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24時間血圧計の使用（ABPM）基準に関する ガイドライン

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1. OOO 0000000 60 ABPM 000000 000000000000 2000000000002000000000000 00000 000072220 200000 000000000000000000 0000000 0000 0000 000000000000000000 000000000000000000000 000000000000000000000 00000000000000000000 5 950000000000 0 8 00000000 00000000000000000000000 00 00000000000000000000 0000000 000000 000000 00000000000001 0 000 amplitude 000002000000 0000000000 200000000000000 Oooo oOo 24000000000 000000 0000000000000002000000000 000000000000000000000000 00000000000000000000000 00000000000 tilting table 0 0 00000 0 0000000000000 0 00000000000000000000 0 00000000000000000000 0 00000000000000
2. Accuracy SBP DBP BHS Criteria Author A amp D T2420 kM 12 2 5 BJ B Tochikubo et al 55 KM 1 8 35 etal 56 2421 05 B A etal 57 2425 KM 2 2 1 0 B A Tochikubo et al 58 Colin ABP630 KM 1 3 C B White etal 59 Der Mar Avionics KM 3 C D O Brien etal 60 Pressurometer IV Spacelabs 90207 KM 3 B O Brien etal 61 Suntech Accutraker KM 13 4 5 A C Taylor et al 62 Terumo ES H531 KM 0 9 0 1 etal 63 05 2 B Sun 29 I 0000 000000 SBP DBP mmHg 000000000000885000000 0 000000000000000000000 0 000000000000000000000 000000000002 00000000000 000000000000 300000000000 0 000000000000000000000 0000000000000000000000 0 000000000000000000000 50 0000 3000000000 80800000000 00000000000 ABPMOOOOOO 0000000000000000000000 000000000000000002 000 0000000000000000000000 0 000000000000000000000 85000000000000000000000 0 000000000 0000002000000000000000000 000000000000 00 scatter 2 00000000 Bland and Altman plotting 0 020020000000 00 000000000000000 ses 000 _________ mmHg 00 BHS 00 5 mm 00 0 800 0 19900 0 0 0 00000
3. 0 000000000000000001998 1990000000000 0000000200000000000000000 0000 0000000000 Oooo oo 00 00000000000000 2 jon 0000000000000000000000000 A amp D y i 2 0000000000000 2421 24250 05 037 0 19600 700 00 00000 00000 0000000 630 KM OS 082 019900000000000000000000000 AA 200 00000000000 070 Del Mar 1990P IV KM 0 82 Avionics 1 ABPM Instromedix BA RO G 224 KM 0 34 00000 FB 240 0 5 KM 0 37 Oxford Medikog ABP KM 0 57 P 1 1 Sensormedix Diasys 200 KM Wis 000000000000000000000000 00000 05 240 KM OS 0 45 0000000000002000000000000 Space labs 90202 os p 0000000000000 mm0 0200 00 mile Suntech Accutracker KM 0 36 0000000000000000000000000 e AS SAS 0000000000000000000000000 o000 pois ines AUS se 0000000000000000000000000 0000000000000 000000000000 0000 oo 1600000000040000000000720 100000000000000000000000 mulli biomediealirecorden 0000000000000000000000000 00000000000000000920 19590 0000000000000000000000000 Smirk 00000000000000000000 0000000000000 00
4. 00 00000 stae 300000000000000 0 00000000000000000000 000000 00000000000000000000000 0000000 7000000000000000 00000000000000 350 470 1360 000 0028 020 00000000000000070 900000 0 0 0 0 0 0 0 2 Oooo OO 00000000000000000000000 0000000000000000072 200000 000 8 0000000000000 0 0000000000 000000000000000000000 0 0000000000000000 40000 0 000000000000000000000 Japanese Circulation Journal Vol 64 Suppl 2000 1215 0000000000000000000 00 1998 19990 000000000 0000000000000000000000000 0000000000000 O000000000000000000000000 0000000002400 ABPM 00000000 0000000000000000020000000 O000000000000000000000000 000000002400 0000000000000000000000000 O000000000000000000000000 0000000000000000000000000 8 0000000 oooooooooooooooooooono 0000000000 0 FR oon 00
5. gt non dipper 0 0000 3 V OO 0 0000000000 0 0000000000 000 00000000 0002400000000000000000000 000000000000000000000000 000000000000000000000000 00000002400000000000000000 000000000000000000000000 000000000000000000000000 000000000000000000000000 00002400000000000000 10 evidence based 20 practical 0O 00000000000000 0000000000200000000000000 00000000000000000000000 000000000000000000000000 00240000000000000000000000 000000000000000000000000 0000040000000000000000000 000000000000000000000000 000000000000000000000000 000000000000000000 00000000 0000 00 H AAMIQ SPIOQ OOO 00000000000 000000 20000 0000 0 00000000000 0000000 20 00000150300000000001000 000000000000024000000000 00000 30 000000000000000000000 00000000000000000000 40 0 000000000000000 0 000000000000000000000 000 000000000000000000000000 00000 mmHgs SBP 00 0 0 0 02 250 mmHg 70 1 mmHgs DBP 0 0 0 0 Os 130 mmHg 30 20 2400000000
6. 4 O 1 0 0 0 0 0 Oooo 0 0 0 0 0 0 oOo 55 0 0000000 30 ml min 000000000 non dipper 0 0000000 0000000000 00 non dipper 0000 000000000 dipper 00000000 0 00000000000000 non dipper 0 0000 Portaluppi O0 000000000000 00 000000000000000000000000 00000000000000000000070 0 000000000000 Og 00000000000000000000000 00000000000000720000000 00000000000000000070 0 0 0 0 0 0 0 0 0 w os 2 2 O oO 0 0 0 0 0 0 0 0 Oooo o 1 Oooo oo a ooo Japanese Circulation Journal Vol 64 Suppl 2000 1219 000000000000000000000 1998 19990 0 00 0 00000 00000000000000000000 non dipper 0 0 4 0000000000000000 000000000000000000000 00000000 0 00000000000001 0000 0 00000090 8600000000000 0000000 000000 ABPM 00000000000000000000000 00000 7000 ABPMQ OOO 0 00000000000000000000 00000000000000
