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Case study : Reaction /Filtration

1. TRANSFER OUT 1 in this unit procedure In this operation you will need to specify that you are going to transfer out the cake using a specific stream the Cake stream is the only choice in this case and the transfer will be done at a certain rate 10 kg min in this case Also please specify a setup time of 20 minutes for this operation Then click OK to return to the flowsheet You have now finished initializing the operations and streams for this example process Click Save on the File menu to save your work 2 1i Simulating the Process and Viewing the Simulation Results SOLVING MASS AND ENERGY BALANCES At this point you can click Solve M amp E Balances on the Tasks menu to perform the simulation This will cause the program to perform the mass and energy balances for the entire process estimate the sizes of all pieces of equipment that are in Design Mode and model the scheduling of each piece of equipment As a shortcut for performing simulations you may hit Ctri 3 or F9 or simply click Solve ME Balances on the Main toolbar VIEWING SIMULATION RESULTS The following simulation results can then be viewed for this example Stream Data The calculated flowrates and compositions of intermediate and output streams can be viewed by revisiting the corresponding simulation data dialog windows double click on any stream line to see its simulation data dialog Procedure Data The procedure start time end time a
2. heptane in the box above the list see Figure 2 3 and the database will automatically scroll to the correct location Next click Register 3 to add Heptane to the list of registered pure components for this process model Alternatively you may double click on Heptane in the database listing and it will be added to your list of registered components If a component is not available in the existing component libraries you can click New 4 on the Registered Pure Components toolbar to create a new component for your process model This will be automatically added to the list of registered components For this process you will need to create components A B and C These components will represent the reactants and products of a simple reaction To create component A click New 4 and in the New Component Definition dialog that appears see Figure 2 4 fill in the letter A for the Name field Notice that as you type the contents of the Name field are automatically copied to all other fields CAS Number Trade Name Local Name Formula and Company ID etc You Just need to have something written in each of these six fields The Local Name is w As far as the program is concerned you do not need to have correct CAS Numbers Formulas the one that appears in the reports and all the input output dialog windows of the program Notice that
3. tab allows you to specify information for a detailed calculation of laboratory quality control and quality assurance expenses for more details see Chapter 9 Economics After you are done click OK to apply the changes made to this dialog and return to the flowsheet ECONOMIC EVALUATION FACTORS AT THE PROCESS LEVEL Finally there are parameters at the process level that affect the results of project economic evaluation These are specified through the Economic Evaluation Parameters for Entire Project dialog This dialog box is brought up by selecting Process Options gt Economic Evaluation Parameters on the Edit menu or you can right click on the flowsheet to bring up its context menu and select Economic Evaluation Parameters In the Time Valuation tab see Figure 2 38 of this dialog the user can specify various time Time Valuation Financing Production Level Misc Time Pararneters Year of Analysis Eile Year Construction Starts 2009 Construction Period 30 months Startup Period 4 months Project Lifetime 15 MEIE Inflation to update equip cost 400 NPY Interest Low 700 Medium 500 Hih 77 00 Figure 2 38 Adjusting the economic evaluation parameters at the process level parameters as well as the interest levels for calculating the net present value NPV of the project In the Financing tab of the above dialog the user
4. 1 View the equipment purchase cost for each process step To do that right click on a desired unit procedure icon select Equipment Data on the context menu of that procedure and in the Equipment Data dialog that appears switch to the Purchase Cost tab Remember that the displayed purchase cost is for a single piece of equipment If the requirements to carry out the specific processing task are such that more than one equipment item of the same size is needed the total cost is the indicated cost times the number of equipment items The number of equipment items is displayed on the first tab of the Equipment Data dialog 2 Select Executive Summary on the View menu to view summary economic analysis results for the entire project Please view the contents of the Executive Summary dialog for your example process now The corresponding Summary tab in that dialog should look similar to Figure 2 39 shown below 3 To view the detailed results which were used to produce the Executive Summary you will need to generate the Economic Evaluation Report EER To generate and view this report select Economic Evaluation EER on the Reports menu Any report can be created in different file formats You can set the format and many other settings from the dialog that comes up if you select Options on the Reports menu The EER contains an executive summary that presents the key analysis results a breakdown of the total capital co
5. 0 f Fixed independent of year of analysis O For Reference Year 2009 O User Defined Cost Model Parameters Figure 2 35 The Purchase Cost tab of the Equipment Data dialog Adjustments Now please click on the Adjustments tab of this dialog to view the number of standby units the material installation and maintenance cost factors the percentage of purchase cost that is already depreciated and the usage and availability rates for the batch reactor The fields on this tab are described in detail below Number of Standby Units For pieces of equipment that are critical to the operation of a process you may choose to have one or more standby units in case the regularly used pieces of equipment go down for scheduled or unscheduled maintenance The number of standby units affects the capital investment but has no impact on maintenance and labor cost Material Factor The purchase cost that is estimated using the built in model corresponds to a certain material of construction that is displayed on this tab Selecting a different material will affect the equipment purchase cost The material cost factors for each type of equipment can be viewed by selecting Equipment Materials on the Databanks menu Additional materials and material factors can be added to the User database Installation Cost Factor This factor is used to estimate the installation cost for each piece of equipment as a fraction of their p
6. 2 Initialize the process model using the following items of the Tasks menu a set the plant operation mode batch or continuous using item Set Mode of Operation b register pure components using item Pure Components gt Register Edit View Properties and stock mixtures using item Stock Mixtures gt Register Edit View Properties and c if the plant operation mode is batch specify recipe scheduling information using item Recipe Scheduling Information You may also want to change the default physical units of the process model using item Process Options gt Physical Units Options on the Edit menu 3 Build the process flowsheet by adding unit procedures from the Unit Procedures menu while in Select Mode x Switch to Connect Mode 3 to draw streams and connect the unit procedures 4 Add operations such as Charge Agitation Batch Heating Batch Stoichiometric Reaction etc to unit procedures Different unit procedures have different operations available to them Batch semi continuous cyclical unit procedures can contain one or more operations whereas continuous unit procedures are equivalent to unit operations After the desired operations have been added initialize all operations and streams 5 Complete the analysis of the process model using the following commands a solve mass and energy balances and size equipment by clicking Solve M amp E Balances on the the Main toolbar or on the Tasks menu b classify stream
7. component After the simulation please remember to visit the simulation data dialog of stream S 104 and check the amount of emitted Heptane Note that for particulate and other components for which emission models are not available the user can specify directly the emission percentage For this operation leave all the default values for the Volumes Labor etc and Scheduling tabs Next click OK Next Operation gt on the simulation data dialog to move to the second Charge operation named Charge React A in this unit procedure For this operation use stream S 102 to add 50 kg of material A to the reactor please remember to visit the stream s simulation data dialog and add material A to the stream Also specify a 5 minute setup time and a 20 kg min charge rate Keep the default values for the other tabs Then click OK Next Operation again to move to the final Charge operation named Charge React B For this operation use stream S 103 to add 40 kg of material B Also change the setup time to 5 minutes and the charge rate to 20 kg min Click OK Next Operation once more to move to the Batch Stoichiometric Reaction operation named React Notice that the Oper Cond s tab is different for this operation than it was for the charge operations Also two additional tabs are present These include a Fed Batch tab that contains available specification opti
8. e Ba Bea T a FH AEJ ak P fl Boa Mf Mainbranch vv Bl ae ha Waiting for Simulation to Start an F 2 PFF 101 PAF Filtration P 1 101 Wessel Procedure GethngStart For Help press F1 Figure 2 8 The example process flowsheet with streams added Tutorial 2 15 Developing a Process Model Changing the Appearance of Streams When SuperPro Designer is in Select Mode and the mouse pointer is over a stream line it changes to a menu pointer Rg to indicate the availability of a stream context menu see Figure 2 9 This menu can also be displayed by right clicking on a stream line Simulation Data Copy Contents Initialization Options Edit Tag Mame Edit Elbows Order i Style Incl In Stream Report Help F1 Figure 2 9 The stream context menu Through the stream context menu you can view or edit in case of input streams the composition flowrate and other stream properties using item Simulation Data select different stream initialization options using item Initialization Options change the tag name label of the stream using item Edit Tag Name adjust the elbows of the stream line using item Edit Elbows edit the stream style e g label and line color line thickness etc using item Edit Style etc Note that double clicking on a stream line is equivalent to clicking Simulation Data on the stream s co
9. Charge React A 0 o 0 Charee React A 0 12 W Charge React B i 0 Charee React B 0 12 h React i EE 600 Transfer to PFF 101 6 P s Teansfex to PFF 101 3 00 h EP 2 in PFF 101 6 E FILTERA 6 D FILTER 3 00 h CAKE WASH 1 lo 9 I CAKE WASH 1 0 50 h TRANSFER OUT 1 10 TRANSFER OUT 1 0 47 h For Help press F1 Figure 2 27 The Operations Gantt Chart for a single batch The Equipment Gantt Chart interface is similar to that of the Operations Gantt Chart Please generate the Equipment Gantt Chart for your example process and for a single batch now by clicking Gantt Charts gt Equipment GC on the Tasks menu In this chart the elementary TUTORIAL Developing a Process Model activity corresponds to the time frame that an equipment is kept busy by an operation during a procedure cycle In this example activity summaries are shown for unit procedures corresponding to the time frame that an equipment is kept busy by a procedure for equipment corresponding to the time frame that an equipment is kept busy by all procedures it hosts and for the complete recipe named total occupation time In addition to displaying scheduling information Gantt Chart interfaces also present you with a graphical way to modify scheduling parameters for an activity and immediately visualize the effects on the entire batch production In fact anything you can accomplish wit
10. Developing a Process Model aqua line corresponds to the supply rate of material A The increases in inventory indicate the replenishment schedule suggested by SuperPro Designer To explain this further let us focus first on the first batch cycle Please click the Show Chart at Nominal Size button and then the Zoom To button on the chart s toolbar and check the Day option The chart will zoom to one day Notice that the supply of fresh material starts right away since the opening inventory 100 kg is less than 85 of storage capacity 255 kg The inventory amount increases linearly up to the point that a charge of material starts as part of operation Charge React A During charge 50 kg of material are being charged and at the same time fresh material is being supplied at a lower rate which results in a linear decrease in inventory amount Afterwards the inventory amount increases linearly again until it reaches the 85 limit which triggers material supply off The inventory amount remains at the same level until new material is charged In subsequent batch cycles every time material is charged the inventory amount falls by 50 kg This leaves 55 kg in the beginning of the sixth batch cycle During charge in that cycle the inventory amount reaches 10 of storage capacity 30 kg which triggers the supply of fresh material on while the charge of material is on going This results in a linear decrease in the inventory amount during ch
11. Feed streams do not have a source unit procedure and in batch processing they are mainly utilized by charge operations Intermediate streams connect two unit procedures and they are used to transfer material from the source to the destination unit procedure Product streams do not have a destination unit procedure All streams are automatically identified with a stream tag In order to add streams to the flowsheet you must first click Connect Mode 71 on the Main toolbar When you do this and return to the flowsheet the mouse pointer changes to the add stream pointer Ras to indicate that you are in Connect Mode as opposed to Select Mode Then you can add feed intermediate and product streams as described below gt To Add a Feed Stream 1 Click on an empty area in the flowsheet to initiate drawing of the stream Notice that as you move the mouse pointer over the inlet and outlet ports it changes to a port pointer Qe 2 Move the mouse pointer over the desired inlet port of the destination unit procedure and once the port pointer is displayed click on the port to terminate the stream line SuperPro Designer automatically draws the feed stream symbol at the beginning of the stream and labels the stream gt To Add an Intermediate Stream 1 Move the mouse pointer over the desired outlet port of the source unit procedure and once the port pointer is displayed click on the port to initiate d
