Home

Chemical Hygiene Plan - Southern California University of Health

Contents

1. Hazards Task hands on work or being within reach of potential hazards Minimum Requirements of described activity items Skin eye Laser radiation Goggles appropriate to beam damage parameters closed shoe no jewelry reflective items Class 3b and 4 lasers Skin cover on all potentially exposed areas Infectious Human blood cells tissue body fluids or Safety glasses exam gloves skin disease materials derived from same cover on all potentially exposed areas shoes socks work at Biosafety Level Il Liquid with vol gt 1 mL Same but splash goggles skin cover to throat wrists ankles Skin eye Hazardous solids Safety glasses goggles for large damage quantities chemical resistant gloves poisoning skin cover to elbows knees throat inhalation of closed shoes socks airborne dust gt 100 g any hazardous solid or gt 1 g chemical requiring designated area list at REM web site or High potential for airborne particles Same except skin cover to wrists ankles and only work in hood Cell damage area contamination Radioactive materials Shielding and badging requirements prescribed in specific isotope SOP use all appropriate chemical and or biological safety personal protection NOTES a Being within reach of potential hazards within reach varies widely depending on scale and conditions of work and will be judged by affected staff in each room b Unshielded not behind a dr
2. Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Appendix D CERTIFICATION OF HAZARD ASSESSMENT Example INTRODUCTION Hazard assessment is the process required by law of identifying the hazards associated with defined task prescribing personal protective equipment and other relevant protection measures which must be employed to reduce the risk from the hazards Certification of Hazard Assessment is a written document such as the one on the following 2 pages detailing the hazard assessment s for a particular task s The supervisor is responsible for ensuring that hazard assessments are performed and the certification s written and posted The supervisor may delegate or contract the labor involved in this process but cannot reassign or disclaim the responsibility INSTRUCTIONS e Save the attached hazard assessment example to your hard drive e It must be modified to meet the specific hazards of your work area This includes removing or adding hazards as applicable to your work area e Certification s of hazard assessments must be p
3. Hazard assessments can be organized using three formats by individual task e g pipetting hazardous liquids by location e g Chemistry Laboratory Room or by job title e g Chemistry Lab Technician Any of these formats is acceptable and often will be used in conjunction with each other to provide the safest laboratory work environment possible for employees The following subsections describe each hazard assessment format in more detail 7 2 TASK EVALUATION HAZARD ASSESSMENT Task evaluation hazard assessments should be conducted for specific tasks such as preparing dilute hydrochloric acid solutions or an ozonolysis reaction and workup These types of hazard assessments should be written in a very detailed manner The following describes the steps that should be taken to perform a task evaluation hazard assessment e Describe the task e List hazards associated with each body part e Determine PPE requirements for each hazard e List other control measures required such as engineering and administrative controls 7 3 LOCATION EVALUATION HAZARD ASSESSMENT Location evaluation hazard assessments should be conducted for specific areas laboratories These types of hazard assessments should be written in a comprehensive manner that includes the majority of hazards present in a specific location e g flammable and corrosive liquids This type of hazard assessment is the most commonly used in laboratories and should be posted in a lo
4. awaiting proper characterization 62 8 2 WASTE STORAGE REQUIREMENTS Hazardous waste containers in SCU laboratories are stored in satellite accumulation areas SAA inside the Anatomy Lab cold storage and inside the L 120 chemical storage room SAAs are used to manage hazardous waste in laboratories and shops because doing so provides safe and effective means to accumulate hazardous waste before removal by AOPP Additionally SAAs provide the least restrictive regulatory option for the accumulation and storage of hazardous waste containers AOPP reserves the right to issue citations for lab workers who improperly handle or label hazardous waste The following SAA rules must be followed at all times when managing hazardous waste in a laboratory e All waste must be stored and in labeled containers e Containers must be in good condition and compatible with the waste they contain no corrosive waste in metal containers e Containers must be kept closed at all times except when adding or removing waste e Containers must be labeled or clearly marked with words that describe the contents of the waste e g liquid chromatography waste and the words Hazardous Waste e Containers must be stored at or near the point of generation and under the control of the generator of the waste wastes should remain in the same room they were generated in A central waste collection room should not be established e The waste storage volume should ne
5. Emergency Contact Click here to enter text Name and Phone Number Location s covered by this SOP Click here to enter text Building Room Number Type of SOP O Process Hazardous Chemical O Hazardous Class Purpose Click here to enter text Physical amp Chemical Properties Definition of Chemical Group CAS Click here to enter text Class Click here to enter text Molecular Formula Click here to enter text Form physical state Click here to enter text Color Click here to enter text Boiling point Click here to enter text 75 Potential Hazards Toxicity Click here to enter text Personal Protective Equipment PPE Respirator Protection Click here to enter text Respirators should be used only under any of the following circumstances As a last line of defense i e after engineering and administrative controls have been exhausted When Permissible Exposure Limit PEL has exceeded or when there is a possibility that PEL will be exceeded Regulations require the use of a respirator An employer requires the use of a respirator There is potential for harmful exposure due to an atmospheric contaminant in the absence of PEL As PPE in the event of a chemical spill clean up process Lab personnel intending to use wear a respirator mask must be trained and fit tested by EH amp S This is a regulatory requirement Hand Protection Click here to enter text NOTE Consult with your preferred
6. Unknown chemicals are a serious problem in laboratories Mysterious chemicals are often stored in labs for years before lab personnel notice the unidentified items However steps can be taken to assist with proper management of unknowns Unknown chemicals must be properly identified according to hazard class before proper disposal The hazards that should be noted include corrosive flammable oxidizer reactive toxic and radioactive The following subsections describe in detail how to properly manage unknown chemicals If you are unable to determine what precise chemical is being handled DO NOT GUESS AOPP will arrange for a third party vendor to come and safety test and remove the chemical 8 5 1 LABELING UNKNOWN CHEMICALS Until the unknown chemical can be properly identified by either lab staff or AOPP the container should be labeled with a Hazardous Waste Disposal Tag The following information should be written on the label Unknown hazardous chemical awaiting proper characterization by AOPP as illustrated in Figure 8 7 64 Figure 8 7 Properly Labeled Unknown Waste 8 5 2 IDENTIFYING UNKNOWN CHEMICALS Every effort should be made by laboratory personnel to identify unknown chemicals Here are a few steps that can be taken to help this effort 1 2 Ask other laboratory personnel if they are responsible for or can help identify the unknown chemical The type of research conducted in the laboratory can be usefu
7. a task evaluation hazard assessment e Identify hazards that the position title may encounter while performing normal duties e List each task where hazard is present e Determine PPE requirements for each task e List other control measures required 7 5 MINIMUM PPE REQUIREMENTS FOR LABORATORIES This section details the minimum PPE requirements for all laboratories using hazardous chemicals These requirements do not apply to labs that involve solely mechanical computer laser or other non ionizing radiation or electrical operations The requirements listed do not cover all operations in all laboratories Some operations and procedures may warrant further PPE as indicated by the SDS the SOP for the chemical s being used facility policies hazard assessment or regulatory requirements Figure 7 1 illustrates the minimum PPE required when using hazardous chemicals in a laboratory 57 Safety Glasses or Goggles Lab Coat Chemical Resistant Gloves Long Pants Closed Toe Shoes Figure 7 1 Appropriate PPE for the Laboratory Head Protection If there is a serious risk of chemical splash to the head a chemical resistant hoodie must be worn Each affected employee must wear protective helmets when working in areas where there is a potential for injury to the head from falling objects or bump hazards Hearing Protection Hearing protection is not typically required in laboratory settings However if the lab seem
8. accidental damage Sharp corners and projections are to be avoided Flexible cords and cables must be protected from damage when they pass through doorways or other pinch points Wet or Damp Locations Work in wet or damp work locations i e areas surrounded or near water or other liquids should not be performed unless it is absolutely critical Electrical work should be postponed until the liquid can be cleaned up The following special precautions must be incorporated while performing work in damp locations e Only use electrical cords that have GFCls e Place a dry barrier over any wet or damp work surface e Remove standing water before beginning work Work is prohibited in areas where there is standing water e Do not use electrical extension cords in wet or damp locations and e Keep electrical cords away from standing water 7 LABORATORY PPE POLICY Purpose The purpose of this Laboratory Personal Protective Equipment PPE Policy is to ensure that all SCU lab employees are aware of the PPE requirements and procedures to adequately protect themselves against chemical radiological biological or mechanical hazards This policy has been prepared in accordance with the requirements of the OSHA PPE regulations 29 CFR 1910 132 29 CFR 1910 140 29 CFR 1910 95 As briefly discussed in Chapter 4 of the CHP PPE should never be used in place of engineering and administrative controls 55 Scope This Laboratory PPE Policy appl
9. be any open chemicals in a refrigerator or freezer All containers must be completely sealed or capped and safely stored Chemicals should be allowed to warm to room temperature before sealing to prevent pressure buildup 42 Shelves in refrigerators or freezers should all have suitable plastic trays for secondary containment in the refrigerator and freezer compartments If plastic trays are not available liquid chemicals should be placed in secondary containers to contain spills Remember that power outages and technology failures can cause internal temperatures to rise which can impact chemical contents Be aware of unusual odors vapors etc when opening the refrigerator or freezer An inventory should be posted on the refrigerator door Chemical refrigerator or freezers should be located away from laboratory exits Refrigerators and freezers should be cleaned out and manually defrosted as necessary When defrosting a freezer consideration should be taken regarding potential chemical contamination of the water If the water draining from a defrosted refrigerator may be chemically contaminated contact AOPP for further assistance 6 17 COMPRESSED GAS CYLINDER SAFETY Compressed gas storage requirements are discussed above in Section 5 7 3 However there are additional important safety requirements for use of compressed gases in laboratories detailed below Gas cylinder connections and fittings must be inspected frequently for dete
10. be similar to the diameter of the waste line there should be a tight fit between the container opening and waste line In addition a hole should be drilled to accommodate any exhaust filter or air valve tube that may be required It is recommended that either a 4 liter container or 5 gallon carboy be used for waste collection The modified cap should be replaced with a regular unmodified cap once the container is full and ready for AOPP pickup De CHEMICAL SPILLS Chemical spills in the laboratory can pose a significant risk to human health and the environment All lab personnel must be trained on how to properly respond to chemical spills in order to minimize risk In general chemical spills can be placed into one of two categories non emergency chemical spills or emergency chemical spills 67 9 1 NON EMERGENCY CHEMICAL SPILL PROCEDURES Non emergency chemical spills are generally defined as less than 1 liter do not involve a highly toxic or reactive material do not present a significant fire or environmental hazard and are not in a public area such as a hallway These spills can be cleaned up by properly trained lab personnel using conventional lab PPE e g safety glasses goggles lab coat gloves and the lab spill kits provided in each lab In general when a non emergency spill occurs in the lab the area around the spill should be isolated everyone in the lab should be made aware of the spill and the spilled material should be a