7. 8 000 00000000000020 0000000000 DO00002000000200000000000 000000000000000000000000 000000000000000 0000000000000000000000000 0000000000000000000000000 D D D cosine fitting 00000000000000 00000000024000000000203600 00000000000000 amplitude acrophase0 O000000000000000000000000 00000 0000000000000000000 00000000000000000000000100 00000000 0 00000000000 O0000000000000000000000000 zero amplitude test 0 0000000000000000 0000000000000000000000000 000000000 percent rhythm 0 00000 000000000000 0000000000000 2080000000 pue DDDUUDDDDDDDDUUDDDDDDDUDU 0000000000000000000 singe cosas 0000000000000000000000 02 0 000000000000000000 ampitude0 O000000000000000000000000 acrophase 00000000000000000090 O0000000000000000000000 0000000000000000000000000 000 rroooooooooooooooooooo 9 00000000 000000000 cosine fitting 00 0000 0000 000000000000000000000000 0000000000000000000000000 8 cosine fitting 000000 000000000000000000000 000000000 amplitude 000 000000 ________ 000000000000000000
8. Bo Eil Oooo o gt ry lt 000 000 000 000 000 000 9 OOO 1 oo lt G A EGO G O O ooo OOo Ooo oo 3 Ooo 1230 Japanese Circulation Journal Vol 64 Suppl 2000 000000000000000000001998 190000000000 000000000000000000 n 00000000000007 0 0 5 0 0 0 0 ooo ooo 00000000000 0 00000000000 00 000000000000 0 0000000000000000000 0000000001 30000000000000 0000000070 00000006 000 0000000 0000 nifedipine 0 000000000000000 00000000000000 00000000000000 00000000000000000 00000 amlodipine 00000000 000 010000200000 0000 0000 0000000000 0 000000000000000000 0 00000000000000 0000000000000000020 ACE
9. 0 0 0 0 0 0 0000 short window 000000000000000000 90000000000 00000050 0 00000000000000 0 J MUBA 5000 00000000000000 short window 0 00000000000000200000 0000000 0 0 0 0 0 000 000000 2400 000000 000000 Be 1 1 1 00 000000000 00 2400 0 0000000 000000 000000 00000 24 0 0000000000000 0000000000000 000000000000 00000600 000000000000000000000 000000000000000000000 000000000000000 00000000000000000000 0000 00000000000 000000 cut off point 000000000 00000000000150000000 0 00000000000000000 120000000 160 and or 95 mmHg OOO 0 00000000000000000 000000000000000000 90 000002800000000000 0 00000000 0000000000 00000000 000000000000000600000 000000000000000000000 ooo FO OOO 0
10. 2550 Hermida RC Ayala DE Diagnosing gestational hypertension and preeclampsia with the 24 hour mean of blood pressure Hypertension 30 1531 1537 1997 2560 Halligan A O Brien E O Malley K et al Clinical application of ambulatory blood pressure measurement in pregnancy J Hypertens Suppl 9 575 77 1991 00000 2570 Dupont AG Van Der Niepen Six RO Placebo does not lower ambulatory blood pressure Br J Clin Pharmacol 24 106 109 1987 2580 Conway J Johnston J Coats A et al The use of ambulatory blood pressure monitoring to improve the accuracy and reduce the number of subjects in clinical trials of antihypertensive agents J Hypertens 6 111 116 1998 259 Mancia G Omboni S Parati G et al Lack of placebo effect on ambulatory blood pressure Am J Hypertens 8 311 315 1995 260 Coca A The placebo effect in ambulatory blood pressure monitoring Blood Press Monit 3 195 199 1998 2610 Staessen JA Thijs Bieniazewski L et al Ambulatory monitoring uncorrected for placebo overestimates long term antihypertensive action Hypertension 27 414 420 1996 262 Antivalle Lattuada S Salvaggio et al Placebo effect and adaptation to noninvasive monitoring of BP J Hum Hypertens 4 633 637 1990 2630 Mengden Weisser Vetter Ambulatory 24 hour blood pressure versus self measured blood pressure in pharmacologic trials J Cardiovasc Pharmacol 24 Suppl 2 S
11. 000000000 000000000000000000000 0 00000000000000000000 0 00000000000000000000 000000000 morning surge 000000000 trough peak T P 00000000000000000000000 00000000000000 trough peak 0 TP 0 000000000000000000000 00000000000000000 0020000 0 0 ooo 00000000000 5 mmHgQOOOOOOOO 2800000000000 0270000 000000000000 trough 0 0000000000 000000000 000000240000000000000000 00 0 00 00000000000000000000 00000000000000000 0 tough 00000000000000000000 c smoothness index Oooo Oooo Coy 11 Ooo Oooo 0000000000000000000 0000000000200000000000000 00000 smoothness inde 500 0000000 7220 510 1000000000 2400 000000000 00 00000000000000000000 00000000000000000000 0 5100000000000000200 00000000000000000000 hyperbaric index hyperbaric index 000 hyperbaric areal QO O00 00000000000000079270 0000024 0000000000000000000000 mmHex hr 0 0 0 0 0 0 hyperbaric index 100 0 0 0 0 O B
12. D white coat effect 00007000 0 0 000 0 0 0 0 0 0 0 Oooo oOo 0000 0000 0000 3 FH TY ooo Ooo Oooo oo oOo OOOH 1 1 1 oo oo a oOo oOo oo JT 1 0O Oo OO Oooo OO Oooo oO oO Oooo OO Oooo oO oO gt lt 4 OO OA OO Ga 4 DT 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Oooo Oooo O O O an G0 OC O oo mm q 3 1