12. J to open the simulation data dialog for the wash in stream Add pure component Heptane to the stream and click OK to return to the operating conditions tab Notice that you can choose among three specification options for the volume of wash to use e Available In Wash In Stream e Volume per Cycle per Unit or e Volume per Cake Volume If the first option is selected the program will use the amount that is available in the wash in stream as the wash amount Therefore you must specify the mass or volume of the wash in stream through the stream s simulation data dialog Alternatively you can select the second TUTORIAL Developing a Process Model option and specify the volume of wash to use per procedure cycle and per equipment unit directly or select the third option and specify the specific volume of wash with respect to the cake volume For this example please keep the third option which is the default one and change the value of the volume per cake volume to one Keep the default values for the wash time 30 minutes and the wash flux 200 L m h and change the wash type from Displacement to Slurry A slurry wash will essentially dilute the soluble components trapped in the cake and remove most of them in the wash stream whereas a displacement wash will remove the soluble components from the cake in a plug flow fashion Finally click OK Next Operation to initialize the Transfer Out operation named
13. calculations equipment size and number of units may affect the material and energy balances the process time etc Switching to Rating Mode may also affect the interface of some operations of that procedure To experience this please select Rating Mode for Plate amp Frame Filter PFF 101 change the size of the filter to 4 m and click OK to return to the flowsheet Then revisit the dialog of the filtration operation In this case you need to specify either the filtration time or the average filtration flux remember that in Design Mode you must specify both Please set the filtrate flux to 150 L m h and redo the mass amp energy balance calculations This will calculate a new filtration time see Figure 2 24 In general most batch operations have the capability of calculating their cycle time when the equipment size is specified Rating Mode Through the Equipment tab you can also select the specific piece of equipment that is going to carry out the processing step By default it is assumed that each unit procedure is carried out in its own exclusive equipment However two or more different unit procedures can share equipment if they are in batch operating mode and the entire process is also in batch mode For more information on equipment sharing see 6 1b Equipment Selection amp Sharing and the two detailed examples that follow 2 2 The Synthetic Pharmaceutical Process and 2 3 The b Galactosidase
14. continuous cyclical unit procedures can contain one or more operations whereas continuous unit procedures are equivalent to unit operations To add a unit procedure to the flowsheet first select the desired unit procedure from the Unit Procedures menu For our example please select Batch Vessel Procedure gt ina Reactor Notice that after you select a unit procedure and move the mouse pointer to the flowsheet area it changes to the add step pointer aus This indicates that your next mouse TUTORIAL Developing a Process Model click on the flowsheet will lay down the icon of the selected unit procedure in that location Please click near the left side of the flowsheet to lay down the icon of the selected unit procedure SuperPro Designer automatically adds a default procedure name P 1 host equipment name V 101 and procedure description Vessel Procedure below the icon After you have added a Batch Vessel Procedure in a Reactor to the flowsheet please add a Plate and Frame Filtration Procedure by clicking Filtration gt Plate and Frame Filtration on the Unit Procedures menu and then clicking somewhere to the right of the vessel procedure icon Your flowsheet should now look something like this SuperPro Designer GettineStarted3_Oal Sele El File Edit Unit Procedures Tasks Charts View Reports Databanks Window Help x in sia A kja BS a2GuaeR av ka 38 i 2 Py Main Brancn v F ie A r
15. etc that are used once and thrown away belong to this category too Parameters related to consumables are specified through the Consumables tab of the Equipment Data dialog SuperPro Designer features a Consumables databank as part of the User database where users can store information for all the consumables that they utilize The information in the Consumables databank is accessible through the Consumables tab of an equipment ECONOMIC PARAMETERS AT THE SECTION LEVEL Division of a process into sections facilitates reporting of results for economic evaluation raw material requirements and throughput analysis of integrated processes A process section is a group of unit procedures that have something in common All processes initially contain one section called the Main Section by default For information on how to create process sections and edit their properties see 2 2b Specifying Process Sections Section level Capital Investment Factors SuperPro Designer uses a factor based method to estimate the capital investment associated with each section of a process These factors have been assigned default values that should be reasonable for most cases However you should still check these factors to ensure that they are accurate for your situation You can then adjust the factors to better suit your particular process file Figure 2 36 shows the DFC tab of a section s Capital Cost Adjustments dialog T
16. made from each stream s dialog This choice overwrites the default choices of physical units for the whole process as specified by selecting Process Options gt Physical Units Options on the Edit menu 6 The Environmental Properties tab of a stream s simulation data dialog displays the concentrations and daily throughputs of the environmental and aqueous properties of the stream TOC CaCO3 TP TKN COD ThOD BOD5 BODu etc All values are for display only and cannot be edited by the user through this dialog box However the environmental properties of the pure components contained in that stream which contribute to the above stream properties can be edited by selecting Pure Components gt Register Edit View Properties on the Tasks menu To edit the environmental properties of a pure component double click on the desired component in the list of registered pure components and in the dialog that comes up click the Aqueous tab For more details on streams and their properties see Chapter 4 Streams After you have specified the composition of the Heptane stream click OK to return to the operating conditions tab for the Charge Solvent operation Then specify the amount of material that is going to be charged 800 kg Notice that there are several ways that the duration of this operation can be specified For this example change the setup time of your charge to 5 minutes and set the volumetric flowrate to 10
17. 0 kKwime Max Cake Thickness 75 00 om SetTotalPower 00000 kw H Cake Thickness 0 00 cm O Set Power per Unit 0 0000 EZ Figure 2 20 The Oper Cond s tab for Cloth Filtration operation FILTER 1 in procedure P 2 Start Time Duration Start Time Shift 0 00 h Setup Time l0 00 min Process Timef3 00 h O Relative to the Beginning of the Batch Turnaround Time 0 00 min 50 PEE LLELE F feet Pe et las jn n a cin tan TE aS oe i m jt Re tt J piegi hy piiienri gg LEON piii y ii Pnt Pria ap be none 3 e AER i nrg Relative to Another Operation in this Procedure none e Number of Cycles 1 i i O Er Absolute Start Time 6 25 h Relative to Another Operation in Another Procedure Hoedt EE Ik Procedure P fin 107 Operation Transfer to PFF 101 Start End Figure 2 21 The Scheduling tab for Cloth Filtration operation FILTER 1 in procedure P 2 Tutorial 2 29 Developing a Process Model 2 30 Tutorial Next please visit the Scheduling tab of the filtration operation This tab is common to all operations in batch unit procedures By default the first operation in any batch unit procedure is scheduled to start relative to the beginning of the batch In order to accurately schedule your filtration you will need to change the start time to be relative to the start of the Transfer Out operation Transfer to PFF 101 in procedure P 1 see F
18. 0 L min so that your tab looks like the one shown in Figure 2 14 To enter a new value in different units than the ones selected you must first change the units prior to entering the new value This is necessary since the units selection list acts as a unit converter and changing the units will automatically convert the existing value to the selected units Please also visit the Volumes Vent Emissions Labor etc and Scheduling tabs to see what they contain A brief description of each of these tabs follows e Volumes tab Through this tab the user can specify the maximum and minimum allowable working vessel volume for this operation 1 e by the end of the charge operation the vessel should not be more than 90 full In Design Mode this is taken into account for sizing the equipment In Rating Mode the program makes sure that a vessel is not overfilled or the level does not drop below the agitator level e Vent Emissions tab Through this tab the user can specify which volatile organic compounds VOCs will be emitted whether a sweep gas will be used for emissions associated with reaction and crystallization operations and what temperature the vent TUTORIAL Developing a Process Model condenser should be set at SuperPro Designer is equipped with VOC emission models that are accepted by EPA For more details see Chapter 10 Emissions Labor etc tab Through this tab the us
19. 36 Tutorial TUTORIAL Developing a Process Model The material of this paragraph is only relevant to process flowsheets that include recycle loops To see an example of a recycle loop please open file Bgal8_Ob that can be found in the Examples Bgal directory of SuperPro Designer In this file streams S 102 and S 108 are part of a recycle loop For a description of this file see2 3 The b Galactosidase Process SuperPro Designer s default convergence parameters for flowsheets that include loops which result in iterative calculations have been tuned in order to be adequate for most situations However occasionally especially in cases involving highly non linear models they may fail to converge In these cases you may fine tune the convergence characteristics for a particular application To change the convergence parameters for the process with loops click Process Options gt Recycle Loop amp Tear Stream Options on the Edit menu Alternatively right click on the flowsheet and click Recycle Loop amp Tear Stream Options on the flowsheet s context menu This will bring up the Recycle Loop and Tear Stream Options dialog of Figure pay Below is a list of actions that you can take to improve the system s performance in converging iterative calculations ls Adjust the convergence tolerance Relative Tolerance for stream total or component mass flow and optionally temperature The convergence tolerance is de
20. ANKS SuperPro Designer provides for the use of multiple component databanks The following component databanks can be used e the Designer databank e the User databank and e the DIPPR databank TUTORIAL Developing a Process Model Each databank is contained in a separate database file The Designer databank is part of the Designer or System database It provides data for over 530 commonly used compounds The User databank is part of the User database an it is a repository available for users to store data for their own or user defined components The User component databank is originally upon installation of the software empty The DIPPR databank draws its data from the relational form of the DIPPR database This component database has been developed and maintained at Brigham Young University A demo version of the DIPPR databank with only 5 components is shipped with SuperPro Designer To change the location of the database files where each of the above databanks is stored click Availability Passwords and Locations on the Databanks menu to display the Databases Availability Passwords and Locations dialog For example if the full DIPPR databank is available or if you want to use a different user database file that somebody else created you must specify its location through that dialog for more details see 15 1 Database Registration REGISTERING COMPONENTS All th
21. O Single Component in Stream 5 109 Raw Material 0 360000 kg lc Flow Reference Units kg Quick Reference Symbol MP Jf OK x Cancel 2 Help Figure 2 34 The Stream Classification dialog In this example process please classify the output streams and set costs for the two liquid waste streams as shown in Figure 2 34 First specify that the Cake stream is a revenue stream Notice that the Selling Price of a revenue stream is calculated automatically based on the stream s composition recall that there is still heptane and small amounts of impurities in our product cake so the price per kg of cake is less than the 300 kg price of pure component C TUTORIAL Developing a Process Model Next classify the two liquid waste streams as aqueous waste Check the Set By User options next to the emission stream and the two liquid waste streams and type in a value of 0 10 kg for the Disposal Cost of each Finally select the Cake stream as the Main Product Revenue stream from the corresponding drop down list and specify that the unit cost for this process will be reported based on the component flow of product C Note that the classification of a stream as a solid waste aqueous waste organic waste or an emission will cause it to be reported in dedicated sections of the Environmental Impact Report where a detailed bookkeeping is kept on all chemicals that end up in
22. Process At this point you have completed the basic initialization steps for the streams operations and equipment As you become more familiar with SuperPro Designer it will take much less time to do these activities For instance all the steps that we have done thus far in this section could Tutorial 2 33 Developing a Process Model 2 34 Tutorial be performed in about 15 minutes if you were already familiar with how to use SuperPro Designer Oper Cond s Labor etc Description Batch Sheet Scheduling Particulate Component Removal Duration Component 8 Removed Les Setup Time 0 00 min Filtration Time O Set by User FLERE m Heptane Calculated Based on Nitrogen Filtrate Flus 150 000 L me h Oeygeri Water Filtrate Stream Out 3 5 107 Cake Dryness l Power Consumption Q LoD 50 Power Type Cake Poosiy ER wy a Spesie Poue ood WZ Max Cake Thickness 15 00 em J See a Cra k Cake Thickness 237 m Set Power per Unit 0 0000 kw Figure 2 24 The Oper Cond s tab for Cloth Filtration operation FILTER 1 in procedure P 2 when the equipment is in Rating Mode Important note about building and initializing large process flowsheets when you attempt to simulate complex processes keep in mind that you do
23. TUTORIAL Developing a Process Model Case study Reaction Filtration t Tip iD PAF Fiirahon Wepre Procedure DEVELOPING A PROCESS MODEL The first example of this chapter demonstrates the key initialization and analysis steps for modeling a process with SuperPro Designer The fundamental steps and analysis features used in this example are the same as the steps and features that would be used during the creation of any other type of process Therefore regardless of which type of process you intend to model reading through the following example should provide you with the knowledge required to model processes on your own In addition since this example is a batch process it serves as a medium for discussing several scheduling issues The following files are available for this example in the Examples Misc directory of SuperPro Designer 1 GettingStartedS_Oa This file represents a simple batch process consisting of a reaction step Batch Vessel Procedure in a Reactor and a filtration step Plate and Frame Filtration Procedure The mass and energy balances for this process model are solved in equipment Design Mode in order to determine equipment sizing parameters The development and solution of this process model are described in sections 2 1b Starting a New Process File up to 2 11 Simulating the Process and Viewing the Simulation Results Furthermore the specification and analysis of scheduling equipment utilizat