11. direct the laboratory assistants delegating responsibility as appropriate and necessary o Supervise staff as it pertains to safety and compliance in the laboratories o Provide overall direction coordination and evaluation of laboratory instructors including the Faculty Performance Appraisal process o Conduct regular one on one meetings with laboratory assistants and instructors Other Essential Job Functions In addition to the job responsibilities described above all employees of Southern California University of Health Sciences are responsible for the following essential job functions Getting along with co workers Cooperating with co workers Responding politely to customers students candidates Working as a team member Being able to think quickly and act appropriately in emergency situations Functioning under intense time pressure Working extra hours as required Continuing to perform well under pressure SCU Core Values 1 Transparency 2 Grit 3 Sense of humor SCU Permission to Play Values SCU Aspirational Values 1 Respect 1 Evidence based 2 Integrity 2 Passion 3 Emotional intelligence 3 Extra mile 4 Team player 4 Integrative 5 Accountability 5 Adaptability 6 Collegiality 7 Authenticity Common Profile Qualities 1 Customer service focused 2 Willing to invest in student client success by fostering positive relations guidance and assistance 3 A belief that no task that improves the
12. fire and or explosion has occurred or there is a threat of fire and or explosion e The large spill which is either highly toxic or presents an immediate fire or environmental hazard is in a public area such as a hallway e Toxic vapors are leaving the area where the spill has occurred such as seeping from the laboratory into the hallway or neighboring rooms e You are unsure of the hazards and feel that the spill could be harmful to building occupants Ensure that no one else is allowed to enter the area until the spill has been properly cleaned up by the local Fire Department 9 3 CHEMICAL SPILL KITS 68 Each laboratory has a spill response kit available for use Lab spill kits can either be purchased from a vendor or created by lab personnel but each spill kit should be equipped to handle small spills of the most common hazards in the laboratory Basic spill kits are provided by AOPP If you are aware of materials inside the lab that would require more sophisticated equipment contain the Lab Supervisor or the Department Chair The kit should be equipped with response and cleanup materials such as Absorbent materials such as pads booms and oil dry or kitty litter booms or pillows Neutralizing agents e g Neutrasorb for acids and or bases if high volume of acids and or bases are stored in the laboratory Containers such as drums buckets and or bags to containerize spilled material and contaminate debris generated durin
13. fit the job to the body through proper body positioning posture movement tools workplace layout and design Parts of the body commonly affected by poor ergonomics include neck shoulders back hands wrists elbows legs and feet Resources are available to improve ergonomic conditions and help reduce cumulative trauma injuries to laboratory workers Often simple adjustments are all that is required to improve conditions Contain AOPP for more information Laboratory Electrical Safety Training Laboratory employees shall be trained to understand the specific hazards associated with electrical energy Employees who need access to operate circuit breakers and fused switches in electrical panels may require additional training to be designated by their supervisor as qualified for the task Portable Electrical Equipment and Extension Cords The following requirements apply to the use of cord and plug connected equipment and flexible cord sets extension cords Extension cords may only be used to provide temporary power and must be used with Ground Fault Circuit Interrupter GFCI protection during maintenance and construction activities and in damp or wet locations Portable cord and plug connected equipment and extension cords must be visually inspected before use for external defects such as loose parts deformed and missing pins or damage to outer jacket or insulation and for possible internal damage such as pinched or crushed oute
14. for college and program level safety committees and internal self audits The IHSP provides indemnification from regulatory fines for entities with a certified safety program An IHSP certified safety program must have the following elements Regular safety committee meetings Means of communicating safety issues to the departments and or divisions in a timely manner Upper administrative support for safety Self audits checklists completed for all areas Abatement of deficiencies found during the self audits An annual safety program audit and walk through by AOPP and SO AE Recommendation for IHSP certification renewal from AOPP 2 1 CHEMICAL AND LABORATORY SAFETY COMMITTEE CHIPS SCU has established the CHiPs Committee with the responsibility to promote safe and proper chemical management at all SCU campuses and related facilities Chemical management includes but is not limited to the procurement and the safe handling use storage and disposal of chemicals CHiPs reviews lab safety programs and makes recommendations to the various Department Chairs and Deans as appropriate CHiPs consists of members selected for appointment by the Chemical Hygiene Officer and include representation from the Basic Sciences Department Division of Health Professions University Health System the Division of Professional 15 Studies as well as Physical Plant and Auxiliary Operations Although AOPP facilitates the content of the CHP it is ultima
15. glove manufacturer to ensure that the gloves you plan on using are compatible with Refer to glove selection chart from the links below http www ansellpro com download Ansell 8thEditionChemicalResistanceGuide pdf OR http www allsafetyproducts biz page 74172 OR http www showabestglove com site default aspx OR http www mapaglove com Eye Protection Click here to enter text Skin and Body Protection Click here to enter text Hygiene Measures Click here to enter text Engineering Controls Click here to enter text First Aid Procedures If inhaled Click here to enter text In case of skin contact Click here to enter text In case of eye contact 76 Click here to enter text If swallowed Click here to enter text Special Handling and Storage Requirements Click here to enter text Spill and Accident Procedure Chemical Spill Dial 911 Spill Assess the extent of danger Help contaminated or injured persons Evacuate the spill area Avoid breathing vapors If possible confine the spill to a small area using a spill kit or absorbent material Keep others from entering contaminated area e g use caution tape barriers etc Small lt 1 L If you have training you may assist in the clean up effort Use appropriate personal protective equipment and clean up material for chemical spilled Double bag spill waste in clear plastic bags label and take to the next chemical waste pic
16. likely to throw particles No loose clothing or jewelry Head impact Working or walking in area having Hard hat potential of falling tools equipment or stored items Skin eye Cryogenic liquids Splash goggles skin cover to damage elbows knees throat closed shoe easily removed socks Cryogloves for dispensing Volume gt 1 L Skin cover to throat wrists ankles Skin eye Transport of liquid nitrogen in hallways See cryogenic liquids also all damage and elevators wheeled vessels or carts must asphyxiation restrain Dewar and have wheels large body injury enough to safely traverse elevator frostbite door and scales gap Self pressurizing vessels weighing gt 100 lb gross Plus skin cover to wrists throat ankles always position blow off valve away from body Dispensing from main bulk tank All above and hearing protection Frostbite eye impact Dry ice very cold frozen solids Safety glasses insulated gloves skin cover to elbows knees throat closed shoe w socks Skin eye Hot liquid rxn mixture water bath oil Splash goggles insulated gloves skin damage bath autoclave still cover to knees elbows throat closed shoe w socks Volume gt 1 L Skin cover to throat wrists ankles emergency shower available in work area Eye damage UV radiation UV blocking goggles skin cover on all Erythema potentially exposed areas Potential face UV exposure UV face shield 80
17. off counters Specimens models are appropriately stored Scalpels and knives are cleaned and put in appropriate storage area Items for disposal are placed in the appropriate collection containers Gas valves are turned off Eye wash stations have been checked and are running properly Lab is left the way it was found All lights are turned off All classroom doors are closed and locked Anything out of the ordinary that needs to be reported or addressed Lab instructor s name Signature Lab instructor s name Signature Lab TA s name Signature 74 Appendix C Standard Operating Procedure aio here to enter chemical name or class This is an SOP template and is not complete until 1 lab specific information is entered into the box below 2 lab specific protocol procedure is added to the protocol procedure section and 3 SOP has been signed and dated by the Lab Supervisor and relevant lab personnel Print a copy and insert into your Laboratory Safety Manual and Chemical Hygiene Plan Pe HEE Click here to enter text SEH Click here to enter a date Date SOP was approved by Lab Supervisor Click here to enter a date Lab Supervisor Click here to enter text Lab Satety Coordinator Lab Instructor Piek here to enteriext Lab Phone Click here to enter text Office Phone Click here to enter text
18. safety administrator 8 Complete all required AOPP and or other mandatory safety training and provide written documentation to the laboratory supervisor 9 Participate in the AOPP managed medical surveillance program when required i e Respirator Fit Test and 10 Inform the Laboratory Supervisor Chemical Hygiene Officer or Department Chair of any work modifications ordered by a physician as a result of medical surveillance occupational injury or chemical exposure 1 7 LABORATORY SAFETY OFFICER RESPONSIBILITIES Very often it is not practical for the Laboratory Supervisor to be present in the lab on a daily basis to ensure that safe and compliant practices are being carried out by all lab staff For this reason it is highly recommended that each instructor function as a Laboratory Safety Officer to manage the daily operations of the lab s safety program The Laboratory Supervisor should empower the instructors to make decisions on daily operations involving safety and compliance including the authority to instruct other lab personnel to follow all safety procedures e g PPE use hazardous waste procedures etc Everyone involved should be familiar with how the lab operates and have demonstrated lab safety experience e g senior graduate student post doc lab manager Having instructors function as Laboratory Safety Officers in each lab provides many benefits such as 1 Other lab personnel know who to contact with questions abou
19. samples developed in the laboratory 1 All samples must be kept closed except when in use Storage in beakers or flasks should be temporary If temporarily storing samples in beakers or flasks a cork Parafilm or some other closure device must be used All samples must be labeled with the chemical name date the sample was developed received and the name of generator 49 4 Chemical structure or a labeling system that is only known to lab personnel is not acceptable as the only means of labeling samples Acronyms can be used as a labeling system as long as an up to date legend is posted in the lab 5 Samples should be disposed of within 6 months unless actively being used for analysis Stockpiling unusable samples in not an acceptable practice All samples that are no longer necessary must be properly disposed of in a timely manner using AOPP s hazardous waste program 6 Samples must be stored according to the primary hazard class this should be done to the best of your ability considering the properties that are known or assumed such as toxicity If the hazard s of a sample are unknown the Laboratory Supervisor must attempt to determine whether it is hazardous or not Assume all samples are toxic unless otherwise demonstrated This can be accomplished by literature review or reviewing the hazards of other similar compounds At a minimum the Laboratory Supervisor should be able to determine if a chemical is flammable corrosiv
20. the grounding prong from an electrical plug is prohibited Flexible cords may only be plugged into grounded receptacles Adapters that interrupt the continuity of the equipment grounding connection may not be used All portable electric equipment and flexible cords used in highly conductive work locations such as those with water or other conductive liquids or in places where employees are likely to contact water or conductive liquids must be approved for those locations Employee s hands must be dry when plugging and unplugging flexible cords and cord and plug connected equipment if energized equipment is involved If the connection could provide a conducting path to the employee s hands e g if a cord connector is wet from being immersed in water the energized plug and receptacle connections must be handled only with insulating protective equipment Lamps for general illumination must be protected from breakage and metal shell sockets must be grounded Temporary lights must not be suspended by their cords unless they have been designed for this purpose Extension cords are considered to be temporary wiring and must also comply with the section on Requirements for Temporary Wiring in this program All use of extension cords must be approved by Physical Plant Management Temporary Wiring Requirements Temporary electrical power and lighting installations 600 volts or less including flexible cords cables and extension co
