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http://utomir.lib.u-toyama.ac.jp/dspace/ Title 富山県内一般若年者の
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1. ie 1 1 6 10 1 2 6 660 4 400 ti
2. FIWE RE 7 A 4 6 66 5 84 5
3. 2 1998 CDC 5 1999 4
4. 2002 641 149 24 0 20 7 0 5 12 LRE s NTO 1263 IgE 0 5 4 A Bh
5. SPSSver 11 Fisher p lt 0 01 2 1 Hevea 67osz7zezs7s JMS PBS 12 180 g ml 2 10 20 READYGELS J BIORAD161 539J BIO RAD
6. 75 0 D 36 3 25 0 18 8 3 8 7 8
7. DEW tC HAIKU SHRI ORES VES Rig POS 78 89 21 3 17 5 16 3 LIDS 4 DA RAR mO Mio ya yem
8. 2002 6 10 _3 YD HIE 5 2 2004 1 1 2 DEAZ 3
9. RESAH JMS Ancell Medical C 13672448 X RA 1 90 1537 1542 2002 2 E GR AORN 1999 3 FEAH F Bu fi 4 33 35 2000 4
10. FOR 2001 405 80 19 8 COME 20 79 1gR 70 0 11 3 5 2 2004
11. F BOSD 200 Hev bl Hev b11 11 CHS IgE 100UA ml
12. 4 OF l DET SS 5 4 ite lt Le 6
13. 373 92 1 4 _ 1 28 7 3734 92 1 28 6 9 4 0 9 2 2 80 19 8 325 80 2 4 6 3 66 3 8 8 3
14. Liss 5 2 15 50 40 9 8 8 2 6 IgE
15. BIO RAD 2000 13 60 46 51 2002 14 60 643 651 2002 15 60 ttt 652 656 2002 16 60 659 664 2002 17 5 1020 1028 1998 18 MEE 22 427 431 2002 19 1999 20 Baur X Chen Z Allemers H Raul Heinsoth M Results of wearing test with two different latex gloves with and without the use of skin protection cream Allergy 53 441 444 1998 21 BAA T 21 661 664 2002 22 Liss GM Sussman GL Deal K Brown S Cividino M Beezhold DH Smith G Swanson MC Yunginger J Douglas A Holness DL Lebert P Wasserman 5 TurjanmaaK Latexallergy epidemiological study of 1351 ho
16. 1 IgE 2 IgE BIO RAD161 0301 1 IgE 100UA ml 3 3 Sigma C Sigma 20 g ml PBS 37C 1 Lares mo R 1 405 38 2 191 47 2 214 52 8 12 6 2 7 CHE 1 15 1
17. IgE He vBl HevB7 37C 1 OAK Hevea brasiliensis 65 30 2 2 1 4 Al 2
18. 0 5 22 59 34 5 3 4 3 1 8 60 3 Mal 70 0 11 3 11 3 2 SF yD ABER i N 80 N 325 N 405 9 0 3 4 13 5214 12 62 22 7 36 45 0 155 47 7 191 47 2 44 55 0 170 52 3 214 52 8 lia FS A 53 66 3 112 34 5 165 40 7 B 7 8 8 11 3 4 18 4 4 A B 60 75 1 123 37 9 183 45 1 C 2 0 5 6 1 8 8 2 0 rat A B C 62 77
19. TERE 1 45 1 0 4 4 5 19 9 5 9 7 8 10 50 20 0 SEIS TER 16 2 6 32 5 20 FE 5 15 SDS 2 39 4 4
20. 58K 46K Hev b1 Hev b7 IgE 31KK 11 2 Hev bl Hev b7 Hev bl Hev b7 BA ant
21. 12 6 2 7 1 157 T 191 214 45 1 80 19 8 4 6 70 0 1 1 3 11 3 78 8 22 0 16 0 4 1 36 6 25 0 7 8 IgE
22. 7 IgE 58K 46K 31 3 31 58K YRO4F Vb YORBADBT VV T VBE T Y 8 58K 46K IgE 58 Kda 46 Kda mmm wi 31 Kda gt lt Neuer oe 7 P IgE P lgE
23. CDC Infection Control 1999 5 E 4 115 125 2002 6 BAB PRAISE ETE REE 616 618 2002 7 Franland AW latex allergic children Periatric allergy Immunol 10 152 159 1999 8 Liss GM Sussman GL Latex sensitqaization occupational verus general population prevalence rates Am J Indust Med 35 96 200 1999 9 Hourihane JO Allard JM Wade AM McEwan AL Srobel S Impact of repeated surgical procedures on the incidence and prevalence of latex allergy a prospective study of 1263 children J Pediatrics 140 467 482 2002 5 2 2004 10 KASS NH 4 _ 25 32 2000 11 42 48 1997 12 BIO RAD
24. yO K lt gt A ERDERA gt 6 2 Eo Sank Oe ee eari Siei te 58 Kda mp 46 Kda gt 31 kda 8 5 R 38 2 1 3 405 TS
25. ToRepo Suk pe RS PU UNG RIO of dna Repository P g 1 Kiki di Tar ig ae PERUON AS uu Title Author s M er Se Se ae CH BS BSE UBER AE Le Reme WW http utomir lib u toyama ac jp dspace 5 2 2004 EMRE BAR 1 2 3 4 5 E 405
26. 17 21 3 5 2 2004 20 25 0 20 25 0 15 18 8 3 3 8 M4 31 38 8 23 28 8 Bol 5 6 3 5 6 3 16 20 0 5 16 ee 20 0 234 28 8 5 6 3 31 38 8 5 6 3 N 80 5 ULG OLLGGQ QQ 83 78 8 0 10 20 40 50 60 70 3 3 3 8 15 18 8 0
