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1. ke2. 56 40 4 i 57 pH 2 60 43 5 ppm 2 V79 30 25 20 10 6 27 50 i 58 pH 2 60 50 ppm x x 28 JCRB0608 V79
3. 12 90 34 28 28 43 44
4. 15 20 21 22 1993 pH 2 47 48 ppm ICR 7 27 6 81 8 g 28 1 25 5 g 5 14 5 3 14 mkg 24 36 54
5. 13 pH 2 7 25 mg kg 250 ml 8 4 14 pH 2 7 32 mg kg 1 100 ml 3 4 15 pH 2 7 30 mg kg 100 ml 3 4 2 7 p
6. 90 pH 1 CTI Cl gt
7. 26 plate 8 9 ul Mix TA102 TA1585 TA1537 ee 80 844 19 25 21 40 5 113 270 15 24 23 41 10 126 810 20 33 26 36 50 103 250 18 80 24 28 100 115 348 18 28 24 43 500 105 242 16 24 19 80 1000 87 70 12 20 10 21 0 116 277 20 29 30 87 1 111 406 18 28 24 40 5 103 426 20 26 35 31 10 108 392 19 27 37 34 50 132 330 21 30 38 30 100 108 376 19 26 25 43 500 123 262 15 23 27 27 1000 92 272 9 22 13 28 0 01 78 AF 2 0 1 174 2 0 378 NaNs 0 5 288 ICR 191 1 680 EE MMOC 1 1768 g plate AF 2 2 2 fury1 3 nitro 2 fury1 acrylamide NaNs sodium azide ICR 191 2 methoxy 6 chloro 9 3 2 chloroethy aminopropylamino acridine 2HC1 MMC mitomycin C 2AA 2 Aminoanthracene 27 v
8. 7 2002 NO 7 11 3 14 1 0 25 0 5 1 0 1 Vol 36 4 1998 4 15 1 100 ml Vol 38 1 2000 5 16
9. 30 mLday 15 mday 32 RBC WBC Hb Ht MCV MCH MCHC 13 13 13 13 RBC 833 7 843 5 727 5 x 10000 mm3 BI ptt Be Tal ne 00 WBC Un 11300 10800 6417 8000 7533 10050 3100 8982 1658 210 3231 6288 Hb g d 15 43 15 39 15 6 14 48 15 28 0 5 0 5 0 7 0 9 1 7 Ht 46 15 46 36 42 17 43 18 48 2 2 4 2 1 0 3 5 4 2 MCV 1 m3 54 83 57 83 56 83 58 7 2 6 55 3 1 8 60 7 2 8 2 1 MCH pg 18 17 19 83 a 19 8 2 1 18 5 0 8 Ra 21 8 1 1 La 20 6 0 4 MCHC 33 33 34 33 a 33 7 0 8 33 8 0 8 i 34 3 0 8 0 35 5 0 5 8 D
10. 84 3 8 3 pH 2 7 40 mg kg 200 1 10 a 1 200 10 a 3 1 pH 2 7 40 mg kg 200 10 a pH 2 7 40 mg kg M 30X60 cm9 30
11. 14 mkg 11 16 24 36 54 54 mkg 9 4 ml kg 9 mkg 2 54 ml kg 4
12. 1000 plate 2 500 250 125 62 5 pplate 5 62 5 1000 plate 18 KC hydrochloric acid buffer pH 2 0 g plate plate S 9 uy Mix plate TA100 TA1535 1000 114 13 KCI HCl 500 115 11 62 5 126 11 125 125 13 250 121 16 500 137 12 1000 84 4 9 1000 122 15 KC HC 500 127 14 62 5 123 12 125 134 12 250 124 16 500 125 15 1000 FE 134 17 0 0
13. 82 2 0 01mg l 83 8 0 059mg l 0 01mg 1 25C 84 0 046mM 3 84mg l lt 0 0012mM 0 10mgm 85 KD LD50 1870mg kg 86 60 70 5 30