13. 00000000000000000 0 000000000000 10100000 0 0 0000000 20 000000 0 00000000000000000000 80010 8 0000000000 400000000000 0 00000000000000000000 000000 20000000000 0 00000000000000000000 0000000 0 0 0 0 0 0000 0 0 0 0 0 0 Oooo 0 0 0 0 0 0 1 0 0 0 0 0 0 0 E G 1 OOO a oo G G 3 34 1 0O GO 3 000 000000000000000000000 000000000000000000000000 0000000000000000 indapamide 000 000000000000000000000000 009000000070 0000000000000 losartan candesartan 00010 10000000000000000000 0 000000000020000000000000 00000020 PPA 0000000000000000 00000 0000 000000000000000 000000000000000000000000 0000000000000 080000000000 000000000000000000000 000000000000000000000 000000000000000000000 0000 0000000000000 00000000000002400000000 0000000
14. 240 00000000 00 00 00000600 00000 800 100000 060000000000 000000000000000000000 800000000000000000000000 Schillaci 400 000000000000000 0 0000000000000000000 600 000000000 00000 000000000000000000000 0 00000000000000000000 0 000000000000000000000 0 000000000000000000000 0 000000000000000000000 0000000000000000000 0000000 plasma volume 0000000000 0 000000000000000000000 000000000000000000000 0 00000000000000000000 00000000000000272000 6 9000 0000000 ADP epinephrine 0000000 100000000000000000000000 0 00000000000000000000 0 0 0000000000000000 000000000000 000000000000 00000000000000 Moore DO adrenaline 000000000000000000 0000000000000 240000000000 0 00000000000000000000 0 000000000000000000000 000000 morning surge 000000000000 0 00000000 5 a a n a 3 3 1 ey 3 oOo Oooo OO Ooo ae 0 eo 3 EB
15. o 1 OOOO O z o ae 120 GOG G oo oOo 1 Cl GO OOO OOOO OOOO OG 0 198 200 bo T 3 ET J J J ooo 4 O00 O00 00 OO Og 2 23 01 01 0 0 0 0 0 0 0 0 0 0 0 0 0 0 OOOO OOO ga n 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GO peep OOOO OOO OOOO OOO OOOO OOOO OOO OOOO OOOO OOO OOOO OOOO 0 2 OOOO p 28 00000 4000000000000000000 20000000000000002000 00000000000000000 fitting 0 O single cosinor 0 0000000 00000000000000000 0 000002022 000000000000000000 00000000 300000000 MESorg amplitude acrophae 000000000000 3000000000000000000000000 0000000
16. Japanese Circulation Journal Vol 640 Suppl 2000 1229 000000000000000000000000 00 00000000000000000000 140 90 000000000000000000 00000000000000000 000000 000000000000000 0 000000000000000000000 000000 cumulative sum cusums 0000000 0 00000000000000000000000 00 0 0000000 000000000 000000000000000000 0000000000000000000 0000 000000000000000000 72290 0 00000000000000000 0 0000000000000000 0 00000000000200000000 00000000 OOOO 000000000007 0 000000000000002000 0 00000000 00000 0000000000 000000 419 0000000 95 mmHg 00 0 000000000 mmHg 0000000000 0 80 89 00 0000000000 mHgQOOOO0000000000000 60 000000000000 0 00000000000000000 004000000000000000 0 000000000 000000 000000000000000000 ABP 0 0000000000000 8 0 0000000000000000 0 00000000000000000 0 0000000000000000 oOo oOo oOo 0 0 0 A oOo ooo
17. cardiovascular load in high altitude workers Arch Mal Coeur Vaiss 84 1143 1148 1991 1147 Gretler D Carlson G Montano A et al Diurnal blood pressure variability and physical activity measured electronically and by diary Am J Hypertens 6 127 133 1993 24000000000 115 Staessen Bieniaszewski L O Brien et al Nocturnal blood pressure fall on ambulatory monitoring in a large international database Hypertension 29 30 39 1997 116 Palatini Mormino Canali et al Factors affecting ambulatory blood pressure reproducibility results of the HARVEST trial Hypertension 23 211 216 1994 117 Kobrin Oigman W Kumar A et al Diurnal variation of blood pressure in elderly patients with essential hypertension J Am Geriatr Soc 32 896 899 1984 118 O Brien E Sheridan J O Malley K Dippers and non dippers Lancet 13 397 1988 119 Shimada K Kawamoto A Matsubayashi K et al Diurnal blood pressure variations and silent cerebrovascular damage in elderly patients with hypertension J Hypertens 10 875 878 1992 120 Bianchi 5 Bigazzi R Baldari et al Diurnal variations of blood pressure and microalbuminuria in essential hypertension Am J Hypertens 7 23 29 1994 121 Verdecchia Schillaci Boldrini F et al Sex cardiac hypertrophy and diurnal blood pressure variations in essential hypertension J Hypertens 10 683 692 1992 122 Nakano
18. 0 00000000000 cathecolamine QQ 0 00 00000000000000000000000 0000000000000000000 norepinephrine 0000000000000 00000790 00000000000 0000000000 00000000000 0000000000700000000000 00000 00 000 000000 00 000 0000000000000000 000000000000000000000 0000000000000000 0 0 0000000000000000000000 000000000000000000000 Cushing 000 Cushing O 0 O Cushing 000 00000 corticoid 0O00 000000000000 000000000000 Cushings 00000000 Addison 0 0 00 0000000000000000 geg bl 00 corticoid 000000 Oooo Oooo 0000 aldosterone 00000000000000 0000 aldosterone 000 00 alkalosis 0 00000000000000 aldosterone 000 0000000000000000000000 0 0000000000 00000000000 000000000000000000000 aldosterone 00000000000000000 0000000000000000000000 0000000000000000000000 0000000000000000000000 00000 aldosterone 00000000000000 000000000000000000790 700000000 00000000000000000000000 0 00000000000000000000 0 00000000000000000000 00000020 OO00000000000000 00000000000000000000000 1225 Japanese Circulation Journal Vol 64 Suppl 2000 000000000 rening 0000000 00000000000000000000 OOOO 000000000000