21. them and wearing the appropriate PPE while inside a lab environment 8 Gaining prior approval from the Pl Laboratory Supervisor for the use of restricted chemicals and other materials 9 Consulting with Laboratory Supervisor Chemical Hygiene Officer of Department Chair before using particularly hazardous substances PHS explosives and other highly hazardous materials or conducting certain higher risk experimental procedures 10 Immediately reporting all accidents and unsafe conditions to the Pl Laboratory Supervisor 11 Completing all required health safety and environmental training and providing written documentation to their supervisor 12 Participating in the medical surveillance program when required 13 Informing the Laboratory Supervisor of any work modifications ordered by a physician as a result of medical surveillance occupational injury or exposure and when working autonomously or performing independent research or work SCU does not encourage autonomous laboratory research at a minimum one other trained individual should be present 14 Reviewing the plan or scope of work for their proposed research with the Laboratory Supervisor or Department Chair 11 15 Notifying in writing and consulting with the Laboratory Supervisor or Department Chair in advance if they intend to significantly deviate from previously reviewed procedures Note Significant change may include but is not limited to change in the objectiv
22. Biol gical EK Lg EE 24 4 4 Radioactive Material Hazards cccsscccciicsescccisescceascepsndcevsccebonouscsivesscsaicosaseadvebsgcueeuslscudvendieascnsceudisosdoanadeae 24 4 5 Laser Hazal EE 24 5 Laboratory Satety Controls ie E E E E NEE Ge Re REG ee ee 24 5 1 Engineering Controls and Safety Equipment ccceccessscecececeeseseececeeeceeseeeeeseeeescseeaeseeeesceeseaaeeeeeeseeeee 25 ME Chemical F me Hoods RE ARE OR TOO 25 SLA Ee EE EE EE EE EE OE ER EG 27 5 1 3 Laminar Flow Clean Benches AAA 28 5 1 4 Biological Safety Cabinets BSC se ee ee ee ee e a ee Re ee ee Re ee ee ee ee ee ee ee ee 29 5 1 6 Safety Showers and Eyewash Station St sesse EERS Ke de EE A EO Re ek ee gee eg ea Ee N Seed 29 517 A TH gl 29 5 18 He DO ati EE EE RE EE 30 54 9 Administrative CONtOls ni A A AAA 30 5 1 10 Standard Operating Proceduress SOPS ccccssccscsssscceesececsssceceessesecsessececssseceesaeeeceasececsssseceesaeeeeseaaess 30 5 1 11 Required Laboratory Posting SE ie EER Ke ds 31 5 1 12 Personal Protective Equipment DPE 31 6 Laboratory Management Plan 32 6 1 Laboratory Safety Guidelines Se SEE Ee SS Ee n ded SE EE ee eg Ge Se EN de Ge ee see de Go es Ge Ne ee de oe n Ee GE de Pe ge 32 6 2 Laboratory Safety QUESTIONS iis se ee ee Se Ee ee AA GE Ge Ee Re ee AA Ge Ge Ee ke AA ee ER Re AA ee ee ee ee ee niTer t ee ee 32 6 3 General Laboratory Safety RuleS esse ss se ee ee ee Ge ee ee Ge Ge ee ee ee Ee Re ee Ge ee ee ee ee Re ee ee ee
23. EPA Environmental Protection Agency GFCI Ground Fault Circuit Interrupter GHS Globally Harmonized System of Classification and Labeling of Chemicals HBr Hydrogen Bromide HF Hydrofluoric Acid HEPA High Efficiency Particulate Air HPLC High Performance Liquid Chromatography LC Liquid Chromatography LC50 Lethal Concentration 50 LD50 Lethal Dose 50 LEL Lower Explosive Limit LSC Laser Safety Committee MSDS Material Safety Data Sheet NFPA National Fire Protection Association OSHA Occupational Safety and Health Administration PCB Polychlorinated Biphenyl PHS Particularly Hazardous Substance PI Principal Investigator PPE Personal Protective Equipment RCRA Resource Conservation and Recovery Act rDNA Recombinant Deoxyribonucleic Acid REM Radiological and Environmental Management RSC Radiation Safety Committee SAA Satellite Accumulation Area SDS Safety Data Sheet SOP Standard Operating Procedure UEL Upper Explosive limit 8 di INTRODUCTION Laboratory safety is an integral part of laboratory research and is essential to ensure that Southern California University of Health Sciences SCU s compliance with all applicable environmental health and safety laws regulations and requirements are met The risks associated with laboratory research workplace injuries environmental incidents and property losses or damage are greatly reduced or eliminated when proper precautions and practices are observed
24. Ee ae 44 6 20 Sharps Handling Satety si es ESE ER voce indian GE eege tha e Sune Ee ge e se ede Ene ee DR 44 6 21 Equipment Apparatus and Instrument Safer 45 Laboratory PPEPOl NY a ies 54 7 1 Haza ASS Mii a or 55 7 2 Task Evaluation Hazard Assessment ee esse ee ee ee se ee ee ee Ge ee GR ee ee GR ee ee ee be Ge ee ee ee ee ee ee ee ee ee ee be ee 55 7 3 Location Evaluation Hazard Assessment sesse esse ee ee ee ee ee ee ee ee Ge AR ee Ge AR ee Ge ee ee ee ee ee ee ee be ee 55 7 4 Job Title Evaluation Hazard Assessment esse ees ees se ee ee ee ge ee ee ee Ge nono ee Ge ee GR be ran nc non nn ee ee ee nan ee ee ee ee be ee 56 7 5 Minimum PPE Requirements for Laboratories iss see esse se se Ee ee ee ee ee ee Ee ee ee Ge ee ee ee ee ee ee 56 Hazardous Waste Management is a a e tone Re GE AE ed ge See es Gee Ee N eek Ne beg sents 60 8 1 Waste Identification and Labeling se ee se Ee ee AE ER ee AA Ge Ge ee ee AR ER Re ee AA Ge Ee ke AA ee ee ke ee ee 61 8 2 Waste Storage Requirements is ese ike ne ek kee ee be Sek bes ewe kg Ge ee be eek kg ek dk sewe Ene ek Ne ene gedet 62 8 3 Waste OR Fal DEER iio ei suerte ee EE ee Ge EE 62 8 4 Waste Disposal ProcedureS ees es se ee ee Ee Ee Ee Re AA Ge Ge ee ee AA Ge Ge Ee Re ee ee ee ee Re ee AR Ee ke ee ee ee ee ke ee ee 63 8 5 Vd ale ide sl AG EDE OE ER OE EE EE N EEN 63 8 5 1 Labeling Unknown Chemicals is se ee Ee Ee ee AE Ge Ee Ee AA GE Ge Re ee Ee ee ee AE ee RA ee ee Ge ee ee ee e
25. REGATION All chemicals must be stored according to chemical compatibility Once segregated by chemical compatibility they can then be stored alphabetically Information regarding chemical compatibility can be found in the SDS primarily in Section 7 Handling and Storage and Section 10 Stability and Reactivity If unsure of proper segregation procedures contact the Laboratory Supervisor for assistance Chemical segregation can be achieved by either isolation e g organic solvents stored in a flammable cabinet physical distance e g acids and bases are stored on opposite sides of a chemical storage room or secondary containment e g placing oxidizing acids such as nitric acid into a secondary containment to segregate from organic acids such as formic acid as shown in Figure 6 7 In the most general terms proper segregation can be achieved by e Storing acids away from bases and toxics e Storing oxidizers away from organic chemicals and Table 6 1 Chemical Compatibility Chart Storing reactive and acutely toxic materials away from all other chemicals 36 Table 6 1 illustrates a more detailed chemical compatibility logic that can be used for chemical storage Hazard classes marked by an X need to be segregated from each other e g Acid inorganic must be segregated from Base inorganic Contact the Laboratory Supervisor with questions regarding chemical segregation Acid Ac
26. University is beneath us servant leadership 4 Be an ambassador of the brand 5 Be a part of recruitment 6 Resource innovator Profile Specific Qualities 1 An understanding of SCU history 2 Excellent communication skills 3 Strategic community and external perspective 4 Support philanthropic endeavors 5 Connect engage and give minimum alumni member and University Partner 6 Self reflection reflective practitioner 7 Ability to utilize transformational leadership 8 Able to maintain confidentiality 9 Able to engage in constructive conflict 10 Models professional leadership 11 Be champions of the University mission vision amp values 12 Strategic oversight of their area and assigned initiative 72 13 Demonstrate commitment to promoting amp enhancing diversity in all forms 14 Seize initiative where required 15 Bring best ideas amp perspectives to issues of importance for the good of SCU 16 Individually and collectively prepared for substantive conversations 17 Forge partnerships in conjunction with their supervisor 18 Civic engagement 19 Constructive support for each other amp SCU 20 Innovation Continuous Improvements Assessments 21 Build and participate in campus community 22 Good organizational skills Additional Qualities for Academic Leaders 1 Exemplar scholars teachers and practitioners 2 Student advocate 3 Proficient in student assessment academic program review and r
27. YSICAL PLANT DEPARTMENT The Auxiliary Operations Physical Plant Department AOPP has numerous roles at SCU and serves as the environmental health and safety department for the University One of AOPP s roles is to manage regulatory compliance with all federal state and SCU regulations involving environmental health and safety issues AOPP facilitates a number of programs that apply to laboratory safety a few of which include biological safety laser safety personal protective equipment program radiation safety development of standard operating procedures as well as the CHP AOPP also performs numerous safety inspections of facilities throughout the year to monitor compliance with regulatory requirements AOPP provides a variety of services such as training chemical biological and radioactive waste pickups and safety consultation AOPP does not operate under a specific college or educational department of the University rather AOPP reports directly to the University Administration via the Vice President for Administration and Finance 2 INTEGRATED HEALTH amp SAFETY PLAN IHSP It is the policy of SCU to integrate environmental health and safety into all operations The IHSP is SCU s safety program which is facilitated by AOPP and was developed to provide a framework for laboratories to comply with environmental health and safety EHS regulations The IHSP assists in communication of EHS issues across the organization and calls
28. Yscu SOUTHERN CALIFORNIA UNIVERSITY OF HEALTH SCIENCES CHEMICAL HYGIENE PLAN 8 HAZARDOUS MATERIALS SAFETY MANUAL Prepared By Alta Environmental 3777 Long Beach Blvd Long Beach CA 90807 562 495 5777 www altaenviron com 8 Auxiliary Operations amp Physical Plant Southern California University of Health Sciences This is the Chemical Hygiene Plan specific to the following areas Building s Room Number s L 90 L 120 E 80 E 120 M 90 University Health Center Hayward Satellite Campus Chemical Hygiene Officer Executive Director of Auxiliary Operations Physical Plant Laboratory Supervisor Chief Laboratory Technician see Appendix A for Job Description Department s College of Science Integrated Health Los Angeles College of Chiropractic College of Eastern Medicine University Health System and Auxiliary Operations and Physical Plant Revised Must be reviewed at least annually by Executive Director of Auxiliary Operations and Physical Plant 12 29 2014 Important Telephone Numbers 1 911 for All Emergencies 2 Local Fire Department Station 15 562 943 4537 Non Emergency Line 3 Local Police Department Norwalk Sheriff 562 863 8711 Non Emergency Line 4 SCU Campus Safety Department 562 902 3333 Do Not Use for an Emergency 5 SCU Auxiliary Operations amp Physical Plant 562 947 8755x515 Do Not Use for an Emergency All laboratory chemical use areas must maintain a work
29. aboratories Compressed gas cylinders cylinders must be stored in a secure well ventilated location and in an upright position at all times All cylinders should be handled as if full and should never be completely emptied Cylinders that are not in use meaning that the cap is on must be secured and have the safety cap Multiple cylinders may be secured together gang chained only if they are capped not in use Only capped cylinders can be secured with a single restraining device gang chained as shown in Figure 6 3 Cylinders that are in use meaning there is a regulator attached must be individually secured by a chain or strap as shown in Figure 6 4 Cylinder valves and regulators should be protected from impact or damage Figure 6 3 Not In Use Cylinders Figure 6 4 In Use Cylinders 39 6 12 REACTIVE MATERIALS STORAGE Reactive materials include explosives pyrophorics self heating and self reacting compounds and water reactive Many reactive materials are also toxic and are dissolved or immersed in a flammable solvent e g lithium alkyl compounds dissolved in diethyl ether sodium metal immersed in mineral oil Other common hazards often associated with reactive chemicals include corrosivity teratogenicity or organic peroxide formation The following guidelines for storing reactive materials must be followed in all laboratories The amount of reactive materials stored in the lab must be kept to a minimum Any e
30. an result in an implosion and the possible hazards of flying glass splattering chemicals and fire All vacuum operations must be set up and operated with careful consideration of the potential risks The following guidelines should be followed when using vacuum apparatus in the laboratory 48 Do not allow water solvents or corrosive gases to be drawn into vacuum systems Protect pumps with cold traps and vent their exhaust into an exhaust hood Assemble vacuum apparatus in a manner that avoids strain particularly to the neck of the flask Avoid putting pressure on a vacuum line to prevent stopcocks from popping out or glass apparatus from exploding Place vacuum apparatus in such a way that the possibility of being accidentally hit is minimized If necessary place transparent plastic around it to prevent injury from flying glass in case of an explosion When using a rotary evaporator the glass components of the rotary evaporator should be made of Pyrex or similar glass Glass vessels should be completely enclosed in a shield to guard against flying glass should the components implode Increase in rotation speed and application of vacuum to the flask whose solvent is to be evaporated should be gradual When using a vacuum source it is important to place a trap between the experimental apparatus and the vacuum source The vacuum trap protects the pump and the piping from the potentially damaging effects of the material protects peo
