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Contents
1. 1 000 1002. SAB Scientific Advisory Board SAB 9 370 3 9
3. SBS DIC
4. NHL Non Hodgkin Ilymphoma Diffuse Large Cell Type Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4
5. 2012 5 PMDA Pharmaceutical and Medical Devices Agency PMDA PMDA 6 700 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 SyB L 1101 SyB C 1101
6. 3 5 Weaknesses
7. TI MDS I MDS MDS 1
8. Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 symbiosis
9. IgG G Immunoglobulin G IgG SPA I FDA
10. Shared 6Qesearch la http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w amp 4582 Shared Research Report 2014 11 4 2010 23 919 60 18 240 76 3 2000 2010 80 2012
11. 1 5 2010 12 3 3
12. 2013 12 7 300 2014 12 2016 12 5 800 6 500 a T FF sShared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp w 4582 Shared Research Report 2014 11 4 2 B
13. MDS 10 20 3 5 10 MDS S R MDS MDS IPSS International Prognostic Scoring System TIPSS
14. 9 294 370 3 10 17 10 1 1 5 3 5 2014 7 I
15. 1 2 4 MDS 1 MDS 2 2011 7 II 800 SR a T Shared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 2012 9
16. PFS Progression Free Survival POC Proof of Concept B
17. ROA ROE SR 112 19 131 19 131 30 634 32 5 59 3 143 6 90 6 69 3 52 6 402 8 365 4 345 3 254 7 239 5 4 121 4 016 6 511 4 840 7 264 4 218 4 213 7 178 5 421 7 634 13 22 17 14 9 27 27 48 57 37 2 1 13 11 8 4 261 4 263 7 256 5 502 7 687 1 309 330 205 178 646 599 251 2 2 5 4 3 207 180 651 602 254 4 054 4 083 6 606 4 900 7 433 211 754 2 074 1 659 1 677 4 116 117 411 1 332 2 963 663 4 611 1 4 057 7 6 15 1 36 5 27 2 24 3 8 1 15 8 39 4 30 1 26 0 95 1 95 8 91 0 89 1 96 7 eSsearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved Shared Research Report 2014 11 4 4582 Shared Research Report 2014 11 4
18. 10 KOL Key Opinion Leader CRO Contract Research Organization
19. MDS 1 2014 2 MDS BSC Best Supportive Care 1
20. 1 2 SR 10 1 10 1 2013 R amp D 2006 2008 67 1 469 T 199 779 90 BIOtechNOW 2004 2011 I 6 79 12 19
21. 3 SAB 10 17 1 5 3 5 2014 7 3 2016 12 2 162 4 225 1 7
22. POC SAB George Morstyn CMO FDA Robert Lewis iPS
23. SR Tnc SR Inc http www sharedresearch jp Email info sharedresearch jp 3 31 12 03 5834 8787 Shared GYesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved
24. MR Medical Representative OS Overall Survival sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 Orphan Drug
25. SR Inc Shared Researcn SR Inc SR Inc SR Inc SR Tnc
26. Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w gt 4582 Shared Research Report 2014 11 4 105 0004 23 7 8 03 5472 1125 JASDAQ 2005 3 25 2011 10 20 HP http www symbiopharma com index html 12 TIR IR IR http www symbiopharma com ir index html IR e 1 Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 7 4582 Shared Research Report 2014 11 4
27. SyB L 0501 a 2010 10 27 TT T TT II B 2010 1 20 2011 5 31 2014 6 16
28. FDA Food and Drug Administration FDA EMA European Medicines Agency EMA 2014 4 1 2012 6 MDS 1 FDA EMA 1 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 MDS
29. Symbenda SyBL 1101 SyB C 1101 Symbenda JASDAQ 1Innomustine eSsearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 10 9 89 8 45 VZ2 6 01
30. SR 1 500 1 000 2008 8 SR 5 2
31. 2012 Y Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 2011 2012 2012 iPS
