第2次答申
Contents
1. 2 WHO WHO2. 3 i
3. 1 2 1 1 4 0 05mg 1 2 1 2 0 04 mg 1 0 002mg 1 1 4 0 05mg 1 3 4
4. 16 0 002mg 1 1 4 16 18 2 10 16 1 10 16 13 19 1 10
5. 9 2 6 1 4 Tenax GC Tenax TA 10 2 6 1 4 6 180 280C 10
6. Ki to 1 4 10 100mg 1 10ml 100ml 1 1 3 2 4 1 4 h 0557 A 3 A 4 1 8891 1 8034 1 8461 5 1 4 1gD 1 4 6 1 4 100mg 1 1 4 10ml 100ml 2 100mg 100ml 7 h 2 3
7. 18 19 70 1209 20 21 2 5 0 25 25 ug ml 4 1 0 05 5 ngl
8. 4C 16 16 4 1 0 5 25 ml 5 ml d 3 0 5 ug 1l 17
9. 14 8 15 1 16 2 26 2 0 9 3 0 2 0 12 2 5 2 1 3 1 6 2 1 7 1 0 2 1 9 4 2 2 1 9 1 5 8 9 1 0 1 1 1 2 1 1 3 mg L
10. i 2 16 2 2 5 ra 1
11. 4 500 t 19 15509 1 0 05mg 1 0 05mg 1 1 113 WHO 2 0 05mg 1 3 1 USEPA EU PRTR 19 46 169kg 46 169kg 135 508kg a OS 10 2 1pg kg 21 day 0 0
12. 15 5 14 8 15 11 16 2 1 16 1 4 5 p 16 1 4
13. 20 40 ml ee SN wo i 13 3 14 4 0 5 ng 15 0 53 mm 0 53 0 75 mm 30 120 m 3
14. Yamazaki 1994 10 2 1 g kg 50kg 2 1 day 0 05mg 1 3 1 4
15. 3 1 16 16 16 17 18 1 19 1
16. m z62 64 d 3 m z65 67 4 21 d e d 3 d 3 5 17 tH
17. 10 56 130 164 1 4 8 5 5 9 1 4 1 2 2 4 6 12 28 5 9 1 9 3 13 1 0 2 6
18. lt 5 3 1 ROSE 11 2 1 WHO 2003
19. 99 9999vol1 40cm 40C 1 40 150 SC 200 3 6 7 50 1209 8 14 9
20. WHO 2 1 16 1 4 16 WHO 20
21. ml 2 K012 5 1 4 3 0 2 ng 4 5
22. 3 300ml 2 4 1 200ml 10 50ml 2 11 10ml 12 10ml 20 13 8 5ml Iml 1ml 14 10ml 3 200ml 30m 1 2 4 200ml 50l
23. 0 02mg 0 04mg 0 002mg L 4 2 405 H16 0 0056 H17 0 0031 H18 0 0034 H19 0 0025 a 0 0005 0 0025 0 0019 0 0005 0 0004 0 0002 0 0011 0 0003 0 0004 0 0004 0 0004 3 H19 1 4 0 05mg L 2 2 485 Hig 2 83 10 0 002mg L 145 1 097 1 4 0 05mg L 14 906 H16 H16 H16 H16 H16
24. 1 2 1 2 4
25. 2 b c e 40 250 ml 6 KK0557 A 2 A 3 105 2 3 2 7 8 a 0 25 ml 105 2 3 20 40 t
26. 14 2001 1 4 43 1046 NITE amp CERI 2005c ck Guy 5 15 WHO 3 1 Guidelines for drinking water quality First Addendum To 3 9 ed Vol 1 Recommendations World Health Organization 2006 16 Yamazaki K et al 1994 Two year toxicological and carcinogenesis studies of 1 4 dioxane in F344 rats and BDF1 mice Proceedings of the Second Asia Pacific Symposium on Pnvironmental and Occupational Health 193 198 17 50 LOAEL Lowest Observed Adverse Effect Leve1 NOAEL No Observed Adverse Effect Leve TDI Tolerable Daily Intake NITE Nationa1 Institute of
27. 8
