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QAII C Station Operator`s Manual

1. Variable Default Values RPM 000 00 Wobble 00 00 Temp 1 5 Shaft X 6 8 Shaft Y 6 8 Table X 6 8 Table Y 6 8 Vibration X 0 000 Vibration Y 0 000 Vibration Z 0 000 Frequency 000 00 Velocity 00 00 Displacement 0000 Varian Inc Chapter 6 Service and Warranty The warranty is provided by Varian Inc or one of its authorized representatives Service and Warranty Information Varian Dissolution products carry a one year warranty on parts and labor The Dissolution Systems Service Department or one of its representatives will at its option either repair or replace any mechanical and electrical components in your instrument which prove to be defective During the first year of warranty coverage there is no charge for the labor to repair your unit The Dissolution Systems Service Department or one of its representatives will determine the best site to repair the unit either onsite or returned to Varian Inc Any onsite warranty services are provided only at the initial installation point Installation and onsite warranty services are available only in Dissolution Systems service travel areas Varian Inc Page 78 QAII C Station Revision E 11 10 Service and Warranty Operator s Manual P N 70 9040 Exclusions and Limitations Excluded from this warranty are expendable or consumable items such as but not limited to paddles baskets vessels and acrylic water baths Also e
2. Varian Inc Revision E 11 10 QAII C Station Page 31 P N 70 9040 Operator s Manual Operation Operating the QAII C Station Step 1 Ensure the power switch is in the OFF position Step 2 Ensure all accessories are connected to the QAII C Station rear panel See Setting up the QAII C on page 25 Step 3 Turn on the QAII C Station The following screen displays for three seconds VARIAN INC QA II C TEST STATION PROGRAM REV 4 20 09 30 2004 15 37 37 Step 4 The monitor screen displays see page 26 Step 5 Press MENU to display the QA II C Main Menu screen QA II C MAIN MENU 1 SETUP 2 VIBRATION 3 SET CLOCK 09 30 2004 15 37 37 Following is a description of the QA II C Main Menu screen options Option Response 1 Setup See Main Menu Option 1 Setup on page 32 2 Vibration See Main Menu Option 2 Vibration on page 36 Varian Inc Page 32 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Option Response 3 Set Clock The QA C Main Menu screen displays the date and time of day in 24 hour format For example 14 55 indicates 2 55 pm 09 05 indicates 9 05 am To change or correct the date or time of day select option 3 Set Clock The date displays Press ENTER to accept the current date or enter the new date and press ENTER The time displays Press ENTER to accept the current time of day or enter the cor
3. or Press ENTER e Key sequences you are asked to press appear like this MENU gt 2 Note Remember to return the warranty card supplied with this manual Completing and returning the card ensures your right to QE protection under the terms and conditions of your warranty It also enables us to better assist you in the event of any problems Additionally it guarantees you will be informed of any issues that arise concerning your equipment such as upgrades retrofits or regulatory changes Varian Inc Page 18 QAII C Station Revision E 11 10 Introduction Operator s Manual P N 70 9040 This page was intentionally left blank except for this message Varian Inc chapter3 Installation and Setup Unpacking Your QAII C Station Follow these steps to safely unpack your QAII C Station Step 1 Open each carton and check the contents for damage which may have occurred during shipping Shipping damage rarely occurs but if it does contact both the carrier who delivered the instruments and the Dissolution Systems Service Department Though claims for damage should be filed with the carrier we can help you file a claim Step 2 Carefully remove the QAII C Station base unit digital wobble gauge and magnetic tachometer sensor attached to an EaseAlign mounting bracket and universal adapter magnetic clip electronic level sensor precision temperature probe electronic vibration sensor
4. NOTICE This document contains references to Varian Please note that Varian Inc is now part of Agilent Technologies For more information go to www agilent com chem ee Agilent Technologies QAII C Station Operator s Manual P N 70 9040 November 2010 Revision E Limitation of Liability The information in this document is subject to change without notice Varian Inc makes no warranty of any kind with regard to this material including but not limited to the implied warranties or merchantability and fitness for a particular purpose Varian Inc shall not be liable for errors contained herein or for incidental consequential damages in connection with the furnishing performance or use of this material All rights are reserved Reproduction adaptation or translation without prior written permission is prohibited except as allowed under copyright laws First Edition November 2010 QAII C Station Operator s Manual Part Number 70 9040 Revision E Printed in the United States of America The following terms are trademarks of Varian Inc Benchsaver e Practical Solutions BIO DIS III QA and QAII e Enhancer Cell e TruCenter Full Flow Filters VanKel e Peak Vessel e VKE All other trademarks are the property of their respective owners Varian Inc 13000 Weston Parkway Cary North Carolina 27513 2250 800 229 1108 919 677 1108 Fax 919 677 1138 www varianinc co
5. P N 70 9040 Magnetic Tachometer Sensor The magnetic tachometer sensor is also mounted on the EaseAlign mounting bracket The sensor detects the rotations per minute of the paddle or basket shaft with the use of a magnetic clip FIGURE 3 Magnetic Tachometer Sensor tachometer sensor EaseAlign mounting bracket Magnetic Clip The magnetic clip is used in conjunction with the magnetic tachometer sensor Each time the magnet passes the sensor one rotation is counted FIGURE 4 Magnetic Clip Varian Inc QAII C Station Revision E 11 10 Page 22 Operator s Manual P N 70 9040 Installation and Setup Universal Adapter The supplied universal adapter allows the QAII C Station to be used in conjunction with any Varian dissolution apparatus including older models or with any non Varian dissolution apparatus The adapter provides locating pegs to secure the EaseAlign mounting bracket with wobble gauge and tachometer sensor to the dissolution apparatus vessel FIGURE 5 Universal Adapter locating peg EaseAlig mounting bracket universal adapter Electronic Level Sensor The electronic level sensor allows you to check the level of the vessel plate and drive unit as well as the perpendicularity of each shaft from side to side and front to back simultaneously The sensor has a range of 9 9 to 9 9 degrees FIGURE 6 Electronic Level Sensor Varian Inc Page 23 Revision E
6. 11 10 QAII C Station Installation and Setup P N 70 9040 Operator s Manual Electronic Vibration Sensor The vibration sensor can be placed either on the vessel table or on the drive unit in the upright position to obtain readings The sensor can be used to measure vibration on the X Y and Z axes individually FIGURE 7 Electronic Vibration Sensor Temperature Probe The temperature probe allows you to measure the temperature of the medium in the vessel The temperature probe can also be used to measure the temperature of the water in the water bath or any other aqueous based solutions FIGURE 8 Temperature Probe Warning The QAII C Station contains electrical circuits devices and components operating at dangerous voltages Contact with these circuits devices and components can cause death serious injury or painful electric shock Varian Inc Page 24 QAII C Station Revision E 11 10 Installation and Setup Operator s Manual P N 70 9040 Power Switch Functions Warning Ensure the AC power setting is at the correct voltage for your power supply The power setting is displayed on the back of the instrument on the line fuse holder located next to the power switch To change the voltage see Fuse Replacement on page 73 The electrical connection at the back of the instrument is the primary disconnect FIGURE 9 Line Fuse Holder and Main Power Switch The QAII C
7. XX X C lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Step 3 Press CLEAR to remeasure the vessel temperature Repeat step 2 Optionally press ENTER to continue The following screen displays SHAFT ID _ FOR POSITION 09 30 2003 15 37 37 Step 4 Repeat this entire procedure from step 3 under Entering Physical Parameters Paddles on page 48 for each vessel position Step 5 After the last value prints the following screen displays VESSEL TABLE LEVEL LV X xx x LV Y xx x lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 6 Continue to Measuring Vessel Plate Table Level on page 57 Varian Inc Revision E 11 10 QAII C Station Page 57 P N 70 9040 Operator s Manual Operation Measuring Vessel Plate Table Level Complete the following steps to record the vessel table level Step 1 Place the level sensor in the upright position on the vessel plate The sensor measures in degrees the level from side to side and front to back simultaneously Step 2 Press CLEAR to skip this reading or press PRINT to print the vessel table level The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays VESSEL TABLE LEVEL LV X xx x LV Y xx x lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Step 3 Press CLEAR to remeasure the vessel table level Repeat step 2 Optionally press ENTER to continue