24. a Gantt Chart These charts can be generated either for a single batch or for multiple batches using dedicated items on the Tasks gt Gantt Charts menu Note that this menu is only available if the plant operation mode is batch see 2 1c Specifying the Mode of Operation for the Entire Plant Please generate the Operations Gantt Chart for your example process and for a single batch by selecting Gantt Charts Operations GC on the Tasks menu It should look similar to Figure 2 27 below The left view spreadsheet view displays the name duration start time and end time for each activity participating in the overall scheduling and execution of the recipe This can be either an elementary activity or an activity summary In the Operations Gantt Chart an elementary activity corresponds to an operation executed during a single procedure cycle For this example activity summaries are shown for unit procedures and for the complete recipe You can expand or collapse activity summaries by clicking on the or signs in the boxes to the left of activity names The right view chart view displays a bar for each activity whose horizontal position and length indicate the start time and duration respectively of that activity E Operations Gantt Chart Single Batch File Edit Update Chart View Preferences Duration Start Time End Time h h h E Complete Recipe 10 49 EAP 1 in 101 9 Charge Solvent 0 0 Charge Solvent 0 28 h
25. arge in the sixth batch cycle please scroll down to the 3rd day to observe this Afterwards the inventory amount increases linearly again until it reaches 85 of storage capacity and material supply is triggered off again The above replenishment schedule is repeated every sixth batch cycle E A Inventory as Ingredient in Mixtures Multiple 12 Batches Sy Ul SSE of e 3 2 Sa n n 2 Figure 2 31 The inventory profile of pure component A in the example Note that you can see the exact time and value of a point in a line by placing the mouse pointer over that point By default the inventory graph displays the inventory amount and the supply rate To change the contents variables displayed and style e g color thickness etc of the graph right click on the chart to bring up its context menu and click Edit Style Through other context menu commands you can print a chart export a chart as a Windows Metafile wmf Tutorial 2 45 Developing a Process Model 2 46 Tutorial or export chart data into a file in Excel format with a discretization time interval that can be specified by the user This is a useful feature if you wish to combine demands for a certain resource from multiple flowsheets in Excel 2 11 Throughput Analysis and Debottlenecking SuperPro Designer is equipped with powerful throughput analysis and debottlenecking capabilities The objective of these features is to all
26. at are inherently continuous when these are added to the process e g the Centrifugal Pumping unit procedure will contain a Centrifugal Pumping operation In order to add operations to a unit procedure that is operated in batch semi continuous mode you can either e double click on a unit procedure icon or e right click on the unit procedure icon and select Add gt Remove Operations from the context menu of that unit procedure Note that this menu item is only available for unit procedures that are operated in batch semi continuous mode Either action will bring up the Operation Sequence dialog see Figure 2 13 for the selected unit procedure Double clicking on a continuous unit procedure e g a Centrifugal Pumping unit procedure added to a continuous process plant brings up the dialog window of its operation instead of the Operation Sequence dialog Essentially a unit procedure that is operated in continuous mode behaves like a single operation At this point please open the Operation Sequence dialog for the vessel procedure P 1 in the example Add a Charge operation to the operation sequence for this unit procedure by double clicking this item in the list of available operations Alternatively you can highlight this item and click Add to add the new operation at the end of the operation sequence or Insert to insert the new operation before the highlighted operation in the operation sequenc
27. at the bottom of this dialog you can choose to initialize the properties of the new component by copying them from some other database component or registered component For this example click OK to copy the properties of component Water which is available in the Designer database to component A W New Component Definition Mame g unique CAS Humber fA Trade Mame Pa Local Name iA sss unique Formula Booo Company ID A Source for Default Property Values Component Name water Location In Database Designer O List of Registered Components Figure 2 4 The New Component Definition dialog box After you have added component A to your list of registered components follow the same steps to add components B and C When you have completed this you should edit some of 2 8 Tutorial TUTORIAL Developing a Process Model the properties of these components To access the properties of component A double click on the component in the list of registered pure components Alternatively you can highlight the component by clicking on it and then click Properties 3 on the Registered Pure Components toolbar This will bring up the Pure Component Properties dialog box for component A Through this dialog you can view or edit a component s physical and environmental properties cost data and regulatory information For the pur
28. aterial and energy balance calculations they do not affect output stream temperatures They are only considered in costing and economic evaluation calculations Auxiliary utilities offer a convenient way to associate utility consumption with generic boxes and other operations that do not calculate utility demand ECONOMIC PARAMETERS AT THE EQUIPMENT LEVEL All equipment resources have two common dialog tabs through which the user can provide information that affects the capital investment and certain operating cost items Information about equipment purchase costs and various adjustments can be provided through the Purchase Cost and Adjustments tabs of the Equipment Data dialog Tutorial 2 49 Developing a Process Model 2 50 Tutorial Equipment Purchase Cost Figure 2 35 shows the Purchase Cost tab for Stirred Reactor CSTR V 101 in the example To view this tab right click on vessel procedure P 1 and select Equipment Data on the context menu of that procedure By default SuperPro Designer uses a built in model to estimate purchase costs for each piece of equipment However you can override this estimate by either using your own model or specifying an exact purchase cost from a vendor quote for instance Equipment Purchase Cost Adjustments Consumables Scheduling Throng Purchase Cost 537000 adjusted for year of analysis 2005 Cost Estimation Options SetbyUser
29. below gt To Apply the Style of a Stream to Several Other Streams 1 Right click on the source stream line e g the Heptane stream in the example and click Style gt Pickup Style 2 Right click on the desired target stream line s e g the Cake and S 105 streams in the example and click Style gt Apply Style After applying these changes your streams should look something like this SuperPro Designer GettineStarted3_Oa_formatted ef File Edit Unit Procedures Tasks Charts View Reports Databanks Window Help it sia Bika BS 2au Sv 2 fl Bia BZ Mainsrancn Yd ie A r waiting for Simulation to Start B 1 Heptane P 2 PFF 101 PZF Filtration P 1 101 essel Procedure Sg s ES a GettingStart Document was successfully saved on disk Figure 2 11 The example process flowsheet after the names and styles of streams have been changed For more information on stream drawing see 4 10 Classification of Input and Output Streams Tutorial 2 17 Developing a Process Model 2 18 Tutorial 2 1h Initializing Unit Procedures SPECIFYING THE OPERATING MODE OF UNIT PROCEDURES Each unit procedure added to the process has its own operating mode setting This can be either e batch semi continuous or e continuous Batch semi continuous cyclical unit procedures can contain one or more operations whereas continuous unit procedures are equivalent to unit operations T
30. bring up its context menu and select Edit Style Through context menu commands you can also print a chart export a chart as a Windows Metafile wmf or export its data into a file in Excel format with a discretization time interval that can be specified by the user This is a useful feature if you wish to combine demands for a certain resource from multiple process files in Excel Please refer to the synthetic pharmaceutical example see Figure 2 51 and the B Galactosidase example see Figure 2 63 to see resource demand charts for more complex processes Tutorial 2 43 Developing a Process Model 2 44 Tutorial RESOURCE INVENTORY CHARTS SuperPro Designer can also analyze and display inventory information for material resources Recall that 50 kg of material A are used in each batch Suppose that there is a 300kg storage capacity for A and an opening inventory of 100kg Suppose further that the loading rate of material A into storage is 200 kg h How often should shipments of A be scheduled Please select Materials gt Entering Inventory gt Multiple Batches on the Charts menu Select pure component A from the pure components drop down list box and click the Supply Info button This will bring up the Resource Inventory Data dialog for the selected ingredient Fill out the dialog as shown in Figure 2 30 This will tell SuperPro Designer that the supply of material A should be replenished when the inven
31. c Misc js Direct Fixed Capital DFC 7 77 thous DFE Estimation O ptions O Set by User PC Listed Equipment Puchase Cost Unlisted Equipment Purchase Cost Unlisted Equipment Purchase Cost 0 20 PE FPC Factor Options O Using a Composite PC Factor DFC 400 PC Using a Distributed Set of PC Factors Direct Fired Capital DFC Direct Cost DC Indirect Cost IC 0 ther Cost OC Direct Cost DC Hise tale Gata 7 Indirect Cost IC ads Bee cues Piping 4 0 35 x PC poet Instrumentation E1040 PC Engineering H 0 25 DC Insulation C 0 03 PC Electrical Facilities C 010 FC Buildings E 0 45 PC Yard Improvement F 0 15 FE Auriliary Facilities G 0 40 PC Construction l 0 25 OC Installation Installation of Listed Equip Other Cost OC dae pee ee Installation of Unlisted Equip Unlisted E quip m50 s Unlisted Equip PC Contractors Fee 0 05 DC IC Ingtallatian Cost DC F Installation 4 6 C 0 E F G Contingency 0710 DC IC Figure 2 36 Adjusting the capital cost parameters at the section level 2 52 Tutorial TUTORIAL Developing a Process Model Section level Operating Cost Factors SuperPro Designer calculates and reports nine cost items for each process section Materials Labor Dependent Facility Dependent Laboratory QC QA Consumables Waste Treatment Disposal Utilities Transportation and Miscellaneous Costs Figure 2 37 display
32. can provide information on the financing of the project e g equity versus borrowed money for DFC working capital etc the method of TUTORIAL Developing a Process Model depreciation the depreciation period the salvage value and the DFC outlay the spending of direct fixed capital as a function of time In the Production Level tab of the above dialog the user can specify the capacity utilization profile production level for the expected lifetime of the project and provide information for product failure rate and disposal cost of scrapped product Please note that the production level only affects the Cash Flow Analysis calculations It has no impact on other project economic evaluation variables In the Miscellaneous tab of the above dialog the user can provide information for estimating income tax advertising and selling expenses and running royalties For the definitions of the different economic factors and for a description of how these are calculated please consult Chapter 9 Economics PERFORMING ECONOMIC CALCULATIONS AND VIEWING THE RESULTS After simulating the process you can carry out the economic calculations by clicking Perform Economic Calculations on the Tasks menu The same can be accomplished by clicking Perform Economic Calculations on the Main toolbar or pressing Shift F9 hold down the Shift key and hit the F9 key on your keyboard Depending on your interest you may then do the following
33. cedure equipment or operation to inspect or even modify values of operating conditions If you modify the values of streams and or operations belonging to unit procedures that have already been solved 1 e the check mark icon appears underneath or to the unit procedure that is currently being solved but the operation whose values have been modified has already been solved then the new values will not be taken into account until the next Solve M amp E Balances command is issued CONVERGENCE OF RECYCLE LOOPS E Recycle Loop amp Tear Stream Options Wegstein Acceleration Stream Convergence Criterion O No Successive Substitution Max No Iterations 00 Flow Converge Based On O Component Flowrate Estimated Total Stream Flowrate q Min 5 00 Relative Tolerance 000m0 T gq Mas 500 Set by User Ed Apply Temperature Convergence Relative Tolerance ooo 000000 q 0 00 linew old clel 00010000000 new old old Tear Stream Options Reset Tear Stream Flows to Zero Reset All Stream Flows on a Loop to Zero X Reset Temperature amp Pressure when Reseting Flows Show Tear Streams on Flowsheet wf OF Tear Stream Search Algorithm x Search for Non Redundant Tear Sets First Explore Best Candidate Streams Only Record Failed Choices Figure 2 25 Adjusting the convergence parameters in a process that includes recycle loops 2
34. cess Model e Calculated Design Mode and e Set by User Rating Mode These options can be specified through the Equipment tab of the corresponding Equipment Data dialog By default all equipment resources start in Design Mode In this mode SuperPro Designer will determine the required number and size of equipment units based on operating conditions and performance requirements Usually there are physical limitations on the available size of processing equipment For example a Plate amp Frame Filter may not be available with a cloth area greater than 80 m When you are in Design Mode you must specify the maximum available size for the equipment involved e g the Max Filter Area for the Plate amp Frame Filter If the calculated equipment size exceeds the maximum allowable size SuperPro Designer will employ multiple pieces of equipment sized equally with sizes that do not violate the maximum available size For your example process a filter size of roughly 2 m should have been calculated as shown in Figure 2 23 see also file GettingStarted8_Oa in subdirectory Examples Misc This number was calculated from the volume of material that was processed per cycle the filtrate flux and the filtration time If you change the equipment sizing method to Rating Mode you can specify the size and number of units SuperPro Designer will then take this information into account in the simulation
