クォンティフェロン TB-2Gの使用指針
Contents
1. 4 2 QFT QFT QFT 4 32. FN IFNs FNc IENs 0 35 IU mL FN IFNN 0 5 IU mL 4 0 7IUmL 350
3. QFT 12 3 QFT 3 1 Gold standard IFNE IFNJ FNc IFN 0 35 IU mL A Bn 0 1 IU mL 0 35 IU mL 0 1 IU mL FN IEN FN IFN 0 35 IU mL
4. PPD BCG BCG BCG PPD BCG BCG PPD QFT ESAT 6 1995 CFP 10 1998 T
5. QFT 45 5 7 1 33 0 7 45 mm BCG 4 5 QFT 0 87 8S5 0 87 BCG QFT
6. 10 mm 5 mm OFT 8 10 QFT 8 396 QFT 8 QFT
7. 2005 12 15 Brock I Weldingh K Lillebaek T et al Comparison of tuberculin skin test and new specific blood test in tubercu losis contacts Am J Respir Crit Care Med 2004 170 65 69 Harada N Nakajima Y Higuchi K et al Screening for tuberculosis infection using whole blood interferon y and Mantoux testing among Japanese healthcare workers Infect Control Hosp Epidemiol In press 2002 2003 52 1260 1266 OuantFERON Gold 2005 80 527 534 2004 79 197
8. 5 mL 1 mL 4 ESAT 6 CFP 10 PHA 12 37 12 20 18 50zL ELISA HRP TEN y 120 22 5C 100 gL 30 30zL 5 450nm 620 nm 650 nm
9. QFT 29 3 2 Mori QFT 216 20 93 1 BCG QFT 1 9 95 0 5 4 7 QFT 98 20 1 89 QFT 99 BCG 573 QFT 99 8 99 1 QFT
10. TNF z 50 QFT 7 QFT QFT QFT X QFT QFT MAC
11. QFT 12 QFT 1 Andersen P Andersen AB Sorensen AL et al Recall of long lived immunity to Mycobacterium tuberculosis infection in mice J Immunol 1995 154 3359 3372 Berthet FX Rasmussen PB Rosenkrands I et al A Myco bacterium tuberculosis operon encoding ESAT 6 and a 2 novel low molecular mass culture filtrate protein CFP 10 Microbiology 1998 144 Pt 11 3195 3023 ESAT 6 CFP 10 QuaniFERON TB 2G 2004 79 725 733 Mazurek GH LoBue P Iademarco MF et al Guidelines for using the QuantiFERON TB Gold Test for detecting Mycobacterium tuberculosis infection United States MMWR 2005 54 RR1S 49 55 Mori T Sakatani M Yamagishi F et al Specifc Detection 3 4 3 of Tuberculosis Infection with an Interferon gamma Based Assay Using New
12. IFN y FN IFNN IFNc IFNs IFN IFNs 3 IFN gt ESAT 6 CFP 10 0 35 IU mL 0 10 IU mL 81 2006 3 0 35 IU mL
13. 2 394 Cellestis IFN y IFN gt 30 2 1 1 4 IFN y ESAT 6 CFP 10 IFNs IFN FNNJ QFT Nw
14. gt IFN y QFT ESAT 6 7 CFP 10 6 IFN gt ELISA Mycobacterium tuberculosis M bovis M africanum M kansasii M marinum M szulgai M flavescens M gastri 47 epzyge M bovis BCG M avium M intracellulare QFT 1 IFN y 2 IFN gt ELISA 2
15. FNw IFNN 0 5 IU mL QFT 5 HIV TNF TB 2G Mori 1 119 13 86 54 66 QFT 89 0 95 81 9 94 0 CDC QFT 23 91 95 73 9
16. 100 4 5 4 1 QFT 10 mm 5 mm 20mm 10 mm QFT QFT
17. QFT 81 2006 3 5 QFT QFT QFT QFT ESAT 6 CFP 10 QFT
18. Antigens Am J Respir Crit Care Med 2004 170 59 64 Mazurek GH y 16 2003 3 Brock I Munk ME Kok Jensen A et al Performance of whole blood IFN gamma test for tuberculosis diagnosis based on PPD or the specific antigens ESAT 6 and CEP 10 Int J Tuberc Lung Dis 2001 5 462 467 6 7 TB 2G 8 10 11 Ravn P Munk ME Andersen AB et al Prospective evaluation of a whole blood test using Mycobacterium tuberculosis specific antigens ESAT 6 and CFP 10 for diagnosis of active tuberculosis Chn Diagn Lab Immunol 2005 12 491 496 Kang YA Lee HW Yoon HI et al Discrepancy between the tuberculin skin test and the whole blood interferon gamma assay for the diagnosis of latent tuberculosis infec tion in an intermediate tuberculosis burden country JAMA 2005 293 2756 2761 QuaniFERON TB 2G 2004 79 637 643 QuantiiFERON TB 2G 12 13 14 15 16 17 397
19. 8 79 QFT 1 18 72 95 49 88 7 48 85 95 75 96 92 12713 QFT 54 81 95 69 90 78 QFT 80 90 QFT
20. Kekkaku Vol 81 No 5 393 397 2006 393 TB 2G 18 5 BCG TB 2G Cellestis QFT 2005 4 2006 1 BCG Re 1 QFT
Download Pdf Manuals
Related Search