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1. XYZ Drive Mech Home pos LR CN4 X RELAY ON Y Z RELAY Detection CN6 VV FFO ew PCBNO 2134 a Detector block CN2 CN3 C CN2 CN3 PD BOARD _ PD2 BOARD PD BOARD PD2 BOARD EDTBDOARD 2132 PCBNO 2156 PCBNO 2132 21 y 92198 9259 d Sensor for Ext Temp N J PCBNO 2133 ii I M Z RELAY Y 4 Ly PCNO 9264 Detection cNi O CN2 Cover es M e Switch Thermo 4 22 Sensor CH2 CH1 X GEM i Heater S TONS m CH6 E CH5 E i Crush L Reagent Table Heater d M Sensor FUSE 3 i E i Z CH4 CH3 CNS J To S SS B Reagent Rack x Ll 9 1 Mi g Cooling Section Thermal Detector N Detection LED2 BOARD m PCNO 9258 Fan al Cooler N Pressure Pump Sample Table Table Table Detection Lock Sample Rack Detection Chamber Swich Volumetric mH Syri
2. 2 9 20 omm 2 9 2 9 BARCODE READER UNIT ID COMPLETED 2 10 2 9 1 2 10 2 9 2 SpeciNcatons FUNCIONS MNT DET 2 10 2 10 PUMP UNIT PRESSURE PUMP VACUUM PUMP COMPLETED PARTS 2 11 u 2 11 2 11 VALUES 2 11 CA 500 Series S M Revised December 2001 8 SECTION 2 HYDRAULIC MECHANICAL SYSTEMS 2 1 TUBING DIAGRAM Probe Rinse Cup Outside MAIN PCNo 6362 Probe Rinse Cup Inside Rubber Tube No 7 Si4 95 TF2 450 Trash SV No 14 Rinse Cup Si1 TF1 1600 620 Si2 240 LFAA 250 200 Volumetric Pipette Hydraulic Connector Piston TA TA No 23 Es 520 80 Vacuum TA 160 Rear Pane red L Si2 200 Check Valve y Si2 500 500 0 Trap Chamber 7Assy Pd Rinse Bottle Waste Bottle Si2 500 511 Tube Silicone 2 x 5 Si2 Tube Silicone 4 x 8 Si3 Tube Silicone 1 32 x 3 32 inches Si4 Tube Silicone 6 x 10 TF1 Tube Teflon 1 2 x 2 0 TF2 Tube Teflon 1 5 x 2 5 Tube Toalone 3 x 6 B Connect
3. _ THERMO echanical Touch Screen PCB WI PCB No 9258 PCB No 9263 tO LED2 LO Inverter VR N LED for Scattered LCD Contrast 2 Volume 2 9 z m m Volumetric Unit 209 O ss ve A No 9259 a LED1 Built in Printer LEDforTransmitted PCB No 9258 X Y Z Drive Mechanism x PCB No 2134 PCB No 9260 LEE PCB No 9265 PR RELAY Volumetric Operation Panel Surface Sensor Syringe Motor Syringe Motor Probe Crash SU Y Axis Home Pos Syringe Relay Pos Sensor Sensor X Axis TEE Drive Motor Drive Motor i PCB No 6350 Pressure Pump PRCN 2 Crash Switch Printer Control Board Vacuum Pump Z Axis Er Drive Motor Z Axis Home Pos Sensor Sample Pipette PCB pone 5 MEMORY ae Mixing Motor Program Memory Reagent Cooler Unit PCB No 6362 MAIN Thermister Cooling Fan PCB No 4086 CPU Ringe PS Motor Control Bottle Peltier Cooler Power Supply Temp Control BEEN Motor Drive AID Waste Sampler Bottle Sample Rack Sensor ID Unit Drive Motor ID Unit f Tapie 5232 Option Serial Port ID Unit Home Pos Sensor Table Lock Figure 3 2a CA 500 Electric Block Diagram 1 CA 50
4. Constant 1 05V while operating ao Sm gt Mixing motor ircui i Voltage Control Mixing Motor ON OFF Driver to Mixing motor 24V 24V GND to inverter for LCD f Detector Block heater 12V gt ON OFF FET to Detector Block heater Driver Peltier cooler ON OFF REL to Peltier cooler Driver gt 12V Peltier cooler fan GND f Solenoid Valve 1 12V4 ON OFF Driver T Solenoid Valve 1 TD62308 Solenoid Valve 2 ON OFF Driver Solenoid Valve 2 TD62308 Table Lock Driver 24 Transistor _ to Table Lock w registor Probe heater 24 6362 MAIN 6373 MAIN 2 ON OFF FET to Probe heater Driver Figure 3 8 PCB No 4086 Block Diagram to be continued 3 12 Revised December 2001 3 6 3 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 24V
5. 2 Current tol Low pass Amplifier _ 6362 PhD 2101900 Filter Section CH2 to PCB No 6373 MAIN 2 CH4 5 Voltage La Lowpass _ Amplifier to PCB No 6362 MAIN L Converter Filter mq to PCB No 6373 MAIN 2 S 7 s PhD OUS Lowpass Amplifier li to PCB No 6362 MAIN Converter Mecum E to PCB No 6373 MAIN 2 CH3 PhD Qurentto Lowpass 4 Lowpass __ Amplifier PCB No 6362 MAIN Converter Section to PCB No 6373 MAIN 2 ToT Lowpass pass Amplifier ii to PCB No 6362 MAIN Volt o o Converter Filter f Section CHS io PCB No 6373 MAIN 2 PCB N No 9259 LED1 15V PCB No 9258 LED2 IF 20mA from PCB No 6362 MAIN No 9258 LED2 from PCB No 6373 MAIN 2 AL a r a m Ge a Au i m Current to i Lowpass Amplifier to PCB No 6362 MAIN Volt o PRO Filter Section CH6 to PCB 6373 MAIN 2 No 9259 LED1 Constant from PCB No 6362 MAIN OPTION Circuit Current Circuit from PCB No 6373 MAIN 2 Figure 3 4 PCB No 2132 and 2156 Block Diagram
6. 5 18 5 7 4 Tes NO 5 18 5 4 5 ADC BUFF FOr Factory USC ONIY J uuu uuu uusha i 5 18 5 6 Vlin interim For Factory Use 5 18 55 5 19 5 9 Output of service settings 5 21 LED C libri 5 22 5 10 1 Adjustment Value Calculation Method a a 5 23 511 Factory Seting Value LablGiu uum a batis qasi 5 24 0 11 1 Position nnns anrea 0 24 0 11 2 Detector Block Adjustment 0 25 0 11 3 Temperature Adjustment Value 0 25 9 11 4 Transmitted Light LED Adjustment 5 25 5 11 5 Pressure Adjustment Value 0 25 SLG SENCE Seting u uu u 5 26 RUN AES Mode THEE 5 26 5 11 8 Reagent Vial Setting 5 26 5 11 9 LED Calibration
7. A 1 4 CA 500 Chassis ASSY 1 2 UE RA Ia Sui GR noA T Ram ro d A 1 6 gos UU M 1 8 De uei 1 10 GA 500 Cooling Section ASSY m 1 12 Table Lock eem 1 14 1 14 1 16 CA 500 1 18 CA 500 Pipette Holder ASSY uci adeo ba pa Een ndo D In Pe RE a a tota A 1 18 CA 500 Volumetric Piston A 1 20 eo Cylinder ASSY A 1 20 CA 500 Volumetric Mech Assy nnns nnn nnns A 1 22 CA 500 Operation Panel Assy 1 2 A 1 24 CA 500 Operation Panel Assy 2 2 A 1 26 CA 500 Rear Panel for Bottles esses A 1 28 CA 500 Rinse Bottle Assy A 1 30 500 Waste Bottle Assy 8 nnn A 1 30 CA 500 Accessories A 1 32 CA 5H Z Axis Position Adjustment Tool 13 A 1 32 CA 500 Tubing A FA u uu u u A 1 34 CA 500 Pressure Chamber Assy A 1 36
8. 26 IN NOP DO m 30 wegen MUR 17 No Sample Rack er 14 Ili je Pu 1 wi cie 31 Prone 18 Dar EI eects cant rc ne 29 lite cep cident S s 34 EMCE TOP 34 CA 500 Series S M Revised December 2001 g IR Replace STAT Sample 25 Replace Sample RICK L L uuu uu EO E 21 Replace Sample Rack 22 Replenish Rinse Reagent T 7 5 Sampling EITOF Position u uu u ul 15 MI emi ge 33 21 SOL MOLE Man WQ SEN SIM NON A ud 34 Standard Curve 35 Sred Data EMOT cn E Sentence Pan 29 u u ERES 19 1 Temp Sensor Error CP OSIM ETERNI 6 Temperature Error High Cooler Temperature Error Low Cooler 5 Temper
9. m 1 37 67 22 6 0 1101 9 A 1 38 CA 500 Trap Chamber Kit option 9 E A 1 39 CA 500 Recommended A 2 01 Alphabetical NOC X 3 01 PIT 4 01 CA 500 Series 5 A 1 1 Revised October 2003 ECR303G037 500 Unit Chassis 1 2 CA 500 Series S M A 1 2 Revised December 2001 8 500 UNIT CHASSIS ASSY 1 2 Description Qty per Unit Code No Drawing No 663 0202 5 1 663 0203 9 26 663 0400 9 2 663 0168 5 3 663 0174 8 4 663 0173 4 4 662 2219 8 5 228 3418 6 6 663 0179 6 7 228 3754 7 8 663 0205 6 9 663 0177 9 10 663 0176 5 11 662 8181 6 12 663 0204 2 13 amp 663 0401 2 13 324 9079 8 14 324 9075 3 15 363 2558 6 OPTION 363 2559 0 OPTION 913 1091 3 OPTION 7 365 9200 4 OPTION CA 500 Series S M REAGENT STAGE ASSY SAMPLE STAGE ASSY SAMPLE STAGE ASSY 2 IMMUNO OPERATION PANEL ASSY SAMPLE TABLE ASSY ID SAMPLE TABLE ASSY STANDARD POWER SWITCH ASSY CA 500 PHOTO SENSOR EE SX670 SAMPLE RACK SENSOR ASSY LCD LRHBJ3431A PRINTER COVER ASSY ID ASSY ID MOTOR ASSY ID WIRING CORD LIGHT SHIELD COVER ASSY LIGHT SHIELD COVER ASSY IMMUNO STAY DM1102 COVER SENSOR SHUTTER B DM1374 HOLDER NO 89 HOLDER NO 90 TTO STANDARD SCATTERING STICK SET SPACER FOR RUBBER SHOE A 1 3 gt lI ll 663
10. Code No Drawing Description Qty per Unit No 324 9083 3 1 LOCK SPRING DM1298 1 6 324 9084 7 2 SS BASE PLATE DM1361 1 6 324 9085 1 3 SS ACTIARM DM1362 1 663 0175 1 4 SAMPLE TABLE BASE ASSY 1 CA 500 Series S M A 1 38 Revised February 2004 19 TB200408 CA 500 Pressure Chamber OPTION 9 Code No In the following CA instruments the Pressure Chamber Kit has already installed CA 510 S N A1023 and thereafter CA 530 S N A1368 and thereafter CA 540 S N 2016 and thereafter 021 0011 0 365 1333 3 443 0823 8 363 5015 0 363 1597 8 443 2804 4 346 3939 1 346 3909 0 348 5082 5 348 3812 1 442 5305 4 442 5290 6 442 5475 1 461 9128 7 CA 500 Series S M Drawing No Description PRESSURE CHAMBER KIT CA 5H SUPPORT NO 247 CHAMBER NO 4 FIXING MATERIAL NO 15 STAY NO 11 NON RETURN VALVE MFP 6 V O RING P 39 O RING P 8 NITRIL SCREW HEX SOCKET BOLT M8X14 SU SCREW BINDING M3X6 SUS TUBE SILICONE 2 X 4 SR 1554 TUBE SILICONE 4MMID X 8MMOD TUBE TOALONE 3MMID X 6MMOD TRAP CHAMBER PROCEDURE A 1 39 Qty per Unit 10 10 50 100 20 10 Added May 2002 500 RECOMMENDED PARTS PART NO No PART DESCRIPTION UNIT Q TY CLASS A 663 0188 0 A 1 CATCHER ASSY 1 663 0162 3 2 COOLER ASSY 1 662 0221 9 A 3 PCB NO 6362 1 662 0287 4 A 3 PCB NO 6373 1
11. ws 2 4 10 529 94 1 sod ZAX 94 N 9d s 8LNO SNO AGS 9L 4 O V 1euojsuei AO00LOV m AA 4 1h 6NO Fh AOOLOV 3s NS d me LNO Boy MS 99JnoS JOMOd Avzoa y MS uey 2807 ONSOd Sd epoueg 6 NOILdO yun qI il YOYUMS uoaa 9 yoey yoo uogoejeg 9 49 1 aiqe ldues 491009 mer E SF Jopejeqjeuueu uopesBupoo 2 yoey U9IIMS _ JehoD duo JO IOSUBS CA 500 TUBING DIAGRAM Drawing Description 662 2207 3 662 2206 0 663 0163 7 663 0162 3 663 0200 8 663 0179 6 662 8181 6 663 0176 5 663 0177 9 663 0196 0 265 1243 1 662 8182 0 663 0201 1 265 1242 8 663 0185 9 663 0186 2 663 0190 8 265 1241 4 663 0187 6 662 2203 9 663 0160 6 662 2204 2 662 2205 6 663 0210 5 663 0169 9 663 0171 7 289 9170 6 663 0165 4 663 0191 1 663 0198 7 941 0131 3 663 0197 3 663 0209 1 662 8222 1 CA 500 Series S M THERMAL SENSOR ASSY COOLER THERMAL ASSY COOLING FAN ASSY COOLER ASSY SOLENOID ASSY SAMPLE RA
12. 23 GPU Failure dh 40 Change Sample ee ee ee ene ae ae 24 ion MM O doce 28 MTS O ESDI 28 Check Reagent Volume 38 CIO k oy ee 20 Fi O E S 38 Exist same Sample NO a a aaa ar 26 H u u uuu EE su 32 SI j 33 l t I u 32 HC Communication l il ii 32 4 HI OIL T 33 1929 1 31 AG Reception Count EMOT uuu P 32 zl TE OU M 33 HIC Transmission C unt Errer u u TUm unm 32 l ISMUCHON NOU Found IM EN 33 Insufficient Reaction Tube 38 Insufficient Reagent Holder No 16 Ilerrupt by Mechanical 36 l i Ems 29 L Light Shield CIN uu 37 NOW
13. lI gt ll 1 I I I I I I I lI I I lI lI A 1 5 A 1 33 A 1 7 A 1 5 A 1 5 A 1 35 A 1 36 A 1 31 A 1 31 A 1 31 A 1 31 A 1 31 A 1 31 A 1 19 A 1 5 A 1 33 A 1 17 A 1 17 A 1 17 A 1 19 A 1 31 A 1 31 A 1 31 A 1 31 A 1 31 A 1 31 A 1 31 A 1 31 A 1 11 A 1 5 A 1 39 A 1 36 A 1 11 A 1 35 A 1 11 A 1 35 A 1 5 A 1 29 A 1 35 A 1 13 A 1 35 A 1 13 A 1 13 A 1 35 A 1 9 A 1 13 A 1 3 A 1 21 A 1 21 A 1 11 A 1 11 A 1 9 A 1 11 A 1 9 A 1 11 A 1 9 Revised February 2004 TB200408 5 13 15 13 15 33 35 33 35 16 26 36 4 5 14 15 8 amp 26 6 85 M N OQ N N W N N gt ana 3 Qm 4 1 6 488 1 8 4 amp ALPHABETICAL INDEX ES EST SS AJLA a CA 500 Series S M PARTS DESCRIPTION DETECTOR BLOCK D DIMER DETECTOR BLOCK STANDARD DETECTOR BLOCK STANDARD DETECTOR THERMAL ASSY DETECTOR THERMAL ASSY DRIVE ARM ASSY EMERGENCY STOP SW ASSY EMERGENCY STOP SW ASSY FILTER ASSY FOR RINSE BOTTLE FILTER ASSY FOR RINSE BOTTLE FIXING MATERIAL NO 15 FIXING MATERIAL NO 15 FIXING SCREW TL 233 FUSE 125V6A UL TSC 6A N 1 FUSE 250V3 15A NO 19195 EUROP FUSE 250V6 3A 4 6 1 FUSE HOLDER CAP 031 1663 EUROP FUSE HOLDER CAP 031 1666 N AME FUSE THERMAL 125V5A TYPE210 HEAT SINK DM1113 HEATER ASSY HEATER ASSY HINGE R 45 N GREASE TOA HOLDER NO
14. S Ready IP YSME Replace Rack YES Adjust Mecha Position Adjust Data Print Detector Gain Temp Control Adjust of Pump Trans Light Calib Return Figure 5 3 1 Adjust Menu Screen 5 3 1 Printing Adjustment Data From Adjust menu press Adjust Data Print key The adjustment setting values are printed to the built in printer 06 17 1999 11 22 Position PULSE blood 1 X 1839 06 17 1999 11 22 Y 2265 DETECT Z 1246 OFFSET GAIN blood10 X 4061 1 HIGH 128 128 Y 2265 LOW 139 128 Z 1246 PT 139 128 blood stat X 1485 2 HIGH 114 159 Y 2265 LOW 134 232 Z 1246 PT 134 235 warm3 X 1469 Y 80 06 17 1999 11 22 Z 356 TEMP warm4 X 605 COOLER 128 Y 944 Main 128 Z 356 Sub 128 comp X 722 128 Y 512 Main 128 Z 369 Sub 128 shake X 137 PIPETTE 128 Y 512 Main 128 Z 29 Sub 128 dust X 154 ROOM 128 Y 203 Main 128 Z 376 Sub 128 Figure 5 3 2 Example of Setting Data Print Out CA 500 Series S M 5 4 Revised December 2001 g 54 INITIALIZE Use to initialize the settings stored data etc and to check memory 1 From the Main menu press Special Operate gt Service gt Initial keys S Ready IP Replace Rack YES Initial Init Stored Data Verify Control Init QC Data Init Settings 1 Init Entire Memory Init Settings 2 Return
15. SP RESUME 2 2 2 2 1 ege sq T 2 2 2 2 2 oi CT M 2 2 PRES Ge 0 NT 2 4 2 3 1 2 4 2 3 2 2 4 24 DETECTOR BLC OCK eee ee 2 5 2 4 1 Gu 2 5 2 4 2 0 UU LLULLU L LI 2 5 24 3 PRS 9 2 2 5 29 REAGENT COOLING UNIT uuu esas cns 2 6 2 5 1 eu eee 2 6 2 5 2 ejerce perse gc FUNCIONS NN 2 6 28 07 AS qas 2 6 20 VOLUME TRIC ONEE 2 7 2 6 1 Ili 2 7 2 6 2 FUNCOMS ufus sime 2 7 203 MER 2 7 2 X Y DRIVE UNIT X AXIS MOTOR ASSEMBLY DRIVE AXIS ARM ASSEMBLY 2 8 2 7 1 Sa E 2 8 2 7 2 Specilicalions FuncCto onSs uuu UL aa 2 8 Ala 2 8 2 8 Z AXIS DRIVE UNIT Z AXIS BASE 2 9 2 8 1 2 9 2 8 2
16. Figure 5 4 3 Data Check Screen 5 4 7 Contents stored in BBRAM 1 Stored data 2 data 3 Flag for error message Turned Off During Operation Syringe operation cycle counts Test counts 4 Group selection number Rinse Wait time Clean Sample Probe Catcher transfer test cycle counts Catcher transfer test error cycle counts Storing dummy range CA 500 Series S M 5 7 Revised December 2001 g 5 4 8 Contents stored EEPROM 1 Standard Curve data Units for calculation parameters 2 User settings Auto Val Out Mark Limits Replic Limits Report Limits Set Test Name Set Reagent Name Test Protocol Set Replication Test Group Reagent Holder Alarm Settings Conversation Host Computer Barcode Scanner Date Format Password 3 Manufacturer settings Service settings Analysis Parameters Confirmation Mode Reagent Vial settings 4 Others Detector block sensitivity adjustment value Temperature control value Touch panel position adjustment calibration value fixed XYZ Axes position adjustment value Barcode DC motor position adjustment value fixed Pressure adjustment Main unit temperature Conversion value Sensor temperature Conversion value 5 Others Barcode scanner types Ensuring the dummy range 5 4 9 Items needing backup when initializing The following items are required the backup printing out when replacing PCB No 6362 1 EEPROM All data excluding fixed data 2 BBRAM Group selection number
17. e 5 V Power Source for Printer 5 V voltage regulator 1A 1 5 Power Source for Stirrer Motor Variable A Drivers e Stepper Motor Driver for X Axis STK6713B Stepper Motor Driver for Y Z Syringe STK6712B ID Unit Motor TA8415 TD62308 Solenoid Valve TD62308 Probe Heater Detector Block Heater Peltier Cooler Power MOSFET Sampler Table Lock Mixing Motor Transistor with resistor Vacuum Pressure Pump AC Photo coupler TLP3503 CA 500 Series S M 3 11 Revised December 2001 3 6 2 Block Diagram from Transformer from SW Regulator from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No from PCB No CA 500 Series S M AC16 5V _ 4 Constant gt 15 ARE Rectification _ GND to PCB No 6362 MAIN to PCB No 6373 MAIN 2 5 24 5V RETURN Constant 12 pP 24 Voltage 5 12 RETURN to PCB No 6350 PRCN1 to PCB No 6373 MAIN 2 7 7 24 RETURN Sy 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2 6362 MAIN 6373 MAIN 2
18. 14 XYZ Driving Function Pipette and sample catcher mechanism on the head unit Z axis is driven by the XY axis mechanism to dispense sample and reagent and transfer and discard the reaction tubes 1 XY axis Mechanism Linear Slider driven by stepper motor 2 Z axis Mechanism Pipette and sample tube catcher are driven by one motor Mixing Function After dispensing the reagent the reaction tube is vibrated and mixed by the miniature motor Sample Data Storage Function 1 Contents of Data i Measurement data ii Setting values iii Quality control data iv Date year month day hour minute 2 Memory Capacity i Data of 300 samples maximum 1500 tests 300 samples X 5 parameters The analysis print data is not stored once the power is OFF As for the reaction curve the latest 600 tests are stored ii Quality control data 12 kinds X 7 parameters X 180 plots CA 510 to CA 540 6 kinds X 14 parameters X 180 plots To the Quality Control file the parameters of dilution magnification such as Fbg Fbg 00 DDPI SFD and PFD are also included CA 550 and CA 560 only Display and Input Function 1 Display Type Graphic panel display touch panel using a 3 2 X 4 inch liquid crystal display white and black back light 2 Displayed Data i Date ii Measurement condition Analysis status Results iii Stored sample Stored sample list Date Time Sample ID number Parameter name Measured data
19. 5 26 5 11 10 Analysis Protocol u uu uuu uuu nne nennen nnne nennen nsns 5 27 5 11 11 Customer Setting 5 29 5 11 12 Standard Curve 5 32 5 11 13 Quality Control Setting Valu usi eue sant ce pc es 5 33 5 11 14 Analysis Parameter Default Setting Value r 5 34 5 12 Settings of CA 500 with 800nm detector 17 5 36 CA 500 Series S M Revised October 2003 ECR303G037 SECTION 5 SERVICE PROGRAM 5 1 SERVICE MODE 5 1 1 Starting and quitting the Service Mode To start the service mode 1 Press ID No Entry key on the Ready screen then the ID No entry screen will be displayed 2 Press 9 0 Enter and Quit keys To quit the service mode 1 Press ID No Entry key the Ready screen then the ID No entry screen will be displayed 2 Press C 0 Enter and Quit keys Light Shield Open error is skipped during entering Service Mode When entered Service mode Special Calibration key is added in Analysis settings screen However do not change parameters in Special Calibration screen New main board PCB 6373 only 5 1 2 Menu Structure Special Operate CA 500 Series S M 5 1 Revised May 2003 ECR 303C012 5 2 SER
20. Short circuit the pin 19 and pin 17 of the relay connector on the rail If this allows monitoring the detection of home position the sensor inside the sample rack drawer or wiring cord wiring cord for ID barcode reader is faulty 5 Short circuit the pin 13 and pin 11 of CN111 on PCB No 6362 If this allows monitoring the wiring cord wiring cord with spiral is faulty otherwise PCB No 6362 is faulty Check whether the drive mechanism shaft is free from flaws Check whether the slide of shaft bushing is smooth or not If the motor does not operate or unstable even when the shaft is free from problems any of ID motor assembly wiring cord wiring cord for ID barcode reader wiring cord wiring cord with spiral or PCB No 4086 is faulty Q NI OD 6 6 9 Load New Sample Monitor Timing When the analysis 15 re started after interrupted to load new sample Monitor Method Sample rack sensor is monitored CA 500 s Action Warning 1 Probable Cause 1 New rack is not loaded when the analysis is re started after adding new order 2 Confirmation by the operator 1 Check sample rack 2 Check sample table 3 Confirmation by Service Engineer 1 Check the sample rack sensor CA 500 Series S M 6 26 Revised December 2001 g 6 7 ANALYSIS ERRORS 6 7 1 Analysis Error Monitor Timing When measuring analyzing Monitor Method Coagulation Error code Status Actio Temp Error sa
21. Voltage Drop Monitor Circuit U507 508 When the Power Source of 24 V decreases to approximately 20 7 V and the PS of 15 V to 13 8 V respectively this circuit can detect the voltage decrease by interrupt signal and latch RESET Backed up Switching Circuit U210 U804 This circuit monitors the digital 5 V source and if it becomes less than approximately 4 75 V RESET signal is generated and the protection for writing of the backed up RAM and real time clock is performed at the same time Also the DC 5 V is switched by the battery power source This circuit generates L when the voltage becomes less than 4 V to avoid unstable RESET signal EEPROM WORK RAM B RAM EEPROM U905 WORK U901 904 B B RAM U801 802 EEPROM is 8KB WORK RAM is 512 KB with SRAM and B B RAM Battery Backed up RAM is 256 KB with SRAM Real Time Clock U803 This is battery backed up as the calendar clock PRCN1 Interface U301 312 313 This circuit performs the interface with the control board PCB No 6350 PRCN1 for Built In Printer It uses a port U301 and buffers U312 313 LCD Interface U701 702 704 This circuit performs the LCD display by using the LCDC LCD Controller U701 It writes the display dot image on the 256Kbit VRAM U705 by the LCDC and displays on the LCD via the buffer U702 based on the image data 8 MHz frequency is supplied as the internal clock and 2 MHz is supplied for LCD display timing The nega
22. 3 Confirmation by Service Engineer 1 The PCB No 6362 or backup battery is faulty CA 500 Series S M 6 29 Revised December 2001 8 6 9 EXTERNAL DEVICE ERRORS 6 9 1 No Paper Monitor Timing At time of printing Monitor Method Monitoring PE signal from Printer CA 500 s Action Warning and no printing 1 Probable Cause 1 No printer paper Failure of Printer Failure of PCB No 9265 Failure of wiring cord for printer relaying Failure of PCB No 6350 Failure of wiring cord for printer signal W 2 Confirmation by the operator 1 Place printer paper correctly 3 Confirmation by Service Engineer Suspect Part Test Points Expected Value Printer CN5 PCB No 9265 pin 3 and pin 1 1 2 V 0 2 V CN5 PCB No 9265 pin 3 and pin 2 5 gt 0 15 9265 PCB No 9265 14 and 12 5 when paper is set Wiring Cord for printer relaying CA 500 Series S M 6 30 Revised December 2001 g 6 9 2 Printer Error Monitor Timing At time of printing Monitor Method Monitoring head up signal of Printer CA 500 s Action Warning and no printing 1 Probable Cause The head up lever is not set down Failure of Printer Failure of PCB No 9265 Failure of wiring cord for printer relaying Failure of PCB No 6350 Q N 2 Confirmation by the operator 1 Place printer paper correctly 3 Confirmation by Service Eng
23. B 8 Adjust LCD Contrast With the printer cover removed LCD contrast can be adjusted using the contrast adjust dial located on the left of the printer Turn the dial up for darker shade and turn it down for lighter shade Contrast Adjust Dial NI Figure B 14 Adjusting the LCD Contrast CA 500 Series S M B 10 Revised December 2001 8 B 9 Replenish Rinse Solution 1 Press Special Menu key on the Root Menu screen The contents of the Root Menu will changeover 2 Press Special Operate key the Root Menu screen The Special Operation Menu screen will appear Ready HC IP SYSMEX Replace Rack YES Special Operation Hinse amp Prepare System Tests Cycle Counter Figure B 15 Special Operation Menu Screen 3 Press Rinse amp Prepare key on the Special Operation Menu screen The Supply Liquid Confirmation screen will display the message Water supply HC IP Sysmex Replace Rack YES DEMNM Supply Liquid Water supply Cancel Figure B 16 Supply Liquid Confirmation Screen 4 Press Set key or Cancel key on the Supply Liquid Confirmation screen Set key Executes water supply Cancel Cancels water supply and returns the screen to the Root Menu CA 500 Series S M B 11 Revised December 2001 5 Water supply begins When Set key is pressed water supply will begin and the message Water supply running will appear To stop water supply while
24. Figure 5 4 1 Initial Menu Screen 2 Press a desired menu key then the confirmation screen will appear Ready IP oysmex Replace Rack YES Initialize Set Cancel Figure 5 4 2 Initializing Confirmation Screen 3 Press the appropriate key Set To start initializing Cancel To cancel initializing 5 4 1 Initializing Stored Data Initialize all stored data 300 samples and all coagulation curve data 600 tests 1 Press Int Stored Data key then the confirmation screen will appear 2 Press the appropriate key Set To start stored data initializing When completing the Initial screen will appear Cancel To cancel stored data initializing and return to the Initial screen CA 500 Series S M 5 5 Revised December 2001 g 5 4 2 Initializing QC Data Initialize all QC data 7 items 12 files 1 Press Int QC Data key then the confirmation screen will appear 2 Press the appropriate key Set To start QC data initializing When completing the Initial screen will return Cancel To cancel QC data initializing and return to the Initial screen 5 4 3 Initializing User Settings 1 Press Int Settings 1 key then the confirmation screen with Initialize Standard Curve Settings message will appear When selecting this key following customer setting items will be initialized in order Setting value Auto Val Ou
25. S O O A 1 11 1 9 1 11 1 11 1 35 1 7 1 27 1 35 1 31 1 31 1 39 1 36 1 33 1 5 1 5 1 5 1 5 1 5 1 11 1 13 1 11 1 35 1 7 1 3 1 3 1 5 1 3 1 35 1 3 1 35 1 3 1 35 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 25 1 25 1 3 1 25 1 31 1 31 1 31 1 31 1 3 1 3 1 38 1 5 1 35 1 19 1 35 1 21 1 88 7 6 5 21 7 OPTION OPTION 15 10 9 11 8 12 7 5 15 24 34 25 19 11 Revised February 2004 TB200408 ALPHABETICAL INDEX AA EIN S S CA 500 Series S M PARTS DESCRIPTION NIPPLE NO 123 NON RETURN VALVE MFP 6 V NON RETURN VALVE MFP 6 V NON RETURN VALVE MFP 6 V OPERATION PANEL ASSY OPERATION PANEL ASSY OPERATION PANEL ASSY OPERATION PANEL BASE ASSY OPERATOR S MANUAL CA 500 OPERATORS MANUAL CA 500 2 O RING NO 16 O RING P 8 NITRIL O RING P 39 O RING P 39 O RING P 8 NITRIL O RING S 3 SLICONE PANEL L DM0931 PANEL R DM0932 PAPER THERMAL F1 2 5 BOX PCB NO 6350 WITH ROM PCB NO 6350 WITH ROM FOR CA PCB NO 6375 ASSY PCB NO 2132 2 CIRCUITS PCB NO 2132 3 CIRCUITS PCB NO 2132 STANDARD PCB NO 2134 PCB NO 2156 2 CIRCUITS CLOT PCB NO 2156 3 CIRCUITS AT3 DD PCB NO 2156 4 CIRCUITS DD 800NM PCB NO 2156 5 CIRCUITS D
26. and gt keys to adjust the pipette tip to become the center of the rinse cup Press Z TEST key to descent the pipette The pipette detects the distilled water and stops Use 1 lt and gt keys to adjust the pipette tip to become the center of the probe rinse cup outside Press Z TEST key again to ascend and descend the pipette Verify that the pipette is placed at the center of the sample cup Figure 4 3 13 Probe Rinse Cup Outside Press XY ORG key to return the pipette head to the home position CA 500 Series S M 4 19 Revised December 2001 2 Z Adjustment 1 Select Special Operate gt Rinse amp Prepare from the Menu and supply rinse reagent into probe rinse cup outside 2 Move the pipette to the adjustment position by using XY TEST key 3 Press Z ADJUST key to descent the pipette 4 The pipette detects the liquid surface of the probe rinse cup and stops The following screen will appear by pressing Enter Pulses key Press X Y Z key twice to move cursor to Z Enter 25 added pulses to present Z pulses and press Enter and then Quit key The value will be stored in the memory when Mecha Position adjustment is completed Ready Replace Rack YESI Mecha Position Probe Crash Senser Liquid Senser Old New Now lube catch X 1785 1780 0 Y 2316 2316 0 7 8 Z 1221 1221 Pipette Bottom 10 Wash O Figure 4 3 14 Enter Pulses Screen
27. 24 24 240 gt 12 AC100V 1 Constant Current Buffer gt Drive IC STK6713B Constant Current Buffer Drive IC STK6712B Z Constant Buff 4j Current uer Drive IC STK6712B Syringe Constant Current Buffer Drive IC STK6712B ID Unit Motor EN Stepper Motor Constant CW CCW pulse Current CLK ganerator Drive IC TA8415 TD62308 Pressure Pump AC Power AC100V 2 ON OFF Photo Coupler Vacuum Pump AC Power AC100V 2 ON OFF Photo Coupler AC100V 1 Figure 3 8 b PCB No 4086 Block Diagram Continued Circuit Explanation 1 Stepper Motor Control Circuit for X Y Z Drive mechanism and Syringe This stepper motor operates by the two phase constant current drive 2 Motor Drive Circuit for ID Unit to Stepper motor for X Axis to Stepper motor for Y Axis to Stepper motor for Z Axis to Stepper motor for Syringe to Stepper motor for ID Unit to Pressure Pump to Vacuum Pump 1062308 drives the stepper motor by the four phase pulse generated at TA8415 from the CLK signal generated on PCB No 6362 MAIN or PCB No 6373 Main 2 This stepper motor is operated by the two phase voltage drive Vacuum Pressure Pump Driver Circuit 3 This circuit turns the vacuum and pressure pumps ON OFF at TLP3503 by the control
28. CA 500 Series S M 2 11 Revised February 2004 TB200408 SECTION 3 ELECTRONICS To Cover 3 1 3 2 3 3 3 4 3 5 3 6 3 7 3 8 3 9 3 10 3 11 3 12 3 13 3 14 3 15 o u E E anus busana m 3 1 Block Diagram and Power Source T rra asar UEM DAE 3 2 PCB No 2132 PD Photo Diode Pre Amplifier LED Relay 3 6 PCB No 2156 PD2 Photo Diode Pre Amplifier LED Relay 3 6 PCB No 2133 THERMO Thermister 3 8 PCB No 2134 Y Z RELAY Liquid Surface Sensor Probe Crash Y Axis Home Position Sensor Z Axis Relay cccccceecceceeeeeeeeeeceaeeceeseeeeeseeeeeeseeeeeseeeeseaeeesaeeeeeseeeeeeseees 3 8 PCB No 2157 Y Z RELAY2 Liquid Surface Sensor Probe Crash Y Axis Home Position Sensor Z Axis 3 8 PCB No 4086 PS Power Source Motor Driver a a 3 11 PCB No 6350 PRCN 1 Printer Control Board a arar rrssrrssssrssssasaa 3 15 PCB 6375 PRCN 3 Printer Control 3 15 PCB No 6362 MAIN CPU
29. CA 500 Series S M 3 6 Revised December 2001 g 3 3 3 Circuit Explanation 1 Pre Amplifier Circuit 1 Current Voltage Converter U1 2 4 The photo diode receives scattered light and generates small electric current This circuit converts this current into a voltage 2 Low pass Filter R6 C5 R15 C12 R25 C20 Low pass filter reduce the noise 3 Amplifier U3 The channels CH1 CH4 are the direct current amplifier with a gain of 11 times The channel CH5 and CH6 are the direct current amplifier with a gain of 1 time 4 Constant Current Circuit for CH6 U3C U5 Q1 PC1 The shunt regulator U5 releases reference voltage and releases the constant current circuit by comparing the voltage released from U3 to R32 PC1 controls isolated LED electricity ON OFF signal from MAIN PCB No 6362 or MAIN 2 PCB No 6373 and Q1 turns on constant current by ON OFF R23 R26 bleeds only to turn LED for CH6 3 3 4 Setting and Adjustment Setting and adjustments are not necessary 3 3 5 LED and Test Point There is no LED and Test Points 3 3 6 Assembly Drawing 9703 pm CO C a Figure 3 5 PCB No 2132 Assembly Drawing CA 500 Series S M 3 7 Revised December 2001 3 4 2133 Thermister 3 4 1 Function This board is used to mount the thermister Centigrade temperature sensor IC LM35DZ is used for the thermister 3 4 2 Setting and Adjustment Setting and adj
30. PCB 2157 X RELAY _ LEE PR RELAY2 Y Z RELAY Volumetric Operation Panel Surface Sensor Syringe Motor Syringe Motor Probe Crash 5 1 Y Axis Home Pos Sensor X Axis Home Syringe Home Y Axis Relay Pos Sensor Sensor X Axis Drive Motor AXIS s Crash Switch Printer Control Board Vacuum Pump PCB No 9264 Z Axis Z RELAY Drive Motor Z Axis Home Pos Sensor Sample Pipette T i jones 5 gabe Mixing Motor Program Memory Reagent Cooler Unit PCB No 6373 MAIN Thermister Cooling Fan PCB No 4086 CPU Rinse Motor Control Bottle Peltier Cooler Power Supply Temp Control Motor Drive A D Waste Sampler Bottle Sample Rack Sensor ID Unit Drive Motor 10 Unit RS232C Option Serial Port ID Unit Home Pos Sensor Table Lock Figure 3 2b CA 500 Electric Block Diagram 2 CA 500 Series S M 3 3 Revised December 2001 3 2 2 Power Supply System CA 500 Power Supply System is composed of the Power Transformer Switching Regulators and PCB No 4086 as shown in the following figure Respective voltages indicated with balloon numbers are explained in the descriptions DC12V D PCB 4086 Switching Regulator PS BOARD x E LCA150S 24 1 LCA1505 12
31. Place the sample rack drawer properly Remove any foreign matters 3 Confirmation By Service Engineer 1 2 3 4 Check the dirt on table rock mechanism and or it is free from foreign matters Check whether the light shield is damaged or not on the sample rack drawer rear side If the signal on the pin 2 and pin 3 of the relay connector for solenoid assembly does not change even photo interrupter is shaded by the light shield the solenoid valve assembly or sensor is faulty If the above step 3 does not solve the trouble short circuit the pin 5 and pin 6 of CN112 on PCB No 6362 If this solves the trouble the wiring cord wiring cord from CN19 on PCB No 4086 is faulty If not the PCB No 6362 is faulty CA 500 Series S M 6 22 Revised December 2001 g 6 6 4 Barcode Scanner Driver Error Monitor Timing When sensing barcode home position Monitor Method Photo interrupter is shaded by the light shield to drive mechanism CA 500 s Action Warning is displayed and no analysis is performed 1 Probable Cause 1 Barcode drive mechanism is obstructed Loosened pulley of motor 3 Failure of BCR motor assembly 4 Defective light shield 5 Failure of sensor 6 Flaws on shaft 7 Failure of bushing 8 Failure of wiring cord wiring cord with spiral 9 Failure of PCB No 6362 10 Failure of PCB No 4086 2 Confirmation by the operator 1 Remove any foreign matters of the barcode drive mechanism 3 Confirmation by Service
32. The delta OD after compensation a x Detected delta OD b Use of VlinIntegral Algorithm Dimension of polynomial approximate expression The start time for analysis The end time for analysis The judgement value of polynomial approximate expression result Width to search variable analysis starting time Use of variable analysis starting time The modulus for variable analysis starting time calculation The modulus for variable analysis starting time calculation The modulus for variable analysis starting time calculation The modulus for variable analysis starting time calculation The modulus for linearity range The mixing time for sample The mixing time for reagent The slant of calibration The segment of calibration The parameter for dilute ratio of standard curve analysis ON accuracy equal to the CA 1500 OFF conventional accuracy A D limit to detect low transmitted light intensity A D limit to detect high transmitted light intensity Coefficient of delta OD compensation Offset of delta OD compensation The delta OD after compensation a x Detected delta OD b The start time for Prozone check a1 The end time for Prozone check a1 The start time for Prozone check a2 The end time for Prozone check a2 A parameter for Prozone check a1 A parameter for Prozone check A parameter for Prozone check Use of VlinIntegral Algorithm Dimension of polynomial approximate expression The start time for analysis T
33. coagulation is drastic blood collecting method etc for any errors Fbg Range Over and make comprehensive judgment Chromogenic Immunoassy Emorcode Acion Trans Light Low Trans Light High No Linearity Reaction Curve Error opposite direction Range Over Immunoassy only ERRORO528 Polynomial adjustment could not Check the setting reagent and reanalyze No Polynomial be performed when using Adjustment Vlinlntegral mode only CA 500 Series S M 6 27 Revised December 2001 g 1 Confirmation by Service Engineer Adjustment of detector block Confirmation of SV function Confirmation of dispensing positions Checking the tube between the syringe and probe for breakage pin holes contamination or bubbles Check probes for contamination clogging etc Check mixing status no bubbles Check rinse solution amount and pressure Confirm plasma dispensing position in a reaction tube O 6 7 2 Check Reagent Expiry Monitor Timing When starting analysis Monitor Method Monitor standard curve reagent information and current date RTC by the software CA 500 s Action Warning is displayed 1 Probable Cause 1 Failure to preset reagent expiry date or wrong setting 2 Confirmation by the operator 1 Preset the expiry date properly in standard curve and reagent information settings 3 Confirmation by Service Engineer The same as above 6 7 3 Check Co
34. oensor For drive unit home position transmission type 1 unit 2 7 3 Assembly Diagram Y idler Y Belt X Belt Linear Slider d Y Motor X Center Shutter E 4 Y Belt o Y Motor CA 500 Series S M 2 8 Revised December 2001 8 2 8 Z AXIS DRIVE UNIT Z AXIS BASE ASSEMBLY 2 8 1 Outline To use the sample probe for aspiration or draining and to move reaction tubes this unit grips the catcher and drives it in Z direction The Z axis base assembly incorporates a mechanism for mixing plasma and reagent in reaction tubes 2 8 2 Specifications Functions 1 Z Direction System Drive Source Unipolar type stepping motor 1 2 phase excitation constant current drive Drive transmission Timing belt type Resolving power Approx 0 08 mm step Drive speed Approx 3100 pps at high speed in trapezoidal control oensor For drive unit home position transmission type 1 unit 2 Stirring Function Power source DC motor Driving voltage 1 05 V 3 Reaction tube Presence Detection Sensor Detects presence of reaction tubes modulation reflection type 1 unit 4 Sample Probe Shape Material ID 0 50 mm OD 0 85 mm 5 5316 Heater Sensor Glass chip thermistor Overheat protection Thermal fuse 76 C 2 8 3 Assembly Diagram 22 Slider Base lt gt C Subpiate C Spring Catch Rubber Harness Hold Drive Arm Harness Hold Tube Sensor Light Shield Plate xs p Tube Sensor Light Shield Plat
35. 6 Theunit temperature is automatically changed by changing the Sub value to be controlled at the target temperature of each unit 7 Press Enter key and then Quit key to complete number input 8 Press Clear key returns the cursor positioned value before it is changed which is stored in EEPROM 9 lt will be stored the memory by pressing FIX key when exiting the Temp Control screen CA 500 Series S M 4 31 Revised December 2001 45 ELECTRICAL ADJUSTMENT 4 5 1 PCB No 6362 MAIN CPU I O Motor Control Temperature Control A D PCB No 6373 MAIN 2 CPU I O Motor Control Temperature Control A D 4 5 1 1 Setting and Adjustments 1 Switch Setting 1 SW202 Table 4 5 1 Dip Switch Setting on PCB No 6362 Language Setting Bit 1 Bit 2 OFF Japanese OFF English ON Germany ON French OFF Italian OFF opanish English for U K Not used Chromogenic Unit Chromogenic Unit is used Chromogenic Unit is not used Cooler Unit Assembly Cooler Unit is not used Cooler Unit is used B B RAM Clear Setting ON B B RAM Clear at power ON OFF Normal Setting 7 EEPROM Clear Setting EEPROM Clear Normal Setting 2 J501 Used for the Gain adjustment for the pressure sensor of the pressure pump Used usually with inserting the jumper pin between 1 and C Pressure Adjustment VR502 is to adjust OFFSET VR501 is to adjust GAIN however it is adjusted and fixed at shipment Refer to Sectio