8. provided by the equipment may be impaired The QAII C Station is operated in conjunction with equipment that uses aqueous liquids Unskilled improper or careless use of this instrument can create shock hazards fire hazards or other hazards which can cause death serious injury to personnel or severe damage to equipment and property Information on safety practices is provided with your instrument and operation manuals Before using your instrument or accessories you must thoroughly read these safety practices Observe all relevant safety practices at all times Varian Inc Page 10 QAII C Station Revision E 11 10 Safety Practices and Hazards Operator s Manual P N 70 9040 Electrical Hazards The QAII C Station contains electrical circuits devices and components operating at dangerous voltages Contact with these circuits devices and components can cause death serious injury or painful electric shock Panels or covers that are retained by fasteners which require the use of a tool for removal may be opened only by Varian trained Varian qualified or Varian authorized service engineers Consult the manuals or product labels supplied with the QAII C Station to determine which parts are operator accessible Application of the wrong supply voltage connection of the instrument to an incorrectly wired supply outlet or lack of proper electrical grounding can create a fire hazard or a potentially serious shock hazard and c
9. 3 Step 4 Press and hold the printer toggle switch in the OnLine Off Line position while turning on the instrument Hold the printer toggle switch in the OnLine Off Line position for six seconds after the instrument is turned on then release the switch The printer should print SETUP MENU and CONFIGURE NEXT OK If this message does not print repeat steps 1 through 3 The printer toggle switch is used to complete the configuration Pressing the left side of the printer toggle switch selects NEXT to advance to the next menu item Pressing the right side of the printer toggle switch selects OK to accept what is stated on this line of the menu item Each time the switch is pressed another part of the menu prints Allow the printer to finish printing before pressing the switch again See the table of commands below Note The printout is easier to read if the printer cover is removed SETUP MENU CONFIGURE NEXT OK Press NEXT to avoid configuration CUSTOM NEXT OK Press OK to enter custom mode CUSTOM MENU PRINT CUSTOM SETUP NEXT OK Press NEXT AUTO SEQ NO NEXT OK Press OK ZERO NEXT OK Press OK POUND SIGN NEXT OK Press OK _ UNDERSCORE NEXT OK Press OK ONLINE OFFLINE YES NEXT OK Press OK EXT CH SET NO NEXT OK Press OK PRINT READY YES NEXT OK Press NEXT PRINT READY NO NEXT OK Press OK READY Your printe
10. Baud Rate screen displays SET BAUD RATE 1 1200 2 2400 3 4800 4 9600 09 30 2004 15 35 30 Select the appropriate baud rate If you are running the supplied spreadsheet application the baud rate must be set to 9600 The Comm Config screen displays Press MENU twice to return to the QA II C Main Menu screen Varian Inc Page 36 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Main Menu Option 2 Vibration The QAII C monitor screen displays the g value only To display all other values associated with the vibration reading select option 2 Vibration from the QA II C Main Menu screen Ensure the vibration sensor is in place prior to selecting this option See Figure 18 Vibration Sensor on page 58 Select option 2 Vibration from the QA II C Main Menu screen The Vibration Analysis screen displays VIBRATION ANALYSIS g 0 000 FRQ 000 00Hz VELOCITY xx xx mm S DISPLACEMNT 0 000MIL lt PRINT gt TO PRINT g represents acceleration expressed in mm sec or in sec FRQ represents frequency expressed in Hz Velocity is expressed in mm sec or in sec Displacement is expressed in mm or mils Press PRINT to print the current values Press MENU to return to the QA II C Main Menu screen Opening the Spreadsheet optional To use the spreadsheet in conjunction with the QAII C complete the following steps to open the spreadsheet on
11. Era am Press CLEAR to skip the paddle shaft wobble for this vessel position or press PRINT to print the paddle shaft wobble The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays PADDLE SHAFT WOBBLE POSITION xx xx mm lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Varian Inc Page 54 Operation QAII C Station Revision E 11 10 Operator s Manual P N 70 9040 Step 7 Step 8 Press CLEAR to remeasure the paddle shaft wobble Repeat step 6 Optionally press ENTER to continue The following screen displays PADDLE SHAFT PERPEND POS X xx x Y XX X lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Continue to Measuring Shaft Verticality Paddle below Measuring Shaft Verticality Paddle This accessory is used in conjunction with a centering tool to verify proper shaft alignment Complete the following steps to record the shaft verticality Step 1 Step 2 Stop the spindles Hold the level sensor flush against the shaft The perpendicular groove of the sensor should be placed high up on the shaft approximately 1 inch or 25 4 mm below the bottom of the dissolution apparatus drive unit This sensor measures in degrees the verticality or perpendicularity of the shaft from side to side and front to back simultaneously See Figure 17 Electronic Level Sensor Placement belo
12. X LV Y xx x mm dd yyyy hh mm ss Varian Inc Revision E 11 10 QAII C Station Page 27 P N 70 9040 Operator s Manual Installation and Setup Spreadsheet Installation Note IER For the spreadsheet to install and operate correctly it is necessary to have Microsoft Office 2000 or greater installed as the operating system on the target PC To install the QAII C spreadsheet complete the following steps Step 1 Insert the CD ROM into the CD drive typically D Step 2 If the D screen displays double click setup exe The welcome screen displays If the D screen does not display click Start on the Windows task bar and select Run Click Browse go to the correct directory on the CD based on your operating system select setup exe and click Open Ensure the proper path displays in the Open line of the Run screen and click OK The welcome screen displays Step 3 Click OK to close the welcome screen Step 4 By default the spreadsheet loads into the following directory C Program Files Varian QAIIC Step 5 Follow the remaining on screen instructions to complete the installation Step 6 Click OK when the installation is complete Varian Inc Page 28 QAII C Station Revision E 11 10 Installation and Setup Operator s Manual P N 70 9040 This page was intentionally left blank except for this message Varian Inc chapter4 Operation The QAII C Station can be used in c
13. and Hazards Proof that a product complies with the directives is indicated by e the CE marking appearing on the rear of the product e the documentation package that accompanies the product containing a copy of the declaration of conformity This declaration is the legal declaration by Varian Inc that the product complies with the directives and also shows the EN standards to which the product was tested to demonstrate compliance The declaration of conformity is signed by the representative of the manufacturing plant cTUVus U S and Canadian Product Approvals The QAII C Station has been designed to comply with North American safety requirements This product has been tested and certified for the North American market by TUV Rheinland of North America Inc The TUVus mark signifies that this product has been tested to U S standards and certified for the U S market The cTUV mark signifies that this product has been tested to Canadian standards and certified for the Canadian market When the two marks are coupled the cTUVus mark signifies that this product has been tested to standards and certified for both markets WEEE Directive All Varian products that are subject to the WEEE directive shipped after August 13 2005 are compliant with the WEEE marking requirements Such products are marked with the crossed out wheelie bin WEEE symbol shown on page 12 in accordance with European Standard EN 50419 This symbol on the pr
14. calibration shaft and all the cables from the shipping carton Step 3 Remove as much cushioning material and tape as possible Varian Inc Page 20 QAII C Station Revision E 11 10 Installation and Setup Operator s Manual P N 70 9040 Step 4 Place the base unit and accessories on a clear dry level section of the bench top close to the dissolution apparatus The preferred placement of the QAII C Station is on the right side of the dissolution apparatus Warning A The electrical connection at the back of the instrument is the primary disconnect The instrument should be positioned to allow accessibility to the power cord for easy disconnection QAII C Attachments The QAII C comes with attachments necessary to measure and document individual spindle speeds shaft wobble shaft perpendicularity temperature instrument level and vibration Digital Wobble Gauge Mounted on a self aligning bracket the EaseAlign mounting bracket the wobble gauge has a built in display screen and shows wobble in terms of inches or millimeters A power switch preserves the life of the lithium battery The ORIGIN button makes it easy to zero the gauge prior to starting the spindles A cable transmits the gauge reading to the QAII C Station base unit FIGURE 2 Digital Wobble Gauge EaseAlign mounting bracket Varian Inc Page 21 QAII C Station Installation and Setup Revision E 11 10 Operator s Manual
