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MicroCal™ VP-Capillary DSC Routine Maintenance
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1. 9 2a DU p mg d DE 9 2 er Eg o oO o Eo SO o Sg 99 aS oo 2s M co 6 3 EL EN 2 un Pm gt otc o oN on vo EE n S o s Ado O x o 2 So otc JO E cone ee ao av o g or kr del O3 O3 93 2 c i cv a L p co jud eec c 0c 060000000000000000000 0 OIOIOIOIOI DIOOIOJOIOOIDIOO0O0 OJO O0 OJOIOO OJOIO OIOIOIOIOIDIO O0 O JOJO OIOJDIOO0 O O0O0 O OIOO OJOIO OOODODO0O0O0O0o0 O09 0e0o08 5o0000l0Q0oiopoc o 9 eveec0 000000000000000000000 0 Preventive Maintenance GE imagination at work and GE monogram are trademarks of General Electric Company MicroCal is a trademark of GE Healthcare Companies k s Contrad and Decon are trademarks of Decon Laboratories Ltd m a o n a ti O n at WO rk 2012 General Electric Company All rights reserved GE Healthcare Bio Sciences AB Bj rkgatan 30 751 84 Uppsala Sweden First published Sept 2012 29 0256 72 A 09 2012
2. GE Healthcare Life Sciences MicroCal VP Capillary DSC Routine Maintenance Regular maintenance by the user of MicroCal VP Capillary DSC system is essential for performing high quality experiments and for obtaining high quality results Cell cleanliness has a significant impact on data quality Some of the required maintenance procedures are monitored by the software For these procedures the software will automatically issue a visual or audible alert to let you know when it is time to perform maintenance Daily After every run Centrifuge or filter all solutions before use to avoid particles and precipitates in the cell or syringe Run at least one of the cleaning methods after every run to clean the DSC cells Set up cleaning by clicking the Advanced tab on the left hand side of the Autosampler setup box Select the Sample Parameters tab and check the option Clean before Next Sample under Cleaning Options for each sample run MicroCal VP Capillary DSC system has a characteristic baseline when both cells are clean and filled with water Repeatable baselines are indicative of clean well filled cells Use cleaning solution if cleaning with detergent is not sufficient Weekly e Refill the three bottles on the solvent reservoir station of the Auto Sampler de ionized water in Solvent Reservoir 1 20 Contrad 70 or 14 Decon 90 in Solvent Reservoir 2 and cleaning solution in Solvent Reservoir 3 Both bottles for the rinsing solution should
3. be filled with de ionized water When necessary e Every 250 to 300 runs replace valve needle seal A software notice will appear when it is time to perform this procedure e Every 250 to 300 runs or sooner if the seal is leaking replace the syringe plunger A software notice will appear when it is time to perform this procedure e Every 600 to 900 runs or as needed when the syringe is bent or corroded replace the syringe Operation Necessary reagents parts and tools References For further instructions for maintaining MicroCal VP Capillary DSC system refer to MicroCal VP Capillary DSC System Replacing the valve needle seal Preventive Maintenance parts kit KIT190050 Cleaning instruction 28 9897 40 Replacing the syringe plunger Simple hand tools and common laboratory glassware and Replacing the syringe reagents System verification MicroCal VP Capillary DSC RNase Test Kit 28429062 Cell cleaning 2096 Contrad 70 or 1496 Decon 90 Cleaning solution 596 sodium hydroxide NaOH and a sodium hypochlorite solution NaOCl MicroCal VP Capillary DSC System User Manual 28 9887 73 Preventive maintenance GE Healthcare provides preventive maintenance service and will be happy to discuss the maintenance interval most suitable for your situation Contact your local representative or find your local contact details at www gelifesciences com contact Maintenance calendar for MicroCal VP Capillary DSC a 0 D E vo
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