36. Liquid Serface Sensor P E E Sysmex Tube 2 O SERI Detection IM CJ y Rack Detection Sensor i AL Barcode Reader i Home Position Sensor Figure 6 1 Sensor Positions 6 1 PRESSURE ERRORS 6 1 1 Pressure Pump Error Monitor Timing At time of each analysis start and on rinse start just before opening SV Monitor Method Monitoring 225 g cm 10 by the comparator CA 500 s Action Emergency stop 1 Probable Cause 1 gt G N The rinse bottle is not connected The cap of rinse bottle is removed SV failure Pressure pump failure Perforations pinhole in the hydraulic line Pressure sensor failure Sensor circuit failure Drive circuit failure 2 Confirmation by the Operator 1 2 Properly connect the tube Securely tighten the bottle cap 3 Confirmation by the Service Engineer 1 2 When SV is faulty rinse solution keeps flowing out from sample probe or rinse cup Replace faulty SV When the hydraulic line has no failure the pressure pump or related electronic circuit has a trouble If replacement of the pressure pump allows the pressure adjustment the pressure pump
37. PCc second Calculated Parameters a Activation Percent 90 9 Batroxithonbin BXT second 10 LA1 LA2 second Options 11 Anti thrombin 96 12 a2 Anti plasmin APL 96 13 Anti plasminogen Plg 90 14 Protein C PC 96 15 Heparin Hep 90 International Unit IU mL 16 FDP SFDP ug mL 17 Plasma FDP PFDP ug mL 18 D Dimer DPI DD g mL ug mL 2 Measurement Ranges 1 Fbg Measuring is possible from 25 mg dL to 1000 mg dL of the fibrinogen concentration In case of 450 mg dL or above measurement is performed with automatic re dilution in high Fbg concentration mode and in case of 50 mg dL or less in low Fbg concentration mode In CA 550 and CA 560 measurement for 900 mg dL or above is performed in high Fbg concentration mode and for 100 mg dL or less in low Fbg concentration mode 2 D Dimer CA 550 and CA 560 only With applicable reagents measuring is possible from 50 to 9999 u gL However the concentration of 2000 or above is measureed in 8 hold dilution mode D Dimer 3 Serum FDP CA 550 and CA 560 only With applicable reagents measuring is possible from 2 5 to 320 ug mL However the concentration of 40 ug mL or above is measureed in 8 hold dilution mode PFC 4 Plasma FDP CA 550 and CA 560 only With applicable reagents measuring is possible from 2 5 to 480 ug mL However in the concentration of 60 ug mL or above measurement is performed in 8
38. Press OK key to save the new adjustment value and return to Calibration screen Take out the calibrator for the calibration and set the former reagent 4 9 2 Revised May 2003 ECR 303 012 4 3 Mechanical System Adjustment 4 3 1 Required Tools for Adjustment Sample Cup small Reaction Tube Collection Tube 15 mm diameter Dade 1 mL Reagent Bottle Push Vial Bottle Water distilled water Dispensing Pipette 50 and 60 CA 5H Z axis Position Adjustment Tool PM 031 0171 4 lt lt 4 3 2 How to Enter the Mechanical System Position Adjustment Mode 1 Start the service mode by pressing ID No Entry 9 0 Enter and Quit 2 The screen changes from Main Menu to Mecha Position by pressing keys of Special Operate gt Service Adjust Mecha Position Select the unit to be adjusted on this screen and perform the position adjustment CA 500 Series S M 4 10 Revised May 2003 ECR 303C012 4 3 3 The Mechanical System Adjustment Screen 18 2 3 4 19 Duden place CHANG Probe Crash Senser Liquid Sense 4 760 Tube catch Y 2320 2316 Z 1220 1221 o 7 TEST iq sen Pipette Bottom 1246 5 1 15 17 Figure 4 3 1 Mecha Position Screen 1 Indicating the title of displayed screen 2 Display setting values which indic
39. Rinsing time CA 500 Series S M 5 8 Revised December 2001 g 55 TEST MENU 1 From the Main menu press Special Operate Service Test Menu keys S Ready IP TN Replace Rack YES Test Menu Drain Liquid Catcher Test Dispense Volume Full Power Reagent Temp Tube Trans Test Return Figure 5 5 1 Test Menu Screen 2 Press a desired key to start test 3 Press Return key to return to the service menu screen 5 5 1 Drain Liquid For shipment draining the liquid from the instrument use two operations 1 Press Special Operate Service Test Menu Drain Liquid keys to start then the following screen will be displayed Ready IP Replace Rack YES Drain Liquid oysmex Water Drain Process 1 Set Cancel Figure 5 5 2 Drain Liquid Confirmation Screen Water Drain Process 1 This process discards the liquid in the Rinsing bottle then select the appropriate key CAUTION Be careful when opening the rinsing bottle as it is pressurized CA 500 Series S M 5 9 Revised December 2001 g 2 Select the appropriate key Set Drains water in the pipette or tubes into the waste bottle through rinsing cup approx 1 minute When completing the confirmation screen of Water Drain Process 2 will be displayed Cancel Returns to the Service Menu screen without performing the water drain se
40. T or 4 key Low Gain is fixed and cannot be changed 4 Press Auto Adjust key to start the automatic offset adjustment and when the adjustment is completed the alarm sounds 5 Execute Steps 1 to 4 for channel 6 2 Gain adjustment Dynamic Range adjustment 1 Dispense 200 uL of distilled water or buffer OV 30 into a reaction tube in advance set it into the transmitted light detector well channel 5 and heat it up for approximately 10 minutes 2 Close the light shield cover 3 Select CH5 by using Channel Change key and select Gain position by pressing 1 or J key Low Gain is fixed and cannot be changed 4 Press Auto Adjust key to start the gain adjustment and when the adjustment is completed the alarm sounds 5 Open the light shield cover rotate the reaction tube set in the channel 5 detector well and verify that the indicated A D value does not exceed 4 000 At this time avoid the external light as much as possible the A D value exceeds 4 000 set the reaction tube at the position where the indicated A D value is the biggest and press Auto Adjust key again to start the adjustment 6 Execute Steps 1 to 5 for channel 6 CA 500 Series S M 4 8 Revised December 2001 4 2 5 Exit Adjustment 1 When the adjustment is completed press Return key 2 FIX Cancel the set value and continue the adjustment 1 When the adjusted value is settled and the adjustment is completed press FIX Stor
41. The parameter for dilute ratio of standard curve analysis ON accuracy equal to the CA 1500 OFF conventional accuracy 5 14 Revised December 2001 8 Chromogenic Method Low Light Error Limit High Light Error Limit Reagent Correlation a Reagent Correlation b VlinIntegral Algorithm Polynomial Dimension Start Time End Time Integral Area auc Minimum Search Window Variable Start Time Search Width for Preevaluation Upper max Evaluation Offset Upper Preevaluation Rate Lower Preevaluation Rate Min Regression Time Mixing Time for Sample Mixing Time for Reagent Calibration a Calibration b High Accurate Dilute ratio lt Immunoassy Method Low Light Error Limit High Light Error Limit Reagent Correlation a Reagent Correlation b Start Time a1 Stop Time a1 Start Time a2 Stop Time a2 Cut Off Rate Offset VlinIntegral Algorithm Polynomial Dimension Start Time End Time Integral Area auc Minimum Search Window Variable Start Time Search Width for Preevaluation Upper max Evaluation Offset Upper Preevaluation Rate Lower Preevaluation Rate Min Regression Time Mixing Time for Sample Mixing Time for Reagent Calibration a Calibration b High Accurate Dilute ratio Print Key A D limit to detect low transmitted light intensity A D limit to detect high transmitted light intensity Coefficient of delta OD compensation Offset of delta OD compensation
42. a 1 Be 2 Remove Shipping 3 B4 Atach Trap Gliamkpbru B 5 5 Connect Rinse Bottle and Waste Bottlle nnn B 6 Connect Power Cord and Connection B ME d oui a gt 81 u u mua o tmm B 8 BO AUTE DC QM RE 10 B9 Replenish Rinse S l Omn u u uu uu 11 B 10 gt uuu uu uuu uu 13 B 11 Set Reagent Rack and Reaction Tube B 13 B 12 Install Sampler with ID Bar Code Scanner Option B 14 CA 500 Series S M Revised December 2001 g APPENDIX INSTALLATION B 1 Check Before Installation Based on the following check list check the packings before installation B 1 1 Unpacking Check List Table B 1 Unpacking Check List Description Quantity Check 117V 220V 240V 461 2047 7 500 Operator s Manual 266 5293 0 Fuse 250V 3 15 19195 Europe 2 2 266 5106 0 Fuse 250V 6 ST4 6 3A N1 NAmer 2 663 0213 6 HolderCA 500 for 13 mm diameter tube 1 1 1 369 5982 2 Indication Mark
43. 1 LID NO 9 5 BOTTLE TANK A RINSE 2L BLUE 1 INSTRUCTION LABEL 7 1 CAUTION MARK NO 208 1 INSTRUCTION LABEL 1 JAPANESE CAUTION MARK NO 208 CAUTION MARK NO 16 FILTER ASSY FOR RINSE BOTTLE NON RETURN VALVE MFP 6 V UNSALABLE RINSE BOTTLE ASSY CA 5H 5L RINSE BOTTLE ASSY CA 5H 5L EU UK RINSE BOTTLE FLOAT SWITCH ASSY 5L LID NO 9 BOTTLE TANK RINSE 5L BLUE BOTTLE TANK RINSE 5L BLUE EU UK INSTRUCTION LABEL 7 CAUTION MARK NO 208 INSTRUCTION LABEL 1 JAPANESE CAUTION MARK NO 208 CAUTION MARK NO 16 FILTER ASSY FOR RINSE BOTTLE NON RETURN VALVE MFP 6 V UNSALABL Q WASTE BOTTLE ASSY CA 5H 2L WASTE BOTTLE ASSY CA 5H 2L EU UK WASTE BOTTLE FLOAT SWITCH ASSY 2L LID NO 9 BOTTLE TANK A WASTE 2L RED INSTRUCTION LABEL 2 INSTRUCTION LABEL 3 JAPANESE UNSALABLE CAUTION MARK NO 16 1 cx x x WASTE BOTTLE ASSY CA 5H 5L WASTE BOTTLE ASSY CA 5H 5L EU UK WASTE BOTTLE FLOAT SWITCH ASSY 5L LID NO 9 BOTTLE TANK WASTE 5L RED BOTTLE TANK WASTE 5L RED EU UK INSTRUCTION LABEL 2 INSTRUCTION LABEL 3 JAPANESE CAUTION MARK NO 16 UNSALABL a T e X X X A 1 31 Revised June 2003 500 Accessories CA 5H Z Axis Position Adjustment Tool PM Note This tool is not included with CA 500 Accessories ECR303C012 TB200408 CA 500 Series S M A 1 32 Revised February 2004 TB200408 500 ACCESSORIES Draw
44. 2 O N 000 72 4 amp 1 88 290 1390 11 18 2 31 36 88 11 18 2 31 36 PART NO INDEX PART NO 663 0406 1 8 663 0407 4 663 0407 4 663 0408 8 663 0408 8 663 0410 6 663 0411 0 663 0412 3 663 0413 7 663 0415 4 663 0415 4 664 0167 9 8 664 0167 9 833 3895 6 913 1091 3 921 0351 8 941 0131 3 500 Series S M PART DESCRIPTION RINSE BOTTLE ASSY CA 5H 2L EU UK RINSE BOTTLE ASSY CA 5H 2L EU UK WASTE BOTTLE ASSY CA 5H 2L EU UK WASTE BOTTLE ASSY CA 5H 2L EU UK BOTTLE TANK RINSE SL BLUE BOTTLE TANK RINSE SL BLUE EU UK BOTTLE TANK WASTE 5L RED BOTTLE TANK WASTE SL RED EU UK DETECTOR BLOCK D DIMER 800NM DETECTOR BLOCK D DIMER 800NM FILTER ASSY FOR RINSE BOTTLE FILTER ASSY FOR RINSE BOTTLE SAMPLE RACK NO 3 W HOLDER 55 STANDARD SCATTERING STICK SET PAPER THERMAL F1 2 5 SOLENOID VALVE NO 14D PM A 4 6 UNIT Q TY I lI II ll lI 1 33 1 31 1 33 1 31 1 33 1 31 1 31 1 31 1 31 1 9 1 11 1 31 1 31 1 33 1 3 1 33 1 35 Revised February 2004 TB200408 NO WASTE BOTTLE ASSY CA 5H SL EU UK 1 8 21 268 6 13 15 13 154 33 35 323 354 488 1 8 7 17 11 OPTION 5 31 APPENDIX INSTALLATION To Cover CANA ct 1 Unpacking Check SU Lu
45. 2 Confirmation by the operator None 3 Confirmation by Service Engineer 1 Retighten the pulley of motor if it is loosened 2 When home position cannot be sensed even if the drive mechanism is functioned a Check the light shield plate is broken or not b If 5 V is not appeared the pin 2 and pin 1 of CN112 for PCB No 6362 or if the signal on the pin 2 and pin 3 changes from 5 V to 0 V when the sensor is shielded the PCB No 6362 is faulty If 5 V 0 25 V is appeared on the pin 2 and pin 1 and the signal on the pin 2 and pin 3 does not change the wiring cord wiring cord from CN19 on PCB No 4086 or the sensor is faulty 3 When the motor does not run a Any of motor PCB No 9265 wiring cord printer relay flat cable and PCB No 4086 is faulty Replace and confirm b Turn the pulley by hand If it does not move the motor or drive mechanism is faulty 4 Failure of the drive mechanism a Check for flaws on the shaft b If the axis is free from flaws check the bushing is all right or not C Check the piston No 28 is broken or not CA 500 Series S M 6 19 Revised December 2001 g 6 5 7 Check Syringe Unit Monitor Timing When starting analysis Monitor Method Compares the syringe cycles recorded on BBRAM and active operation cycle by the software CA 500 s Action Warning at each analysis 1 Probable Cause 1 The syringe cycles exceeded 300 000 2 Failure of PCB No 6362 2 Confirmation by the operator None
46. 27 1 33 1 33 1 21 1 39 1 36 1 39 1 36 1 19 1 37 1 37 1 33 1 5 1 5 1 5 1 11 1 11 1 11 1 7 1 11 1 11 1 11 1 11 1 11 1 7 1 9 1 5 1 5 1 5 1 5 1 9 1 17 1 25 1 27 1 25 1 3 1 17 1 15 1 23 1 19 1 35 1 19 1 17 1 19 1 21 1 3 1 39 1 5 1 35 O GQ N N lt gt b O N 1 2 amp N N N N Q O A 29 Revised February 2004 TB200408 ALPHABETICAL INDEX 1 gt 4 2 N 500 5 PARTS DESCRIPTION PRINTER ASSY PRINTER COVER ASSY PRINTER FTP 421MCL001 PULLEY 1329A PULLEY DM1329 PULLEY NO 143 PULLEY NO 185 PUSH VIAL PV 10 REACTION TUBE TRASH BOX REAGENT RACK ASSY REAGENT STAGE ASSY REAR PANEL DM0933 CA5H RINSE BOTTLE ASSY CA 500 RINSE BOTTLE ASSY CA 5H 2L RINSE BOTTLE ASSY CA 5H 2L RINSE BOTTLE ASSY CA 5H 2L EU UK RINSE BOTTLE ASSY CA 5H 2L EU UK RINSE BOTTLE ASSY 5 5L RINSE BOTTLE ASSY CA 5H 5L RINSE BOTTLE ASSY CA 5H 5L EU UK RINSE BOTTLE ASSY CA 5H 5L EU UK RINSE BOTTLE FLOAT SWITCH ASSY 2L RINSE BOTTLE FLOAT SWITCH ASSY 5L RINSING CUP ASSY RUBBER TUBE NO 7 SAMPLE RACK NO 3 W HOLDER 55 SAMPLE RACK S
47. 32 X3 32 F7391 SOLENOID VALVE ASSY VOLUMET HYDRAULIC CONNECTOR NO 23 RUBBER TUBE NO 7 TUBE TEFLON 1 5MMID X 2 5MMOD TUBE SILICONE 6MMID X10MMOD PCB NO 6362 PCB NO 6373 AC INLET ASSY VOLUMETRIC PISTON ASSY PRESSURE PUMP ASSY MAIN UNIT FAN ASSY BATTERY LITHIUM CR23500SE CJ2 BATTERY LITHIUM CR17450SE 2 CJ2 PCB NO 7015 PCB NO 7015 2 FLASH MEMORY CHAMBER NO 4 SUPPORT NO 247 CA 500 PRESSURE CHAMBER ASSY PCB NO 6350 WITH ROM PCB NO 6350 WITH ROM FOR CA PCB NO 6375 ASSY above when the stock is depleted Flash Memory added with CA 550 560 upper compatible from program Ver 00 13 FOR 117 VAC 220 VAC FOR 100 VAC New CPU board PCB NO 6373 is mounted in following instruments CA 510 S N A1300 and thereafter CA 520 S N A1018 and thereafter CA 530 S N A1805 and thereafter CA 540 S N A3405 and thereafter CA 550 S N A1001 and thereafter CA 560 S N A1001 and thereafter CA 500 Series S M A 1 5 Qty per Unit 10 n gt Revised December 2003 ECR303K033 500 Chassis 1 2 AA c ii LT Details of Part C Details of Part D S u E 7 gt E lt 7 LI 1 ELI I 2 uL c NI D
48. 4 27 Revised December 2001 4 3 13 Position Adjustment Procedure of Catcher 29 immunoassy Adjustment Parameter Catcher Position XYZ pulses of Detector Block Summary Adjust the catcher XY and Z positions of the detector block by setting the reaction tube to the catcher Standard Position X direction 5 pulses to the left of the line where the left surface of the reaction tube when descended agrees the interior surface of the immunoassay well Y direction The center of the catcher agrees the center of the reaction tube when the reaction tube is descended Z direction 2 pulses above the line where the bottom of the reaction tube agrees to the bottom of the immunoassay well The upper edge of the reaction tube brim should be aligned with the lower surface of the upper catcher part 1 XYZ Adjustment X Correction 1 Place the reaction tube to the catcher 2 Verify that the 29 immunoassy is shown on the left center of the screen If not change to 29 immunoassy by using Pos and Pos keys 3 Move the catcher to the setting position by using XY TEST key 4 Use 7 IV lt and gt keys to adjust the reaction tube placed to the catcher to become the center of the immunoassy well 5 Press Z TEST key to descent the catcher 6 Press Tube Free and Tube Catch keys to release and catch the reaction tube a Y direction Use T and 4 keys to adjust the center of the reaction tube agrees the cen
49. 6 Y5 gt 06 o o AB EE BASE RASS 4 Revised December 2001 8 500 Main unit Chassis 2 2 By amp Lo ME Si Us Tit 19 2 MOOD D CA 500 Series S M Revised December 2003 ECR303K033 500 Main unit Chassis Assy 2 2 lt gt ISI gt 442 5475 1 442 5315 1 442 1403 8 442 5290 6 266 5045 0 266 5106 0 266 5293 0 662 2209 1 662 2208 7 266 3536 6 266 3533 5 322 9150 1 663 0197 3 442 5292 3 442 5452 5 442 5416 1 442 5280 9 442 5279 4 663 0198 7 442 3433 7 442 3307 4 442 5452 5 442 5295 4 662 0221 9 662 0287 4 663 0195 6 663 0164 1 663 0191 1 663 0196 0 289 9170 6 289 9169 1 662 0225 3 662 0278 1 443 0823 8 365 1333 3 662 0168 8 662 0276 3 662 0288 8 used with CA 550 560 upper compatible and will be replaced with the old PCB written Drawing No Description 6 7 TUBE 3MMID X 6MMOD TUBE SILICONE 2MMIDX5MMOD CLR CONNECTING TUBE NO 3 TUBE SILICONE 4MMID X 8MMOD FUSE 125 6 UL TSC 6A N4 FUSE 250V6 3A ST4 6 3A N1 N A FUSE 250V3 15A NO 19195 EUROP TRANSFORMER POWER ASSY 100V TRANSFORMER POWER ASSY 200V FUSE HOLDER CAP 031 1666 N AME FUSE HOLDER CAP 031 1663 EUROP WIRING CORD COVER VACUUM PUMP ASSY TUBE SILICONE 1 5MMID X 6MMOD TUBE TEFLON 4 5MMID X 2 5MMOD TUBE TEFLON 1 2MMID X 2 0MMOD TUBE SILICONE 2MMID X 3MMOD TUBE SILICONE 1
50. 7 lt and gt keys to adjust the reaction tube placed to the catcher to become the center of the sample incubation well 5 Press Z TEST key to descent the catcher 6 Press Tube Free and Tube Catch keys to release and catch the reaction tube a Y direction Use T and keys to adjust the center of the reaction tube agrees the center of the catcher Figure 4 3 20 Y Direction Adjustment CA 500 Series S M 4 24 Revised December 2001 b X direction Use lt and gt keys to adjust the horizontal position of catcher The catcher once ascends and then descends by pressing Z ADJUST key Adjust the reaction tube position in X direction to touch the left part of the inner wall of the incubation well by repeating this operation Catcher Heaction Tube Rack Figure 4 3 21 X Direction Adjustment Zdirection Use Catcher DOWN key to confirm the position where the reaction tube hit the bottom of the incubation well Touch around the incubation well to confirm the vibration of the hit or touch the reaction tube to verify that there is no more play Press Catcher UP key for 5 times Press Z Adjust key for 2 or 3 times to confirm that the reaction tube does not hit the bottom of the incubation well The Z position can be also adjusted by using Tube Catch key and Tube Free key and aligning the lower edge of the reaction tube brim with the upper surface of the lower catcher part Lower Edge
51. 7015 MEMORY BACK UP 5 Switching Control BATTERY Under 4V Detector Circuit PCB No 6350 PRCN PRCN 1 Interface PCB No 6375 PRCN 3 LCD LCD Touch Panel Voltage PCB No 9263 Contrast VR Signal Touch Panel Interface RS232C Transmitter RS232C Connector Receiver to Host Computer VD Unit Transmitter ID Unit Receiver Revised December 2001 8 3 8 3 Circuit Explanation 1 2 3 4 5 6 7 8 9 CPU 0201 The TMP68301AF 16 TOSHIBA is used Central Processing Unit CPU with the clock frequency of 16 MHz This CPU includes 68HCO000 as a core SIO PIO CTC Interrupt Controller Address Decoder etc Clock Frequency Generator Circuit X201 U212 213 320 The following clock frequencies are generated divided from the 32 MHz oscillator e 16 MHz CPU Clock e 16 MHz Clock for Motor Controller e 8MHz for LCD Controller and Standard CLK for driving ID Unit Motor e 4MHz CPU Clock for controlling temperature e 2MHz for LCD Controller e 500 KHz Clock for Motor Controller 4 91 MHz is used for each CLK of two A D Converters respectively Interrupt Controller U201 202 209 This function is performed by using the interrupting function built in the CPU and the interrupt controller The interrupt controller is used extended from INT2 of the CPU When the CPU receives INT it proceeds in accordance with the prescribed priority of the program
52. CA 500 Series S M A 1 28 Revised December 2001 8 500 Rear Panel for Bottles Code No Drawing Description Qty per NOTTE m 01 442 1450 3 1 CONNECTING TUBE NO 50 5 442 4003 7 2 NIPPLE NO 123 1 CA 500 Series S M A 1 29 Revised December 2001 8 CA 500 Rinse Bottle Assy 8 17479 2 500 Waste Bottle Assy Ld gt nn nDAO gt K Tr O p u 8 0 3 ANN amp x N Revised December 2001 8 1 30 CA 500 Series S M RINSE BOTTLE ASSY amp WASTE BOTTLE ASSY Drawing Description Qty per Unit Code No 663 0209 1 8 663 0407 4 662 2220 2 424 4679 6 424 9150 0 369 8604 6 369 8326 1 369 8601 5 369 8326 1 369 8016 8 664 0167 9 443 2804 4 8 663 0402 6 663 0405 7 662 2409 1 424 4679 6 663 0410 6 663 0411 0 369 8604 6 369 8326 1 369 8601 5 369 8326 1 8 369 8016 8 8 664 0167 9 8 443 2804 4 663 0210 5 663 0408 8 662 2221 6 424 4679 6 424 9151 3 369 8602 9 369 8603 2 369 8016 8 8 663 0403 0 663 0406 1 8 662 2410 6 8 424 4679 6 663 0412 3 663 0413 7 369 8602 9 369 8603 2 8 369 8016 8 For 117V amp For 220 240V 8 TB200203 ECR301K074 ECR303F001 CA 500 Series S M RINSE BOTTLE ASSY 5 2L 1 RINSE BOTTLE ASSY CA 5H 2L EU UK 1 RINSE BOTTLE FLOAT SWITCH ASSY 2L
53. Control Circuit 0401 412 This circuit amplifies the four temperature sensor signals for Reagent Cooler Unit Detector Block Thermister and Probe Nozzle converts them to the digital signals by the 13 Bit A D converter 0412 analyzes them at the Temperature control CPU 00401 and outputs the control signals for Detector Block heater Probe heater and Peltier cooler from each port Also the temperature control CPU sends each sensor temperature data and the sensor controlled value by the interface U402 403 404 with the Main CPU 201 As the sensors for Cooler Unit Detector Block and Thermister the centigrade temperature sensor IC LM35DZ is used and the sensor signal is amplified by 8 5 times at the amplifier unit In the case the sensor signal is cut off each sensor signal line is pulled up or pulled down to avoid over heating or over cooling As the temperature sensor for the Probe a thermister is used Approximately 100 pA constant current is flowed in the thermister and the voltage is amplified by three times at the amplifier unit In the case the thermister is disconnected or to avoid the thermal runaway when overheating due to the abnormal control the voltage is compared by the comparator U408 and the Probe control signal is forced to turn OFF when abnormal voltage occurred Each control signal for Detector Block heater Probe heater and Peltier cooler can be checked by the LED status D401 D402 and D403
54. D CL B 11 i N ll 9n ls CA 500 Series S M A 1 6 Revised June 2003 ECR303C033 500 Main unit Chassis Assy 2 2 Code No Drawing Description Qty per Unit No 663 0180 1 1 DRIVEARMASSY 1 662 0223 6 2 PCB 2134 662 0286 1 2 8 2157 663 0181 4 3 X AXIS SLIDER ASSY 663 0374 9 4 BASE DM1197B 663 0371 8 5 SHAFT B DM1090B 663 0370 4 6 PULLEY 1329A 663 0392 6 6 PULLEY DM1329 2 344 3529 8 7 HINGE R 45 N GREASE PCB used with CA 550 560 upper compatible and will be replaced with the old PCB written above when the stock is depleted TB200049 8 78200203 ECR303C033 CA 500 Series S M A 1 7 Revised June 2003 ECR303C033 500 Chassis Assy 2 2 CA 500 Series S M A 1 8 Revised December 2001 8 500 Chassis Assy 2 2 Drawing Description Qty per No 663 0161 0 1 COOLING SECTION ASSY 1 663 0217 1 2 TABLE LOCK MECHANISM ASSY 1 663 0199 1 3 RINSING CUP ASSY 1 663 0158 8 4 DETECTOR BLOCK 1 663 0159 1 4 DETECTOR BLOCK STANDARD 1 8 663 0399 1 46 DETECTOR BLOCK D DIMER 1 663 0415 4 4 amp amp DET
55. Data 752 Target Offset Gain Figure 4 2 1 Detector Gain Screen 1 To change or adjust a value Target Offset Gain select the value by using T and V keys The selected value is displayed in the reverse video and inputting by pressing and keys or inputting numerals in the Manual Entry screen is available 2 Selecta channel among CH1 Detector Well 1 gt Detector Well 2 gt CH3 Detector Well 3 gt CH4 Detector Well 4 gt CH5 Detector Well 5 gt CH6 Detector Well 6 in the order by pressing Channel Change key 3 Press Sensitive key to alternate the sensitivity of the selected channel in the order of High Gain Low Gain PT Gain T 4 Start the automatic adjustment for the offset gain value by pressing Auto Adjust key CA 500 Series S M 4 4 Revised December 2001 5 Press Manual Entry key to display the screen that the manual entry by numeric keys is available S Heady ysmeX Replace Rack YES Detector Gain ch 1 High Gain A D Data 752 Target Offset Gain 188 Figure 4 2 2 Manual Entry Screen 1 Pressing the numeric keys 0 to 9 can set the desirable value directly 2 Pressing C key can clear the set value 3 Press Enter key to settle the set value The set value cannot be settled if Quit key is pressed without pressing Enter key 4 Press Quit to return the previous screen This adjustment should be done more than 30 minutes after the po
56. December 2001 8 FLAG THRESHOLD CAUTION The change of flag threshold settings directly affects the analysis results and error detection method DO NOT change these settings without any assistance of authorized person 1 Press Special Operate Service Flag Threshold keys to start then the following screen will be displayed S Ready IP ysmeX Replace Rack YES Flag Threshold Settings for PT NC threshold resho 15 SC threshold 25 Minimum reportable time Masking time 5 0 Analysis L Print Return Method Figure 5 6 1 Flag Threshold Setting Screen Analysis Method Key Use to select the test item to change the settings 4 Key Use to move cursor to the desired item Bioactivity Method NC threshold SC threshold Minimum reportable time Making time JumpUp Reagent Correlation a Reagent Correlation b SLOW REACTION Algorithm Width Max Time START ANGLE Algorithm 1st Time Point 2nd Time Point Limit1 Limit2 DRIFT CHECK Algorithm 1st Check Point 2nd Check Point Width Limit Ratio EARLY CHECK Algorithm Check Point Limit Drifting Baseline Algorithm delta regwin swin maxbase derect Mixing Time for Sample Mixing Time for Reagent Calibration a Calibration b High Accurate Dilute ratio CA 500 Series S M Delta H level to detect No Coagulation error Delta H level to detect Slight Coagulation Curve error The minimum
57. Engineer 1 Remove any foreign matters on the barcode drive mechanism 2 Ifthe motor runs while barcode does not move retighten the pulley 3 Check whether the light shield for the home position sensor is damaged or not 4 Short circuit the pin 19 and pin 17 of the relay connector on the rail If this allows monitoring the detection of home position the sensor inside the sample rack drawer or wiring cord for ID reader is faulty 5 Short circuit the pin 13 and 11 of CN111 PCB No 6362 If this allows monitoring the wiring cord wiring cord with spiral is faulty otherwise PCB No 6362 15 faulty Check whether the drive mechanism shaft is free from flaws Check whether the slide of shaft bushing is smooth or not If the motor does not operate or unstable even when the shaft is free from problems any of ID motor assembly wiring cord for ID reader wiring cord wiring cord with spiral or PCB No 4086 is faulty 6 6 5 Monitor Timing When turning on power supply and changing the preset Monitor Method CPU communicate with Bar Code Scanner CA 500 s Action Warning 1 Probable Cause 1 Failure of barcode scanner 2 Failure of wiring cord for ID reader 3 Failure of wiring cord wiring cord with spiral 4 Failure of PCB No 6362 2 Confirmation by the operator None 3 Confirmation by Service Engineer Replace and confirm Otherwise confirm connections and
58. I O Motor Control Temperature Control 3 16 PCB No 6373 MAIN 2 CPU I O Motor Control Temperature Control A D 3 16 PCB No 7015 MEMORY Program 3 23 PCB No 9258 LED2 LED for scattered 9 3 23 PCB No 9259 LED1 LED for transmitted 191 3 24 PCB No 9260 X RELAY X Axis Relay cccccccsseeccesseecceneeeceeececsuseeesaeeeceaecesseeecseseessuaeessessesessages 3 24 PCB No 9263 VR LCD Contrast Volume a nnne nnne nnne nnns 3 25 PCB 9264 Z RELAY Z Axis Relay Z Axis Home Position 3 25 PCB No 9265 PR RELAY Operation Panel Syringe Motor SV 1 Relay 3 26 PCB No 9303 PR RELAY2 Operation Panel Syringe Motor SV 1 Relay 3 26 CA 500 Series S M Revised December 2001 SECTION 3 ELECTRONICS 3 1 PCB Locations Switching Regulator 505 5 Transformer LCA150S 12 LCA150S 24 XJCM BO Figure 3 1 PCB Location P
59. NO 2132 STANDARD PCB NO 2156 STANDARD CLOT AT3 PCB NO 2156 5 CIRCUITS DD 575NM PCB NO 2156 4 CIRCUITS DD 800NM COAGULATION LED ASSY PCB NO 2132 2 CIRCUITS PCB NO 2156 2 CIRCUITS CLOT PCB NO 2132 3 CIRCUITS PCB NO 2156 3 CIRCUITS AT3 DD DETECTOR THERMAL ASSY HEATER ASSY CHROMOGENIC LED ASSY D DIMER LED ASSY 575NM D DIMER LED ASSY 800NM CH6 FUSE THERMAL 125V5A TYPE210 WIRING CORD PD DW0458 above when the stock is depleted __ ECR TB 200203 CA 550 A1001 CA 560 A1001 3036037 Not applicable CA 500 Series S M A 1 11 Oo 2 c cl cl Revised October 2003 CA 500 Cooling Section Revised June 2003 ECR303C033 A 1 12 CA 500 Series S M CA 500 Cooling Section Code No Drawing Description Qty per 66 663 0161 0 1 COOLING SECTION ASSY 1 663 0162 3 1 COOLER ASSY THERMAL MODULE 1 663 0163 7 2 COOLING FAN ASSY 1 662 2206 0 3 COOLER THERMAL ASSY SERNSOR IC 1 426 3152 0 4 SILICONE GREASE THERMAL 800 8 1 348 5936 2 5 SCREW ROUND M3X15 100 663 0372 1 6 HEAT SINK 1113 1 A 399E018 399 015 CA 510 A1030 CA 520 A1003 530 A1393 CA 540 A2277 399 012 ECR303C033 CA 500 Series S M A 1 13 Revised June 2003 ECR303C033 Table Lock Mech X AXIS SLIDER ASSY CA 500 Series S M A 1 14 Revised December 2001 8 TABLE LOCK MECHANISM ASSY
60. No 954 for Reagent Rack 1 1 1 462 4842 7 Paper Thermal 1 2 2 1 1 265 4719 0 Power Cord 4622 007 0092 Europe 1 265472955 Power 1686 0 d t1 793 0012 1 PowrCordNo 4 NAme 1 541 1352 1 Push Vial 10 22 OD x40 high 2 2 2 541 0541 8 Reaction Tube 1000 60 60 60 663 0206 0 Reagent Rack CA 500 1 1 663 0209 1 Rinse Bottle 500 Assembly 1 1 663 0407 4 Rinse Bottle CA 500 Assembly EU UK 1 1 663 0402 6 RinseBotle CA 500 Assembly 5L 1 1 663 0405 7 Rinse Bottle CA 500 Assembly 5L EU UK MEE 663 0208 7 SampeTubeRackCASO 2 2 2 663 0211 9 Trap Chamber CA 0Assemby 1 1 66302073 TubeTrashCA 500 1 1 663 0210 5 Waste Bottle 500 1 1 663 0403 0 Waste Bottle 500 Assembly 5 1 1 Packed with CA 550 560 WWE S IN CA 500 Series S M B 1 Revised December 2001 g B 2 Installation Space To make maintenance and service easy give consideration to heat radiation by the instrument provide at least 50 cm clearance between the wall and the instrument s side panels rear and top pan
61. ON8Od N Vids NO N N IND 9NO T 6 ONSOd P 8NO SNO ZNO Jejuugd ung me NO 9NO SNO YNI ZNO poor S269 duing OSES ONGIA Y H INO ge a 2 soury Aieyeq 09 60LNO 90LNO 80LNO LOLNO i Li s ZOLNO ho 5407 899 ZOLNO 97 RON Z9 9 ON82d y QHVO8 NIVIN suni ZLLNO 1 lt 9655 54 OLLNO 0 5 uoaa SOLNO O N VLINO OZLINOSLINO SLINO 6LINO 193 1no o9 Buu s PPP rS einssaJd ainssald eseoNod ee 6L Ob eqni i TA INO O IN e e 9NO vHO Z Josueg f JeyeoH SHO us A 1 L H m 7 L nu Aa Josuag I X bs 8l 0c No ZNO gt INO uono l q gt eo se cues 95LZ ONSOd ZELZ ONSOd dd 0 9040 mo T i LNO 09 6
62. PCB No 6350 PRCN 1 Printer Control Board PCB No 6375 PRCN 3 Printer Control Board 3 7 1 Specification The operation of the printer and PCB No 6350 or PCB No 6375 are as follows 1 2 3 4 5 6 When the initializing is performed with the paper loading after power is turned ON the printer is ready to operate turning the READY signal to L and waiting for the input data Data transmitted from the host computer is handshaken by STROBE and READY signals and stored in the buffer memory in one byte steps When a full line data is reached LF OAH or ESC 1BH code is entered all data stored in the buffer is printed out If there is no data before LF code only line feed takes place When one dot line data is entered in case of a bit image Printing is performed in synchronism with the code wheel signal If the printer head is lifted up with the Head up lever during operation or when paper empty condition is encountered the power to the printer head is shut off and the motor stops resulting in the BUSY status This status is maintained until the above condition is cleared When cleared the status changes to READY When the buffer contains no print data the FEED signal is effective L level of the FEED signal shows BUSY status providing the paper feed by one line 9 dot lines If the motor is locked by paper jamming or other reason the printer will activate the ERROR signal and makes an emerge
63. Reaction curves CA 550 and CA 560 allow zooming in to view Rack number CA 550 and CA 560 only iv Quality control QC data QC chart Only CA 550 and CA 560 can carry markings on screen display about the data beyond the upper and lower limits of quality control In addition the CA 550 and CA 560 analyzers stores the data of slight coagulation errors Standard curve SC data SC chart Operation messages vii Error messages vii Maintenance information and various setting values ix Temperatures at incubation well heater pipette reagent cooler unit 3 Input Method Change select and set functions on each screen by LCD touch panel method lt lt CA 500 Series S M 1 11 Revised December 2001 8 15 Printing Function 1 Printing Method Graphic print by a built in thermal printer 2 Printed Data i Stored sample data the same as the measured data ii Quality control QC data QC chart iii Measured data Date Time Sample ID number Parameter name Measured data Reaction curve Analysis print data Rack number CA 550 and CA 560 only iv Standard curve SC data SC chart v Confirmation messages Error messages vi Maintenance information and various setting values CA 550 and CA 560 can print at each parameter 16 Quality Control Function 1 L J control or X control is possible using control material 2 Applicable parameters APTT Fbg TTO NT TT AT Ill 14 paramete
64. Relay to Z Axis Motor Signal Relay From PCB No 2134 Y Z RELAY from Tube Catch Sensor From PCB No 2157 Y Z RELAY2 Z Axis Home Pos Sensor Figure 3 18 PCB No 9264 Block Diagram 3 14 3 Setting and Adjustment Setting and adjustments are not necessary 3 14 4 LED and Test Point There are LEDs or test point 3 14 5 Assembly Drawing MEDICAL NICS n CO o 81 RELAY DPHITSC 9264 KADE IN JAPAN 14 9784 Figure 3 19 PCB No 9264 Assembly Drawing CA 500 Series S M 3 25 Revised December 2001 3 15 No 9265 RELAY Operation Panel Syringe Motor SV 1 Relay PCB No 9303 PR RELAY2 Operation Panel Syringe Motor SV 1 Relay 3 15 1 Function This PCB is used for relaying the signal of the operation panel relay Inverter for LCD Mechanical Stop Switch three kinds of Printer control line the syringe motor and solenoid valve 1 3 15 2 Block Diagram from Mechanical Stop SW No 2 T No 6350 PRCN 1 to Built in Printer PCB No PRCN 3 to Inverter for LCD lt to Syringe motor PCB No 4086 PS to Solenoid Valve 1 Figure 3 20 PCB No 9265 and 9303 Block Diagram 3 15 3 Setting and Adjustment Setting and adjustments are not necessary 3 15 4 LED and Test Point There are no LEDs or test point 3 15 5 Assembly Drawing PR REL
65. Transportation Function Sample tube is transported from the sample tube rack to the sample incubation unit by the Slide Catcher Method Reaction Tube Feeding Function 1 Reaction Tube Feeding Method Fed manually to Reaction Tube Rack 2 Number of Reaction Tube 2 racks containing 30 tubes each maximum 60 reaction tubes 3 Kinds of Reaction Tube Tube SU 40 for CA 1000 4 Detecting Reaction Tube Detected by Reaction Tube Detective Sensor Sample Plasma and Reagent Dispensing Function One dispensing pipette with the heating function moves up and down traverses and dispenses the sample and the reagent 1 Temperature Control Accuracy 37 0 1 0 C with ambient temperature of 15 30 2 Waiting Time for Setting Temp within 30 minutes 3 Volumetric Method Sample and reagent are aspirated dispensed and rinsed by the syringe 4 Volumetric Syringe 1 5 Pipette 1 Liquid Surface Detection Function The pipette has the liquid surface detection function so that it senses the meniscus automatically and then stops at a certain depth of the sample or the reagent Sampler Function 1 Sample Storing Method oysmex Rack 2 Maximum Sample Storage 1 rack 10 samples 3 Usable Collection Tubes The following types with inside diameter of 8 mm or more i 15 OD X 75 100 mm length ii 12 OD X 75 100 mm length 10 OD X 65 mm length The optional spacer is required Sample cup of 2 mL or 4 mL 4 Sample C
66. Tube Catch Error has occurred a Correct any mis positioning that has happened b Replace the catcher 2 When an error occurs though a tube is caught Tube Detection Sensor CN1 PCB No 2134 pin 16 GND and pin 4 5 V 0 V when a tube is detected PCB 9260 pin 16 GND and pin 4 5 V gt 0 V when a tube is detected CN105 PCB No 6362 pin 13 GND and oV gt 0 V when a tube is detected pin 1 CA 500 Series S M 6 12 Revised December 2001 g 6 4 6 Tube Release Error Position Monitor Timing Just after the reaction tube releasing operation Monitor Method Monitoring tube detection sensor condition CA 500 s Action Interruption 1 Probable Cause 1 E cupo RE E eie 10 11 12 A tube cannot be released Tube detection sensor is obstructed The waste box of tube is full The catcher is too dirty to function Mis position of catcher Defective catcher Failure of tube detection sensor Failure of PCB No 9264 Failure of PCB No 2134 Failure of PCB No 9260 Failure of X axis wiring cord Failure of PCB No 6362 2 Confirmation by the Operator 1 2 3 Empty the waste box if it is full of the reaction tube Remove anything that is obstructing the release operation Wash away any contamination on catcher by using alcohol 3 Confirmation by Service Engineer 1 When Tube Release Error has occurred a Correct any mis positioning of the catcher if that has happened