32. 20 1 2013 3 MDS MDS I MDS 1 I sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp w 4582 Shared Research Report 2014 11 4
33. 7 100 6 700 700 19 200 oO 4 230 a 2013 12 T TT SR Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved sy 4582 Shared Research Report 2014 11 4
34. Shared jesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 6 4582 Shared Research Report 2014 11 4 08 12 09 12 10 12 11 12 12 12 13 12 Pal ED 1 154 211 754 2 074 1 659 1 677 2 13 4 116 117 411 1 332 FCF 1 2 141 215 870 2 191 2 069 3 010 554 2 963 663 4 611 4 057
35. 2014 7 B IDEC Pharmaceuticals Corp Biogen Idec Inc Genentech inc 1997 11 IgG B CD20 SR 2001 9 2013 262
36. 2014 7 MR MR 120 130 30 40 MR SR M R sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp w 4582 Shared Research Report 2014711 4 2020 12
37. 1 000 1 500 SR 500 MR 40 1 500 SR 2020 12 900 2 600 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4
38. 2010 2014 21 100 2015 2019 23 000 2020 2024 24 500 30 000 25 000 20 000 15 000 10 000 5 000 0 r r r r r r r 1975 1980 1985 1990 1995 2000 2005 2010 1975 1980 1985 1990 1995 2000 2005 2010 4 013 4 741 6 635 9 297 11 195 13 307 16 991 23 919 10 3 6 4 1 5 7 5 8 9 10 5 13 3 18 7 SR 2012 7 691 2021 10 614
39. 50 565 2014 7 MDS MDS MDS MDS 2012 6 I 2014 7 MD
40. 646 807 713 812 http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 79 715 814 2 2014 2 T 2013 5
41. B CD20 B B 2008 1 2008 8 RI 1 4901 MDS MDS 11 000 60 2008 9 000 2008 2 781 2014
42. B R CHOP R CHOP 4 65 I 2012 3 H
43. InnoPharmax Inc Cephalon Inc 2013 12 132 8 6 2005 12 5 2010 10 2010 12 3 2013 12 4 230
44. Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014711 4 4 Shared 6Qesearch la http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved we s 7 4582 Shared Research Report 2014 11 4
45. 45 649 1998 ICH E5 Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4
46. Onconova Therapeutics Inc MDS Myelodysplastic Syndromes MDS 1998 125 MDS Myelodysplastic Syndromes MDS 30
47. 49 70 80 BB 20 309 T NK Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w Shared 4582 Shared Research Report 2014 11 4 94 B 699 T NK 25 4 2
48. NCCN National Comprehensive Cancer Network ESMO Europe s leading medical oncology society R B 2011 3 2012 3 2014 ho Shar ed Geseareh http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved G 4582 Shared Research Report 2014 11 4 7 BfArM Bundesinstitut fur Arzneimittel und Medizinprodukte 13 2014 12 81 2003 9
49. 1993 2005 3 2013 12 72 6 43 Shared csearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved G lt 4582 Shared Research Report 2014 11 4 10 17 4 10 17 lt 2 3 3 5 3 7 1 T
50. MDS MDS 1 2014 12 10 2014 6 3 Eisai Korea Inc sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w Shared esearch
51. a T Shared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w Shared 4582 Shared Research Report 2014 11 4 2005 3 3000 Bendamustine Hydrochloride _ _13AZ200010 SyB L 050 _ SyB L 0501 1 SyB L 0501 SyB L 0501
52. 12 2005 3 1980 AMGen Applied Molecular Genetics 1993 5 2008 2 32231UUNL0SGLAEKSM2 2005 1 4568 JASDAQ 4557
53. IL 1 825 30 49 1 118 36 9 SyB D 0701 HSP32 SyB 0702 2009 12 1 191 26 9 1 191 2009 3 2009 10 1 399 6 5 817 5 9