19. 410 The Joint National Committee on Prevention Detection Evaluation and Treatment of High Blood Pressure The Sixth Report of the Joint National Committee on Prevention Detection Evaluation and Treatment of High Blood Pressure Arch Intern Med 24 2413 2446 1997 42 Guideline Subcommittee 1999 World Health Organization International Society of Hypertension Guideline for the Management of Hypertension J Hypertens 17 151 183 1999 430 O Brien E Murphy J Tyndall A et al Twenty four hour ambulatory blood pressure in men and women aged 17 to 80 years the Allied Irish Bank Study J Hypertens 9 355 360 1991 44 Staessen JA O Brien ET Atkins et al Short report ambulatory blood pressure in normotensive compared with hypertensive subjects J Hypertens 11 1289 1297 1993 45 Mancia Sega R Bravi et al Ambulatory blood pressure normality results from the PAMELA study J Hypertens 13 1377 1390 1995 46 Staessen JA Bieniaszewski L O Brien ET et al An epidemiological approach to ambulatory blood pressure monitoring the Belgian Population Study Blood Press Monit 1 13 26 1996 47 Imai Nagai Sakuma et al Ambulatory blood pressure of adults in Ohasama Japan Hypertension 22 900 912 1993 480 Hayashi H Hatano K Tsuda et al Relationship between circadian variation of ambulatory blood pressure and age or sex in healthy adults Hypertens Res 15 127 135 1992 49 Kawasaki T Uezo
20. 000000000000000000000 000000000000000000000 000000000000000000000000 000000000000000000000000 000000000000000000000000 000000000000000000000000 0 00000000000000000 000000000000000000000000 000000000000000000000000 00000000000000000000000 0 000000 3 1 000000000000000000000000 000000000000000000000 000000000000 Windkessel 000000 000000000000000000000000 00000000000000002979200000 000000000000000000000000 000000000000000000000000 000000000000000000000000 000000000000000000000000 000000000000000000000000 0000 00000000000000000 000000000000000000002000 0 0000 00000000000000000 000000000000000000000000 0 000000000 0 20 000000000000000600 1227 Japanese Circulation Journal Vol 640 Suppl 2000 El 00000000000 12 0000 30cm011cm0 0000 27 5 0000000000000000000 0000 220000000000000 60000000000000000000 00000000 0000000 000 000 000 000 El El 4 1 1 El Cl
21. 106 61 iiy 69 000250 128 7 950 123 75 m Bilin 118 64 0000000 000150 128 72 000250 141 80 Imai 00000000 335 20 87 108 62 00000 950 141 79 000150 121 69 000250 3 7 00000000 1438 Ae mT 105 83 000150 114 70 imm 123 77 950 121 74 Kawasaki lma 18 93 950 88 134 48 78 000000 324 950 83 125 45 72 Staessen 00000000 9998 000250 126 77 000000 6551 950 123 74 Japanese Circulation Journal Vol 64 Suppl 0 1235 000000000000000001998 1990000000000 000 000 00 000000 24 00 0000 0 mmHg mmHg 0 34 43 320 67 160 95 40 0 SBP HSBP 29 1 20 0 SBP HSBP 24 59 45 160 69 140 90 awakeABP 140 90 34 2 292 47 905 DBPS104 awakeA BPO 134 90 21 3 60 36 180 68 140 90 24 130 85 38 4 81 71 160 SBP 900 DBP awakeSBP 142 43 2 5 89 46 290 59 140 90S 180 105 24ABPS 135 85 22 5 6 737 31 5 180 42 140 90 130 82 58 4 7 131 53 9 900 DBP 5 24080 85 34 8 56 46 900 DBP dayA 134 90 35 7 9 51 6000 160 90 245 140 33 3 10 50 79 700 94 160 95 lt 146 87 18 11 115 8s 160 95s HBP 131 79 27 8 12 83 20s 160 95s 24 133 78 38 6 284 47 90 lt DBP dayDBP 90 39 1 13 60 47 280 59 140 900
22. Turi Z Circadian variation in the frequency of onset of acute myocardial infarction N Engl J Med 313 1315 1985 172 Goldberg RJ Brady Muller JE et al Time of onset of symptoms of acute myocardial infarction Am J Cardiol 66 140 144 1990 1730 Willich SN Epidemiologic studies demonstrating increased morning incidence of sudden cardiac death Am J Cardiol 66 15G 17G 1990 1740 Deedwania PC Carbajal EV Role of myocardial oxygen demand in the pathogenesis of silent ischemia during daily life Am J Cardiol 70 19F 24F 1992 1750 Mulcahy D Keegan J Crean et al Silent myocardial ischaemia in chronic stable angina a study of its frequency and characteristics in 150 patients Br Heart J 60 417 423 1998 176 Willich S Goldberg R Maclure M et al Increased onset of sudden cardiac death in the first three hours after awakeing Am J Cardiol 70 65 68 1992 177 Lampert Rosenfeld L Batsford W et al Circadian variation of sustained ventricular tachycardia in patients with coronary artery disease and implantable cardioverter defibrillators Circulation 90 241 247 1994 1780 Marler JR Price TR Clark GL et al Morning increase in onset of ischemic stroke Stroke 20 473 476 1989 179 Kelly Hayes et al Temporal patterns of stroke onset the Framingham study Stroke 26 1343 1347 1995 1800 Schillaci G Verdecchia Benemio G et al Blood pressure rise and ischemic stroke Lancet
