- 1 - 平成25年7月24日判決言渡 平成24年（行ケ）第10207
Contents
1. 4 5 3 1 0 5 32. HPLC 1 0
3. 7 3 2 CHIRALPAK 38 AD n 2 n 0 1 0 1
4. 26 1 2 0 3 9 7 3 a 1 0 1 0 No 6 2 1 S
5. 50 28 1 1 6 3 4 2 1 0 NO 2 2 6 1 1 1
6. HPLC NL 36 3 7 7 9 3 1 HPLC
7. 1 3 5 3 5 0 8 1 2 26
8. S Blaschke
9. 8 1 2 31 2 6 5 8 1 2 2 6
10. 3 R S 1 S 3 5 3 1 3 1
11. A 2 46 4 2 1 4 2 2
12. 2 2 1 75 1 3 7 6 1 7 20 3 77 1 9 20 S 5 3 HPLC 2
13. HPLC CHIRALCE L OD CHIRALPAK AD 7 1 2 5 1 4 9 5 3 5 1 9 9 6 Tetrahedron Asymmetry 3 4 9 HPLC 36 NMR 32 GC 2 2 1 19 HPL C 5 6 7 1 3 1 6 1 2 9 3 1 7 1
14. 3 1 0 1 3 8 3 R S 3 7 7 8 78 R S 1 S
15. 5 1 1 1 6 7 2 6 7 3 1 1 1
16. CHIRALPAK AD 7 3 2 3 4 HPLC CHIRALCEL OD CHIRALPAK AD
17. 2 3 5 27 b 2
18. S R 5 0
19. 3 7 7 2 1 5 5 3 HPL C 7 5 1 7 HPLC HPLC 7 HPLC
20. 7 1 7 6 S 1 6 7 2
21. 6 7 3 20 6 7 3 1 1 S 10 S
22. A 3 S 1 S 2 4 2 6 2 8 HPLC C HIRALCEL OD CHIRALPAK AD 7
23. S 1 0040 004 8
24. 1 S 1 2 2 34 1 5 3 5 3
25. 6 7 6 7 1
26. CHIRALCEL OD CHIRALPAK AD 7 44 1 CHIRALCEL OD CHIRALPAK AD 2 5
27. 3 7 32 7 2 5 3 5 7 1 7 7
28. CHIRALPAK AD n 2 lt 7 3 2 3
29. S R S S S R S R 2 7 1 R S R 2 2 R
30. 1 2 1 3 3 2 1 2 29 b 1 2 1 3 8 7 1 0 5 7 5 1 7 5 1 1
31. 2 7 5 60 94962 61 19406 8 2 3 2 zr 2 4 1 3 a
32. 7 6 7 3
33. 1 7 3 2 3 7 3 2 5
34. 4 3 1 HPLC 35 V 9
35. 0001 f 2 25465 TL 14 4 Tn 0 O A gt 1 000 2
36. homologousPCA S R 1 1 00 36 S I S S 0048 S I 9 S R 8 3
37. S 5 1 1 1 9 S 4 4 4 0 2
38. 4 4 4 2 4 4 4 2 1 S 1 S 4 4 4 2 3 1 2 1 1 1
39. 2 3 R S 3
40. S R 2 S 48 1 7 S S R R S R
41. 8 1 2 2 6 2 HPLC 0 1 37 7 3 2 7 3 2 7 3 1 7 3 2 7 9 8 2 CHIRALPAK AD
42. A 2 6 I I1 Ar Ar b 5 1 1 2 22 1 7 2 B
43. 3 3 3 I S 1 2 1 2 1 1 2 1 2 1 DL 1 1 1
44. 7 3 2 2 n 2 80 20 v v 3 nm 2 1 0 0 0 0 0 0 v v 190 0 85 15 50 50 0 100 v v 100 0 85 15 35 65 0 100 v v 40 2 0 1 v v Max 1 0 0 1 v v Max 0 5
45. 0 9 6 4 1 0 0 9 7 40 6
