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1. lt Ava o e as Men ne e 8 ADME
2. 1020994060 03 6859 9700 QJPN Corpmktg quintiles com O OUINTILES www quintlles coJp email quintiles com Copyright 2014 Quintiles All rights reserved 02 0012 1 01 15
3. e e BD e es E e aye es e 1 2 3 4 5 6 7 SIV es e s e BE QCC A IITAII A AU UO 1 ee e 144 e
4. 40 50 199 244 14 483 ZIJV ZVIR 1 501 ARAFE hE RARE HAKI fA EFIKAS Q QUINTILES Improve your probability of success Methodology Example biomarker assays Automated chemistry urinalysis Hematology coagulation Flow cytometry Anatomic and molecular pathology Microbiology Genomics Mass spectrometry Immunoassay Enzymatic analysis Colorimetry Turbidimetry Spectrophotometry Automated cell counting Leukocyte differential counting Conductivity and light scatter Chromatography Clotting time Light scatter Cellular fluorescence Custom panel development Tissue processing FFPE cryo TMAS H amp E Digital pathology Assay and algorithm development IG Shi Fist Mutation and expression analysis PCR RT qPCR Direct inoculation Molecular characterization PCR and variants SNP Analysis Universal array sorting FISH NextGen sequencing LC MS MS Standard plate ELISA Multiplexing Immunoblotting
5. e Quintiles Infosario Site Gateway 21 CFR Part 11 ADE QLU D Bee 250 wat ia DOD Zor IES CAP
6. RIBA Automated immunoassay platforms Routine chemistry Urinalysis Endocrinology Tumor markers thyroid functions CBC WBC differential Reticulocytes HbA1c Prothrombin time aPTT Fibrinogen D dimer proteins S amp C Von Willebrand factor T cell subsets Minimal residual disease Phosphomarkers Activated T and B cells NK cells Dendritic cells Monocytes Activated granulocytes PISK EGFR RTK pathways Apoptosis cell death markers MAPK pathway Tumor stroma and infiltrating lymphocytes Companion diagnostic CDx assays Bacteria and yeast identification Antimicrobial susceptibility Ova and parasites TB testing Latent TB infection Viral loads and genotyping ADME PGx HLA typing GEP array RNAseq Whole or targeted exome sequencing Drugs of abuse Hormones Metabolomics Immunogenecity ADAs HAHA Cytokines Immunoglobulins Cardiac and bone markers RFP FPFV RFP e e es e
7. At a glance FAURE MV QLAB ADME 2013 35 30
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