14. 1 1000 plate 24 AF 2 01 Ss 146 20 318 NaNs 0 5 1544 1CR 191 1 265 0 5 52 1 186 2 23 35 20 40 2AA 0 5 863 1 780 2 463 166 20 1288 pglplate ul plate 0 S 9 Mix mA100 TA1535 WP2 TA98 TA1537 uvrA 163 16 57 81 21 168 18 55 93 12 plate AF 2 2 2 fury 3 nitro 2 fury acrylamide NaNs sodium azide ICR 191 2 methoxy 6 chloro 9 3 2 chloroethy aminopropylamino acridine 2HC1 2AA 2 Aminoanthracene 25 iy
15. 50 HC1O 52 5 HC 36 5 Cl 71 HzO 18 KC1 74 5 0 2 pH 6 5 10 60 mg kg 0 2 pH6 5 10 60mg kg 0 2 1 99
16. pH pH 200 ml 300 ml 500 ml 8 6 pH 6 08 pH 5 86 pH 5 60 a oy pH 6 12 pH 6 18 pH 6 23 a pH 5 26 pH 5 24 pH 5 16 pH 6 52 pH 6 50 pH 6 47 38 JOIS JST
17. 10 2 2003 p 107 113 12 11 p 64 67 7 2002 p 44 47 5 7 2002 p 54 57 Vo1 31 1 2005 p 15 19 Spray Application of Electrolyzed Water on Leeks for Reduction of Viable Bacteria and Growth Promotion 1997 p 33 34 Ne No 2 2002
18. 30 6 hr 24 0 6 100 48 1 9 20 5 40 24 0 4 80 0 3 20 40 48 J 5 80 1 3 11 24 40 MMS 11 48 0 34 89 Mx 0 2 100 0 22 5 1 10 45 0 3 90 1 2 22 5 0 2 45 1 90 2 3 10 D 1 CP 10 1 9 gplate MMS Methyl Methanesulfonate CP cyclophosphamide 31 90 90 31 31 2 2 1996 84
19. 1993 pH 2 2 2 5 30 50 mg kg 4 Crj CD SD 1 10 5 28 3 10 1 10 1 10 2 10 1 10 1 10 4 10
20. 3 4 i 61 pH 2 56 2 68 40 02 47 22 ppm 8 12 13 2 5X2 5 cm 0 5 ml 1 3 1 15 30 5 62
21. 1921 10 pH 9 14 EPA 1998 1999 Amano Corporation Koken Ltd HOSHIZAKI AMERICA INC 3 Pesticidal Device 1999 FDA
22. GOT GPT LDH ALP gt GTP LDH ALP GOT UI 37 30 5 10 4 22 1 3 8 23 1 5 0 25 4 12 3 GPT UI 87 55 3 22 4 30 2 2 8 65 7 29 4 84 2 82 8 LDH UA 87 422 3 85 3 441 9 121 7 829 8 118 0 175 7 71 8 ALP IU 87 275 8 29 7 429 8 112 6 221 8 21 5 199 7 51 2 0 1 5 2 3 0 2 0 4 0 2 0 4 7 g dl 4 9 0 4 4 9 0 1 5 7 0 3 6 1 0 3 33 BUN 23 2 1 6 22 8 1 5 25 2 2 9 23 7 2 1 0 98 0 10 0 78 0 04 0 77 0 10 0 82 0 03
23. 30 ml kg 100 g 3 ml 18 1 15 15 _ ml kg 30 mUke mVke 2 30 mkg 14 ii
24. 2 1 3 15 4 15 4 24 15 5 7 40cm 1 2 m 200 V10 a 1 3 86 0 8 pH 2 7 40 mg kg 2 3 15 4 30 cm 1 2 m 200 10 a 1 1 4 100
25. pH 2 57 40 ppm 6 2 0X2 0 cm 0 2 ml 4 5 63 pH 2 45 50 ppm 2 0X2 0 cm 1 5 ml 4 5 42 iv 64 pH 2 48 2 48 45 50 ppm 2 5 k