35. con to the selection click on it while holding down the Ctrl key To remove an icon from the selection Ctrl Click on it again To select an entire flowsheet click Select All on the File menu or press Ctri A gt To Move Unit Procedures 1 Select the desired unit procedure icon s 2 Drag the selected icon s to the new location If multiple icons are selected you can drag any member of the selection and all icons will move simultaneously You can use the arrow keys to move the selection one pixel at a time Note that when you move a unit procedure icon that has streams attached to it all streams will move with it If two unit procedures are connected through an intermediate stream and both the source and destination unit procedures move then the stream will keep its structure intact and move with them If one of the stream s ends remains anchored while the other end is being moved then the stream will adjust its first and or last elbow to accommodate the change of location for more details on streams see Adding Streams on page 2 14 gt To Delete Unit Procedures 1 Select the desired unit procedure icon s 2 Hit the Delete key on your keyboard or click Clear on the Edit menu The selected unit procedure s will be erased When you delete a unit procedure all streams attached to it will also be deleted gt To Cut or Copy and Paste Unit Procedures SuperPro Designer allows you to cut or copy unit procedure
36. ctivity summaries of a Gantt Chart by selecting Styles gt Gantt Chart on the Preferences menu of the chart You may also use the items in the File menu of the chart to print the chart export scheduling data to MS Excel or MS Project or export the chart as a Windows Metafile wmf Note also that if you generate an Operations Gantt Chart or an Equipment Gantt Chart for multiple batches you can change the default number of batches shown on the chart by right clicking on the chart and selecting Set Number of Batches from the chart s context menu Please refer to the synthetic pharmaceutical example see Figure 2 49 and the B Galactosidase example see Figure 2 62 to see Gantt Charts for more complex processes For more information on these charts see 7 4 The Operations Gantt Chart OGC and 7 5 The Equipment Gantt Chart EGC EQUIPMENT OCCUPANCY CHARTS Another way of visualizing the execution of a batch process as a function of time is through the Equipment Occupancy Chart This chart shows in a graphical way how long each equipment is kept busy by some operation and how long it is just idle during batch processing Each chart Tutorial 2 41 Developing a Process Model 2 42 Tutorial can be generated either for a single batch or preferably for multiple batches using dedicated items on the Charts gt Equipment Occupancy menu Please generate this chart for your example process by selecting Equipment Occupancy gt Multiple Batch
37. djusting the value of q If q is between zero and 1 the procedure is a modified successive substitution if q is negative then the convergence is accelerated Switch from Wegstein acceleration to successive substitution This may slow down the convergence calculations but will increase the likelihood of convergence Select a different tear stream for a recycle loop by right clicking on a specific stream that is part of the loop and selecting Preferred Tear The current tear streams are identified on the flowsheet with two red slashes if you check the Show Tear Streams on Flowsheet option that is available in the Recycle Loop and Tear Stream Options dialog Tutorial 2 37 Developing a Process Model 2 1j Setting the Process Scheduling Information The following terms are used for batch process scheduling Term Description Annual Operating The number of hours per year the plant is devoted to making a Time AOT specific product Campaign An uninterrupted run of batches Batch Time The start to finish time for a single batch Cycle Time The time between two consecutive batch starts It is sometimes called the recipe or plant cycle time Minimum Cycle The minimum possible cycle time based on the time scheduling Time bottleneck Cycle Time Slack The difference between the actual and minimum cycle times If the process is in batch mode as is the case for your example process you should provide process sc
38. does crash there is sometimes a possibility that you will not be able to re open the file you were most recently working on In that case you should try to open the backup versions of your file Anytime you save a newer version of your file SuperPro Designer will also save a backup copy of the previous version using file extension sp as opposed to a normal spf file If the sp backup file already exists SuperPro Designer will first create a copy of that file using file extension s as a second backup To open a file click Open from the File menu This will bring up the Windows Open dialog box To open a backup file simply go to the directory where you saved your original file select the corresponding sp or s backup file select All Files in the File Type field of the dialog box and click the Open button Note that the corresponding file extensions for the original backup and second backup files in EnviroPro Designer are epf ep and e 2 1g Building the Process Flowsheet ADDING UNIT PROCEDURES The first step in building a flowsheet is to add processing steps unit procedures to the process A unit procedure is defined as a series of operations that take place within a piece of equipment The types of operations available depend on the type of unit procedure you are using As explained later in this chapter see 2 1h Initializing Unit Procedures batch semi
39. e Add Remove Operations Charge React 4 Charge J i Charge React B Charge React Babch Stoich Reaction Transfer to PFF 101 Transfer Out Procedure Data Procedure State Properties Procedure Activity Overview Equipment Data Equipment Contents Set Breakpoints Edit Labels Disconnect Order Style Help F1 Figure 2 12 The context menu of the Batch Vessel Procedure in a Reactor in the example The meaning of each item in the context menu of a unit procedure is explained below e The Operation Data item allows you to access or modify the simulation parameters of the operations that have been added to the unit procedure Note that this item is not TUTORIAL Developing a Process Model available if no operations have been added to the unit procedure If the unit procedure contains a single operation clicking on this menu item will bring up the Operation Data dialog for that operation If it contains more than one operations clicking on this menu item or simply moving the mouse pointer over it will bring up a drop down list of all added operations Clicking on an operation in that list will bring up its Operation Data dialog The Add Remove Operations item allows you to add remove operations to from the unit procedure and change the sequence in which these operations are executed This item is only available for unit pr
40. e Charge Solvent operation of this example is shown in Figure 2 14 Charge Using In 1 Heptane TEJE Scaleable X Amount Use Amount on Stream Set by User O Mass 800 000 kg O Volume 0 000 L Duration Setup Time 5 00 min Process Time Set by User 0 00 min Calculated Based on O Mass Flowrate 600 000 kg h Volumetric Flowrate 00 000 L min Set by Master Slave Relationship TE Setup Match the duration of this operation to the duration of another operation or string of operations Ignore Labor x Figure 2 14 The Oper Cond s tab for the first Charge operation Charge Solvent in procedure P 1 To initialize the operating conditions for the Charge Solvent operation you begin by selecting the charge stream for this operation Use the Charge Using drop down list at the top of the tab to select the stream which you renamed Heptane earlier in this section Then click on the View Edit Stream Composition and or Amount UHU button next to the drop down list in order to access the simulation data dialog for that stream see Figure 2 15 and specify its 2 22 Tutorial TUTORIAL Developing a Process Model composition To add Heptane to the stream double click on the corresponding item in the Registered Ingredients listing for that stream Stream Heptane INPUT gt P 1 Composition etc Physical S
41. e To delete an operation from the operation sequence click Delete x on the available toolbar If you add an operation in the wrong order you can change its position in the operation sequence using the Move Up 3 Move Down Move to Top 3 and Move to Bottom buttons on the same toolbar Notice that when the charge operation is initially named CHARGE 1 when it is added to the operation sequence Double click that item or highlight that item and click Rename A on the available toolbar and change the name of the added charge operation to Charge Solvent Now add two more Charge operations a React Stoichiometric Batch Stoichiometric Reaction operation and a Transfer Out operation to the operation sequence Rename these operations to Charge React A Charge React B React and Transfer to PFF 101 TUTORIAL Developing a Process Model respectively so that your dialog box looks like the one shown in Figure 2 13 Then click OK to return to the process flowsheet Operation Sequence for Procedure P 1 in V 101 PETET E a xK A Sh ir Charge Solvent Charge Charge React A Charge Charge React B Charge React Batch Stoich Reaction Transterto PFF 101 Transter Out Ferment Kinetic Ferment Ferfusion Ferment Stoichiometric React Equilibrium React Kinetic React Stoichiometric Sample SIF Split Compo
42. e description Vessel Procedure for the vessel procedure in this example The Disconnect item deletes all streams connected to the unit procedure The Flip reverse flow direction item allows you to change the flow direction of the unit procedure icon from left to right default to right to left and vice versa You can also do that by clicking Flip Horizontally on the Visual Objects Toolbar see 13 5 Visual Objects Toolbar Note that this option is only available when the unit procedure does not have any streams attached to it The Order item forces the unit procedure icon to appear behind or in front of other icons text etc Tutorial 2 19 Developing a Process Model 2 20 Tutorial e The Style item allows the user to edit such things as the icon color the tag name color and font etc e The Help F1 item provides access to the Help file of the unit procedure ADDING OPERATIONS TO UNIT PROCEDURES The next step toward initialization of unit procedures is to add relevant operations to each unit procedure This step is generally required for unit procedures that are operated in batch semi continuous mode For convenience some inherently batch semi continuous unit procedures may initially contain one or more operations when added to the process e g the Plate and Frame Filtration Procedure used in this example initially has a Cloth Filtration operation An equivalent operation is always added to unit procedures th
43. e components that will be used in a process model must be registered first To register components in other words to make them available in your process model select Pure Components gt Register Edit View Properties on the Tasks menu This will activate the dialog shown below E Register Edit Pure Components Pure Component Databank Registered Pure Components Source DB Designer FE e e Site e x ES he Local Name Name Source i eee A A Local Fluorabenzene Fluoroethane Phys Props B Fluoromethane gt c Heptane Enviro Props i Nitrogen Oxpgen water Heptadecane Hesachlorobenzene Display by Name Local Name Trade Name CAS Number Primary Biomass Composition Activity Calculations YOK X Cancel Z Hep Biomass Comp none ef Comp Inon SSCS E E eke Basis Strength 0 00 Uma Water Content 2000 26 wut Figure 2 3 The pure component registration dialog box Note that pure components Nitrogen Oxygen and Water are registered by default in every new process model and cannot be deleted For this example process you will need to add Tutorial 2 7 Developing a Process Model Heptane to the list of registered pure components shown on the RHS of this dialog as well To add Heptane you can either scroll down to it in the list of available pure components in the Designer database shown on the LHS of this dialog or you can begin typing
44. e help topic for the Plate and Frame Filtration Procedure Tutorial 2 13 Developing a Process Model 2 14 Tutorial dedicated to each function you can look up the desired equipment or unit procedure in the program s Help system which is available through the Help menu This provides access to supporting documentation shipped with the software such as the electronic version of the User s Manual and additional content As a shortcut to the Help menu for any unit procedure you can click Help Mf on the Main toolbar and then click on the unit procedure icon you are interested in Alternatively you can click on the unit procedure icon and hit the FI key Note that you can also use the Help KA button feature as a shortcut to access the Help files for other interface elements such as menu options toolbar buttons dialog boxes and dialog tabs At this point please open the Help file for the Plate and Frame Filtration Procedure A portion of that file is shown in Figure 2 7 Notice that dedicated ports of the host equipment Plate amp Frame Filter are labeled next to its icon The Help file for each unit procedure also contains a general description links to its operation models and to the host equipment and much more ADDING STREAMS After you add a unit procedure to the process flowsheet you can add streams There are three types of streams e feed input streams e intermediate streams and e product output streams
45. e sign indicates whether the break is on the entry left sign operations middle sign or exit right sign of the procedure Once a breakpoint is set next time the Solve M amp E Balances command is issued the simulation calculation sequence will pause at that location When the simulation sequence is paused some buttons of the Solve toolbar become active Also notice that while the simulation has been paused all unit procedure display another icon underneath that indicates the simulation state of each procedure at that time as the simulation is paused The following sequence of images indicate the state of the unit procedure that is currently being solved Image Explanation Hirtinrtititrtibtiitititiitiitibtintitittitibtititittiitititititititibtiitibtinbtidd nail Boo A break on entry has been encountered Seo A break on operation has been encountered eee A break on exit has been encountered oooe A break on entry has been encountered shown when there are operations that can auto adjust the flow of process input streams Seooe A break on material pull in has been encountered for operations that can auto adjust the flow of process input streams SOOoo A break on operation has been encountered shown when there are operations that can auto adyjust the flow of process input streams See A break on material pull out has been encountered for operations that can auto adjust the flow of process output streams
46. each waste category Specifically streams that are connected to venting ports are already classified as emission streams by default The Environmental Impact Report allows you to evaluate the burden of the process on the environment Such an assessment assists the designer to focus his her attention on the most troublesome streams and the processing steps that generate them A related report the Emissions Report EMS provides information on emissions of volatile organic compounds VOC and other regulated compounds The Emissions Report will also give information on the emitted components as well as the contributing unit procedures and operations to these emissions ADJUSTING THE COST FACTORS The user can specify economic evaluation parameters at four levels e the Operation level e the Equipment level e the process Section level and e the Process level Please note that the economic evaluation parameters from each of the three levels have a significant impact on the cost calculations Therefore the parameters at all three levels should be examined by the user and edited if necessary ECONOMIC PARAMETERS AT THE OPERATION LEVEL Parameters that affect demand for labor and utilities are specified at the operation level For instance the labor requirement for an operation can be specified through the Labor etc tab of an operation s data dialog Through the same dialog you can specify auxiliary utilities which have no impact on m
