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1. 16 SF FDG 1 28 292. 16 SF FDG 1 28 29 2 2 2 LSE FDG 7 1 a
3. oS 3 NS i 2 2 FN 320 ls EY 1 RADIOISOTOPES Vol 58 No 6 a ep oe nt 1
4. 84 Jun 2009 2009 303 1 1 1 1 CIDG 1 3 I IL SO EEO
5. 40 90 2 2009 311 2 1
6. SK603 90 Jun 2009 2009 309 4 2009 11 5
7. PET 3 2 Jun 2009 c 2009 321
8. b 3 a 1 1 10 b 3
9. M1 50 ooc M1 M50 ooo TS TL1K ooo Dualex SP ooo 18 Gx38 mm ooc 20 Gx70 mm ooo 20mLV20 9p9 UV ea WASTE RNN Po 200 mL ooo 500 mL ooo 1 2 O
10. 20 mL 20 mL 4 4 10 mmolL 4 5 3N Op gw N SN 4 6 3N NN BN LIN 0 22 um 4 7 RE 20 mL
11. 13 PET 3 PET 3 c
12. 2009 4 2 F JFDG 79 298 3 4 5 6 7 8 9 RADIOISOTOPES Vol 58 No 6 FDG 8F FDG LSF FDG FDG CarboPak PA 1 4x250 mm CarboPak PA 1 Guard 4x50 mm 220 mmolL 0 2 mL FDG 25
13. 1 1 1 6 6 2 2 2 1 50 cm 2 2 50 cm 3 4 H 5 pH pH pH 6 7 7 1 RN DE RT OD WEE 7 2
14. 1 2 2 2 D FEF GN 5O CO C O G5F C 2 3 4 5 6 7 8 3 lt 292 RADIOISOTOPES Vol 58 No 6 4 7 WE 5 8 CGC 6 13 7 1 2 2 D 8 WE E FDG 9 2 N 3 GO
15. 119 122 98 0 2 4 1 5 6 1 2 20 1 ABX M 103 GE 86 Jun 2009 2009 305 b GSF 8O LO H O ooo ooo ooo 3
16. ea i 3 a 1 1 10 10 b
17. 3 3 5 3 1 10 mmol L EN 0 22 gm 3 2 O g N BN 4 4 1 3 3 N 3 4 4 2 100
18. 0 25 0 5 99 75 99 5 5 1 O OO OOOO b 8O ooc 1 c O O
19. PET 2009 329 3 PET 3 3
20. SK 603 2009 11 pH pH Whatman Type CF 95 5 FDG 0 4
21. 312 RADIOISOTOPES Vol 58 No 6 pH 1 PET 3 3
22. 7 9 1 N 2 3 2009 2009 F 4
23. 1 1 1 3 3 2 FDG 1 FDG 89 308 RADIOISOTOPES Vol 58 No 6 2 2 1 SF FDG 50cm 2
24. 3 5 Sep Pak Plus tC18 Sep Pak Alumina N 0 22 um 4 4 1 92 100 mL NaOH 536 mg NazHPO 3 204 g 4 2 FE EO HzO O p n SF PE 4 3 Sep Pak Plus tC18 Sep Pak Alumina N 4 4 EF FDG 6 4mL 1 molL 2 mL 10 mL 30 mg 4 5 FE FDG
25. 1 2 FIFDG 1 3 SF FDG FDG 1 4 WTFIFDG 2 2 1 50 cm 2 2 50 cm 3 4 H 5 pH pH pH 6 7
26. K CO 1 5H 0 1 mol L 1mol L FY ooo ooo ooo QMA 5 I a hi 67 A Ns 1C ooo 76 Jun 2009 2009 295 6 37 PS 2 ooo S 8 B ooo FDG
27. 9 CIDG CarboPak PA 1 4x250 mm CarboPak PA 1 Guard 4x50 mm 220 mmoLL 0 2 mL CIDG 27 4 1 OOOOOO OOOOOO OOOOO 2 SF FDG 91 310 RADIOISOTOPES Vol 58 No 6 CH F O 28 30 mg NO OOIHzO FP FP 12 13 mL 20 mL pH 2 mL
28. 2 2 1 50 cm 2 2 cm 50 3 4 HMV 5 pH pH pH 6 7 7 1 7 2
29. HEPA 2 a b 3 a 1 1 10 b
30. 2009 293 1 mL 1 Se 2 2 D PfF FIFDG ooo NR Ge GBq ooo MBq o0 GBq 1 mL 17 21 mL 2 OOOOOO FDG OOO OO 3 1 a CisHieFs0128 ooo ooo ooo 119 122 C 98 0 2
31. 0 oooooo RI oooo oooo SO 1 O 2009 4 2 40
32. 1 23 mL 2mL 2 3 37 MBq zmol 4 105 115 5 6 7 150 EU 8 9 pH 5 0 8 0 10 511 keV 11 511 keV 1022 keV 1 12 95 13 18 1 2 000 ppm 1 13 2 1 200 ppm 1 13 3 164 ppm 1 18 4 10 ppm 18 5 CIDG 40 ppm 1 1 3