67. Unit Digit _ Calculation Method 1 Invalid Log Log point plotted graph 2 Invalid 3 Valid INR 4 Invalid mg dL Liner graph Auto Dilution Analysis 100 80 60 40 analysis times twice 2 Calculation Parameters Unit Digit Calculation Method 1 Invalid Log Log point plotted graph 2 Invalid 3 Invalid 4 Invalid Calculation Parameters Calculation Method 1 Valid Fbg C C pist X Log Log point plotted graph 2 Invalid 3 Invalid 4 Invalid Auto Dilution Analysis 200 150 100 50 33 3 analysis times twice 4 Calculation Parameters Unit Digit Calculation Method 1 Invalid Log Log point plotted graph 2 Invalid 3 Invalid 4 Invalid b TTO huge Saleulation Parameters Unit _ 1 Valid Log Log point plotted graph 2 Invalid 3 Invalid 4 Invalid Auto Dilution Analysis 150 100 50 25 12 5 0 analysis times 3 times CA 500 Series S M 5 32 Revised December 2001 g 6 Calculation Parameters LS Digit _ Calculation Method 1 Valid Log Log point plotted graph 2 Invalid 3 Invalid 4 Invalid Auto Dilution Analysis 150 100 50 25 12 5 0 analysis times 3 times 7 Calculation Parameters Digi Calculation Method 1 Valid AT 119 Liner graph 2 Invalid 3 Invalid 4 Invalid Auto Dilution Analysis 150 100 50 25 12 5 0 analysis times 3 times
68. according to the setting pulses When the probe is not at the home position it will move to the setting value after returning to the home position CA 500 Series S M 4 11 Revised December 2001 13 XY ORG Key Return XY drive to home position When this key is pressed Y axis then X axis returns to the home position after Z axis returns to the home position 14 Pos Pos Key Switch setting position from 1 to 29 15 Either Pipette or Catcher Key Move the pipette or the catcher Moves 1 pulse by 1 press Pipette Adjustment Pipette UP Pipette DOWN e Catcher Adjustment Catcher UP Catcher DOWN 16 Arrow Keys Move 1 pulse by 1 press 0 085 mm pulse Move X axis to the left away from the home position gt Move X axis to the right toward the home position T Moves Y axis toward the home position 4 Moves Y axis away from the home position Enter Pulses Key Press to enter pulses manually using the numeric keys 18 Display number of pulses stored in EEPROM to be updated by fixing the set value Z TEST key Press to move to the Z position currently set This is not for changing the set value but for check only 20 MODE CHANGE key Press to change modes Fine Adjustment Individual position Mode Set each position for 29 points Basic Position Adjustment Mode Set the basic position for each block By this setting the accompanying position within the block can be
69. axis drive mechanism CA 500 s Action Emergency stop 1 Probable Cause Drive mechanism operation is obstructed Loosened pulley of motor Failure of PCB No 2134 Defective light shield Flaw on shaft Failure of slider Failure of PCB No 9260 Failure of X axis wiring cord Failure of PCB No 6362 0 Failure of Y axis motor assembly 1 Failure of PCB No 4086 c ge 2 Confirmation by the Operator 1 Remove the obstruction in Y axis drive mechanism 2 Turn off the power supply then turn it on again 3 Confirmation by Service Engineer 1 Retighten the screw of the pulley of motor 2 If home position cannot be detected even when the drive mechanism is operated a Check whether the light shield is defective or not Suspect Part Test Points Expected Value Position sensor PCB No 2134 pin 19 and 20 GND 5 V gt 0 V when the sensor is shielded PCB No 9260 pin 19 and 20 GND 5 V gt 0 V when the sensor is shielded CN105 PCB No 6362 pin 6 and pin 14 GND 5 V gt 0 V when the sensor is shielded 3 When the motor does not operate a Any of motor PCB No 2134 X axis wiring cord 18 wire cable or PCB No 4086 is faulty Replace and confirm b Turn the pulley by hand If it does not move the motor or drive mechanism is faulty 4 Failure of the drive mechanism a Check for flaws on the shaft b If the shaft is free from flaws the problem is in the bushing
70. b Replace the catcher When an error occurs although a tube is released a sensor functions up to 30 mm apart from tubes Keep away any objects that reflect light to cause release error Suspect Part Test Points Expected Value Tube Detection CN2 PCB No 9264 pin GND and pin 2 5 V gt 0 V when tube is oensor detected CN1 PCB No 9264 pin 13 GND and pin 8 detected 4 PCB No 2134 pin 13 GND and pin 8 detected CN1 PCB No 2134 pin 16 GND and pin 4 detected CN1 PCB No 9260 pin 16 GND and pin 4 detected CN105 PCB No 6362 pin 13 GND and pin 1 5 V 0 V when a tube is detected CA 500 Series S M 6 13 Revised December 2001 g 6 5 DISPENSING ERRORS 6 5 1 No Sample Rack Position Monitor Timing At sample aspiration Monitor Method Detects liquid level by the capacitance liquid level detection sensor CA 500 s Action The sample is not analyzed 1 Probable Cause 1 Specimens are not placed Plasma volume is insufficient Failure of sample probe Failure of PCB No 2134 Failure of Y Z relay harness Failure of PCB No 9260 Failure of X axis wiring cord Failure of wiring cord flat cable Failure of PCB No 6362 OND 2 Confirmation by the operator 1 Place the specimen 2 Check whether the sample location rack number matches its registration or not 3 Confirmation by Service Engineer 1 Monitor the liquid sensor function in the Service mo
71. hold dilution mode PFC CA 500 Series S M 1 4 Revised December 2001 8 3 Measurement Time 1 Maximum Measurement Time in Standard Mode PT 100 seconds 120 seconds in CA 550 and CA 560 Fbg 100 seconds Others 190 seconds ATIII 30 seconds 2 Maximum Measurement Time in Automatic Extended Mode Parameters 600 seconds 4 Accuracy When control plasma N is measured consecutively 10 times measurement error of the average time second should lie within the following ranges The ambient temperature must be 25 10 PT 896 or less APTT 896 or less 5 Reproducibility Coefficient of variation when control plasma N is measured consecutively 10 times should lie within the following ranges with 95 confidence if specified reagents are used The ranges should be observed when measuring was performed on 10 to 30 ug mL of diluent sample with SFDP and PFDP and on 500 to 1000 ug mL of diluent sample with D Dimer PT APTT second CV within 2 TTO NT second CV within 4 Fbg second CV within 496 Factor 1 V VII VIII IX X XI XII second CV within 590 TT second CV within 1096 BXT second CV within 4 LA1 LA2 second CV within 4 PCc second CV within 5 CV within 5 APL 90 CV within 5 CV within 5 BCPC 96 CV within 596 Hep IU mL CV within 5 SFDP ug mL CV within 10 PFDP ug mL CV within 10 D Dimmer ug L ug mL CV within 10 CA 500 Series S M 1 5 Revised Decem
72. identify failed locations by a voltmeter CA 500 Series S M 6 23 Revised December 2001 g 6 6 6 Change Sample Rack Monitor Timing Monitor every 50 msec during interruption Monitor Method 1 The micro switch in the sample rack table 2 Photo interrupter incorporated is shaded by the light shield attached to the sample rack drawer CA 500 s Action Warning at each analysis 1 Probable Cause 1 Failure of sampler rack sensor assembly Failure of wiring cord wiring cord with spiral sample rack drawer is not opened or closed Defective light shield of sample rack drawer Failure of sensor Failure of solenoid valve assembly Failure of PCB No 6362 CON O O1 B W The sampler rack is not replaced 2 Confirmation by the operator 1 2 Place the sampler rack properly Place the sampler rack drawer properly 3 Confirmation by Service Engineer 1 2 Check the dirt on sample rack table and or it is free of foreign matters Short circuit the pin 20 and pin 18 of relay connector If it can be monitored on the switch sensor screen the sample rack drawer might be faulty Check the harness and sample rack sensor If the above step 2 does not solve the trouble short circuit the pin 14 and pin 12 of CN111 on PCB No 6362 If this solves the trouble the wiring cord wiring cord with spiral is faulty If not the PCB No 6362 is faulty Check whether the light shield is damaged
73. it is in progress press Cancel key NOTE Filing the hydraulic line with rinse solution takes 35 sec or so Ready HC IP Sysmex Replace Rack YES DEN Supply Liquid Water supply running Cancel Figure B 17 Water supply running Message Screen 6 Water supply is completed When water supply is over the Special Operation Menu screen will return CA 500 Series S M B 12 Revised December 2001 8 B 10 Set Tube Trash Drawer Set the furnished tube trash drawer E Tube Trash Drawer Figure B 18 Setting the Tube Trash Drawer B 11 Set Reagent Rack and Reaction Tube Rack Set the furnished reagent rack and reaction tube rack Reaction Tube Rack Que FH Say Reagent Rack Figure B 19 Setting the Reagent Rack and Reaction Tube Rack Affix Indication Mark No 954 on the reagent rack CA 500 Series S M B 13 Revised December 2001 8 12 Install Sampler with ID Bar Code Scanner Option An optional Bar code Scanner is installed on the CA 510 or CA 530 as follows 1 Remove the left side panel of the CA 500 main unit Loosen the screws as shown to remove the panel a gt 7 Figure B 20 Removing Panel 2 Remove the sampler 1 Pull the sampler forward Pull it out until it stops against the stopper 2 Remove the duct cover for the sampler slide rail by sliding it backward VAG Duct e Figure B 21 Removing the Duct Co
74. of Z adjuster Continuous Ready IP Replace Rack OK Reagent Z continuous adjustment oysmex Adjuster Z Adjuster V 4mL vial 60uL Adjust Mode Continuous V Single KE Set Return Figure 4 3 14 Reagent Z continuous adjustment Press Set to carry out Auto Z axis Position Adjustment Press Return gt Fix to save parameters When there is no available Z axis Position Adjustment Tools carry out the adjustment as below 1 2 3 4 Dispense 60uL of distilled water into the 4mL sample cups and set the sample cups for Reag1 through Reag10 Rinse Buffer 12 places Press Z adjust and check the check boxes of 4mL Continuous Press Set to carry out Auto Z axis Position Adjustment Press Return Fix to save parameters When Single is selected Z position adjustment at each of R1 to R10 can be performed individually CA 500 Series S M 4 18 2 Revised May 2003 303C012 4 3 7 Position Adjustment Procedure of Pipette 10 wash 1 XY Adjustment 1 8 Select Special Operate gt Rinse amp Prepare from the Main Menu and supply rinse reagent into the probe rinse cup outside Verify that the 1O0 wash is shown on the left center of the screen If not change to 10 wash by using Pos and Pos keys Move the pipette to the setting position by using XY TEST key Use 1 4 lt
75. or not on the sample rack drawer rear side If the signal on the pin 2 and pin 3 of the relay connector for solenoid assembly does not change even photo interrupter is shaded by the light shield the solenoid valve assembly or sensor is faulty If the above step 5 does not solve the trouble short circuit the pin 5 and pin 6 of CN112 on PCB No 6362 If this solves the trouble the wiring cord wiring cord from CN19 on PCB No 4086 is faulty If not the PCB No 6362 is faulty CA 500 Series S M 6 24 Revised December 2001 g 6 6 7 Replace STAT Sample Monitor Timing Monitor every 50 msec during interruption Instrument monitors when next STAT sample is analyzed whether previous STAT sample is removed Monitor Method Photo interrupter incorporated is shaded by the light shield attached to the sample rack drawer CA 500 s Action Warning at each STAT sample analysis 1 Probable Cause 1 The light shield cover was opened when replacing Defective light shield of sample rack drawer The sample rack drawer is not opened or closed Failure of solenoid valve assembly Failure of PCB No 6362 W The STAT sample is not replaced 2 Confirmation by the operator 1 2 Place the sampler rack drawer properly Remove the foreign matters 3 Confirmation by Service Engineer 1 2 3 4 Check the dirt on table rock mechanism and or it is free of foreign matters Check whether the l
76. reporting time for reporting Analysis is not done for the raw data after adding reagent during the time period One of the Standard Curve error JumpUp judgment areas Coefficient of delta OD compensation Offset of delta OD compensation The delta OD after compensation a x Detected delta OD b Use of SLOW REACTION Algorithm Width of check for SLOW REACTION Algorithm Threshold of error for SLOW REACTION Algorithm Use of START ANGLE Algorithm otart of the check range for START ANGLE Algorithm End of the check range for START ANGLE Algorithm Error threshold 1 for START ANGLE Algorithm Error threshold 2 for START ANGLE Algorithm Use of DRIFT CHECK Algorithm The center 1 of the check range for DRIFT CHECK Algorithm The center 2 of the check range for DRIFT CHECK Algorithm Check range for DRIFT CHECK Algorithm Threshold of error for DRIFT CHECK Algorithm Use of EARLY CHECK Algorithm Check Point for EARLY CHECK Algorithm Threshold of error for EARLY CHECK Algorithm Use of Drifting Baseline Algorithm Threshold for Drifting Baseline Algorithm Width of baseline interval for Drifting Baseline Algorithm Width of evaluation interval for Drifting Baseline Algorithm Maximum slant of linearization function for Drifting Baseline Algorithm The slant of reaction curve for Drifting Baseline Algorithm The mixing time for sample The mixing time for reagent The slant of calibration The segment of calibration
77. set automatically Tube Trash acter Tube Ti poh 8 Ors Detection Well Cetechon Vi ell i C Immunoassy noe cH 2 SU p Detecting eo wa 4 Y Dispenseg el e 4 i oxnab CLEAN H oder a Prete Rra Ouida He 4 h 10 Burar Hoar 4 Frob e Anse Cunt inside STAT Rack Figure 4 3 2 Table Positions CA 500 Series S M 4 12 Revised December 2001 4 3 4 Position Adjustment Procedure of Pipette 1 blood 1 2 blood 10 and 3 blood stat 1 XYZ Adjustment CAUTION 1 When setting the sample rack be sure that the plate is inserted to the groove of the rack correctly It may cause the pipette to be bent Sample Rack Figure 4 3 3 Setting Sample Rack 2 When setting the 15 diameter tube into the sample rack set the tube straight into the sample rack 1 Pour 50 uL of distilled water into the 4 mL sample cup or 50 of distilled water into the 15 mm diameter test tube and set it into the sample rack No 1 Set a cup or a tube for the customer s use 15 mm Diameter Test Tube 50 uL of Distilled Water 2 cm Sample Cup 50 pL of Distilled Water Figure 4 3 4 Sam
78. signal from PCB No 6362 MAIN or PCB No 6373 Main 2 The vacuum and pressure pumps are operated at AC 100 V 3 6 4 Setting and Adjustment Setting and adjustments are not necessary Refer to Section 4 to verify each voltage 3 6 5 LED and Test Point 1 LED No LED is used Test Point TP1 GND 2 CA 500 Series S M 3 13 Revised December 2001 3 6 6 Assembly Drawing T E gt o 2 n 12 a pae 12d u at o 3 912 4t i 24 e 8 WW 21H us rd m Oo 4k T ro 4 1 LSB 11 9 va al 6 Ww g 5 wu 923 B S u 5 u T SSH o e 653 z E ny 5 Is gJ gt amp e 80 3 4 o 58 r ov a 942 90 AA y S Ku scu 10 059 2 gt 5 PEL j owe E EET n 5 pru AA COT i 3 PINI B EN S n gt pi Sty z 5 THH S0 pid 02 dk af A 9782 CA 500 Series S M Figure 3 9 PCB No 4086 Assembly Drawing 3 14 Revised December 2001 37
79. surface CN1 PCB No 9260 pin 16 GND and pin 5 surface CN105 PCB No 6362 pin 13 GND and pin 2 surface CA 500 Series S M 6 16 Revised December 2001 g 6 5 4 No Reaction Tube Monitor Timing Just after the catching operation at reaction tube rack Monitor Method Tube detection sensor monitors a reaction tube CA 500 s Action Interruption 1 Probable Cause 1 A reaction tube cannot be caught Tube catch operation is obstructed 3 The catcher tried to catch a reaction tube from the middle of tube rack but it failed 4 Notube 5 The number of tube rack exceeds 60 during analysis 6 The catcher is too dirty to function 7 Mis positioned tube 8 Failure of catcher 9 Dirty of tube detection sensor 10 Failure of tube detection sensor 11 Failure of PCB No 9264 12 Failure of PCB No 2134 13 Failure of Y Z relay harness 14 Failure of PCB No 9260 15 Failure of X axis wiring cord 16 Failure of wiring cord flat cable 17 Failure of PCB No 6362 2 Confirmation by the operator Remove reaction tubes that are standing in the way Remove anything that is obstructing the catching operation Clean any contamination by alcohol or the like Place the tubes in order Place the tubes properly in the quantity required for testing O AOUN If sample discharged in the tube rack or on the reagent stage clean them 3 Confirmation by Service Engineer 1 When catching error has occurred a Correct a
80. the pump is failed if not the drive circuit is failed Vacuum pump only operates when rinse cup liquid draining Check the voltage in this timing CA 500 Series S M 6 2 Revised December 2001 8 62 TEMPERATURE ERRORS 6 2 1 Temperature Error High Incubator Temperature Error Low Incubator Monitor Timing When READY 1 minute interval When analyzing At time of reagent dispensing Monitor Method A D converter reads the thermistor data embedded in the sample probe as follows Room temperature less than 30 Temperature error when exceeds the range 36 0 38 0 Room temperature above 30 Temperature error when exceeds the range 36 0 40 0 500 When the error occurs before the analysis the analysis does not start During analysis operation is continued with Temperature Error added to stored data 1 Probable Cause Room temperature became outside the range between 15 35 Thermistor failure Heater failure Failure of PCB No 2134 Failure of X axis wiring cord Failure of PCB No 9260 Failure of PCB No 6362 Failure of PCB No 4086 2 Confirmation by the Operator 1 Confirm room temperature by checking temperature displayed on the main unit 3 Confirmation by the Service Engineer 1 Check the main unit fan is operating or not if not inside temperature rises causing it impossible to keep the detector at 37 CA 500 Series S M 6 3 Revised December 2001 8 6 2 2 T
81. the sample cup Figure 4 3 9 Pipette Tip Position 5 Press Z TEST key to descent the pipette The pipette detects the 60 uL of distilled water and stops 6 Use 1 lt and gt keys to adjust the pipette tip to become the center of the sample cup 7 Press Z ADJUST key to ascend and descend the pipette Verify the pipette is placed at the center of the sample cup 8 Press XY ORG key to return the pipette head to the home position 9 Adjust 5 reag 9 and 6 reag 10 in the same way CAUTION 1 Descent the pipette lower limit to the lowest for Z axis adjustment value Adjust after executing Section 4 3 4 Position Adjustment Procedure of Pipette 3 Pipette Lower Limit Adjustment when it stops before detecting liquid surface Set 650 pulse for the pipette lower limit of the reagent rack CA 500 Series S M 4 16 Revised December 2001 4 3 6 Position Adjustment Procedure of Pipette 7 reag rinse buffer Continuous Z position adjustment is possible on software version 00 14 or later Refer to 4 3 6 2 1 XY Adjustment 1 sample cup holder to the CA CLEAN Holder Place 60 uL of distilled water into the 4 mL sample cup 60 uL of Distilled Water 7 Sample Cup Figure 4 3 10 Sample Cup with 60 Distilled Water 2 Verify that the 7 reag rinse is shown on the left center of the screen If not change to 17 rinse by using Pos and Pos keys 3
82. to Service Menu screen CA 500 Series S M 5 21 Revised December 2001 g 510 LED CALIBRATION SETTING When entering the Service Mode the setting of Calibration is added in customer setting menu 1 Enter the service mode See Section 5 1 1 2 From the main menu press Special Menu Special Operate LED Calibration keys then the LED Calibration Menu screen will be displayed Replace Rack YES LED Calibration Calibration Detector State Calibration Setting Figure 5 10 1 LED Calibration Menu Screen 3 Press Calibration Setting key then the LED Calibration Setting screen will be displayed S Ready IP Replace Rack YES LED Calibration Setting LED Calibration ON Adjustment Cycle Warning Limit DA 7 8 9 Error Limit DA 4 5 6 50 1 2 3 0 Quit Figure 5 10 2 LED Calibration Setting Screen T and Keys Use to move cursor The selected item is displayed in reversed CA 500 Series S M 5 22 Revised December 2001 g Next Key Use this key to display the following parameters Key to be Used Selection Default LED Calibration Select whether to use LED Calibration Next Option ON OFF ON LED Calibration key will be displayed on Special Operation Menu screen when the setting is ON Adjustment Cycle The message to urge
83. ug L 10 or less otability against Power Source Variation Variation of measurement Activation 9o for AT 11 lies within the following ranges when the rated voltage changes at 10 Measurement at 10 or 10 Measurement at rated voltage 100 Measurement at rated voltage PT APTT second 8 or less Fbg HpT second 1090 or less AT III 96 10 or less D Dimmer ug L 1096 or less CA 500 Series S M 1 6 Revised December 2001 8 7 Analysis Mode and Sample Throughput 1 Analysis Mode 5 parameters are selected out of 7 parameters 14 parameters in CA 550 and CA 560 to perform random analysis 2 oample Throughput Maximum Throughput approx 54 tests hour when PT single parameter is measured Mean Throughput PT APTT Fbg approx 40 tests hour when three parameters are measured at the same time Mean throughput in this case means the mean throughput at the point of which an hour has passed from a Start key entry 8 Time Resolution 1 Coagulation Time resolution is as follows depending on the elapsed time from the start of measurement 0 1 second 2 through 120 seconds 0 2 second 120 through 240 seconds 1 0 second 240 through 600 seconds 2 Chromogenics Substrate Method and Immunoassay Method The unit can continue performing sampling every second up to 600 seconds at maximum 9 Compensation functions 1 Setting of Coagulation Detection End Point The coagulat
84. 0 gt gt gt I gt lI lI gt gt 1 25 1 3 1 25 1 7 1 7 1 23 1 23 1 33 1 33 1 33 1 3 1 37 1 35 1 31 1 33 1 31 1 33 1 31 1 33 1 31 1 33 1 31 1 31 1 9 1 5 1 33 1 3 1 35 1 3 1 3 1 3 1 3 1 38 1 3 1 33 1 33 1 39 1 39 1 13 1 21 1 7 1 13 1 15 1 35 1 5 1 35 1 35 1 3 1 19 1 38 1 38 1 3 1 3 1 39 1 5 1 36 Revised February 2004 TB200408 NO O O O PD S LI P P 1 8 2 11 18 2 11 18 2 1 11 3 16 11 T 6 2 amp 2 4 4 4 40 OPTION 8 11 10 5 13 5 4 1 5 14 30 31 1 3 2 OPTION 14 4 27 1 ALPHABETICAL INDEX mSS a CA 500 Series S M PARTS DESCRIPTION SUPPORT NO 247 SW REGULATOR 1505 12 SW REGULATOR 1 1505 24 SW REGULATOR LCA150S 24 XJCM SW REGULATOR 505 5 SYRINGE MOTOR ASSY SYRINGE MOTOR ASSY TABLE LOCK MECHANISM ASSY TABLE LOCK MECHANISM ASSY THERMAL SENSOR ASSY THERMAL SENSOR ASSY TIMING BELT B216MXL4 8 TIMING BELT B488MXL9 5 TOP PANEL DM0930 TRANSFORMER POWER ASSY 100V TRANSFORMER POWER ASSY 200V TRAP CHAMBER COMPLETE TRAP CHAMBER PROCEDURE TRASH COVER CA 500 TUBE SILICONE 1 5MMID X 6MMOD TUBE SILICONE 1 32 X3 32 F 7391
85. 0 Series S M 3 2 Revised December 2001 Detector Block Thermister PCB No 2133 LCD Mechanical THERMO U Pre Ample Heater Stop Switch ey Touch Screen PCB No 9258 SET IDE No 9258 9263 E LED2 LO Inverter VR N LED for Scattered LCD Contrast Volume S lt 2 m OR em Volumetric Unit Q z No 9259 Built in Pri LED1 uilt in Printer LEDforTransmitted PCB No 9258 SM 14 Syringe X Y Z Drive Mechanism PCB No 9260 5 2 9303
86. 1 3 A 1 37 A 1 19 A 1 19 A 1 38 A 1 38 A 1 38 A 1 23 A 1 17 A 1 15 A 1 23 A 1 21 A 1 7 A 1 33 A 1 19 A 1 36 A 1 39 A 1 36 A 1 39 Y Z gt a BIG RRA OA N O N A 7 5 N N B OO N m O N F o G m o 2 e c N O 8 Revised February 2004 TB200408 PART NO INDEX PART NO 346 4213 1 346 8215 2 348 3812 1 348 5082 5 348 5936 2 363 1597 8 363 2558 6 363 2559 0 363 5015 0 363 5015 0 363 5015 0 365 1333 3 365 1333 3 365 1333 3 365 2231 4 365 9200 4 369 8016 8 369 8016 8 369 8016 8 369 8016 8 369 8326 1 369 8326 1 369 8326 1 369 8326 1 369 8601 5 369 8601 5 369 8602 9 369 8602 9 369 8603 2 369 8603 2 369 8604 6 369 8604 6 424 4679 6 424 4679 6 424 4679 6 424 4679 6 424 9150 0 424 9151 3 426 3152 0 442 1403 8 442 1450 3 442 3307 4 442 3433 7 442 3509 2 442 4003 7 442 5279 4 442 5280 9 442 5290 6 442 5290 6 442 5292 3 442 5295 4 442 5305 4 442 5315 1 442 5416 1 442 5452 5 442 5452 5 CA 500 Series S M en PART DESCRIPTION O RING S 3 SLICONE SEAL TEFLON AR401 P3 XC SCREW BINDING M3X6 SUS SCREW HEX SOCKET BOLT M8X14 SU SCREW ROUND M3X15 STAY NO 11 HOLDER NO 89 HOLDER NO 90 TTO FIXING MATERIAL NO 15 PANEL L DM0931 FIXING MATERIAL NO 15 SUPPORT NO 247 SUPPO
87. 11 RE m A 8 6 4 1 X Axis Home Position Error a EU Uu PI deu 8 6 4 2 Y Axis Home Position Error ead Dt a rc 9 6 4 3 Z Axis Home Position Error 10 642 Z AxiSDO6SWIYUEIrIOIL u uuu 11 045 Tube Emor POSION 12 6 4 6 Tube Release Error 13 IS DEMSING o DELL 14 6 5 1 Sample Rack POSION 14 052 Samping Error Position LLULLU e iu Len eau a 15 6 5 3 Insufficient Reagent Holder No 16 094 INO IRSACUOMN 17 0 00 ee ene 18 50 19 057 20 er 9 2 EO RETE 21 6 6 1 Replace Sample 21 6 6 2 Setsample RACK 21 6 6 3 Replace Sample Rack Drawer 22 6 6
88. 11 A 1 35 A 1 11 A 1 35 A 1 13 A 1 35 A 1 9 A 1 35 A 1 5 A 1 5 A 1 3 A 1 31 A 1 31 A 1 31 A 1 31 A 1 3 A 1 35 2H 12 25 29 25 7 7 amp 1 3 amp 1 1 amp 2 amp 19 29 20 6 amp 22 23 NO 6 6 5 1 21 11 31 12 7 Revised February 2004 TB200408 PART NO INDEX PART NO 662 8182 0 662 8182 0 662 8214 1 8 662 8222 1 663 0158 8 663 0158 8 663 0159 1 663 0159 1 663 0160 6 663 0160 6 663 0161 0 663 0161 0 663 0162 3 663 0162 3 663 0163 7 663 0163 7 663 0164 1 663 0164 1 663 0165 4 663 0165 4 663 0166 8 663 0166 8 663 0167 1 663 0168 5 663 0168 5 663 0168 5 663 0169 9 663 0169 9 663 0170 3 663 0171 7 663 0171 7 663 0172 1 663 0173 4 663 0174 8 663 0175 1 663 0175 1 663 0176 5 663 0176 5 2 663 0177 9 663 0177 9 663 0179 6 663 0179 6 663 0180 1 663 0181 4 663 0181 4 663 0182 8 663 0183 1 663 0183 1 663 0184 5 663 0185 9 663 0185 9 663 0186 2 663 0186 2 663 0187 6 663 0187 6 663 0188 0 CA 500 Series S M x AN PART DESCRIPTION X AXIS WIRING CORD X AXIS WIRING CORD WIRING CORD PD DW0458 WIRING CORD PD SIGNAL DW0590 DETECTOR BLOCK AT3 DETECTOR BLOCK AT3 DETECTOR BLOCK STANDARD DETECTOR BLOCK STANDARD HEATER ASSY HEATER ASSY COOLING SECTION ASSY COOLING SECTION ASSY COOLER ASSY THERMAL MODULE COOLER ASSY COOLING FAN ASSY COOLING FAN ASSY VOLUMETRIC PISTON ASSY VOLUMETRIC PISTON ASSY SYRINGE
89. 2 Se 1 15058 5 av 3 AC100V AC100V 4 FUSE Y x 117V 100V Power Switch D 2 7 100V H 5 6 e 1 i ORG x x BLK ACT I6 5V 15 6 TEE Ts Yd X d x CA 500 Power Transformer 100V _ FG ceni 100V PE s J gt g20V 16 5V AC Inlet NET I FG LO Ra Figure 3 3 CA 500 Power Supply System Block Diagram Descriptions Switching Regulator LCA150S 24 XJCM DC 24 V Via PCB No 4086 used for X Y Z and Syringe Motor excitation power source for Built In Printer for inverter power source for LCD and for power source for Probe Heater CA 500 Series S M 3 4 Revised December 2001 g Switching Regulator LCA150S 12 12 V Via PCB No 4086 used for Detector Block heater Reagent Cooler Unit Peltier cooler Reagent Cooler Unit cooling fan Solenoid Valve drive and ID Motor drive Also used for Main Unit cooling fan with direct connection Switching Regulator LCA50S 5 1 DC 5 V Via PCB No 4086 used for Digital Circuit for each PC board Also used as the analog power source PCB No 6362 or PCB No 6373 for temperature control circuit CA 500 Transformer V AC100 V Used for driving Pressure Pump and Vacuum Pump Also connect
90. 203 376 3 Barcode Fixed po Position Tube 1 Tube 10 STAT CA 500 Series S M 5 24 Revised December 2001 g 5 11 2 Detector Block Adjustment Value Activation Method Detector well 1 4 Offset Target Value High Sensitivity 128 128 Low Sensitivit 139 128 Chromogenic Method Detector well 5 Offset Immunoassy Method Detector well 6 Offset 4000 5 11 3 Temperature Adjustment Value Unit MainValue Sub Cooler Unit Detector Block Pipette Section Room Temperature NOTE These are the displayed values when initialized For the Sub values refer to the values on the labels attached on each temperature control PCB in each unit For the Main values refer to the values labeled on the CPU board Refer to Section 4 4 Temperature Adjustment 5 11 4 Transmitted Light LED Adjustment Value Transmitted Light LED Calibration Adjustment Limit AD 3800 Change Limit CH5 DA Change Limit CH6 DA 60 5 11 5 Pressure Adjustment Value Offset NOTE These are the displayed values when initialized In case of initializing the EEPROM refer to the values labeled on the CPU board Refer to Section 4 1 Pressure Adjustment CA 500 Series S M 5 25 Revised December 2001 g 5 11 6 5 11 7 Service Setting Value 510 520 Pg Test Mode Value Anl Check Mode Rinse Wate Time Barcode Mod 7 Wash Test Mode ADC BUFF Vlin interim 5 11 8 SLD Vial 5 11 9 CA 500 Ser
91. 210 5 663 0408 8 663 0408 8 663 0403 0 663 0403 0 663 0406 1 663 0406 1 662 2221 6 662 2410 6 322 9150 1 324 9081 6 265 1241 4 265 1242 8 UNIT PAGE N N O O 114 a O 1 39 1 9 1 9 1 9 1 9 1 23 1 35 1 9 1 15 1 9 1 35 1 17 1 15 1 37 1 5 1 5 1 33 1 39 1 9 1 5 1 5 1 39 1 5 1 5 1 39 1 5 1 5 1 5 1 5 1 5 1 39 1 5 1 17 1 5 1 35 1 33 1 19 1 5 1 21 1 27 1 35 1 35 1 31 1 33 1 31 1 33 1 31 1 33 1 31 1 33 1 31 1 31 1 5 1 19 1 35 1 35 Revised February 2004 TB200408 NO 6 18 10 13 13 12 14 18 11 17 21 1 4 25 24 21 26 6 21 26 6 31 36 6 31 36 6 21 31 8 6 18 14 ALPHABETICAL INDEX PARTS DESCRIPTION WIRING CORD NO 2703 WIRING CORD PD DW0458 WIRING CORD PD SIGNAL DW0590 X AXIS MOTOR ASSY X AXIS MOTOR ASSY X AXIS SLIDER ASSY X AXIS SLIDER ASSY X AXIS WIRING CORD X AXIS WIRING CORD Y AXIS MOTOR ASSY Y AXIS MOTOR ASSY Z AXIS BASE ASSY Z AXIS MOTOR ASSY Z AXIS MOTOR ASSY Z1 SLIDER C ASSY DU1469 Z2 SLIDER C ASSY DU1468 ZSB REAR COVER CA 500 Series S M A 3 6 PART NO 265 1243 1 6
92. 232C protocol and time out CA 500 s Action Warning 1 Probable Cause 1 Failure of connection cable 2 Failure of host computer 3 Failure of PCB No 6362 2 Confirmation by The operator 1 Check the connection with host computer 2 Check the host computer 3 Confirmation by Service Engineer 1 Replace the PCB No 6362 CA 500 Series S M 6 32 Revised December 2001 8 6 9 9 Time Out 6 9 10 HC STX Time Out 6 9 11 HC ETX Time Out Monitor Timing During data transmission Monitor Method Monitors RS 232C protocol and time out CA 500 s Action Warning 1 Probable Cause 1 Failure of connection cable 2 Failure of host computer 3 Failure of PCB No 6362 2 Confirmation by the operator 1 Check the connection with host computer 2 Check the host computer 3 Confirmation by Service Engineer 1 Replace the PCB No 6362 6 9 12 Instruction Not Found in HC Monitor Timing During data transmission Monitor Method Monitoring RS 232C protocol and time out CA 500 s Action Warning 1 Probable Cause 1 No registration of Work List 2 Confirmation by the operator 1 Register the Work List in the host computer correctly 3 Confirmation by Service Engineer The same as above 2 6 9 13 Serial Illegal Error Monitor Timing During data transmission Monitor Method Monitoring RS 232C protocol and time out CA 500 s Action Warning 1 Probable Cause 1 Receive Data failure caused by noise etc 2 Prob
93. 3 Confirmation by Service Engineer 1 If the warning is displayed in the normal status replace the syringe 2 other case the PCB 6362 might be faulty CA 500 Series S M 6 20 Revised December 2001 g 6 6 SAMPLER ERRORS 6 6 1 Replace Sample Rack Monitor Timing Monitor every 50 msec during interruption Monitor Method The micro switch in the sample rack table CA 500 s Action Warning at each analysis 1 Probable Cause The sampler rack is removed 2 The sampler rack is not properly mounted 3 Failure of sampler rack sensor assembly 4 Failure of wiring cord wiring cord with spiral 5 Failure of PCB No 6362 2 Confirmation by the operator 1 Place the sampler rack properly 3 Confirmation by Service Engineer 1 Check the dirt on sample rack table and or it is free of foreign matters 2 Short circuit the pin 20 and pin 18 of relay connector If it can be monitored on the switch sensor screen the sample rack drawer might be faulty Check the harness and sample rack sensor If the above step 2 does not solve the trouble short circuit the pin 14 and 12 of CN111 on PCB No 6362 If this solves the trouble the wiring cord wiring cord with spiral is faulty If not the PCB No 6362 is faulty 6 6 2 Set Sample Rack Monitor Timing When starting analysis Monitor Method The micro switch in the sample rack table CA 500 s Action Warning is displayed and no analysis is performed 1 Probabl
94. 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 31 1 13 1 5 1 29 1 5 1 5 1 21 1 29 1 5 1 5 1 5 1 39 1 5 1 5 1 39 1 5 1 5 1 5 1 5 Revised February 2004 TB200408 NO 3 13 11 10 5 4 OPTION OPTION 3 3 3 27 1 1 13 6 16 26 36 4 5 14 15 15 24 34 25 35 14 17 PART NO INDEX PART NO 442 5475 1 442 5475 1 443 0823 8 443 0823 8 443 0823 8B 443 2804 4 443 2804 4 443 2804 4 461 2047 Z 461 2655 0 461 9128 7 541 1352 1 662 0168 8 662 0217 3 662 0218 7 662 0219 1 662 0220 5 662 0221 9 662 0222 2 662 0223 6 662 0224 0 662 0225 3 662 0228 4 662 0228 4 662 0276 3 662 0278 1 662 0279 4 662 0280 9 662 0281 2 662 0282 6 662 0283 0 662 0284 3 662 0285 7 662 0286 1 662 0287 4 662 0288 8 662 0289 1 662 2203 9 662 2203 9 662 2204 2 662 2204 2 662 2205 6 662 2205 6 662 2206 0 662 2206 0 662 2207 3 662 2207 3 662 2208 7 662 2209 1 662 2219 8 662 2220 2 662 2221 6 8 662 2409 1 8 662 2410 6 662 8181 6 662 8181 6 CA 500 Series S M 5 Flirt PART DESCRIPTION TUBE TOALONE 3MMID X 6MMOD TUBE TOALONE 3MMID X 6MMOD CHAMBER NO 4 CHAMBER NO 4 CHAMBER NO 4 NON RETURN VALVE MFP 6 V NON RETURN VALVE MFP 6 V NON RETURN VA
95. 4 5 6 11 r A 3 Press set key 0 _ Enter Set l C Quit Enter a target value Enter an indicated value 100 999 which is given in the calibrators table of assigned values for calibration using the numeric keys and press Enter key Select a container of the calibrator for calibration Move the cursor to Vial Type using 1 and keys and press Next key to select the container Set the calibrator for calibration to the reagent holder 1 and set CA CLEAN to the reagent holder 11 Press Set OK keys to start LED calibration When the operation is completed the LED Calibration Update Confirmation screen will appear Ready IP Replace Rack YES LED Calibration Update Confirmation Sysmex CH1 CH2 CH3 CH4 45 130 22 130 2 OK OK ERR1 OK Too weak to use CH3 A Weak but still available CH1 Please refer to Operator s Manual Set Cancel Displayed contents 1 Channel No 2 LED status 3 OK Available OK Available However replacement is required within a few months ERRxx Not available When updating a new adjustment value press FIX key When the status of all channels is OK The new adjustment value is saved and returns to the LED Calibration screen When there is a channel with a calibration error The confirmation screen will appear Press Cancel key to return to the LED Calibration Update Confirmation screen
96. 4 Barcode Scanner Driver Error 23 6 6 55 Barcode Scanner Error a ara od Gin FE cusa 23 6660 Change Sample 24 25 6 6 8 Exist same Sample NO 26 6 6 9 Load New 26 ADAD au ee eee 27 o An 27 6 7 2 Check Reagent Expiry 28 28 ENO u uui m 29 29 og OO Data uu 29 050 u o m saus 29 CA 500 Series S M Revised December 2001 g 6 9 F xIernal Device EITO S u uuu RUFI 30 DOP uui makana 30 DOS PAUMO ENON tenes 31 An 31 6 9 4 Communication Error diet 32 Te hhi C il u 32 6 0 eee ee ee 32 6 9 7 Transmission Count Error 1 onera nep ena semet GEN PAR RR 32 0 9 6 HC Reception Count Error 32 099 HCACK TING 33 SRT gt E 33 O
97. 5 11 13 Quality Control Setting Value a All parameters CA 500 Series S M 5 33 Revised December 2001 g LOO 9 W S 009 95 oj oj 9 o o 3 uomeidjeo C D T3 T EET TU E LU TET TU a Tr so 0 0 0 so so so 50 so so 50 WebEsHioui so so so 0 so so so so 50 so so 50 or O o o o O o o o o o o o o o o o o 340 33O 330 340 340 340 40 34O 30 340 a30 sss 9 s s S 9 s S 5 s 340 340 340 440 440 440 44O 30 0 30 ATHVA ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ooz ones e e 8 8 8 wm 340 340 430 340 340 440 a30 440 40 34O 34O 340 0 d40 oor oor oor oor oor oor oor oor oor oor oor oor oor oor oor oor oo
98. 6 CAUTION MARK NO 208 CAUTION MARK NO 208 CAUTION MARK NO 208 CAUTION MARK NO 208 CH6 CHAMBER NO 4 CHAMBER NO 4 CHAMBER NO 4 CHROMOGENIC LED ASSY CHROMOGENIC LED ASSY COAGULATION LED ASSY COAGULATION LED ASSY CONNECTING TUBE NO 3 CONNECTING TUBE NO 50 COOLER ASSY COOLER ASSY THERMAL MODULE COOLER THERMAL ASSY COOLER THERMAL ASSY SERNSOR IC COOLING FAN ASSY COOLING FAN ASSY COOLING SECTION ASSY COOLING SECTION ASSY COVER SENSOR SHUTTER B DM1374 CYLINDER ASSY CYLINDER ASSY D DIMER LED ASSY 575NM D DIMER LED ASSY 800NM DETECTOR BLOCK AT3 DETECTOR BLOCK AT3 DETECTOR BLOCK D DIMER 800NM DETECTOR BLOCK D DIMER 800 DETECTOR BLOCK D DIMER 3 1 663 0195 6 264 0801 7 663 0374 9 289 9169 1 289 9170 6 289 9170 6 663 0410 6 663 0411 0 663 0412 3 663 0413 7 424 9150 0 424 9151 3 324 9082 0 031 0171 4 324 9078 4 324 9076 7 663 0188 0 663 0188 0 369 8016 8 369 8016 8 369 8016 8 369 8016 8 369 8326 1 369 8326 1 369 8326 1 369 8326 1 663 0404 3 443 0823 8 443 0823 8 443 0823 8B 662 2204 2 662 2204 2 662 2205 6 662 2205 6 442 1403 8 442 1450 3 663 0162 3 663 0162 3 662 2206 0 662 2206 0 663 0163 7 663 0163 7 663 0161 0 663 0161 0 324 9075 3 663 0166 8 663 0166 8 662 0280 9 662 0279 4 663 0158 8 663 0158 8 663 0415 4 663 0415 4 663 0399 1 UNIT PAGE 2 2 AA n gt gt gt gt lI lI
99. 62 8214 1 662 8222 1 663 0201 1 663 0201 1 663 0181 4 663 0181 4 662 8182 0 662 8182 0 663 0185 9 663 0185 9 663 0182 8 663 0186 2 663 0186 2 663 0393 0 663 0394 3 322 9152 9 UNIT PAGE I lI lI lI lI 5 lI lI A 1 35 A 1 11 A 1 35 A 1 9 A 1 35 A 1 7 A 1 15 A 1 9 A 1 35 A 1 15 A 1 35 A 1 17 A 1 17 A 1 35 A 1 17 A 1 17 A 1 17 NO 11 10 34 6 13 3 11 11 12 11 15 1 3 16 10 11 12 Revised February 2004 TB200408 PART NO INDEX RIR SIA SA HOMME Am PART NO 021 0011 0 031 0171 4 228 3418 6 228 3753 3 228 3753 3 228 3754 7 228 3754 7 228 4050 8 228 0153 2 228 9153 2 264 0801 7 265 1241 4 265 1242 8 265 1243 1 266 3533 5 266 3536 6 266 5045 0 266 5106 0 266 5293 0 266 5395 2 281 7226 1 289 9169 1 289 9170 6 289 9170 6 289 9376 9 289 937 7 2 289 9378 6 289 9379 0 322 9150 1 322 9151 5 322 9152 9 324 9075 3 324 9076 7 324 907 17 1 324 9078 4 324 9079 8 324 9080 2 324 9081 6 324 9082 0 324 9083 3 324 9084 7 324 9085 1 342 1517 1 342 1815 1 342 1816 4 342 2776 6 343 2466 0 344 3529 8 344 5471 7 345 3767 8 346 3909 0 346 3909 0 346 3939 1 346 3939 1 500 Series S M PART DESCRIPTION CA 500 PRESSURE CHAMBER ASSY BOLT M8X10 PRESSURE CHAMBER KIT CA 5H CA 5H Z AXIS POSITION ADJUSTMENT TOOL PM PHOTO SENSOR EE SX670 PHOTO INTERRUPTER LG 217D 3 PHOTO INTERRUPTER LG 217D 3 LCD LRHBJ3431A LCD LRHBJ3431A PHOTO IC SENSOR