26. 66 pH 2 60 50 ppm a FDI 0 859 NaCl 5 ml 0 2 ml 60 5 0 D 0 D ee xX 100 Os 0 D 0 D 43 5 38 1 60 51 0 b Parpart 11 NaC1 0 85 0 75 0 65 0 60 0 55 0 50 0 45 0 40 0 80 0 20 0 10 0 1 ml MCF
27. 7 1 ml 30 10 10 5 2 i 75 pH2 47 48 ppm 46 6 SPF 20 20 30 3
28. 81 150 6 3 2 87 pH2 7 40mg L 10a 800L 30cm lt 0 05ppm 34 44m3 3 0 12 0 18ppm
29. 1532 16 7500 48 10 60mg kg pH 6 5 1000 3000 88 pH
30. 28 1990 pH 2 52 35 ppm Salmonella typhimurium TA100 TA102 TA1535 TA98 TA1537 Bscherichia coli WP2 uvrA S 9 Mix Ames 1 1000 1plate 7 500 1000 plate TA98 TA102 1000 plate 500 plate 1 1000 plate
31. 500z1 plate 200 plate 2 1 200 gplate 22 plate S 9 ul Mix lat plate TA100 TA1535 WP2 TA98 TA1537 uvr A 0 164 20 33 48 26 1 205 15 30 60 17 5 188 23 21 56 27 10 194 17 33 40 22 50 166 21 28 38 22 100 161 19 24 22 22 200 93 14 24 10 21 0 190 28 27 54 53 1 203 13 27 48 58 5 200 20 27 45 65 10 206 18 28 56 67 50 191 21 24 43 62 100 152 14 36 33 65 200 97 17 20 19 56 0 01
32. 45 ry 72 pH2 53 40 ppm 938 3 2 4 7 Draize 2 i 73 pH 2 47 48 ppm 10 1 ml 10 20 80 20 80 i 74 pH 2 45 45 ppm
33. 38 80 100 gt gt to 0 1 2 3 4 5 6 7 8 9 10 PH 39 3 1 53 pH 2 28 lt 2 50 50 ppm Hartley 26 0 05 ml 1 0 1m 2 0X4 0 cm 48 2 0 1 ml 2 0X2 0 cm 24
34. 0 1 ml 30 1 24 48 72 Draize 0 ii 70 pH2 57 40 ppm 9 2 4 8 7 Draize 71 pH 2 45 50 mg kg 3 3 2 4 7 Draize
35. 18 8 1 08 5791 8031 1 2002 KC1 Fig 1 0 2 Hz0 1 202 2H 2e 2C Cl 2e Cl Hz0 HCI HCIO Fig 2 KO1 HzO Fig 1 Fig 2 C1 Cl2 HzO HCD CIO
36. 37 6 i No 2899 96 022 as Vo1 6 No 2 1998 p 63 68 8 4 4 85 2003 p 33 14504 2004 p 25 p 84 97 No GT 06160 88 2002 No 18 NaC KC 1 6G1A0 T 37078 37 2 2 2 5
37. S 9 Mix 20 40 809 22 5 45 90 90 7 24 48 90 20 40 80 22 5 45 90 DON D6
38. 20 1 13 2 i 18 1994 pH 2 68 41 1 ppm Sprague Dawley Crj CD 5 115 4 122 4 g 100 3 107 7 g 5 14 1
39. 17 24 1994 8 48 3 p179 181 1994 Received April 22 1994 pH 2 24 30 50 ppm Salmonella typhimurium TA100 TA1535 TA98 TA1537 Bscherichia co7 WP2 uvrA GS 9 Mix 62 5 1000 gp plate 5 1000z plate
40. i 76 pH2 56 45 ppm 6 SPF 25 20 30 3 2 i 77 pH2 47 48 ppm 20 30m kg 30 3 i 78 pH2 53 40 ppm 5 SPF 30 ml kg
41. We 5 0 vs 16 24 30 16 24 30 Vo1 48 3 1994 p 179 181 3 25 26 27 28 26 29 28 30 3 1985 p 403 407 38 1985 p 100 103 39 2 49 El 28 No 42 28 NaCl NaOH KC1 KOH MSDS 2 50 2 25