28. 3 CAS No 75 01 4 CH C1 62 5 RR A WHO 1999 1 40 WHO HH i WHO H 10 1 4
29. d 3 0 5 ng 1 19 7 8 10 14 17 19 d 3 6 d 3 ng ng 22 1 1 E 22 hg H ng d 3 20 ng d 3
30. 25 2001 42 BCF 1 mg 1 10mg 1 0 3 0 7 0 2 0 6 1976 i 37mnHg 25C 2 6 69 9 6 2 NO 1 03 20 C 4 0 29 Pa m3 mol 20 C E
31. 3 4 1 3 5 d 3 d 3
32. 2 2 1 9 1 CD 1 2 2 1 2 3 4 1 1 2 WHO 3 4 12 5 DU 12 1 2 3 1
33. RS E E Gango11i 1999 GDCh BUA 1989 3 28 10 2mg BCF 1 BOD 16 3 NITE amp CERI 2005a 1ogPow 2 04mg 1 1997 1 46 1997 10
34. 0 3 5 mm 50 300 mm 2 6 1 4 177 230 pm 230 500 pgm 250 500 pm 250 500 pum 9 10 20 40 ml fj 30 60 11 20 40C 1 180 280C g 99 9999 vol1 1 12 20 60 ml
35. 26 27 11 11 WHO 3
36. 3 4 4 1 2 KO0125 5 1 5 2 5 3 2 KO125 5 1 5 2 5 3 1 5 1 5 2 5 3 1 ECD 5 3 2 FID 3 1 1 4 3 2 KO125
37. 16 1 43 PRTR 0 05mg 1 3 2
38. lt gt 5 http www jisc go jp ml Ww
39. mg L mg L 109 1 4 16 1 1 WHO 1 2 1 1 1 WHO 20 0 002 0 05 0 0004 0 02 5 0 0002 19 0001 0 2 6 0 3625 00001 0O 978 00001 ooooil 000 1 0 002 0 1 0 04 0 04 001 Hi9 002 Hi6 005 Hi7 0 0002 H16 0 002 H17 0 002 H18 0 001 H19 002 H16 0 002 H19 0004 H16 ol olololololo 0 004 0 04 0 005 0 oo5 r Fa er bri Fri lo elelelelelel ls iol Ielele
40. 1 g l 14 d 8 100mg 100ml 2 8 100mg 10ml 100ml 4 9 1 g 1 100ml 4 100mg 5 h qd E 2 1 1 4 2 20C 3 0 005 200ml 10ml 0 1 30
41. 1 12 5ml 10ml 5ml 10 20 13 14 5m 10ml 15 1 4 70 120 50 1200 5 14 0 200ul 5
42. 13 0 32 0 53 mm 1 3 3 14 a 1 0 2 0 32 mm 4 Ee KK1107 30 E 200 25 120 m 15 0 1 3 um 99 9999 vol
43. 902 431t 15509 7 40 Freitag 1985 9 0 9 20C 4 8 81g 1 25 2 820 Pa m mo1 24 3 141 659t 19 1 0 002mg 1 0 002mg 1 0 002mg 1 a 1 77 2 WHO 0 005mg 1 2 3 0 0003mg 1 USEPA 0 002mg 1 EU 0 0005mg 1 4 PRTR
44. 10 1 10 17 58 10 16
45. co ololo i 0 02mg KrPS EE H17 H19 4 H17 H19 eh 7 H19 H17 H19 mg L 10 mg L 3 a 41 1
46. 60 15 5 a 1 2 1 1 4 88 58 1 4 d 8 96 64 4 174 95 20 20 10 11 1 50
47. 19 7 665kg 7 665kg 303 341kg 5 Feron 1981 10 0 0875 w g kg day 50kg 21 day 0 002mg 1 2 1 4 3 1 4 CAS No 123 91 1 C4H 0 88 1 U S NLM HSDB 2001 28 BOD 0 1976
48. 50 ml 3 000 hg d 3 d 3 3 4 5 7 1 ug m 50 90 ml 100 ml 1 ml 100 ml 1 1 3 1 1 3 2
49. lt 2 WHO 1 4 WHO 3 1 TD I 20 0 05mg 1
50. 12 35 230 0 5 4 20 40 cm 40 2 10 230 es 150 280 C b SIM 70 V RI fy 6 30 pm 3 5 E7 3 E8