23. 0 0 0 0 0 0 000000000000000000000 000000000000000000000 390 97 2007 0000 000000 0000 000000000000000000 00000000000000000 000000000000000000 oOo 4 oOo 0 0 0 0 000000 0 0 0 0 0 Oooo 000000000000000000 000000000 9 00000002000000000000000 000000000000000000 Ooo 2400000000 Ooo oO 00000000000000000000 00000000000000000000 index 00000000 0 meta analysis 0 0 0 LVM index 00000000000000 00 000000000000000000000 000000 0 000000000000000 0000000000 Palatini 0 0 2 000000000000000000000 000000000000000 27000000 000000000000000000000 0 0000000000000000000000 0000000000000000000000 0000000000000000000000 00000000000000000007020 000000 0 000000000 0000000000000000 72720000 00000000000000000000000 0 0 000000000000000000000 0000000000000
24. 00000000000000 0 0 0 0 0 0 0 0 0 0 0 000000000000000 000000000000000000000 999 00000007 0 210000000 0 00 Oooo oO OO Oooo oOo OO oOo 0 000 0 000 0 000 0 000 0 000 Oooo Oooo 0 0 0 0 0 0 0 0 0 0 Oooo oO Oooo oO IEE ES Ged W asa Gey Oooo Oooo Oooo 0 0 0 0 0 0 Oooo Oooo oO 0 0 0 0 0 0000000 Q angiotensin 0 0000000 ransluminal renal angioplasty 0 0000000000000 PTRA 0000000000 00000020 Oooo oo oo 4 1 1 41 4 4 0 0 0 0 0 0 0 Oooo J ercutaneou oOo Ooo Oooo Oo 0 800 000 000 000 000 00000000000 000 0 0000000000000000000 00000000000000000000 aldosterone 00000000000000 0000000000000000000 0000000000000000000 OO 0 G OOO 0 0 0 0 0 0 0 0 0 0 0 0 0 000 000 000 000 000
25. 00000000000000000001998 190000000000 240000000 00 00000 00000000000000000000000000000000 00000000000 0 0 0 0 0 000000 0 0 0 00000000000 0 0 0 0 0 0 0 000000000000000 0 0 0 W 0 000000000000 00000000000 0 000 0000000000000000 0 0 0 00000000 0 0 0 0 00000000 0 0 0 0 000000000000000 0 0 0 0 000000000000 0 0 0 00000000000000 0 0 0 0 00000000 50 cd 0 I 0 00000 eg 000000 00000 0 0 0 00 10 ABPMU 0 3 300 0 1 19 0 000 0000 3 40 0000 0 1 29 ABPMO OOOO 3 500000 1 39 3 600 00 0 20 D 3 700 000 2 10 400000 000000000000 2 200 000000600 4 10 4200 00000000000 D 0000000 0 0 0 0 10 0000060 5 0 00000000000 20 0000000000000 00000 000000000000 00 240 2 10 ABPMI I 00000 dipper non dipper 2 20 0000000000000 extreme dipper 400000000 dd 00000000000000 cg 00000000000000 5 28 000000 000 5 30 3000000 D 5 40 00000 3 100 000000 000 9 00000000 3 200 00000600 260000 Japanese Cir
26. 135 91 24 14 171 45 90 lt DBP 24080 85 34 15 00 1550 DBP 24DBP 229 51 230 74 140 SBP 24SBP 135 28 16 90 lt DBP 240 85 14 1324 160 SBP 245 133 24 17 1310 95 lt DBP 24080 82 30 333 WCHTO 50 140 90 BPO 136 87 0 18 9 18 BPO 131 86 0 255 49 330 65 140 900 24 135 85 21 19 66 15016 145 85s 74 20 48 2100 140 90 130 90 52 21 159 47 25 22 53 14 23 100 180 65 37 0 140 905 24 134 90 awake 19 43 24 32 140 90 day24A BPS 130 85 22 25 232 54 2 140 90 lt 24ABP day 138 84 4 30 26 353 140 90 mean24A 97 5 0 44 27 361 140 90 24 140 90 awake 22 4 28 60 24 130 85 38 29 day24ABP 130 85 10 15 30 1236 Japanese Circulation Journal Vol 640 Suppl 2000 24000000000 000 0000000000 0000000 0000000 00000 0000 111 00000 900000 0310 24 0 320 30000 0000 200000 25 0 330 30000 0000 000000 204 00 000000 0 340 17 000000 0 350 OOO 0000 190 360 0000000 6400 13 O
27. 0 00000000000000000000 00000000000000020000000 000000000 streptokinase 00 000000000000000 00000000970000000000000000 0 000000000000000000000 aspiinlOOOOOOOOOOOOOOOOOOOOO 0 000000000000000000000 00000000 18515 2 0000006000000 0000000000000000000000 0000000000000000000000 00000000000000000000000 0000000000000000000000000 000000000000000000000 0000000000000000000000 0 000000000000000000000 00000000000000000 oO 00000000000000000 MESO Multicenter Investigation of Limitation of Infarct 0 0 000 000000000600 00 00029990 0 57 0 00000000000000000000 0 00000000090000000000100 0 000000002399000000000000 0000030000000000000000 0 000000000000000000000 0 00000000000000000000 0 0000000000000000000 3 000000000000000000000 cyclosporine 0000000000000000 0 000000000000000000000 000079 9000000000000000000 0000000020900000000000000 1220 Japanese Circulation Journal Vol 64 Suppl 2000 Oooo E Oooo OO 0 0 Oooo 0 0 2 memory 0000000000000000000 000000000000500000010 000000000000000000000 000000000000000000000 000000000000000000000 00000000000000 00000