15. displays Step 5 Select option 1 Print The QAII C System Setup Report prints The QAII C Test Report QAII C Temperature Report and QAII C Vibration Analysis Report print only as they are acquired Data is not stored on the QAII C for future printing Varian Inc Page 66 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 This page was intentionally left blank except for this message Varian Inc chapters Maintenance and Troubleshooting Periodic Maintenance Warning The QAII C contains electrical circuits devices and components operating at dangerous voltages Contact with these circuits devices and components can cause death serious injury or painful electric shock Periodic maintenance needs may vary depending on frequency of instrument usage Calibration We recommend the QAII C Station be calibrated at six month intervals However based on your own SOPs this can be extended for up to a year Call the Dissolution Systems Service Department for a quote packing instructions and a Return Authorization Number before sending your unit for recalibration Varian Inc Page 68 QAII C Station Revision E 11 10 Maintenance and Troubleshooting Operator s Manual P N 70 9040 Report Center Impact Printer The following is helpful information for using your impact printer Installing the Cartridge Ribbon If the printer is used infrequently the print im
16. through a window in the fuse compartment door To change the voltage gently pull the wheel to remove it from the holder Rotate the wheel and snap it back in place displaying the correct voltage Push the fuse compartment door closed It snaps into place Replace the power cord Varian Inc Page 74 Maintenance and Troubleshooting QAII C Station Operator s Manual Revision E 11 10 P N 70 9040 Troubleshooting The Dissolution Systems Service Department can assist you if you experience problems or have questions concerning your QAII C Many problems can be traced to simple sources and are easily solved Following is a troubleshooting guide which may help you The Dissolution Systems Service Department can be reached at 800 229 1108 inside the US or 919 677 1108 outside the US Optionally you can send a fax to 919 677 1138 You can also e mail the Dissolution Systems Service Department at dissolution service varianinc com Symptom Probable Cause Suggested Solution The unit does not respond when the main There is a blown fuse Replace the fuse See Fuse Replacement on page 73 power switch is turned on The unit is not plugged in Check the rear panel AC power cord receptacle Plug in the power cord The unit does not respond when the battery switch is turned on The battery is dead Recharge the battery See Power Switch Functions on page 24 The Report C
17. to be tested Lower the drive unit until there is a distance of approximately 1 cm from the top of the paddle blade to the top of the vessel or adapter Place the EaseAlign mounting bracket with the magnetic tachometer sensor and digital wobble gauge on the first vessel position to be tested The locating holes in the self aligning mounting bracket slip over the locating pegs see locating pegs in Figure 11 on page 30 Press down until the mounting bracket is level and firmly seated Varian Inc Page 50 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Step 5 The tip of the wobble gauge pointer should be positioned against the paddle shaft Step 6 Place the magnetic clip on the paddle shaft being checked see Figure 15 Placement for RPM Reading Paddle below To avoid damage to the paddle shaft place the clip at or near the top of the shaft just below the spindle chuck or drive unit then slide it down into its operating position in front of the tachometer sensor FIGURE 15 Placement for RPM Reading Paddle a magnetic clip in front of tachometer sensor Step 7 On the dissolution apparatus set the shafts to rotate at the desired speed and activate the spindles Varian Inc Revision E 11 10 QAII C Station Page 51 P N 70 9040 Operator s Manual Operation Step 8 Press CLEAR to skip this reading and move to the next spe
18. unit vibration along the X axis The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays DRIVE UNIT VIB X g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt CLEAR gt TO REMEASURE lt ENTER gt TO CONTINUE Step 5 Press CLEAR to remeasure the drive unit vibration along the X axis Repeat step 4 Optionally press ENTER to continue The following screen displays DRIVE UNIT VIB Y g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Varian Inc Page 62 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Step 6 Position the sensing arrow in the direction of the y axis Step 7 Press CLEAR to skip the y axis vibration reading or press PRINT to print the drive unit vibration along the Y axis The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays DRIVE UNIT VIB Y g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt CLEAR gt TO REMEASURE lt ENTER gt TO CONTINUE Step 8 Press CLEAR to remeasure the drive unit vibration along the Y axis Repeat step 7 Optionally press ENTER to continue The following screen displays DRIVE UNIT VIB Z g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt PRINT gt TO ACCEPT lt CLEA
19. your PC prior to beginning a test Step 1 Ensure the spreadsheet has been installed see Spreadsheet Installation on page 27 Varian Inc Revision E 11 10 QAII C Station Page 37 P N 70 9040 Operator s Manual Operation Step 2 Click Start on the Windows toolbar and select Programs gt Varian gt QAII C gt QAII C Template to open the file Microsoft Excel opens The Microsoft Excel window displays Step 3 Click Enable Macros Running a Test To run a test complete the following steps Step 1 Step 2 Step 3 From the monitor screen press TEST The Save As window displays If applicable select a file location Enter a file name and click Save The following screen displays Enter Apparatus ID XXXXXXXXXX 09 30 2004 15 37 37 Enter the dissolution apparatus identification number and press ENTER The Test Menu screen displays TEST MENU 1 PHYSICAL PARAMETER 2 TEMPERATURE 09 30 2004 15 37 37 Varian Inc Page 38 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Entering Physical Parameters Baskets If you are using paddles see Entering Physical Parameters Paddles on page 48 From the Test Menu screen select option 1 Physical Parameter The Step 1 following screen displays ENTER APPARATUS TYPE 1 BASKET 2 PADDLE 09 30 2004 15 37 37 Step 2 Select option 1 Basket The following screen displays SHAFT
20. 11 10 Maintenance and Troubleshooting Operator s Manual P N 70 9040 Step 9 While holding the paper in place press the printer toggle switch to the Paper feed position and hold until approximately one inch of paper has emerged from the top of the printer Caution Ensure the roll of paper feeds squarely If it does not the paper can jam and possibly damage the printer mechanism Step 10 Release the printer toggle switch Step 11 Turn the paper roll to take up any slack in the paper feeding to the printer Step 12 Place the paper roll into the paper compartment Step 13 Replace the paper roll cover If the cover is difficult to remove or replace the left and right edges can be trimmed or shaved with a utility knife allowing the cover to slide easier Step 14 Toggle the printer online by pressing the printer toggle switch to the OnLine Off Line position The Ready LED illuminates Toggling Your Printer Online Complete these steps to toggle your printer online Step 1 Step 2 Toggle the printer online by pressing the printer toggle switch to the OnLine Off Line position When the printer is off line the Ready LED does not illuminate Release the switch and it returns to the center position The Ready LED illuminates and a READY message prints if the PRINT READY command has not been turned off See Printer Configuration on page 71 for Varian Inc Revision E 11 10 QAII C Station Page 71 P N 70 9040
21. ID _ FOR POSITION 15 37 37 09 30 2004 Step 3 Enter the identification number for the basket shaft in position 1 and press ENTER The following screen displays VESSEL ID _ FOR POSITION 15 37 37 09 30 2004 Varian Inc Revision E 11 10 P N 70 9040 QAII C Station Page 39 Operator s Manual Operation Step 4 Step 5 Enter the identification number for the vessel in position 1 and press ENTER The following screen displays SPEED LVL 1 xx RPM POS IS xxx xx RPM lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Continue to Measuring RPM Basket below Measuring RPM Basket Note cI __Before beginning operation the dissolution apparatus must be set up with the basket shafts at their proper operating heights Step 1 Step 2 Step 3 Step 4 Step 5 If using a VK 7000 7010 raise the drive unit to remove the EaseAlign centering rings from the vessels to be tested Lower the drive unit until there is a distance of approximately 1 cm from the bottom rim of the basket to the top of the vessel or adapter Place the EaseAlign mounting bracket with the magnetic tachometer sensor and digital wobble gauge on the first vessel position to be tested The locating holes in the self aligning mounting bracket slip over the locating pegs see locating pegs in Figure 11 on page 30 Press down until the mounting bracket i