100. 63 0188 0 345 3767 8 663 0187 6 346 4213 1 324 9077 1 324 9082 0 324 9081 6 2 663 0183 1 663 0184 5 663 0190 8 CA 500 Series S M Drawing Description CATCHER ASSY SPRING PIN KSSC 2017 MIXER MOTOR ASSY O RING S 3 SLICONE VIBRATION ARM DM1163 C ARM PLATE DM1221 WIRING CORD HOLDER DM1220 PIPETTE HOLDER ASSY PIPETTE CRUSH SENSOR ASSY PIPETTE ASSY CA 500 A 1 19 Revised December 2001 8 CA 500 Volumetric Piston Assy ere E usss mm CA 500 Series S M Revised December 2001 8 1 20 VALUMETRIC POSTON ASSY 8 500 CYLINDER ASSY Code No Drawing Description 663 0164 1 1 VOLUMETRIC PISTONASSY 1 663 0166 8 1 CYLINDER ASSY 663 0167 1 2 PISTON ASSY 663 0166 8 11 CYLINDER ASSY 442 3509 2 11 NIPPLE NO 9 343 2466 0 12 O RING NO 16 346 8215 2 13 SEAL TEFLON AR401 P3 XC CA 500 Series S M 1 21 Revised December 2001 8 CA 500 Volumetric Mech Assy Revised December 2001 8 1 22 CA 500 Series S M CA 500 Volumetric Mech Assy Code No Drawing Description Qty per No Unit 663 0165 4 1 SYRINGE MOTOR ASSY 1 228 3753 3 2 PHOTO INTERRUPTER LG 217D 3 1 342 1517 1 3 PULLEY NO 185 1 342 2776 6 4 PULLEY NO 143 1 CA 500 Series S M A 1 23 Revised December 2001 8 500 Operation Panel Assy 1 2 CA 500 Series S M A 1 24 Revised June 2003 ECR303C033 500 Operation Pane
101. 663 0184 5 A 4 PIPETTE CRUSH SENSOR ASSY 1 913 1091 3 5 STANDARD SCATTERING STICK SET 1 CLASS B 424 9150 0 B 1 BOTTLE TANK A RINSE BLUE 1 424 9151 3 B 2 BOTTLE WASTE RED 1 424 4679 6 3 LID NO 9 5 663 0190 8 B 4 PIPETTE ASSY 1 346 8215 2 B 5 SEAL TEFLON AR401 P3 XC 1 663 0198 7 B 6 SOLENOID VALVE ASSY VOLUMET 1 lt CLASS C gt 663 0197 3 C 1 VACUUM PUMP ASSY 1 663 0191 1 C 2 PRESSURE PUMP ASSY 1 289 9377 2 3 SW REGULATOR LCA150S 12 1 289 9378 6 C 4 SW REGULATOR LCA150S 24 XJCM 1 289 9376 9 C 5 SW REGULATOR LCA50S 5 1 PCB used with CA 550 560 upper compatible and will be replaced with the old PCB written above when the stock is depleted CA 500 Series S M A 2 1 Revised December 2001 ALPHABETICAL INDEX 11 gt gt CA 500 Series S M PARTS DESCRIPTION AC INLET ASSY ADAPTOR ID 23 G BASE DM1197B BATTERY LITHIUM CR17450SE 2 CJ2 BATTERY LITHIUM CR23500SE CJ2 BATTERY LITHIUM CR23500SE CJ2 BOLT 8 10 BOTTLE TANK RINSE 5L BLUE BOTTLE TANK RINSE 5L BLUE EU UK BOTTLE TANK WASTE 5L RED BOTTLE TANK WASTE 5L RED EU UK BOTTLE TANK A RINSE 2L BLUE BOTTLE TANK A WASTE 2L RED C ARM PLATE DM1221 CA 500 PRESSURE CHAMBER ASSY CA 5H Z AXIS POSITION ADJUSTMENT TOOL PM CATCH BOX DM1357 CATCH HOLD PLATE DM1358 CATCHER ASSY CATCHER ASSY CAUTION MARK NO 16 CAUTION MARK NO 16 CAUTION MARK NO 16 CAUTION MARK NO 1
102. 89 HOLDER NO 90 TTO HYDRAULIC CONNECTOR NO 23 ID ASSY ID ASSY ID MOTOR ASSY ID MOTOR ASSY ID WIRING CORD ID WIRING CORD INSTRUCTION LABEL 1 JAPANESE INSTRUCTION LABEL 1 JAPANESE INSTRUCTION LABEL 2 INSTRUCTION LABEL 2 INSTRUCTION LABEL 3 JAPANESE INSTRUCTION LABEL 3 JAPANESE INSTRUCTION LABEL 7 INSTRUCTION LABEL 7 INVERTER CXA K05M C INVERTER INV 5 LCD LRHBJ3431A LCD LRHBJ3431A LID NO 9 LID NO 9 LID NO 9 LID NO 9 LIGHT SHIELD COVER ASSY LIGHT SHIELD COVER ASSY IMMUNO LOCK SPRING DM1298 MAIN UNIT FAN ASSY MAIN UNIT FAN ASSY MIXER MOTOR ASSY MIXER MOTOR ASSY NIPPLE NO 9 A 3 2 PART NO 663 0399 1 663 0159 1 663 0159 1 662 2203 9 662 2203 9 663 0180 1 663 0171 7 663 0171 7 664 0167 9 664 0167 9 363 5015 0 363 5015 0 344 5471 7 266 5045 0 266 5293 0 266 5106 0 266 3533 5 266 3536 6 266 5395 2 663 0372 1 663 0160 6 663 0160 6 344 3529 8 363 2558 6 363 2559 0 442 3433 7 663 0177 9 663 0177 9 663 0176 5 663 0176 5 662 8181 6 662 8181 6 369 8601 5 369 8601 5 369 8602 9 369 8602 9 369 8603 2 369 8603 2 369 8604 6 369 8604 6 228 9153 2 228 9153 2 228 3754 7 228 3754 7 424 4679 6 424 4679 6 424 4679 6 424 4679 6 663 0204 2 663 0401 2 324 9083 3 663 0196 0 663 0196 0 663 0187 6 663 0187 6 442 3509 2 UNIT PAGE PpP O UNSALABLE UNSALABLE 1 1 UNSALABLE UNSALABLE 1
103. 9 wash i Adjustment CAUTION 19 i Adjustment In Basic Position Adjustment mode the value of the probe rinse cup inside is calculated automatically from the setting value of the probe rinse cup outside It will be stored in the memory when Mecha Position adjustment is completed In Fine Adjustment mode set the value of the probe rinse cup inside by selecting Enter Pulses key Probe Rinse Cup Inside Value 9 washisetingvalue Same as Probe Rinse Cup Outside Value Probe Rinse Cup Outside Value 200 Same as Probe Rinse Cup Outside Value CA 500 Series S M 4 20 Revised December 2001 4 3 8 Position Adjustment Procedure of Pipette 1 tube 1 Adjustment Parameter Pipette Position XYZ Summary Use the sample tube with 50 uL of distilled water inside for the position adjustment of the reaction tube rack Adjust 3 positions for each two separated reaction tube rack otandard XY direction The center of each sample tube set into the adjustment position of the reaction tube rack Z direction The lowest point of the pipette descended to the sample tube with 50 uL of the distilled water inside of each adjustment position of the reaction tube rack 1 XY Adjustment 1 Place 50 pL of distilled water into the reaction tube and set it into the tube No 1 of the reaction tube rack Figure 4 3 15 Reaction Tube with 50 pL Distilled Water 2 Verify that the 11 p tube 1 is shown on the lef
104. AY DPO2COSB 9703 Figure 3 21 PCB No 9265 Assembly Drawing CA 500 Series S M 3 26 Revised December 2001 SECTION 4 ADJUSTMENT To Cover 4 1 4 2 4 3 4 4 4 5 cde coe deta sated 1 4 1 1 Adjustment of Pressure Detector 1 4 1 2 X Adjustment of Pressure nnns 3 Detector Block Sensitivity Adjustment nnn nennen nnne nns 4 4 2 1 Required Tools for 4 4 2 2 gt Overview of Adjustment Screen 4 4 2 3 Adjustment of Detector Well for analyzing the scattered light 6 4 2 4 X Adjustment of Detector Well for analyzing the transmitted light Chromogenic and nnn nnn 8 9 4 2 6 Target Value List for Adjustment 9 Mechanical System 10 4 3 1 Required Tools TOF AGQ USIImIOliL E snb 10 4 3 2 How to Enter the Mechanical System Position Adjustment Mode 10 4 33 Mechanical System Position Adjustmen
105. CA 500 Series S M 6 9 Revised December 2001 8 6 4 3 Z Axis Home Error Monitor Timing At time of home position sensing during operation Monitor Method The photo interrupter shades the light of Z axis drive mechanism CA 500 s Action Emergency stop 1 Probable Cause 1 Drive mechanism operation is obstructed 2 Loosened pulley of motor 3 Failure of PCB 9264 4 Failure of PCB No 2134 5 Defective light shield 6 Flaws on shaft 7 Failure on bushing 8 Failure of PCB 9260 9 Failure of X axis wiring cord 10 Failure of PCB No 6362 11 Failure of Z axis motor assembly 12 Failure of PCB No 4086 2 Confirmation by the Operator 1 Remove the obstruction in Z axis drive mechanism 2 Turn off the power supply and turn it on again 3 Confirmation by Service Engineer 1 Retighten the screw of the pulley of motor 2 If home position cannot be detected even when the drive mechanism is operated a Check whether the light shield is defective or not Suspect Part Test Points Expected Value Position sensor CN1 PCB No 9264 pin 9 GND and pin 7 5 V gt 0 V when the sensor is shielded CN4 PCB No 2134 pin 9 GND and pin 7 5 V gt 0 V when the sensor is shielded CN1 PCB No 2134 pin 17 and pin 18 GND shielded CN1 PCB No 9260 pin 17 and pin 18 GND shielded CN105 PCB No 6332 pin 7 and pin 14 GND shielded 3 When the motor does not operate a Any of motor PCB No 9264 PCB N
106. CB No 2156 PD2 2157 Y Z RELAY2 Y Axis Home Position Sensor PCB No 6375 PRCN 3 BENE 1 PCB No 6373 MAIN 2 8 PCBNO 9258 X LED2 LED for analyzing scattered 9 PCBNo 9259 LEDI _ LED for analyzing transmitted light LCD Contrast Volume Z Axis Relay Z Axis Home Position Sensor PCB No 9265 PR RELAY Operation Panel Syringe Motor SV Relay PCB No 9303 PR RELAY2 NOTE PCB No indicated with is added with CA 550 560 which is upper compatible CA 500 Series S M 3 1 Revised December 2001 3 2 Block Diagram and Power Source 3 2 1 Electric Block Diagram Detector Block
107. CK SENSOR ASSY ID WIRING CORD ID MOTOR ASSY ID ASSY MAIN UNIT FAN ASSY WIRING CORD NO 2703 X AXIS WIRING CORD X AXIS MOTOR ASSY WIRING CORD NO 2702 Y AXIS MOTOR ASSY Z AXIS MOTOR ASSY PIPETTE ASSY CA 500 WIRING CORD NO 2701 MIXER MOTOR ASSY DETECTOR THERMAL ASSY HEATER ASSY CHROMOGENIC LED ASSY COAGULATION LED ASSY WASTE BOTTLE ASSY VR ASSY EMERGENCY STOP SW ASSY BATTERY LITHIUM CR23500SE CJ2 SYRINGE MOTOR ASSY PRESSURE PUMP ASSY SOLENOID VALVE ASSY VOLUMET SOLENOID VALVE NO 14D PM VACUUM PUMP ASSY RINSE BOTTLE ASSY CA 500 WIRING CORD PD SIGNAL DW0590 A 1 35 IL I IX lI l3 I l3 l3 l3 I l l3 l3 I l3 l3 lI lI l3 ll Revised December 2001 8 CA 500 Pressure Chamber Assy Code No Drawing Description NO 365 1333 3 1 3 SUPPORTNO247 4 443 0823 8B 2 CHAMBER NO 4 363 5015 0 3 FIXING MATERIAL NO 15 346 3939 1 4 O RING P 39 5 BOLT M8X10 346 3909 0 6 O RING P 8 NITRIL CA 500 Series S M A 1 36 Revised December 2001 8 500 5 Drawing Description Qty per m VU ME 663 0373 5 1 TOP PANEL DM0930 1 663 0375 2 2 PANEL R DM0932 1 363 5015 0 3 PANEL L DM0931 1 324 9080 2 4 PANEL DM0933 1 500 Series S M A 1 37 Revised December 2001 8 CA 500 Sampler resa II OS M t Ma 2 e T
108. D 575NM PCB NO 2156 STANDARD CLOT AT3 PCB NO 2157 PCB NO 4086 PCB NO 6362 PCB NO 6373 PCB NO 7015 PCB NO 7015 2 FLASH MEMORY PCB NO 9260 PCB NO 9264 PCB NO 9265 PCB NO 9265 PCB NO 9303 PHOTO SENSOR EE SX670 PHOTO IC SENSOR PS R11L PHOTO INTERRUPTER LG 217D 3 PHOTO INTERRUPTER LG 217D 3 PIPETTE ASSY CA 500 PIPETTE ASSY CA 500 PIPETTE CRUSH SENSOR ASSY PIPETTE HOLDER ASSY PIPETTE HOLDER ASSY PISTON ASSY POWER SWITCH ASSY CA 500 PRESSURE CHAMBER KIT CA 5H PRESSURE PUMP ASSY PRESSURE PUMP ASSY A 3 3 PART NO 442 4003 7 443 2804 4 443 2804 4 443 2804 4 663 0168 5 663 0168 5 663 0168 5 663 0170 3 461 2047 7 461 2655 0 343 2466 0 346 3909 0 346 3939 1 346 3939 1 346 3909 0 346 4213 1 363 5015 0 663 0375 2 921 0351 8 662 0168 8 662 0276 3 662 0288 8 662 0218 7 662 0219 1 662 0217 3 662 0223 6 662 0282 6 662 0283 0 662 0284 3 662 0285 7 662 0281 2 662 0286 1 662 0220 5 662 0221 9 662 0287 4 662 0225 3 662 0278 1 662 0224 0 662 0222 2 662 0228 4 662 0228 4 662 0289 1 228 3418 6 228 4050 8 228 3753 3 228 3753 3 663 0190 8 663 0190 8 663 0184 5 663 0183 1 663 0183 1 663 0167 1 662 2219 8 021 0011 0 663 0191 1 663 0191 1 UNIT PAGE O O o A A Aana 1 29 1 31 1 31 1 39 1 3 1 25 1 27 1
109. Detector Block After 30 minutes since turning power ON of CA 500 perform the following procedures 1 Pour 150 pL of distilled water into two reaction tubes and put it into detection well CH5 and incubation well 6 2 Measure temperature of the water and confirm that temperature is within the following range Detection Well CH5 37 0 0 5 Incubation Well 6 37 0 1 0 Measure temperature after temperature of the water becomes stable 4 4 2 3 Reagent Nozzle Perform the temperature adjustment for reagent nozzle after the temperature adjustments of the detector block and reagent block are passed successfully 1 Enter the service mode and select Special Operate gt Service gt Adjust gt Temp Control 2 Press Nozzle area and input the D A value attached on the heated probe to S xxx area 3 To verify the Temperature refer to Section 5 5 4 Reagent Temp for the procedures Jump to Section 5 5 4 4 4 2 4 Room Temperature 1 Enter the service mode and select Special Operate gt Service gt Adjust gt Temp Control 2 Verify that the room temperature by thermometer is within the displayed temperature 3 C 3 Press Return key to finish the confirmation CA 500 Series S M 4 30 Revised February 2004 TB200408 4 4 3 Temperature Adjustment Procedures To adjust the temperature at each temperature controlled unit follow the steps below 1 Measure the actual temperature of the unit by referrin
110. Dilute Ratio ON OFF OFF OFF OFF OFF OFF OFF CA 500 Series S M 5 35 Revised December 2001 g 5 12 SETTINGS OF CA 500 WITH 800NM DETECTOR When settings of CA 500 with 800nm detector are initialized the settings of CA 500 with 575nm detector are applied Therefore following settings must be changed to recover it 1 Service setting 1 Press Special Menu Special Operate Service Service Setting Change parameters in Service Setting screen as follows Wavelength 800nm D Dimer Init for LPIA DD PFDP OFF 2 Press Return Fix to save parameters 3 Press Service Initial Init Entire Memory to enable the setting 2 Gain calibration 1 Press Special Menu Special Operate Service Adjust Detector Gain 2 Press Channel Change and select Channel 6 3 Press GAIN CALI and move the cursor to High Gain of 800nm and change the value 0 40 4 Press Enter Quit Fix to save parameters 3 Reagent Holder setting 1 Press Special Menu Settings Analysis Settings Reagent Holder The Reagent Holder Setting screen will appear 2 Press Change Group key and select Group 3 3 Move the cursor to Reagname pos 1 and press Select Reagent The screen for selecting a reagent will appear Move the cursor to AT3Reag and press Select 4 Move the cursor to Reagname pos 2 and press Select Reagent The screen for selecting a reagent will appear Move the cursor to TestThr and press Se
111. Down Adjustment Screen Set Key Use to execute Descend Pulse Adjustment screen Cancel Key Cancels the Z Pulse Down Adjustment and returns to the Reagent Vial Settings screen lt Z Pulse Down Adjustment gt Fill the dead volume of the reagent in the reagent vial and place at the reagent holder No 9 Press Set key to execute Z Pulse Down Adjustment The probe moves to the reagent holder No 9 and detect a liquid surface for 5 times The difference between the average of the descend pulse and the value of the reagent holder No 9 position adjustment will be calculated as the pulse correction value 7 1 2 4 500 Series S M 5 20 Revised December 2001 g 5 9 OUTPUT OF SERVICE SETTINGS 1 Press Special Operate gt Service gt Print Service Set keys then the following screen will be displayed Ready IP Replace Rack YES Print Service Set oysmex Service Setting Flag Threshold Test Mode Reag Vial Settings Return Figure 5 9 1 Print Service Setting Screen Service Setting Key Use to output the service setting values Flag Threshold Key Use to output the flag threshold values for every tests Test Mode Key Use to output the test mode values Reag Vial Settings Key Use to output the reagent vial setting values Return or Quit Key Quits to output service settings and returns
112. ECTOR BLOCK D DIMER 800NM 1 322 9151 5 5 500 1 663 0201 1 6 X AXIS MOTOR ASSY 1 662 0220 5 7 4086 1 289 9377 2 8 SW REGULATOR LCA150S 12 1 289 9376 9 9 SW REGULATOR LCA50S 5 1 289 9379 0 10 SW REGULATOR 1505 24 1 662 8182 0 11 X AXIS WIRING CORD 1 662 0224 0 12 PCB NO 9260 1 662 2207 3 13 THERMAL SENSOR ASSY 1 530 540 510 520 amp 550 560 amp amp CA 550 CA 560 800nm detector block CA 500 Series S M A 1 9 Revised October 2003 ECR303G037 500 Detector Block Revised December 2001 8 1 10 CA 500 Series S M CA 500 Detector Block 8 Code No Drawing Description SIS lxi 663 0159 1 663 0158 8 663 0399 1 663 0415 4 662 0217 3 662 0281 2 662 0285 7 662 0284 3 662 2205 6 662 0218 7 662 0282 6 662 0219 1 662 0283 0 662 2203 9 663 0160 6 662 2204 2 662 0280 9 662 0279 4 663 0404 3 266 5395 2 662 8214 1 PCB used with 550 560 upper compatible and will be replaced with the old PCB written 3 3 amp 4 5 6 8 78 7 8 amp 9 10 510 520 530 540 550 560 CA 550 560 800 detector block PCB
113. ENSOR ASSY SAMPLE RACK SENSOR ASSY SAMPLE STAGE ASSY SAMPLE STAGE ASSY 2 IMMUNO SAMPLE TABLE ASSY ID SAMPLE TABLE ASSY STANDARD SAMPLE TABLE BASE ASSY SAMPLE TABLE BASE ASSY SAMPLE TUBE SPACER 10MM DIAMET SAMPLE TUBE SPACER 13 PHI SCREW BINDING M3X6 SUS SCREW HEX SOCKET BOLT M8X14 SU SCREW ROUND 15 SEAL TEFLON AR401 P3 XC SHAFT B DM1090B SILICONE GREASE THERMAL 800 8 SOLENOID ASSY SOLENOID ASSY SOLENOID VALVE ASSY VOLUMET SOLENOID VALVE ASSY VOLUMET SOLENOID VALVE NO 14D PM SPACER FOR RUBBER SHOE SPRING PIN KSSC 2017 SS ACTIARM DM1362 SS BASE PLATE DM1361 STANDARD SCATTERING STICK SET STAY DM1102 STAY NO 11 SUPPORT NO 247 SUPPORT NO 247 A 3 4 PART NO 663 01 72 1 663 0205 6 281 7226 1 663 0370 4 663 0392 6 342 2776 6 342 151 7 1 541 1352 1 663 0207 3 663 0206 0 663 0202 5 324 9080 2 663 0209 1 663 0209 1 663 0209 1 663 0407 4 663 0407 4 663 0402 6 663 0402 6 663 0405 7 663 0405 7 662 2220 2 662 2409 1 663 0199 1 442 3307 4 833 3895 6 663 0179 6 663 0179 6 663 0203 9 663 0400 9 663 0174 8 663 0173 4 663 0175 1 663 0175 1 663 0212 2 663 0213 6 348 3812 1 348 5082 5 348 5936 2 346 8215 2 663 0371 8 426 3152 0 663 0200 8 663 0200 8 663 0198 7 663 0198 7 941 0131 3 365 9200 4 345 3767 8 324 9085 1 324 9084 7 913 1091 3 324 9079 8 363 1597 8 365 1333 3 365 1333 3 UNIT PAGE gt lI 5 10
114. Function This PCB is the CA 500 program memory card storing the CPU program of PCB No 6362 MAIN When this PCB is inserted into the 68 pin card slot CN102 on PCB No 6362 or PCB No 6373 the operation becomes available On this memory card the flash memory is directly connected to the connector of the card This is not a PC card therefore do not insert it to the card slot on the instrument other than CA 500 Setting and Adjustment Setting and adjustments are not necessary LED and Test Point There are no LEDs or test point 3 10 PCB 9258 LED2 LED for scattered light 3 10 1 Function This PC Board is the board for mounting the LED for analyzing the scattered light in the Detector Block Two LEDs are mounted and two boards are used for four channels These LEDs are driven in the constant current driving circuit 20 mA on PCB No 6362 MAIN or PCB No 6373 MAIN 2 together with the LED for the transmitted light 3 10 2 Setting and Adjustment Setting and adjustments are not necessary 3 10 3 LED and Test Point There are no LEDs or test point CA 500 Series S M 3 23 Revised December 2001 3 11 PCB 9259 LED1 LED for transmitted light 3 11 4 Function This PC Board is the board for mounting the LED for the transmitted light in the Detector Block This LED is driven in the constant current driving circuit 20 mA on PCB No 6362 MAIN or PCB No 6373 MAIN 2 together with the LED for the scattered
115. INT i 1100 a Constant rone lt lt Circuit lt gt gt Thermister 1 Voltage PIO Hor for Thermistor 4 5 CLOCK AMP Ld LL Comparator d G 3 A D L L rs 01 CPU PIO cooler unit AMPX3 K RESET Thermister IC detector block 8 5 room temp SS PCB No 4086 cooler heater probe heater contro Interface PS Figure 3 13 Temperature Control Circuit 18 Pressure Control Circuit 00518 517 516 519 520 521 This circuit controls the pressure to supply water to each unit from Rinse Bottle This circuit is composed by the pressure sensor the differential amplifier the Offset circuit and the Comparator circuit and the pressure pump is controlled by these signals The pressure is supplied from the pressure pump to the pressure sensor 0518 mounted on the board and the sensor signals are output in accordance with the supplied pressure The Gain controlled value and the Offset controlled value are added on this signal by the differential amplifier and the signal is input in the comparator circuit U516 to compare the voltage with the specified one In the case the pressure decreases in this circuit the signal activating the pressure pump is output The other comparator circuit and the latch circuit U519 520 521 are used for detecting the pr
116. LE ASSY TRAP CHAMBER COMPLETE SAMPLE TUBE SPACER 10MM DIAMET SAMPLE TUBE SPACER 13 PHI TABLE LOCK MECHANISM ASSY TABLE LOCK MECHANISM ASSY PULLEY 1329A SHAFT B DM1090B HEAT SINK DM1113 TOP PANEL DM0930 BASE DM1197B PANEL R DM0932 PULLEY DM1329 Z1 SLIDER C ASSY DU1469 Z2 SLIDER C ASSY DU1468 DETECTOR BLOCK D DIMER DETECTOR BLOCK D DIMER SAMPLE STAGE ASSY 2 IMMUNO LIGHT SHIELD COVER ASSY IMMUNO RINSE BOTTLE ASSY CA 5H 5L RINSE BOTTLE ASSY CA 5H 5L WASTE BOTTLE ASSY 5 5L WASTE BOTTLE ASSY CA 5H 5L CH6 RINSE BOTTLE ASSY CA 5H BL EU UK RINSE BOTTLE ASSY CA 5H BL EU UK WASTE BOTTLE ASSY CA 5H 5L EU UK A 4 5 UNIT Q TY gt gt gt lI gt 35 lI gt I lI I lI I y lI I lI lI lI lI lI lI lI lI lI lI lI lI lI lI lI lI l3 lI lI lI lI gt x e PAGE A 1 19 A 1 17 A 1 19 A 1 35 A 1 5 A 1 35 A 1 5 A 1 5 A 1 35 A 1 5 A 1 35 A 1 5 A 1 35 A 1 9 A 1 15 A 1 35 A 1 9 A 1 35 A 1 3 A 1 3 A 1 3 A 1 3 1 33 1 33 1 31 1 33 1 35 1 31 1 33 1 35 1 33 1 33 1 33 1 9 1 15 1 7 1 7 1 13 1 37 1 7 1 37 1 7 1 17 1 17 1 9 1 11 1 3 1 3 1 31 1 33 1 31 1 33 1 11 1 31 1 33 1 31 Revised February 2004 TB200408 13 amp 9 9 10 1 8 33 21 26 6 24 3 OPTION 8
117. LT ETA UMG H 33 0 9 12 Instruction Not Found i HC trema 33 09 15 Seral llega x Eo uuu uuu ee 33 Quality Control and Standard Curve Errors ccccccccccccseccceeeeeeeeeeeeeseeeeseeeeseeeseeeseeeeseeeseeseeesseeeesseeees 34 ME GO NI PN NETT 34 0 oma duds Ete E 34 6 10 3 Set more THAN TWO Un qu 34 0104 apro PRINTER 35 Bierzo qa e Nm mm au u 36 611 Int erruptby Mechanical 36 6 11 2 Turned Off During 37 O 1 37 6112 Enter OPK CIST 2 38 6 11 5 Check Reagent Volume 1 38 6 11 6 Insufficient Reaction 38 O 39 0121 E78 0716 39 0 122 CPU Failure 1 m 40 CA 500 Series S M Revised December 2001 g Error Messages Alphabetical Order B Barcode Scanner Driver OM LLL LLL I suit altes tbi pipe i DID 23 Barcode Scanner T
118. LVE MFP 6 V OPERATOR S MANUAL CA 500 OPERATORS MANUAL CA 500 2 TRAP CHAMBER PROCEDURE PUSH VIAL PV 10 PCB 6350 WITH ROM PCB NO 2132 STANDARD PCB NO 2132 2 CIRCUITS PCB NO 2132 3 CIRCUITS PCB NO 4086 PCB NO 6362 PCB NO 9264 PCB NO 2134 PCB NO 9260 PCB NO 7015 PCB NO 9265 PCB NO 9265 PCB NO 6350 WITH ROM FOR CA PCB NO 7015 2 FLASH MEMORY D DIMER LED ASSY 800NM D DIMER LED ASSY 575NM PCB NO 2156 STANDARD CLOT AT3 PCB NO 2156 2 CIRCUITS CLOT PCB NO 2156 3 CIRCUITS AT3 DD PCB NO 2156 4 CIRCUITS DD 800NM PCB NO 2156 5 CIRCUITS DD 575NM PCB NO 2157 PCB NO 6373 PCB NO 6375 ASSY PCB NO 9303 DETECTOR THERMAL ASSY DETECTOR THERMAL ASSY CHROMOGENIC LED ASSY CHROMOGENIC LED ASSY COAGULATION LED ASSY COAGULATION LED ASSY COOLER THERMAL ASSY SERNSOR IC COOLER THERMAL ASSY THERMAL SENSOR ASSY THERMAL SENSOR ASSY TRANSFORMER POWER ASSY 200V TRANSFORMER POWER ASSY 100V POWER SWITCH ASSY CA 500 RINSE BOTTLE FLOAT SWITCH ASSY 2L WASTE BOTTLE FLOAT SWITCH ASSY 2L RINSE BOTTLE FLOAT SWITCH ASSY 5L WASTE BOTTLE FLOAT SWITCH ASSY 5L ID WIRING CORD ID WIRING CORD A 4 3 UNIT Q TY PAGE A 1 5 A 1 39 A 1 5 A 1 39 A 1 36 A 1 31 A 1 31 A 1 39 A 1 33 A 1 33 A 1 39 A 1 33 A 1 5 A 1 11 A 1 11 A 1 11 A 1 9 A 1 5 A 1 17 A 1 7 A 1 9 A 1 5 A 1 25 A 1 27 A 1 5 A 1 5 A 1 11 A 1 11 A 1 11 A 1 11 A 1 11 A 1 11 A 1 11 A 1 7 A 1 5 A 1 5 A 1 25 A 1 11 A 1 35 A 1
119. MOTOR ASSY SYRINGE MOTOR ASSY CYLINDER ASSY CYLINDER ASSY PISTON ASSY OPERATION PANEL ASSY OPERATION PANEL ASSY OPERATION PANEL ASSY VR ASSY VR ASSY OPERATION PANEL BASE ASSY EMERGENCY STOP SW ASSY EMERGENCY STOP SW ASSY PRINTER ASSY SAMPLE TABLE ASSY STANDARD SAMPLE TABLE ASSY ID SAMPLE TABLE BASE ASSY SAMPLE TABLE BASE ASSY ID MOTOR ASSY ID MOTOR ASSY ID ASSY ID ASSY SAMPLE RACK SENSOR ASSY SAMPLE RACK SENSOR ASSY DRIVE ARM ASSY X AXIS SLIDER ASSY X AXIS SLIDER ASSY Z AXIS BASE ASSY PIPETTE HOLDER ASSY PIPETTE HOLDER ASSY PIPETTE CRUSH SENSOR ASSY Y AXIS MOTOR ASSY Y AXIS MOTOR ASSY Z AXIS MOTOR ASSY Z AXIS MOTOR ASSY MIXER MOTOR ASSY MIXER MOTOR ASSY CATCHER ASSY A 4 4 UNIT Q TY 2 2 2 2 2 2 2 na i 2 2 2 2 2 2 2 2 2 2 2 2 2 o 2 2 o AAA 1 9 1 35 1 11 1 35 1 9 1 11 1 9 1 11 1 11 1 35 1 9 1 13 1 13 1 35 1 13 1 35 1 5 1 21 1 23 1 35 1 21 1 21 1 21 1 3 1 25 1 27 1 27 1 35 1 27 1 27 1 35 1 25 1 3 1 3 1 3 1 38 1 3 1 35 1 3 1 35 1 3 1 35 1 7 1 7 1 15 1 17 1 17 1 19 1 19 1 15 1 35 1 17 1 35 1 19 1 35 1 17 11 12 10 34 4 1 6 Revised Februa
120. Move the pipette to the setting position by using XY TEST key 4 Use T N lt and gt keys to adjust the pipette tip to become the center of the sample cup Adjust the pipette tip to become center of the sample cup Figure 4 3 11 Pipette Tip Position 5 Press 2 TEST key to descent the pipette The pipette detects the 60 pL of distilled water and stops 6 Use f lt and gt keys to adjust the pipette tip to become the center of the sample cup 7 Press Z TEST key again to ascend and descend the pipette Verify that the pipette is placed at the center of the sample cup 8 Press XY ORG key to return the pipette head to the home position 9 Adjust 8 buffer in the same way CA 500 Series S M 4 17 Revised December 2001 2 2 Adjustment 1 gt the sample cup holder to CA CLEAN Holder Place 60 uL of distilled water into 4 mL sample cup 60 uL of Distilled Water 7 Sample Cup Figure 4 3 12 Sample Cup with 60 uL Distilled Water 2 Move the pipette to the adjustment position by using XY TEST key 3 Press Z ADJUST key to descent the pipette 4 The pipette detects the 60 uL of distilled water and stops Z pulses will be stored as the setting value in the memory when Mecha Position adjustment is completed Descent the pipette lower limit to the lowest for Z axis adjustment value Adjust after executing Section 4 3 4 Position Adjustment Procedure of Pip
121. Now ORG Tube catch X 1785 1780 Y 2316 2316 8 Z 1221 1221 Pipette Bottom 10 Wash 0 Figure 4 3 7 Pipette Lower Limit Adjustment Screen 2 Use numeric keys to input the value When Z Adjustment is disable by the insufficient pulse input 1275 for temporary The pipette lower limit value 1250 is set by pressing 1 2 5 0 Enter Quit and returns to the Mecha Position Adjustment screen Be sure to press Enter key to set the value 3 When pressing FIX key 25 pulses are added to Z pulse setting value and the value is automatically set as the pipette lower limit CA 500 Series S M 4 15 Revised December 2001 4 3 5 Position Adjustment Procedure of Pipette 4 reag 1 5 reag 9 6 reag 10 Continuous Z position adjustment is possible on software version 00 14 or later Refer to 4 3 6 2 1 XYZ Adjustment 1 sample cup holder to the reagent rack No 1 Place 60 uL of distilled water into the 4 mL sample cup 60 uL of Distilled Water 2 a Sample Cup Figure 4 3 8 Sample Cup with 60 uL Distilled Water 2 Verify that the 4 reag 1 is shown on the left center of the screen If not change to 4 reag 1 by using Pos and Pos keys 3 Move the pipette to the setting position by using XY TEST key 4 Use T N lt and gt keys to adjust the pipette tip to become the center of the sample cup Adjust the tip to become center of
122. PS R11L INVERTER CXA K05M C INVERTER INV 5 ADAPTOR ID 23 G WIRING CORD NO 2701 WIRING CORD NO 2702 WIRING CORD NO 2703 FUSE HOLDER CAP 031 1663 EUROP FUSE HOLDER CAP 031 1666 N AME FUSE 125V6A UL TSC 6A N1 FUSE 250V6 3A ST4 6 3A N1 N A FUSE 250V3 15A NO 19195 EUROP FUSE THERMAL 125V5A TYPE210 PRINTER FTP 421MCL001 BATTERY LITHIUM CR17450SE 2 CJ2 BATTERY LITHIUM CR23500SE CJ2 BATTERY LITHIUM CR23500SE CJ2 SW REGULATOR 1 508 5 SW REGULATOR 1 1508 12 SW REGULATOR LCA450S 24 XJCM SW REGULATOR 1 1508 24 WIRING CORD COVER TRASH COVER CA 500 ZSB REAR COVER COVER SENSOR SHUTTER B DM1374 CATCH HOLD PLATE DM1358 VIBRATION ARM DM1163 CATCH BOX DM1357 STAY DM1102 REAR PANEL DM0933 WIRING CORD HOLDER DM1220 C ARM PLATE DM1221 LOCK SPRING DM1298 SS BASE PLATE DM1361 SS ACTIARM DM1362 PULLEY NO 185 TIMING BELT B216MXL4 8 TIMING BELT B488MXL9 5 PULLEY NO 143 O RING NO 16 HINGE R 45 N GREASE TOA FIXING SCREW TL 233 SPRING PIN KSSC 2017 O RING P 8 NITRIL O RING P 8 NITRIL O RING P 39 O RING P 39 4 1 UNIT Q TY p gt gt lI 1 ES e PAGE A 1 5 A 1 36 A 1 39 A 1 33 A 1 3 A 1 15 A 1 23 A 1 3 A 1 25 A 1 17 A 1 25 A 1 25 A 1 33 A 1 35 A 1 35 A 1 35 A 1 5 A 1 5 A 1 5 A 1 5 A 1 5 A 1 11 A 1 25 A 1 5 A 1 5 A 1 35 A 1 9 A 1 9 A 1 9 A 1 9 A 1 5 A 1 9 A 1 17 A 1 3 A 1 17 A 1 19 A 1 17 A
123. Panel by removing two screws 2 Disconnect Photo Sensor connector and Motor connector 3 Move the pipette to Rinse Cup and disconnect the tubing 4 gt Remove the volumetric unit motor by loosening two screws item 4 Figure C 4 Removing Volumetric Unit Motor 5 The motor is fixed by two fixing screws item 5 Adjust the belt tension so that the belt is indented 4 mm when it is pushed at the center by a finger 6 for the adjustment of the tension between Idler and Pulley adjust it at Pulley position Adjust the belt tension so that the belt is indented 4 mm when it is pushed at the center by a finger Pulley 6 Idler Figure C 5 Adjusting Belt Tension CA 500 Series S M C 4 Revised December 2001 E C 4 Drive Arm Assembly 1 _ Remove all the panels 2 Remove the belt by loosening the tension of X motor by loosening two screws item 2 Be careful as the left side idler comes off 3 Remove four screws on the right and left sides and two screws item 3 on top side of the top plate aluminum plate Figure C 6 Removing Drive Probe Assembly 4 gt Remove two fixing metals clamping the FPC item 4 and remove the FPC from PCB No 9260 5 gt Remove the screw fixing the X axis shaft and loosen the screw of the aluminum plate on the left side PCB No 9260 Figure C 7 Removing FPC CA 500 Series S M C 5 Revised Dec
124. RT NO 247 SUPPORT NO 247 VIAL SPACER 1 SPACER FOR RUBBER SHOE CAUTION MARK NO 16 CAUTION MARK NO 16 CAUTION MARK NO 16 CAUTION MARK NO 16 CAUTION MARK NO 208 CAUTION MARK NO 208 CAUTION MARK NO 208 CAUTION MARK NO 208 INSTRUCTION LABEL 1 JAPANESE INSTRUCTION LABEL 1 JAPANESE INSTRUCTION LABEL 2 INSTRUCTION LABEL 2 INSTRUCTION LABEL 3 JAPANESE INSTRUCTION LABEL 3 JAPANESE INSTRUCTION LABEL 7 INSTRUCTION LABEL 7 LID NO 9 LID NO 9 LID NO 9 LID NO 9 BOTTLE TANK A RINSE 2L BLUE BOTTLE TANK A WASTE 2L RED SILICONE GREASE THERMAL 800 8 CONNECTING TUBE NO 3 CONNECTING TUBE NO 50 RUBBER TUBE NO 7 HYDRAULIC CONNECTOR NO 23 NIPPLE NO 9 NIPPLE NO 123 TUBE SILICONE 1 32 X3 32 F7391 TUBE SILICONE 2MMID X 3MMOD TUBE SILICONE 4MMID X 8MMOD TUBE SILICONE 4MMID X 8MMOD TUBE SILICONE 1 5MMID X 6MMOD TUBE SILICONE 6MMID X10MMOD TUBE SILICONE 2 X 4MM SR 1554 TUBE SILICONE 2MMIDX5MMOD CLR TUBE TEFLON 1 2MMID X 2 0MMOD TEFLON 5MMID X25MMOD TUBE TEFLON 1 5MMID X 2 5MMOD A 4 2 UNIT Q TY 10 1 100 50 100 na d gt cl n 1 UNSALABLE UNSALABLE 1 1 UNSALABLE UNSALABLE 1 O 10 10 10 20 20 10 10 10 10 PAGE A 1 19 A 1 21 A 1 39 A 1 39 A 1 13 A 1 39 1 3 1 3 1 36 1 37 1 39 1 5 1 36 1 39 1 33 1 3 1 31 1 31 1 31 1 31 1
125. Reagent heater pipette CA 500 Series S M 6 39 Revised December 2001 8 6 12 2 CPU Failure Number Number System bus error Address error Illegal instruction Divided by 0 program bug 97 Interrupt controller initializing error 256 Undefined interrupt Monitor Timing Always Monitor Method Monitors signals around CPU board CA 500 s Action Alarm and system stops in locked condition alarm cannot be reset Turn the power OFF 1 Probable Cause No 3 4 5 97 256 1 Failure of PCB No 6362 2 Failure of PCB No 7015 No 6 1 Main program failure of PCB No 7015 2 Confirmation by the operator 1 Turn the power OFF ON 2 Contact your Sysmex service representative 3 Confirmation by Service Engineer No 3 4 5 97 256 1 Check the data check operation of the service program 2 Check clog of PCB No 7015 socket 3 Failure of PCB No 6362 No 6 1 Main program failure CA 500 Series S M 6 40 Revised December 2001 g SECTION 7 SCHEMATICS To Cover 500 WIRING TUBING 7 1 500 Series S M Revised December 2001
126. Susmex SERVICE MANUAL Automated Blood Coagulation Analyzer CA 500 section 1 Specifications section 2 Hydraulics and Mechanics section 3 Electronics section 4 Adjustment section 5 Service Program section 6 Error Messages and Troubleshooting section 7 schematics Appendix A Parts List Appendix Installation Appendix C Disassembly SYSMEX CORPORATION KOBE JAPAN SYSMEX CORPORATION TECHNO CENTER 4 4 4 Takatsukadai Nishi ku Kobe 651 2271 Japan TELEPHONE 81 78 991 1911 FAX 81 78 992 3274 URL http www sysmex co jp SYSMEX AMERICA Inc 1 Nelson C White Parkway Mundelein IL 60060 U S A TELEPHONE 1 847 996 4500 FAX 1 847 996 4505 URL http www sysmex com SYSMEX UK LIMITED Sunrise Parkway Linford Wood East Milton Keynes Buckinghamshire MK14 6QF U K TELEPHONE 44 1908 669555 FAX 44 1908 669409 SYSMEX EUROPE GmbH Bornbarch 1 22848 Norderstedt Germany TELEPHONE 49 40 527260 FAX 49 40 52726100 SYSMEX SINGAPORE PTE LTD 2 Woodlands Sector 1 01 06 Woodlands Spectrum Singapore 738068 TELEPHONE 65 221 3629 FAX 65 221 3687 Copyright 1999 through 2001 by SYSMEX CORPORATION First Edition November 1999 Second Edition December 2001 All right reserved No part of this book may be reproduced in any form or by any electronic or mechanical means including information storage and retrieval systems without written permission from the publisher Printed in Japan Part Code Num
127. TUBE SILICONE 2 X 4MM SR 1554 TUBE SILICONE 2MMID X 3MMOD TUBE SILICONE 2MMIDX5MMOD CLR TUBE SILICONE 4MMID X 8MMOD TUBE SILICONE 4MMID X 8MMOD TUBE SILICONE 6MMID X10MMOD TUBE TEFLON 1 2MMID X 2 0MMOD TUBE TEFEONA 5MMID X 2 5MMOD TUBE TEFLON 1 5MMID X 2 5MMOD TUBE TOALONE 3MMID X 6MMOD TUBE TOALONE 3MMID X 6MMOD TUBING ASSY PIPETTE VACUUM PUMP ASSY VACUUM PUMP ASSY VIALSPACER NO VIBRATION ARM DM1163 VOLUMETRIC PISTON ASSY VOLUMETRIC PISTON ASSY ASSY ASSY WASTE BOTTLE ASSY WASTE BOTTLE ASSY CA 5H 2L WASTE BOTTLE ASSY CA 5H 2L WASTE BOTTLE ASSY CA 5H 2L EU UK WASTE BOTTLE ASSY CA 5H 2L EU UK WASTE BOTTLE ASSY CA 5H 5L WASTE BOTTLE ASSY CA 5H 5L WASTE BOTTLE ASSY CA 5H 5L EU UK WASTE BOTTLE ASSY CA 5H 5L EU UK WASTE BOTTLE FLOAT SWITCH ASSY 2L WASTE BOTTLE FLOAT SWITCH ASSY 5L WIRING CORD COVER WIRING CORD HOLDER DM1220 WIRING CORD NO 2701 WIRING CORD NO 2702 A 3 5 PART NO 365 1333 3 289 9377 2 289 9379 0 289 9378 6 289 9376 9 663 0165 4 663 0165 4 663 0217 1 663 0217 1 662 2207 3 662 2207 3 342 1815 1 342 1816 4 663 0373 5 662 2209 1 662 2208 7 663 0211 9 461 9128 7 322 9151 5 442 5292 3 442 5279 4 442 5305 4 442 5280 9 442 5315 1 442 5290 6 442 5290 6 442 5295 4 442 5416 1 442 5452 5 442 5452 5 442 5475 1 442 5475 1 663 0189 3 663 0197 3 663 0197 3 365 2231 4 324 9077 1 663 0164 1 663 0164 1 663 0169 9 663 0169 9 663 0210 5 663 0210 5 663 0
128. Temperature Control Accuracy within 15 2 C Room temperature 15 C 30 C 6 Waiting time for setting temp within 30 minutes 7 Reagent Mixing Function None accommodation accommodated DADE 5 mL Reagent Bottle with outer diameter of 22 3 mm Buffer 3 35j CACLEANI 1 _ No j Detection Function 1 Principle of Measurement Coagulation Method Scattered Light Measuring Method wave length 660 nm Chromogenic Method Calorimetric method wave length 405 nm Immunoassay Colorimetric method wave length 575 nm 2 Number of Detectors Coagulation Method 4 detection wells High and Low sensitivity automatic switching Chromogenic Method 1 detection well Immunoassay 1 detection well 3 No of Incubation wells 6 wells 4 Temperature Control Accuracy within 37 0 0 5 C ambient temperature 15 C 30 C within 37 0 1 0 C for Incubation Well 5 Waiting time for setting temp within 30 minutes Pipette Rinsing Function 1 External Container Rinse Bottle and Waste Bottle 2 Rinse Cup Probe Rinse Cup Outside and Probe Rinse Cup Inside 3 Rinsing Function Pipette is rinsed by controlling the syringe and the solenoid valve with applying the pressure on the Rinse Bottle 4 Waste Draining The waste is aspirated by controlling the solenoid valve with applying vacuum on the waste bottle CA 500 Series S M 1 10 Revised December 2001 8 11 12 13
129. Unit built in Main Unit CA 530 CA 540 3 Immunoassay Unit The immunoassay is available on Immunoassay Unit built in Main Unit CA 550 CA 560 4 Reagent Cooler Unit Cooling reagent for four parameters is available on Reagent Cooler Unit built in Main Unit CA 530 CA 540 3 Interface with Other Instruments 1 RS 232C 2 PC DPS C CA DPS SIS or Host Computer can be connected CA 500 Series S M 1 1 Revised December 2001 8 1 3 2 Power Source 1 Rated voltage AC 100 V 117 V 1090 AC 230 V x 1596 2 Type of Current Direct Current 3 Frequency 50 or 60 Hz 4 Maximum power consumption CA 510 CA 520 CA 530 CA 540 CA 550 CA 560 310 VA or less 320 VA or less 380 or less 400 or less 380 VA or less 400 VA or less 5 Class and Type of Electrical Protection Class l electrical apparatus Type B electrical apparatus 1 3 3 Dimensions and Weight 1 Dimensions excluding projections 540 mm width X 487 height X 470 mm depth 3 respectively 2 Weight CA 510 CA 520 CA 530 CA 540 CA 550 CA 560 43 kg 44 kg 44 kg 45 kg 44 kg 45 kg 1 3 4 Each Unit Function and Operation 1 Main Unit Power Switch Turns the power ON OFF 2 Display Unit Displays the analysis registrations analysis results stored information and operation contents on the LCD 3 Control Unit Using LCD and Touch Panel controls the operation in dialog 4 XYZ Drive Mechanism Dispenses sample and reagent Tran
130. Use to set the selected method and returns to Flag Threshold Setting screen Return Key Use to quit selecting method and returns to Flag Threshold Setting screen Ready IP Replace Rack YES Flag Threshold Settings Sysmex Clot PT NC threshold 15 SC threshold 7 8 9 Minimum reportable time 7 4 5 6 Masking time 5 0 1 2 3 Next T 0 Enter Factory Default Quit Figure 5 6 3 Numeric Keys Next Key Use to display next four parameters Factory Default Key Use to initialize selected detection method 1 4 Key Use to move cursor to the desired parameter Return or Quit Key Press this key to quit the flag threshold settings Then the setting renew confirmation display will appear Select the appropriate key Cancel Cancels the renewed setting and returns to the Service Menu screen FIX Changes to the renewed setting and returns to the Service Menu screen Continue Returns to the Service Setting screen and allows continuous operation CA 500 Series S M 5 16 Revised December 2001 g 5 7 TEST MODE 1 Press Special Operate Service Test Mode keys to start then the following screen will be displayed oysmex si Replace Rack YES Test Mode Anl Check Mode OFF Rinse Wait Time 120 Sec Barcode Mod OFF