28. 0000000000000000000000 00000000000 dipped 00000000 0000200000000000000000000 non dipper 00000000 000004 0000000000000000 000000000000 non dipper Q dipper non dipper 000000000000000 0000000000000000 0 non dipper 00 0000000000000000 0000 periventricular PVHI 0 0 0 0 0 non dipper 000000000 AO 00000000 20000000000079000 00 0 00 00000000000000 00000072000000000000000000 0000000000000000000000 0000000000000000000000 000000000000000000000000 0 00000000000000 non dipper 00000 00000000000000000000 00000000000000000000000 000000000000 00000 00 1218 Japanese Circulation Journal Vol 64 Suppl 2000 0000000000 non dippr 0000000000 000000000000000000000200 00 0000 000000000000 0 000000000000000000000 000000000000000000000000 0 0000000000000000000000 non dipper 00000000000000000 0000000000000000000 0 non 000000000000000000 dipper 0 000002000000000000000000 000000000000000000000000 000000 pper 000000000000000 000000000000000000000 000000000000000000000 00000000000000000000 00 00000000000000000000 00000000000000000007072 00000000000000000000 extreme dipper 00 0000000000000 0000 000000 000000000000000000000 0000000000000000000 0000000000
29. Japanese Circulation Journal Vol 64 Suppl V 2000 1245 000000000000000000000 1998 19990 0 00 0 00000 3 147 152 1998 273 Appel LJ Statson WB Ambulatory blood pressure monitoring and blood pressure self measurement in the diagnosis and management of hypertension Ann Intern Med 116 867 882 1993 2740 Pickering TG Blood pressure monitoring outside the office for the evaluation of patients with resistant hypertension Hypertension 11 part 2 96 100 1988 2750 Imai Tsuji I Nagai K et al Ambulatory blood pressure monitoring in evaluating the prevalence of hypertension in adults in Ohasama a rural Japanese community Hypetens Res 19 207 213 1996 2760 Staessen JA Byttebier Buntinx et al Antihypertensive treatment based on conventional or ambulatory blood pressure measurement a randomized controlled trial JAMA 278 1065 1073 1997 2770 0000 000000000 00 4 43 46 1997 278 Voogel AJ van der Meulen JHP van Montfrans GA Effects of antihypertensive drugs on the circadian blood pressure profile J Cardiovasc Pharmacol 28 463 469 1996 279 Minami J Ishimitsu T Kawano et al Effects of amlodipine and nifedipine retard on autonomic nerve activity in hypertensive patients Clin Exp Pharmacol Physiol 25 572 576 1998 280 Myers MG Dihydropyridine calcium antagonists and the trough peak ratio focus on adverse effects J Hypertens 12 Suppl 8 S73 S77 1994 281 Salvetti A Di Venanz
30. Some aspects of the cardiovascular and renal circadian system Circulation 34 715 717 1966 2090 Halberg F Drayer JIM Cornelissen et al Cardiovascular reference data base for recognizing circadian MESOR and AMPLITUDE hypertension in apparently healthy men Chronobiologica 11 275 298 1984 2100 Hayashi H Hatano K Tsuda et al Relationship between circadian variation of ambulatory blood pressure and age or sex in healthy adults Hypertens Res 15 127 135 1992 210 0000 0000 0000 00000000000 MEM FFT 0 0000000 0 0060 26 515 522 1989 2120 Ulrych TJ Bishop TN Maximum entropy spectral analysis and autoregressive decomposition Reviews Geophysics Space Physics 13 183 200 1975 230 000 0000000000000000 0000000 00000 7 50 54 1976 240 000 00000 0000 0000000000 0 000000 000000 0000 00 p 16 18 1993 215 O Brien E Perry I Sheridan J et al Application of cusums to ambulatory blood pressure data a simple statistical technique for detecting trends over time J Hypertens 7 707 709 1989 200000 2160 Statius van Eps RG van den Meiracker AH Boomsma F et al Diurnal variation of blood pressure in patients with catecholamine producing tumors Am J Hypertens 7 492 497 1994 217 Gallen IW Taylor RS Salzmann MB et al Twenty four hour ambulatory blood pressure and heart rate in a patient with a predominantly adrenaline secreting phaeochromocytoma Pastgrad
31. 0000000000 00000000 0002400000000000000000 000000000 0 0 0 0 0 0 0 000000000000000000 0 0000000000000000 0 0000000000000 9 0000000 00000000000000000600 00000000000000000000 0 0 000000000000000000 0 00 00000000000 000000000000000000 0000000000000000000 0000 ABPM OOOO 8 105 6 mmHe 0 000 60 000 000000000000000 0 000000020202 00000000 0 0 0000000000 0 000000000000000000 0000000000000 0 0000000000000000000 0000000000 000000 000000000000000000000 000000000000000000 000000000000000000000000 00000000000000000000 2400000000000000 0 000000000000000000000 0000400000000000000000000 000000000000000000000000 000000000000000000000000 000040000000000000000000220 00000000000000000000000 O TT Y sem G OO Oooo 0 0 0 0 0 0 Oooo 0 00 00 00 00 00 00 00 00 00 00 00 00 00 24000000000 dipper non dipper 000000000000000 00000 non dipper dipper 00000000000 0000000000 extreme dipper 0000000
32. Lindholm L How good are standardized blood prssure recordings for diagnosing hypertension A comparison between office and ambulatory blood pressure J Hypertens 9 561 1991 040 00000 0000000000 0000 72 17 1995 0 250 Long J Gillilan R Lee SG et al White coat hypertension Detection and evaluation MMJ 39 555 1990 0 260 Inden Tuda Hayashi H et al Relationship between Joint 270 280 0 290 National Committee VI Classification of Hypertension and Ambulatory Blood Pressure in Patients with Hypertension Diagnosed by Casual Blood Pressure Clin Cardiol 21 801 1998 Palatini P Pessina AC A new approach to define the upper normal limits of ambulatory blood pressure J Hypertens 8 suppl 6 S65 1990 Bidlingmeyer I Bunier M Bidlingmeyer M et al Isolated office hypertension prehypertensive state J Hypertens 14 327 1996 Krakoff LR Eison H Phillips RH Effect of ambulatory blood Japanese Circulation Journal Vol 64 Suppl V 2000 1247 000000000000000000000 1998 19990 0 00 0 00000 pressure monitoring on the diagnosis and cost of treatment for mild hypertension Am Heart J 116 1152 1988 300 Mancia Zanchetti A Editors corner White coat 00 0310 0 320 330 0 350 0 360 0 370 hypertension misnomers misconceptions and misunder standings What should we do next J Hypertens 14 1049 1996 0 Hoegholm A Ba