22. Operator s Manual Maintenance and Troubleshooting instructions on turning on and off the PRINT READY command When you first turn on the instrument it prints a READY message to assure you that the built in microprocessor is operating properly When you turn off the printer wait at least three seconds before turning it on again Printer Self Test You can test the print head and ribbon only after inserting paper Do not attempt to print without paper Follow these steps to perform a printer self test Step 1 Turn off the QAII C Station Step 2 Press and hold the printer toggle switch in the Paper feed position Step 3 Turn on the QAII C Station Step 4 Hold the printer toggle switch until printing begins The printer prints a list of the current configuration settings and performs a continuous print test Step 5 Press the printer toggle switch to the OnLine Off Line position to stop the printing operation Step 6 The printer is ready to resume normal operation Printer Configuration Note The printer configuration is set by the factory This procedure d 3 should be performed only if the printer displays erroneous characters Contact the Dissolution Systems Service Department for assistance if necessary Step 1 Turn off the QAII C Station Varian Inc Page 72 Maintenance and Troubleshooting QAII C Station Operator s Manual Revision E 11 10 P N 70 9040 Step 2 Step
23. R gt TO SKIP Step 9 Position the sensing arrow in the direction of the z axis Step 10 Press CLEAR to skip the z axis vibration reading or press PRINT to print the drive unit vibration along the Z axis The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays DRIVE UNIT VIB Z g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt CLEAR gt TO REMEASURE lt ENTER gt TO CONTINUE Varian Inc Revision E 11 10 QAII C Station Page 63 P N 70 9040 Operator s Manual Operation Step 11 Press CLEAR to remeasure the drive unit vibration along the Z axis Repeat step 10 Optionally press ENTER to continue The following screen displays PRESS lt ENTER gt TO COMPLETE TEST Step 12 Press ENTER The report footer prints The monitor screen displays see page 26 Step 13 Stop the spindles Printing Temperatures for Vessel Positions Step 1 Step 2 Step 3 From the Test Menu screen select option 2 Temperature The following screen displays VESSEL ID _ FOR POSITION 09 30 2003 15 37 37 Enter the identification number for the vessel in position 1 and press ENTER The following screen displays TEMP POS XX X C lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Ensure the temperature probe is in the vessel being measured Varian Inc Page 64 Operatio
24. Station has a main power switch and a battery power charge switch The main power switch is located on the back panel See Figure 10 QAII C Station Rear Panel on page 25 With the switch in the ON position the QAII C Station is on and you can charge the battery and print The battery power charge switch is on the left side panel When AC power is not present such as when the power cord is not attached or when the main switch is off the battery power charge switch allows battery power for data collection and monitoring If the AC power is on the battery power charge switch is used to charge the battery only It is recommended that you fully discharge the battery before the next charge to extend the battery life When the power is weak leave the battery switch on overnight without AC power This drains the remaining power so that it can be recharged Each charge period takes five to six hours Note that the Report Center Printer can be operated only with AC power Varian Inc Revision E 11 10 QAII C Station Page 25 P N 70 9040 Operator s Manual Installation and Setup Setting up the QAII C FIGURE 10 QAII C Station Rear Panel RPM LEVEL VIBRA RUNOUT SENSOR SENSOR SENSOR SENSOR SO Warning Ensure the AC power setting is at the correct voltage for your power supply The power setting is displayed on the back of the instrument on the line fuse holder located next to the power switch To change t
25. The following screen displays VESSEL TABLE VIB X g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 4 Continue to Measuring Vessel Plate Table Vibration on page 58 Varian Inc QAII C Station Revision E 11 10 P N 70 9040 Page 58 Operator s Manual Operation Measuring Vessel Plate Table Vibration Complete the following steps to record the vessel plate vibration Place the vibration sensor on the vessel plate as shown below to obtain readings Step 1 FIGURE 18 Vibration Sensor On the dissolution apparatus set the shafts to rotate at the desired Step 2 speed and activate the spindles Note For highest accuracy vessel table vibration should be read with I gt the drive unit in the operating position and the shafts rotating at 100 RPM And if possible the vessels should be filled with 900 mL of dissolution medium Step 3 Position the sensing arrow in the direction of the x axis Varian Inc Revision E 11 10 QAII C Station Page 59 P N 70 9040 Operator s Manual Operation Step 4 Press CLEAR to skip the x axis vibration reading or press PRINT to print the vessel table vibration along the X axis The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays VESSEL TABLE VIB X g x xxx FRQ xxx xx Hz
26. V xx xx mm S DS xxxx mm lt CLEAR gt TO REMEASURE lt ENTER gt TO CONTINUE Step 5 Press CLEAR to remeasure the vessel table vibration along the X axis Repeat step 4 Optionally press ENTER to continue The following screen displays VESSEL TABLE VIB Y g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 6 Position the sensing arrow in the direction of the y axis Step 7 Press CLEAR to skip the y axis vibration reading or press PRINT to print the vessel table vibration along the Y axis The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays VESSEL TABLE VIB Y g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt CLEAR gt TO REMEASURE lt ENTER gt TO CONTINUE Varian Inc Page 60 Operation QAII C Station Revision E 11 10 Operator s Manual P N 70 9040 Step 8 Step 9 Step 10 Step 11 Step 12 Step 13 Press CLEAR to remeasure the vessel table vibration along the Y axis Repeat step 7 Optionally press ENTER to continue The following screen displays VESSEL TABLE VIB Z g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Position the sensing arrow in the direction of the z axis Press CLEAR to skip the z axis vibration reading or press PRINT to print the vessel table
27. alues 76 Service and Warranty 77 Exclusions and Limitations 78 Obtaining Warranty Service 78 Warranty Limitations 78 Exclusive Remedies 79 Index 81 Tell Us How We Are Doing 83 Varian Inc Table of Contents This page was intentionally left blank except for this message Varian Inc List of Figures FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 QAII C Station 16 Digital Wobble Gauge 20 Magnetic Tachometer Sensor 21 Magnetic Clip 21 Universal Adapter 22 Electronic Level Sensor 22 Electronic Vibration Sensor 23 Temperature Probe 23 Line Fuse Holder and Main Power Switch 24 QAII C Station Rear Panel 25 Varian Inc List of Figures FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 EaseAlign Mounting Bracket Secured to Dissolution Apparatus 30 Placement for RPM Reading Basket 40 Wobble Gauge with Basket 44 Electronic Level Sensor Placement 45 Placement for RPM Reading Paddle 50 Wobble Gauge with Paddle 53 Electronic Level Sensor Placement 54 Vibration Sensor 58 Varian Inc chapter1 Safety Practices and Hazards The QAII C Station has been carefully designed so that when used properly you have an accurate fast flexible and safe instrument If the equipment is used in a manner not specified by the manufacturer the protection
28. d cautions carefully and observe them at all times Caution A Caution message appears in the manual when failure to observe instructions could result in damage to equipment Varian supplied and or other associated equipment A Note appears in the manual to give advice or information Varian Inc Page 12 QAII C Station Revision E 11 10 Safety Practices and Hazards Operator s Manual P N 70 9040 Information Symbols Switches main power on Switches main power off Indicates single phase alternating current Indicates the product complies with the requirements of one C or more European Union EU directives _ Indicates specific equipment meets consensus based IN standards of safety to provide assurance required by amp Ss OSHA that these products are safe for use in the workplace O a mot us for North America Indicates that this product must not be disposed of as unsorted municipal waste see WEEE Directive on page 13 General CE Compliant Products The QAII C Station has been designed to comply with the requirements of the Electro magnetic Compatibility EMC Directive and the Low Voltage Directive LVD of the EU Varian Inc has confirmed that each product complies with the relevant directives by testing a prototype against the prescribed European Norm EN standards Varian Inc Revision E 11 10 QAII C Station Page 13 P N 70 9040 Operator s Manual Safety Practices
29. ed value or press PRINT to print the speed reading The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays SPEED LVL 1 xx RPM POS IS xxx xx RPM lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Step 9 Press CLEAR to remeasure this speed reading Repeat step 8 Optionally press ENTER to continue to the next speed reading The following screen displays the next speed reading SPEED LVL 2 xx RPM POS IS xxx xx RPM lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 10 On the dissolution apparatus set the RPM to the next desired speed and activate the spindles Step 11 Repeat steps 8 10 for all speed readings Step 12 After the last value prints the following screen displays PADDLE SHAFT WOBBLE POSITION xx xx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 13 Continue to Measuring Wobble Paddle on page 52 Varian Inc Page 52 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Measuring Wobble Paddle Note For highest accuracy runout readings should be recorded with shafts turning at 50 RPM or less The paddle shaft wobble value as measured by the wobble gauge in either millimeters or inches is the absolute difference between I high and low values After zeroing the gauge the reading on the gauge s display screen may be negative or positive since there is