42. 39 2005 2 pH2 6 2 7 33 35 mg l 10 24 22C 2 LC50 mg l h 24 48 72 96 LC50 11 000 7 800 7 400 6 800 Binominal NOEC 96 NOEC 4 600 mg mg l 24 48 72 96 1 000 0 0 0 0 2 200 0 0 0 0 4 600 0 0 0 10 000 40 80 90 100 22 000 100 SAR 46 000 Se 100 Od a et 0 0 0 0 49 SR 24 48 72 96 mg l 1 000 n a d n a d n a d n a d 2 200 n a d n a d n a d n a d 4 600 n a d n a d n a d n a d n a d de 10 000 n a d n a d e s U d D 22 000 EE RU 46 000 es 5 n a d n a d n a d n a d n a d no abnormalities are detected dc discoloration e s erratic swimming u d p upside down position
43. HzO HC1 HC1O HzO Oz H Na K 1 1 NaQl KC1 NaOH KOH NaCl K
44. pH 11 3 50 1 15 pH 2 6 85 40 mg kg 10 pH 11 6 12 0 800 100 kg 1 40C 6 11 pH 2 7 40 mg kg 30 ml 4 12 pH 2 1 20 30 mg kg 300 V10 a 4
45. NaCl 100 0 85 0 0 48 659 50 44 yy 68 pH 2 48 40 ppm SPF 1 4 i 69 pH2 58 46 86 ppm 3 12
46. 1 0 1 1 Vol 38 4 2000 6 52 1 1 5 2 5 1 2008 2004 20 70
47. 29 1995 pH 2 6 45 50 ppm DON D6 S 9 Mix 5 10 20 100 2 5 25 5 10 20
48. 30 3 0 2 N 47 i 79 pH 2 42 2 51 45 52 ppm SD 7 1 10 30 60 30 30 5 12 90 48 8
49. 47 57 65 2 2 2 1 ppm 33 61 62 63 64 70 71 72 80 1 2 97 35 2004 pH 2 68 23 5 mg kg 75 mm 10 cm 400 g
50. 16 9 2 2000 or and and or not 8 6 87 N Cl QN Q SH pH 8 CIO Cls CIO C1O
51. 2004 pH 2 67 24 1 mg kg rr 4 500 ml cm2 A 40 B 90 C 840 D 1150 Oh 24 1 0 5 h 12 9 12 9 11 0 9 6 lh 8 30 6 84 4 69 0 18 2 h 4 76 3 55 2 43 N D 3 h 0 68 0 69 0 70 N T 4 bh 0 12 0 18 N D N T 5 h N D N D N T N T mg kg N D Not Detected N T Not Tested 36 D
52. 19 1995 pH 2 52 60 ppm ICR 4 19 7 23 4 g 1 5 14 7 14 mlkg 4 0 5 9 8 9 13 8 20 0 20 0 ml kg 8 a _ mVkeo ml kg 09 20 0 mkg 3
53. 3 5 5 2 1004 plate 2 5 2 68 100 plate 20 plate 8 9 z1 Mix plate TA100 mA1535 WP2 TA98 TA1537 uvr A 100 117 16
54. 38 mg kg 300 ml 3 7 pH 2 8 0 60 mg kg 200 1 10 a 6 pH 2 52 49 3 mg kg 8 50 ml 12 2 1 1 pH 2 7 9 20 60 mg kg
55. 30 25 20 15 10 6 19 50 59 pH 2 45 50ppm L929 10 90 8 90 ry 60 pH 2 45 45 ppm WI 88 Chang L929 C 50 25 12 5 6 25 3 12596 3 41
56. 0 2 pH 6 5 10 60 mg kg 1 2 3 1 3 lt Ui 90 28 page 11 11 14 14 18 32 35 36 39 40 49 55 Clz
57. HzO Oz HH Na K 1 1 NaC1l KC1 NaOH KOH NaC KCl
58. 54 mkg 4 mi ke mike 54 mkg 4 16 iv 23 1991 pH 2 43 45 ppm Wistar 7 105 117 g 5 14 15