46. 1 S 1 1 S 1 1 S 1
47. S 2 4 1 1 1 1 1 1 S 1 1 S 1 2 1 7 15 4 1 S 1 S
48. 2 7 7 7 7 2 5 3 5 7 1 7 3 S 1 S
49. 0006 a S R Ke S S 4 2 3 RJ RJ 4 4 2 4 1 4h 5ml kg 2 1 25 mg kg
50. 3 S 49 4 S 1 2 1 S R 71 S R
51. 6 3 1 2 3 2 5 7 1 5 4 1 CHIRALCE L OD CHIRALPAK AD 6 4 E CHIRAL PAK AD 6 3 Type IL
52. S R 4 3 homologous P C A S R 100 0 030 0 0 35 S R S 0048 8 3 3 S 7 4 S 3
53. CHIRALPAK AD n 2 0 1 PLC 0 1 39
54. 8 3 S 7 2 2 S R 2 R R
55. 4 93 2 2 7 8 6 313 493 0 63 Q 5 3 7 2 1 0 8 9 43 8 2 3 5 4 9 3 1 8 5 7 8 1 2 8 3 9 1 7 9 478 11 3 5 8 480
56. 1 1 1 DL 4 1 a b 19 I S 0036 0039 S 4 4 4 2 1 2 S 4 4 4 2 5 0 0m
57. 40C 75 1 R 4 4 3 S zz 1 1 1 96 9 96 9 96 96 2 2 65 0 15 0 16 1 20 1 20 0 87 1 15 0 37 0 39 0 37 0 49 0 45 0 18 0 05 4 S R 20 R
58. 5 3 5 3 5 3 7 7 1 0 5 2 5 5 7 5 1 7 5 1 HH PL C 7 6 HPLC 0 1 7 CHIRALPAK AD 73
59. 1 Ar 9 r Ar Ar A 2 6 B 2 1 6 3 7 b 4 4 4 2 23 1 3 1 0
60. HPLC 2 HPLC 0 1 1 5 0 9 6 4
61. 1 1 S 33 7 1 3 6 6 1
62. 6 3 CHIRALCEL OD CHIRALPAK AD 45 6 3 6 3 CSP CSP CSP 4 6 1 0 1 CHIRA LCEL OD CHIRALPAK AD Type IL
63. 5 0 0 CHIRALCEL O D CHIRALPAK AD C HIRALCEL OD CHIRALPAK AD 5 0 0 CH IRALCEL OD CHIRALPAK AD CHIRALCEL OD CHIRALPAK AD Type
64. 1 16 1 1 mg kg p o hn 9 0 01 8 0 0 02 7 42 9 S 0 03 8 62 5 0 06 8 100 0 1 8 100 0 3 8 0 0 6 8 0 R 1 0 8 50 0 3 0 8 62 5 10 0 8 100 np 7 homo1ogousP CA PCA 2 3 2 5ml BPO BGG IgE 0 0 ye 7 benzylpenicilloyl bovine serum albumin BB PO BSA 500gmg 1 Evans Blue 1m PCA 3 0 1 6 h 2 2 17 2
65. 5 1 2 51 3 6 ul 3 52
66. 50 1 0 7 2 1 3 S S 1 S
67. 1 3 6 1 2 1 2 1 S
68. 12 19 8 1 2 2 6 9 35078 4 0 1 2 2 1 0 2 1 9 1 4 2007 1 000 32961 0 9 2 3 3 1 8 3 9 2 3 6 9 098 1 3 2011 800 2 4 4 2 3 5 9 2 9 1
69. S CHIRALPA K AD CHIRALCEL OD 7 3 1 5 5 5 5 5 3 2 5 25 6 2 2 5 5 0 0 CHIRALCEL OD CHIRALPAK AD CHIRALCEL OD C HIRALPAK AD
70. 1 1 1 S 1 2 HPLC No 6
71. D R R S 1 2