30. emedies The remedies provided herein are the customer s sole and exclusive remedies In no event shall Varian Inc or its representatives be liable for any direct indirect special incidental or consequential damages whether based on contract tort or any other legal theory Some states or provinces do not allow the exclusion or limitation of incidental or consequential damages so the above limitation or exclusion may not apply to you Varian Inc Page 80 QAII C Station Revision E 11 10 Service and Warranty Operator s Manual P N 70 9040 This page was intentionally left blank except for this message Varian Inc Index a apparatus without easealign centering rings 30 b base unit 16 baskets entering physical parameters 38 c calibration 67 cartridge ribbon 68 conventions 17 d default values 76 e entering physical parameters baskets 38 paddles 48 exclusions 78 exclusive remedies 79 f fuse replacement 73 h hazards 9 i installing the printer cartridge ribbon 68 introduction 15 level sensor 22 level measuring 57 limitations 78 m magnetic clip 21 measuring rpm for baskets 39 measuring rpm for paddles 49 o obtaining warranty service 78 operating the qaii c 31 Varian Inc Index p paddles entering physical parameters 48 periodic maintenance 67 physical parameters baskets 38 paddles 48 printer configuration 71 printer self test 71 pri
31. enter Printer does not function The printer is disabled Ensure the Report Center Printer is online and the Ready LED is illuminated See Toggling Your Printer Online on page 70 The QAII C is not plugged in or the main power switch is not turned on Plug the instrument into a wall outlet and ensure the main rear panel power switch is in the ON position The Report Center Printer is active but nothing prints The ribbon needs to be replaced Install a replacement ribbon cartridge See Installing the Cartridge Ribbon on page 68 The RPM readings are erratic The reflective clip is not registering Align the clip with the sensor The RPM sensor is not reading The sensor is not plugged into the QAII C rear panel or has come loose Restore connections Varian Inc Revision E 11 10 QAII C Station Page 75 P N 70 9040 Operator s Manual Maintenance and Troubleshooting Symptom Probable Cause Suggested Solution The wobble gauge is not reading The sensor is not plugged into the QAII C rear panel or has come loose Restore connections The pointer is not touching the shaft or rim of the basket Realign the mounting bracket The wobble gauge is not turned on Turn on the wobble gauge The level sensor is not reading The sensor is not plugged into the QAII C rear panel or has come loose Restore connections The
32. ext speed reading SPEED LVL 2 xx RPM POS IS xxx xx RPM lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 10 On the dissolution apparatus set the RPM to the next desired speed and activate the spindles Step 11 Repeat steps 8 10 for all speed readings Step 12 After the last value prints the following screen displays BASKET SHAFT WOBBLE POSITION xx xx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 13 Continue to Measuring Wobble Basket on page 42 Varian Inc Page 42 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Measuring Wobble Basket Note For highest accuracy runout readings should be recorded with shafts turning at 50 RPM or less The basket shaft wobble value as measured by the wobble gauge in either millimeters or inches is the absolute difference between high and low values After zeroing the gauge the reading on the gauge s display screen may be negative or positive since there is no way for the unit to determine whether you placed the gauge pointer on the shaft s high point low point or somewhere in between For example if the reading ranges between 0 05 mm and 0 1 mm the QAII C Station displays the runout value as 0 15 mm Complete the following steps to record the shaft or basket rim wobble Step 1 Press ON OFF on the wobble gauge The display screen activates Step 2 Press in mm on the gauge key to select inches o
33. he voltage see Fuse Replacement on page 73 The electrical connection at the back of the instrument is the primary disconnect Step 1 Ensure the main power switch and the side panel power switch are in the off positions Step 2 Connect the cables between the remote sensors and their corresponding jacks on the QAII C rear panel See Figure 10 QAII C Station Rear Panel above Each cable has a different kind of connector making it impossible to plug it into the wrong jack Varian Inc Page 26 QAII C Station Revision E 11 10 Installation and Setup Operator s Manual P N 70 9040 Step 3 Connect the RS232 cable between the RS232 port on the QAII C rear panel and the serial com01 port on the back of the PC Step 4 Connect the AC power cord between the power receptacle on the QAII C rear panel and an AC electrical outlet of the appropriate voltage Note AC power is necessary for battery charging or printing Step 5 Turn on the QAII C The following screen displays for three seconds VARIAN INC QA II C TEST STATION PROGRAM REV x xx 09 30 2004 15 37 37 Step 6 The firmware version displays This is the only time the firmware revision level displays Record the number below and refer to it if you need to call the Dissolution Systems Service Department Firmware version Step 7 The monitor screen displays RPM xxx xx TEMP xx x WOB xx xx VIB x xxx LV X xx
34. inue to Measuring Temperature Basket below Measuring Temperature Basket Complete the following steps to record the vessel medium temperature Step 1 Step 2 Step 3 Ensure the temperature probe is in the vessel being measured Press CLEAR to skip the vessel temperature for this vessel position or press PRINT to print the vessel temperature The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays TEMP POS XX X C lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Press CLEAR to remeasure the vessel temperature Repeat step 2 Optionally press ENTER to continue The following screen displays SHAFT ID _ FOR POSITION 09 30 2003 15 37 37 Varian Inc Revision E 11 10 QAII C Station Page 47 P N 70 9040 Operator s Manual Operation Step 4 Repeat this entire procedure from step 3 under Entering Physical Parameters Baskets on page 38 for each vessel position Step 5 After the last value prints the following screen displays VESSEL TABLE LEVEL LV X XxX X LV Y xx x lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 6 Continue to Measuring Vessel Plate Table Level on page 57 Varian Inc Page 48 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Entering Physical Parameters Paddles If you are using baskets
35. level sensor displays erratic readings The sensor is not in the upright position Correct the positioning The vibration sensor is not reading The sensor is not plugged into the QAII C rear panel or has come loose Restore connections There is excessive wobble The paddle or basket shaft is damaged Verify the spindle wobble is within specifications using the certified calibration shaft The shaft verticality or perpendicularity is excessive The paddle or basket shaft is damaged Verify the spindle perpendicularity is within specifications using the certified calibration shaft The drive unit is not level Contact the Dissolution Systems Service Department The spindle is not centered Contact the Dissolution Systems Service Department Varian Inc Page 76 QAII C Station Revision E 11 10 Maintenance and Troubleshooting Operator s Manual P N 70 9040 QAII C Default Values The default value prints for any sensor which is not plugged into the unit during testing The values listed below apply for both standard and metric units see Measuring Wobble Basket on page 42 Measuring Wobble Paddle on page 52 and Main Menu Option 1 Setup on page 32 for instructions on selecting inches or millimeters for wobble and vibration respectively Note CN gt If any of the following default values display ensure all connections are tight
36. m ap aS VARIAN Copyright c 2003 2010 by Varian Inc Table of Contents Chapter 1 Safety Practices and Hazards 9 Electrical Hazards 10 Other 10 General 12 WEEE Directive 13 Chapter 2 Introduction 15 Base Unit 16 Conventions Used in this Manual 17 Chapter 3 Installation and Setup 19 Unpacking Your QAII C Station 19 QAII C Attachments 20 Digital Wobble Gauge 20 Varian Inc Table of Contents Chapter 4 Chapter 5 Magnetic Tachometer Sensor 21 Magnetic Clip 21 Universal Adapter 22 Electronic Level Sensor 22 Electronic Vibration Sensor 23 Temperature Probe 23 Power Switch Functions 24 Setting up the QAII C 25 Spreadsheet Installation 27 Operation 29 Placing the Universal Adapter on Apparatus without EaseAlign Centering Rings 30 Operating the QAII C Station 31 Main Menu Option 1 Setup 32 Main Menu Option 2 Vibration 36 Opening the Spreadsheet optional 36 Running a Test 37 Entering Physical Parameters Baskets 38 Entering Physical Parameters Paddles 48 Printing Temperatures for Vessel Positions 63 Printing Test Setup 65 Maintenance and Troubleshooting 67 Periodic Maintenance 67 Calibration 67 Report Center Impact Printer 68 Installing the Cartridge Ribbon 68 Replacing the Paper Roll 69 Toggling Your Printer Online 70 Printer Self Test 71 Printer Configuration 71 Varian Inc Table of Contents Chapter 6 Fuse Replacement 73 Troubleshooting 74 QAII C Default V