31. are standard phrases assigned to a hazard class and category that describe the nature of the hazard and e Precautionary statements are recommended measures that should be taken to minimize or prevent adverse effects resulting from exposure to the hazardous chemical GHS also standardizes the hazard pictograms that are to be used on all hazard labels and SDSs There are 9 pictograms that represent several defined hazards and include the harmonized hazard symbols which are intended to convey specific information about each hazard Figure 3 2 2 illustrates these GHS hazard pictograms 18 Carcinogen Respiratory Sensitizer Reproductive Toxicity Target Organ Toxicity Mutagenicity Flammable Pyrophoric Self Irritant Dermal Sensitizer Heating Emits Flammable Gas Acute Toxicity harmful Organic Peroxide Narcotic Effects Explosive Organic Peroxide Self Reactive Environmental Toxicity Acute Toxicity Severe Figure 3 2 GHS Hazard Pictograms GHS labeling requirements are only applicable to chemical manufacturers distributors and shippers of chemicals GHS labeling requirements are not required for chemicals being stored in a laboratory However since most chemicals stored in the laboratory have been purchased from a chemical manufacturer the GHS labeling and pictogram requirements are very relevant and must be understood by laboratory employees By the end of calendar year 2015 SCU will have fully adopted the GHS syste
32. area specific Chemical Hygiene Plan which conforms to the requirements of the OSHA Occupational Exposure to Hazardous Chemicals in Laboratories 29 CFR 1910 1450 SCU laboratories may use this document as a starting point for creating their work area specific Chemical Hygiene Plan Minimally this cover page is to be edited for work area specificity and the SCU Chemical Hygiene Plan Awareness Certification Form must be completed for all lab employees This instruction and information text should remain This model Chemical Hygiene Plan is the 2014 version 1 INTO Lg LTE 8 1 1 PUDO EE 8 1 2 o E 8 1 3 GHP USEINStrUCTIONS SR EE EE OR OR OE Er Ea 9 1 4 Employee Rights and ResponsibilitieS is sees es se Ee ee AR ER Re AA ee ee AA AR Ee ee ee ee ee ee ee Ge ee 9 1 5 Laboratory Supervisor Responsibilities see esse ss se se ee ee Ge Ge Ee Re ee ee Ge ER ee AA ee ee ee ee Ge ee ee ee ee ee ee 11 1 6 Laboratory Employee Responsibilities is see ees es se Ee ee ee Ee Re ee ee Ee Re ee ee ee ee ee Ge ee ee ee ee ee ee 12 1 7 Laboratory Safety Officer Responsibilities esse ss se se ee Ge Ee Ee Re ee Ee ee AA ee Ee ee ee Ge ee ee ee ee ee ee 12 1 8 Non Laboratory Personnel Support Staff Responsibilities iese esse es ee Re ee ee RR ee ee RR ee ee RA ee be ee 13 1 9 Chemical Hygiene Officer Responsibilities ese ss ses se ee ee ee ee Ee Re ee ee Ee Re ee Ge Ge Ee ee ee ee ee ee ee ee ee 13 1 10 Auxiliary Operations Phy
33. awn hood sash or blast shield b c Corrosive pH 12 or pH lt 2 5 d Toxic having any poisonous or irritating effects to human tissue or human health e Chemical resistant gloves glove thickness length and material must be chosen carefully and will be specific to the chemicals mixtures used and the process conditions f Hood 100 exhaust to outside current approval for all work and functioning properly g Chemicals requiring designated areas full list is at http www purdue edu rem home booklets crdalist pdf Tab1 Specific Standard Operating Procedures Tab 2 Lab Specific Protocols Requirements Rules Tab 3 Lab Specific Hazard Assessments
34. be either acidic or basic caustic The best storage method for corrosive materials is inside of a corrosive storage cabinet or lab cabinet where acids and bases are segregated at all times Acids must also be segregated from chemicals where a toxic gas would be generated upon contact with an acid e g reactive cyanide compounds Organic acids e g acetic acid formic acid must be stored away from oxidizing acids e g nitric acid perchloric acid as these types of acids are incompatible with each other Segregation can be achieved either by physical distance preferred method or by secondary containment as shown in Figure 6 6 41 Figure 6 6 Chemical Segregation Using Secondary Containment 6 15 OXIDIZERS AND ORGANIC PEROXIDE STORAGE Oxidizing materials are defined as substances which while in itself are not necessarily combustible may generally by yielding oxygen cause or contribute to the combustion of other material An organic peroxide is an organic substance which contains the bivalent O O structure and may be considered a derivative of hydrogen peroxide where one or both of the hydrogen atoms have been replaced by organic radicals The following guidelines for storing oxidizers and organic peroxides must be followed in all laboratories Oxidizers e g hydrogen peroxide sodium nitrate and organic peroxides e g methyl ethyl ketone peroxide benzoyl peroxide must be stored in a cool dry location and kept away from c
35. ble to their work and to adhere to them 4 4 RADIOACTIVE MATERIAL HAZARDS Radioactive Hazards are those involving radioactive material and radiation producing devices The Chair of Diagnostic Imaging must directly submit to the Chemical Hygiene Officer an application to use radioactive material or radiation producing devices Use of radioactive materials requires a license issued by the US Nuclear Regulatory Commission or a registration with the California State Department of Health and all work must comply with applicable regulations Prior to application for licensure the proposed usage of radioactive material will first be vetted through CHiPs 4 5 LASER HAZARDS Laser hazards involve laser radiation devices The Lab Supervisor must submit to the Chemical Hygiene Officer an application to use Class 3B and Class 4 lasers or laser devices The use of lasers is subject to OSHA regulations and utilizes current ANSI standards to develop guidance and will first be vetted through CHiPs prior to being adopted for laboratory usage 5 LABORATORY SAFETY CONTROLS 25 Laboratory safety controls include engineering controls administrative controls and PPE Elements of these three categories should be used in a layered approach to minimize employee exposure to hazardous chemicals There are four primary routes of exposure in which hazardous substances can enter the body 1 inhalation 2 absorption 3 ingestion 4 injection Of these the mos
36. bsorbed and collected using either pads or some other absorbent material such as oil dry or kitty litter Decontamination of the spill area should be conducted using an appropriate solvent soap and water is often the most effective Proper PPE should be worn at all times and only trained personnel should conduct the cleanup Additionally review the SDS s specifically Section 6 Accidental Release Measures to obtain chemical specific cleanup information 9 2 EMERGENCY CHEMICAL SPILL PROCEDURES Emergency chemical spills are generally defined as greater than 1 liter involve a highly toxic or reactive compound present an immediate fire or environmental hazard or require additional PPE e g respirator and specialized training to properly cleanup The following procedures should be followed in the event of an emergency chemical spill Cease all activities and immediately evacuate the affected area make sure that all personnel in the area are aware of the spill and also evacuate If chemical exposure has occurred to the skin or eyes the affected personnel should be taken to the nearest safety shower and eyewash station Dial 911 which will initiate both the local Police and Fire Department response if the situation is or could become an emergency e g chemical exposure has occurred a fire or explosion has occurred The fire alarm should be pulled which will initiate building evacuation if any of the following occurs e A
37. cation 56 within the lab where it is easily accessed by personnel e g posted near the front door of the lab If employees perform specific tasks not covered by the laboratory hazard assessment then it will be necessary to perform another type of hazard assessment such as the task evaluation assessment that does address the specific hazards of that task The following describes the steps that should be taken to perform a task evaluation hazard assessment e Identify the hazards e List each task where hazard is present e Determine PPE requirements for each task e List other control measures required engineering and administrative controls 7 4 JOB TITLE EVALUATION HAZARD ASSESSMENT Job title evaluation hazard assessments should be conducted for specific positions These types of hazard assessments should be written in a comprehensive manner that includes the majority of hazards that a specific job position e g Animal Care Technician routinely encounters during the normal course of work This type of hazard assessment is commonly used for positions where the hazards encountered do not frequently change If the employee encounters a hazard that is not covered by the job title evaluation hazard assessment then it will be necessary to perform another type of hazard assessment such as the task evaluation hazard assessment that does address the specific hazards of that task The following describes the steps that should be taken to perform
38. ctices for using and handling compressed gas that may be associated with working in the glove box All equipment and chemicals in the glove box must be organized and all chemicals must be labeled Do not allow items particularly chemicals to accumulate in the glove box 5 1 3 LAMINAR FLOW CLEAN BENCHES 29 A laminar flow clean bench is an enclosed bench designed to prevent contamination of semiconductor wafers samples or any particle sensitive device Air is drawn through a filter and blown in a very smooth laminar flow towards the user Therefore it is critical that absolutely no hazardous chemicals infectious and or radioactive materials ever be used in a laminar flow clean bench as the vapors are blown directly towards the user Applications that involve the use of chemicals should be conducted in chemical fume hoods 5 1 4 BIOLOGICAL SAFETY CABINETS BSC A biological or biosafety safety cabinet is an enclosed ventilated laboratory workspace for safely working with materials contaminated with or potentially contaminated with infectious materials The primary purpose of a biosafety cabinet is to serve as a means to protect the laboratory worker and the surrounding environment from pathogens All exhaust air is filtered as it exits the biosafety cabinet removing harmful particles Biological safety cabinets are not designed to be used with chemical applications so the use of chemicals should be kept to a minimum Applications that
39. d in Section 14 of GHS formatted SDSs The DOT 9 hazard classes are illustrated below in Figure 3 5 It should be noted that Figure 3 5 only lists the primary hazard classes the sub classes e g Organic Peroxides DOT Class 5 2 were omitted for stylistic purposes 22 em NON FLAMMABLE GAS KR DOT dass 4 DOT Class 5 DOT Cass 6 Hammiable Solids Oxidizers Poisons CORROSIVE d i 4 J ag A Y ho DOT Gass 7 DOT Class 8 DOT Gass 9 Radioactive Materials Corrosives Miscellaneous Figure 3 5 NFPA Hazard Rating System 4 CLASSES OF HAZARDOUS CHEMICALS Chemicals can be divided into several different hazard classes The hazard class provides information to help determine how a chemical can be safely stored and handled Each chemical container whether supplied by a chemical manufacturer or produced in the laboratory must have a label that clearly identifies the chemical constituents In addition to a specific chemical label more comprehensive hazard information can be found by referencing the SDS for that chemical The OSHA Laboratory Standard defines a hazardous chemical as any element chemical compound or mixture of elements and or compounds which is a physical or health hazard This definition of a hazardous chemical and the GHS primary classes of chemicals are briefly discussed below 4 1 PHYSICAL HAZARDS A chemical is a physical hazard if there is scientifically valid evidence that it is flammable combustible compres
40. e oxidant or reactive If samples are consolidated for storage e g vial boxes it is not always necessary to label every sample container For example a box containing sample vials which are all in the same hazard class e g miscellaneous pharmaceutical compounds considered to be toxic can have one label on the outside of the box stating Miscellaneous Toxic Pharmaceutical Compounds or a similar description A label such as the one shown in Figure 5 9 can be used to identify consolidated samples and should only be used on a temporary basis This type of information communicates the hazards to emergency responders as well as gives AOPP the information necessary for proper disposal If the chemical substance is produced for another user outside of the lab the Laboratory Supervisor must comply with the Hazard Communication Standard including the requirements for preparation of SDSs and container labeling Transporting Hazardous Chemicals Transporting chemicals is a potentially hazardous process that must be done properly to avoid accidents and potential injuries The following subsections discuss how to properly ship chemical off campus using a shipping company how to transport chemicals on campus using a SCU owned vehicle and how to safely move chemicals by foot across campus Shipping Hazardous Chemicals off Campus Shipping chemicals research samples or other similar materials off campus is potentially regulated by the Departme