33. 99 5 vol MAN 500 mL NR 3 1 96 Jun 2009 2009 315 CN OOOOOO OOOO b GN
34. M1 50 ooo M2 50 ooo M2 M100 ooo F2 M100 ooo FF2 250 ooo X1 50 ooo X1 120 ooo TS TL1K ooo Vented Millex GS ooo 18 Gx38 mm ooo 100 mL ooo 500 mL ooo 1 105 324 RADIOISOTOPES Vol 58 No 6 2 2 1 1 11 15 3 2 1
35. 3 O 4 5 2 6 4 3 RI O 1 2
36. 4 5 1 GSF OOOOOO OOOO c SF FDG ooo 229 Kryptofix 2 2 2 99 8 H20 10 ppm 99 995
37. c 111 E
38. 1 1 2 2 D TE EF FDG 2 1 mL 1 6 5 2 2 pD 0 45 mL 12 13 mL 1 mol L 0 09 mL 2 mL 0 45 mL 10 mL 1 100 mL NaOH 536 mg NazHPO4 3 204 g 2 OOOOO FDG O OO OOOOO 3 1 a CFO 8 2 ooo ooo ooo 3
39. 1 3 O O O OOO 1 4 1 2 1 3 STEP1 4 STEP 1 STEP 2 STEP 3 STEP 4 5 INJECTION CHECK STEP
40. YY HO gt 98 150 7S cm 4 YY 5 O ooo ooo ooo CE
41. CarboPak PA 1 4x250 mm CarboPak PA 1 Guard 4x50 mm 220 mmolL 0 2 mL CIDG 27 2009 I 8 25 9 1 Kryptofix 2 2 2 0 38 80 Jun 2009 _ 4 1 2009 299 FDG 2 SF FDG Nol NO H 0
42. 5 2 5 6 1 120 480 MBq 2 8 MBq kg 40 90 2 2 1 83 2009 301
43. O 12 1 a 1 a b PET 3 HH 110 Jun 2009
44. 2 3 ooo ooo 38 0 25 0 5 0 8 gt 99 9999 10L ooo gt 99 9999 10L ooo gt 99 9999 10L ooo 1 150 OOOOOO RI OOO O OO 2 3 104 Jun 2009 d O e 2009 F
45. SK 603 E 11 99 318 RADIOISOTOPES Vol 58 No 6 4 pH pH Whatman Type CF 5 Shim Pak 3 9 mmx 150 mm 5mmolL 3N 4 5 mL Nova Pak C18 3 9 mmx 150 mm 5 mmolL PIC B 8
46. 1 1 1 2009 RADIOISOTOPES 58 221 245 2009 2009 RADIOISOTOPES 58 247 289 2009 3 3 O 2009 RADIOISOTOPES 58 291 442 2009 4 FDG PET
47. 1 1 1 1 3 3 98 Jun 2009 _ 2009 317 2 2 1 1 1 N 50 cm 1 2 N 1 3 HN
48. 95 5 FDG 0 4 0 1 vol22 FDG 0 6 6 Bondapak carbohydrate 3 9 mmx30 cm 85 15 1 mL FDG 6 5 7 TSG 1 15 SHINCARBON A60 80 3 2x3 100 mm 00 180 FID 180 Nz 70 kPa 4 1 3 4 6 7 8
49. 1 c ooo ooo 2 ooo ooo a 4 i ooo yy ooo a _ A aa 0 ooc ooo
50. 1 5 1 O 2 O 3 4 5 Jun 2009 1 6 0 25 0 5 N d n O O O O PO OO sO 5O O 400 MBq
51. SE SE QMA IC HH PS 2 3 1 QSF 2 35 mL 1 mol L 15 mL 0 3 mol L 3 2 mL 28 mg 7mL 2 2 2 200 mg 0 2 mL 2 2 2 0 7 mL 4 100 mL
52. b PET 3 HEPA 0 2 a b 2 13
53. E 13 13 4 3 13 5 CIDG 1 F FDG
54. 0 1 vol FDG 0 6 Bondapak carbohydrate 3 9 mmx30 cm 85 15 1 mL FDG 6 5 TSG 1 152 SHINCARBON A60 80 3 2x3 100 mm 90 180 C FID 180 C Nz 70 kPa 4 1 3 4 6 7 10 CIDG 11
55. 9 1 O 30 2 3 328 10 11 1 gt 120 480 MBq min 2 8 MBq kg min 0 gt 480 4 800 MBq 8 80 MBq kg 1
56. PET 3 c 2 CIDG I 3 IL O HzO 4 O HO 5 CHCN Ml NazHPO4 WM