131. VICE SETTING Use to the default parameter when initializing From the Main menu press Special Operate Service Service Setting keys Ready IP oysmex Replace Rack YES Service Setting Chrom ON Immuno OFF Wavelength 5 5 nm DFbg ON APTT Warm 180 Sec D Dimer Init for DD PLUS b d Next Return Figure 5 2 1 Service Setting Screen 1 Press to select the item to be set Selected item is indicated in reversed 1 Chrom Immuno TTO thru PFDP Select to set the selected parameter s analysis protocol automatically when performing initializing ON To set OFF Not to set 2 DFbg Derived Fbg oet the 4th calculation parameters of PT standard curve as ON Valid OFF Invalid 3 APTT Warm When selecting this item the numeric keys will appear The APTT incubation time can be set using numeric keys in 30 sec increments If the APTT incubation time is set the default setting of APTT incubation time is automatically set when performing initializing Numeric keys To input value Enter To set the input value The input vale is verified Next Option Pressing this key alternates ON or OFF Return Use this key to quit the settings and then the following keys will appear Cancel Cancels the renewed setting and returns to the Service Menu screen FIX Changes to the renewed setting and returns to the Service Menu screen Setting da
132. Value 1 Number of analysis on one sample 2 Reagent volume monitor Inactivate 3 Test name 11 12 CA 500 Series S M 5 29 Revised December 2001 g 6 Auto validation output Setting Description IP built in printer HC host computer Within Limit Normal sample Error Sample QC Sample QC sample Printout without Graphics 7 Mark Limits Parameter 8 Fbg Limits Upper Limit LowerLimit Unit Fg 475 0 9 Replication Limits APTT _ TO NT Out of Limit Abnormal sample S TTO N 06 AT III 10 Report Limit Se PT 70 1300 0 0 o gt 0 0 8 0 125 0 CA 500 Series S M 5 30 Revised December 2001 g 11 Calibration 1 1 1 1 1 1 O Oojojojojoj o c 12 Host Computer NOTE When CA 1000 format is selected a sample ID number up to 13 digits is used When CA 500 format is selected a sample ID number up to 15 digits is used Note that when the sample ID number consists of 15 characters and CA 1000 format is used the upper 2 digits are automatically deleted 13 Barcode Scanner Not connected Check Digit None ITF Kind 2 NW 7 Knd2 CODE 39 JAN 8 14 Date Format Japanese domestic CA 500 Series S M 5 31 Revised December 2001 g 5 11 12 Standard Curve Settings 1 PT Calculation Parameters
133. Wash Test Mode OFF ADC BUFF OFF VLin interim OFF Return Figure 5 8 1 Test Mode Screen T and 4 Keys Use to move cursor The selected item is displayed in reversed Next Option Key Press this key to set the analysis check mode barcode mode 7 and rinse reagent volume check selection ON or OFF Numeric Keys When the cursor is moved to Rinse Wait Time numeric keys appear for the setting Refer to Section 5 9 2 below Return Key Press this key to quit the Test Mode Then the renew setting confirmation display will appear Press the appropriate key Cancel Cancels the renewed setting and returns to the Service Menu screen FIX Changes to the renewed setting and returns to the Service Menu screen Continue Returns to the Test Mode screen and allows continuous operation 5 7 1 Analysis Check Mode This setting is used to switch the minimum reportable time ON All data will be displayed and output OFF No data will be displayed and output on following condition PT Below 7 sec APTT Below 15 sec 5 7 2 Rinse Wait Time Set the time period to leave the rinse solution within pipette during manual pipette rinsing Time between 1 and 600 seconds can be set CA 500 Series S M 5 17 Revised December 2001 g 5 7 3 Barcode Mod 7 This setting is used for the use of bar code check digit Modulus 7 ON Used OFF Not used 5 7 4 Wash Test Mode This setting is used to ent
134. ach the presumed percent of the coagulation curve 1 3 5 2 Chromogenic Substrate Method 1 1 4 1 4 1 Calorimetric Method Rate Method PERFORMANCE INTENDED USE AND EFFECTIVENESS Intended Use This unit measures the coagulation of the plasma or serum component of anti coagulant sodium citrate added human blood 1 4 2 1 Performance Measurement Parameters and Display Parameters Default Unit is shown in 1 Prothrombin Time PT second Calculated Parameters a Prothrombin Activation Percent 90 b Prothrombin Ratio c International Normalized Ratio INR INR d Derived Fbg for export specification only mg dL 2 Activated Partial Thromboplastin Time APTT second Calculated Parameters a APTT Ratio b Activation Percent for European and UK specifications only 3 Fibrinogen Fbg second Calculated Parameters a Fibrinogen Concentration mg dL 4 Thrombo Test Plasma Method second Calculated Parameters a Activation Percent 90 b INR for European and UK specification only CA 500 Series S M 1 3 Ds Revised December 2001 8 5 Normotest second Calculated Parameters a Activation Percent 96 b INR for European and UK specification only 6 Thrombin Time for export specifications only second 7 Factor Il V VII VIII IX X XI XII second Calculated Parameters a Activation Percent 90 8 Protein C Coagulum
135. adjustment will be Numeric Keys 1 thru 999 displayed when cycle count exceeds the preset period DA replaced in the near future DA replaced CV Limit A limit to check the fluctuation 0 0 thru 100 0 5 0 number adjustment tube aspirated from the reagent vial volume tube the reaction tube Aspiration speed A speed of the calibrator aspiration 300 thru 1300 650 Dispensing speed A speed of the calibrator dispensing 300 thru 109 650 CV check tube The minimum value of data to calculate CV Numeric Keys MEME thru 5 3 number CV will be calculated when the preset number or more data exists Mean check tube Anumber of data when adopting mean value Numeric Keys thru 5 2 The mean value becomes the adjustment value when the number of data is within preset value If not the mean value without a maximum and minimum data becomes as the adjustment value Quit Key Press this key to quit the LED Calibration settings then the setting renew confirmation display will appear Select the appropriate key Cancel Cancels the renewed setting and returns to the LED Calibration screen FIX Changes to the renewed setting and returns to the LED Calibration screen Continue Returns to the LED Calibration screen and allows continuous operation 5 10 1 Adjustment Value Calculation Method The adjustment value for each reagent is calculated as below 1 Decide whether the data should be cal
136. agent vial detects the liquid surface and then the volumetric syringe descends to aspirate the reagent At this time the solenoid valves does not function closed When dispensing the probe moves to the heated reaction tube catches that reaction tube then moves to the dispensing position and dispenses the heated reagent into the reaction tube After dispensing the mixing motor mixes the sample and reagent in the tube and sets it in the detecting well e Rinsing after Reagent Dispensing and Mixing After reagent dispensing and mixing the probe moves to the Probe Rinse Cup inside The Probe Rinse Cup inside valve opens to flow rinse solution out of the probe Next the probe moves to the Probe Rinse Cup outside the probe tip touches the liquid and then a drop adhering on its tip is removed The probe then moves to rinse solution and aspirates CACLEAN After aspiration it moves to the Probe Rinse Cup inside and the probe valve opens to feed out rinse solution At this time the syringe piston moves to dispense the rinse solution The probe moves to the Probe Rinse Cup outside and both the Probe Rinse Cup valve and the valve on probe open to rinse the probe f Probe Rinsing The Rinse Probe key causes the probe to move to Probe Rinse Cup outside and detect the syringe home position Then the probe moves into the Probe Rinse Cup inside and any liquid remaining on the probe tip is removed After that the probe moves to rins
137. amp X AXIS SLIDER ASSY Code No Drawing Description Qty per Unit 663 0217 1 1 TABLE LOCK MECHANISM ASSY 1 663 0200 8 1 SOLENOID ASSY 1 228 3753 3 2 PHOTO INTERRUPTER LG 217D 3 1 663 0181 4 11 XAXIS SLIDER ASSY 1 663 0185 9 11 Y AXIS MOTOR ASSY 1 342 1816 4 12 TIMING BELT 488 9 5 1 CA 500 Series S M A 1 15 Revised December 2001 8 500 2 5 A 77 e 5 4 u J i CA 500 Series S M A 1 16 Revised March 2003 303A066 200049 500 2 Axis Base Assy m s m isis I I Code No 663 0182 8 663 0183 1 663 0188 0 663 0186 2 662 0222 2 228 4050 8 663 0189 3 324 9078 4 324 9076 7 342 1815 1 663 0393 0 663 0394 3 322 9152 9 CA 500 Series S M Drawing Description Z AXIS BASE ASSY PIPETTE HOLDER ASSY CATCHER ASSY Z AXIS MOTOR ASSY PCB NO 9264 PHOTO IC SENSOR PS R11L TUBING ASSY PIPETTE CATCH BOX DM1357 CATCH HOLD PLATE DM1358 TIMING BELT 216 4 8 Z1 SLIDER C ASSY DU1469 Z2 SLIDER C ASSY DU1468 ZSB REAR COVER A 1 17 Il lI ll lx Revised March 2003 303A066 200049 CA 500 Catcher Assy CA 500 Series S M A 1 18 Revised December 2001 8 500 CATCHER ASSY 8 HOLDER ASSY Code No 6
138. and pin 7 sensor is shielded CN4 PCB No 2134 pin 9 GND and pin 7 sensor is shielded CN1 PCB No 2134 pin 17 and pin 18 GND sensor is shielded CN1 PCB No 9260 pin 17 and pin 18 GND sensor is shielded CN105 PCB No 6332 pin 7 and pin 14 GND sensor is shielded When the motor does not operate a Any of motor PCB No 9264 PCB No 2134 X axis wiring cord and PCB No 4086 is faulty Replace and confirm Failure of drive mechanism a Check for flaws on the shaft b Ifthe shaft is free from flaws the problem is the bushing CA 500 Series S M 6 11 Revised December 2001 g 6 4 5 Tube Catch Error Position Monitor Timing Just after the reaction tube catching operation Monitor Method Tube detection sensor monitors the Tube catch error CA 500 s Action Interruption 1 Probable Cause 1 Atube cannot be caught 2 Tube catch operation is obstructed 3 Tube catcher tried to catch a reaction tube not in the order 4 The catcher is too dirty to function 5 Mis positioned catcher 6 Defective catcher 7 Tube detection sensor is dirty 8 Failure of tube detection sensor 9 Failure of PCB No 9264 10 Failure of PCB No 2134 11 Failure of PCB No 9260 12 Failure of X axis wiring cord 13 Failure of PCB No 6362 2 Confirmation by the Operator 1 Remove anything that is obstructing the catching 2 Clean any contamination using alcohol or the like 3 Confirmation by Service Engineer 1 When
139. ate number of pulses of moved probe The probe moves to these setting values by pressing XY TEST and 2 ADJUST keys 3 Display pulses of the probe position Moves to these setting values by pressing XY TEST and Z ADJUST keys 4 Display status of the sensor at the home position on each XYZ drive axis Black Circle gt Detected Activated White Circle gt Not Detected Not Activated 5 Display pipette lower limit Usually it is automatically set 25 pulses added to Z position adjustment value 6 Display selected setting position Normal Fine Adjustment Mode Reverse Basic Position Adjustment Mode 7 Display status of each sensor on the probe Black Circle gt Detected Activated White Circle gt Not Detected Not Activated REFERENCE The reaction tube held by the catcher is detected by the reflection sensor at the detection position When Z is at the home position the black circle will be displayed because usually the sensor is in front of the catcher 8 Reset Liq Sen Key Reset the detecting status of the liquid surface sensor Pipette Bottom Tube Free Tube Catch Keys Change depending to the setting position Pipette Adjustment Pipette Bottom Catcher Adjustment Tube Free gt Tube Catch Z ADJUST Key Move the pipette or the catcher according to the setting pulses 11 Z ORG Key Return the pipette or the catcher to Z home position XY TEST Key Move XY drive
140. ature Error High Detector Temperature Error Low Detector 4 Temperature Error High Incubator Temperature Error Low Incubator 3 Temperature Error High Room Temperature Error Low Room enne 6 EEO 5 5 u 12 Tube Release Emor AGS is 5 4 5 mmm 13 T med Of Dunno Operaliftu 37 V V salon y Er MR c P 2 iere LOW ME 39 W MY AS Do PRETERITO ER mem 7 X X Axis Home Position 8 Y AxISTlome POSION ETOT m T hasa 9 Z Z AXIS DOWN EI Or uuu u u u u uuu uuu l llu 11 Z AXIS Home POSIIIOGH EMOL uu uu L u 10 CA 500 Series S M Revised December 2001 g SECTION 6 ERROR MESSAGE Y Axis Home Cover Sensor Z Axis Home X Axis Home Position Sensor Position Sensor Position Sensor e g ah Pipette Crash eZ Z Sensor eis Sampler Cover Paper Empty Sensor gt Open Sensor Syringe Home Position Sensor
141. band pass over 600 nm Transmitted Light Detection Detector Unit 1 port Light Source LED NLPB 500 Photo Diode 51133 silicon diode Filter 405 nm band pass filter Transmitted Light Detection Immunoassy Detector Unit 1 port Light Source LED TLGE159P Photo Diode 1133 silicon diode Filter 5 5 nm band pass filter 2 Other Incubation well 6 wells Heater 28 W film heater Overheat protection 76 thermal fuse 2 4 3 Assembly Diagram e Insulation Bushing Shield Case PCB No 2132 Photo Detector Block CA 500 Series S M 2 5 Revised December 2001 8 2 5 REAGENT COOLING UNIT 2 5 1 Outline To cold store reagents electronic cooling element Peltier element cools the 4 hole reagent set 2 5 2 Specifications Functions Cooling source Peltier element 1 piece DC 12 V applied Cooling 1 unit of DC fan and fin type radiator Temperature detection Semiconductor temperature sensor 1 unit 2 5 3 Assembly Diagram A t Hold Plate Hold Sponge Cold Plate Sarcon Insulating Sponge Peltier element Sarcon Heat Sink CA 500 Series S M 2 6 Revised December 2001 8 2 6 VOLUMETRIC UNIT 2 6 1 Outline The volumetric unit is used to measure a predetermined volume of sample reagent buffer and rinse 2 6 2 Specifications Functions 1 Drive System Drive source Unipolar type stepping motor 1 2 phase excitation constan
142. ber Printed Manual 601 8244 3 CD ROM Manual 601 8268 2 SECTION 1 SPECIFICATIONS To Cover u A 1 1 Le Nane and 1 1 1 3 Configuration and Dimensions 1 1 1 3 1 Configuration and Expandability of the System 1 1 Loz PONS 1 2 1 3 9 Dimensions and Fu oo nx Ee aAa 1 2 1 3 4 Each Unit Function and Operation a 1 2 1 3 5 Principles of Measurement a a a 1 3 14 Performance Intended Use and Effectiveness 1 3 141 mended USG 1 3 N PEOC E mme 1 3 oto om 1 9 15 AGOuSIIG Noise Level 1 13 1 6 Environmental Condilions LULU 1 14 1 6 1 Operating 1 14 1 6 2 Reagents to be 4 1 14 I ACEITE TET 1 15 CA 500 Series S M Revised December 2001 g SECTION 1 SPECIFICATIONS 1 1 OUTLINE The Sysmex CA 500 Automated Blood Coagulation Analyzer obtains clotting times by detecting changes in scattered light intensity reflected from a d
143. ber 2001 8 4 Stability Temperature Stability Variation of measurement Activation for AT 11 at 15 C C45 or 35 C C35 from that at 25 C lies within the following ranges when this formula is used C15 or C35 C25 x 100 C25 PT APTT second 8 or less Fbg HpT second 1090 or less 96 10 less D Dimmer ug L 10 less otability within a day Variation of measurement Activation 9o for AT III at the time of 2 4 and 8 hours from that at 30 minutes after the power is turned on initial value lies within the following ranges The ambient temperature at the time of measurement should be within the specified range Temperature variation must be within 5 Measurement after 2 4 or 8 hours Measurement at 30 minutes x 100 Measurement at 30 minutes PT APTT second 8 or less Fbg HpT second 1090 or less 96 1090 or less D Dimmer ug L 10 or less Long term Stability daily variation Variations in measurement values Activation 9o for III during the continuous 10 days lie within the following ranges The ambient temperature at the time of measurement should be within the specified range Temperature variation must be within 5 C Measurement after second day Mean Measurement x 100 Mean Measurement PT APTT second 8 or less Fbg HpT second 1090 or less 96 10 less D Dimmer
144. bushing Failure of PCB No 9260 Failure of PCB No 6362 Failure of X axis motor assembly 0 Failure of PCB No 4086 poc OD US Ue 2 Confirmation by the Operator 1 Remove the obstruction in X axis drive mechanism 2 Turn off the power supply then turn it on again 3 Confirmation by Service Engineer 1 Retighten the screw of the pulley of motor 2 If home position cannot be detected even when the drive mechanism is operated a Check whether the light shield is defective or not Suspect Part Test Points Expected Value Position sensor CN2 PCB No 9260 pin 1 and pin 2 GND 5 0 25 2 9260 2 3 5 V gt 0 V when the sensor is shielded CN105 PCB No 6362 pin 13 and pin 15 5 V 0 25 V GND CN105 PCB No 6362 pin 15 and pin 5 GND 5 V 2 0 V when the sensor is shielded 11 7 1177 Figure 6 2 Sensor Signal Output 3 When the motor does not operate a Any of motor wiring cord float cable or PCB No 4086 is faulty Replace and confirm b Turn the pulley by hand If it does not move the motor or drive mechanism is faulty 4 Failure of the drive mechanism a Check for flaws on the shaft b If the shaft is free from flaws the problem is in the bushing CA 500 Series S M 6 8 Revised December 2001 8 6 4 2 Y Axis Home Error Monitor Timing At time of Y axis home position sensing Monitor Method The photo interrupter shades the light of Y
145. culated The error Err2 will be displayed and the operation will be stopped if any data fulfills as follows 1 AD Value gt 1023 2 AD Value x 0 3 DA Value gt 1023 4 DA Value x 0 5 Indicated Value delta x AD Value 6 Indicated Value delta AD Value delta 1023 DA Value 2 2 Check OV When there are 3 or more data of the setting value CV will be calculated to decide whether the data is within the allowable range If the data exceeds the allowable range the error Err2 will be displayed and the operation will be stopped 3 Calculate Adjustment Value When there are 3 or more data of the setting value the mean value without a maximum and minimum data will be calculated and becomes as the adjustment value If there are 2 or less data the mean value of all becomes as the adjustment value CA 500 Series S M 5 23 Revised December 2001 g 5 11 FACTORY SETTING VALUE TABLE 5 11 1 Position Adjustment 1 Pipette Position X Y Sampler 2265 2265 STAT Sample 2265 ReagentRack Position X Y Reagent 9 Reagent 10 Rinse CA CLEAN 1 Buffer X Rinsingcup Position X Y Inside 1537 Outside 1339 Tube Rack Position Position X Y Tube 1 Tube 5 Tube 26 Tube 31 Tube 35 Tube 56 2 Catcher Incubation Well 1 Incubation Well 3 Incubation Well 4 Chrom Well Immuno Well Peostin X Y Z Reagent Dispense 137 512 29 Discard Well 154
146. de If it does not function the followings are conceivable Since the liquid level detection is latched each time reset it on the screen to check Suspect Part Test Points Expected Value Liquid Sensor CN2 PCB No 2134 pin 1 is touched with Indicator on LCD changes from tweezers or the like white circle to black circle PCB No 2134 pin 16 GND and pin 5 5 V when probe touches liquid surface CN1 PCB No 9260 pin 16 GND and pin 5 surface CN105 PCB No 6362 pin 13 GND and pin 2 surface CA 500 Series S M 6 14 Revised December 2001 g 6 5 2 Sampling Error Position Monitor Timing When the probe has been apart from liquid surface after sample or reagent aspiration Monitor Method The capacitance liquid level detection sensor monitors the probe has not been apart from the sample or reagent CA 500 s Action In the case of a sample the instrument stops In the case of a position of reagent the concerned analysis will not be done The related analysis parameter of reagent will not be done thereafter In the case of rinse reagent however emergency stop is made 1 Probable Cause 1 Plasma volume is insufficient 2 Power supply is not frame grounded in a noisy and static charged environment 3 Failure of PCB No 2134 2 Confirmation by the operator 1 Check whether a sample location rack number matches its registration or not 2 Secure the frame grounding of the power supply 3 Confirmation by s
147. e O ring CA 500 Series S M 2 9 Revised December 2001 8 29 BAR CODE READER UNIT ID COMPLETED PARTS 2 9 1 Outline This unit drives the bar code reader which reads ID labels affixed on the sampler set on the sample table 2 9 2 Specifications Functions 1 Drive System Drive Source Unipolar type stepping motor 2 phase excitation constant current drive Drive Transmission Timing belt type Resolving Power Approx mm step Drive Speed Approx pps at high speed in constant control oensor For drive unit home position transmission type 1 unit 2 ID Specifications Light Source Receptor Element LED CCD image sensor Read Width 80 mm ocan Cycles 500 scans 500 decodes per second Interface Conforms to RS 232C Power Source DC 5 V 300 mA Corresponding Code CODE39 NW 7 Industrial 2 of 5 CODE 128 etc CA 500 Series S M 2 10 Revised December 2001 8 2 10 PUMP UNIT PRESSURE PUMP VACUUM PUMP COMPLETED PARTS 2 10 1 Outline The pump unit comprises the pressure pump that applies positive pressure into the bottle to feed rinse solution from the rinse bottle into the system and the vacuum pump that applies vacuum into the bottle to feed out waste from the system into waste bottle 2 10 2 Specifications Functions 1 Pressure Pump Structure Pressure 250 mmHg as adjusted 2 Vacuum Pump Structure Vacuum Approx 180 mmHg as not adjusted 2 10 3 Assembly Diagram Pressure Pump Vacuum Pump
148. e Cause The sample rack is removed The sample rack is not properly mounted Failure of sample rack sensor assembly Failure of wiring cord wiring cord with spiral Failure of PCB No 6362 Q N 2 Confirmation by the operator 1 Place the sample rack properly 3 Confirmation by Service Engineer 1 Check the dirt on sample rack table and or it is free of foreign matters 2 Short circuit the pin 20 and pin 18 of relay connector If it can be monitored on the switch sensor screen the sample rack drawer might be faulty Check the harness and sample rack sensor 3 If the above step 2 does not solve the trouble short circuit the pin 14 and pin 12 of CN111 on PCB No 6362 If this solves the trouble the wiring cord wiring cord with spiral is faulty If not the PCB No 6362 is faulty CA 500 Series S M 6 21 Revised December 2001 g 6 6 3 Replace Sample Rack Drawer Monitor Timing When starting analysis Monitor Method Photo interrupter incorporated is shaded the light shield attached to the sample rack drawer CA 500 s Action Warning is displayed and no analysis is performed 1 Probable Cause 1 The sample rack drawer is not properly mounted Defective light shield of sample rack drawer Failure of photo interrupter sensor Failure of solenoid valve assembly Failure of PCB No 6362 W The sample rack drawer is removed 2 Confirmation by the operator 1 2
149. e catcher retainer 3 9 TL l gt NR L J RS E lt Catcher Retainer L Figure B 4 Removing the Catch Retainer CAUTION e Unless the retainer is removed the instrument cannot operate CA 500 Series S M B 4 Revised December 2001 g B 4 Attach Trap Chamber 1 X Attach the furnished trap chamber to the rear panel Connect the trap chamber tube green to the waste vacuum nipple green on the rear panel WARNING e When draining the trap chamber always wear rubber gloves After completing the operation be sure to wash hands in anti septic solution If hands should be contaminated with blood or the like there is a hazard of being infected by pathogenic bacteria Waste Vacuum Nipple Green Trap Chamber Nipple Yellow Figure B 5 Attaching the Trap Chamber CA 500 Series S M B 5 Revised December 2001 g B 5 Connect Rinse Bottle and Waste Connect the rinse bottle and the waste bottle to the nipples on the instrument rear panel 1 Connect Rinse Bottle 1 Connect the rinse bottle to the pressure supply nipple black and rinse aspiration nipple blue on the rear panel at places where the color matches with the bottle 2 Connect the level detecting float switch to the float switch connector on the rear panel 2 Connect Waste Bottle 1 Connect the waste bottle tube red to the waste drain nipple
150. e of printer paper ix Serial output x X Other self diagnosis by service mode 2 Sample Abnormality monitoring function i Upper and lower limit judgment PT Fog TTO NT TT Display when the measured data exceeds the preset range 23 External Input Output Function The I O terminal in accordance with RS 232C is provided as bit serial voltage I O 24 Protection Function Over heat protection thermal fuse Pipette Unit and Detector Block Mechanical stop switch Light Shield cover open close switch Sampler position sensor 25 Display Languages Capable of displaying six languages such as Japanese English French Italian German and Spanish ocreen displays and messages should be consistent with those of existing models 1 5 ACOUSTIC NOISE LEVEL Noise level should be within the following values The measuring position is 1 meter from the front of the product 1 Stand by status 58 dB or less 2 Measuring operation status 60 dB or less Temporary noises less than 65 dB continued within 5 seconds are produced on occasions such as home positioning of X Y table or syringe drive mechanism are not included CA 500 Series S M 1 13 Revised December 2001 8 1 6 ENVIRONMENTAL CONDITIONS 1 6 1 Operating Environment 1 Ambient temperature 157 35 2 Relative humidity 30 85 non condensing 3 Atmospheric pressure 70 106 kPa 4 Place to be instal
151. e solution and aspirates CACLEAN 1 After aspiration the probe aspirates rinse solution 2 minutes to clean the its inside Now the probe moves to the Probe Rinse Cup inside and causes the probe valve to open and feed out rinse solution At this time the syringe piston moves to dispense the rinse solution Next the probe moves to the Probe Rinse Cup outside and both the Probe Rinse Cup outside valve and the valve on probe open to rinse the probe After rinsing the probe returns to the home position CA 500 Series S M 2 3 Revised December 2001 8 2 3 PRESSURE CIRCUIT 2 3 1 Structure The pressure circuit of this system consists of two circuits the pressure circuit designed for filling solution by the pressure pump and the vacuum circuit designed for liquid draining by the vacuum pump The pressure system comprises the pressure pump circuit for its control pump driving circuit a bottle for filling and a valve for filling line circuit The vacuum circuit system comprises the vacuum pump pump driving circuit and drain line circuit with a waste bottle For the hydraulic circuit that uses pressure to flow rinse solution 2 3 2 Operation 1 Outline of Pump Operation The filling and draining by this system are performed by the pressure and vacuum Therefore the pressure is applied to the rinse bottles connected to the outside of the system a Pressure System The pressure system generates pressure by the pressure pump and utiliz
152. e the new setting value in the memory and output the value on the built in printer and then return to the sub menu 1997 05 09 OFFSET GAIN 118 188 134 250 134 249 111 168 133 244 133 242 108 123 130 162 130 164 118 176 134 243 134 243 127 690 127 690 Figure 4 2 5 Output Example 2 When the adjusted value is discarded and the adjustment is completed press Cancel key In this case the setting value data is not changed and returned to the sub menu 3 When the adjustment is continued press Continue key In this case the screen returns to the previous set screen so you can continue the adjustment 4 2 6 Target Value List for Adjustment Detector Well Specified Values na Display Value for Offset and Gain Tels LOW Pr iow OFFSET Ebonite Stick 30 1 20 1 20 s i 910 Scattering Stick 910 20 l Distilled Water 3800 4000 3800 4000 Varies lot by lot 480 Scattering Stick 480 15 480 15 GAIN a 500 5 4 9 1 Revised February 2004 TB200408 1 7 CA 500 Series S M 4 2 7 LED Auto Calibration Press Special Operate Calibration keys The LED Calibration screen will appear Sysmex poo IP y Replace Rack YES LED Calibration Target Value 900 Vial Type Cup 7 8 9 Please set Calibrator on Reagent Holder 1 and set Clean1 on
153. ecified PC card etc cannot assure the operation 14 Sensor Entry U314 316 327 The X Y Z axis sensor signal the volumetric syringe sensor signal and the ID Unit sensor signal are input as the home position sensors at the motor drive position The Liquid Surface Sensor signal latched from the Y Z RELAY Unit and the Probe Crash signal are input As the other sensor signal entries the Mechanical Stop Switch the Cover Open Switch the Sample Rack Switch the Sample Table Switch the Rinse Bottle Sensor the Waste Bottle Sensor and the Tube Catch Sensor are activated 15 DIP SW Entry SW202 U207 Among 9 bits of the Dip Switch the 1 8 bits can be used as port entries CA 500 Series S M 3 19 Revised December 2001 16 Detector Block Interface 0515 506 514 502 513 505 501 This circuit sends various commands such as switching command for signals from Detector Block scattered light 1CH 4CH transmitted light 5CH transmitted light for Immunoassy 6CH the H L Gain Amplifier command Offset voltage control command Gain voltage control command and the A D converting command Also the interface circuit drives the LED which is the light source of Detector Block with the constant current Switching of each channel signal is performed every 20 ms by the multiplexer U515 control command and then the procedure for the selected signal is performed By the H L Gain Amplifier U506 1 2 3 pin U 514 switchin
154. ed for taking in each switching regulator power Transformers with 100 V or 200 V are installed on delivery Power Supply Board PCB No 4086 For Built in Printer power source 15 V For Analog Circuit power source PCB 6362 2132 2134 9260 CA 500 Series S M 3 5 Revised December 2001 3 3 No 2132 PD Photo Diode Pre Amplifier LED Relay PCB No 2156 PD2 Photo Diode Pre Amplifier LED Relay 3 3 1 Function These PC Boards amplify the detector signal in channels CH1 CH6 and drives LEDs for these channels There are four kinds of boards for CH2 4 6 for CH1 3 5 for CH1 3 and for CH2 4 Actually this board is used with composing two kinds of the board Refer to the table below This circuit detects the scattered light on the channels CH1 CH4 the transmitted light on the channel CH5 on Detector Block ATIII and the transmitted light on the channel CH6 on Detector Block Immunoassy amplifies by the current voltage converter and output to PCB No 6362 MAIN or PCB No 6373 MAIN 2 K to be Used PCB No 246 No 2156 Immuno CA 550 560 662 0285 7 2 4 PCB 2132 Standard 510 520 530 540 662 0217 3 Coag Chrom EUM IM 3 PCB No 2156 2 Circuits Coag 662 0282 6 PCB 2132 3 Circuits CA 530 540 550 560 662 0219 1 PCB No 2156 3 Circuits 662 0283 0 Chrom Immuno Detector Block 3 3 2 Block Diagram GER aee n es c c RR E im ms
155. els Reference maximum power consumption Table B 2 CA 510 CA 520 CA 530 CA 550 CA 560 MAIN UNIT 310VA 320VA 380VA 380VA The power cord is 1 8 m long Table B 3 Width mm Depth mm Height Weight kg Main Unit 540 470 487 45 Figure B 1 Instruments Dimensions CAUTION sure to place the rinse bottle and waste bottle on the base which the instrument is set Do not put them on the instrument or there is a possibility the instrument may break down or fail to produce correct results CA 500 Series S M B 2 Revised December 2001 g B 3 Remove Shipping Clamps Remove the shipping clamps used on movable components of the instrument 1 Open the front cover of the main unit 2 Remove the X Y mechanism fixing metals Two fixing metals are retained with screws as shown Loosen the screws and remove the metals CAUTION Unless the fixing metals are removed the instrument cannot operate Figure B 2 Removing the Fixing Metals CA 500 Series S M B 3 Revised December 2001 g 3 Move sample probe unit by hand to a place where it is easy to operate Remove the sample probe retainer Sample Probe Retainer Figure B 3 Removing the Sample Probe Retainer CAUTION Unless the retainer is removed the instrument cannot operate 4 gt Raise the sample probe by hand to a place where it is easy to operate Remove th
156. ember 2001 8 6 Open left side aluminum plate and remove shaft and Drive Arm Assembly 7 Remove the tubing from the clamp by removing two left screws two screws of your side three screws the top and the four right screws in order to remove Drive Arm Assembly The cover can be removed without removing Drive Arm Assembly from the main unit Be careful not to catch or crush the tubing Figure C 8 Removing Drive Probe Unit Cover 8 After removing the cover you can access PCB No 2134 No 2134 D Ys k zt ML De um s Me nd P eS Td E a Sec Figure C 9 Accessing PCB No 2134 9 The X slider can be removed after removing the chassis 10 The linear slider and the bearing block on the lower side are included in the X slider 11 After removing six screws fixing the resin cover at the back side of the Z axis base you can access PCB No 9264 Z Axis Home Position Sensor K slider Z axis base Figure C 10 Accessing PCB No 9264 CA 500 Series S M C 6 Revised December 2001 8 12 Loosen tension of the Y axis Motor by loosening two screws item 12 and remove by sliding the motor 13 Remove four screws fixing Z axis base on the linear slider and Z Axis Base Assembly can be removed item 13 Figure C 11 Removing Z Axis Base Assembly 14 The pipette is fixed by a screw on the up
157. emory Initialization and adjustment setting of X Y axis position CA 500 Series S M 1 12 Revised December 2001 8 18 Standard Curve Setting Function Standard curve of seven parameters 14 parameters in CA 550 and CA 560 can be set at six points or less within the measurable range Setting Standard Curve is performed by the Auto dilution or Manual Entry Manual dilution analysis is available only in CA 550 and CA 560 Two kinds of standard curves can be set to one parameter only in CA 550 and CA 560 Settings should be given to each parameter individually 19 Analytical Algorithm corresponding to V Lin Integral CA 550 and CA 560 only As a new analysis method analytical algorithm equivalent to V Lin Integral is provided 20 APTT Initial Reaction Check Algorithm CA 550 and CA 560 only An algorithm to check APTT s initial reactions is newly provided 21 Detector Block Self Checking Function CA 550 and CA 560 only Besides the already provided functions to adjust the detector block a function is newly provided that the analyzer self monitors the state of the detector block and carry out auto calibration 22 Error Alert Function 1 Unit Error monitoring function i Temperature of heater section Shortage of reagent Presence or absence of sample rack Shortage of rinse solution lt V Overflow from the waste bottle vi Operation of mechanical parts vii Operation of printer viii Shortag
158. emperature Error High Detector Temperature Error Low Detector Monitor Timing When READY 1 minute interval During analysis At time of detection start Monitor Method A D converter reads the thermal sensor data embedded in the sample probe as follows Room temperature less than 30 Temperature error when exceeds the range 36 0 38 0 temperature above 30 Temperature error when exceeds the range 36 0 40 0 C 1 Probable Cause Room temperature became outside the range between 15 35 C Check whether any obstacle is in front of the ventilation fan or the ventilator is too close to the wall Failure of temperature sensor Heater failure Failure of PCB No 6362 Failure of PCB No 4086 Failure of main unit fan 2 Confirmation by the Operator 1 Confirm room temperature by checking temperature displayed on the main unit 2 Provide sufficient space around the ventilator 3 Confirmation by Service Engineer 1 Check the main unit fan is operating or not If not inside temperature rises causing it impossible to keep the detector at 37 Suspect Part Test Points Expected Value Temperature sensor Temperature sensor connector pin 1 green 5 and pin 3 black GND Temperature sensor connector pin 2 white 0 35 V to 0 39 V and pin 3 black GND CN115 PCB No 6362 pin 4 and pin 6 GND CN115 PCB No 6362 pin 5 and pin 6 GND 0 35 V to 0 39 V Heat
159. enewed setting and returns to the Service Menu screen FIX Changes to the renewed setting and returns to the Service Menu screen Continue Returns to the Service Setting screen and allows continuous operation Ready IP Replace Rack YES Vial Settings oysmex Vial Name Cup Std 4 00 mL Dead 0 10 mL Area mm 105 683 Offset 0 Z Pulse Change Down Figure 5 7 2 Reagent Vial Setting Screen 1 4 Key Use to move cursor to the desired item Para Change Key Use to change the selected item by displaying Next Option key or numeric keys Z Pulse Down Key Use to move to the descend pulse adjustment screen Return or Key Returns to Reagent Vial setting screen CA 500 Series S M 5 19 Revised December 2001 8 The changeable parameters are as follows Key to be Used Changeable Range Vial Name Name of Reagent Vial Full Keyboard 9 characters maximum Alphabets and Numbers Normal Volume mL 0 01 thru 99 99 by 0 01 mL Dead Volume mL 0 00 thru 99 99 by 0 01 mL Section Area of Vial mm 0 000 thru 999 999 by 0 001 mm Offset Number of Offset Pulse Numeric Keys 999 thru 999 by 1 pulse from Adjustment Position to Dead Volume IP Ready Replace Rack YES Reag Vial Settings Sysmex Vial Name Cup Std 4 00 mL Dead 0 10 mL Area mm2 105 683 Offset 0 Adjust Z pulse down Set Cancel Figure 5 7 3 Z Pulse