41. e ee 63 8 5 2 Identifying Unknown Chemicals sees es se se ee AE Ge Ee ee AA GE Ge ee ee ee Ee ee ee ee ee ee ee ee Ge Ee ke ee ee ee ee 64 8 5 3 Removing Unknown Chemicals from the Work Area eise se ee ee ee ee ee ee ee ee ee Ge ee ee ee ee ee 64 8 5 4 Preventing Unknown Chemicals sees se Ee ee AE GR Ee ee EA AR Ge ee ee Ee ee ee AE ee RA ee ee ee ee ee ee ee ee 64 8 6 Sinksand Trash Disposal ESE KERE A Ve Ee Ge Se sae Re does ER DER Ee ER ee ee ee ee Ge DE RD hd 65 8 7 OO EDE EA EE OE OE 65 8 8 Liquid Chromatography Waste sesse se se ee a Ee Re ee ee Ee Re ee E Ee Ee Re ee Ee ee ee Ge ee E ee ee ee 65 le Bel EE HE EE cadets EO ER OE EE N N 66 9 1 Non Emergency Chemical Spill Procedures iese iss se se ee ee Ee Re Ee ER Re ee Ee ee ee ee ee ee ee ee ee ee 67 9 2 Emergency Chemical Spill Procedures se ees es Ee Ee Re ee Ee Re ER Re ee Ee ee ee Ge ee ee ee ee ee ee 67 9 3 ele Eed EER E e N N RE EE 67 9 4 He Hut 68 10 s LR 68 10 1 BREED REES EE dE 69 10 2 S Ok III 69 CHP Document Acronyms List ANSI American National Standards Institute AOPP Auxiliary Operations Physical Plant ASTM American Society of Testing and Materials CFR Code of Federal Regulations CHO Chemical Hygiene Officer CHP Chemical Hygiene Plan CHiPs Chemical Hygiene Implementation Committee CLSC Chemical and Laboratory Safety Committee DOT Department of Transportation EHS Environmental Health and Safety
42. ed properly fire explosion and or personnel exposure can result A few common chemicals distilled in laboratories include tetrahydrofuran methylene chloride diethyl ether toluene dimethylformamide benzene and hexanes The guidelines below should be followed while thermal distillation of organic solvents is conducted in the lab 1 The thermal solvent distillation system should be installed inside of a chemical fume hood if possible 2 Ensure that all heat generating equipment has a shut off device installed 47 Ensure that all water connections on the condenser are clamped securely Inspect all glassware for defects before setting them up in the experiment Keep all air and water sensitive drying agents under inert atmosphere Make consistent efforts to not store or use other flammable or hazardous chemicals inside the fume hood where distillation is taking place Laboratory Glassware Broken laboratory glassware is dangerous Glassware related injuries ranging from small cuts to multiple stitches and eye damage are common to lab workers In order to reduce the risk of accidents the following guidelines should be followed 1 Temperature changes can shatter any laboratory glassware Never flash cool glassware with cold water especially after autoclaving or exposure to any high temperatures Only round bottomed or thick walled e g Pyrex evacuated reaction vessels specifically designed for operations at reduced pressure
43. ee 32 6 4 ales AE OE OS EE N ER N EE OE OE SEE OE 33 6 5 Chemical Inventories ss ee ee Ge ee N A ee ee ee salle A A a EEE Ge Pe 34 6 6 SCHEER EE RE 34 6 7 Chemical Labeling Redguirements sesse se ee ee ee ee AE Ge ee ee ee Ee Re ee ee Ee ee ee ee ee ee ee ee ee 35 6 8 Chemical SegregatiON EE EE A A DERE E Lae ee ee 35 6 9 Chemical Storage ReduirementS sees ss se ee ee Ge ee ee AE Ge RA ee Ge Ge Ee Re ee ee Ge ee ee ee ee ee ee ee ee 36 6 10 Geri ral Chemical StOraBe Ee SE EE EE e ER be Ee A ee d Eed ee 36 6 11 Flammable Liquids Storage eie se se ee ee Ge ER AA AE Ge ee ee AA Ge Ge ee EEE E EEE ee ee ee ee ee ee ai ee ee 37 6 12 Reactive Materials Storage ESE Se Re Ak ee 39 6 13 Acutely Toxic Materials Storage ees se ee ee a GE Ge ee a Ge Ee Re ee ee ee ee a Ge Ee aa Eia Ee ke ee ee 40 6 14 Corrosive Materials Storage c ccccccccssssscccececseseaeeecececseeesaeseeececeeseeaeseeeeeceeseeaeeeeeesceeesaeseseesceesesasaeseeeeeeees 40 6 15 Oxidizers and Organic Peroxide Storage ccccessssccccecseseeesecececsesesaesececsceeseeaesesececeesesassecececeeseaaeaeseeeceeses 41 6 16 Refrigerators and Freezers Chemical Storage occcccononoonconcnnnononnnnnncnnnnnnnnononnnncnnnnnonnnnnnncnnnnnnonnnnncnninnnns 41 6 17 Gompressed Gas Cylinder Safety EE EE 42 6 18 Cryogenic Liddids Safety A A en Se EE ee ve BEE Ee ee ed Ge ge N ee EE 43 6 19 Nanoparticle Satety EE EG ED Re Re Ge ei RE Ee Ee sauces las Ge ee GR EG SO Ge Ee De Ge
44. egional and professional accreditation JOB SPECIFICATIONS Master s degree M A or equivalent doctorate in related field EDUCATION preferred or at least 5 years related experience and or training or equivalent combination of education and experience EXPERIENCE e Atleast five 5 years of successful teaching experience or equivalent in an accredited institute of higher education e Track record of scholarly production e Excellent PC skills in a Windows OS environment proficiency TECHNICAL with Microsoft Office applications including Word Excel PowerPoint e Strong organizational skills detail oriented and accurate with ABILITIES ability to multi task excellent communication and customer service skills and ability to think and act strategically Last updated 07 14 73 Appendix B Lab Checklist Reminder Report any injuries to Security immediately at EXT 333 and notify the College of Science and Integrative Health Today s Date Lab Room Number Please check the box after each item is completed If not applicable for your lab please write N A All chemicals are stored in the appropriate cabinets All secondary containers are appropriately labeled per the Chemical Hygiene Plan Tools equipment are stored in cabinets All chemical cabinets are locked Counters have been wiped down with 70 ethanol Lab supplies miscellaneous papers have been cleared
45. em is a common way to identify chemical hazards and should be understood by laboratory employees The NFPA 704 numerical rating system is based on a O 4 system O meaning no hazard and 4 meaning the most hazardous note this in contrast to the GHS system where 1 is the most hazardous and 4 is the least hazardous Figure 3 4 illustrates the NFPA hazard rating system and identifies both the hazard categories and hazard rating system 21 Fire Hazard Health Hazard Reactivity Hazard ACID Specific Hazard Health Hazard Fire Hazard Reactivity Hazard Specific Hazard 4 Deadly 4 FP lt 73 F 4 May Detonate ACID Acid 3 Extreme Danger 3 FP lt 100 F 3 Shock Heat May ALK Alkali 2 Hazardous 2 100 F lt FP lt 200 F Detonate COR Corrosive 1 Slightly Hazardous 1 FP gt 200 F 2 Violent Chemical AA 0 Normal Material O Will Not Burn Change Va 1 Unstable if Heated FP Flash Point 0 Stable No Water Radioactive Figure 3 4 NFPA Hazard Rating System 3 5 DEPARTMENT OF TRANSPORTATION DOT HAZARD CLASSES The DOT regulates the transportation of all hazardous materials in the United States All hazardous chemicals must be properly labeled by the chemical manufacturer or distributor before transportation occurs Chemical containers stored in laboratories are not required to be labeled per DOT standards however the DOT 9 hazard classes are often seen on chemical containers and are discusse
46. em to ensure that all faculty staff and students properly dispose of hazardous waste including unwanted research samples before employees leave 8 6 SINK AND TRASH DISPOSAL No chemical waste should be poured down the drain or discarded in the trash unless it is certain that doing so does not violate hazardous waste regulations In order to ensure improper disposal does not occur please consult the relevant SDS or contact AOPP for further information regarding non hazardous chemical waste disposal 8 7 SHARPS WASTE Sharps are items capable of puncturing cutting or abrading the skin such as glass or plastic pipettes broken glass test tubes petri dishes razor blades needles and syringes with needles Sharps waste contaminated with hazardous chemicals must be placed into puncture resistant containers e g sharps container plastic or metal container with lid and properly labeled All chemically contaminated waste should be inventoried on and a request for a Hazardous Materials Pickup should be sent to AOPP for proper disposal Clean uncontaminated broken glassware and plastic sharps should be placed in a corrugated cardboard box or other strong disposable container Do not exceed 20 pounds When ready for disposal the box should be taped shut and prominently labeled as Sharp Objects Glass Discard or similar wording The Safe for Disposal should also be affixed to the outside of the container Contact AOPP for specific
47. employee must use appropriate eye and face protection equipment when exposed to hazards from chemical splash flying debris or other exposures that may occur in the laboratory Safety glasses must be worn at all times by all individuals that are occupying the laboratory area Splash proof safety goggles and or a face shield may be more appropriate depending on the type of work being performed e g transferring hazardous liquids outside of a chemical fume hood or glove box All eye protection equipment must be American National Standards Institute ANSI approved and appropriate for the work being done Eye and face protection may sometimes not be required in the lab if the employee is sitting at a workstation or desk that is away from chemical processes e g working at a desktop computer having a lab meeting at a table away from hazardous operations Hand Protection Each affected employee must wear appropriate hand protection when their hands may be exposed to skin contact of hazardous chemicals cuts abrasions punctures or harmful temperature extremes Chemical resistant gloves must be worn while handling any hazardous chemical container regardless of whether the container is open or closed it should be assumed that all chemical containers are contaminated When selecting appropriate gloves it is important to evaluate the effectiveness of the glove type to the specific hazardous chemical being handled Some gloves are more suitable for cer
48. ents should be removed and stored in a safe location outside the chemical fume hood Chemical fume hoods used for experimental work should not be used for chemical or material storage Chemical fume hoods are never to be used for chemical storage No experimental work should be conducted in storage chemical fume hoods All chemical containers used in chemical fume hoods including secondary containers e g beakers flasks reaction vessels vials etc must be labeled If is not practical to label a secondary container that is in process e g reaction vessel flask a temporary label can be used as shown in Section 5 7 of the CHP Reaction vessels in chemical fume hoods must be labeled as well If labeling the vessel itself is not practical the hood sash or wall may be labeled as illustrated in Figure 5 2 27 Figure 5 2 Alternative Labeling of Chemical Fume Hood Reaction Vessels e Do not allow the vents or air flow baffles to be blocked e Never put your head inside of an operating chemical fume hood e All chemical fume hoods should be routinely checked for airflow by measuring the face velocity which should be between 70 125 feet per minute 5 1 2 GLOVE BOXES A glove box as illustrated in Figure 5 3 is a sealed container that is designed to allow one to handle material in a defined atmosphere typically inert Glove boxes can be used to protect sensitive items inside or the user on the outside or both The following rec
49. es change in the duration quantity frequency temperature or location increase or change in PPE and reduction or elimination of engineering controls SCU does not under normal reasonable circumstances allow for deviations of this nature except when they are linked directly to an enhanced level of personal safety 16 Preparing SOPs and performing literature searches relevant to safety and health that are appropriate for their work and providing appropriate oversight training and safety information to laboratory or other personnel they supervise or direct More stringent rules may apply to an individual based upon their role within the lab environment see additional responsibilities provided within this chapter 1 5 LABORATORY SUPERVISOR RESPONSIBILITIES The Laboratory Supervisor is the individual that is ultimately responsible for the overall laboratory operation including the lab safety program and ensuring that the requirements of the CHP are followed by all staff members that work in the lab For most research and teaching laboratories the Principal Investigator PI is the Laboratory Supervisor At SCU there currently exist no programs necessitating the presence of Pls and as such the Laboratory Supervisor function is carried out by the University s Chief Lab Technician The Laboratory Supervisor may delegate some safety duties to a qualified individual but ultimately remains responsible for the safety of all personnel worki
50. es of the Laboratory Supervisor see 1 5 above Dos ABATEMENT OF DEFICIENCIES Should any University worker or CHiPs member bring deficiencies concerning lab safety to the attention of the group at large it is the primary responsibility of AOPP to address the issues and develop an appropriate action plan Should the abatement necessitate the removal or hazardous chemicals AOPP is the only department at SCU certified under OSHA s Hazardous Waste Operations and Emergency Standard HazWhoper consequently only AOPP can schedule and sign for waste removal 2 6 ANNUAL SAFETY PROGRAM AUDIT At least annually the Executive Director of AOPP and Assistant Director of AOPP perform a self audit of the CHP and full walk through of each lab associated with the University Recommendations for changes to lab practices or the CHP are made to CHiPs or if immediate action is needed the Vice President for Administration and Finance 2 7 RENEWAL OF COMMITTEE CERTIFICATION 16 Based on the findings of the audit covered in 2 6 above the Executive Director of AOPP will make a recommendation to the Vice President for Administration and Finance to renew the certification for the CHiPs Committee CHEMICAL CLASSIFICATION SYSTEMS Chemical classification systems are designed to communicate hazards The three most widely used classification systems are the OSHA Globally Harmonized System for Classifying and Labeling Chemicals recently adopted and