37. n QAII C Station Revision E 11 10 Operator s Manual P N 70 9040 Step 4 Step 5 Step 6 Press CLEAR to skip the vessel temperature reading for position 1 and move to the next position The Enter Vessel ID screen displays Repeat steps 2 3 for the next vessel position Optionally press PRINT to print the vessel temperature reading The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays TEMP POS XXx X C lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Press CLEAR to remeasure the vessel temperature for this position Repeat step 4 Optionally press ENTER to continue to the next vessel position The Enter Vessel ID screen displays Repeat steps 2 4 Repeat this procedure for each vessel position After the final vessel temperature is measured the monitor screen displays see page 26 Varian Inc Revision E 11 10 QAII C Station Page 65 P N 70 9040 Operator s Manual Operation Printing Test Setup To print the test setup complete the following steps Step 1 Ensure the QAII C Station is plugged into AC power with the main rear panel power switch in the ON position Step 2 From the monitor screen press MENU The QA II C Main Menu screen displays Step 3 Select option 1 Setup The System Setup screen displays Step 4 Select option 2 Print Setup The Test Setup Report screen
38. ne number here Please return this form via mail to Technical Writing Dissolution Systems Varian Inc 13000 Weston Parkway Cary North Carolina 27513 2250 USA Optionally you can return this form via fax at 1 919 677 1550 Always feel free to telephone us to discuss your comments at 1 800 229 1108 QAII C Station Operator s Manual P N 70 9040 Revision E
39. ng Step 7 Toggle the printer online by pressing the printer toggle switch to the OnLine Off Line position The Ready LED illuminates Step 8 Replace the paper if necessary If you get ribbon ink on the printer s plastic cover remove it immediately Once dried it is difficult to remove Replacing the Paper Roll Step 1 Step 2 Step 3 Step 4 Step 5 Step 6 Step 7 Step 8 Toggle the printer off line by pressing the printer toggle switch to the OnLine Off Line position When the printer is off line the Ready LED does not illuminate Grasp the paper roll cover firmly by the grooves on the side and the front edge Pull outward to remove the cover Press the printer toggle switch to Paper feed to advance the paper approximately one inch beyond the paper cutter Using scissors cut the paper feeding to the printer and remove the paper roll Pull the remaining paper through the printer mechanism Pull the paper from the front paper cutter side Pulling the paper out of the back of the printer will damage the print mechanism Unroll several inches of paper on the new roll If it is jagged cut a straight edge on the paper roll to facilitate the entry of the paper into the printer Slide the paper through the slot connecting the paper compartment and the printer compartment You can slide it in approximately 1 4 inch before it stops Varian Inc Page 70 QAII C Station Revision E
40. ng Shaft Verticality Basket This accessory is used in conjunction with a centering tool to verify proper shaft alignment Complete the following steps to record the shaft verticality Step 1 Stop the spindles Step 2 Hold the level sensor flush against the shaft The perpendicular groove of the sensor should be placed high up on the shaft approximately 1 inch or 25 4 mm below the bottom of the dissolution apparatus drive unit This sensor measures in degrees the verticality or perpendicularity of the shaft from side to side and front to back simultaneously See Figure 14 Electronic Level Sensor Placement below FIGURE 14 Electronic Level Sensor Placement y a Step 3 Press CLEAR to skip the basket shaft perpendicularity for this vessel position or press PRINT to print the basket shaft perpendicularity The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays BASKET SHAFT PERPEND POS X xx x Y XX X lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Varian Inc Page 46 Operation QAII C Station Revision E 11 10 Operator s Manual P N 70 9040 Step 4 Step 5 Press CLEAR to remeasure the basket shaft perpendicularity Repeat step 3 Optionally press ENTER to continue The following screen displays TEMP POS XX X C lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Cont
41. no way for the unit to determine whether you placed the gauge pointer on the shaft s high point low point or somewhere in between For example if the reading ranges between 0 05 mm and 0 1 mm the QAII C Station displays the runout value as 0 15 mm Complete the following steps to record the paddle shaft wobble Step 1 Press ON OFF on the wobble gauge The display screen activates Step 2 Press in mm on the gauge key to select inches or millimeters as the measurement unit Step 3 Press and hold briefly ORIGIN to zero the gauge The screen displays 0 0000 in or 0 00 mm Note ne It is not necessary to zero the wobble gauge before measuring and recording runout since the value recorded is the absolute difference between the high and low values Varian Inc Revision E 11 10 P N 70 9040 QAII C Station Page 53 Operator s Manual Operation Step 4 Ensure the wobble gauge is properly positioned with the tip of the wobble gauge pointer positioned against the paddle shaft See Figure 16 Wobble Gauge with Paddle below Caution To avoid damage to the EaseAlign mounting bracket when using Apparatus 2 check the clearance between the paddle blade and the bottom of the mounting bracket before rotating the shafts Step 5 On the dissolution apparatus set the desired speed and activate the spindles FIGURE 16 Wobble Gauge with Paddle Step 6
42. nter toggling online 70 printing test setup 65 r reader comment form 83 rear panel connections 25 rpm measuring for baskets 39 running a test 37 s safety practices 9 self test printer 71 service 77 setup 19 shaft verticality measuring for baskets 45 measuring for paddles 54 system setup 32 t tachometer sensor 21 temperature measuring for baskets 46 measuring for paddles 55 temperature probe 23 temperature printing 63 troubleshooting 74 u universal adapter 22 30 unpacking your qaii c 19 v vibration 36 vibration sensor 23 vibration measuring drive unit 61 vibration measuring vessel table 58 w warranty 77 warranty limitations 78 wobble gauge 20 wobble measuring for baskets 42 wobble measuring for paddles 52 Varian Inc Tell Us How We Are Doing We listen to our customers We work hard to make our technical documentation user friendly and to make the information in our manuals easy to retrieve and use We d like you to tell us the kinds of additional information you d find helpful in our documentation Your feedback will be carefully considered when we prepare future editions of this manual This manual should contain the following additional information The most useful thing about this book is This manual would be more helpful if My general impressions of this book are May we contact you regarding your comments YES NO If yes please write your name address and telepho
43. nu screen System Setup Option 1 Test Setup After selecting option 1 Test Setup from the System Setup screen complete the following steps Step 1 Enter the number of spindle positions to be tested on the dissolution apparatus and press ENTER The RPM screen displays Step 2 To skip RPM select option 2 No and continue to step 6 To include RPM in the test select option 1 Yes The following screen displays SPD 1 4 _ 09 30 2004 15 37 37 Varian Inc Page 34 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Step 3 The QAII C allows you to test each spindle location at up to 4 user defined speeds RPM Enter the number of speed levels to test 1 4 and press ENTER The following screen displays SPD LVL1 _ ENTER 15 TO 250 09 30 2004 15 37 37 Step 4 Enter the RPM to test as level 1 and press ENTER Step 5 Repeat step 4 for each subsequent speed level as entered in step 3 After entering the final speed level the Wobble screen displays Step 6 To skip wobble select option 2 No and continue to step 8 To include wobble in the test select option 1 Yes The Bskt Wobble screen displays Step 7 Select option 1 Rim and Shaft to measure wobble on the basket rim and shaft for Apparatus 1 baskets or to measure paddle shaft wobble for Apparatus 2 paddles To measure wobble on the basket rim only for Apparatus 1 select option 2 Rim Only The Shaft Pe
44. oduct or on its packaging indicates that this product must not be disposed of as unsorted municipal waste The separate collection and recycling of your waste equipment at the time of disposal will help to conserve natural resources and ensure that it is recycled in a manner that protects human health and the environment For more information on collection reuse and recycling systems please contact your local regional waste administration your local distributor or Varian Inc Varian Inc Page 14 QAII C Station Revision E 11 10 Safety Practices and Hazards Operator s Manual P N 70 9040 This page was intentionally left blank except for this message Varian Inc chapter2 Introduction The QAII C Station is designed to help you easily check the critical physical parameters specified in the USP General Chapters lt 711 gt Dissolution and lt 724 gt Drug Release The QAII C Station tests and documents the parameters of the following variables e shaft wobble also known as runout e instrument level e vessel temperature e spindle speed e vibration Regulatory authorities emphasize these factors since they can lead to major variances in your dissolution results The QAII C Station can be used as a standalone data acquisition and printing station Test data can be printed via the Report Center Printer or if desired downloaded via RS232 to a spreadsheet application for storage on a personal computer The QAII C S