33. o 1 B G 1 o 3 a Oooo OGO et 00 T 23 El 1 3 C 3 3 0 0 0 0 0 0 O 1 1 1 Oooo oo Oooo Oooo oo Oooo oo oa 0 0 00000000000000000000 19840 0 199990 0 0 0 MEDLINE 0 0 0 ambulatory blood pressure monitoring and pregnancy 0000 0 0 00000000700000 00000 SA 0000 00 00 00000 BHSQ 0 000000000000000 000000000000000000000000 47 9 0000 OO O trimester 00000000000000000 000024000000000 100 70 000 00 13080 0000000000000000 00 0 SA 0000 ABPMOOOOOO 44000000 110 65 000000000 00000 000000000 00 oe 0000000000000000000 0000000000000000000 0 00000000000000 00000000000000000790 Oooo oo Oooo 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1228 Japanes
34. oa 6 Oooo 0 0 0 0 0 0 O oF 4 1 Z Oooo asa oy res S sssi Ee ser Oooo 5 0 0000000000000000 O OC GO 0G Oo N 0000 00000000000000000 1000 0000000079727200000000000 000000000000000000000000 000000000000000000000000 1226 Japanese Circulation Journal Vol 64 Suppl 2000 000000000000000000001998 190000000000 OO 24 00000000 10 0000000000 00000000 20000000 0000000 100 eu eu 100 000000 0000000000 100 mmHg 0000 00000000000000000000000
35. 0000 240 0 145 85 0 0 00 0 0 n 0 0 0 0 0 0 1 g 0 0 0 0 0 0 0 0 00 0 00 0 00 0 00 0 00 0 00 0 00 D O 0O O O ESP 0 0 0 0 0 0 0 0 0 000000000 125 75 mmHg 00000 000000000000000000000 5400 00000 40 0000000000 240 117 70 00 000000 180000 OOo Oooo oo Japanese Circulation Journal Vol 64 Suppl 2000 1213 000000000000000000000 1998 19990 0 00 0 00000 130 79 mmHg 000250 0 O 143 88 mmHg 0000 0000000 00000000000000000 0 000000000000019 9300 640000 000000000 ABPMQQ OQ 121 73 mmHg OO 113 69 mmHg 0 0 0 1590 25000000000 131 81 141 89 mmHg 0 0 125 780 137 87 mmHg 0000000000 0000000000 0000 000000000000000000000000 00030000 6 000 0000 0000000000000000000000 000000000000000000000000 0000000000000000 00 000000000000000000000000 000000000000000000 non linear 0 000000000000 00000197000000000000000 000000000
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43. 0 0 00000000000 00000000 22 9 15 1992 OOo a EE 228 0 0000 50 000000 240000 000 79 102 1990 0 0000 0 00000000000 0000 0000 78 78 79 1989 2290 I Iil 230 0 00 D 0 Noradrenaline NA Q 0 0 0 000000000 00000 29 727 730 1981 231 Kuwajima I Suzuki Hoshino S et al Effects of aging on the cardiopulmonary receptor reflex in hypertensive patients Jpn Heart J 32 157 166 1991 232 Conway J Boon N Jones J et al Involvement of the baroreceptor refolexes in the changes in blood pressure with sleep and mental arousal Hypertension 5 746 748 1983 2330 Parati G Di RM Bertinieri et al Evaluation of the baroreceptor heart rate reflex by 24 hour intra arterial blood pressure monitoring in humans Hypertension 12 214 222 1988 2340 Hoeldtke RD Cavanaugh ST Hughes JD et al Treatment of orthostatic hypotension with dihydroergotamine and caffeine Ann Intern Med 105 168 173 1986 235 Ikeda T Matsubara Sato Circadian blood pressure variation in diabetic patients with autonomic neuropathy J Hypertens 11 581 587 1993 236 Moiniche S Hjortso NC Blemmer T et al Blood pressure and heart rate during orthostatic stress and walking with continuous postoperative thor
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45. 000 640 Pickering TG James GD Boddie et al How common is white coat hypertension JAMA 259 225 1988 65 Pickering TG Ambulatory monitoring and the definition of hypertension J Hypertens 10 401 1992 Japanese Circulation Journal Vol 64 Suppl 2000 1239 000000000000000000000 1998 19990 000000 66 Pierdomenico SD Mezzetti A Lapenna S et al White coat hypertension in patients with newly diagnosed hypertension Evaluation of prevalence by ambulatory monitoring and impact of cost of health care Eur Heart J 16 692 697 1995 67 Verdecchia P Schilaci G Boldrini F et al Variability between current definitions of normal ambulatory blood pressure Implications in the assessment of white coat hypertension Hypertension 20 555 562 1992 68 Mancia G Zanchetti A Editors corner White coat hypertension misnomers misconceptions and misunder standings What should we do next J Hypertens 14 1049 1052 1996 690 0000 00 0 00 0 0000 0 000000 00000000000000000000000 Therap Res 20 2697 2713 1999 700 Pickering TG Levenstein Walmsley for the Hypertension and Lipid Trial Study Group Differential effects of doxazosin on clinic and ambulatory pressure according to age gender and presence of white coat hypertension Results of the HALT Study Am J Hypertens 7 848 852 1994 710 Nishibata K Nagashima Tsuji A et al Comparison of casual