51. flammable liquid and 10 pounds of toxic solids Prepare a spill kit prior to transport Material such as appropriate PPE absorbent material and an empty bucket is sufficient for most small spills Carry a cell phone and know who to call 911 in the event of an emergency Transporting Chemicals on Campus via Foot Transporting small volumes of chemicals across campus via foot e g from two neighboring campus buildings is acceptable as long as it is done properly Do not attempt to move large volumes e g greater than 5 gallons in total volume of chemicals across campus via foot If a large volume of 51 chemicals needs to be moved such as an entire lab move contact AOPP for further assistance The following procedures must be followed when moving chemicals on campus by way of foot PPE must be worn when handling potentially contaminated surfaces During the time which the chemicals are moved on campus via foot PPE may not be necessary or even appropriate e g employees should not wear chemical resistant gloves in public areas However appropriate PPE and spill containment equipment should be brought along in the event of a spill or incident SCU personnel shall not dispense or sell chemicals in breakable containers of any size unless the customer has an approved transport container in which to place the chemical for transportation Approved transport container means a commercially available bottle carrier made of rubber metal or
52. g the cleanup process PPE such as gloves safety glasses and or goggles lab coat or apron chemical resistant booties Caution tape or some other means to warn people of the spill 9 4 TRAINING Effective training is crucial to a successful laboratory safety program The Laboratory Supervisor must actively participate in the training process to ensure that all lab employees are effectively trained before any work with hazardous materials occurs This chapter details the minimum training requirements for all SCU laboratories It should be noted that depending on the type of instruction being conducted and associated hazards there may be additional training requirements that are not detailed in this chapter 10 CHP TRAINING As discussed in Chapter 1 of the CHP all laboratory employees instructors graduate students lab technicians managers post docs visiting scientists etc must receive documented CHP training before any work with hazardous materials occurs The Laboratory Supervisor is responsible for providing CHP training Initial CHP training should include the following e Review the lab specific CHP in its entirety e Review lab specific hazard assessments e Review lab specific SOPs e Review any other lab specific protocol or requirements e Annual CHP Refresher Requirements After receiving the initial documented CHP training all lab employees must receive annual CHP refresher training as well This annual refresher trai
53. g the reaction for any extended period of time A number of general precautions need to be taken when working with heating devices in the laboratory When working with heating devices consider the following e The actual heating element in any laboratory heating device should be enclosed in such a fashion as to prevent a laboratory worker or any metallic conductor from accidentally touching the wire carrying the electric current e If a heating device becomes so worn or damaged that its heating element is exposed the device should be either discarded or repaired before it is used again e The external cases of all variable autotransformers have perforations for cooling by ventilation and therefore should be located where water and other chemicals cannot be spilled onto them and where they will not be exposed to flammable liquids or vapors e Fail safe devices can prevent fires or explosions that may arise if the temperature of a reaction increases significantly because of a change in line voltage the accidental loss of reaction solvent or loss of cooling Some devices will turn off the electric power if the temperature of the heating device exceeds some preset limit or if the flow of cooling water through a condenser is stopped owing to the loss of water pressure or loosening of the water supply hose to a condenser Distillation and Solvent Purification Systems The process of thermal solvent distillation is inherently dangerous If not handl
54. genic liquids will vent boil off from their storage containers as part of normal operation Containers are typically of a vacuum jacketed design to minimize heat loss Excessive venting and or an isolated ice build up on the vessel walls may indicate a fault in the vessel s integrity or a problem in the process line A leaky container should be removed from service and taken to a safe well ventilated area immediately All systems components piping valves etc must be designed to withstand extreme temperatures Pressure relief valves must be in place in systems and piping to prevent pressure buildup Any system section that could be valved off while containing cryogenic liquid must have a pressure relief valve The pressure relief valve relief ports must be positioned to face toward a safe location Transfer operations involving open cryogenic containers must be done slowly and while wearing all required PPE Care must be taken not to contact non insulated pipes and system components Open transfers will be allowed only in well ventilated areas Do not use a funnel while transferring cryogenic liquids Use tongs or other similar devices to immerse and remove objects from cryogenic liquids never immerse any part of your body into a cryogenic liquid 6 19 NANOPARTICLE SAFETY The American Society of Testing and Materials ASTM Committee on Nanotechnology has defined a nanoparticle as a particle with lengths in two or three dimensions bet
55. id Acid Base Base Oxidizer Toxic Toxic Reactive Organic inorganic organic oxidizer inorganic organic inorganic organic solvent Acid X X X X X inorganic Acid X X X X X X X organic Acid X X X X X X X oxidizer Base X X X X inorganic Base X X X X X organic Oxidizer X X X X X Toxic X X X X inorganic Toxic X X X X X organic Reactive X X X X X X X X X Organic X X X solvent 6 9 CHEMICAL STORAGE REOUIREMENTS Proper storage of chemicals is an essential component to a laboratory safety program Improper chemical storage practices can cause undesired chemical reactions which may form hazardous products that can lead to employee exposure or possibly fires and property damage All lab employees should carefully read each chemical s SDS and container label before deciding how to store a chemical as these will often indicate any special storage requirements that may be necessary The following subsections describe chemical storage requirements in more detail 6 10 GENERAL CHEMICAL STORAGE The following general chemical storage guidelines must be followed in all laboratories 37 Each chemical in the laboratory must be stored in a specific location and returned there after each use Acceptable chemical storage locations may include flammable cabinets corrosive cabinets laboratory shelves or appropriate laboratory refrigerators or freezers Chemical containers must be in good condition and a
56. ies to all personnel that work with or around hazardous chemicals or other safety and health hazards This policy is a part of the larger all encompassing SCUPPE Policy that applies to all areas not just laboratories of the regional campuses and related facilities This Laboratory PPE Policy does not cover all potential hazards e g confined space entry welding operations and high voltage in all operations or settings If a laboratory encounters hazards not covered in this Laboratory PPE Policy contact AOPP for assistance 7 1 HAZARD ASSESSMENT The hazard assessment is a process of identifying the hazards associated with a defined task and prescribing PPE along with other relevant protection measures that must be employed to minimize the risk from the hazards Hazard assessments are performed by completing a certification of hazard assessment which is a written document detailing the hazard assessment process for defined tasks The Laboratory Supervisor is responsible for ensuring that hazard assessments are performed and the certification s is written signed dated and readily available or posted in each location The Laboratory Supervisor is also responsible for ensuring that all lab personnel receive documented training on applicable hazard assessments The certification of hazard assessment should be reviewed at least annually and updated any time a process is modified or when a new task which presents a hazard is introduced into the lab
57. implemented under the OSHA Hazard Communication Standard the National Fire Protection Association NFPA system of classifying the severity of hazards and the Department of Transportation DOT hazard classes These classification systems are used by chemical manufacturers when creating safety data sheets and chemical labels therefore it is important that SCU lab employees understand the basic elements of each classification system 3 1 GLOBALLY HARMONIZED SYSTEM FOR CLASSIFYING CHEMICALS The Globally Harmonized System GHS is a world wide system adopted by OSHA for standardizing and harmonizing the classification and labeling of chemicals The objectives of the GHS are to 1 Define health physical and environmental hazards of chemicals Create classification processes that use available data on chemicals for comparison with the defined hazard criteria numerical hazard classification is based on a 1 5 scale 1 being the most hazardous and 5 being the least hazardous and 3 Communicate hazard information as well as protective measures on labels and Safety Data Sheet SDS formerly known as Material Safety Data Sheets MSDS 372 SAFETY DATA SHEETS The SDS provides comprehensive information that is imperative for the safe handling of hazardous chemicals Laboratory personnel should use the SDS as a resource to obtain information about hazards and safety precautions SDSs cannot provide information for hazards in all circumstances Howe
58. in the container while reactive materials are stored 6 13 ACUTELY TOXIC MATERIALS STORAGE Acutely toxic materials are defined as substances that may be fatal or cause damage to target organs as the result of a single exposure or exposures of short duration The following guidelines for storing acutely toxic materials must be followed in all laboratories Suitable storage locations for acutely toxic materials include desiccators glove boxes flammable storage cabinets that do not contain incompatible chemicals primarily strong acids or non domestic refrigerators or freezers These locations should be clearly posted Acutely toxic materials should be stored in secondary containment at all times as a best management practice If possible store all acutely toxic materials in a cabinet dedicated only for acutely toxic materials Signs should be posted to indicate their presence and unique hazards The amount of acutely toxic material stored in the lab should be kept at a minimum Any expired or unnecessary materials must be properly disposed of as hazardous waste All acutely toxic materials should be clearly labeled with the original manufacturer s label which should have the chemical name hazard labels and pictograms The label should not be defaced in any way 6 14 CORROSIVE MATERIALS STORAGE Corrosive materials are defined as substances that cause destruction of living tissue by chemical corrosion at the site of contact and can
59. in the laboratory To better manage and mitigate these risks SCU has developed this Chemical Hygiene Plan CHP which is intended to be the cornerstone of your laboratory safety program and is designed to aid faculty staff and students in maintaining a safe environment in which to teach and conduct research Each laboratory using hazardous materials is required to have a copy of the CHP readily available to all laboratory personnel Each laboratory worker including instructors assistants technicians etc must be familiar with the contents of the CHP and the procedures for obtaining additional safety information needed to perform their duties safely Not seeking further guidance concerning issues of safety is not an acceptable or recognized excuse 1 1 PURPOSE SCU is committed to providing a healthy and safe work environment for the campus community The SCU CHP establishes a formal written program for protecting laboratory personnel against health and safety hazards associated with exposure to hazardous chemicals and must be made available to all employees working with hazardous chemicals in a laboratory setting The CHP describes the proper use and handling procedures to be followed by faculty staff and all other personnel working with hazardous chemicals in laboratory settings 1 2 SCOPE The CHP applies to all laboratories that use store or handle hazardous chemicals and all personnel who work in these facilities The information prese