47. eeees A break on exit has been encountered shown when there are operations that can auto adjust the flow of process input streams The following sequence of images indicate the state of all other unit procedures while the simulation is paused tena anes taste EE E Gy The procedure has not been visited yet lt J The procedure has been successfully simulated already Pia The procedure s M amp E balances are being solved recursively as part of loop convergence The solution of the procedure s M amp E balances ended unsuccessfully as part of an un converged loop amp R The solution of the procedure s M amp E balances ended unsuccessfully an error was encountered Tutorial 2 35 Developing a Process Model Notes 1 You can toggle the visibility of the breakpoint icons above the unit procedure and of the state icons below the unit procedure using the Show Hide Breakpoints and Show Hide Status buttons respectively on the Simulation Control toolbar 2 To temporarily deactivate breakpoints without removing them simply visit the Breakpoints dialog of a unit procedure and click once more on the checked breakpoint location Notice how the checkmark now is still there but looks faded grayed out The breakpoint sign above the unit procedure icon will look faded as well 3 When the Solve M amp E Balances sequence is paused you may visit the simulation data dialog of any stream unit pro
48. er 12 Reports SUMMAN Capital Investment Operating Cost Revenues Credits Project Totals Investment 4541 981 Investment Charged AA to this Project 1 211102 Annual Operating Cost a a4 r Annual Revenues 315 875 r Annual Production Aate 1 052 917 kg MP yr Unit Production Cost 82 9262 kg MP Unit Production Revenue 200 0000 kg MP Project Indices Gross Margin 72 36 2 PaT i24 Payback Time OBS peal IRR atertan sis F NP at7 00 x 99 980 MF Flow of Component C in Stream Cake Figure 2 39 The Summary tab of the Executive Summary dialog for the example process 2 1n Environmental Impact SuperPro Designer generates two different reports that provide information on the environmental impact of a process The Emissions Report select Emissions EMS on the Reports menu provides information on all emitted components including volatile organic compounds VOCs and other regulated compounds The Environmental Impact Report select TUTORIAL The Synthetic Pharmaceutical Process Environmental Impact EIR on the Reports menu provides information on the amount and type of waste generated by a manufacturing facility It also provides information on the fate of a compound that enters an integrated manufacturing or waste treatment facility for more details on these reports see Chapter 12 Re
49. er can specify labor requirements and auxiliary utilities Scheduling tab The is the right most tab of all batch unit procedures Through this tab the user can specify the start time and duration for an operation Note that no scheduling information is required for unit procedures that are operated in continuous mode Depending on the complexity of an operation additional tabs may be used to display other pertinent variables For the heptane charge in your example process Charge Solvent please switch to the Vent Emissions tab and click the Venting box and then the Emissions box see Figure 2 16 By default the port that is connected to stream S 104 is selected as the venting port Oper Cond s Volumes Vent E missions Labor elc Description Batch Sheet Sched Operating Pressure 1 013 bar Went Port Stream Out 1 5 104 Auto Tag Stream X Operating Mode Open Vessel Atmospheric Pressurized Vessel with Relief Valve Set At 1 013 bar X Emissions Component Emission Data Ernitted f Set By User Heptane Nitrogen Oxygen Water E E 2 Vent Condenser C Off On at Temperature 20 00 E Figure 2 16 The Vent Emissions tab for the first Charge operation Charge Solvent in procedure P 1 Tutorial 2 25 Developing a Process Model 2 26 Tutorial Then check the Emitted box next to the Heptane
50. ered pure components which you have created or modified to the User databank so that you can register these components in other files as well To add a component to the User databank first select the databank in the Source DB drop down list Then highlight a registered component and click on the Deposit button Deposit Tutorial 2 9 Developing a Process Model 2 10 Tutorial The current version of SuperPro Designer does not make use of the Normal Freezing Point of pure components The corresponding field entry which can be found in the Physical Constant tab of the Pure Component Properties dialog can be ignored REGISTERING MIXTURES Mixtures are used to facilitate initialization of input streams in cases where certain raw materials e g buffers are consumed as mixtures In order to register a mixture click Stock Mixtures Register Edit View Properties on the Tasks menu and follow the same steps as for registering pure components 2 1f Saving and Opening Files At this point please save your file by clicking Save As from the File menu and giving your process model a descriptive name in the Windows Save As dialog box that appears In general it is a good idea to save your work often in order to avoid having to redo work in the event of a program crash When working with larger process files include the date or some other version indicator in the saved case name If the program
51. es on the Charts menu By default two batches are shown To add more right click on the chart to bring up the chart s context menu and select Set Number of Batches Please change the number of batches to three and press OK Your chart should look similar to that shown in Figure 2 28 E EEEE coors B Lauipment Occupancy Chath J Multiple 2 Batts mone X ey Zoomto v Q Zoom by v g e SEng 0s l i l i Batch Time maa h H a Min Cycle Time fags Mh H Cycle Time 4335 Mh H Cycle Time Slack 000 Mh H Number of Campaigns Y r 7 ADT Available 7920 0 Ih AOT Utilized 7916 0 h Max Batches Yr mss Actual Batches Yr M58 Longest Unit Procedure P 12 in TDR 101 Scheduling Bottleneck Equipment R 101 INFD 101 Ne Z N O 3 4 o D m i ri ao Sa a yi w A TDR 101 Figure 2 28 The Equipment Occupancy Chart for three consecutive batches For each equipment the occupancy time by some operation is represented by a bar White space represents idle time Placing the mouse pointer over a bar will display the name of the operation that corresponds to that bar Right clicking on a bar will bring up its context menu On this menu you can click Operation Data to display the Operation Data dialog for the corresponding operation or Procedure Data to display the Procedure Data dialog for the corresponding unit procedure or Equipment Data to display the Equi
52. eters in this tab Next referring to the Volumes tab notice that you can specify a maximum and minimum working to vessel volume ratio Change the Max Allowable Working Vessel Volume to 80 Then move to the Reactions tab see Figure 2 17 In this tab you will need to specify the parameters describing a reaction in which a molecule of reagent A combines with a molecule of reagent B to form a molecule of product C A BOC To enter this click Edit Stoichiometry X to bring up the Stoichiometry Balance dialog for Reaction 1 see Figure 2 18 Introduce the reactants pure components A and B and the product pure component C using the Add a Reactant and Add a Product toolbar buttons located above the reactant and product tables respectively Select the Molar option for the specification of the stoichiometric coefficients and keep the default unit molar coefficient for everything for more details on specifying the stoichiometry balance for a reaction see 2 2d Initialization of Reaction Operations Now click OK to close this dialog and return to the Reactions tab E Stoichiometry Balance for Reaction 1 Reactants i Products 1 0000 150 000 150 0000 1 0000 175 000 175 0000 1 0000 25 000 25 0000 Total Mase 175 0000 Total Mass 175 0000 Stoichiometric Coefficients O Mass wv OK x Cancel 2 Help Figure 2 18 The Stoichiometry Balance dialog b
53. fined as new value old value old value Setting the relative tolerance to a larger value may speed up the convergence but may lead to less accurate simulation results Switch from convergence based on the total flow to convergence based on individual component flows This may slow down the convergence process but it will yield more accurate simulation results This is especially important for process files that deal with components that are in trace amounts but whose accurate balance is of utmost importance e g hazardous and or toxic chemicals Increase the maximum number of iterations Request that tear streams be initialized to zero flow for all components before every new simulation Normally in cases where the process simulation has been converged once the initially guessed state for tear streams is their current state at the end of the previous converged simulation In most cases this leads to a faster convergence the next time the mass and energy balances are solved However after a convergence failure it may be better to start with zero values Adjust the Wegstein algorithm parameters qmin max and q If the convergence procedure seems to be unstable raising the value of q e making it less negative may improve convergence if it is converging very slowly but monotonically you might lower Gmin gt and if it is converging in an oscillatory manner try raising qmax You also have the option of a
54. g up the Recipe Scheduling Information dialog see Figure 2 26 below Recipe Scheduling Information Scheduling Inputa Scheduling Outputs Annual Operating Time SOT Batch Time 10 49 h Avalable 732000 R Min Cycle Time 352 k Utilized 384 h A Mas Number of Batches per Year Hb ria 831 Number of Campaigns Per rear i Unit Procedure with Longest Duration Number of Batches Per ear Mb Pl fin W 101 Calculated O Set by User z0 Equipment with Longest Occupancy Recipe Cycle Time Scheduling Bottleneck Set by User m20 h H 101 O Set Cycle Time Slack 2 48 h ES Update OK Cancel Help Figure 2 26 Specifying the scheduling information for a batch process For your example process simulated in Design Mode please change the number of batches per year to 20 This implies that your example process will be run in a pilot plant 20 times this year it is assumed that the equipment used by this process is used by other processes the rest of the year In addition please change the recipe cycle time for this process to 12 hours to reflect the completion of one batch during every 12 hour shift and of the whole process in approximately 240 hours Click Update H to see the actual annual operating time AOT that the plant is utilized by this process Based on the scheduling information and the available AOT specified for the plant the system will do the following 1 Make s
55. gt Operating Cost Adjustments on the Edit menu or you can right click on the flowsheet to bring up its context menu and select Section lt section name gt gt Operating Cost Adjustments note that the term in brackets represents the name of the selected section Through the Operating Cost Adjustments interface the user can adjust parameters that affect the Facility Labor Lab QC QA Utilities Tutorial 2 53 Developing a Process Model 2 54 Tutorial and Miscellaneous costs of a section In your example please change the Facility Cost to be based on an Equipment Usage Rate This will account for depreciation maintenance and miscellaneous equipment expenses To do that uncheck the default option entitled Based on Capital Investment Parameters and check the option entitled Based on Operating Parameters as shown in Figure 2 37 Also make sure that the Usage Basis option is selected for the calculation of equipment hours The equipment usage or availability rates are equipment dependent they are initialized to 100 h and they can be edited through the Adjustments Tab of the Equipment Data dialog Next please visit the other tabs on the above dialog to familiarize yourself with their functions Notice that in the Labor tab there are various options for specifying the labor costs of your process including lumped and itemized estimates for the labor hours and labor cost rate Furthermore the Lab QC QA
56. h the simulation data dialog interfaces described in 2 1h Initializing Unit Procedures and 2 1 Setting the Process Scheduling Information you can also accomplish from the Gantt Chart interfaces To do that simply double click on a bar or right click on a bar and select the uppermost entry on the context menu for that bar This will display the simulation data dialog for the corresponding activity For example e if the bar corresponds to an operation it will display the Operation Data dialog for that operation e if the bar corresponds to a unit procedure it will display the Procedure Data dialog for that unit procedure e if the bar corresponds to an equipment resource available only in Equipment Gantt Charts it will display the Equipment Data dialog for that piece of equipment e if the bar is the one at the top of the chart named complete recipe in Operation Gantt Charts and total equipment occupancy in Equipment Gantt Charts it will display the Recipe Scheduling Information dialog see Figure 2 26 If you change the simulation parameters in the above dialogs you must click Redo Calc amp Update Chart lt on the toolbar or Update Chart on the chart s main menu This will solve the mass and energy balances again and have the Gantt chart updated to reflect the new scheduling settings for the recipe You can change the style e g bar width time scale etc and contents e g displayed a
57. heduling information before performing a simulation SuperPro Designer allows you to specify the following scheduling data 1 For each operation a the process time b the setup and turnaround times and c the starting time 2 For each procedure the number of cycles 3 For the entire plant a the available AOT b the number of campaigns per year c the number of batches per year and either d the cycle time or e the cycle time slack Scheduling of operations was explained in Section 2 1h Initializing Unit Procedures In that section the Scheduling tab of a filtration operation was shown in Figure 2 21 Through the Scheduling tab you can specify the start time of an operation relative to the beginning of a batch or relative to the start or end of other operations in the same procedure or in a different procedure You may also specify the process time if it is not calculated by the model the setup time and the turnaround time for an operation To specify the number of cycles per batch for a procedure the same number applies to all operations of the procedure simply right click on the unit procedure s icon and select Procedure Data from the corresponding context menu By default all procedures start with one cycle 2 38 Tutorial TUTORIAL Developing a Process Model To specify scheduling information for an entire process click Recipe Scheduling Information on the Tasks menu This will brin
