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血液利用の制度と技術
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1. 0000000000 8 00000000000000000 0 0 Institute of Medina 00 00000 000000000000000 Institute of Medicine 19957 199811 00000000000000000000000000000000000000000000000000 00 0 000000000000 6 00000000000000000000000000000 0000000000 000000000000000000000000000000000000000 000000000000 1995510 008 000000000000000000000 8 0 0 00000000000000 0000000000 000000000000000000 000000000000000000000 00000000000000000000000000299 0000000000000 00 0 2054 26000000000000000000000000000000000000 0000000000 cryoprecipitate Q D D D cry 0000 prec 0 000000000000000000000000000 ones 1974 1980 88 8900 0000000000000000000000 0000000000000 0 Wintrobe 1980 1982 61011 000180 0 3 9 0 000000000000000000000
2. 998 1999 291 298 T Foo Ee ae LES End a cs AN aan oma E 3 CEST cn PAC 1 5 4 Ec icr OO CJ p 3 c Oo 8 Po SA CJ CJ Si ET p Hu cl og CJ CJ Ao E EA E E OO Ooo 00000000000000 Titmuss 1968 19719 1841 DO NOD NONONO 0 000000 8 8 0 0 Titmuss 1968 19710 1860 OO Titmuss 1968 19719 1860 3 an Oooo oO 5 9 5 9 Oooo Ooo DJ Dx E 5 11 ea NG a Oooo Oo oO
3. 19719 1910000000 1 0 0 0 NO 19719 AO PTT Partial thromboplastin time 0 00000000000 D D Cross over electrophoresis 100 19749 000000000000
4. 00 0 98900000 1948 HgO 0 0 M4900 4
5. 0 0000000000 1971 21 2277 G oo 5 EI 1t kaa ES ka PA EE A Fas A EST EX Ed OO OO OO OOOO EJ Ea ma sr GN cs 3 9 0 0 000 000 0 0 2380 19999 D0000OC000000000000000000 Hicho 19999 2380 0 0 00 D 0 0 5 9 E ea 5 1 ODO 5 Go 1 1 2 4
6. DO 19 a0 erri 000000000000 0 0 0 195400000 0000000000 200cd 1200 0 14000 0 00000000 200c 0 000 4000 500 1992 2610 0000000000000 000000019 40000000000000000 958 00000
7. 1977 6 Ed 0 0 0 0 Oooo 1 0 00
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10. 0 1975 4 0 0 088 Starr 1998 79 Core Ethics Vol 2 2006 1999 2420 NUODDDOOOODODODODODODOODODODDODODODODDODODDDDO DU aa E E Oooo 1 1 ET ed EST EST E ann NA rosa Namn PAGG mana PA a Oooo oO 2 DO DO DO DO oO Lr 34 Todo DU D D Oooo oO EJ SE 5 5 Em sA Aa E E oo TA Ro AR EJ 6 ED 3 L1 L3 Oo r3 30 0 0 0 0 0 L3 L1 L3 D
11. 1295000000 00000000000 195900000 OO System and technology of blood use Hemophiliacs and coagulation factor products in postwar apan KITAMURA Kentaro Abstract The purpose of this article is to describe the history of the blood use of hemophiliacs in J apan It describes the start and development of the blood supply system and the development of plasma fractionation technology in the postwar period up to the first half of 1980 s General Headquarters GHQ directed the establishment of a safe blood supply system in 1948 Paid blood donation supported the blood supply system in J apan until the Reischauer affair in 1964 after which the cabinet decided to change the basis of nation s blood supply from paid blood donations to free blood donations After the discovering of cryoprecipitate in 1965 coagulation factor products for stopping blood were developed It was so effective that young hemophiliacs at that time actively aimed at the introduction and spread of home infusions even though they feared hepatitis because they wanted to participate in society The cabinets 1964 decision however created problems which became apparent 1970 s First no measures were considered for securing the raw material plasma for plasma f
12. O37 ma an Ed et et 96 1 1 isan 1950 1 1000000000000 Oooo 5 EE E Oooo
13. 1100000000 Young Hemophiliac Club O 6 8 0 34000 0 0 0 0000000000000000 0 1977 2627M 5 EJ LE Ee Ea a cel Ez ET JE E EE ESI
14. 4 ips o NS 57 51 8 E EE CE Ooo Oooo 79 L1 lt 9 0000 10 0 0 DON DONDODDNONDDONOD 200000000 0000 0 0 Ooo G ET LJ E I E eman PA ans PAA Ea 0 D 5 1 o o OOOO WHON 00 00008080 0 0000000 0 aaa 1 AA CU Er OB 1 GE om e t o EJ Ed 4 34 ce t Oooo oo oO Oooo oo BAH EY EI