60. involve the use of chemicals should be conducted in chemical fume hoods A thorough understanding of BSC operations should be known prior to any usage 5 1 6 SAFETY SHOWERS AND EYEWASH STATIONS All laboratories using hazardous chemicals must have immediate access to safety showers and eye wash stations some of which may be portable Safety showers must have a minimum clearance of 24 inches from the centerline of the spray pattern in all directions at all times Identify the safety station with a highly visible sign and maintain an unobstructed path to it All lab personnel must be aware of the location and know how to properly use the safety shower and eyewash stations If lab personnel are exposed to a hazardous chemical they should dial 911 or someone else in the lab that is not exposed should dial 911 and use the safety shower and or eye wash unit for 15 minutes or until emergency response have personnel arrive and begin treatment If an uninjured individual is present this person should assist with the decontamination of the affected individual All eyewash stations must be flushed by laboratory personnel on a weekly basis to ensure proper working order This will keep the system free of sediment and prevent bacterial growth from reducing performance AOPP performs monthly inspections of all campus safety shower and eyewash stations This inspection evaluates the basic mechanical functionality of each station Any deficiencies are repaired b
61. ion about potential hazards and how these hazards will be mitigated SOPs must be prepared by laboratory personnel who are the most knowledgeable and involved with the experimental process However the Laboratory Supervisor is ultimately responsible for approving SOPs regardless of who prepares them The OSHA Lab Standard required SOPs to be developed for 31 all high hazard tasks that are performed in the lab High hazard tasks include any work with the following types of chemicals Explosives e Water reactive pyrophoric self heating or self reactive chemicals e Particularly hazardous substances which includes carcinogens reproductive toxins and acutely toxic substances Compressed gases e Work involving more than 1 liter of flammable liquids flammable solids corrosives oxidizers or organic peroxides at one time e High hazard tasks can also include work with equipment that creates particularly hazardous conditions Examples include solvent distillation work with high pressure systems hydrogenation work with cryogenic chemicals such as liquid nitrogen etc AOPP develops SOP templates see Appendix C that can be used by laboratories These SOPs are not complete as is they are templates that must be customized by each laboratory before they are considered complete 5 1 11 REQUIRED LABORATORY POSTINGS The following forms and labels are required to be posted in most campus laboratories e The Emergency Contact Door Posting i
62. ir Self Heating Substance A liquid or solid other than a pyrophoric substance which by reaction with air and without energy supply is liable to self heat Self Reactive Substance A liquid or solid that is liable to undergo strong exothermic thermal decomposition even without participation of oxygen air Water Reactive Substance A liquid or solid that reacts violently with water to produce a flammable or toxic gas or other hazardous conditions 4 2 HEALTH HAZARDS A chemical is a health hazard if there is statistically significant evidence based on at least one study conducted in accordance with established scientific principles that acute or chronic health effects may occur in exposed employees Each health hazard is briefly defined below Refer to Appendix B section B 2 for detailed information on each health hazard Carcinogens Substances that cause cancer Generally they are chronically toxic substances that is they cause damage after repeated or long duration exposure and their effects may only become evident after a long latency period Carcinogens are separated into two classes select carcinogens and regulated carcinogens Corrosives Substances that cause destruction of living tissue by chemical corrosion at the site of contact and can be either acidic or caustic basic 24 Hazardous Substances with Toxic Effects on Specific Organs Substances that pose adverse health effects to specific organs such as the liver
63. isposing of it Dispose of Waste e Dispose of regularly generated chemical waste within 90 days e Call EH amp S for questions e Empty Containers 77 o Dispose as hazardous waste if it once held extremely hazardous waste irrespective of the container size o Consult waste pick up schedule Safety Data Sheet SDS Location Online SDS can be accessed through SCU website Protocol Procedure Add lab specific Protocol Procedure here Click here to enter text NOTE Any deviation from this SOP requires approval from Pl Documentation of Training signature of all users is required e Prior to conducting any work with designated personnel must provide training to his her laboratory personnel specific to the hazards involved in working with this substance work area decontamination and emergency procedures e The Principal Investigator must provide his her laboratory personnel with a copy of this SOP and a copy of the SDS provided by the manufacturer e The Principal Investigator must ensure that his her laboratory personnel have attended appropriate laboratory safety training or refresher training within the last one year have read and understand the content of this SOP Name Signature Date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text Click here to enter a date Click here to enter text
64. k environment All personnel working with chemicals are responsible for staying informed on the chemicals in their work areas safe work practices and SOPs and proper personal protective equipment PPE required for the safe performance of their laboratory work General Responsibilities for Individuals When Entering Laboratory Environment As a general precaution any individuals entering a working laboratory teaching research or otherwise that use handle or store hazardous chemicals the following requirements must be met 1 Reviewing and following requirements of the CHP and all appropriate additional laboratory Safety Manuals and Policies if any 2 Following all verbal and written laboratory safety rules regulations and standard operating procedures required for the tasks assigned 3 Following the Safety Procedures for Safe use of Pyrophoric Liquid Reagents when using butyl lithium or as appropriate 4 Developing good personal chemical hygiene habits including but not limited to keeping the work areas safe and uncluttered 5 Planning reviewing and understanding the hazards of materials and processes in their laboratory research or other work procedures prior to conducting work 6 Utilizing appropriate measures to control identified hazards including consistent and proper use of engineering controls personal protective equipment and administrative controls 7 Understanding the capabilities and limitations of PPE issued to
65. k up Large gt 1 L Dial 911 Chemical Spill on Body or Clothes Remove clothing and rinse body thoroughly in emergency shower for at least 15 minutes Seek medical attention Notify supervisor immediately Chemical Splash Into Eyes Immediately rinse eyeball and inner surface of eyelid with water from the emergency eyewash station for 15 minutes by forcibly holding the eye open Seek medical attention Notify supervisor immediately e Medical Emergency Dial 911 Life Threatening Emergency After Hours Weekends And Holidays Dial 911 Note All serious injuries must be reported to EH amp S within 8 hours Needle stick puncture exposure as applicable to chemical handling procedure Wash the affected area with antiseptic soap and warm water for 15 minutes For mucous membrane exposure flush the affected area for 15 minutes using an eyewash station Report to emergency Note All needle stick ouncture exposures must be reported to EH amp S within 8 hours Decontamination Waste Disposal Procedure Click here to enter text General hazardous waste disposal guidelines Label Waste e Affixa hazardous waste tag on all waste containers using the as soon as the first drop of waste is added to the container Store Waste e Store hazardous waste in closed containers in secondary containment and in a designated location e Double bag dry waste using appropriate bags e Waste must be under the control of the person generating amp d
66. kidneys lungs etc High Acute Toxicity Substances Substances that may be fatal or cause damage to target organs as the result of a single exposure or exposures of short duration Acute toxins are quantified by a substance s lethal dose 50 LD50 or lethal concentration 50 LC50 which is the lethal dose of a compound to 50 of a laboratory tested animal population e g rats rabbits over a specified time period Irritant Substances that cause reversible inflammatory effects on living tissue by chemical action at the site of contact Reproductive Toxins Substances that may affect the reproductive capabilities including chromosomal damage mutations and effects on fetuses teratogens Sensitizer also called allergen A substance that causes exposed individuals to develop an allergic reaction in normal tissue after repeated exposure to the substance 4 3 BIOLOGICAL HAZARDS Biological hazards are hazards which involve an organism that presents a risk to humans plants animals or the environment The Laboratory Supervisor must submit to the CHiPs Committee an application to use rDNA synthetic nucleic acids potential pathogens human tissue fluids and or cell lines in their research A review is conducted in accordance with the guidance and requirements of National Institutes of Health the Centers for Disease Control and SCU policies The Laboratory Supervisory has an obligation to be closely familiar with EHS guidelines applica
67. l information for making this determination Eliminating certain chemicals as a possibility helps narrow the problem as well This is especially important for mercury PCB or dioxin compounds because they must be managed separately from other hazardous waste 8 5 3 REMOVING UNKNOWN CHEMICALS FROM THE WORK AREA If it is not possible to identify the material a Hazardous Waste label should be placed on the container as described above in Section 8 6 1 8 5 4 PREVENTING UNKNOWN CHEMICALS Here are a few tips that will help prevent the generation of unknown chemicals Label all chemical containers including beakers flasks vials and test tubes The label should be placed on the container not the cap to avoid accidental mislabeling Immediately replace labels that have fallen off or that are deteriorated Label containers using HMIS GHS Do not use abbreviations structure or formulae Archived research samples are often stored in boxes containing hundreds of small vials Label the outside of the box with the chemical constituents paying special attention to 65 regulated materials such as radioactive material organic solvents heavy metals and other toxics If the samples are nonhazardous label them as such e Request a Hazardous Materials Pickup to reduce the amount of chemicals in your laboratory e Employees should dispose of all of their waste before leaving graduating from SCU The lab and or department should come up with a syst
68. leaned and returned to storage after each use e Equipment should be stored in a safe and orderly manner that prevents it from falling e Chemical containers must be clean properly labeled and returned to storage upon completion or usage Avoid storing liquids above eye level e Do not store heavy or frequently used items on top shelves Locate items used daily close to the work area 6 5 CHEMICAL INVENTORIES It is a prudent practice to develop and maintain a chemical inventory Taking a routine chemical inventory can reduce the number of unknown chemicals and the tendency to stockpile chemicals AOPP recommends that all laboratories take a chemical inventory at least once each quarterly Depending on the type of chemicals being used and stored in a laboratory AOPP may require that a chemical inventory be prepared for a room work unit or department e g Department of Homeland Security Chemical Facility Anti Terrorism Standards Inventory on a routine basis 6 6 SAFETY DATA SHEETS 35 The SDS provides comprehensive information that is imperative for the safe handling of hazardous chemicals Carefully read the label and SDS and make sure that you understand the information provided in this document before using a chemical In some cases it may be necessary to do additional research The Laboratory Supervisor should be consulted if necessary It is important that all lab employees have access to SDS for all hazardous chemicals that are sto
69. loves must never be reused 59 Body Protection Each affected employee must wear protective clothing to protect the body from recognized hazards All unprotected skin surfaces that are at risk of injury should be covered Full length pants or full length skirt must be worn at all times by all individuals that are occupying the laboratory area shorts are not permitted Lab coats coveralls aprons or protective suits are required to be worn while working on or adjacent to all procedures using hazardous chemicals e g chemical bottle is open and the chemical is being poured transferred pipetted etc Laboratory coats must be appropriately sized for the individual and be fastened snap buttons are recommended to their full length Laboratory coat sleeves must be of a sufficient length to prevent skin exposure while wearing gloves Flame resistant laboratory coats must be worn when working with pyrophoric materials or flammable liquids greater than 1 liter in volume It is recommended that 100 cotton or other non synthetic material clothing be worn during these procedures to minimize injury in the case of a fire emergency Laboratory coats should not be worn outside of a laboratory unless the individual is traveling directly to an adjacent laboratory work area Laboratory coats should not be worn in common areas such as break rooms offices or restrooms Each department is responsible for providing laundry services as needed to maintain the h