58. here are unit procedures that are inherently batch semi continuous e g the Batch Vessel Procedure in a Reactor employed in this example and can only be operated in batch semi continuous mode You can have batch semi continuous unit procedures in continuous process plants Other unit procedures are inherently continuous e g the Centrifugal Pumping unit procedure which is available by clicking Transport near gt Liquids Centrifugal Pump on the Unit Procedures menu By default these can be operated in either mode Thereby you can have continuous unit procedures in batch process plants Note that the operating mode of inherently continuous unit procedures is initially set to batch semi continuous in batch process plants and continuous in continuous process plants You can access or modify where both options are available the operating mode of a unit procedure through its context menu Please right click on a unit procedure icon bring up its context menu The context menu of vessel procedure P 1 after operations are added in this example is shown in Figure 2 12 To view the operating mode setting of a unit procedure click Procedure Data This will display the Procedure Data dialog for that unit procedure The Operating mode specifications can be found in the Scheduling tab of that dialog for more details on the operating mode of unit procedures see Chapter 5 Procedures amp Operations Charge Solvent Charg
59. his tab allows you to edit factors used to estimate the direct fixed capital DFC of a section The Capital Cost Adjustments dialog is brought up by selecting the appropriate section Main Section in this case in the relevant drop down list box on the Section toolbar and then clicking on the Capital Cost Adjustments button on the same toolbar Alternatively you may click Process Options gt Section lt section name gt gt Capital Cost Adjustments on the Edit menu or you can right click on the flowsheet to bring up its context Tutorial 2 51 Developing a Process Model menu and then click Section lt section name gt gt Capital Cost Adjustments note that the term in brackets represents the name of the selected section The Distributed Set of PC Factors in the DFC tab and the Startup and Validation Cost factor in the Misc tab can also be retrieved from a database site by allocating one or more process sections to that database site That is the best way to utilize meaningful parameters for different industries around the globe It is also the recommended way for standardizing cost analysis assumptions For more information on how to take advantage of the database capabilities of SuperPro Designer for cost analysis please consult the SynPharmDB readme file in the Examples SynPharm directory of SuperPro Designer Also see 15 13 Sites amp Resources Databank DFC Cost Allo
60. igure 2 21 Next click OK Next Operation to move to the Operation Data dialog for Cake Wash operation CAKE WASH 1 Cake Wash Solubility Labor etc Description Batch Sheet Scheduling Wash In Stream Duration in 1 5 109 BG Setup Time 000 min Amount Wash Time Available In Wash ln Stream Volume Too Cc Set by User 30 000 rin er Cycle per Unit p p Ci Dehnidadercd etched mt 2 Velut 00 vol vol cake wash Flux 200 000 L mZR per Cake Volume F Wash Dut Stream j Power Consumption Out 6 5 108 Power Type Set Specific Power 0 0000 kwm Wash Type Set Total Power 0 0000 kw H Displacement Set Power per Unit 0 0000 kw Approach To Theoretical 30 0 Es Slum Figure 2 22 The Cake Wash tab for Cake Wash operation CAKE WASH 1 in procedure P 2 In the Cake Wash tab see Figure 2 22 you will need to specify which stream will provide the wash solvent and which one will remove the waste For this example keep stream S 109 as the wash in stream and select stream S 108 as the wash out stream In addition you will need to specify what solvent will be used for the wash To do this click View Edit Stream Composition and or Amount
61. ion and resource tracking Tutorial 2 3 Developing a Process Model 2 4 Tutorial information for this process model is described in sections 2 1 Setting the Process Scheduling Information up to 2 1k Viewing Scheduling Equipment Utilization and Resource Tracking Results 2 GettingStartedS_Ob This file is based on the previous one The mass and energy balances are now solved for known equipment sizes in equipment Rating Mode in order to analyze throughput and economic information A throughput and debottlenecking analysis for this process is described in section 2 11 Throughput Analysis and Debottlenecking Furthermore the specification and analysis of economic information is described in section 2 1m Cost Analysis and Economic Evaluation For continuous processes the steps that are related to scheduling of operations within unit procedures see 2 lh Initializing Unit Procedures and of the entire process see 2 1 Setting the Process Scheduling Information do not need to be performed 2 1a Summary Steps The steps listed below summarize the process of developing a process model with SuperPro Designer These steps are explained in much greater detail in the remainder of this section 1 Start a new process file by selecting option Start a New Process File in the opening dialog of the program Alternatively you may start a new process file later by clicking New B on the Main toolbar or on the File menu of the program
62. is also indicated on the chart This corresponds to the procedure equipment combination that has the smallest batch size potential based on that method In this example P 1 V 101 is the size bottleneck based on any estimation method For each unit procedure the above information can also be found in the Throughput tab of the corresponding simulation data dialog E Throughput Analysis Potential Throughput Conservative Realistic Theoretical Current Batch Size TD oS of ls Q N y Nn 5 gt la za Bottleneck P 1 V 101 Conservative P 1 V 101 Realistic P 1 V 101 Theoretical Cake Total Flow of Stream Cake Figure 2 33 The Batch Size Throughput Potential Chart To omit an equipment resource from the throughput analysis and thereby from the above charts open the corresponding Equipment Data dialog switch to the Throughput tab and check the option named Omit from Throughput Analysis For display purposes a relevant specification setting will be checked in the Throughput tab of all unit procedures that utilize that equipment resource Tutorial 2 47 Developing a Process Model 2 48 Tutorial 2 1m Cost Analysis and Economic Evaluation SuperPro Designer performs thorough cost analysis and economic evaluation calculations and generates three pertinent reports The key initialization steps are described below using our simple process a
63. mation is also available in the Throughput tab of the Procedure Data dialog for each unit procedure Note that the time utilization is somewhat low because some slack time was introduced see Figure 2 26 The combined utilization is the product of the two A batch size throughput bottleneck corresponding to the limiting procedure equipment combination in terms of highest combined utilization P 1 V 101 in this case is also indicated on the chart BATCH SIZE POTENTIAL CHART Furthermore estimates of batch size throughput potential are available in the Batch Size Potential chart To create this chart you must first select a throughput reference rate for batch size calculations To do that select Rate Reference Flow s on the Tasks menu to open the Rate Reference Flows dialog and switch to the Throughput tab Please choose the total flow of the Cake stream as reference and specify the word Cake as the quick reference symbol Then click OK to close this dialog Subsequently select Throughput Analysis gt Batch Size Potential on the Charts menu to view the batch size potential chart using the total flow of the Cake stream as throughput reference rate see Figure 2 33 This chart shows the actual batch size red dotted lines and three estimates conservative realistic and theoretical of batch size potential for each procedure equipment combination A size bottleneck based on each estimation method
64. n t have to add all the unit procedures at once You can always add or remove procedures as desired at a later stage For complex processes it is highly recommended that you begin your simulation with just a handful core unit procedures and add more only after you have successfully completed the simulation for the first phase streams and operations have been initialized correctly and your mass balances make sense USING BREAKPOINTS When simulating large processes it is sometimes useful to solve only part of the process Setting breakpoints tells the simulator to halt calculations at a certain point A brief description of this facility is given below You can place a breakpoint and force the M amp E balance execution sequence to pause either right before or right after the solution of a unit procedure You may even place a breakpoint inside the unit procedure s solution sequence of unit operations gt To Place a Breakpoint on a Unit Procedure 1 Right click on a unit procedure to bring up its context menu and select Set Breakpoints Through the Breakpoints dialog that appears you can specify where to break the simulation of the selected unit procedure TUTORIAL Developing a Process Model 2 Check the place s where you wish the simulation to pause and exit this dialog Notice that red signs are shown above the procedure s icon to indicate that one or more breakpoints are set on this procedure The position of th
65. nd cycle time its duration as well as throughput analysis results for a procedure can be viewed by visiting the corresponding Procedure Data dialog right click on the desired unit procedure icon and click Procedure Data on the context menu of that procedure Operation Data The calculated parameters for an operation can be viewed by visiting the corresponding Operation Data dialog right click on the desired unit procedure icon and choose the operation you are interested in from the Operation Data context menu For instance you Tutorial 2 31 Developing a Process Model 2 32 Tutorial can see how long each of the charge operations takes recall that their durations were based on a given mass to be charged and a flowrate Equipment Contents The contents of a piece of equipment as a function of time can be viewed by right clicking on a unit procedure and selecting Equipment Contents or Procedure Activity Overview on the context menu of that procedure Streams amp Material Balance Report SR A report containing information on raw material requirements stream compositions and flow rates as well as an overall material balance can be generated and displayed by clicking Streams amp Mat Balance SR on the Reports menu This report includes an overview of the process a listing of the raw material requirements a listing of the compositions of each stream and an overall component balance Please generate and view this
66. nent Flow Transter In _Transter Dut Waporize Concentrate Vent Figure 2 13 Adding operations to the Batch Vessel Procedure in a Reactor in the example Subsequently please open the Operation Sequence dialog for the filtration procedure P 2 in the example Notice that this unit procedure has a Filter Cloth Filtration operation named FILTER 1 added to its operation sequence by default Use the same method as before to add a Wash Cake Cake Wash operation named CAKE WASH 1 and a Transfer Out operation named TRANSFER OUT 1 to the operation sequence You can keep the default names for these operations INITIALIZING THE OPERATIONS The next step is to initialize the operations added to the two unit procedures as described below Batch Vessel Procedure in a Reactor Please right click on the vessel procedure P 1 to bring up its context menu and click Operation Data gt Charge Solvent Charge This will bring up the Operation Data dialog for the Charge Solvent operation Through this dialog you can access or modify the simulation data for an operation such as the operating conditions scheduling data emission specifications and labor related information This data is grouped into several tabs Note that Tutorial 2 21 Developing a Process Model different tabs may be available for different operations The operating conditions Oper Cond s tab for th
67. ntext menu At this point please right click on input stream S 101 of the vessel procedure P 1 and click Edit Tag Name on the stream s context menu Change the name of the stream to Heptane and click OK Then right click on the Heptane stream line and click Style gt Edit Style to display the Stream Style dialog In the Stream Line tab see Figure 2 10 of this dialog click Pen Color _ on the Stream Line toolbar and change the color to blue Also click Pen Size on the same toolbar and change the size to 2 pixels Stream Line Name Label Name La Stream Line 5 101 Display Also IX Name Info Tag Figure 2 10 The Stream Line tab of the Stream Style dialog box TUTORIAL Developing a Process Model Now switch to the Name Label tab Click Font Color on the Color Font toolbar and change the color to teal Also click Font 4 on the same toolbar and change the font style to bold and the font size to 12 Then click the Name Label Location tab change the segment preference to Vertical Near Source and click OK Next please change the name of stream S 106 the stream that is connected to the dedicated cake removal port of the Plate amp Frame Filter to Cake Also apply the style of the Heptane stream to the Cake stream and to the intermediate stream S 105 using the shortcut method described
68. ocedures that are operated in batch semi continuous mode The Procedure Data item allows you to access or modify the simulation parameters of the unit procedure such as the operating mode continuous or batch semi continuous and additional scheduling throughput analysis and debottlenecking information The Procedure State Properties item allows you to access or modify thermodynamic state properties of pure components during each operation Through the Procedure Activity Overview item you can view a summary of scheduled Operations processed material and equipment contents during the execution of the unit procedure The Equipment Data item allows you to access or modify the simulation parameters of the host equipment such as sizing costing and scheduling information The Equipment Contents item allows you to access or modify the initial equipment contents and also view a summary of the thermodynamic properties and composition of the equipment contents during the execution of the unit procedure The Set Break Points item allows you to place stops in the sequential solution of mass and energy balances This is normally used for troubleshooting in large or complex process simulations The Edit Labels item allows you to change the name of the unit procedure the name of the host equipment and the description of the unit procedure For example you can change the default unit procedure name P 1 equipment name V 101 and unit procedur
69. ons for fed batch supply of reactants and a Reactions tab see Figure 2 17 in which reaction parameters are specified Oper Cond s Volumes Fed Batch Reactions Vent E missions Labor ete I Description Batch Sheet Scheduling Reaction Data Reaction Sequence Name Reaction t Parallel 7 Reaction Limiting Comp none Extent Achieved 0 000 EA Reaction 1 Reaction Progress Reaction Limiting Component Ref Comp none Extent Achieved 0 000 a Calculate to Achieve Target Concentration fo o000 oL Blot inore Reaction Heat Ignore X Enthalpy 0 0 kcal kg for Reference Comp none S at Reference Temp 25 0 E Based on Reaction Molar Stoichiometry 1 004 1 006 1 000 Figure 2 17 The Reactions tab for Batch Stoichiometric Reaction operation React in procedure P 1 Starting with the operating conditions tab please change the final temperature to 50 C and the process time to 6 hours Also select Steam as the heat transfer agent by clicking the Agent TUTORIAL Developing a Process Model drop down list box and double clicking Steam on the Heat Transfer Agents drop down listing that is available in the right pane Keep the default values of all other param