27. 20 25 0 WLLL 20 25 0 RAR Di LLL LL LL LL LL LL LL LL LL LL LALLA 29 36 3 0 5 10 20 25 30 35 A 4 4 20 12 4 H REB 3 22 2 EK 17 85 0 3 15 0 6 17 85 ne 0 10 20 30 40 50 60 70 6 5
28. 1 OKH OAH 7 Oa tz fay _ 8 OBL iis Oe Ofte 9 COR Diz o OA 10 3
29. 596 129 39 7 191 47 2 18 22 5 196 60 3 214 52 8 OK 3 p lt 00 1 7 5 2 9 11 3 6 7 5 9 11 3 Bl 96 N 80 2 3 80 KE 63 78 8 17 21 3 14 17 5 13 16 3 7 8 8 4 4 4 3 29 36 3 2 4 4 4 7 8 8 SIEI 13 16 3 14 17 5
30. not known the latex allergy suggesting that educational activities should be provided to inform them the increasing prevalence rate in children potential risks and manifestations including lethal anaphylaxis Western blotting analysis using a latex IgK positive serum showed that two bands corresponding to Hev Bl and Hev B7 well known allergens in latex proteins could be detected before the treatment of latex proteins with trypsin or papain 37 C lh but not after the treatment This finding strongly suggest that enzyme treatment of latex might be useful to prepare low allergic latex products Key words latex allergy children latex sensitization low allergic latex proteolytic enzyme
31. HIAI 1 Department of Adult Nursing Acute Stage Toyama Medical and Pharmaceutical University 2 Division of Nursing Nagoya University Hospital 3 Department of Oriental Medicine Toyama Medical and Pharmaceutical University 4 Department of Human Science Toyama Medical and Pharmaceutical University 5 Department of Public Health Toyama Medical and Pharmaceutical University Abstract We carried out an epidemiological study on the latex sensitized children through the analyses of answers on the questionnaire obtained from 405 children with the mean age of 12 6 years in Toyama Prefecture As much as 191 responders 49 1 showed either symptom of the immediate type allergy Especially 80 responders 19 8 were classified into latex sensitized group LSG because their symptoms were induced by latex related products such as sticking plaster and rubber gloves and balloons LSG was 4 6 years younger and showed a significantly higher prevalence rate of allergic diseases than the remaining 325 children Although most of them suffered from cheilo dermato rhino ocular and or asthma like symptoms with the duration time of 1 to several days 4 children answered anaphylaxis like symptoms low blood pressure and unconsciousness To control these symptoms they avoided the use of causative latex related products or consulted with doctors but no children received diagnostic tests of latex allergy Most children and their parents 92 1 have
32. spital workers Occupat Envirm Med 54 335 342 1997 23 Latex fruits syndrome 8 894 899 2001 24 48 1 4 1999 25 Banerjee B Kanitpong K Fink JN Zussman M Sussman GL KellyKJ KurupVP Unique and shared IgE epitopes of Hev Bl and Hev B3 in latex allergy Mol Immunol 37 789 798 2000 26 1 63 68 1997 27 Perella FW Gaspari AA Natural rubber latex protein reduction with an emphasis on enzyme treatment Methods 27 77 86 2002 28 Chardin H Mayer C Desvaux FX Senechal H PeltreG Latex allergy characterization of major allergens and isotypic expression Allergy 54 872 877 1999 5 2 2004 Epidemiological study on the latex sensitized children in Toyama Prefecture and an attempt to develop a low allergic latex protein by proteolytic enzyme treatment Miki YATSUZUKA Satoko KONOSU Nobuko IMANISHI Miyuki SATO Yuko KATADA Kyoka UEDA Hidetoyo TERANISHI and Hiroshi OC
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