160. ensing 100 uL of water in incubation well 6 from reagent holder 1 the reaction tube is moved to detection well Confirm that the temperature of water at detection well is within 37 1 It is recommended that the temperature of water at detection well is adjusted within If the temperature value is not within the range return to the Temperature adjustment procedure section 4 4 3 input the new S value as follows When the measured value is higher than the range 37 0 3 use key to add 5 to the current When the measured value is smaller than the range 37 0 3 use key to subtract 5 to from the After the S value change perform steps 1 6 again Press Quit key to finish the test Then the screen will return to the Test Menu display 2 3 4 5 6 3740 3 C 7 Nozzle S value current Nozzle S value 8 5 5 5 Tube Transfer Test Verify the reaction tube transfer operation 1 Press Special Operate Service Test Menu Tube Trans Test keys to start then the following screen will be displayed CA 500 Series S M Ready IP Sysmex Replace Rack YES Tube Trans Test Tube No 1 Warm No 1 Detect No 1 di Set Return Figure 5 5 6 Tube Transfer Test Screen Revised February 2004 2 To verify Tube Transfer operation 1 Transfer the tube of the specified tube rack in the following order incubation well reagent dispense gt detect
161. ensor Z Control 5 0009 syringe ID EN 5 ID 4086 CW COW x oo PS CLK SCOUNTUP CTC Home Pos Sensor 0 mechanical stop sw L ich mechanical Interface Circuit INT PCB No 4086 PS B current down Interface CHEESE MUS Figure 3 15 Stepper Motor Control Circuit 20 Vacuum Pump Control This circuit controls the vacuum pump for aspirating waste 21 SV Control Sampler Table Lock Control This circuit controls two solenoid valves and the actuator for the sampler table locking 22 Buzzer This circuit controls the buzzer ON OFF by the output port 23 Mixing Motor Control This circuit controls the stirrer motor ON OFF by the output port The mixing motor driving power voltage is adjusted at VR101 The regulated voltage on the PCB No 4086 is controlled by this VR101 24 Bus Interface This circuit is composed by the Address Bus the Data Bus the Address Decoder U203 203 205 206 etc and the RD WR signal generating circuit U208 CA 500 Series S M 3 22 Revised December 2001 g 3 8 4 3 8 5 3 8 6 3 9 3 9 1 3 9 2 3 9 3 Setting and Adjustment Refer to Section 4 for the adjustment LED and Test Point Refer to Section 4 for the adjustment Assembly Drawing Refer to Section 4 for the adjustment PCB No 7015 MEMORY Program Memory
162. er Offset Circuit PCB No 4086 PS Pressure Pump Control G 8 5 Interface Comparator Latch Circuit uit OFF Interface tock RESET CPU RESET Y 16M 500KHz PCB No 4086 PS Interface X PCB No 4086 inten X Motor PS nterface Control PS Syringe ee Liquid Surface Sensor Ifa Pipette Cras Home Pos Sensor Syringe ID EN PCB No 4086 CW CCW PS CLK Home Pos Sensor ID Mech Stop Sw Cover Open Sw PCB No 4086 CWIGCWI ra Latch Mech Stop Sw Interface Circuit INT for ID Unit Motor INT X PS Current down Interface ST j Syringe Sample Rack Sw Sample Table Sw Rinse Bottle Sensor T Waste Bottle Sensor Tube Catch Sensor Vacuum Pump Control Sample Table Lock SV 1 SV 2 Mixing Motor Control PCB No 4086 PS DIP SW Effective PIO i Buzzer Interface lt CLOC Generator Divider Circuit Interrupt Controller CPU CPU RESET MEMORY CARD Interface Slot EEPROM WORK RAM l RTC L CPU SIO CPU SIO CPU 510 PIO Figure 3 11 PCB No 6362 and 6373 Block Diagram CA 500 Series S M 3 17 Multiplexer 15 Voltage Monitoring 24 INT Voltage Multiplexer Monitoring CPU RESET ees PCB No
163. er connector pin 1 and pin 2 below 3 or over 7 8 PCB No 4086 pin 1 and pin 5 below 3 or over 7 NOTE Use high input impedance device Usually normal Digital Volt Meter input impedance is higher than 1 Mega and Oscilloscope is higher than 10 Mega CA 500 Series S M 6 4 Revised December 2001 g 6 2 3 Temperature Error High Cooler Temperature Error Low Cooler Monitor Timing When READY 1 minute interval During analysis No monitoring Monitor Method A D converter reads the thermal sensor data embedded in the cooler unit as follows Room temperature less than 30 Temperature error when exceeds the range 12 0 18 0 C Room temperature above 30 Temperature error when exceeds the range 12 0 20 0 1 1 Room temperature became outside range between 15 35 2 Check whether any obstacle is in front of the ventilation ventilator or the ventilator is too close to the wall 3 Failure of temperature sensor 4 Failure of Peltier cooler assembly 5 Failure of wiring cord Pertier 6 Failure of wiring cord Temperature sensor 7 Failure of PCB No 6362 8 Failure of PCB No 4086 9 Failure of main unit fan 10 Failure of cooler unit fan 2 Confirmation by the Operator 1 Confirm room temperature by checking temperature displayed on the main unit 2 Provide sufficient space around the ventilator 3 Confirmation by Service Engineer 1 Check the main unit fa
164. er the rinse solution amount check mode ON Enter the wash test mode for production and servicing use only In the Wash Test Mode the sample probe does not come down into the rinsing cup during reagent dispense sequence OFF Customer mode 5 7 5 ADC BUFF For Factory Use Only This setting is used for the factory use only ON Used OFF Not used 5 7 6 Vlin interim For Factory Use Only This setting is used for the factory use only ON Used OFF Not used CA 500 Series S M 5 18 Revised December 2001 g 58 REAGENT SETTING 1 Press Special Operate gt Service gt Reag Vial Settings keys to start then the following screen will be displayed Ready IP 5 Reag Settings Vial Name Std Dead Area Offset Cup 4 00 0 30 105 683 60 4 mL Vial 4 00 1 00 286 521 42 3 mL Vial 3 00 0 40 201 062 f PV 10 10 00 0 90 292 553 23 GW5 5 00 1 00 291 039 23 SLDVial 5 00 0 40 45 357 31 5 00 0 50 314 159 28 5 00 0 50 314 159 28 5 00 0 50 314 159 28 5 00 0 50 314 159 28 Set Return Figure 5 7 1 Reagent Vial Setting Screen 7 4 Key Use to move cursor to the desired reagent vial Set Key Use to set the selected reagent vial and returns to Reagent Vial Setting screen Return Key Press this key to quit the reagent vial settings Then the setting renew confirmation display will appear Select the appropriate key Cancel Cancels the r
165. ervice Engineer 1 Failure of PCB No 2134 2 Always secure frame grounding in a noisy environment CA 500 Series S M 6 15 Revised December 2001 g 6 5 3 Insufficient Reagent Holder No Monitor Timing At reagent aspiration Monitor Method The capacitance liquid level detection sensor monitors the insufficient reagent aspiration CA 500 s Action the case of a sample the instrument stops In the case of a reagent the concerned analysis will not be done The related analysis parameter of reagent will not be done thereafter In the case of rinse reagent however emergency stop is made 1 Probable Cause Reagent is not placed Reagent volume is insufficient Failure of sample probe Failure of PCB No 2134 Failure of Y Z relay harness Failure of PCB No 9260 Failure of X axis wiring cord Failure of wiring cord flat cable Failure of PCB No 6362 2 Confirmation by operator 1 Place a reagent 2 Check whether the reagent location holder No matches its registration or not 3 Confirmation by Service Engineer 1 Monitor the liquid sensor function in the Service mode If it does not function the followings are conceivable Since the liquid level detection is latched each time reset it on the screen to check Liquid Sensor CN2 PCB No 2134 pin 1 is touched with tweezers or the like white circle to black circle CN1 PCB No 2134 pin 16 GND and pin 5
166. es the pressure sensor to monitor and control the generated pressure to maintain a predetermined amount of rinse solution The rinse solution in the rinse bottle is kept under a certain pressure by the pressure controlling and it is supplied by opening the valve connected to the system b Vacuum System The vacuum circuit is released to the atmosphere at the rinse cup The vacuum pump operates only at the time of draining to aspirate the waste into its bottle The vacuum circuit is not monitored Instead checking is made on whether or not the liquid level becomes abnormal when the sample probe moves into the Probe Rinse Cup inside if waste is not drained properly the drain error occurs 2 Specifications Functions a Pressure Pump Pump type Drive power supply AC 100 V 50 60 Hz Pressure generation Over 300 g cm b Vacuum Pump Pump type Drive power supply AC 100 V 50 60 Hz Vacuum generation Over 100 g cm CA 500 Series S M 2 4 Revised December 2001 8 2 4 DETECTOR BLOCK 2 4 1 Outline The CA 500 detector block is provided with 4 scattered light detecting ports 1 transmitted light detecting port and 6 incubation wells The detector block is kept at 37 by the heater and the semiconductor temperature sensor 2 4 2 Specifications Functions 1 Analysis System ocattered Light Detection Detector Unit 4 ports Light Source LED H 2000L peak wavelength 660 nm Photo Diode 51133 silicon diode Filter R 60
167. essure PS error Multiplexer 2 Differential Comparator Latch x x x Sensor Amplifier Circuit Circuit i Offset Circuit Interface 4086 Pressure Pump Control Figure 3 14 Pressure Control Circuit CA 500 Series S M 3 21 Revised December 2001 g 19 Stepper Motor Control U310 311 302 305 303 With using two stepper motor control IC 0009 U310 311 this circuit controls each stepper motor of the X Y Z volumetric syringe The motor home position sensor signal and the mechanical switch latch signal are taken as a OR circuit therefore as soon as the mechanical switch is turned ON the operation immediately stops Also the Z Axis sensor is taken as a OR circuit with the liquid surface detector sensor and the probe crash sensor therefore in the case the probe is moving downward by these signals the operation immediately stops The current down signal controlling the current of the driver when the motor stops is output from P10 U302 305 The ID Unit stepper motor is controlled by the CTC U303 and the peripheral gates clock ESET cpu RESET BB V 6M SO0KHz o 4086 Interface AABB Y Motor PS Control 5 0009 X PCB No 4086 AABB PS AA BB Interface syringe Liquid Surface Sensor BE UM ar ProbeCrash Home Pos S
168. ette 3 Pipette Lower Limit Adjustment when it stops before detecting liquid surface Set 650 pulse for the pipette lower limit of the reagent rack 5 Adjust 8 buffer in the same way CA 500 Series S M 4 18 1 Revised December 2001 4 3 7 Continuous Z Adjustment Procedure of Pipette Ver 00 14 or later 9 1 XY Adjustment 4 reag 1 5 9 16 10 7 reag rinse 8 buffer 1 2 3 4 5 Set the sample to reagent rack No 1 sample Cup Figure 4 3 13 Sample Verify that the 4 1 is shown left center of the screen If not change to 4 1 using Pos and Pos keys Move the pipette to the setting position by using XY TEST key Use 1 lt and gt keys to adjust the pipette tip to become the center of the sample cup Adjust 5 reag 9 6 10 7 reag rinse and 8 buffer in the same way 2 Z Continuous Adjustment GQ N N O 8 9 Select Reag1 by pressing Pos Press Enter Pulses and increase Z pulse by 50 steps using the numeric key Save parameters by pressing Return Fix Enter Mecha Position screen again Set Z axis Position Adjustment Tools 031 0171 4 for Reag1 through Reag10 Rinse and Buffer 12 places Select Reag 1 by pressing Pos Pos and press Z adjust Check the check boxes
169. evised December 2001 8 APPENDIX DISASSEMBLY To Cover C 1 Cooler UNCASSEMDIY u u uuu uum Q ESSES C 3 C 3 Volumetric Unit Assemply aa ut elc d daa ine qun sued sasawaqa 4 er a 5 C 5 Operation Panel Assembly CA 500 Series S M Revised December 2001 APPENDIX DISASSEMBLY C 1 Detector Unit Assembly 1 Remove Light Shield Cover with Hinge from Top Cover Also remove the screws for the stop bar for Light Shield Cover 2 Remove two screws fixing Left Side Cover and remove the cover by lifting upward 3 Remove Reagent Stage by removing 4 screws 4 gt Remove Detection Stage by removing 2 screws CAUTION Be careful not to hit the Detection Stage to the tip of the pipette Detection Stage Reagent Stage Figure C 1 Removing Reagent Stage and Detection Stage CA 500 Series S M C 1 Revised December 2001 8 For Detector Unit Assembly loosen Four screws 5 in the Figure 2 and remove it by sliding to the left side Disconnect relay Connector and PCB Connectors Channel 6 is fixed by two screws PCB No 9259 Immuno LED is fixed by one screw PCB No 9259 AT3 LED is fixed by one screw PCB No 2132 is tightened by four screws together with Sh
170. f 60 tests 2 Confirmation by the operator 1 Reduce the number of test registered in Work List 2 Replenish the reaction tube 3 Confirmation by Service Engineer The same as above 2 CA 500 Series S M 6 38 Revised December 2001 g 6 12 6 12 1 Voltage Low Limit Monitor Timing When analyzing when monitoring Monitor Method Monitors voltage CA 500 s Action Emergency stop 1 Probable Cause 1 The power fail is occurred 2 The momentary power fail is occurred 3 Instability of the AC line voltage 2 Confirmation by the operator 1 Confirm whether the power fail or the momentary power fail is occurred 2 Confirm whether AC supply to the Main Unit is over the capacity of connection tool 3 Confirmation by Service Engineer 1 Check the AC line voltage is stable within the capacity 2 Check the voltage between pin No 33 and 34 of the flat cable PS control harness between PCB No 4086 and PCB No 6362 is within 1 7 V 1096 3 the voltage is within above the PCB No 6362 might be faulty 4 n other case 1 Check the PCB No 4086 fuse is blown 2 PCB No 4086 is not blown flat cable might be faulty 3 If the PCB No 4086 is blown the following might be faulty by 24 V short circuit in Y Z drive PCB No 4086 e X PC board harness PCB No 9260 e X axis motor wiring cord PCB No 2134 Y Z relay harness PCB No 9264 Y axis motor Z axis motor
171. g between high sensitivity and low sensitivity in the Detector Block Adjustment on the Service mode is performed The signal of the Offset voltage control circuit 4502 U505 8 9 10 composed by 8 Bit D A converter and OP Amplifier is added on the above signal In addition the Gain voltage control is performed at the programmable gain amplifier U513 U505 5 6 7 composed by 10 Bit D A converter and the OP amplifier Both the Offset control value and the Gain control value are adjusted by the Detector Block Adjustment on the Service mode and stored in the EEPROM LED ON OFF is executed by controlling 20 mA constant current circuit of U506 for 1CH 5CH and the photo coupler PC1 of PCB No 2157 on Detector Block for 6CH These adjusted values are converted to the digital signals by the 13 Bit A D converter U501 Additionally as the signals other than the signals of Detector Block 5 V 24 V voltage level signals and the pressure sensor signal are entered which enables the voltage monitoring and the pressure indication 4 Constant Reference IF 2 om Current Circuit Voltage for LED 4 6V LED 8 Bit D A 10 Bit D A CH1 6 gt OFF SET Programmable Adjustment Gain Amp 13 Bit A D Converter INT 24 Vol Monitor PIO 5 Vol Monitor Pressure Monitor Figure 3 12 Detector Block Interface CA 500 Series S M 3 20 Revised December 2001 g 17 Temperature
172. g to Section 4 4 2 2 Enter the service mode 3 Select Special Operate gt Service gt Adjust Temp Control Ready IP Replace Rack YES EMEN Temp Control Cooler 15 0 128 5 128 Nozzle 128 5 128 128 5 128 doo M S Manual Clear Change Entry Figure 4 4 1 Temp Control Screen 4 Touch the desired sensor area to adjust the temperature M XXX is Main value and S XXX is Sub value The cursor must be at S XXX position IMPORTANT Do not change the value This is the preset value during shipping inspection for the temperature control circuit on the PCB No 6362 It is not necessary to adjust it in the market field oince the value is stored in EEPROM on PCB No 6362 there may be the case where it is erased Then input the M XXX value by referring to the label attached on the memory card socket 5 Change the provided Sub value S XXX so that the displayed temperature should be the same as the measured temperature Use the numeric keys which appears by pressing Manual Entry key keys When pressing key the displayed temperature will increase decrease When numeric keys used the displayed temperature will change after pressing Enter REFERENCE The Sub value is fixed by the shipping test and attached to the PM parts for the maintenance purpose adjustment after shipment is not basically required
173. he end time for analysis The judgement value of polynomial approximate expression result Width to search variable analysis starting time Use of variable analysis starting time The modulus for variable analysis starting time calculation The modulus for variable analysis starting time calculation The modulus for variable analysis starting time calculation The modulus for variable analysis starting time calculation The modulus for linearity range The mixing time for sample The mixing time for reagent The slant of calibration The segment of calibration The parameter for dilute ratio of standard curve analysis ON accuracy equal to the CA 1500 OFF conventional accuracy Use to output the settings for all tests to the built in printer Numeric Keys When the cursor is moved to each setting value numeric keys appear as below to input the value CA 500 Series S M Revised December 2001 8 oysmex Ready Replace Rack YES Flag Threshold Settings Bioactivity Method for PT for TTO for PT for HpT for PT THS for F Int for APTT for F Ext for PTT ACT for CLOT1 for PTT FS for CLOT2 for PTT PSL for CLOT2 for Fbg Next Return J FIX Figure 5 6 2 Detection Method Selection Screen Next Key Use to switch detection methods of Bioactivity Method Chromogenic Method and Immunoassy Method 1 4 Key Use to move cursor to the desired item FIX Key
174. he float switch connector is disconnected 3 Failure of float switch 2 Confirmation by the Operation 1 Empty the waste bottle 2 Securely connect the float switch connector 3 Confirmation by Service Engineer 1 If an error can be solved by the short circuiting 2 pins connector on the rear panel for float switch the float switch is failed 6 3 2 Replenish Rinse Reagent Monitor Timing At time of analysis start before sample dispensing Monitor Method The float switch in the rinse bottle monitors the liquid level CA 500 s Action Interruption 1 Probable Cause 1 The rinse liquid is insufficient in the rinse bottle 2 The connector of the float switch is disconnected 3 Failure of float switch 5 Failure of PCB No 6362 2 Confirmation by the Operator 1 Replenish rinse solution 2 Securely connect the float switch connector 3 Confirmation by Service Engineer 1 If an error can be solved by the short circuiting 2 pin connector on the rear panel the float switch is failed CA 500 Series S M 6 7 Revised December 2001 8 6 4 MOTOR ERRORS 6 4 4 X Axis Home Position Error Monitor Timing At time of home X axis position sensing Monitor Method The photo interrupter shades the light of X axis drive mechanism CA 500 s Action Emergency stop 1 Probable Cause Drive mechanism operation is obstructed Loosened pulley of motor Failure of home position sensor Defective light shield Flaw on shaft Failure of
175. he surface are compared with the reference voltage approximately 2 6 V 2 6 V 9 Flip flop U4 8 9 10 11 12 13 Liquid surface detection signal is latched by flip flop 2 Probe Crash Detection Circuit Probe crash is monitored by a micro switch in the probe holder normally ON The micro switch turns OFF when probe is pushed back and the probe crash signal is generated The probe crash signal is latched by flip flop 3 5 4 Settings and Adjustment Setting and adjustments are not necessary CA 500 Series S M 3 9 Revised December 2001 3 5 6 Assembly Drawing iL s e PA gt A e Cg Y 781 5 _ worl OF meg 8 8 11M CJ E dp m eur 5 ez p x e amp 5 L 1312 s UE pm d Se 3 x K 13 Figure 3 7 No 2134 Assembly Drawing CA 500 Series S M 3 10 Revised December 2001 3 6 PCB 4086 PS Power Source Motor Driver 3 6 1 Function This PC Board takes in the Transformer power output AC100 V AC16 5 V and the Switching Regulator power output 5 V 12 V 24 V and delivers such power to each PC board directly or via the voltage regulator or each driver PCB No 6362 Main or PCB No 6373 Main 2 controls each driver Voltage Regulator Power Source for Analog Circuit 15 V voltage regulator
176. ield Case Including Isolation Bush PC Board of Photo Diode for AT 3 is fixed to Heater Block by one screw Thermal Sensor is inserted in the Block with Sarcon Turn over the Block and remove the aluminum plate by removing two screws item 11 Remove two fixing screws item 12 on the aluminum plate to remove the heater PCB No 9259 PCB No 9259 Shield Case Shield Case No 2132 Optical Block Figure C 2 Disassembling Detector Unit CA 500 Series S M C 2 Revised December 2001 8 2 Cooler Unit Assembly 1 Remove Light Shield Cover with Hinge from Top Cover Also remove the screws for the stop bar for Light Shield Cover 2 Remove two screws fixing Left Side Cover and remove the cover by lifting upward Remove Reagent Stage by removing 4 screws Slide and remove Cooler Unit by loosening a screw on the left side and two screws on the right item 4 Remove four plastic screws item 5 on Holding Plate to remove the Pertier Element Thermal Sensor is inserted in the Cooler Plate item 6 Cooler Fan is fixed by four fixing screws with spacers NL ON NOOO am s Holding Plate Holding Sponge Cooler Plate Sarcon Heat Isolation Sponge Pertier Sarcon Heat Sink Figure 3 Disassembling Cooler Unit CA 500 Series S M C 3 Revised December 2001 8 C 3 Volumetric Unit Assembly 1 Remove Right Side
177. ies S M Reagent Vial Setting Value mL mm2 0 6 286 521 0 6 201 062 0 9 292 553 0 6 291 039 LED Calibration Value W5 LD Vial Dispensing speed CV Check s CA 550 560 OFE 120 OFF 120 N N 00 N N N N N N 1 O O O O OFF 1 Ver 00 14 and later anal r1 Std mL mL mm2 100 0 9 292 553 04 Revised December 2001 8 4 2 2 2 7 3 3 1 5 11 10 Analysis Protocol 1 PT First Reagent Reagent volume 1 PT Rinse 11 2 APTT First Reagent Reagent volume 5 APTT Rinse 11 Second Reagent Reagent volume 7 CaCl2 Rinse 11 Activity APTT NOTE This depends on the APTT Incubation time setting Service Setting Japanese market 180 sec 3 Fbg First Reagent Reagent volume 3 Fbg Rinse 11 4 TT First Reagent Reagent volume 9 TT Rinse 11 CA 500 Series S M 5 27 Revised December 2001 g 5 First Reagent Reagent volume 8 TTO Rinse 11 High Sensitivit Max detection time 6 NT First Reagent Reagent volume 10 NT Rinse 11 High Sensitivit Max detection time 7 AT III Dilution volume 12 Buffer First Reagent Reagent volume 4 AT3 T Rinse 11 Second Reagent Reagent volume 6 AT3 S Rinse 11 Low Sensitivit NOTE There is a case that 4 7 are not set It depends on the Service Settings CA 500 Series S M 5 28 Revised December 2001 g 5 11 11 Customer Setting
178. ight shield is damaged or not on the sample rack drawer rear side If the signal on the pin 2 and pin 3 of the relay connector for solenoid assembly does not change even photo interrupter is shaded by the light shield the solenoid valve assembly or sensor is faulty If the above step 3 does not solve the trouble short circuit the pin 5 and pin 6 of CN112 on PCB No 6362 If this solves the trouble the wiring cord wiring cord from CN19 on PCB No 4086 is faulty If not the PCB No 6362 is faulty CA 500 Series S M 6 25 Revised December 2001 g 6 6 8 Exist same Sample Monitor Timing When barcode reading is completed Monitor Method oame sample No exists in one rack CA 500 s Action Warning 1 Probable Cause 1 Same sample No exists in one rack Barcode drive mechanism is obstructed Loosened pulley of motor Failure of BCR Bar Code Reader motor assembly Defective light shield Failure of sensor Flaws on shaft Failure of bushing Failure of wiring cord wiring cord with spiral Failure of PCB No 6362 Failure of PCB No 4086 Ec OD ees ss sa 2 Confirmation by the operator 1 Check the barcode label 2 Remove any foreign matters of the barcode drive mechanism 3 Confirmation by Service Engineer Remove any foreign matters on the barcode drive mechanism If the motor runs while barcode does not move retighten the pulley Check whether the light shield for the home position sensor is damaged or not
179. iluted sample with buffer reagent which are illuminated by red light of LED Incubated plasma taken from the centrifuged sample blood is rapidly mixed with warmed reagent and coagulation is performed and analyzed Its result can be automatically displayed and printed In accordance with the way of coagulation the chromogenics substrate method and the method of immunoassay are optionally available on this unit 1 2 NAME AND MODEL Name AUTOMATED BLOOD COAGULATION ANALYZER Model CA 510 CA 520 CA 530 CA 540 CA 550 CA 560 1 3 CONFIGURATION AND DIMENSIONS 1 3 1 Configuration and Expandability of the System 1 Configuration 1 Main Unit including Sampler Unit Pneumatic Unit and Built in Printer 2 Chromogenic Unit and Bar Code Reader can be connected according to the following combinations as the factory option Reagent Cooler Unit Chromogenic Unit Bar Code Reader CA 510 Option 520 Oo _ 50 OO _CA 540 O O _CA 550 X CASO j O O O 9 D 575 nm is used for Immunoassy 2 Factory Option 1 ID Bar Code Reader optional supply is available for CA 510 and CA 530 Sample ID numbers can be automatically read by Built in Type Bar Code Reader built in the sampler unit which can scan the samples in one rack and the STAT sample CA 520 CA 540 2 Chromogenic Unit The chromogenic analysis is available on Chromogenic
180. in 3 g cm Verify Steps 3 to 8 again and if the value is within the specified range Press the Return key 10 Confirmation screen will be displayed by pressing Return key 2 REFERENCE Pressure is adjusted at the factory in principle therefore it is not necessary to adjust in the field Setting values are stored in EEPROM on the PCB No 6362 or PCB No 6373 In case of erasing the EEPROM these printed values are attached on the memory card socket Select the appropriate key FIX The new setting value is fixed Cancel The new setting value is deleted and Adjust of Pump program will be quitted Continue The adjustment can be continued CA 500 Series S M 4 3 Revised December 2001 4 2 DETECTOR BLOCK SENSITIVITY ADJUSTMENT 4 2 1 Required Tools for Adjustment 1 CA Series Standard Scattering Stick Set 2 Reaction Tube 3 Micro Pipette 4 Ebonite Stick for adjusting offset value 4 2 2 Overview of Adjustment Screen Description Adjustment procedure starts from 4 2 3 Adjustment of Detector Well for Analyzing the Scattered Light 1 Verify that the ambient temperature where the unit is located is within the range of 15 35 The optimum recommended temperature range is 20 30 2 Start Service Mode 3 Select Special Operate Service Adjust Detector Gain 4 The Detector Gain screen will be displayed Sysmex ida y Replace Rack YES Detector Gain ch 1 High Gain A D
181. in adjustment and when the adjustment is completed the alarm sounds 5 Change the sensitivity to PT Gain and verity that both Offset and Gain values for PT Sensitivity are automatically set when changing Offset and Gain values for Low Sensitivity To set PT sensitivity individually execute the same procedure as 1 Offset Adjustment and 3 Low sensitivity Adjustment or enter values manually using numeric keys 6 Execute Steps 1 to 5 for channels 2 to 4 NOTE The gain adjustment and the offset adjustment have an influence on each other therefore reconfirm that the set value after each adjustment is within the specified range of values Refer to 5 9 2 Detector Block Adjustment Value for default value CA 500 Series S M 4 7 Revised December 2001 4 2 4 Adjustment of Detector Well for analyzing transmitted light Chromogenic and Immunoassy 1 Offset adjustment 1 Insert the ebonite stick for adjusting the offset value in the channel 5 of the detector well Sampie incubation Wall 3 Well 2 Well 1 VO Reaction Tube Trash CH 1 Detection Wel Detection Well Imjmunoass Chromo oon A CH6 CH5 Detectio Detection Well 4 O AN Woli 3 CH4 2 CH 3 000 Well 8 Well 5 Well 4 aes m omamo ob Figure 4 2 4 Detector Well Positions Chrom Immunoassy 2 Close the light shield cover 3 Select CH5 by using Channel Change key and select Offset position by pressing
182. ineer Suspect Part Test Points Expected Value Printer CN3 PCB No 9265 pin 2 and pin 1 5V 2 gt 0VvV when pulling the lock lever down when pulling the lock lever down for printer relaying when pulling the lock lever down 6 9 3 HC Line Monitor Timing When communicating with host computer Monitor Method Monitoring RS 232C DSR control signal CA 500 s Action Warning 1 Probable Cause 1 The connector cable is disconnected 2 The host computer is not turned on 3 The host computer is not ready to receive data 4 Failure of PCB No 6362 2 Confirmation by the operator 1 Check the connection with host computer 2 Turn on the host computer 3 Check the host computer data transmission 3 Confirmation by Service Engineer 1 Replace the PCB No 6362 CA 500 Series S M 6 31 Revised December 2001 g 6 9 4 HC Communication Error 6 9 5 HC CTS Time Out Monitor Timing During data transmission Monitor Method Monitors RS 232C protocol and time out CA 500 s Action Warning 1 Probable Cause 1 Failure of connection cable 2 Failure of host computer 3 Failure of PCB No 6362 2 Confirmation by the operator 1 Check the connection with host computer 2 Check the host computer 3 Confirmation by Service Engineer 1 Replace the PCB No 6362 6 9 6 HC ACK Code Error 6 9 7 HC Transmission Count Error 6 9 8 HC Reception Count Error Monitor Timing During data transmission Monitor Method Monitors RS
183. ing Description 461 2655 0 Sla 663 0209 1 663 0402 6 663 0407 4 663 0405 7 663 0211 9 264 0801 7 921 0351 8 663 0210 5 663 0403 0 663 0408 8 663 0406 1 541 1352 1 663 0213 6 663 0206 0 663 0207 3 833 3895 6 365 2231 4 344 5471 7 663 0212 2 10 11 13 14 500 2 RINSE BOTTLE ASSY 5 2L RINSE BOTTLE ASSY CA 5H 5L RINSE BOTTLE ASSY CA 5H 2L EU UK RINSE BOTTLE ASSY CA 5H 5L EU UK TRAP CHAMBER COMPLETE ADAPTOR ID 23 G PAPER THERMAL F1 2 5 BOX WASTE BOTTLE ASSY CA 5H 2L WASTE BOTTLE ASSY CA 5H 5L WASTE BOTTLE ASSY CA 5H WASTE BOTTLE ASSY CA 5H 5L EU UK PUSH VIAL PV 10 SAMPLE TUBE SPACER 13 PHI REAGENT RACK ASSY REACTION TUBE TRASH BOX SAMPLE RACK NO 3 W HOLDER 55 VIAL SPACER NO 1 FIXING SCREW TL 233 SAMPLE TUBE SPACER 10MM DIAMET Included in supply parts of CA 550 560 Included in supply parts of CA 510 520 530 and 540 CA 500 Z Axis Position Adjustment Tool PM Code No Drawing Description 031 0171 4 ECR301K074 ECR303C012 TB200408 CA 500 Series S M CA 5H Z AXIS POSITION ADJUSTMENT TOOL PM A 1 33 Revised February 2004 TB200408 80700581 ooz be i v vc 0 6 ONS2d S926
184. ing Tube No 50 C Connecting Tube No 3 9 Nipple No 123 CA 500 Series S M 2 1 Revised December 2001 8 2 2 HYDRAULIC SYSTEM OPERATION 2 2 1 Structure The hydraulic system consists of the volumetric syringe for volumetric dispensing of samples or reagent the filling line using the pressure pump and solenoid valve and the drain line using the vacuum pump 2 2 2 Operation 1 Outline of Hydraulic System Operation This system s filling and draining are operated by pressure created by the pressure pump and vacuum pump in the system Therefore the pressure is applied to the rinse bottle and the vacuum is applied to the waste bottle a Filling line A constant pressure is applied to the rinse bottle The valve connected to the line opens to feed rinse solution 6 Drain Line The drain line is released to the atmosphere at the rinse cup The vacuum pump operates only when the vacuum to aspirate the waste into the waste bottle The vacuum is not monitored Instead instrument checks if the liquid level becomes abnormal when the sample probe is moved to the Probe Rinse Cup inside if liquid is not drained properly the drain error occurs 2 Analysis Starting Operation a Rinsing at Analysis Start The sample probe moves to the Probe Rinse Cup outside to detect the syringe home position The probe moves into the Probe Rinse Cup inside to remove remaining liquid on the probe tip The probe moves to rinse solution position to as
185. ion detection point can be set every 196 within the range of 2 to 80 enabling the data calibration 2 External compensation Function The measured data is corrected with the linear equation 10 Required Volume of Plasma and Reagent The required sample amount for each parameter and the required volume of reagent for the measurement of one sample are shown below Unit in uL 2 APTT 3 Citrated Plasma 15 Plasma Plasma u s Veronal buffer CA Series Complex Factor HPT II V X Gwaed Pisma Continues to the next page CA 500 Series S M 1 7 Revised December 2001 8 Continued from the previous page Sample Reagent Quantity 8 VII IX XI XII PC c Citrated Plasma Protein C Deficient Plasma Protein C Activator 0 9 10 BXT 11 Lat La2 12 AT3 APL 33 1 5 Plasmin Substrate 13 33 14 Pig Citrated Plasma Owren s Veronal buffer Streptkinase Reagent 15 15 16 Hep 7 DDP AdDD 18 DD 19 SFDP 20 in 800 nm analysis Latex Test BL 2P FDP Diluent 66 PFDPDiuen 21 in 575 nm analysis Latex Test BL 2 P FDP Diluent 66 _ Additionally approximately 6 mL of distilled water and approximately 212 uL at the maximum of rinsing solution CA CLEAN l are required for rinsing per test CA 500 Series S M 1 8 Revised December 2001 8 1 4 3 Functions Sample Tube
186. is failed if not the electronic circuit is failed The pressure pump turn ON or OFF at the pressure 250 g cm If the pump does not start operating even when the cap of rinse bottle is removed the pump or its drive circuit is failed Measure voltage at the connector of pump by the DVM If AC 100 V x 15 is displayed the pump is failed if not the drive circuit is failed 141V peak 141V peak Figure 6 1 1 Normal Oscilloscope Wave CA 500 Series S M 6 1 Revised December 2001 8 6 1 2 Monitor Timing At time of rinse sequence is started and the sample probe has moved to the rinse cup Monitor Method The liquid sensor checks the error when rinse liquid has collected in the rinse cup CA 500 s Action Emergency stop 1 Probable Cause 1 The cap of waste bottle is removed SV failure Vacuum pump failure Perforations pinhole in the hydraulic line Drive circuit failure oF C5 The waste bottle is not connected 2 Confirmation by the Operator 1 2 Properly connect the tube Securely tighten the bottle cap 3 Confirmation by the Service Engineer 1 2 The vacuum pump operates only in rinse sequence When the pump is operating and waste is not flowed tubing or SV might be failed When the pump does not operate the pump or its drive circuit is failed Measure voltage at the connector of pump If AC 100 V 15 is displayed when the pump is operating
187. l Assy 1 2 Code No Drawing Description Qty per ERR Em Unit 663 0168 5 1 OPERATION PANEL ASSY 1 228 3754 7 1 LCD LRHBJ3431A 1 663 0172 1 2 PRINTER ASSY 1 662 0228 4 3 PCB NO 9265 1 662 0289 1 3 PCB NO 9303 1 INVERTER INV 5 281 226 1 5 PRINTER FTP 421MCL001 1 PCB No 9303 developed for the 550 560 is compatible with all CA 500 series analyzers Therefore PCB No 9265 will be replaced by PCB No 9303 when current stock is depleted TB200203 14 ECR303C033 ECR304C035 CA 500 Series S M A 1 25 Revised April 2004 ECR303C033 ECR304C035 500 2 2 500 Series S M A 1 26 Revised December 2001 8 500 2 2 Drawing Description 663 0168 5 1 OPERATION PANEL ASSY 1 663 0170 3 1 OPERATION PANEL BASE ASSY 663 0171 7 2 EMERGENCY STOP SW ASSY 662 0228 4 3 PCB NO 9265 663 0169 9 4 VR ASSY CA 500 Series S M A 1 27 Revised December 2001 8 CA 500 Rear Panel for Bottles lt O LO 2 lt O m t CO 2 lt ww C 2 lt CN O lt O 5 c Q x lt CO 9 a OQ gt B O CO LL 191
188. ld cover Select channel 1 by using Channel Change key select Low Gain by using Sensitive key and select Offset position by pressing T or 4 key Press Auto Adjust key to start the automatic offset adjustment and when the adjustment is completed the alarm sounds Change Gain to PT Gain and enter Offset value manually in executing Step 3 Press and keys or Manual Entry key to adjust manually Execute Steps 1 to 5 for channels 2 to 4 High Sensitivity Adjustment Gain Adjustment Insert the heated high sensitivity scattering stick labeled usually as 750 into the detector well to be adjusted CH1 to 4 Close the light shield cover Select channel 1 by using Channel Change key select High Gain by using Sensitive key and select Gain position by pressing 1 or 4 key Press Auto Adjust key to start the automatic gain adjustment and when the adjustment is completed the alarm sounds Execute Steps 1 to 5 for channels 2 to 4 CA 500 Series S M 4 6 Revised December 2001 3 Low Sensitivity Adjustment Gain Adjustment Insert the heated low sensitivity scattering stick labeled usually as 430 into the detector well to be adjusted CH1 to 4 2 Close the light shield cover 3 Select channel 1 by using Channel Change key select Low Gain by using Sensitive key and select Gain position by pressing 1 or 4 key 4 Press Auto Adjust key to start the automatic ga
189. lect 5 Move the cursor to Reagname pos 5 and press Select Reagent The screen for selecting a reagent will appear Move the cursor to DD B and press Select 6 Move the cursor to Reagname pos 7 and press Select Reagent The screen for selecting a reagent will appear Move the cursor to DD L and press Select 7 Press Return Fix to save parameters CA 500 Series S M 5 36 Added October 2003 ECR303G037 SECTION 6 ERROR MESSAGE To Cover 6 1 6 2 6 3 6 4 6 5 6 6 6 7 6 8 sS ile EONS ME m 1 PressurePumpENWoOPu UU LUZ 1 0 1 2 ino 2 Temp rature 6 2 1 Temperature Error High Incubator Temperature Error Low Incubator 3 6 2 2 Temperature Error High Detector Temperature Error Low Detector 4 6 2 3 Temperature Error High Cooler Temperature Error Low Cooler 5 6 24 Temperature Error High Room Temperature Error Low Room 6 6 2 5 Temp Sensor 6 Co L uu u E E 7 Oal Waste Boue 7 6 3 2 Replenish RINSE REAGENT 7 KOLOR