15. 19 aQ 61107 1960 00O Starry 1998 1999 411110 0 010000000000000000000 OOO 110 01000 000000000000000 0 0 0 0 00000 000 8 8 sa AG Lj OO HAH E 5e e naa E EST 1 1 1 PEST ss SET EST ts SEE EST TESTS EST EJ sa NA corn KANG cea LJ Ca EX DEG 05 san PA KA as EI EI Ooo ET dE 1550512021 I 43 E OO
16. 0 0 97000 000000 8700000000000 OO 19600 1979000000000 000000000000 g 1980 0 0 0000 aao O 197 El 53 1 SES iE 3 000000 D00000 D00000 10 0 Oooo na EST El 83 Core Ethics Vol 2 2006
17. 20 268 1992 0 00000000000000 U uuu Feldman A Eric and Bayer Ronald 1999 Blood feuds AIDS blood and the politics of medical disaster 2003 0000000000 Glied Sherry 1999 The Circulation of Blood AI DS Blood and the Economics of Information 2003 0000 QO000000 Feldman and Bayer 19990 000000000000 OOOO OO 2003 pp253 279 OOOO 2003 OOOO 2 os 00000000000000000000000 00 00 2005 pp7599 0000 195 Illich Ivan 1982 Gesundheit als Tel der Lebensqualitat 1991 9 9 1999 QO O0O000000000000000000000000 4 Institute of Medicine 1995 HIV and the Blood Supply An Analysis of Crisis Decisionmarking 21998 ll HIVE D OOOO W3x70000000 J ones
18. 1010110000000098 1 0 00090000 0 Ooo 0000 0000 0000 0000 OM OOO 0 0 DU D D D 19727 1217 oO DO ITAGO ESI Eales Eh kaan NAN kaa
19. Oooo 0 Young H emophiliac Club 8000 20910 0 0 00 0 0 00000008000000000000000 OOOO ieziugugg ugugnpggggagiuoddgogu udnt pp119 123 DOHIVODO TODO 3 00 DOO 1960000000 0 D000000000000000000000000 0 198 ppis 37 Starr Douglas 1998 BLOOD An Epic History of Medicineand Commerce Knopf 1999 OOOO 200500000 0 00 0 0 0 2005 0 30 OOOO 2004 ALS QO0O00000000000000 Titmuss Richard M 1968 Commitment to Wd fare George Allen and Unwin Lid 1971 TO 00000000000 00000000 Wintrobe Maxwell M 1980 BLOOD PURE AND ELOQUENT McGraw Hill Inc 1982 0000000000018 0000 0000000000000 20039 2003 1 O HIVOD OD 0 0000000000000 0000000000 0 8 Young Hemophiliac Club 1975 1 OO Young Hemophiliac Club 1977 000O0000000000 00000 000 YHCDUD
20. 9 0 000000000008 dO ones 1974 1980 89 90 9 2 000 0
21. NONONO NDN NDN 0000 20030000 75 9 0 9 9 LE ate HF ES GE RB o Ooo 5 41 r p E AO CR TEs ETL gt 1 as 9 Oooo Oo 5 4 3 CES Og Tg HD e aan NA a CESE C F ea Jaan Ee Oooo oO 5 9 ES ra Oo 8 Ooo Oooo OOO Core Ethics Vol 2 2006 1992 4 5300 000000000 1110 0 0 0 000 0000 0 0000000900 8 0 1920 000000000000000 9 2 1 0 000000000000000000000000000 00 00 0 193
22. OD 1992 am oooocccooootoooooooooooooooloooocoocoon ogo LE pr rrr E 2 CJ r4 2 81 Core Ethics Vol 2 2006 1973 0 0 0 0 0 00090 0 0 2M 10 0 EJ lA Pa EXE BEI
23. 9 0010 000 0 9 OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO 61011 1982 1980 6 1967 0 0 0 0 LJ El ra L OOO oO ooo QO 1 1 CE EE ele ESL EST EI Oooo na E TES CEST EST CA 2 o o D L1 aaa o 0 0 00000 000000 D00000 009008
24. 00 0 000 00080 00 0009000000000 9 000000000 196710 6 ESI iE a gt ran PAN ey ECT ES Et E ESI DE 1 1 EDU ta es 1 2 ey Ee 3 EET ANG esn 78 OO 1 9 DOON NDN NDN NDN DN NDN NDN DDODDODO 19720000 1 0 0 Partial thromboplastin time 0 00000000000
25. 1994 27277000000000 1997 18800 00000 0 DU DOO 19 24 28 TT 1964 DOOOOOOOGOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO 0 19949 2100 00000 ml O ESI lt a G ESI EET BRA 5 AA ABS EI 4 r3 EF E
26. D 0 0 D00000 000000 000000 000000 0000 0000000000000 san G EX E 8 Oooo oO 0 0 0 0 0 0 2 0 0 0 0 0 0 0 DON NDN NONONO 77 Core Ethics Vol 2 2006 0 0 Ez Ez EJ 1 1 ESI OO OO Ex E EJ EJ CC EJ o EJ oO o EJ 3 o 1 o o ooo 0
27. 0 OOGOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOMYHG 1975 UB 188190000 900000 198100 3 1 1 1 0000000000000800000000080008000000899999 9 0 101000 200m0 O 5000 0 200m0 15000 000000000 0 0 19920 27227411 D D OOOGOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO ISA 16 0 0 0 000000000 0000 000 http kekkai ndl go jp OOOOOOOOOOODOO000000000 0 193 000000000000000000000000 17 270 2717 1982 0000000000 18 1977 WHO 11 111 0800 000000000000000080808808 000800000000080 000000000 19 9 1107 19 0000000000000 1959 0 1983 1041