45. onjunction with any Varian dissolution apparatus including older models or with any non Varian dissolution apparatus For dissolution apparatus that do not have EaseAlign centering rings the QAII C Station comes with a universal adapter This adapter mounts to the dissolution apparatus vessel in the same manner as the EaseAlign centering rings Once this adapter is in place the procedures for using the QAII C Station are the same for all dissolution apparatus The purpose of the adapter is to provide the locating pegs to secure the EaseAlign mounting bracket to the dissolution apparatus see locating pegs in Figure 11 on page 30 Varian Inc Page 30 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 FIGURE 11 EaseAlign Mounting Bracket Secured to Dissolution Apparatus EaseAlign mounting locating o bracket pegs Placing the Universal Adapter on Apparatus without EaseAlign Centering Rings Note _ Before beginning operation the dissolution apparatus must be set up with the paddles or basket shafts at their proper operating heights Step 1 Raise the dissolution apparatus drive unit Step 2 Position the universal adapter over the vessel and push down gently so the adapter is held in place by the short legs that rest against the inside of the vessel The bracket should fit without having to be forced and it should sit flat on the dissolution apparatus vessel plate
46. ould seriously damage the instrument and any attached ancillary equipment Always use a three wire outlet with ground connection which is adequately rated for the load The installation must comply with local state and federal safety regulations Do not connect the instrument to the main power supply until you have made sure that the operating voltage is correctly set for the main power supply in the specific outlet in your laboratory to which the equipment will be connected Other Other specific warnings and cautions appear in the manuals where appropriate and detail the specific hazard describe how to avoid it and specify the possible consequences of not heeding the warning or caution Warning A Warning message appears in the manual when failure to observe instructions or precautions could result in death or injury Symbols depicting the nature of the specific hazard are also placed alongside warnings Varian Inc Revision E 11 10 QAII C Station Page 11 P N 70 9040 Operator s Manual Safety Practices and Hazards These symbols may be used on warning labels attached to the instrument When you see one of these symbols you must refer to the relevant operation or service manual for the correct procedure referred to by that warning label The meaning of the symbols that appear alongside warnings in this manual are as follows Electrical shock A Caution Refer to accompanying documents Read all warnings an
47. pression sometimes becomes weak because the ribbon dries out If the printed material is difficult to read and you suspect this is the cause of the problem advance to a new section of the ribbon by pressing the printer toggle switch to the Paper feed position If the printing is still faint replace the cartridge To install the cartridge Step 1 Toggle the printer off line by pressing the printer toggle switch to the OnLine Off Line position When the printer is off line the Ready LED does not illuminate Step 2 Four small grooves are embossed on the printer cover Gently push on these grooves to tilt the cover When the printer cover is tilted up you can lift it off completely Step 3 Push down on the right side of the ribbon cartridge marked PUSH and remove the old cartridge Step 4 Install the new cartridge If there is already paper in the printer hold the cartridge between your thumb and index finger slide it over the paper and into the printer compartment Ensure the paper is between the ribbon cartridge and the ink ribbon Ensure the ink cartridge is inserted firmly to prevent weak or irregular printing The cartridge must be properly seated and aligned for the best printing Step 5 Turn the cartridge knob marked by an arrow clockwise to stretch the ribbon taut Step 6 Replace the cover Varian Inc Revision E 11 10 QAII C Station Page 69 P N 70 9040 Operator s Manual Maintenance and Troubleshooti
48. r is now configured correctly Varian Inc Revision E 11 10 QAII C Station Page 73 P N 70 9040 Operator s Manual Maintenance and Troubleshooting Fuse Replacement Warning A The QAII C Station contains electrical circuits devices and components operating at dangerous voltages Contact with these circuits devices and components can cause death serious injury or painful electric shock Panels or covers that are retained by fasteners which require the use of a tool for removal may be opened only by Varian trained Varian qualified or Varian authorized service engineers The fuse compartment is located beside the power cord receptacle on the QAII C rear panel See Figure 10 QAII C Station Rear Panel on page 25 Step 1 Step 2 Step 3 Step 4 Step 5 Step 6 Step 7 To check or replace the fuse remove the power cord from the QAII C A release tab is located on the right side of the fuse compartment Insert a slotted screwdriver under the tab A slight application of pressure forward releases the door The fuses are located in the removable holders marked with an arrow on the top of each The QAII C uses one 500 mAmp metric 5 x 20 mm standard fuse for each holder Replace the fuse in the holder and insert the fuse holder into the fuse compartment with the arrows pointing toward the bottom of the compartment The holder is designed for multiple voltages The voltage displays
49. r millimeters as the measurement unit Step 3 Press and hold briefly ORIGIN to zero the gauge The screen displays 0 0000 in or 0 00 mm e gt Note It is not necessary to zero the wobble gauge before measuring and recording runout since the value recorded is the absolute difference between the high and low values Step 4 Ensure the wobble gauge is properly positioned with the tip of the wobble gauge pointer positioned against the basket shaft Step 5 On the dissolution apparatus set the desired speed and activate the spindles Varian Inc Revision E 11 10 P N 70 9040 QAII C Station Page 43 Operator s Manual Operation Step 6 Step 7 Step 8 Step 9 Press CLEAR to skip the basket shaft wobble for this vessel position or press PRINT to print the basket shaft wobble The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays BASKET SHAFT WOBBLE POSITION xx xx mm lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Press CLEAR to remeasure the basket shaft wobble Repeat step 6 Optionally press ENTER to continue The following screen displays BASKET RIM WOBBLE POSITION xx xx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Stop the spindles Reposition the wobble gauge with the tip of the wobble gauge pointer positioned against the bottom
50. rect time in 24 hour format and press ENTER The QA II C Main Menu screen displays Main Menu Option 1 Setup From the QA II C Main Menu screen select option 1 Setup The System Setup screen displays SYSTEM SETUP 1 TEST SETUP 2 PRINT SETUP 3 UNIT 4 DATE FORMAT 5 COMM Following is a description of the System Setup screen options Option Response 1 Test Setup Select option 1 Test Setup to select the test parameters See System Setup Option 1 Test Setup on page 33 2 Print Setup Select option 2 Print Setup to print the system setup report The Test Setup Report screen displays Select option 1 to print the report see Printing Test Setup on page 65 Optionally select option 2 to cancel and return to the System Setup screen 3 Unit Select option 3 Unit to select the measurement unit Press 1 for metric or 2 for imperial The System Setup screen displays Varian Inc Revision E 11 10 P N 70 9040 QAII C Station Page 33 Operator s Manual Operation Option Response 4 Date Format Select option 4 Date Format to select the date format Select option 1 for mm dd yyyy 2 for dd mm yyyy or 3 for yyyy mm dd The System Setup screen displays 5 COMM Select option 5 Comm to select the communication configuration See System Setup Option 5 Comm on page 35 Press MENU to return to the QA II C Main Me
51. rim of the basket See Figure 13 Wobble Gauge with Basket on page 44 Caution When using Apparatus 1 it is necessary to reposition the runout gauge pointer to the bottom rim of the basket before obtaining a reading Take extra care to avoid damage to the runout gauge pointer When repositioning the drive unit for proper alignment with the lower rim of the basket use a thin ruler to hold the pointer safely away from your fingers Step 10 Activate the spindles Varian Inc Page 44 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 FIGURE 13 Wobble Gauge with Basket Step 11 Press CLEAR to skip the basket rim wobble for this vessel position or press PRINT to print the basket rim wobble The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays BASKET RIM WOBBLE POSITION xx xx mm lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Step 12 Press CLEAR to remeasure the basket rim wobble Repeat step 11 Optionally press ENTER to continue The following screen displays BASKET SHAFT PERPEND POS X xx x Y XX X lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 13 Continue to Measuring Shaft Verticality Basket on page 45 Varian Inc Revision E 11 10 QAII C Station Page 45 P N 70 9040 Operator s Manual Operation Measuri