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72. Ee ea OOOO OOOO 2 G oo oOo J J gt Ei E E 24000000000 cost effectiveness 0000000 000000000000000000 000000000000000000 0 00000000000000000 0 1 0 cost effectiveness D 0000 020000000000 1805 0 0000000000000 0 000003000000000 800 160 0530 000000 175034005000000000 0 00 00 00 00 00 00 3 4 Oooo oo Japanese Circulation Journal Vol 640 Suppl 2000 1233 1234 0000000000000000000 1998 19999 0 00000000 000 240 0 000 0 0 N 0000 0 SBP DBP O Brien 00 815 17 79 Ooo 118 72 O00 15 129 79 O00 25 140 86 950 134 84 Imai 00000 705 0 20 87 oo 122 71 00000000 000150 135 79 950 146 85 Imai 00000000 885 20 87 116 69 00000 2s w
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75. OO 00000 0 370 0000 20 000000 00000 0 380 0000 00000000 OO OE AQ 000 0 550 vw 00 0 D 0000 240000000 vw0000000 0 390 00002500 000 0000000000 00 000 000 0 0 0 0 0000 1076 5 4001 410 1522 412 10000000 NT 0 47 420 W CHT 0 49 HT 1 79 4 99 200000000000000 8654 5 00000 0 430 10 000000 hazard ratio 0 230 vs 440 802 12 OOO 0 450 00000000 odds ratio 1 60 vs 739 5 00000 W CHT 2 10 460 m o HT 4 40 14 0000 0000000 0 470 0000 AM QOO0000000000000 Hypertension Normotension WCHT White coat hypertension Japanese Circulation Journal Vol 64 Suppl 2000 1237 0000000000000000000001998 1990000000000 160 000000 OO 0 0000 0000 0 00000000 Korotkofi 00 000000000000000 A0 D TM24210 0 0 0 0 0 Ther Res 12 2585 2597 1991 0000 00000000000 000000000 000 00 1991 Shaw DB Knapp MS Davies DH Variations of blood pressure in hypertensives during sleep Lancet i 797 799 1963 Hinman AT Engel BT Bickford AF Portable blood pressure records accuracy and preliminary use in evaluating intradaily variations in pressure Am Heart J 64 663 668 1962 Schneider RA Kimmell GO Van Meter AF Jr An improved fully automatic portable blood pressure recorder J Appl Physiol 37 776 779 1974 Tochikubo O Kane
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80. culation Journal Vol 64 Suppl 2000 1207 oo gt w ar 00 20 10 1 1 1 2 gt a 1 3 200 2 1 2 2 2 3 1 00000 00000 00 000 000000 0000 00 000000 1208 Japanese Circulation Journal Vol 64 Suppl V 2000 00000000000000 1998 19990 0 0 00 00000 2 4 hypobaric index 0 0000000000000 30000 0000 3 1 000 3 20 000000 33000000 00 3 40 DO0000 400 000 00 00000 5 0 000 0 00000000000000 5 20 0000 00 5 30 0000 00000 V 000 100 000 0000000000 1 10 00000000 0 0000000000000000 0000600 bg 0000000 MOOOOOOO cd 0000000 1200000000 cosine fitting al 4 00000000000000 single cosinor b trough peak population mean cosinor smoothness index df hyperbaric index 0000000 eg 000000 000000 1 30 000000000 000000000 200 0 0000000 210 0 000000000000000 00 Oooo Ro JT gt
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84. ey 75 O00 25 137 82 Battistella 394 20 75 oo 117 75 000150 129 82 Zachariah 126 20 79 000150 131 79 M ancia 00000000 1438 25 64 ls 72 00150 123 78 00250 84 950 128 82 Hayashi a m m a m 540 40 9 128 D D 117 70 000 150 130 79 O00 250 143 88 Kawasaki 320 11 73 18 93 000150 131 81 O00 25 141 89 324 113 69 125 78 O00 250 137 87 Staessen 0000 3188 10 99 Oo 116 70 000000 000250 137 85 950 133 82 Staessen 00000000 9998 0 000 25 136 85 000000 6551 0 950 132 82 Japanese Circulation Journal Vol 640 Suppl 2000 24000000000 000 0 0 N m SBP DBP O Brien 00 815 1779 124 78 isp 136 86 250 148 94 950 143 91 Imai m oN 20970 127 75 0000000 000 150 141 83 imm 92 Imai 00000000 335 20 87 121 72 0000000 950 153 90 133 79 000250 144 87 Mancia 00000000 1438 Ae mT 120 7 129 84 imm 37 90 950 134 88 Kawasaki 0320 950 102 143 59 86 000000 BES oy 964135 53 61 Staessen 00000000 9998 000250 142 90 000000 6551 138 87 000 0 00 0 0 N SBP DBP OBrien 815 1779
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92. morning surge 0 0000009000000000 0000000000000000000000 000000000000 0 0000000 0000000000000000000000 0000000000000000000000 0 0 00000000000000000000 00000000000000000000000 0000000000000000000000 0000000000000000000000 0000000000000000 00000000000000000002 00000 7 De Quattro GaBOOOD labetalol 00000000 ___ 000000000000000000000 000 0 00000000000000000000 000000000 0000000000000000000000 1222 Japanese Circulation Journal Vol 64 Suppl 2000 00000000000000 00000150300 100 0000000000000000000 000040000000000000000000 000000000000000000000 0000000000000000000000 0 DiReinzo 00000000001500 1000 0 0 0000000 00000000 0 0 0 0 000000 5000000000 520000 000000000000000 sp OO 5000000000000000720 000000000003000 1000000 0300000000000000 0000000000000000 0000000000000000 0000000000000007 000000000000000000 0000000000000000000 00000 compliance 0000000000 000000000000000 0000 000000000000000000 000000000000000000 00000000000000000 000000000
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