monitored for rotation   speed deviation and communication  This system provides the       EP  El           WHEATON       R2P  2 0 Roller Apparatus  for Adherent Cell Culture                        Available in Top or  Bottom Mounted  Countrol    m  Robust touch screen interface that is easy to view from a distance   m Readily recognized 
3. 0 240 VAC  50 60 Hz  35W       Complimentary WHEATON    Products    Peristaltic Pumps    Silicone Tubing    Incubators    Vented Caps    Roller Bottles e Bench Top Rollers    Peristaltic Pumps Incubators Vented Caps  Standard  amp  CO                    UniSpense   PRO OmniSpense   ELITE       Silicone Tubing    Micro Cassette Platinum Cured Peroxide Cured    g     PD a  M he le g    y   I a        dD    Bench Top Roller        The First Single Use Bioreactor  Monitoring Software    CART2 Control Monitor and    Recording Software         Remotely monitors and controls up to 255 R2P and R2P 2 0 rollers      Password protected user levels maintain security  m Can be easily added to R2P and R2P 2 0 at any time    Conforms to UL  CSA and CE Laboratory Standards    CART  Screen perfect solution for GMP or FDA requirements     CART2 and View Log Software    with the Network Interface  Network Interface is a single line network adapter for up to 255 R2P units  Computer Requirements    Cat  No  Plug Style  02 912 635 North America    Voltage Qty Case  120 VAC 1    m IBM Pentium   PC or compatible          Brian Canna   Global Product Manager  Bioprocess Equipment  B S  Biochem  MBA    m 32 MB of RAM  minimum   m Microsoft   Windows   2000  XP  Vista  7  m One free serial port   m  10 MB of free hard drive space  minimum       Five years ago as a bioreactor sales engineer if you asked me about the future of roller culture     would have said it was going to go the way of the dinosaur 
4. 2 5 9 30 76 25 63 71 179 238 108 45 R2P 2 0  02 924 918 5 9 30 76 25 63 71 179 238 108 45 Standard  Top Drive Production Spacing   02 924 904 5 11 31 79 25 63 75 190 250 113 52 R2P 2 0  02 924 900 5 11 31 79 25 63 75 190 250 113 52 Standard  02 924 906 8 11 47 120 25 63 75 190 350 159 85 R2P 2 0  02 924 902 8 11 47 120 25 63 75 190 350 159 85 Standard             The First Single Use Bioreactor  WHEATON    Standard Roller Apparatus    Product Specifications  Standard Roller       mw Smooth ramping digitally controlled rotation accurate to 0 1 RPM  m  Maintenance free precision brushless motor  Bright digital display for easy operation    Multiple decking and capacity configurations available for process flexibility                Specifications  NOE AAO E A E E 5 88 Positions  Bottle Speed  110mm Diameter Bottle  other speeds available         0 25 8 1 RPM  Pote DAMCI ancii uis esn E E E 108 121mm  Bottle Length  csscescieasaacenee iat thtlideeneteeccuneiticnsinenrteadeenttiaec iis Up to 550mm  PG AIA Ys me E uated hacen cosh Abesecstnendedad nce 0 1 RPM  Ve PEE E tess EEEN E E I E EE E sions ae Belt Driven  LOC a OG  E E E E A OER Brushless DC  ROTATION DINGCTIONS oriai Clockwise and Counter Clockwise  Qpt  ONSi  nn Belt Break Alarm and Battery Backup  Remote COMMUN  CAt  ON   cns Dry Contact Relay Alarm  wian a ie A E E EEEE E E E E E E 80  up to 31  C  Operating Temperature           scccsssecssssccssssscrsssssssscrsvessrssssssessresersses 10 to 40  C        ee en ee ee 10
5. E  Fisher Scientific WHEATON    Roller Apparatus  R2P    2 0 and the WHEATON Standard Roller  for Adherent Cell Culture    The First Single Use Bioreactor    www wheaton com          WHEATON       Roller Apparatus    R2P     2 0 and the WHEATON Standard Roller        TUUT   FIA   ak  jiii  r  acs                         for Adherent Cell Culture    The First Single Use Bioreactor    We have updated and enhanced our process control  systems for our production scale roller apparatus  We  understand the importance of our culture systems to  the vaccine and biologics industries  therefore  customer  input was a key driver governing the upgrades  The systems  utilize current technology to facilitate implementation  into new production installations with networked  equipment  The systems also maintain backwards  compatibility for existing operations  This effort will  also enable better control and monitoring for research  or pilot roller culture installations     The new roller apparatus feature       A color touch screen or digital display  s An icon driven interface with intuitive menus    m The surface mount gold plated electrical connections  for better reliability in high temperature environments    m Updated industry standard networking commun   ications protocols and connections    m Lower power consumption for longer battery run  time and a safer design    a   Backwards compatibility for continuing support of  existing installations    a Retrofit kits available to update o