70. ow the user to quickly and easily analyze the capacity and time utilization of each piece of equipment and to identify opportunities for increasing throughput with the minimum possible capital investment The most important features are e the Utilization Factors chart and e the Batch Size Potential chart which indicates opportunities for increased production per batch For a detailed throughput analysis example based on the process of the second example see Chapter 11 Debottlenecking A brief description is given here Since throughput calculations are based on fixed equipment set all pieces of equipment to Rating Mode Specify 1630 L for the reactor and 2 m for the filter as was done for file GettingStarted8_Ob in subdirectory Examples Misc Then solve the model UTILIZATION FACTORS CHART Select Throughput Analysis gt Utilization Factors on the Charts menu The Utilization Factors chart shown below will appear E Throughput Analysis Utilization Indices j Legend Size Throughput Utilization Time Utilization Combined Uihzaton S eo p a N T F 2 PFF 101 Bottleneck P 1 V 101 Figure 2 32 The Utilization Factors Chart The chart shows for each unit procedure the capacity size utilization how full the equipment is and the time utilization its uptime or busy time of the hosting equipment TUTORIAL Developing a Process Model This infor
71. ox for the example reaction In addition to specifying the stoichiometric reaction coefficients you will need to specify the extent of the reaction For this example set the extent to 95 as was done in Figure 2 17 Leave all the default values for the Vent Emissions Labor etc and Scheduling tabs and click OK Next Operation to move to the Operation Data dialog for the Transfer Out operation Transfer to PFF 101 In the operating conditions tab see Figure 2 19 use the drop down menu at the top of the screen to specify which stream will be used for the transfer operation stream S 105 is the only choice for this example In addition in order to accurately capture the time required for this operation set the duration to be the same as the duration of the filtration operation in procedure P 2 To do that select the Set By Master Slave Relationship duration option and then click the Setup button Through the dialog that comes up select P2 in PFF 101 as the Master Procedure through the Another Procedure drop down list FILTER 1 Cloth Filtration as the Master Operation through the Match a Single Operation drop down list and then click OK This will ensure that the reactor will be Tutorial 2 27 Developing a Process Model 2 28 Tutorial considered utilized during filtration since the reactor will not be completely emptied until the filtration is comple
72. pment Data dialog for the corresponding equipment In the Scheduling tab of that dialog you can see among others the total equipment occupancy time per batch The equipment with the least idle time between consecutive batches or equivalently the longest occupancy time per batch is considered the time or scheduling bottleneck V 101 in this case This is the equipment that determines the maximum number of batches per year Its occupancy time per batch 9 52 hours in this case corresponds to the minimum cycle time of the recipe the minimum possible time between two consecutive batch starts The total equipment occupancy time per batch 12 hours in this case corresponds to the actual cycle time of the recipe the actual time between two consecutive batch starts To view this information right click on an empty area in the chart to bring up the chart s context menu and check Scheduling Summary This will display the Recipe Scheduling Summary dialog for TUTORIAL Developing a Process Model the process That dialog presents for display purposes only the same information as the Recipe Scheduling Information dialog of Figure 2 26 To change the style and contents of the Equipment Occupancy Chart right click on an empty area in the chart to bring up the chart s context menu and select Edit Style Please refer to the synthetic pharmaceutical example see Figure 2 50 and the B Galactosidase example see Figure 2 58
73. ports Tutorial 2 57
74. poses of this example the only physical parameter we will be concerned with is the molecular weight MW Please go to the Physical Constant tab and change the MW of component A to 150 g gmol as shown in Figure 2 5 Also visit the Economics tab and specify a purchasing price of 10 kg Then click OK to close the dialog Economics I Pollutant Categori f IDs j Physical Constant Fhys Main Properties iw J g gmol Enthalpy of Formation 285830 00 Jigroal Normal Boiling Point 10000 C Normal Freezing Point foo ee Critical Properties Temperature 374 13 JE Pressure 221 20 bar Compressibility Factor 0 2350 Acentric Factor Omegal o3440 Miscellaneous Henry s Const x10 4 0 000000 atm m gmol Farticle Size 0 00 7 micron Default Volumetric Coefficient 1 00 Figure 2 5 Editing the constant physical properties of component A in the example Next please visit the properties dialog for component B and enter a MW of 25 g gmol and a purchasing price of 15 kg Also visit the properties dialog for component C and enter a MW of 175 g gmol and a selling price of 300 kg This completes your initialization of components for our simple example To delete a registered pure component highlight that component in the list of registered pure components and click Delete x on the Registered Pure Components toolbar You can add regist
75. r the purposes of this example let us assume that reagents A and B are completely soluble in Heptane whereas the product C is virtually insoluble in Heptane In the Particulate Component Removal table that is available on the top left corner of this tab please specify that 95 of your product C will be removed from the feed stream and will remain on your filter whereas the rest will end up in the filtrate Also notice that you can specify a cake dryness either based on loss on drying LOD or cake porosity This value will cause a portion of the Heptane solvent and of soluble components A and B to be held in your wet cake Please change the LOD for your filtration to 35 By specifying a LOD of 35 you are telling the program that only 65 of wet cake is the insoluble product C For this operation please specify a filtration time of 3 TUTORIAL Developing a Process Model hours Keep the rest of the parameters such as the filtrate flux of 200 L m h as they are and also keep stream S 107 as the filtrate stream Fa i per Cond s Labor etc Description Batch Sheet Scheduling Setup Time 0 00 min Filtration Time Set by User 3 000 h Heptane eee Nitrogen Filtrate Flux 200 000 L me h Osygen Water Filtrate Stream Out H3 5 107 Cake Dryness Fower Consumption Q LoD 35 00 Power Type Cake Porosity 040 vi Set Specific Power 0 000
76. rawing of the stream TUTORIAL Developing a Process Model 2 Move the mouse pointer over the desired inlet port of the destination unit procedure and once the port pointer is displayed click on the port to terminate the stream line SuperPro Designer automatically labels the stream gt To Add a Product Stream 1 Move the mouse pointer over the desired outlet port of the source unit procedure and once the port pointer is displayed click on the port to initiate drawing of the stream 2 Double click on an empty area of the flowsheet to terminate the stream SuperPro Designer automatically draws the product stream and labels the stream Note that between initiation and termination of a stream you may optionally click at intermediate points on the screen to create right angle bends This permits customizing of the stream route and flexibility in flowsheet design You can cancel the stream drawing process at any time by simply hitting the Esc key on your keyboard Then you can restart the stream drawing process by clicking Connect Mode 3 again on the Main toolbar To delete a stream simply hit the Delete key on your keyboard At this point please add the feed intermediate and product streams to your example process Your flowsheet should now look like what is shown in Figure 2 8 SuperPro Designer GettingStarted8 Oa Pt File Edit Unit Procedures Tasks Charts View Reports Databanks window Help TE hel Gil ae
77. report now To see more comprehensive stream reports please refer to the synthetic pharmaceutical example see 2 2e Process Analysis the B Galactosidase example see 2 3e Process Analysis and the industrial wastewater treatment example see 2 4b Process Analysis If you wish to customize the stream report click Options on the Reports menu and switch to the Stream tab for more details on reports see Chapter 12 Reports Equipment Data To see the calculated number and size of equipment units right click on a unit procedure icon and click Equipment Data on the context menu of that procedure This will bring up the Equipment Data dialog of the equipment resource that hosts that procedure At this point please open the Equipment Data dialog for Plate amp Frame Filter PFF 101 shown in Figure 2 23 Equipment Scheduling Throughput Comments Purchase Cost Adjustments Consumables Selection B Description oO Select PFF 101 Hame PFF Oo i Mame e Number of Units cee Size Calculated Design Mode O Set by User Rating Mode Fiter Area 13762 m2 day Mas Fiter Area fso oo00 me Stagger Mode Use D extra sets of equipment units i a Warnes Figure 2 23 The Equipment tab for Plate amp Frame Filter PFF 1 All unit procedures have two options for equipment sizing TUTORIAL Developing a Pro
78. s please specity the operating mode and the annual operating time available to this process Process Operating Mode Batch Scheduling information i required Process Batch time i calculated Stream flows are displayed on a per batch basis Inherentl continuous processing steps can be included as unit operations in ether continuous or semi continuous mode O Continuous Scheduling information is NOT required Process batch time is NOT calculated Stream flows are displayed on a per hour basis nherently batch processing steps can be included User must speci process time and turnaround time for such steps Annual Operating Time for all campaigne o DK Cancel Annual Operating Time Available 7920 00 h Figure 2 2 The Process Operating Mode dialog box 2 1d Setting the Default Physical Units SuperPro Designer provides a variety of options for units of measure for the entry and display of data To view or modify the default units of the process model click on an empty area in the flowsheet and select Process options gt Physical Units Options on the Edit menu Alternatively right click on the flowsheet to bring up its context menu and select Physical Units Options To activate the Process Options menu item on the Edit menu you must first click on an empty area of the flowsheet 2 1e Registering Components and Mixtures COMPONENT DATAB
79. s the options available for calculating the facility dependent operating cost Facility Labor Lab OC QA Utilities Misc X Based on Equipment Usage Ayvailability Rate Facility Dependent Cost SUMIEquipment Rate s Equipment Hours Equi tH Calculati Saah E 4 ii Include Exclude Equipment Usage Basis Availability Basis Based on Facility Availability Rate Use Site Data Facility Dependent Cost Facility Availability Rate Hours of Availability Facility Availability Rate 500 00 facihty h Based on Capital Investment Parameters Facilt Dependent Cost Depreciation Maintenance Miscellaneous IX Include Maintainance O Use Equipment Specific Multipliers O Estimate as 6 00 DFC Direct Fixed Capital Include Depreciation Use Contribution From Each Equipment s Undepreciated Purchase Cost O Use Section DFC Portion Already Depreciated 0 00 7 IX Include Misc Costs Use Site Data Insurance 1 00 DFC Local Taxes 2 00 SURE Factory Expense 5 00 DFC Figure 2 37 Adjusting the operating cost parameters at the section level This dialog is brought up by selecting the appropriate section Main Section in this case in the Section Names drop down list that is available on the Section toolbar and then clicking Operating Cost Adjustments 38 on the same toolbar Alternatively you may select Process Options gt Section lt section name gt
80. s an example see also file GettingStarted8_Ob in the Examples Misc subdirectory of SuperPro Designer For a detailed description of cost analysis and economic evaluation please consult Chapter 9 Economics SUPPLYING REVENUE RAW MATERIAL AND WASTE STREAM DATA This step must precede economic evaluation and environmental impact assessment calculations Please select Stream Classification on the Task menu You will be presented with a dialog window see Figure 2 34 where you can classify all input and output streams as raw materials revenues or wastes solid aqueous organic or gaseous and supply any cost data associated with the classification By default the system estimates a purchase or selling price for a stream based on the price of each component and the composition of the stream The price of a pure component or stock mixture is part of its properties which can be edited when registering components as described in 2 le Registering Components and Mixtures E Stream Classification Classification of Output Streams I Emission 0 100000 kg Revenue 195 260660 kg Aqueous Waste 0 100000 kg Aqueous Waste 0 100000 kg Classification of Input Streams Main Product Revenue Stream Name Classification Purchase Price Units Set By Steam Cake or Processing Fee os Heptane Raw Material 0 360000 kg Flow Basis 5 102 Raw Material 10 000000 kg Total Stream Flow 5 103 Raw Material 15 000000 kg
81. s file later by clicking New Q on the Main toolbar on the File menu 2 1 Specifying the Mode of Operation for the Entire Plant After you choose to start a new process file the Process Operating Mode dialog box will appear as shown in Figure 2 2 This dialog box allows you to set the primary mode of operation batch or continuous and the annual operating time available for the entire process You can also modify these settings at a later time by clicking Set Mode of Operation on the Tasks menu When the process operating mode is set to Batch all stream flows are displayed on a per batch basis On the other hand when the process operating mode is set to Continuous all stream flows are displayed on a per hour basis Moreover no scheduling information is necessary for plants operating continuously Please note that although the plant operation mode can be either batch or continuous SuperPro Designer can also model processes that operate in mixed modes That is you can have continuous unit procedures in a batch process plant as well as batch semi continuous cyclical unit procedures in a continuous process plant This is explained later in this chapter see 2 1h Initializing Unit Procedures Tutorial 2 5 Developing a Process Model 2 6 Tutorial For now let s select Batch as the operating mode of this example process E Process Operating Mode Batch vs Continuous Ed Before you start a new proces
82. s into different categories e g raw material revenue waste etc using item Stream Classification on the Tasks menu and c perform costing and economic evaluation calculations by clicking Perform Economic Calculations on the Main toolbar or on the Tasks menu Other analyses related to scheduling throughput and debotttlenecking may be optionally performed TUTORIAL Developing a Process Model 6 Generate charts and view analysis results using items of the Tasks Charts and View menus Generate and view reports using items of the Reports menu 2 1b Starting a New Process File To open SuperPro Designer after it has been installed select the program shortcut on the Windows Start Menu or double click the file Designer exe in the installation directory of the application The following dialog box will appear by default E What Would You Like To Do O Start a New Process File Open our Last Process File D Mnteligens SPD FilessExamples_v SExamples Bgal BGal 5c spt Open Another Process File DO ntelligen lt SPD Files E samples _vr5 Finalh B gat B Gal _5a spf pas will Choose Later af DK Help Do Not Show This Dialog Again D Figure 2 1 The opening dialog box of the program To begin working on a new process file select the option named Start a New Process File from the above dialog and click OK If you select another option and close this dialog you can always start a new proces