51. 4 4 C 1 5 VOC 4 1 000mgll 20C 2 1 20ml 40ml 2 2 ODS 6 10ml 20ml 3 i 7 4 a 0 25mm 30m 0 Sum 8 9
52. i gt L 2 1 9 5 1 9 21 9 1 5 En 2 14 8 15 56 2 19 21 9 15 2 14 8 15 56 2
53. 16 ug hg ug 16 20 5 dk 1 5 ng 1 2
54. 2 1 17 18 3 0 05 5 ug 1l d 3 0 5 ug1 17 19 4 a 20C 40 b 20 20 c
55. H16 Hi6 H16 Hi6 H16 H16 H16 H16 Hi9 0 1 _ 006 016 9 3 10 2 1 1 2 1 4 3 3 10 1
56. 5 ug ml 5ml 0 100ml 9 5 4 1 ng ml 5ml 2 4 6 4
57. 5mg 1 50kg 10 1 12 WHO 1999 IPCS Environmental Health Criteria No 215 Vinyl Chloride World Health Organization Geneva Switzerland Gangolli S 1999 The Dictionary of Substances and their Effects 2nd ed The Royal Society of Chemistry Cambrige NITE amp CERI 2005a GDCh BUA German Chemical Society Advisory Committee on Existing Chemicals of EnvironmentalRelevance 1989 Viny Chloride Chloroethene BUA Report No 35 S Hirzel Verlag Stuttgart NITE amp CERI 2005a 1997 1997 12 26 NITE amp CERI 2005a NITE amp CERI 2005a Freitag D Ballhorn L Geyer H and Korte F 1985 Environmental hazard profile of organic chemicals Chemosphere 14 1589 161
58. 6 NITE amp CERI 2005a 15509 WHO 2 2 Guidelines for drinking water quality 2 9 ed Vol 2 Health criteria and other supporting information World Health Organization 1996 WHO 3 Guidelines for drinking water quality 3 9 ed Vol 1 Recommendations World Health Organization 2004 19 PRTR 21 tt CD Ma Feron VJ Hendriksen CFM Speek AJ Til HP amp Spit BJ 1981 Lifespan oral toxicity study of vinyl chloride in rats Food Cosmet Toxicol 19 317 333 U S NLM U S National Library of Medicine 2001 HSDB Hazardous Substances Data Bank Bethesda MD NITE amp CERI 2005c 13 1976 1976 5 28 NITE amp CERI 2005c
59. 73 0 0002 5 9 0 0002 0 0002 40 0 002 268 0 0002 6 2 0 00001 8 21 OB2 TIDBO061 0 0002 0 00001 43 1 4 1 5 0 6 0 lt 16 9 2 5 5 9 en 02 0 gloo 0 0002 0 003 0 001 0 20 72 0 0000 0 002 0 00005 0 0002 8 6 0 1 73 0 SN 76 0 a i 0 04 2159 0 WHO 2030 0 465 1 979 0 18 891 8 1 2 004 17 911 0 08 0 282 2320 A 8 3 _ 5 1 288 2 123 0 MR 230 isolo 43 0 204 1 631 WHO 20
60. Technology and Evaluation CERI Chemicals Evaluation and Research Institute x FF 1 1 K0557 A 4 A 3 1 2 KK8891 2 3 99 4 100 pg ml 65 ml 50 ml 3 000 pg 3 4 5 1 pg ml 50 90 ml 100 ml 1 ml 100 ml 6 100 pg ml 65 ml
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