6. icons for intuitive navigation   m Digitally controlled maintenance free motor accurate to 0 01 RPM   m Capable of remote control and monitoring through SCADA systems     Multiple decking and capacity configurations available for process flexibility      USB Downloadable System Event Log    Specifications  CCI AG E asad E E E E E A EE E 5 88 Positions  Bottle Speed  110mm Diameter Bottle  other speeds available        0 25 8 1 RPM  PC WA ee ccsecire te ecete bance A 0 01 RPM  DAVE aaen petted E cas eae anrancceenbafotscanaanaticens Belt Driven  Motor TYPE iarrann anann aa aaa AANER ten Brushless DC  Rotation Direction      ecn Clockwise  Counter Clockwise and Rocking  Belt Break Alah mesrinpnrnienei a e e ERE Included                    Modbus   Protocol and WHEATON Protocol via Ethernet TCP IP and RS422 485  O aa N 80  up to 31  C  Operam TEMP aE soies ee E uoyenoncantess 10 to 40  C  INETI OERE AEAEE E T 100 240 VAC  50 60 Hz  35W         01 10 0 10  01 00 00    Say Goodbye to Quick Start Cards and  User Manuals      m e e e e e e e e e m    The R2P 2 0 touch screen was designed for use directly  out of the box  There are four types of screens for system  navigation  The Main Screen displays all of the most  important process conditions including bottle speed  bottle  direction  alarms  unit identification number  power status   and the network status  From the main screen the user can  access the general Setup Screen     Profile    The user can configure system parameters 
7. lder WHEATON  systems or unsupported systems      Maintenance free brushless DC motors for years of  trouble free operation    WHEATON has a long history of designing  building  and supporting cultivation equipment  The R2P 2 0  and the WHEATON Standard Roller are the next logical  steps     P 2 0       WHEATON    R2P  2 0 Roller Apparatus  and the Standard Roller    Select the  Control System    Configure the  Decks    Determine the  Capacity    Select the  Options                Low Consumable  Cost    Easily Scalable    Process Automation    Capabilities    Low Capital  Investment    Easy to Operate    Reduced Cleaning  Validation    Reduction of  Loss Potential               Width    Decks    Dia    in   cm        Part Number   Positions    Weight   in   cm       of Bottle   ea     Positions                Control  System                                                    Bottom Drive Production Spacing   02 924 936 5 1 31 79 25 63 14 35 52   24 5 R2P 2 0  02 924 938 5 3 31 79 25 63 26 65 85   39 15 R2P 2 0  02 924 948 5 11 31 79 25 603 74 187 217 99 55 R2P 2 0  02 924 950 8 11 47 120 20   63 74 187 360 167 88 R2P 2 0  Bottom Drive Modular Spacing   02 924 952 5 1 30 76 25 63 14  34 70 32 5 R2P 2 0  02 924 908 5 1 30 76 25 63 14  34 70 32 5 Standard  02 924 954 5 3 30 76 25 63 29 74 112 51 15 R2P 2 0  02 924 910 5 3 30 76 25 63 29 74 112 51 15 Standard  02 924 958 5 6 30 76 25 63 48   122 205 93 30 R2P 2 0  02 924 914 5 6 30 76 25 63 48   122 205 93 30 Standard  02 924 96
8. that are frequently  accessed from the Setup Screen including speed ramp  time and the event log  All parameters are changed in  Configuration Screens that feature large numeric keypads  and intuitive operation  The Setup Screen also allows  access to the Factory Screen for system parameters that are  established during factory assembly and testing  All screens  can access an onboard user guide that details the function of  each Icon  Don   t worry we will still include the user manual   you may just never need it     WHEATON R 2P 2 0       Main Screen          WHEATON R2P 2 0 WHEATON R2P 2 0       Bottle Speed Factory Setup    The First Single Use Bioreactor  Roller Options Information    Belt Break peal ae sl R2P 2 0     The Belt Break 0   sensors to ensure that  all main pulleys a are Pae on the unit  This is included on all R2P  2 0 Roller Apparatus     sala gead   The B te    in asport  processing and  power    outages  The unit e sit ae switches  over to battery power to provide rotation for 12     24 hours  Bottom  mounted control systems house larger  longer lasting batteries     Temperature Monitoring Alarm Option   R2P 2 0 Sa    This option   p   for real  time temperature monitoring an ra alarms  The temperature  is displayed in the temperature calibration screen or on the screen  saver for quick confirmation of optimal operating conditions     E  Fisher Scientific       The deck kit is designed for modular systems with removable decks   Modular systems have 7 125 
9. ther countries  Pentium   is a trademark  of Intel Corporation in the U S  and or other countries  Modbus   Protocol is a  registered trademark of Schneider Electric S A  or its subsidiaries in the U S  and     or certain other countries     Copyright    2012 WHEATON Industries Inc  Printed in USA     FBRO_006 05 2013                   
    
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