52. rpend screen displays Step 8 To skip shaft perpendicularity select option 2 No To include shaft perpendicularity in the test select option 1 Yes The Temperature screen displays Step 9 To skip temperature select option 2 No To include temperature in the test select option 1 Yes The Level Vessel Table screen displays Step 10 To skip level of the vessel table select option 2 No To include level of the vessel table in the test select option 1 Yes The Vib Vessel Table screen displays Varian Inc Revision E 11 10 QAII C Station Page 35 P N 70 9040 Operator s Manual Operation Step 11 To skip vibration of the vessel table select option 2 No To include vibration of the vessel table in the test select option 1 Yes The Vib Drive Unit screen displays Step 12 To skip vibration of the drive unit select option 2 No To include vibration of the drive unit in the test select option 1 Yes The System Setup screen displays System Setup Option 5 Comm After selecting option 5 Comm from the System Setup screen complete the following steps Step 1 Step 2 Step 3 Step 4 Step 5 From the Comm Config screen select option 1 Com ID Enter the communication port identification number and press ENTER If you are running the supplied spreadsheet application the communication port identification number must be set to 1 The Comm Config screen displays Select option 2 Baud Rate The Set
53. s level and firmly seated The tip of the wobble gauge pointer should be positioned against the shaft of the basket assembly Varian Inc Page 40 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Step 6 Place the magnetic clip on the basket shaft being checked see Figure 12 Placement for RPM Reading Basket below To avoid damage to the basket shaft place the clip at or near the top of the shaft just below the spindle chuck or drive unit then slide it down into its operating position in front of the tachometer sensor FIGURE 12 Placement for RPM Reading Basket magnetic clip in front of tachometer sensor Step 7 On the dissolution apparatus set the shafts to rotate at the desired speed and activate the spindles Step 8 Press CLEAR to skip this reading and move to the next speed value or press PRINT to print the speed reading The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays SPEED LVL 1 xx RPM POS IS xxx xx RPM lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Varian Inc Revision E 11 10 QAII C Station Page 41 P N 70 9040 Operator s Manual Operation Step 9 Press CLEAR to remeasure this speed reading Repeat step 8 Optionally press ENTER to continue to the next speed reading The following screen displays the n
54. see Entering Physical Parameters Baskets on page 38 From the Test Menu screen select option 1 Physical Parameter The Step 1 following screen displays ENTER APPARATUS TYPE 1 BASKET 2 PADDLE 09 30 2003 15 37 37 Step 2 Select option 2 Paddle The following screen displays SHAFT ID _ FOR POSITION 15 37 37 09 30 2003 Step 3 Enter the identification number for the paddle shaft in position 1 and press ENTER The following screen displays VESSEL ID _ FOR POSITION 15 37 37 09 30 2003 Varian Inc Revision E 11 10 P N 70 9040 QAII C Station Page 49 Operator s Manual Operation Step 4 Step 5 Enter the identification number for the vessel in position 1 and press ENTER The following screen displays SPEED LVL 1 xx RPM POS IS xxx xx RPM lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Continue to Measuring RPM Paddle below Measuring RPM Paddle Caution To avoid damage to the EaseAlign mounting bracket check the clearance between the paddle blade and the bottom of the mounting bracket before running the test Note I gt Before beginning operation the dissolution apparatus must be set up with the paddle shafts at their proper operating heights Step 1 Step 2 Step 3 Step 4 If using a VK 7000 7010 raise the drive unit to remove the EaseAlign centering rings from the vessels
55. tation records the instrument identification numbers of the apparatus shafts and vessels in addition to test values Varian Inc Page 16 QAII C Station Revision E 11 10 Introduction Operator s Manual P N 70 9040 The built in printer provides a detailed hard copy report listing all parameter values for each vessel position If you use serialized paddles or basket shafts you can have these numbers print on the report as well Base Unit The QAII C Station base unit contains the keypad display screen and Report Center Printer The five remote sensors plug into the keyed jacks on the rear panel The base unit has a rechargeable battery for portable use and its own AC power supply for printing or charging the battery There is a power switch on the left side panel that controls the battery power to the unit and there is a power switch on the back panel that controls AC power to the unit You must operate under AC power in order to print via the Report Center Printer FIGURE 1 QAII C Station Caution Panels or covers that are retained by fasteners which require the use of a tool for removal may be opened only by Varian trained Varian qualified or Varian authorized service engineers Varian Inc Revision E 11 10 QAII C Station Page 17 P N 70 9040 Operator s Manual Introduction Conventions Used in this Manual e Items you are asked to press are in bold For example press TEST on the keypad
56. vibration along the Z axis The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays VESSEL TABLE VIB Z g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt CLEAR gt TO REMEASURE lt ENTER gt TO CONTINUE Press CLEAR to remeasure the vessel table vibration along the Z axis Repeat step 10 Optionally press ENTER to continue The following screen displays DRIVE UNIT VIB X g x xxx FRQ xxx xx Hz V xx xx mm S DS xxxx mm lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Stop the spindles Continue to Measuring Drive Unit Vibration on page 61 Varian Inc Revision E 11 10 QAII C Station Page 61 P N 70 9040 Operator s Manual Operation Measuring Drive Unit Vibration Complete the following steps to record the drive unit vibration Step 1 Place the vibration sensor on the drive unit Step 2 On the dissolution apparatus set the shafts to rotate at the desired speed and activate the spindles Note z For highest accuracy drive unit vibration should be read with the I gt drive unit in the operating position and the shafts rotating at 100 RPM And if possible the vessels should be filled with 900 mL of dissolution medium Step 3 Position the sensing arrow in the direction of the x axis Step 4 Press CLEAR to skip the x axis vibration reading or press PRINT to print the drive
57. w FIGURE 17 Electronic Level Sensor Placement Varian Inc Revision E 11 10 QAII C Station Page 55 P N 70 9040 Operator s Manual Operation Step 3 Press CLEAR to skip the paddle shaft perpendicularity for this vessel position or press PRINT to print the paddle shaft perpendicularity The values freeze on the screen print on the Report Center Printer and if applicable are transmitted to the spreadsheet The following screen displays PADDLE SHAFT PERPEND POS X xx x Y XX X lt ENTER gt TO CONTINUE lt CLEAR gt TO REMEASURE Step 4 Press CLEAR to remeasure the paddle shaft perpendicularity Repeat step 3 Optionally press ENTER to continue The following screen displays TEMP POS xx x C lt PRINT gt TO ACCEPT lt CLEAR gt TO SKIP Step 5 Continue to Measuring Temperature Paddle below Measuring Temperature Paddle Complete the following steps to record the vessel medium temperature Step 1 Ensure the temperature probe is in the vessel being measured Varian Inc Page 56 QAII C Station Revision E 11 10 Operation Operator s Manual P N 70 9040 Step 2 Press CLEAR to skip the vessel temperature for this vessel position or press PRINT to print the vessel temperature The value freezes on the screen prints on the Report Center Printer and if applicable is transmitted to the spreadsheet The following screen displays TEMP POS
58. xcluded are defects from improper or inadequate maintenance by the customer user induced chemical action or contamination unauthorized modification or misuse and improper site preparation and maintenance Operation of software is not warranted to be uninterrupted or error free Obtaining Warranty Service To obtain warranty service in the United States contact the Dissolution Systems Service Department at 800 229 1108 to obtain authorization to return units for repair At the option of the customer onsite warranty service is available but travel charges may be incurred The customer should prepay all shipping charges for products returned to the Dissolution Systems Service Department unless otherwise authorized and Varian Inc will pay all charges for return to the customer Warranty Limitations Varian Inc makes no other warranty either express or implied with respect to this product Specifically disclaimed are any implied warranties of merchantability and fitness for a particular use In no event will Varian Inc be liable for any indirect incidental or consequential damages arising from the use of this product This warranty gives you specific legal rights which may vary from state to state or province to province so you may have other rights and some of these exclusions may not apply to you Varian Inc Revision E 11 10 QAII C Station Page 79 P N 70 9040 Operator s Manual Service and Warranty Exclusive R

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