83. s into the clipboard so that you can subsequently paste them to a different location either in the same flowsheet or in another flowsheet To do this 1 Select the desired unit procedure icon s 2 To cut the icon s click Cut on the Edit menu or press Ctrl X To copy the icons click Copy on the Edit menu or press Ctrl C 3 Move the mouse cursor to the desired area in the same flowsheet or in another flowsheet and click Paste on the Edit menu or press Ctrl V to paste the icon s The following restrictions apply to the use of the Cut Copy and Paste features TUTORIAL Developing a Process Model 1 You cannot cut or copy and paste streams alone Streams are placed onto the clipboard only if you cut or copy multiple unit procedures 2 When pasting unit procedures into a flowsheet you should be aware that certain features of the original unit procedures are not transferred into the newly created copy a When you cut or copy a single unit procedure attached streams are not included in the pasted set b If the start time of the first operation of the pasted unit procedure was defined on a relative basis e g with respect to the start or end of another operation in some other procedure then the scheduling of the pasted procedure is reset to remove the coupling c If the original unit procedure was sharing equipment with another procedure the pasted procedure is reset to be executed in its own equipment 3 Pas
84. st a breakdown of the annual operating cost and a description of profitability analysis calculations Please generate and view the Economic Evaluation Report now 4 Another useful economic report is the Itemized Cost Report ICR This report contains detailed cost breakdowns of the total annual operating cost over all process sections This includes all cost items that are calculated at the section level Additional cost items that are calculated at the process level are not considered To generate this report select Itemized Cost ICR on the Reports menu Tutorial 2 55 Developing a Process Model 2 56 Tutorial 5 Finally a Cash Flow Analysis Report CFR can be generated This report includes loan information and detailed breakdowns of capital outlay loan payment and cash flow for each year over the expected lifetime of a project To generate this report select Cash Flow Analysis CFR on the Reports menu The equipment purchase cost shown in the Purchase Cost tab of the Equipment Data dialog corresponds to a single equipment unit For more information on the contents of the economic reports please refer to the synthetic pharmaceutical example see 2 2f Cost Analysis and Economic Evaluation the p Galactosidase example see 2 3f Cost Analysis and Economic Evaluation and the industrial wastewater treatment example see 2 4c Cost Analysis and Economic Evaluation For a detailed description of economic reports see Chapt
85. t stream To add a stock mixture to the stream select the Stock Mixtures option for registered ingredients and follow the same guidelines as for adding components 3 As an alternative to going through the simulation data dialogs of operations to edit stream properties you can initialize and edit input streams directly from the flowsheet itself To do this double click on a stream or right click on a stream and click Simulation Data from the context menu of that stream This will bring up the same dialog box as the one shown in Figure 2 15 Note that only the feed input streams to the flowsheet need to be specified Tutorial 2 23 Developing a Process Model 2 24 Tutorial The flowrates and compositions of intermediate and output streams are calculated by the program However the user can specify the physical state properties of these streams 4 For biotech processes the extracellular percentage Extra Cell of an ingredient represents the fraction of that ingredient in the bulk solution as opposed to inside the cell For more information on this topic please refer to the B Galactosidase example see 2 3 The b Galactosidase Process 5 If the plant operation mode is batch all flowrates are reported on a per batch basis or per cycle of source or destination process step If the process plant is set to operate in continuous mode then all flowrates are reported on a per hour basis The choice for mass units can be
86. tate l Env Properties Comments Registered Ingredients Composition Components Stock Mixtures Set Ingredient Flows Mass Composition Total Flawrates Auto Adjust T Temperature 25 00 a O Set Mass Flow 0 000 kg batch Pressure 7 013 Ear Set ol Flow 0 000 L batch Activity og Uml Units Massin kg Volume in L Composition in 2 Cone in g L Time Ref for Flows O Batch Source Cycle Destination Cycle Time Average e Ir E w K E 2 TA Figure 2 15 The simulation data dialog for the Heptane stream Please note the following with respect to the simulation data dialog of streams 1 You can charge multiple components in the same stream if you wish To do this simply add additional component names from the Registered Ingredients listing If the Ingredient Flows option is selected you can specify the corresponding amounts of added ingredients The computer will automatically calculate the mass and concentration g L or mole L of each ingredient the stream s density if it is not set by the user the volumetric flowrate and the activity of the stream If the Mass Composition option is selected you can specify the total mass or volume flow and the mass of each component You may also select units for entry and display 2 In addition to pure components stock mixtures can be fed or charged into a process step using an inpu
87. te You can leave the default values for the other tabs in this dialog Click OK to return to the flowsheet Oper Cond s Yolumes Vent Emissions Labor etc Description E atch Transter Out Using Out 9 5 105 Amo unt E Coe a jiii Q Set Percent 100 00 of vessel contents Set Mass uoa E Le Set Volume oo E A Duration Setup Time oog mn Process Time SetbyUser z000 min 4 Calculated Based on O Mass Pause e0000 kgh O Ai Yahir P aae E00 000 L h Ra Set by Master Slave Relationship Setup The duration of this operation is matched from first to last cycle basis to the duration of Operation FILTERA in Procedure P 2 fir PFF 1011 Ignore Labor Figure 2 19 The Oper Cond s tab for Transfer Out operation Transfer to PFF 101 in procedure P 1 Plate and Frame Filtration Procedure Next you will need to initialize the operations in the filtration procedure P 2 Please right click on unit procedure P 2 and select Operation Data gt FILTER I Cloth Filtration from the context menu of that unit procedure This will bring up the Operation Data dialog for the Cloth Filtration operation named FILTER 1 The operating conditions tab for this operation is shown in Figure 2 20 Fo
88. ting streams and certain processing steps with component and stock mixture related specifications from one flowsheet to another is not possible unless all components and stock mixtures of the source process model exist in the destination process model as well If that is not the case the program will automatically expand the set of registered pure components and stock mixtures in the destination process to include the missing ones If you want to paste icons into another application e g a word processing application please consult Chapter 14 Exchanging Data with Other Apps Accessing the Help Files In many equipment resources that host unit procedures there are dedicated ports such as Feed Vent Emissions Cake Removal Filtrate Removal etc To see which ports are Plate and Frame Filtration Procedure Overview A Plate and Frame Filtration Procedure can be created by selecting the following menu option Unit Procedures gt Filtration gt Plate and Frame Filtration Vent Operating Mode Batch Only Cake Host Equipment Plate amp Frame Filter Feed Emissions Port Yes Vent Special Yes Input Output Ports This unit procedure can simulate filtration and cake for removing suspended solids from a slurry Plate amp frame filters are widely used in the chemical food and environmental industries Special Inputs Outputs e Cake the designated output port for the cake Operations Figure 2 7 Th
89. to see Equipment Occupancy Charts for more complex processes For more information on Equipment Occupancy Charts see 7 6 The Equipment Occupancy Chart EOC RESOURCE DEMAND CHARTS In addition to creating Gantt charts for equipment utilization and operations SuperPro Designer automatically generates graphs of resource demand as a function of time for such things as raw materials labor heating and cooling utilities and power These can be accessed through the Charts menu For instance to view the labor demand for this example process select Labor gt Multiple Batches on the Charts menu Next in the labor resource selection dialog that pops up keep the default selection Operator and click OK Figure 2 29 displays the Operator labor resource demand graph for two consecutive batches To add more right click on the chart to bring up the chart s context menu and select Set Number of Batches As shown in this chart two operators are required to handle this process If you move the cursor close to a peak SuperPro Designer displays the operations that create that peak W Operator Demand Multiple 2 Batches F S tn a e PA D a s 2 purun suosied u 10q e T Figure 2 29 The Operator labor resource demand chart for the example process To change the contents variables displayed and style e g color thickness etc of a resource demand graph right click on the chart to
90. tory falls to 10 or 30 kg of the capacity The replenishment should be halted when the inventory reaches 85 or 255 kg of storage capacity Click OK to return to the previous dialog Resource Inventory Data for Ingredient A Storage Supply Rate 200 00 kgh Capacity O Set by User oe kg Start Time O fate Prd O se 000 h H a Pa whos LEAT EAR Initial Contents O Synchronize with First Draw Ts Schedule O Fixed Ordnterval 1 00 h OfeInterval 7 00 h Max 100 00 4 Variable Min foo0 z On Trigger 10 00 Off Trigger 85 00 O ETa Borba Figure 2 30 The Resource Inventory Data dialog Next click the Chart Style button to bring up the Inventory Chart Style dialog Switch to the Time Line tab and click the Edit button In the Default Time Line Style dialog that comes up change the minor time units count to 12 hours the recipe cycle time and click OK to return to the previous dialog This will make observation of batches easier since a new batch cycle starts every 12 hours in this example Click OK again to continue and the chart will be displayed with two batches Set the number of batches to 12 by right clicking on the chart and selecting Set Number of Batches from the context menu that pops up The resulting chart will look like that of Figure 2 31 The brown line corresponds to the inventory level and the TUTORIAL
91. urchase cost The most common value is 0 3 meaning that the installation cost is 30 of the equipment purchase cost Maintenance Cost Factor This factor is used to estimate the annual maintenance cost for each piece of equipment The most common value is 0 1 meaning that the annual maintenance cost is 10 of its purchase cost TUTORIAL Developing a Process Model Portion of Purchase Cost Already Depreciated Oftentimes a piece of equipment has already been either fully or partially depreciated This can be captured using this variable Any values other than 0 0 reduce the cost of depreciation but have no impact on the maintenance cost because that cost depends on the full purchase cost and not just the un depreciated portion Usage and Availability Rates These factors represent the equivalent of equipment rental rates They are optionally used to estimate the Facility Dependent overhead cost for a description of this cost see Chapter 9 Economics If a piece of equipment is shared by multiple unit procedures its purchase cost dependent expenses e g depreciation maintenance etc are distributed to its hosting steps based on the occupation time of each step Cost of Consumables Consumables include materials and items that need to be replaced periodically such us chromatography resins cartridges of membrane filters lubricants of equipment etc Disposable equipment such as plastic bags plastic bioreactors roller bottles
92. ure there is no conflict created by the specified start time and end time of processing steps Conflicts can be created if the cycle times of procedures that share equipment overlap Make sure there is no conflict between the specified available AOT the specified or calculated number of batches and the specified or calculated recipe cycle time Calculate the number of batches if not set by user the recipe batch time the recipe cycle time if not set by user the recipe cycle time slack if not set by user the utilized AOT the plant s minimum cycle time with maximum batch overlapping the maximum number of batches possible the longest procedure 1 e the procedure with the longest total cycle time and the scheduling bottlenecking equipment the equipment with the longest occupancy time Tutorial 2 39 Developing a Process Model 2 40 Tutorial 2 1k Viewing Scheduling Equipment Utilization and Resource Tracking Results A variety of scheduling equipment utilization and resource tracking tools are included in SuperPro Designer These include e Operations Equipment Gantt Charts e Main and Auxiliary CIP Skids SIP Panels Equipment Occupancy Charts e Resource Demand Charts and e Resource Inventory Charts OPERATIONS EQUIPMENT GANTT CHARTS The Operations Gantt Chart and the Equipment Gantt Chart display scheduling and equipment utilization information respectively for a batch process recipe in the form of
93. waiting for Simulation to Start a aye P 2 PFF 101 F amp F Filtration Pad 101 essel Procedure rH GettingStart For Help press Fl Figure 2 6 The example process with the Batch Vessel Procedure in a Reactor and Plate and Frame Filtration Procedure icons added If you decide to abort the addition of the new unit procedure you can simply hit the Ese key on your keyboard If you wish to modify the default equipment prefixes e g V for a Stirred Reactor CSTR vessel and PFF for a Plate amp Frame Filter click Application Settings on the File menu and go to the Prefixes tab To edit the prefix of an equipment resource highlight that equipment in the available list and click on the corresponding prefix Through the same tab you can also modify the default operation prefixes in the same manner for more details see 8 20 Application Settings Tutorial 2 11 Developing a Process Model 2 12 Tutorial Moving Copying and Deleting Unit Procedures The following guidelines show how you can move or delete unit procedures in a flowsheet and how you can cut or copy and paste unit procedures to a different location in the same flowsheet or in another flowsheet First you need to select the desired unit procedure icon s You can select a single icon by clicking on it You can select multiple icons by either dragging an enclosing rectangle around them or by adding icons to the selection To add an i

Case study : Reaction /Filtration

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