54. 1 500 1 000 1 000 2 000 sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp we s 4582 Shared Research Report 2014 11 4 SW Strengths Weaknesses SR Strengths Weaknesses Strengths 1 SAB SAB
55. POC sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 POC OE
56. SR 2005 12 1 4503 Astellas Deutschland GmbH 2007 4 4 2008 8
57. 6 000 6 500 2020 12 SR 2020 12 5 000 6 000 SR 2020 12 15 000 18 000 20 000 15 000 300 350 10 000 5 000 14 12 15 12 16 12 17 12 18 12 19 12 20 12 SR Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved G 4582 Shared Research Report 2014 11 4 2020 12 3 900 5 100
58. 2012 389 2021 602 Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 7 691 105 0 1 614 138 0 1 195 112 4 1 994 166 9 389 111 5 602 154 8 2014 7 1 4519 2011 229 2012 247 2013 262 4 700 2013 12 4 230
59. II I 2016 12 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 700 SR 300 350
60. KLab TOKAT SR Inc
61. 2011 1 MDS DNA 3 6 MDS MDS 2014 3 9 692 38 1 2015 3 10 800 Shared Gewearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 2013 12 1 532
62. IH 1 2019 2020 12 2008 12 2008 12 2014 12 1 654 2014 12 2016 12 1 500 2 500 SR 2020 a T FF sShared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp w 4582 Shared Research
63. 4 75 11 500 4 600 1 200 SR 80 90 25 5 000 6 000 4 000 5 500 2 700 3 900 SR 2020 12 8 500 10 000 3 900 5 100 2020 12 900 2 600
64. 2009 12 30 2011 10 18 MDS SyB L 1101 MDS ee SyB C 1101 MDS ii SR 2014 7 MDS MDS
65. SR GCA MG
66. 35 114 1 601 1 729 1 605 1 733 se Shared Yesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 08 12 09 12 10 12 11 12 12 12 13 12 p 1 630 1 191 1 450 1 883 1 955 1 532 26 9 21 7 29 8 3 9 21 6 238 1 224 1 362 1 214 1 630 1 191 1 212 658 593 318 100 0 100 0 83 6 35 0 30 3 20 8 1 497 1 399 1 825 2 725 2 293 1 999 91 8 117 5 125 8 144 8 117 3 130 4 133 208 613 2 067 1 700 1 681 s 8 2 5 6 20 13 56 7 114 115 26 38 85 37 35 24 214 638 2 095 1 729 1 601 8 1 5
67. e 1 Shared esearch la http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved we EF 4582 Shared Research Report 2014 11 4 13 12 14 12 14 12 Pal ED lo 6 10 4Q io 6 3 4Q 489 322 513 109 174 802 54 6 1 785 15 8 32 0 10 59 75 2 64 59 149 1 8 7 151 33 89 45 32 215 17 69 75 796 59 596 58 596 78 696 543 696 30 9 10 4 17 3 41 3 18 6 26 8 492 500 475 532 448 445 19 2 5 9 18 7 6 5 9 0 10 8 100 6 155 2 92 6 490 7 257 9 55 6 341 466 386 488 416 231 1 654 352 460 376 414 454 259 1 650 353 461 377 414 455 261 1 654 SR 2014 12
68. MDS 2 SR SR 2016 12 2 162 4 225 2016 12 1 000
69. 3 1 3 5
70. MDS Shared 1 jesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved G 4582 Shared Research Report 2014 11 4 SyBL 0501 SyB L 0501 1971 B 2005 B 2 200
71. 2010 10 2014 7 2016 12 2014 2 1 2018 12 2019 12 MDS
72. 2010 12 2013 12 SR 4 2008 8 75 dq W Shared Gewearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11
73. 3 SW Strengths Weaknesses a T Shared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared 09 12 10 12 11 12 12 12 13 12 14 12 1 191 1 450 1 883 1 955 1 532 1 785 26 9 21 79 6 29 8 3 9 21 6 16 5 1 191 1 212 658 593 318 208 613 2 067 1 700 1 681 1 654 214 638 2 095 1 729 1 601 1 650 218 642 2 105 1 733 1 605 1 654 EPS EPS DPS BPS
74. FDA 2013 12 ASH American Society of Hematology IL MDS 60 1 2 14 7 8 36 14 39 32