72. 2 0 86g 9 2 3 a 4 4 2 4 98g 16 45 4 3 85g 19 74 3 5m 1 2 73g 19 75 4 4 4 4 2 1 6 26g 91 4 3 4 4 4 2 1 2 4 4 4 2 25 NMR_ CDC 1 3 6 ppm 1 84 1 98 6H b m 2 58 2H
73. 1 c I Ar Ar 4 1 3 1 6 d 1 2 p 4
74. Typ e IL 2 6 3 6 3 CHIRALCEL OD CHIRALPA K AD 2 13 4
75. 3 5 35 35 34 34 35 8 0 570 4 2 5 b 5 3 2 5 2 5 2 5 6 2 4 4 3 5 3 5 2
76. HPLC CHIRALCEL OD CHIRALPAK AD 12 5 6 CHIRALCEL OD CHIRALPAK AD
77. 0030 0035 S 4 S I S S O I S 1 I S X gt D gt
78. 2 7 homelogousP CA ng kg p o n 9 0 01 10 37 3 0 02 8 46 3 S 0 03 9 56 9 0 06 8 63 4 0 1 8 58 8 0 3 8 3 1 Ne 1 0 8 13 6 Ne 2 3 0 8 45 8 10 0 8 59 5 8 5 b 1 S R S R ED 0 0 2 3mg kg 1 0mg kg S R 4 3 2 P CA S R 7 0 50 3 5 S R 1 0 0 S R
79. 1 0 0 30 4 375 1 20 75 1 8 1 2 26
80. 2 5 7 2 4 2 4 10207 2 5 6 1 2 ss lil 2 1 4 704362 9 Nil 2011 800098 2 4 4 2 3
81. homol1ogous PCA S R S S 7 21 2 1 1 1 1 1 a Ar 9 Xcar o A C Ar
82. 2 2 i S 2 2 2 50 R 6 ES 1 1
83. 6 HPLC 5 3 7 1 0 5 75 1 7 5 1 HPLC 1 0 1 0 0 3 7 5 13 20
84. 1 2 3 1 I 1 Cl O NOINSS 1 S 2 I 1 3 ul k NN k 3 S 1 I S 1 1 1 4 2 2 25465 63 175 1 7 2
85. 2 19 CHIRALPAK AD 7 3 1 3 95 7 9 1996 8 2 2 3 3 HPLC CHIRALCEL OD CHIRALPAK AD 4
86. 1 c 5 25 5 34 2 5 CH 1 5 35 2 5 CH I RALPAK AD a b 1 CHIRALCEL OD 1 RALCEL OD CHIRALPAK AD 50 0 8 0 7 HPLC
87. 1 5 41 1 B 1 47 1 S 1 S S 1 1 S 5 9
88. 4 2 6 1 1 1 1 1 2 9 1 3 2 2 1 3 1 2 3 29 1 3 2 2 1 1 1 4 4 4 2 1
89. 5 3 1 6 e C 4 4 4 2 4 1 6 7 8 f 7 1 C 1mg kg 24 1 0 0 2 1 3 4 4 2 1 1 00 g 2 48 5 0 1 m 1 8 m 1 2 3 4 4
90. 4 5 6 5 6 3 1 6 2 1 19 9 6 8 HPLC a 7 3 1 5 5 5 42 3 5 34 6 0
91. t 2 73 4H b m 2 92 2H 6 3 68 1H m 7 17 7 22 7H m 8 51 1H m 11 31 1H b 8 20 9 15 1 g 4 1 e fF 3 6 2 10 1 Vo1 29 No 1 0 3
92. 1 HPLC CHIRALCE L OD CHTIRALPAK AD 3 0 1 2 S 1 S 1
93. lt 0004 25 4 311 336 1989 0005 zx 1 S 4 4 4 90 15 2
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