190. led avoid direct sunlight dust vibration and acid vapors 1 6 2 Reagents to be used PT APTT Pathromtin SL Dade Actia Activated Cephanloplastin Reagent Dade Actia FS Activated FTT Reagent ClottingFactorll Deficient Plasma Clotting Deficient Plasma LA1 Screening Reagent LA2 Confirmation Reagent CA 500 Series S M 1 14 Revised December 2001 8 1 7 Check Instrument Preparation Start Analysis Result Output End Analysis Shutdown Power OFF CA 500 Series S M Check the rinse solution distilled water to make sure that the analyzer is ready for operation Turn the instrument power ON 30 minutes before the analysis Dissolve reagents 30 minutes before the analysis Set the reagents to the reagent holder Execute the quality control to check the instrument condition oet the sample to the sampler Enter sample orders to be analyzed Press the Start key to start analysis The analysis results will be displayed on LCD and printed out on printer paper Remove the reagents and the sample Execute the daily maintenance for the next analysis Rinse the pipette and turn the instrument power OFF Revised December 2001 8 SECTION 2 HYDRAULIC MECHANICAL SYSTEMS To Cover 2 1 22 HYDRAULIC SYSTEM OPERATION u Ju u uu ullu ap Sud acs
191. left center of the screen If not change to 28 dust by using Pos and Pos keys Move the catcher to the setting position by using XY TEST key Use 1 lt and gt keys to adjust Y direction to a center of the waste position mark and the reaction tube Adjust X direction at the panel side of the reaction tube trash Reaction Tube Trash Position Mark _ Reaction Tube Trash Figure 4 3 25 XY Direction Adjustment Press Z ADJUST key to descent the catcher Use 1 4 4 gt Catcher UP and Catcher DOWN keys to adjust the catcher position so that Z pulse to become 13 pulses approx 1 mm above the reaction tube trash panel Adjust Y direction to the center of the waste position mark and the reaction tube Adjust the reaction tube position in X direction to touch the panel side of the reaction tube trash Splash Prevention Sheat Z position 1mmxz13Pulse Heaction Tube Trash Touching Reaction Tube Figure 4 3 26 Z Direction Adjustment Press Z TEST key to return to the home position and descent the catcher Verify that the reaction tube to enter smoothly into the reaction tube trash Press Z TEST key to descent the catcher Use Tube Free and Tube Catch keys to verify that the reaction tube to enter smoothly into the reaction tube trash 10 When the adjustment is completed press XY ORG key to return pipette head to the home position CA 500 Series S M
192. lel Push it in until the lock guide arms fit in the table lock of the CA 500 main unit As you push it the sampler will feel heavier but keep pushing little by little CAUTION The table lock is only 1 mm apart from the lock guide arms n pushing take care not to allow the lock guide arm to contact the under panel C V In Z Wi fee Figure B 26 Table Lock amp Lock Guide Arm Table Lock B 16 Revised December 2001 8 3 Connect the connector and put it in the duct 4 A S E Figure B 27 Connecting the Connector 4 Attach the duct cover The duct cover should be attached so that it will cover the outlet for the cable of the sampler with ID bar code scanner Q X os Cover Figure B 28 Attaching the Duct Cover 5 Repeat pushing in and pulling out the sampler with ID bar code scanner several times 6 With the sampler pulled out in parallel fully tighten the screws that were temporarily tightened before 7 Make sure that the sampler with ID bar code scanner will slide in and out smoothly 6 X Attach the left side panel of the CA 500 main unit CA 500 Series S M B 17 Revised December 2001 8 CA 500 Series S M Check the Sensor Status and Locking Function Turn ON the power Change the Barcode Scanner setting to connected Refer to Operator s Manual Chapter 10 5 Devices to be connected for more detail Select Sensor Status by selecting Special Me
193. lem is occurred on the program of the host computer 2 Confirmation by the operator 1 Register the Work List in the host computer correctly 3 Confirmation by Service Engineer The same as above 2 CA 500 Series S M 6 33 Revised December 2001 g 6 10 QUALITY CONTROL AND STANDARD CURVE ERRORS 6 10 1 QC Limit Error Monitor Timing When analyzing QC data in QC mode Monitor Method Monitors the Control Limit and actual QC data CA 500 s Action Warning 1 Probable Cause 1 QC analysis result exceeded the Upper or Lower Limit of the preset range 2 Confirmation by the operator 1 Check whether control plasma has been expired or not 2 Check the storage of control plasma 3 Confirmation by Service Engineer The same as above 2 6 10 2 QC Limit Error STOP Monitor Timing When analyzing QC data in QC mode Monitor Method Monitors the QC Limit Stop CA 500 s Action Analysis stop 1 Probable Cause 1 QC analysis result exceeded the Upper Stop or Lower Stop Limit of the preset range 2 Confirmation by the operator 1 Check whether control plasma has been expired or not 2 Check the storage of control plasma 3 Confirmation by Service Engineer The same as above 2 6 10 3 Set more than two points Monitor Timing When preset the standard curve Monitor Method Monitors the number of preset point of standard curve and actual analysis points CA 500 s Action Warning 1 Probable Cause 1 The number of point of s
194. light 3 11 2 Setting and Adjustment Setting and adjustments are not necessary 3 11 3 LED and Test Point There are no LEDs or test point 3 12 PCB No 9260 X RELAY X Axis Relay 3 12 4 Function This PCB is used for the signal relay and the X Axis Home Position Sensor signal relay to PCB No 2134 Y Z RELAY via FFC Flexible Flat Cable 3 12 2 Block Diagram X Axis Home Position Sensor 2 _ PCB No 6362 MAIN PCB No 6373 MAIN 2 to PCB No 2134 Y Z RELAY Signal Relay to PCB 2157 Y Z RELAY2 PCB No 4086 PS Figure 3 16 PCB No 9260 Block Diagram 3 12 3 Settings and Adjustment Setting and adjustments are not necessary 3 12 4 LED and Test Point There are no LEDs or test point 3 12 5 Assembly Drawing Figure 3 17 PCB No 9260 Assembly Drawing CA 500 Series S M 3 24 Revised December 2001 3 13 No 9263 LCD Contrast Volume 3 13 1 Function This PCB is the board to mount the volume for the LCD Contrast 3 13 2 Setting and Adjustment Setting and adjustments are not necessary 3 133 LED and Test Point There are no LEDs or test point 3 14 9264 2 RELAY Z Axis Relay Z Axis Home Position Sensor 3 14 1 Function This PCB is used for the Mixing Motor signal relay Tube Catch Sensor signal relay Z Axis Home Position Sensor signal relay and Z Axis Motor relay 3 14 2 Block Diagram Signal Relay to Stirrer Motor Signal
195. mple was being analyzed 2 Detected coagulation curve shows Reanalyze the sample to make Slight Coagulation extremely small change comprehensive judgment taking sample reagent etc into account 4 Coagulation did finish within Reanalyze the sample to make Analysis Time preset detection time or within Auto comprehensive judgment taking sample Over Extension Mode detection time reagent etc into account Or conduct another test with prolonged detection time ERROROO08 Curve shows a drop in some area Coag Curve Error 2 Curve shows too steep in some areas As buffer was cool clotting time was extended by the influence of air bubbles Fbg ERROROO16 Turbidity was too high to analyze Reanalyze the sample by pre dilution Turbidity Level Over 2 Clotting could not be detected Reanalyze the sample after checking No coagulation samples and reagents storage status blood collecting method etc for any errors and make comprehensive judgment ERROROO64 Due to any problem before photo Reanalyze the sample after preparing Measurement detection such as insufficient sample required amount of plasma Error plasma instrument error insufficient reagent Mechanical Stop Switch operation analysis could not be done The detection time at 5090 point is Reanalyze the sample after checking Range Over exceeding the preset time i e samples and reagents storage status
196. n 9 Move sample cup to the sample rack No 10 10 Press Pos key to select the setting position 2 blood 10 11 Execute Steps 3 to 8 12 Move the sample cup to the blood_stat position 13 Press Pos key to select the setting position 3 blood_ stat 14 Execute Steps 3 to 8 CA 500 Series S M 4 14 Revised December 2001 15 The confirmation screen will be displayed by pressing Quit key Sysmex Ready IP Y Replace Rack YES Mecha Position RENEW SETTING Cancel Continue Figure 4 3 6 Confirmation Screen 16 When pressing FIX key new position adjustment data will be printout and return to adjustment selection screen 3 Pipette Lower Limit Adjustment When FIX key is pressed to complete adjustment 25 pulses are added to Z pulse setting value and the value is automatically set as the pipette lower limit Large value should be set as the pipette lower limit when executing Z adjustment so that the probe can seek a liquid surface at the lowest point Be sure to set water inside the tube when setting large value manually as Z pulse If not it may cause the pipette to crash at the bottom of the tube or the motor to be mis adjusted by the pulse beyond the limit 1 Press Pipette Bottom key to display Manual Entry Screen The pipette lower limit will be reverse displayed and manual change is available y Replace Rack YES Mecha Position Probe Crash Senser Liquid Senser Old New
197. n 4 1 for the procedures N Mixing Motor Driving Power Adjustment VR101 is provided for the adjustment of mixing motor driving power however it is adjusted and fixed at shipment The below is for reference only 1 Connect the voltmeter between TP101 and frame GND 2 Adjust VR101 so that the voltage when rotating the mixing motor becomes 1 05 0 02 V 3 Fix VR101 with paint lock CA 500 Series S M 4 32 Revised December 2001 4 5 1 2 LED and Test Point Letters LED Color on PCB 1 LED Reagent Cooler Unit D403 Lit while power of the thermo module is ON Probe Unit D402 Lit while the heater is ON Detector Block D401 Lit while the heater is ON 2 Test Point Mixing Motor Voltage Adjustment Verify CPU Clock GND Verify A D Converter Reference Voltage for Temperature Control Analog GND Verify A D Converter Reference Voltage for Detector Signal Analog GND Verify Pressure Sensor Analog Output 4 5 1 3 Assembly Drawing TP201 TP202 MAIN DP0173C D403 D401 D402 VR502 gt VR501 CN101 CN104 TP101 503 501 TP401 TP402 Figure 4 5 1 PCB No 6362 Assembly Drawing CA 500 Series S M 4 33 Revised December 2001 4 5 2 4086 PS Power Source Motor Driver 4 5 2 1 CA 500 Power Supply System Check Check the voltages for each switching regulator and PS Board PCB No 4086 following the procedure below 1 sure that the Mai
198. n Adjustment Procedure of Catcher 17 c tube 1 Adjustment Parameter Catcher Position XYZ pulses of Reaction Tube Rack Summary Adjust the catcher position of the reaction tube rack by setting the reaction tube to the catcher Adjust 3 positions for each two separated reaction tube rack Standard Position X direction 5 pulses to the left of the line where the left surface of the reaction tube when descended agrees the interior surface of the reaction tube rack Y direction The center of the catcher agrees the center of the reaction tube when the reaction tube is descended Z direction 5 pulses above the line where the bottom of the reaction tube agrees to the bottom of the reaction tube rack The lower edge of the reaction tube brim should be aligned with the upper surface of the lower catcher part 1 XYZ Adjustment Place the reaction tube to the catcher Verify that the 17 c tube 1 is shown on the left center of the screen If not change to 17 c tube 1 by using Pos and Pos keys Move the catcher to the setting position by using XY TEST key Use 1 V lt and gt keys to adjust the reaction tube placed to the catcher to become the center of the reaction tube rack hole Press Z TEST key to descent the catcher Press Tube Free and Tube Catch keys to release and catch the reaction tube a Y direction Use T and keys to adjust the center of the reaction tube agrees the ce
199. n Unit Power of CA 500 is turned OFF 2 Disconnect the following connectors to be free from any load CN101 CN104 on MAIN BOARD PCB No 6362 CN2 on PRCN1 PCB No 6350 3 Turn the CA 500 Main Unit power OFF 4 Make sure that the voltage on each switching regulator and PS Board PCB No 4086 shows the output voltage in Table below There is no adjusting point 5 Turn the power switch of the CA 500 Main Unit OFF and connect CN101 CN104 on Main Board PCB No 6362 with CN2 on PCN1 PCB No 6350 The other side is connected to TP1 GND 24 12 V 0 5 V 5 V 0 2 V 5 V 0 2 V 15 V 0 6 V 15 V 0 6 V 4 5 2 2 LED and Test Point 1 LED Letters LED Color on PCB Liquid Surface Sensor LIQUID 7 Red Lit when the liquid surface is detected Probe Crash CRASH D8 Green Lit when the probe crashes These LEDs turn OFF by the RESET signal P RES 2 Test Point TP1 GND TP2 Analog Signal of Liquid Surface Detection for checking TP3 Comparator Output Signal of Liquid Surface Detection for checking CA 500 Series S M 4 34 Revised December 2001 SECTION 5 SERVICE PROGRAM To Cover 5 1 Service Mode 5 1 5 1 1 Starting and quitting the Service 5 1 5 1 2 5 1 52 ET
200. n b 000 0 0 0 00 000 000 0 0 000 Polynomial Dimension 3 3 3 3 3 3 3 StatTime 0 o o o o o 0 o EndTime 0 o o o o o o Minimum SearchWindow 0 o o o o O SearchWidthforPreevaluation 0 0 o o o Upper max Evaluation Offset 0 0 o o o o O o 0 0000 Min Regression Time 0 o o o o O 0 0 5 3 Immunoassy ae ae me 20 _ Reagent ooo ooo o0 oo oo o0 0 ooo StatTima2 70 70 80 80 9 999 Polynomial mension 3 3 3 3 3 3 T 3 3 StatTime 3 3 o o o o o o A A2 10 18 o o o o o Minimum 3 2 o o o Variable Time of Evaluation OFF OFF OFF OFF OFF SearchWidthforPreevaluation 50 50 o o o o o o Upper max Evaluation Offset 60 6 _ 0 0000 Min Regression Time L LX Mixing Time for Sample 05 05 05 05 05 05 05 05 Mixing TimeforReagent 95 os 08 05 05 05 05 os 3 tt Calbaionb 0 o o o o o 0 High Accurate
201. n is operating If not inside temperature rises causing it impossible to keep the detector at 15 C 2 the cooling fan is failed the temperature cannot be kept at 15 Suspect Part Test Points Expected Value Temperature sensor Temperature sensor connector pin 1 green 5 V and pin 3 black GND Temperature sensor connector pin 2 white 0 10 V to 0 20 V and pin 3 black GND CN115 PCB No 6362 pin 1 and pin 3 GND CN115 PCB No 6362 pin 2 and pin 3 GND approx 0 15 V cooler temp C 0 01 V 0 02 V Pertier connector pin 1 and pin 2 12 V 10 3 When the voltage between pin 4 and 5 of CN8 PCB 4086 shows 12 V the harness of Peltier heater unit is failed Otherwise the PCB No 4086 is failed CA 500 Series S M 6 5 Revised December 2001 8 6 2 4 Temperature Error High Room Temperature Error Low Room Monitor Timing When READY 1 minute interval During analysis No monitoring Monitor Method A D converter reads the thermal sensor data installed at the upper fan motor as follows Temperature error when exceeds the range 10 0 40 0 C 1 Probable Cause 1 Room temperature became outside the range between 15 35 C 2 Check whether any obstacle is in front of the ventilation ventilator or the ventilator is too close to the wall 4 Failure of PCB No 6362 5 Failure of main unit fan 2 Confirmation by the Operator 1 Confirm room temperature by checking temperature displayed on the main u
202. nal to PCB No 6373 MAIN 2 _ 2 to No 6362 MAIN Probe Crash Signal lt PCB No 6373 MAIN 2 Probe Crash SW Lowpass Flip Flop Filter Y Axis Home Pos m Y Axi i to PCB No 6362 MAIN adis Y Axis Home Pos Sensor Signal to PCB No 6373 MAIN 2 Z Axis Motor to PCB No 9264 Z Home Sensor Signal relay Z RELAY Mixing Motor to PCB No 9260 X RELAY Tube Catch Sensor Figure 3 6 PCB No 2134 and 2157 Block Diagram CA 500 Series S M 3 8 Revised December 2001 g 3 5 3 Circuit Explanation 1 Liquid Surface Detection Circuit 1 Oscillator X1 Q1 etc Colpitts Oscillator Circuit using ceramic oscillator X1 oscillates a wave form of 400 kHz 2 Limitter D1 Diode D1 clips the 400 kHz wave form to 1 2 Vp p 3 Amplifier 1 U1 Non inverting amplifier amplifies the 400 kHz wave form and adds the 400 kHz signal to the probe 4 Buffer Q2 3 4 This circuit receives signal of probe capacitance change It also imposes the guard shield at the same potential with the probe low impedance 5 Detection Circuit D5 C11 R15 400 kHz wave form is peak detected 6 Highpass Filter Q6 R18 C13 The wave form after de modulation is differentiated and only the differential part is extracted T Amplifier 2 U2 Differentiated wave form is amplified 8 Comparator Circuit 1 and 2 U3 Liquid surface signals of touching and detaching t
203. ncy stop 3 7 2 Block Diagram w m m m m m m m mom ou Ml gu as d Up Switch 1 ead Up Switc LL vc CNS voc 24V Sensor CNG Phase A Stepper exe Motor y pA eee Driver p otor oO st D 2 E EN Tima I iL Time iMonitorn to cut off m the power T T Pa 1 REI Pat Po Reset DATA J CLOCK Power Supply Unit Figure 3 10 PCB No 6350 and 6375Block Diagram CA 500 Series S M 3 15 Revised December 2001 3 7 3 Setting and Adjustment Setting and adjustments are not necessary 3 7 4 LED and Test Point There are no LEDs or test point 3 8 PCB No 6362 MAIN CPU I O Motor Control Temperature Control A D PCB No 6373 MAIN 2 CPU I O Motor Control Temperature Control A D New CPU board is mounted in following instruments CA 510 S N A1300 and thereafter CA 520 S N A1018 and thereafter CA 530 S N A1805 and thereafter CA 540 S N A3405 and thereafter CA 550 S N A1001 and thereafter CA 560 S N A1001 and thereafter 3 8 1 Function This PCB s functions are CPU I O Motor Control Temperature Control and A D etc 1 CPU 2 Cl
204. nge i I L Check NON valve OUT ID unit KA T CN105 19 115 118 120 CN114 Home pos QVI di Detection SUA CN110 RS 232C Home Rinse Reader Detection _ CN112 MAIN BOARD lli Fh PCBNO 6362 CN111 BOARD 6373 OUT J 7 CN102 NO 7015 f IN Switch CN107 SV1 V J CN104 CN108 Ferrite Core CN106 p COS Lithium battery ids re LH xt Int Cwe PCBNO 4086 E Main Unit Fan SW Reg CNB A DC2AV Power Source Display ii Sid em SW Reg PCBNO 6375 Section PR RELAY DC12V CN13 CN2 CN4 CN5 CN6 CN3 Built in SW Reg Printer CN4 Contrast N CN12 Adjust 5 CN8 FUSE AC100V Power SW eno 9236 i CN6 Certo CN10 N Invertor CN2 N Wase E Transfomer AC 16 5V CN15 N Emergency CN3 I Switch N SE E SPLIT N d PCBNO 9265 M ar PCBNO 9303 Z FG CA 500 Wiring Tubing Diagram TB200408 7 1 APPENDIX PARTS LIST To Cover Contents Page CA 500 Main Unit Chassis Assy 1 2 A 1 2 CA 500 Main unit Chassis Assy 2 2
205. nge is 20 30 2 Connectthe Pressure Gauge with resolution of more than 28 g cm which can measure the pressure of 300 g cm to the pressure line black on the rear panel 3 Adjustment procedure 1 Start Service Mode 2 Select Special Operate gt Service gt Adjust gt Adjust of Pump Adjust of Pomp Low Gain A DData 455 Offset 242 g cm Gain Figure 4 1 4 Adjust Pump Screen 3 Disconnect the tube at the pressure side the black marking line on the rear panel to release the pressure sensor so that the pressure sensor shows the atmospheric pressure 4 Offset the cursor by using T and keys 5 Adjust the offset value by using and keys so that the pressure gauge shows 1 g cm When the offset value is lowered A D value also becomes lower Actually there is a fluctuation of 0 4 for the value therefore adjust it so that it shows the value which approaches 0 most 6 the pressure gauge to the pressure line on the rear panel 7 Move the cursor to the by using T and 4 keys 8 Adjust the gain value by using and keys so that the pressure gauge value adjusted 250 g cm by the procedure described 4 1 1 Adjustment of Pressure Detector Circuit agrees with the displayed pressure value on CA 500 The difference between the pressure gauge value and CA 500 displayed value should be adjusted with
206. nit 2 Provide sufficient space around the ventilator 3 Confirmation by Service Engineer 1 Check the main unit fan is operating If not inside temperature rises Suspect Part Test Points Expected Value Temperature sensor Temperature sensor connector pin 1 green 5 V and pin 3 black GND Temperature sensor connector pin 2 white approx 0 25 V and pin 3 black GND room temperature x 0 01 V 0 02 V 5 V CN115 PCB No 6362 pin 8 and pin 9 GND approx 0 25 V room temperature x 0 01 V 0 02 V 6 2 5 Temp Sensor Error Position Monitor Timing Everytime Monitor Method Error is monitored by ACK BUSY signal time out with temperature control CPU on PCB No 6362 or PCB No 6373 and Main CPU CA 500 s Action Warning 1 Probable Cause 1 Failure of PCB No 6362 2 Confirmation by the Operator 1 Confirm temperature by checking temperature displayed on the main unit 3 Confirmation by Service Engineer 1 Confirm temperature by checking temperature displayed on the main unit 2 When the temperature is not displayed or 99 9 is displayed the PCB 6362 is failed CA 500 Series S M 6 6 Revised December 2001 8 6 3 CHAMBER ERRORS 6 3 1 Waste Bottle is full Monitor Timing At time of analysis start before sample dispensing Monitor Method The float switch in the waste bottle monitors the waste CA 500 s Action Interruption 1 Probable Cause 1 The waste bottle is full 2 T
207. nter of the catcher Figure 4 3 17 Y Direction Adjustment CA 500 Series S M 4 22 Revised December 2001 b X direction Use lt and gt keys to adjust the horizontal position of catcher The catcher once ascends and then descends by pressing Z ADJUST key Adjust the reaction tube position in X direction to touch the left part of the inner wall of the reaction tube rack by repeating this operation Catcher Heaction Tube Rack Figure 4 3 18 X Direction Adjustment c Zdirection Use Catcher DOWN key to confirm the position where the reaction tube hit the bottom of the reaction tube rack Touch around the reaction tube rack hole to confirm the vibration of the hit or touch the reaction tube to verify that there is no more play Press Catcher UP key for 5 times Press Z Adjust key for 2 or 3 times to confirm that the reaction tube does not hit the bottom of the reaction tube rack The Z position can be also adjusted by using Tube Catch key and Tube Free key and aligning the lower edge of the reaction tube brim with the upper surface of the lower catcher part Lower Edge of the Reaction Tube Brim Upper Surface of the Lower Catcher Part Figure 4 3 19 Z Direction Adjustment 7 Press Tube Free and Tube Catch keys to verify that the reaction tube to be caught and released smoothly 8 When the adjustment is completed catch the reaction tube and return the catcher to the Z home position b
208. ntrol Expiry Monitor Timing When starting analysis of QC order Monitor Method Monitor QC settings by the software CA 500 s Action Warning is displayed 1 Probable Cause 1 Failure to preset expiry date of control plasma or wrong setting 2 Confirmation by the operator 1 Preset expiry date properly at QC settings 3 Confirmation by Service Engineer The same as above CA 500 Series S M 6 28 Revised December 2001 g 68 MEMORY ERRORS 6 8 1 Invalid Settings Monitor Timing At time of updating the settings Monitor Method CA 500 s Action No updating 1 Probable Cause 1 Input data exceeds the limit 2 Confirmation by the operator 1 Change settings after confirming appropriate settings and conditions 3 Confirmation by Service Engineer The same as above 6 8 2 Stored Data Error Monitor Timing When the power switch is turned on Monitor Method Monitors CHECK SUM of stored data CA 500 s Action Deletion of error data 1 Probable Cause Refer to below 3 2 Confirmation by the operator 1 Turn the power switch off and on again 3 Confirmation by Service Engineer 1 The PCB No 6362 or backup battery is faulty 6 8 3 QC Data Error Monitor Timing When the power switch is turned on Monitor Method Monitors CHECK SUM of each file of QC data CA 500 s Action Deletion of error data 1 Probable Cause Refer to below 3 2 Confirmation by the operator 1 Turn the power switch off and on again
209. nts Set key Press to perform the test Return key Press to quit the test operation and to return to the Test Menu screen To cancel power consumption test operation Press Return key to stop the operation then the power consumption test setting screen will appear This program does not stop automatically You must press Return key when you stop this program CA 500 Series S M 5 11 Revised December 2001 g 5 5 4 Verify reagent pipette incubation operation 1 Press Special Operate Service Test Menu Reagent Temp keys to start then the following screen will be displayed IP poem Replace Rack YES Reagent Temp Volume 7 8 9 100 uL 4 5 6 1 1 2 3 0 Enter Quit Figure 5 5 5 Reagent Temp Screen 2 To verify Reagent Incubation operation Pour 50 uL of distilled water into a reaction tube Set a thermometer into the water Then put it into the incubation well 6 Verify that the distilled water temperature in the reaction tube 1 37 1 Put the sample cup containing distilled water in reagent holder 1 Set the dispensing volume using numeric keys at 100 pL default value Press Enter key to set eventually the input volume to 100ul Remove the thermometer from reaction tube and press Set key to perform the heating operation After the reagent nozzle is disp
210. nu Special Operate System Tests AE System Test AE Sensor Status Make sure that Sample Table status changes from to when Sampler position changes from in to out IN position 8 OUT position O Make sure that Sampler cannot be pull out when Lock key is pressed on Sampler s IN position Make sure that Lock key changes to Unlock when Lock key is pressed Make sure that Sample can be pulled out when Unlock key is pressed Check the Reading Function 1 2 Select Sensor Status by selecting Special Menu gt Special Operate gt System Tests gt System Test gt Barcode Scanner Make sure that bar code scanner moves to the home position when Ret ORG key is pressed Make sure that ORG Sensor status changes from O to 8 when the bar code scanner reaches to the home position There is a case that ORG Sensor status changes from O to and changes to O in very short time This is also normal function oet 10 sample test tubes with bar code label in the sample rack Perform reading test by pressing CONTINUE key Refer to Operator s Manual Chapter 8 5 Barcode Scanner Make sure that all labels are read without an error Adjust the Pipette Position for the Sampler 1 Perform pipette position adjustment Refer to Service Manual 4 3 4 Position Adjustment Procedure of Pipette 1 blood 1 2 blood 10 and 3 blood stat B 18 R
211. ny mis positioning b Replace the catcher 2 When an error occurs though a tube is caught a Ifthe tube detection sensor is dirt wipe it clean by alcohol Suspect Part Test Points Expected Value Tube Detection CN2 PCB No 9264 pin 3 GND and pin 2 o V gt 0 V when a tube is detected oensor CN1 PCB No 9264 pin 13 GND and pin 8 5 V gt 0 V when a tube is detected CA 500 Series S M 6 17 Revised December 2001 g 6 5 5 Probe Crash Monitor Timing When the probe descends Monitor Method Micro switch incorporated in the probe holder monitors Probe crash CA 500 s Action Emergency stop 1 Probable Cause 1 Reagentis absent or insufficient in reaction tube or sampler cup in reagent rack or in sampler cup Plasma sample is absent or insufficient in reaction tube or sampler cup in reagent rack or in sampler Probe is obstructed to descend Mis positioned probe Failure of probe Failure of PCB No 9264 Failure of PCB No 2134 Failure of Y Z relay harness Failure of PCB No 9260 Failure of X axis wiring cord 10 Failure of wiring cord flat cable 11 Failure of PCB No 6362 ai 2 Confirmation by the operator 1 Place reagent and sample in required amounts 2 Remove anything that is obstructing the operation 3 Confirmation by Service Engineer 1 When probe crash has actually occurred a Correct mis positioning if it is the case b Confirm probe position for reagent sample and reac
212. o 2134 X axis wiring cord and PCB No 4086 is faulty b Turn the pulley by hand If it does not move the motor or drive mechanism is faulty 4 Failure of drive mechanism a Check for flaws on the shaft b If the shaft is free from flaws the problem is in the bushing CA 500 Series S M 6 10 Revised December 2001 g 6 4 4 Z Axis Down Error Monitor Timing When reaction tube is caught and released Monitor Method Monitoring the tube detection condition CA 500 s Action Emergency stop 1 Probable Cause 1 10 11 12 13 Drive mechanism operation is obstructed Loosened pulley of motor Failure of PCB No 9264 Failure of PCB No 2134 Defective light shield Flaws on shaft Failure on bushing Failure of PCB No 9260 Failure of wiring cord flat cable Failure of PCB No 6362 Failure of Z axis motor assembly Failure of PCB No 4086 The light shield attached to the catcher is mis positioned or defective 2 Confirmation by the Operator 1 2 3 Remowve the reaction tube Remove the obstruction in Z axis drive mechanism Turn off the power supply and turn it on again 3 Confirmation by Service Engineer 1 2 Retighten the screw of the pulley of motor If home position cannot be detected even when the drive mechanism is operated a Check whether the light shield is defective or not Suspect Part Test Points Expected Value Position sensor CN1 PCB No 9264 pin 9 GND
213. ock Generator Circuit 3 Interrupt Controller Circuit 4 Voltage Drop Monitor Circuit 5 RESET Backed up Switching Circuit 6 EEPROM WORK RAM B RAM 7 Real Time Clock 8 PRCN1 Interface 9 LCD Interface 10 Serial Interface 11 Touch Screen Interface 12 ID Unit Interface 13 MEMORY CARD Interface 14 Sensor Entry 15 DIP SW Entry 16 Detector Block Interface 17 Temperature Control Circuit 18 Pressure Control Circuit 19 Stepper Motor Control 20 Vacuum Pump Drive 21 SV Control Sampler Table Lock Control 22 Buzzer Control 23 Mixing Motor Control 24 Bus Interface CA 500 Series S M 3 16 Revised February 2004 TB200408 3 8 2 Block Diagram Constant Reference IF 20mA unen Voltage 1 Buffer for LED 4 6V B LED etector Block D A 1QBit D A 13BItA D CH1 6 Multiplexer GAIN OFFSET able Adjustment Convert il L INT 15V Volt Monitor 24V Volt Monitor Pressure Monitor Pipette 1 100 _ Gonstant Reference Thermister Circuit for Thermistor 4 6 CLOCK 4MHz AMP omparator emperature 6 3 13Bit A D ontrol CPU PIO Temperature Cooler U Sensor IC Thermister Peltie Cooler Heater Pipette Heater Control PCB 4086 PS Multiplexer UM Differencial Amplifi
214. of the Reaction Tube Brim Upper Surface of the Lower Catcher Part Figure 4 3 22 Z Direction Adjustment 7 Press Tube Free and Tube Catch keys to verify that the reaction tube to be caught and released smoothly 8 When the adjustment is completed catch the reaction tube and return the catcher to the Z home position by using 2 ORG key Move X axis 5 pulses towards to the left by pressing lt key for 5 times This is the X adjustment value 9 When completed press XY ORG key to return the catcher to the home position 10 Setting Position 24 warm 3 25 warm 4 26 comp Adjust above 3 positions in the same way CA 500 Series S M 4 25 Revised December 2001 4 3 11 Position Adjustment Procedure of Catcher 27 shake Adjustment Parameter XYZ pulses of Reagent Dispensing Position Summary Use the JIG tube for adjustment to adjust reagent dispensing position The JIG tube is the reaction tube that the 3 mm width x 15 length copper tape is attached inside The copper tape should be attached straight from the top of the flange Copper Tape Heaction Tube Figure 4 3 23 JIG Tube 1 XY Adjustment Place the JIG tube to the catcher Change the setting position to 27 shake by using Pos and Pos keys Input Z pulse 40 by selecting Enter Pulses Press XY TEST key to move XY of the pipette to the dispensing position Press Pipette 70 Step key to ascend the ca
215. on of sample rack 5 Input the dispensed volume using numeric keys between 1 and 250 LL 6 Setthe input volume by pressing Enter key 7 Press Set key to perform the dispensing operation After dispensing measure the test sample by the electric balance 8 If dispensed volume is OK press Quit key Then the screen will return to the Test Menu display CA 500 Series S M 5 10 Revised December 2001 g 5 5 3 Full Power Verify the maximum power consumption 1 2 3 Press Special Operate Service Test Menu Full Power keys to start then the following screen will be displayed Susme Ready IP y Replace Rack YES Full Power Eminty Tube 5 Warm No 1 Detect No 1 Test Stop 0 0 MODE Set RESET Return Figure 5 5 4 Full Power Screen In this test program pipette shifting syringe operation and valve opening are performed at once Before performing this operation drain water operation as described in Section 5 6 1 because there is a possibility the pipette discharges water to the incubation detector block NOTES Avoid performing this test operation for a long time e Set reaction tubes to the 1 5 21 25 31 35 56 and 60 positions DO NOT set tubes to the other positions MODE key Use to alternate the mode Full Power or RESET key Use to clear the operation cou
216. ooling Function None o Sample ID Reading Function Sample ID No can be read by the Bar Code Reader STAT Sample Measurement Function 1 The specified sample the STAT Sample Rack can be analyzed interrupting the usual analysis Within 10 minutes from the interruption by the STAT sample analysis the analysis result can be output when the single parameter is analyzed 2 Number of STAT sample One sample only Measurement Interrupt Restart Function CA 550 and CA 560 only The analyzer has the function to allow setting additional samples to the rack in process after starting a measurement and measuring them The registration of the additional samples can be made on the left side from the left end tube position for the samples already set in rack and registered for measurement CA 500 Series S M 1 9 Revised December 2001 8 10 Reagent Storage Function Reagent Storage Method otored in the reagent rack 2 Reagent holder capacity Maximum 10 kinds of reagent bottles can be set in the reagent rack Buffer and rinsing solution can also be set 3 Usable container Dade Bering s old DADE for 5 mL a sample cup can be set and also GW5 a new type of reagent bottles only for CA 550 CA 560 can be set The outer diameter of the reagent bottle should be less than 22 5 mm and also if the inner diameter is too small use the bottle adapter 4 Reagent Cooling Function Four reagents can be cooled CA 530 CA 540 5
217. or well discard 2 DO NOT leave reaction tubes on the Reaction Tube Rack to prevent malfunction T keys Use to move cursor key Use to increase value on which cursor is positioned key Use to decrease value on which cursor is positioned Set key Press to perform the tube transfer test Return key Press to quit the test and to return to Test Menu display 3 To cancel tube transfer test operation Press Cancel key to stop the operation then the tube transfer test setting screen will appear 5 5 6 Catcher Test Verify the catcher operation 1 Press Special Operate Service Test Menu Catcher Test keys to start then the following screen will be displayed S Ready IP ToU Replace Rack YES Catcher Test Tube 5 Warm No 1 Detect No 1 Test Stop 0 0 5 Return Figure 5 5 7 Catcher Test Screen 2 To verify catcher operation Set reaction tubes in the 1 5 21 25 31 35 56 and 60 position of the Reaction Tube Rack DO NOT place tubes in the other positions RESET key Use to clear the test cycle counts Set key Press to perform the catcher test Return key Press to quit the test and to return to Test Menu display 3 To cancel catcher test operation Press Cancel key to stop the operation then the catcher test setting screen will appear CA 500 Series S M 5 13 Revised
218. per side 15 Crush Sensor is fixed in the pipette cap 16 Catcher holder is fixed by two screws together with Leaf Spring Slider Base SUS Sub Plate and SUS Case 17 Catcher is fixed together with O Ring Spacer Fixing Metal SCL6 13 and O Ring in this order by two fixing screws 18 Z axis motor is fixed to Z Axis Base with the SUS plates by two screws lt gt 2 Pipette Crash Sensor SUS Case Pipette Cap ps Slider Base d Catcher Holder C Sub Plate Catcher Rubber B M Z lt Leaf Sprin pring Catcher Rubber A 2 Cord Holder Vibration Probe p cau Cord Holder Tube Sensor Light 5 T Ligh Shield Plate xil gt i O ring x 22 cam Le IL 7 SCLE B Sach g atcner SCL6 12 Spacer Mixing Motor Figure C 12 Catcher Unit Assembly CA 500 Series S M C 7 Revised December 2001 8 C 5 Operation Panel Assembly 1 Remove all the panels Disconnect PR RELAY connector 7 8 on PCB No 9265 Disconnect two relay Connectors and LCD Connector item 2 Remove two screws on the top side item 3 and four screws on the right side item 3 to pull Operation Panel Assembly toward you NN NN o SY Figure C 13 Removing Operation Panel Assembly Remove six screws on the back side of Operation Panel Assembly and you can find Printer LCD VR 4 Assembly and Eme
219. pirate CACLEAN 1 Aspirated rinse solution is kept in the probe for a certain time to rinse the probe inside This can be changed in Service Program The sample probe moves to the Probe Rinse Cup inside and the rinsing solution flows by opening SV on Rinse Cup At this time the syringe piston moves to drain the rinse solution The probe moves into the Probe Rinse Cup outside and both the Probe Rinse Cup valve and the valve on probe open to rinse the probe b Reagent Aspirating and Dispensing When aspirating sample or reagent the probe moves to a sample to aspirate lowers into the test tube detects the liquid surface then the volumetric syringe descends and aspirates the sample At this time the solenoid valve does not operate keep closed When draining the probe moves to the reaction tube in the Reaction Tube Rack to dispense the volumetric syringe ascends and dispenses the sample After that the probe moves to home position and moves to the Probe Rinse Cup inside CA 500 Series S M 2 2 Revised December 2001 8 c Probe Rinsing after Sample Aspiration The probe moves to the Probe Rinse Cup inside The Probe Rinse Cup inside valve opens to empty rinse solution from the probe Then the probe moves to the Probe Rinse Cup outside to remove a drop from the probe tip d Reagent Aspiration and Dispensing The probe which stops for cleaning after sample aspiration moves to the reagent rack to aspirate descends into the re