75. 2014 2 MDS BSC Best Supportive Care 299 199 100 BSC OS5 8 2 BSC 5 8 P 0 27 299 184 629 OS 8 5 BSC 4 7 P 0 022 60 3 7 39
76. SR 2020 12 2020 12 10 000 12 000 5 000 6 000 2016 12 4 700 4 500 5 000 7 100 700 2014 7 SR
77. I I 2008 12 1 630 2007 12 1 630 2008 8 1 497 868 Shared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 09 12 10 12 11 12 12 12 13 12 lcD 1 933 2 338 1 927 1 883 1 955 1 532 2 6 16 4 20 5 2 351 1 625 1 889
78. A 4 4 7 8 9 8 B 8 3 14 12 3 C 5 56 78 142 FCF NI A B C 17 217 655 2 165 1 650 1 739 1 370 4 121 3 916 6 311 4 240 5 294 SR 2012 12 2013 12 http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 7
79. 8 1 0 5 0 2 4 4 4 4 4 8 21 218 642 2 105 1 733 1 605 5 2 SR 2012 12 1 955 3 9 19 8 3 940 16 2 2 293 15 89 1 438 26 1 2011 12 5 2011 12 1 883 29 8 1 632 401 3 3 390 2010 12 64
80. 250 http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 2 725 49 4 1 945 73 9 SyB D 0701 HSP32 SyB 0702 2010 12 1 450 21 7 326 1 124
81. MDS 7 800 MDS 3 200 1 4516 MDS 2014 3 9 692 38 1 2015 3 10 800 SR Shared esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved we s 4582 Shared Research Report 2014 11 4 4 Plgb 08 12 09 12 10 12 11 12 12 12 13 12 1 630 1 191 1 450 1 883 1 955
82. sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved e we s 4582 Shared Research Report 2014 11 4 2013 12 2014 12 2016 12 3 13 12 14 12 15 12 16 12 2 162 4 225 1 680 1 654 2 355 2 455 1 757 1 601 1 650 2 351 2 451 1 753 1 605 1 654 2 355 2 454 1 757 14 12 15 12 16 12 17 12 18 12 19 12 20 12 e la RN Ns Nr a MDS MDS
83. 4 21 696 4 230 7 49 6 1 432 26 8 100 II 1 053 26 8 946 10 6 1 999 12 9 1 681 1 700
84. 2011 7 H Onconova Therapeutics Inc 1 2012 9 Baxter International Inc a T Shared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved w 4582 Shared Research Report 2014 11 4 50 565 3
85. 2016 12 7 100 1 5 SR 5 500 6 000 2012 6 2016 12 2013 5
86. 2 067 1 700 1 681 2 398 1 652 1 922 2 095 1 729 1 601 2 407 1 656 1 926 2 105 1 733 1 605 SR 2011 10 2011 12 Ne Shar ed esear ch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved s 4582 Shared Research Report 2014 11 4 08 12 09 12 10 12 11 12 12 12 13 12 1 070 3 902 2 314 4 559 4 540 6 163 300 219 1 701 1 953 300 1 100 6 162 148 207 165 125 90 97 191 297 268 245 1 460 4 218 4 213 7 178 5 421 7 634 7 7 7 8 8 18 31 32 34 34 12 16 22 2
87. 1 4282 SBI 1 8473 1 10 2005 12 2008 9 50 2008 12 15 2010 10 2010 12 2014 7
88. 4582 Shared Research Report 2014 11 4 16C3 03 W P JE W PF 2009 3 7 404 66 017 888 4 643 2009 11 8 334 90 268 500 6 104 2009 12 9 553 100 651 573 6 727 2011 2 11 032 122 769 772 8 164 2011 2 17 368 140 137 1 216 9 380 2011 10 5 100 000 19 130 900 2 628 12 019 2013 3 921 257 23 052 157 1 244 13 263 1 12 2013 12 6 720 200 29 772 357 2 504 15 767 SR Shar ed esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved G 4582 Shared Research Report 2014 11 4
89. 7 4582 Shared Research Report 2014711 4 2014 12 14 12 13 12 14 12 811 721 1 532 1 785 626 588 1 214 184 134 318 22 7 18 5 20 8 992 1 007 1 999 2 083 122 3 139 7 130 5 116 7 557 496 1 053 807 873 1 680 1 654 99 6 121 0 109 7 92 7 812 789 1 601 1 650 100 2 109 4 104 5 92 4 814 791 1 605 1 654 100 496 109 7 104 8 92 7 SR 14 12 12 12 13 12 14 12 SR 1 785
90. 16 59 1 559 19 9 211 59 8 2014 6 Symbenda 15 http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 2 083 4 2