57. 5 QMA Sep Pak Light Accell QMA Waters 6 IC H Alltech Maxi Clean Cartriges IC H 7 PS 2 Sep Pak PS 2 Waters 8 Waters Sep Pak Plus Alumina N 9 MILLIPORE Milex GS 10 MILLIPORE Dualex 1 O e PE EFDG 3 14 lesoc li 2 Chloro 2 deoxy D glucose ooo oe 1 77 296 2
58. SK 603 3 2009 11 4 pH pH Whatman Type CF 107 326 4 RADIOISOTOPES Vol 58 No 6 5 PEG 20M Carbowax 20M 0 53 mm x
59. 2 2 2 SF FDG FDG OO 7 1 a RADIOISOTOPES Vol 58 No 6 1 b PET HEPA 2 a
60. a GN O HzO ooo OOO OOO 3 J A a 2 8 3 99 5 CsH OH ooo ooo ooo 3
61. PET 3 b 94 Jun 2009 _ 2009 313
62. O Rt 2 2 1 RADIOISOTOPES Vol 58 No 6 2 2 O
63. 2 17 10 42 2005 16 PET FDG PET 2005 1 GO Hz O 2 1 mL 1 0 oo MBq co GBq oo MBq oo GBq 1 mL 8 12 mL 2 OOOOOOO OO 3 103 OOOO 322 RADIOISOTOPES Vol 58 No 6 1 a sO 1 ooo
64. 4 HEPA 2 a b pH 3 a 1 1 10
65. 7 1 511 keV 1022 keV 1 95 2 ppm 7 2 7 3 1 3 1 3N 10 3N BN 1 3N 3N 1
66. 1 2009 RADIOISO TOPES 58 291 442 2009 2009 RADIOISOTOPES 58 MV FDG 221 245 2009 PET 2 2 17 10 2009 RADIOISOTOPES 58 247 289 2009 85 42 2005 16 PET FDG PET 2005 304 RADIOISOTOPES Vol 58 No 6
67. LOAD Sep Pak Plus tC18 Sep Pak Alumina N Jun 2009 SF FDG LOAD 4 6 FE FE SF FDG 4 7 E FDG SF FDG 0 22 um 12 13 mL 4 8 5 5 6 1 120 480 MBq 2 8 MBq kg
68. O 1 O O 1 1 3 3 1 1 1 106 Jun 2009 2009 325 2 2
69. 40 60 3N 1 25 mL 6 4 3N 1 O OOO 2 SN 10 mmolL NN FNI 5 40 mL 1 50 mL 29 gL 2 NN
70. I EE Me 1 2 20 1 ABX b GSF 6 1 Y OlHzO 2 ooo ooo ooo 75 294 RADIOISOTOPES Vol 58 No 6 3 H O gt 98 150 gS cm
71. 16 7 g 1 molL 3 3 1 EO HzO O n FEF WE 3 2 F QMA 3 3 QMA PF Kryptofix 2 2 2 81 3 4 3 5 3 6 SF KF 0 3 molL 300 FDG CH PS 2 0 22 um
72. 2009 4 oO 109 FE 9 3 O 4 5 7 8 6
73. 3 3 BE 1 78 3 FDG Jun 2009 2009 297 2 2 1 1 1 SF FDG 50 cm
74. 20 mL 4 3 x 5 6 6 1 101 Jun 2009 2009 319 6 2 5 6 1 240 4 800 MBq 4 80 MBq ksg 2 2 1
75. Prepara tion 4 4 MI gt 82 RADIOISOTOPES Vol 58 No 6 4 7 9 mL 4 8 QMA QMA IC H PS 2 4 10 2 2 2 20mg 0 88mL 0 68 mL
76. 7 1 7 2 7 3 7 4 8 7 5 3 7 6 CIDG W 7 7 Kryptofix 2 2 2 1 F FDG
77. 10 4 L CGC 11 5 CC 12 6 CGC 1 2 2 D 7 GT GF LE FDG 8 GC 14 2 CN 15 3 5O 4 C 16 5 CC 6 C 17 1 OO OO OO OO OO OO 2 1 2 2 p F G 1 2 2 D FE E FDG 2 74 Jun 2009
78. O OOO c SF FDG ooo pH ooo 99 NasHPO V 1 JIS NaOH V 2 HCI ooo 1 mol L V 3 1 100 mL NaOH 536 mg NazHPO43 204 g 2 87 306 RADIOISOTOPES Vol 58 No 6 d t a 99 Ni ON N
79. 20mg 1 3 mL 0 7 mL 0 3 mol L 4 mL 5mL 4 11 Check before synthesis 4 12 F 4 9 Jun 2009 LE F FDG 4 13 F FDG SF FDG 0 22m 4 14 5 5 1
80. 2 2 3 150 EU E 6 511 keV 1 7 7 1 511 keV 1022 keV 1 7 2 99 1 1 3 1 1 PET O 2 SO O