220. ple Cup and Test Tube with Distilled Water CAUTION If the customer uses test tube do not set the sample cup The sample probe descends insufficiently when the z axis is adjusted by a sample cup 2 Verify that the 1 blood 1 is shown on the left center of the screen If not change to 1 blood 1 by using Pos and Pos keys 3 Move the pipette to the setting position by using XY TEST key CA 500 Series S M 4 13 Revised December 2001 4 Use 7 4 lt and gt keys to adjust the pipette tip to become the center of the sample cup 15 mm Diameter Test Tube Adjust the pipette tip to become center of the sample cup 50 uL of Distilled Water Figure 4 3 5 Pipette Tip Position 5 Press Z TEST key to descent the pipette The pipette detects the 50 uL of distilled water and stops CAUTION Probe descend until probe detect liquid surface or pipette bottom pulse value When the probe stops before detecting liquid surface perform Section 4 3 4 3 Pipette Lower Limit Adjustment 6 Use 7 lt and gt keys to adjust the pipette tip to become the center of the sample cup 7 Press Z ADJUST key again to ascend and descend the pipette Verify that the pipette is placed at the center of the sample cup Z pulses will be stored as the setting value in the memory when Mecha Position adjustment is completed 8 Press XY ORG key to return the pipette head to the home positio
221. quence Water Drain Process 2 3 The confirmation message Water Drain Process 2 will appear Place a tissue or cloth on the rinsing cup to prevent water splashing 4 Select the appropriate key Set Absorbs water in the rinsing cup or tubes Approx 10 seconds When completing the Test Menu screen will return Discard the absorbed tissue or cloth Cancel Returns to the Test Menu screen without performing the water drain sequence 2 5 5 2 Dispense Volume Verify Syringe dispensed volume 1 Press Special Operate Service Test Menu gt Dispense Volume keys to start then the following screen will be displayed S Ready IP ee Replace Rack YES Dispense Volume 100 uL Volume 7 8 9 4 5 6 TUBE 1 1 2 3 PUSH OUT 0 Set C Quit Figure 5 6 3 Drain Liquid Confirmation Screen 2 To verify dispensed volume 1 In advance measure the prepared test sample by the electric balance 2 Putthe sample cup or tube containing distilled water on Sample 1 position 3 position to dispense can be selected Select either TUBE 1 or BLOOD 2 using PUSH OUT key Pressing PUSH OUT alternates TUBE 1 and BLOOD 2 4 When selecting TUBE 1 put a new reaction tube in 1 position of Reaction Tube Rack When selecting BLOOD 2 put the sample cup or sample tube containing distilled water in 2 positi
222. r 0 oor ve ra re puz rs re re rs re r8 F8 re re re ve re ve SUL TI 340 33O 40 340 340 340 340 io jO 340 330 IMVIS e 8 8 8 340 340 33O 340 440 440 340 440 34O 0 340 34O MOTS Z 661 suoneinoo uebeen 260 901 150 80 8601 o O O o o o 9 o 9 0 o o o o po o o 9 9o 9 9 9 90 90 s s t S 2 2 2 o vw o o o o o o w o oe v o v s w s o o o o o o o o S S S S S 1 m sis jeuv 2 Chromogenic Low Light Error Limit 200 200 200 200 200 200 200 200 Reagent Correlatio
223. re Adjustment Procedures 44 31 RTT 32 451 No 6362 MAIN CPU I O Motor Control Temperature Control 32 PCB No 6373 MAIN 2 CPU I O Motor Control Temperature Control A D 32 4 5 2 No 4086 PS Power Source Motor Driver 34 CA 500 Series S M Revised December 2001 SECTION 4 ADJUSTMENT 4 1 PRESSURE ADJUSTMENT 4 1 1 Adjustment of Pressure Detector Circuit 1 Verify that the ambient temperature where the unit is located is within the range of 15 35 The optimum recommended temperature range is 20 C 30 C 2 Prepare the Pressure Gauge which can measure the pressure of 0 3 kg cm in the pressure line black on the rear panel aam s ss Sanh TC JLIL VOL ipd cer Hear Panel Figure 4 1 1 Rear View 3 Adjustment procedure 1 Turn the power OFF Remove the rear panel and the dummy cover under the HOST connector Dummy Cover Figure 4 1 2 Dummy Cover Left Side View CA 500 Series S M 4 1 Revised December 2001 10 11 12 13 Connect Jumper Pin J501 of PCB 6362 or PCB 6373 to 2 Loosen and remove the rinse bottle cap carefully because the cap will be lifted up by the p
224. red on the rear panel Connect the waste bottle tube yellow to the trap chamber nipple yellow 2 Connect the level detecting float switch to the float switch connector on the rear panel Waste Float Switch Connector Rinse Float Switch Connector Trap Chamber Nipple Yellow Pressure Supply Nipple Black Waste Vacuum Nipple Green Rinse Aspiration Nipple Blue Waste Drain Nipple Red s Figure B 6 Connecting the Bottles CAUTION Even at a facility equipped with the waste channel drain system the waste bottle should be connected Also put the rinse bottle and the waste bottle at the same level as the instrument sure not to use any other tube than the furnished one otherwise the instrument s hydraulic system may fail to operate properly CAUTION e Remove the rubber tube that locks the float switch in the rinse bottle and waste bottle This rubber tube served to prevent vibration in transit D S Rubber tug CA 500 Series S M B 6 Revised December 2001 B 6 Connect Power Cord and Connection Cord 1 Connect the furnished power cord 1 Make sure the power switch is OFF at O 7 Power Connector AC Figure B 7 Connecting the Power Cord CAUTION Confirm the power switch is OFF at before routing the power cord Make sure to ground the AC outlet otherwise there is a hazard of electrical shock 2 Connect the cable to link with the host computer 1 Make sure
225. ressure inside the rinse bottle Disconnect the black marked silicone tube connected to the rear panel at the rinse bottle Connect the pressure gauge to the silicone tube Turn the power ON Adjust the VR502 OFFSET so that the pressure becomes 225 3 g cm The pressure will be increased when VR is turned to CW direction Disconnect the pressure gauge from the tube once when adjusting the pressure decreasing Remove Jumper Pin J501 Do not lose the jumper pin because it is placed on the PC board Adjust the VR501 GAIN so that the pressure becomes 275 3 g cm The pressure will be increased when VR is turned to CW direction Disconnect the pressure gauge from the tube once when adjusting the pressure decreasing Verify Steps 1 to 5 again As the VR502 OFFSET and the VR501 GAIN are related each other adjust them repeatedly until the set values are obtained by repeating Steps 1 to 5 Reconnect Jumper Pin J501 to C 1 Disconnect the tube to decrease pressure and reconnect it Verify that pressure is 250 3 g cm If pressure is not 250 3 g cm check and adjust again by repeating Steps 1 to 5 J501 2C1 VH502 VR501 Figure 4 1 3 PCB No 6362 Jumper VR Location CA 500 Series S M 4 2 Revised December 2001 4 1 2 Adjustment of Pressure Indication 1 Verify that the ambient temperature where the unit is located is within the range of 15 C 35 C The optimum recommended temperature ra
226. rgency Stop Switch inside 5 No 9265 is fixed by four screws Figure C 14 Operation Panel Assembly CA 500 Series S M C 8 Revised December 2001 8
227. rs CA 550 and CA 560 only Fbg Fbg 00 DDPI SFD and PFD are also treated as parameters and QC analysis can be performed on each parameter CA 550 and CA 560 only 3 Number of stored files 12 files for each parameter 67 files CA 550 and CA 560 only 4 Number of data points 180 for each parameter 17 Select Function 1 Measurement Mode i Random access measurement mode 5 parameters are selected out of 7 parameters 14 parameters in CA 550 and CA 560 and the five parameters are measured at random ii Programmable measurement mode All parameters are measured with changing the measurement order iii Replication mode The same sample is measured twice or more and the mean value is determined to be the measurement result However the throughput is less than half number of that of ordinary measurement Settings i Sample ID number ii Date Time Setting function for APTT heating time 2 3 4 or 5 minutes of heating time can be set Standard setting is 3 minutes and the throughput changes if other time is set 3 Output Automatic transfer or Manual transfer can be set Raw data output is available in Service mode CA 550 and CA 560 only 4 Stored data processing Displaying and printing the stored data is possible 5 Service Function For the Customer Displaying of standard curve data and setting of abnormal values range For the Servicing Personnel Service mode System tests M
228. ry 2004 TB200408 PART NO INDEX gt 663 0188 0 663 0189 3 663 0190 8 663 0190 8 663 0191 1 663 0191 1 663 0195 6 663 0196 0 663 0196 0 663 0197 3 663 0197 3 663 0198 7 663 0198 7 663 0199 1 663 0200 8 663 0200 8 663 0201 1 663 0201 1 663 0202 5 8 663 0203 9 8 663 0204 2 S ea lt R 663 0205 6 663 0206 0 663 0207 3 663 0209 1 663 0209 1 663 0209 1 663 0210 5 663 0210 5 663 0210 5 663 0211 9 663 0212 2 663 0213 6 663 0217 1 663 0217 1 663 0370 4 663 0371 8 663 0372 1 663 0373 5 663 0374 9 663 0375 2 663 0392 6 663 0393 0 663 0394 3 663 0399 1 663 0399 1 663 0400 9 663 0401 2 663 0402 6 663 0402 6 663 0403 0 663 0403 0 663 0404 3 663 0405 7 663 0405 7 663 0406 1 500 Series S M PART DESCRIPTION CATCHER ASSY TUBING ASSY PIPETTE PIPETTE ASSY CA 500 PIPETTE ASSY CA 500 PRESSURE PUMP ASSY PRESSURE PUMP ASSY AC INLET ASSY MAIN UNIT FAN ASSY MAIN UNIT FAN ASSY VACUUM PUMP ASSY VACUUM PUMP ASSY SOLENOID VALVE ASSY VOLUMET SOLENOID VALVE ASSY VOLUMET RINSING CUP ASSY SOLENOID ASSY SOLENOID ASSY X AXIS MOTOR ASSY X AXIS MOTOR ASSY REAGENT STAGE ASSY SAMPLE STAGE ASSY LIGHT SHIELD COVER ASSY PRINTER COVER ASSY REAGENT RACK ASSY REACTION TUBE TRASH BOX RINSE BOTTLE ASSY CA 5H 2L RINSE BOTTLE ASSY CA 5H 2L RINSE BOTTLE ASSY CA 500 WASTE BOTTLE ASSY CA 5H 2L WASTE BOTTLE ASSY CA 5H 2L WASTE BOTT
229. s ON 0 V when the mechanical stop switch is not ON Wiring Cord CN107 PCB No 6362 pin 9 and pin 10 5V 0 25 V when the mechanical for printer relaying stop switch is ON 0 V when the mechanical stop switch is not ON Figure 6 3 Mechanical Switch ON CA 500 Series S M 6 36 Revised December 2001 g 6 11 2 Turned Off During Operation Monitor Timing At the time when the power is turned ON Monitor Method CA 500 s Action Warning 1 Probable Cause 1 AC power supply failed 2 Fuse was burned 2 Confirmation by the operator 1 Check the AC power supply connection and fuse 3 Confirmation by Service Engineer 1 Check each unit carefully if the fuse is burned frequently 6 11 3 Light Shield Open Monitor Timing At time of analysis start during analysis and rising mode Monitor Method Photo interrupter monitors the light shield cover is open or closed by the light shield CA 500 s Action Emergency stop 1 Probable Cause 1 The light shield cover is opened intentionally 2 Foreign matters such as dirt and others on the sensor 3 Failure of the cover switch sensor 4 Failure of wiring cord wiring cord from CN19 on PCB No 4086 5 Failure of PCB No 6362 2 Confirmation by the operator 1 Remove the foreign objects on the sensor section 3 Confirmation by Service Engineer Suspect Part Test Points Expected Value ku ss Sensor Relay connector pin 2 and pin 1 Switch Sensor Relay connector _ Rela
230. sfers the reaction tubes b Mechanical Stop Switch otops the operation temporary 6 Detector Block Determines the coagulation time by measuring changes in the intensity of light scattered by increasing turbidity 7 Chromogenic Unit Detects the changes in the light absorbance by the transmitted light 8 Immunoassay Unit Detects the changes in the light absorbance by the transmitted light 9 Temperature Control Unit Controls temperatures for Detector Block Reagent Heater Section and Cooling Section 10 System Control Unit Controls Main Unit system 11 Drive Circuit Unit Controls each motor s driving 12 Pneumatic Unit 13 Sampler Unit Enables the continuous automatic operations by the sampler One sampler rack can contain 10 sample tubes CA 500 Series S M 1 2 Revised December 2001 g 1 3 5 Principles of Measurement 1 3 5 1 Biological Activation Method 1 2 Coagulation Reaction Detection Method Scattered Light Measuring Method Red light 660 nm is irradiated onto the mixture of plasma and reagent and the change of the scattered light is detected corresponding to the turbidity change when the fibrinogen is converted to fibrin Coagulation End Point Detection Method Percent Detection Method Let the scattered light intensity at the time when the coagulation reagent is added to be 0 and that when the coagulation reaction is completed to 100 The coagulation time is obtained from the time to re
231. t Mark Limits Replic Limits Report Limits Set Test Name Set Reagent Name Test Protocol Set Replication Test Group Reagents Holder Alarm Settings Conversion Host Computer Barcode Scanner Date Formt Password Standard Curve 2 Select the appropriate key Set To start user setting initializing When completing the Initial screen will return Cancel To cancel user setting initializing and return to the Initial screen 5 4 4 Initializing Entire Memory 1 Select Int Entire Memory key then the confirmation screen with Initialize Entire Memory message will appear When selecting this key the following items will be initialized in order User settings Items listed in 5 4 3 Stored data Error Log Total cycles Syringe cycles Group selection number Rinse Wait time Reagent volume Catcher test cycle counts Catcher test error times 2 Select the appropriate key Set To start entire memory initializing When completing the Initial screen will return Cancel To cancel entire memory initializing and return to the Initial screen NOTE By setting the DIP SW 202 Bit 6 on PCB No 6362 to ON position the BBRAM settings are cleared automatically at power ON CA 500 Series S M 5 6 Revised December 2001 g 5 4 5 Initializing Service Settings 1 Press Int Settings 2 key then the confirmation screen with Initialize Entire Memory message appear When selecting this key following service set
232. t Screen 11 4 3 4 Position Adjustment Procedure of Pipette 1 blood 1 2 blood 10 and 3 blood stat 13 4 3 5 Position Adjustment Procedure of Pipette 4 reag 1 5 reag 9 6 reag 10 16 4 3 6 Position Adjustment Procedure of Pipette 7 reag rinse 8 buffer 17 4 3 7 Position Adjustment Procedure of Pipette 10 wash 19 4 3 8 Position Adjustment Procedure of Pipette 11 p tube 1 21 4 3 9 Position Adjustment Procedure of Catcher 17 c tube 1 22 4 3 10 Position Adjustment Procedure of Catcher 23 warm 1 24 4 3 11 Position Adjustment Procedure of Catcher 27 shake 26 4 3 12 Position Adjustment Procedure of Catcher 28 dust 27 4 3 13 Position Adjustment Procedure of Catcher 29 28 ASA Output gei u ETT 29 TSM OC TAU SPS cesta pears m mm 30 4 4 1 Temperature Control Summary 30 442 Temperature Verification at Each Unit 4 30 443 Temperatu
233. t center of the screen If not change to 11 p tube 1 by using Pos and Pos keys 3 Move the pipette to the setting position by using XY TEST key 4 Use 7 J and gt keys to adjust the pipette tip to become the center of the reaction tube Ege mE Figure 4 3 16 Pipette Tip inside Reaction Tube CAUTION 1 Do not execute Z operation when XY adjustment is insufficient 2 Besure that the pipette tip is at the center of the reaction tube If not it may cause the pipette to touch the reaction tube when descended CA 500 Series S M 4 21 Revised December 2001 Press Z TEST key to descent the pipette The pipette detects 50 uL of distilled water and stops Use 1 lt and gt keys to adjust the pipette tip to become the center of the reaction tube Press Z ADJUST key again to ascend and descend the pipette Verify that the pipette is placed at the center of the sample cup The pipette detects the 50 uL of distilled water inside the reaction tube and stops Z pulses will be stored as the setting value in the memory when Mecha Position adjustment is completed Press XY ORG key to return the pipette head to the home position oetting Position 11 p tube 1 12 p tube 5 13 p tube 26 14 p tube 31 15 p tube 35 16 p tube 56 Adjust above 6 positions in the same way NOTE Referto 5 10 1 Position Adjustment for the default values Jump to Section 5 10 1 2 4 3 9 Positio
234. t current drive Power transmission Timing belt type Resolving power Approx 0 02 mm step Drive speed Approx 1300 pps at high speed in trapezoidal control sensor For drive unit home position transmission type 1 unit 2 Syringe System Piston diameter 3mm Vertical stroke Approx 21 mm syringe volume Approx 151 uL 21 mm Life 300 000 cycles 2 6 3 Assembly Diagram Pulley Idler CA 500 Series S M 2 7 Revised December 2001 8 27 X Y DRIVE UNIT X AXIS MOTOR ASSEMBLYIDRIVE AXIS ARM ASSEMBLY 2 7 1 Outline This unit moves the sample probe which aspirates and dispense plasma and reagent to the Sample Rack Reagent Rack and Reaction Tube Rack and drives in X Y direction the catcher which moves reaction tubes from the reaction tube rack to the heater section detector block and further to dispense discard hole 2 7 2 Specifications Functions 1 X Direction System Drive Source Unipolar type stepping motor 1 2 phase excitation constant current drive Drive transmission Timing belt type Resolving power Approx 0 08 mm step Drive speed Approx 4500 pps at high speed in trapezoidal control oensor For drive unit home position transmission type 1 unit 2 Y Direction System Drive Source Unipolar type stepping motor 1 2 phase excitation constant current drive Drive transmission Timing belt type Resolving power Approx 0 08 mm step Drive speed Approx 4000 pps at high speed in trapezoidal control
235. ta will be stored in the memory Continue Returns to the Service Setting screen and allows continuous operation CA 500 Series S M 5 2 Revised December 2001 8 Next Use this NN GN to i the following parameters Parameter Description Key to be Used whether to use Chromogenic Unit Next Option ON OFF whether to use Immuno Unit 1 Next Option ON OFF Dx Select the wavelength of the aperture for Next Optioin 5 5 nm or 800nm a Unit DFbg Next Option ON OFF APTT Warm w 120 thru 300 D Dimer Init Select the parameter for D Dimer Next Option DD PLUS Adv DD or LPIA DD Pg J J ON OFF Rinse menu when executing Maintenance Rinse executing Maintenance Rinse 1 2 and 3 indicated in the Desctiption of the table above correspond to 1 2 and 3 indicated at the beginning of this section For parameters which are set to OFF for 1 are as below e No test protocols will be displayed in the test setting screen e reagents will be displayed in the reagent name setting screen e The settings will not be initialized by using Init Settings 1 and Init Entire Memory on the Initial menu CA 500 Series S M 5 3 Revised July 2003 5 3 ADJUST Use to adjust the hardware positions sensitivities etc Refer to Section 4 Adjustment for the adjustment procedures of each item From the Main menu press Special Operate Service Adjust keys
236. tandard curve is not satisfied on actual analysis 2 Confirmation by the operator 1 Preset more than two points 3 Confirmation by Service Engineer The same as above 2 CA 500 Series S M 6 34 Revised December 2001 g 6 10 4 Standard Curve Error Monitor Timing When preset the Standard Curve Monitor Method Monitors the preset limit and actual data CA 500 s Action Warning 1 Probable Cause 1 Data of Standard Curve is out of limit 2 Confirmation by the operator 1 Preset the correct data of Standard Curve 3 Confirmation by Service Engineer The same as above 2 CA 500 Series S M 6 35 Revised December 2001 8 6 11 OPERATION ERRORS 6 11 1 Interrupt by Mechanical Stop Monitor Timing During operation Monitor Method Monitors Mechanical Stop Switch ON or OFF CA 500 s Action Emergency stop 1 Probable Cause mechanical stop switch has been pressed Failure of the mechanical stop switch Failure of PCB No 9265 Failure of wiring cord for printer relaying Failure of PCB No 6362 2 Confirmation by the operator 1 Confirm whether the mechanical stop switch is pressed or not 3 Confirmation by Service Engineer Suspect Part Test Points Expected Value Mechanical Stop Switch CN3 PCB No 9265 pin 1 and pin 2 5 V 0 25 V when the mechanical stop switch is not ON PCB No 9265 CN1 PCB No 9265 pin 3 and pin 4 5 V 0 25 V when the mechanical stop switch i
237. tcher for 70 pulses 5 Use lt and gt keys to move the pipette position to touch the interior surface of the reaction tube When the pipette tip touches to the copper tape inside the tube the liquid sensor display on the screen changes from the white circle to the black circle This X pulse is the setting value 6 Press Pipette Return key to descend the catcher for 70 pulses Z pulse will be back to 40 Q Pipette 70Pulses below Z Puise Setting Value Figure 4 3 24 Catcher Adjustment 7 Press XY key to return the pipette to the home position CAUTION DO NOT press Z ORG Z TEST or Z ADJUST key That will cause pipette crash CA 500 Series S M 4 26 Revised December 2001 4 3 12 Position Adjustment Procedure of Catcher 28 dust Adjustment Parameter Catcher Position XYZ pulses of Reaction Tube Trash Summary Adjust the catcher XY and Z positions of the reaction tube trash by setting the reaction tube to the catcher Standard Position Y direction A center of the waste position mark on the panel agrees a center of the reaction tube Z direction Z pulse position is at 13 pulses approx 1 mm above the panel X direction When 2 pulse is as above the reaction tube caught by the catcher 1 at the panel side of the reaction tube trash Almost touches the trash 1 XY Adjustment Place the reaction tube to the catcher Verify that the 24 is shown on the
238. ter of the catcher Figure 4 3 26 Y Direction Adjustment b X direction Use lt and gt keys to adjust the horizontal position of catcher The catcher once ascends and then descends by pressing Z ADJUST key Adjust the reaction tube position in X direction to touch the left part of the inner wall of the immunoassay well by repeating this operation Catcher Reaction Tube Immunoassy Well Figure 4 3 27 X Direction Adjustment CA 500 Series S M 4 28 Revised December 2001 Zdirection Use Catcher DOWN key to confirm the position where reaction tube hit the bottom of the immunoassay well Touch around the immunoassay well to confirm the vibration of the hit or touch the reaction tube to verify that there is no more play Press Catcher UP key for 2 times The Z position can be also adjusted by using Tube Catch key and Tube Free key and aligning the upper edge of the reaction tube brim with the lower surface of the upper catcher part Upper Edge of the Reaction Tube Brim Lower Surface of the Upper Catcher Part Figure 4 3 19 Z Direction Adjustment 7 Press Tube Free and Tube Catch keys to verify that the reaction tube to be caught and released smoothly 8 When the adjustment is completed catch the reaction tube and return the catcher to the Z home position by using Z ORG key Move X axis 5 pulses towards to the left by pressing lt key for 5
239. the power switch is OFF at O 2 Connect the connection cord to HOST on the right side panel and tighten the screw to fix it HOST connector Figure B 8 Connecting to HOST Computer CAUTION Confirm the power switch is OFF at before routing the connection cord otherwise there is a hazard of electrical shock For setting host computer interface parameters refer to Operator s Manual Chapter 10 Section 5 1 Host Computer he connection cord for the host computer is not included in the accessories CA 500 Series S M B 7 Revised December 2001 g B 7 Set Print Paper 1 Remove the printer cover It can be removed by raising the lower edge of the printer cover Printer Cover Figure B 9 Removing the Printer Cover 2 Release the lock Raise the lock lever to unlock Figure B 10 Releasing the Lock 3 Load a paper roll Load a new print paper roll Print Paper Figure B 11 Loading the Paper Roll CA 500 Series S M B 8 Revised December 2001 4 Pass print paper Pass the print paper as shown below and throw down the lock lever to lock Lock Lever Figure B 12 Passing the Print Paper 5 Feed print paper If power is turned ON press Sysmex key then P FEED on the Sysmex Menu screen Ready HC IP Replace Rack YES Figure B 13 Sysmex Menu Screen 6 A Attach the printer cover CA 500 Series S M B 9 Revised December 2001
240. times This is the X adjustment value 9 When completed press XY ORG key to return the catcher to the home position 4 3 14 Output Setting Values 1 Press Return or Quit key on the right bottom of the screen to display the confirmation screen as follows Sysme Ready IP Replace Rack YES Mecha Position RENEW SETTING Cancel Continue Figure 4 3 27 Confirmation Screen 2 Press FIX key to update the setting value and then output CA 500 Series S M 4 29 Revised December 2001 4 4 TEMPERATURE ADJUSTMENT 4 4 1 Temperature Control Summary The temperature control CPU gets each unit s temperature by A D converted signal as a temperature from the Sensor Due to the voltage comes out from the temperature sensor is various the Main CPU sends the Offset value to the temperature control CPU for each sensor to get the temperature within the range 4 4 2 Temperature Verification at Each Unit The unit temperatures displayed on the Temp Control screen are the temperatures at each thermister For the temperature adjustment the actual temperature at each unit must be checked as follows 4 4 2 1 Cooling section Reagent Cooler After 30 minutes since turning power ON of CA 500 perform the following procedures 1 Pour4 mL of distilled water into DADE 1 mL bottle and put it into position No 4 of reagent rack 2 Measure temperature of the water and confirm that temperature is within 15 0 2 C 4422
241. ting items will be initialized in order Service Settings Analysis Parameters Confirmation Mode Reagent Vial Settings Gain Correction Coefficient 2 Select the appropriate key Set To start service setting initializing When completing the Initial screen will return Cancel To cancel service setting initializing and return to the Initial screen 5 4 6 Data Check 1 Select Verify Control key then the confirmation screen with Initialize Entire Memory message will appear 2 Select the appropriate key Set To perform memory check in order of following screen The check result will be indicated OK The number on the screen 8333 indicates the checksum value of Flash Memory Cancel To cancel memory check and return to the Initial screen 3 When Set is pressed memory check will be performed in the following order Flash Memory Motor position adjustment value Detector Block adjustment Temperature control Pressure adjustment Manufacturer settings Service settings Analysis Parameters Reagent Bottle Customer settings Standard Curve Each sample data in stored data Each file data in QC data Important Note that any NG file is automatically initialized E Ready IP 5 Initialize Verification Control Table in progress 8333 Position OK Maker Set OK User Set OK Standard Data OK Stored Data OK Quality Control OK Return
242. tion tube 2 When Probe Crash appears even no crash has occurred or for an unstable situation confirm the following a Slide the probe up and down in the probe holder If this improves the situation the probe holder assembly might have a trouble Suspect Part Test Points Expected Value Probe Crash Sensor CN5 PCB No 2134 pin 1 GND and pin2 5V gt 0 V when probe crash occurs CN1 PCB No 2134 pin 16 GND and pin 7 5 V 0 V when probe crash occurs CN1 PCB No 9260 pin 16 GND and pin 7 5 V 0 V when probe crash occurs 105 PCB No 6362 pin 13 GND and pin 5 V 0 V when probe crash occurs 4 PCB No 2134 latches Crash signal each time So confirm the above by pressing the liquid level sensor reset switch in the service mode CA 500 Series S M 6 18 Revised December 2001 g 6 5 6 Syringe Error Monitor Timing When sensing home position during operation Monitor Method Photo interrupter is shaded by the light shield to drive mechanism CA 500 s Action Emergency stop 1 Probable Cause 1 The motion of drive mechanism is obstructed Loosened pulley of motor Failure of home position detection sensor Defective light shield Flaws on shaft Failure of bushing Failure of PCB No 9265 Failure of wiring cord wiring cord from CN19 on PCB No 4086 Failure of PCB No 6362 10 Failure of syringe motor 11 Failure of wiring cord printer relay flat cable 12 Failure of PCB No 4086 Ceo E
243. tive voltage of the LCD drive is created from 5 V by the DC DC Converter U704 For the contrast signal the voltage divided from the above negative voltage by the external volume PCB No 9263 VR is supplied to LCD CA 500 Series S M 3 18 Revised December 2001 10 Serial Interface 0201 601 602 The RS232C Serial communication is performed with the external Host Computer with using one of three channels of the serial interface for asynchronous communication built in CPU U201 Buffers U601 602 having the DC DC Converter within it are used as the level converter 11 Touch Screen Interface U201 U703 4 5 6 8 9 10 With using one of three channels of serial interface built in the CPU U201 for asynchronous communication interface with the LCD touch screen by TTL level serial communication is performed 12 ID Unit Interface U201 603 With using one of three channels of serial interface built in the CPU U201 for asynchronous communication the serial communication with the ID Unit Interface is performed Output signal for the ID reading timing and the ID reading OK NG input signal are interfaced at the CPU port The buffer U603 having the DC DC converter within it is used as a level converter 13 MEMORY CARD Interface CN102 The CPU U201 uses the specified MEMORY CARD storing the program in the 68 pin card slot CN102 This 68 pin card slot is directly connected to the internal bus Inserting the other card than sp
244. ustments are not necessary 3 4 3 LED and Test Point There are no LEDs or test point 3 5 PCB No 2134 Y Z RELAY Liquid Surface Sensor Probe Crash Y Axis Home Position Sensor Z Axis Relay PCB No 2157 Y Z RELAY2 Liquid Surface Sensor Probe Crash Y Axis Home Position Sensor Z Axis Relay 3 5 1 Function This is the detection circuit of the liquid surface sensor which uses the capacitance change method in which liquid surface is detected by capacitance change when the probe touches the liquid surface This circuit also has the Probe Crash Detection Y Axis Home Position Sensor and relay to the Z Axis signal 1 Liquid Surface Detection Circuit Liquid surface of sample reagent buffer or rinse water is detected and a detection signal is issued Detection signal is also issued when the probe is removed from the liquid surface 2 Probe Crash Detection Circuit Probe crash is detected and a probe crash signal is issued 3 Probe Arm Y Axis Home Position Sensor 4 Probe Arm Y Axis Motor Signal Line Relay 5 Relay to PCB No 9264 2 RELAY 3 5 2 Block Diagram SE Guard Shielding Oscillator IN Detecti Hi MA 4 ighpass Limitter Amplifier 1 Buffer Circuit Filter D tm DM m Amplifier 2 mparator _ Flip Flop Liquid Surface Detector Signal to PCB No 6362 MAIN 1 T3 Reset Sig
245. uu 5 2 5 AUST T 5 4 5 3 1 Printing Adjustment Data 5 4 57 nee 5 5 5 4 1 Initializing Stored 5 5 5 4 2 Q 5 6 5 4 3 ZUG User Soli uuu ERE o EM 5 6 5 4 4 E ure AVIGNON Y LLULLU LIL EO Em 5 6 5 4 5 Initializing Service Settings 5 7 5 4 6 BAS Wem 5 7 5 4 7 Contents stored in 5 7 5 4 8 Contents stored in EEPROM 5 8 5 4 9 Items needing backup when initializing 5 8 55 n0 5 9 5 5 1 E E E 5 9 5 5 2 Dispense 5 10 5 5 3 FUER OWO u u E et ce ett cen E anc E E E 5 11 5 5 4 Reagent Temp 5 12 5 5 5 Tube Transfer Test 5 12 5 5 6 a cleric cet 5 13 20 5 14 O 5 17 5 7 1 Analysis Check 5 17 5 7 2 RINSE Wait 5 17 5 7 3 ES A COO
246. ver 3 Pull out the connector from the duct and disconnect the connector CA 500 Series S M B 14 Revised December 2001 4 Remove sampler Release the stoppers while pushing the stopper levers by fingers and remove the sampler Figure B 23 Removing the Sampler 3 Attach the slide rail to the sampler with the ID bar code scanner 1 Remove the slide rail from the removed sampler Loosen the screws as shown and remove the slide rail from the sampler Take care not to lose the slide rail screws or washers that were removed as they must be attached to the sampler with the ID bar code scanner Screws Screws Figure B 24 Removing the Slide Rail 2 Attach the slide rail to the sampler with the ID bar code scanner Mount the duct attached slide rail to the sampler onto the side where the cable protrudes All four screws should be temporarily tightened 3 Insert the cable from the sampler into the slide rail duct CA 500 Series S M B 15 Revised December 2001 8 CA 500 Series S M Install the sampler with the ID bar code scanner to the CA 500 main unit 1 While finger pushing the stopper lever to release the stopper push in the sampler a few centimeters on the inner rails of the CA 500 main unit Inner Rail Figure B 25 Inserting the Sampler CAUTION Until you are sure the sampler with ID bar code scanner will not disconnect do not let go hands 2 Push the sampler with ID bar code scanner in paral
247. wer ON the instrument Use the scattering stick after being heated for more than 10 minutes in the detector well or the incubation well Close the light shield cover to avoid the influence by the external light during adjustment When Detector Adjustment Error occurs the channel No with the error is added to the error message Note 1 Transmitted Light calibration will be performed automatically before the first measurement after switching on the instrument or after 24 hour continuous operation It will be performed when a chromogenic or immunologic parameter is selectable in the actual group setting 2 Instruments with new main board PCB NO 6373 are able to switch off LEDs during standby operation automatically in order to prolong the life time of the LEDs CA 500 Series S M 4 5 Revised May 2003 ECR 303 012 4 2 3 1 Adjustment of Detector Well for analyzing the scattered light Offset adjustment 1 Insert the ebonite stick for adjusting the offset value in the detector well to be adjusted small Serpia Incubation Well 3 2 Well 1 Q Detecti uw v Reaction Tube Trash CH 1 Detection Wel Detection Wall Im Chromo genie CH6 CHS Datectio Detection Wail 4 Wal 3 CH 4 CH 3 Weil 6 Wali 5 Wall 4 a Probe Rinse CupiOuteide Probe Cup Inaide Figure 4 2 3 Detector Well Positions Close the light shie
248. y connector pin 2 and pin3 PCB No 9265 CN112 PCB No 6362 pin 8 and pin 9 when shield cover is CLOSED 5 V 0 25 V when light shield cover is OPEN Wiring Cord CN112 PCB No 6362 pin 8 and pin 9 Does not change the signal when light wiring cord from CN19 shield is OPEN or CLOSED or PCB No 4086 CA 500 Series S M 6 37 Revised December 2001 g 6 11 4 Enter Work List Monitor Timing At time of analysis start Monitor Method ooftware CA 500 s Action No analysis 1 Probable Cause 1 The Work List is not registered 2 Operation error 2 Confirmation by the operator 1 Register the Work List correctly 3 Confirmation by Service Engineer The same as above 2 6 11 5 Check Reagent Volume 1 Monitor Timing At time of analysis start Monitor Method Monitors preset data on EEPROM and actual accumulated amount of volume CA 500 s Action Warning 1 Probable Cause 1 When reagent volume monitor in valid the theoretical calculation volume of reagent exceeds the used reagent volume 2 Confirmation by the operator 1 Replenish reagent and input new data of reagent volume 3 Confirmation by Service Engineer The same as above 2 6 11 6 Insufficient Reaction Tube Monitor Timing At time of analysis start Monitor Method ooftware CA 500 s Action Does not analyze 1 Probable Cause 1 The number of test registered in Work List exceeds that of the remaining reaction tubes a maximum o
249. y using 2 ORG key Move X axis 5 pulses towards to the left by pressing lt key for 5 times This is the X adjustment value 9 When completed press XY ORG key to return the catcher to the home position 10 Setting Position 18 c tube 5 19 c tube 26 20 c tube 31 21 c tube 35 22 c tube 56 Adjust above 5 positions in the same way CA 500 Series S M 4 23 Revised December 2001 4 3 10 Position Adjustment Procedure of Catcher 23 warm 1 Adjustment Parameter Catcher Position XYZ pulses of Detector Block Summary Adjust the catcher XY and Z positions of the detector block by setting the reaction tube to the catcher Standard Position X direction 5 pulses to the left of the line where the left surface of the reaction tube when descended agrees the interior surface of the sample incubation well Y direction The center of the catcher agrees the center of the reaction tube when the reaction tube is descended Z direction 5 pulses above the line where the bottom of the reaction tube agrees to the bottom of the incubation well The lower edge of the reaction tube brim should be aligned with the upper surface of the lower catcher part 1 XYZ Adjustment 1 Place the reaction tube to the catcher 2 Verify that the 23 warm 1 is shown on the left center of the screen If not change to 23 warm 1 by using Pos and Pos keys 3 Move the catcher to the setting position by using XY TEST key 4 Use

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