59. DON D6 28 CT x 24 DD 20 48 0 3 5 1 0 10 24 3 2 20 0 2 5 0 10 48 0 D 20 0 0 MMS 11 48 0 39 es Mix 2 0 20 3 5 3 1 10 0 2 20 SS 0 10 0 1 20 3 0 10 3 41 CP 10 0 0 1 g plate MMS Methy1 Methanesulfonate CP cyclophosphamide 29 30 21 22 1998 pH 2 42 50 ppm DON D6
60. pH 1000 2000 mg kg 20 60 mg kg 8 45 46 80 1 2 47 39 40 41
61. 4 pp 619 626 1997 pH 2 45 2 53 40 mg kg Sprague Dawley 1 6 7 7 8 183 1996 90 2 8 163 0 g 157 7 g 192 2 g 195 5 g 560 8 g 543 0 g 316 7 g 337 0 g
62. 0 48 0 85 88 60 67 pH 2 47 48 ppm a FDI 0 85 NaQ1 5 0 85 NaCl 60 5 Bh 0 D 0 D x100 Sn 0 D 0 D 5 45 60 77 b Parpart 13 NaCl 0 85 0 80 0 75 0 70 0 65 0 60 0 55 0 50 0 45 0 40 0 85 0 30 0 20
63. 24 48 1 000 0 0 1 500 5 15 2 200 70 70 3 200 100 4 600 100 ee G800 oo ODN pe 0 0 52 42 2005 2 pH 2 7 34 mg l 1X104 cells m1 100 r min 23 2 EC50 mg RbC50 0 72 hr ErC50 24 48 hr ErC50 24 72 hr 0 3 600 2 2 700 2 2 800 4 700 2 100 3 400 1 Doudoroff 2 NOEC mg NOEC 0 72 hr NOEC 24 48 hr NOEO 24 72 hr 1 000 1 000 1 000 1 1 Dunnett c 0 05 X104 cells m1l 24 48 72 mg l 32 4 01 19 57 101 65 100 3 58 19 48 95 70 320 3 26 16 92 78 74 1 000 3 38 16 45 76 58 3 200 1 50 2 61 3 06 er 00000 Nn LG Ee 0 98 4 13 16 15 77 33 OS ag A 0 72 hr IA 0 72 hr 32 17 256 400 27 100 16 420 000 21 320 13 691 600 1 1 0
64. 48 72 54 pH 2 42 51 ppm Hartley 17 0 25 ml 1 8 5 24 0 5 my 0 25 m 0 5 ml 55 pH 2 48 2 49 30 ppm Hartley 26 1 1 0 1 ml 48 2 0 1 ml 24 48 72
65. 50 40 2005 2 pH 2 7 35 mg l 20 5 100m1lx4 20 1 LC50 mgD 8 LC50 95 3 200 em Binominal mg 1 000 0 1 500 2 200 0 3 200 50 4 600 100 ee 6800 100 0 51 41 2005 2 pH 2 7 31 28mg 1 20 5 100m1x4 24 20C 1 EC50 mg D 24 EC50 48 EC50 2 000 1 900 1 800 2 200 1 700 2 100 Probit NOEC 48 NOEC 1 000 mg l 9 mg
66. 2 10 1 10 4 10 1 10 GPT 90 31 31 2 44 95 JOIS JST 16 9 2 2000 or and 62 17 Q 32 61 62 63 64 69 70 71 72 80
67. HHC1O Nar CIO Cl HTC1O C1O pH 2 2 86 0 53 8 69 8 92 9 1 100 3
68. 2 5 pH 2 7 40mgkg 3 52 20 44 mg kg 1 2001 6 2 2002 6 4 1 5 2 5 1 2 58 8 1 69 8 2 2001 8 29 92 9 2 2002 9 4 pH 2 5 2 7 10 3 1 JOIS JST 16 9 2 2000 or and 62 17
69. 42 0 2 1 1600mg l 0 16 No 5 H12 2 16 2 3 H14 p 24 28 170 177 4 4 29 4 2003 p 203 209 LM