91. 2 7296 1 2 2396 1 1 63 0 87 TN P 1 0 82 0 65 0 64 SR 2014 6 1971 MIT MIT T4 1975 1977 1980
92. 2005 3 5 POC I SAB
93. 2008 8 IV R CHOP R B R B 274 R CHOP 275 45 PFS R B 69 5 R CHOP 31 2 p 0 0001 p 5 R B 2015 12 2011 11 IT 2015 12
94. 2 2014 12 2 975 20 3 0 a 960 35 1 ANN ER eC ole 3 5 15 85 0 893 9 9 370 33 5 523 20 3
95. 5 6 SAB POC 5 POC POC 2 1 2 5 1 15 20
96. 509 4 700 4 500 5 000 esearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved 4582 Shared Research Report 2014 11 4 2014 7 B 7 100 700 Et 2015 12 2016 12 TT
97. T gE gt 4 700 6 700 2010 10 2010 12 SR CHOP R CHOP R B
98. 294 370 3 1 1 1 4523 gt Shared Research http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved amp 4582 Shared Research Report 2014 11 4 Scientific Advisory Board EE 5AB SAB 3
99. MDS IPSS 1 5 HLA T MDS I 2014 7
100. http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved G 4582 Shared Research Report 2014 11 4 2013 12 2014 12 2015 12 1 000 1 500 2014 12 2015 12 2016 12 1 757 2 455
101. sShared Search lt Shared Research Report 2014 11 4 4582 sr_inquiries Gsharedresearch jp 4582 Shared Research Report 2014 11 4 RS 3 EE 4 EE CPP 5 oo 5 0 6 RS SCI Ro 14 POP0CHe0HRCRE em 14 16 RN i i i 21 SS CN 32 SW St
102. MDS 11 000 sShared 6Qesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved Ss w 4582 Shared Research Report 2014 11 4 I W MDS 7 800 1 1 MDS 3 200 SR 2014 7 MDS MDS 1 4516 2006
103. 1 532 326 1 632 1 955 1 432 644 3 390 3 940 4 230 8 50 6 48 2 49 6 33 9 1 630 1 191 1 124 250 100 1600 1 085 1 446 1 872 1 930 1 486 30 106 4 10 26 46 238 1 224 1 362 1 214 73 1 75 0 69 7 84 8 37 0 36 1 34 6 28 7 238 1 434 1 322 1 175 1 630 1 191 1 212 658 593 318 1 497 1 399 1 825 2 725 2 293 1 999 252 323 343 365 413 441 868 817 1 118 1 945 1 438 1 053 377 259 364 415 442 505 133 208 613 2 067 1 700 1 681 SR 1 2008 12 f 2010 10 2010 12
104. 4
105. 57 2 454 2016 12 2015 SR 2014 7 2020 12 900 2 600 SR 3
106. 8 2007 PN CT Re PO 2010 10 2010 12 2014 7 2016 12
107. 8 33 13 13 22 17 14 9 25 27 27 48 57 37 3 2 1 10 8 6 3 3 2 3 2 1 13 11 8 41 42 50 78 82 53 1 501 4 261 4 263 7 256 5 502 7 687 1 309 330 111 182 124 278 196 207 82 23 52 59 73 44 193 205 178 646 599 251 1 2 2 5 4 3 1 2 2 5 4 3 195 207 180 651 602 254 1 307 4 060 4 083 6 606 4 873 7 336 1 893 3 378 3 7 1 6 025 6 025 8 059 1 863 3 348 3 681 5 995 5 995 8 029 2 448 2 666 3 309 5 413 7 146 8 752 27 97 1 307 4 054 4 083 6 606 4 900 7 433 5 61 17 125 1 070 3 902 2 314 4 559 4 540 6 163 SR
108. Report 2014 11 4 12 8 500 10 000 900 2 600 2014 12 2016 12 3 5 800 6 500 2013 12 7 300 S R
109. S TT MDS MDS 1 2013 3 MDS MDS PE 3 200 2019 12 1 7 800 2019 2020 12 3 200 1 TT 1 SR MDS MDS IPSS 2 HLA Human ho e Shar ed Geseareh http www sharedresearch jp Copyr
110. ight C Shared Research Inc All Rights Reserved amp 4582 Shared Research Report 2014 11 4 Leukocyte Antigen MDS 2014 7 MDS 2014 7 MDS MDS
111. rengths Weaknesses 34 uu 36 0 NN 40 41 Ph 44 WM K 7K QRQEQNQIN RA 45 71 PR 47 ya 47 3 49 PR 49 0 i 49 3 RE RR RR SS RR RR RN RR 50 55 se 1 sShared Wesearch http www sharedresearch jp Copyright C Shared Research Inc All Rights Reserved e we s 4582 Shared Research Report 2014 11 4 POC Proof of Concept POC
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