81. 2 NaOH 3 1 molL HCI 4 CHiCN 2009 5 AAD7O7SO7OPpS 58 221 245 6 C18 2009 7 SF EFDG FDG 8 PET V 1 FDG 2 17 10 42 2005 2 N 1 1 N N NH 2 1 mL 1 FPN oo MBq oo GBq oo MBq oo GBq 1 mL 9 11 mL 95 314 RADIOISOTOPES Vol 58 No 6 2 OO OOOO O OO 3 1
82. SF FDG FDG F FDG 2 E TR B PP 50cm 50cm pH Type CF pH A E Whatman E
83. 10 mL 4 mL FIFDG 10 mL 5 mL 1 1 C18 1 GF 2 100 mL NaOH 536 mg NazHPO 3 204 g 3 3 1 O HzO O p n SF PF 3 2 F 4 4 3 3 1 3 4 6 O 2 O 8 D 3 4
84. 2 LE FDG 2009 I 4 FDG F FDG SF FDG E FDG CarboPak PA 1 4x250 mm Car boPak PA 1 Guard 4 x 50 mm 220 mmoLL 0 2 mL FDG 25 3 BB
85. ooo ooo ooo gt 99 9999 1 2 Waters Sep Pak Plus Accell CM 3 MILLIPORE Millex GS 4 MILLIPORE Dualex 5 97 316 RADIOISOTOPES Vol 58 No 6 2 2 1 10 mL 1 mL 9 5 10 5 150 EU 2 2 511 keV 1
86. 2 1 RADIOISOTOPES Vol 58 No 6 19 mL 2 mL 37 MBq zmol 105 115 150 EU 3 5 0 8 0 511 keV 511 keV 1022 keV 7 8 2 000 ppm 1 7 4 164 ppm 1 Ei 7 5 95 10 ppm 7 6 CIDG 40 ppm 7 7 Kryptofix 2 2 2 1 40 ppm 1 1 2 1
87. 8 5 MILLIPORE Millex GS 6 MILLIPORE Dualex e F JFDG 1 2 Deoxy 2 fHuoro p glucose oo 2 2 Chloro 2 deoxy D glucose oc 3 oo 4 oo 5 oo FT 2 Deoxy 2 fluoro D glucose SIGMA F 5006 2 2 Chloro 2 deoxy D glucose ABX 88 Jun 2009 2009 307 2 2 1
88. FDG oooc ooo ooo 9 ooo 9 ooo 2 wT i a 18 1D gt eg O ooo 11 ooo ooo gt 99 9999 1 2 3 Kryptofix 2 2 2 Merck 4 F Kryptofix 2 2 2 0 3 molL QMA
89. 3 7 4 4 1 FE OO HzO O p n SF WE 4 2 QMA QAMA QMA 10mL 60 mL 4 3 IC H 40 mL PS 2 10 mL 40 mL 4 5 0O Waste Check before preparation
90. 30 m 40 C 250 200 50 guL 99 sO O 1 OO 2 2 1 0 25 0 5 CO O 2 2 O O 2 3 O O 1 1 1 O O 1 2 O O
91. N V 4 le EE a a ooo 2 MM ooo ooo a a 9 ooo V 5 V 0 i kk 8FIFDG ooo V 7 NN ooo ooo a ooo ooo V 8 ooo gt 99 9995 1 2 Waters Sep Pak plus Alumina N 3 C18 Waters Sep Pak plus tC18 4 WEF FDG SFIFDG
92. RADIOISOTOPES 58 291 442 2009 2009 113 8941 2 28 45 Key Words EDG BO water 9N ammonia 1C L methionine NC sodium acetate 1C choline 18F sodium fluoride TC flumazenil drug product standard code manufacturing control standard code manufacturing hygiene control standard code quality control standard code manufacturing direction manufacturing record quality record 2009 gt Reference Materials for Standards of Compounds Labeled with Positron Emitting Radionuclides Ap proved as Established Techniques for Medical Use 2009 revision Nuclear Pharmacy Workgroup Subcommittee on Medical Application of Positron Emitting Radionu clide
93. s Medical Science and Pharmaceutical Com Association 2 28 45 Honkomagome Bunkyo ku Tokyo 113 8941 Japan 2008 11 mittee Japan Radioisotope 6 73 2009
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