28. BAAD 0000000000000 24000 0 0 19750 0 0 NONONO
29. Peter 1974 Living with Hemophilia Medical and Technical Publishing Co Ltd 1980 00000000000 OO000 OOO 1970000000000 OOO 1980 000000020 000000 DOO 19850 0000000000000000 0000 0000 O 31 33 200231 pp26 43 OOO 0 2003000000000000 Oooo 20am NOON 0000000000 000000000 9 3 pp 3 00000000000000 000 0000000000 000000030000000 20650 vol 7 No 2 pp6 70 0000000 000000 1988000000000000 pp45 47 1983 2005 http kokkai ndl go jp 2005 09 10 85 Core Ethics Vol 2 2006 000000000000000 195 000000000 000 1000 OOOO0
30. 0 0 000000 0 0 00000000000000000000000000 00000000000000000000000 000000000000 000000000000000000000 0000000000000 0000000019830 00000000000000000000000000 10 2900000000 0000000000 000000000000000000000000000000000000000 0000000000000000000000 00 1980 19830 000000000000000 000000000000000000000 000000000 0 00000000000000000000 00000000000000 0 9827 1982 0 00000000000000000 98100000000000000000000000000 19820 0 0 0008 0000000000000 0 19850 0 0 19860 0000000000000000 00 UU 1999 2003 253 254110 0 19850 0 O 000 0 0 0 0 0 VIN O 0 00000 10 210000000 IXCL CL D 19850 500 19830 0000000000000000 HIv00000 00000 0 0 0 1950 0000 00 0 000000000000000000000000000000 000 00 0 0 19959 STD 00007000000000000000000000000000000000000000000000 00000000000000 500000000000000000000 1995 8 0000000000000000000 0 19950 9 o 35 1000000000000000000000000000000000000 185900 2000 0000000000000000000000000000000000000000000000000 0 0 1990 32 80000000000000000000000000000000000000000 10 0 0000000000000000000000000000000 00 8 0000000000000 0000000000000 0 0 19955 3010 o0000001000000000000000000000000000000000000000000 000000000000000000000000000 000000000000000000000 34 1955 00000000000 12 00000000000000000000000000000000000000000000000000 0000000000000000000000000000000000000 1398
31. 0 00000 00 0 1964 2 00000000000000 Starr 1998 1999 266 270 TT
32. 0 sam 13 0 00000000000000000000000000000000000000 0000000000 0000000000000000000000000000 Starry 1998 19997 61 1 190100000000000000000000000000 19500 0270000000000 ad L3 LEGES LI L LJ EE x LE E LLLI ERE EI ETL LAIT r3 LANI LL LT KA LA 4 4 121 EJ LI 7 LJ CJ cLI EI AN oh o kk Lan AYA ag cs LIE LI EQ LI ELI r3 LIT LEY EQ ao crc r3 r3 o r3 LI LI KI EHI oo Co Eba os CA CI KAG LI CI Cai T CAL ICT kb KI 21 C3 L3 Ll TI Ll L3 LI Cu 8 E3 LI CI KJ CI OO 0 0 00
33. Core Ethics Vol 2 2008 0 UNO Ehe E D uuu 1980 0 0 199M 1110 0000000 0 HIVO 0 0 000000 0 0000 00000080 19960 0 0 19970 0 0 0 0 0 0 20030 000 208m0 DOO ONO NN DNODODDNODDNDONO 19920 000 19 Starr 1998 19990 0 D D UU D 0 9 H F ESTY 11 11 TE E Oooo oo D Ka NA ES d yopreipitatqY O 0 000 19650 0 0 000000000000 1983 1968 1933900
34. L AN E i DO Es E DT DO DO 0 DO DO J DO DO DO D uuu 00989 19B89Y DO DOO O 700 0000000000000 DN NDN DNONNNNNODO 0 19600 0000 0 0 97000000 HCVO DD OD 00000 Titmuss 1968 19710 18330 OOOOOOOCOOOOOOOOOOOOOOOOOOOOOOOOOOOOO
35. oo E EX AAO PA 000000000000 19640 0200000000000 o L3 L3 L3 L3 E Ek ASE E Og gt ma TA a AP TG ea CEST PRA oe 5 L3 CJ Aa E EX ES CLE HF gg Exi Ga IE CLE BE a a en LJ LEGES HO El 1 2 1 OO 51 0 0 00000000000000 0 1992 187 1881 1000 0000000 oooooocoiFaOOOOOOOOOOOOOOOOOOOOOOOOOIOOOOOOO
36. ractionation Second targets for blood donation were for stored blood only Third the financial underpinnings for the development of a blood supply system based on free blood donation were not clarified Key words Hemophilia Coagulation factor products Home infusion Blood supply system 87
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