70. 67 AF 2 0 1 123 2 0 406 a NaNs 0 5 379 ICR 191 1 1252 2AA p gplate AF 2 2 2 fury 3 nitro 2 furyl acrylamide NaNs sodium azide ICR 191 2 methoxy 6 chloro 9 3 2 chloroethy aminopropylamino acridine 2HC 2AA 2 Aminoanthracene 23 27 1993 pH 2 46 48 ppm _ Salmonella typhimurium TA100 TA1535 TA98 TA1587 Bscherichia co WP2 uvrA GS 9 Mix Ames 1 1000z1 plate 7 500 10001plate WP2 uvrA 1000 plate 500pr1plate
71. 1 4 2 7 25 100ml No 9 10 70C 5 No6 7 No 1 No 22 25 20C 1 13 No 4
72. 00 13 348 800 2 3 200 753 600 94 a 10 000 123 600 99 13 546 800 mg 24 48 hr Im 24 48 hr 24 72 hr Im 24 72 hr 82 0 06592 16 0 06728 10 100 0 07043 24 0 06832 12 320 0 06861 21 0 06633 9 1 000 0 06591 16 0 06498 7 3 200 0 02250 60 0 01444 76 Ap 10 000 0 00681 88 0 00359 106 0 05663 0 06097 54 gt 28 90 43 31 31 2 44 1
73. 0ml 4 pH 2 7 40 mg kg 50 100 ml 1 60C 1 20 5 5 4 2 3 4 5 pH 2 7 20 60 mg kg 200 ml 1 6 pH 2 54
74. 1 633 AF 2 0 1 ER NaNs 0 5 291 TCR 191 1 i 0 5 8 1 703 A 2 184 10 WP2 uvr A 47 TA98 22 27 TA1537 10 12 9 11 13 11 7 15 16 14 13 11 15 16 AF 2 2 2 fury 3 nitro 2 fury acrylamide NaNs sodium azide 1CR 191 2 methoxy 6 chloro 9 3 2 chloroethyD aminopropylamino acridine 2HC 2AA 2 Aminoanthracene 4A growth inhibition 19 i 25 1994 pH 2 55 49 35 ppm Salmonella typhimurium TA100 TA1535 TA98 TA1587 Escherichia co7 WP2 uvrA S 9 Mix 6 8 100 plate 5 1 100 glplate
75. 21 25 12 NaCl HC 100 98 14 30 27 9 6 8 119 16 37 17 7 12 5 99 15 27 23 10 25 123 14 29 21 7 ot CD CD 23 8 115 12 25 24 11 NaCl HC1 0 01 526 154 Ox 2 0 1 514 NaNs 0 5 324 9AA 80 lt 1103 NaCl hydrochloric acid buffer pH 2 6 py g plate AF 2 2 2 fury 8 nitro 2 fury acrylamide NaNs sodium azide 9AA 9 aminoacridine 2AA 2 Aminoanthracene 21 i 26 1995 pH 2 52 60 ppm Salmonella typhimurium TA100 TA1535 TA98 TA1587 Bscherichia co WP2 uvrA GS 9 Mix 1 200 plate 6 200 500 plate
76. C1 49 0 2 48 56 KC1 89 pH pH pH2 7 10 60mg kg 50 1 2 82 83 84 85 86
77. H pH 2 5 20 mg kg 50 mg kg 16 5 52 15 1 1 10 pH 2 5 2 7 20 40 mg kg 1 5 2 5 1 2 pH 2 5 2 7 20 44 mg kg 48 88 19 20
78. g 6 3 0X3 0 cm 1 5 ml 4 5 4 1 65 pH 2 61 46 ppm 37 8 5 30 60 576nm 5 80 60 40
79. p 25 27 5 A 1998 p 28 29 5 12 3 1 H14 p 153 165 6 i Vol 36 4 1998 p 245 249 6 IP 2 Vo1 38 1 2000 p 33 38 N 3 pH Vol 38 4 2000 p 263 271 4 pH 13 NO
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