70. lso ensure that all employees receive annual CHP refresher training The Laboratory Supervisor can provide the 12 training or delegate this task to a qualified individual e g Laboratory Safety Officer senior lab employee The CHP training must be documented See Appendix A for CHP Training Certification Form which can be used to document CHP training Failure to follow the requirements of the CHP could possibly result in injuries fines from regulatory agencies such as OSHA and or disciplinary action 1 6 LABORATORY EMPLOYEE RESPONSIBILITIES All employees e g lab technicians graduate students undergraduate students post doctoral researchers and visiting scientists in laboratories that use handle or store hazardous chemicals must Review and follow the requirements of the CHP Follow all verbal and written laboratory safety rules regulations and SOPs required for the tasks assigned 3 Develop and practice good personal chemical hygiene habits such keeping work areas clean and uncluttered 4 Plan review and understand the hazards of materials and processes in the laboratory prior to conducting work 5 Utilize appropriate measures to control hazards including consistent and proper use of engineering controls administrative controls and PPE 6 Understand the capabilities and limitations of PPE 7 Immediately report all accidents near misses and unsafe conditions to the laboratory supervisor instructor or other
71. ly hazardous substances which includes carcinogens reproductive toxins and acutely toxic substances e Compressed gases e Work involving more than 1 liter of flammable liquids flammable solids corrosives oxidizers or organic peroxides at one time e High hazard tasks can also include work with equipment that creates particularly hazardous conditions Examples include solvent distillation work with high pressure systems hydrogenation work with cryogenic chemicals such as liquid nitrogen etc The Laboratory Supervisor must ensure that all applicable personnel receive documented training on lab specific SOPs 70 Appendix A JOB DESCRIPTION AND EXPECTATIONS JOB TITLE Chief Lab Technician COLLEGE College of Science and Integrative Health STATUS Exempt REPORTS TO Dean of the college JOB SUMMARY The lab technician is a full time faculty member who reports to the Dean of the college and oversees the health professions laboratories including teaching safety compliance waste management and curriculum design JOB RESPONSIBILITIES Reporting to the Dean the Chief Lab Technician shall Support the Mission Vision and Values of SCU Ensure that the Department remains focused on educational excellence and student learning Support the Dean Improve integration across all appropriate SCU departments Collaborate with Academic Division and Department Chairs in all matters of curriculum Complete delegated tasks and respo
72. m Figure 3 2 3 illustrates the GHS label format showing the required elements 19 ACETONE PRODUCT IDENTIFIER HAZARD PICTOGRAMS Code Product Name SUPPLIER IDENTIFICATION Company Name Street Address City SIGNAL WORD Postal Code Danger Phone Number HAZARD STATEMENT Highly flammable liquid and vapor Causes mild skin irritation Causes serious eye irritation May cause drowsiness or dizziness PRECAUTIONARY STATEMENTS Keep away from heat sparks open flames hot surfaces No smoking Avoid breathing dust fumes gas mist vapors and spray IF IN EYES Rinse cautiously with water for several minutes Remove contact lenses if present and easy to do Continue rinsing Repeated exposure may cause skin dryness and cracking In Case of Fire Use water spray alcohol resistant foam dry chemical or carbon dioxide First Aid Move out of dangerous area Consult a physician If inhaled move person to fresh air If not breathing give artificial respiration In case of skin contact wash with soap and plenty of water In case of eye contact rinse thoroughly with plenty of water for at least 15 minutes If swallowed do not induce vomiting Never give anything by mouth to an unconscious person Rinse mouth with water consult a physician Figure 3 2 3 GHS Label Format As mentioned earlier one of the objectives of GHS was to create a quantitative hazard classification system numerical hazard classification i
73. n hazardous waste container All deficiencies found during the inspection should be reviewed and corrected The following elements should be performed during these inspections Housekeeping practices should be reviewed Chemicals should be stored appropriately and labeled Evidence of spills and or chemical contamination should be cleaned All glassware and equipment should be stored appropriately etc Hazard assessments should be updated if process changes have occurred For example the lab is now performing organic synthesis and working with organic metallic compounds Training records should be updated and documented if new lab personnel have not yet been trained or if any processes have changed Excess or outdated chemicals should be properly labeled and stored in the appropriate container AOPP should then be notified to schedule proper disoposal 52 Safety supplies such as PPE and spill containment equipment should be replenished if necessary Laboratory Ergonomics Many tasks in laboratories require repetitive motions which may lead to cumulative trauma injuries of the body these effects can be long term Tasks like pipetting weighing multiple samples standing at the bench or hood and using microscopes for long periods of time can cause physical stress Even time compiling data at a computer poses potential physical problems Ergonomics is the study of interaction of the human body with the work environment Ergonomics strives to
74. nd or visitors of the additional requirements PPE Training Requirements 60 Laboratory Supervisors must ensure that all employees receive PPE training before any work with hazardous materials occurs This training must be documented Each lab employee must be trained to know at least the following e When PPE is necessary e What PPE is necessary e How to properly don doff adjust and wear PPE e The limitations of the PPE and e The proper care maintenance and useful life of PPE Each affected employee must demonstrate an understanding of the training provided and the ability to use the PPE properly before performing any work requiring the use of PPE When the supervisor has reason to believe that an affected employee who has already been trained does not have the understanding and skill required e g employee is seen handling hazardous materials without wearing proper PPE then the supervisor must ensure the employee is retrained and notify the Chemical Hygiene Officer Injuries Illnesses and Medical Examinations Employees must notify the Laboratory Supervisor Department Chair or the Chemical Hygiene Officer concerning all injuries and illnesses regardless of how the magnitude The laboratory supervisor must ensure that an injury report form is completed Employees should report to a SCU approved occupational medical provider if medical attention is required this information will be provided by AOPP If the injury is
75. ng in the laboratory Additionally the Laboratory Supervisor will always serve as part of the CHiPs Committee and will be assisted by other members as requested Specifically the Laboratory Supervisor must 1 Understand applicable environmental health and safety rules including the contents of the CHP 2 Identify hazardous conditions or operations in the laboratory and establish SOPs and hazard assessments to effectively control or reduce hazards 3 Ensure that all laboratory personnel that work with hazardous chemicals receive appropriate training refer to Chapter 9 for detailed training requirements 4 Maintain written records of laboratory specific training e g PPE training 5 Ensure that appropriate PPE e g laboratory coats gloves eye protection etc and engineering control equipment e g chemical fume hood are made available in good working order and being used properly 6 Conduct periodic lab inspections and immediately take steps to abate hazards that may pose arisk to life or safety upon discovery of such hazards and 7 Actively enforce all applicable safety procedures and ensure that the CHP is followed by lab staff and all visitors including having a progressive disciplinary process for lab staff members that do not comply with safety rules The Laboratory Supervisor must ensure that employees receive CHP training and information before any work with hazardous materials occurs Laboratory Supervisors must a
76. ng is the responsibility of the Chemical Hygiene Officer 1 9 CHEMICAL HYGIENE OFFICER RESPONSIBILITIES The Chemical Hygiene Officer who is the Executive Director of Auxiliary Operations amp Physical Plant or designated individual s has the primary responsibility for ensuring the implementation of all components of the CHP The Chemical Hygiene Officer must 1 Inform the Laboratory Supervisor and Laboratory Safety Officers instructors of all health and safety requirements and assist with the selection of appropriate safety controls engineering controls administrative controls and PPE 2 Ensure that the Laboratory Supervisor has the necessary resources to maintain compliance with the CHP and that all lab staff receive appropriate training 3 Conduct periodic lab inspections and immediately take steps to abate hazards that may pose a risk to life or safety upon discovery of such hazards Ensure that SOPs and hazard assessments are being prepared 5 Maintain employee exposure monitoring records when applicable 6 Help to develop and implement appropriate environmental health and safety policies and procedures 7 Review and evaluate the effectiveness of the CHP program at least annually and update it as appropriate and 14 8 Actively enforce all applicable safety procedures and ensure the contents of the CHP are followed take appropriate actions when safety procedures are not followed 1 10 AUXILIARY OPERATIONS amp PH
77. ng system Never disable an automatic door closure device e g placing a block under the door If you are unsure of whether a door is fire rated or not contact AOPP and a staff member will come to the area to evaluate the specific door in question 5 1 9 ADMINISTRATIVE CONTROLS Administrative controls are procedural measures which can be taken to reduce or eliminate hazards associated with the use of hazardous materials Administrative controls include the following e Ensuring that employees are provided adequate documented training for safe work with hazardous materials e Careful planning of experiments and procedures with safety in mind Planning includes the development of written SOPs and hazard assessments discussed in detail in Chapter 6 for safe performance of the work e Restricting access to areas where hazardous materials are used e Using safety signs or placards to identify hazardous areas designated areas e Labeling all chemicals e Substitution of toxic materials with less toxic materials when possible e Good housekeeping and good personal hygiene such as routine hand washing and regular decontamination of areas that are possibly chemically contaminated such as bench tops and fume hoods e Prohibiting eating and drinking where chemicals are used or stored 5 1 10 STANDARD OPERATING PROCEDURESS SOPS SOPs are written instructions that detail the steps that will be performed during a given procedure and include informat
78. ning can be a condensed version of the initial CHP training but should include at least the following elements Review of the lab specific hazard assessments review of PPE requirements Review of the lab specific SOPs 69 Review of any additional lab specific rules and requirements Review of chemical spill and lab emergency procedures 10 1 PPE TRAINING As discussed in Chapter 6 of the CHP the Laboratory Supervisor must ensure that all lab employees receive documented PPE training before any work with hazardous materials occurs Document PPE training and ensure that each lab employee is trained to know at least the following When PPE is necessary What PPE is necessary How to properly don doff adjust and wear PPE The limitations of the PPE The proper care maintenance and useful life of PPE Gis fh Each affected employee must demonstrate an understanding of the training provided and the ability to use the PPE properly before performing any work requiring the use of PPE 10 2 SOP TRAINING As discussed in Chapter 4 of the CHP SOPs are written instructions that detail the steps that will be performed during a given procedure and include information about potential hazards and how these hazards will be mitigated SOPs must be developed for all high hazard tasks that are performed in the lab which is defined as work with e Explosives e Water reactive pyrophoric self heating or self reactive chemicals e Particular
79. nobstructed a minimum of 18 inches of clearance is required below the sprinkler head If the laboratory does not have fire protection sprinklers there must be a minimum of 24 inches of clearance below the ceiling e Do not store items that block fire extinguishers or eyewash and safety shower stations e Do not store items in front of electrical boxes panels in the lab e A routine cleaning schedule should be established All work surfaces should be kept as clean as possible All potentially chemically contaminated work area surfaces e g chemical fume hood deck countertops should be cleaned routinely e g daily weekly e For operations where spills and contamination are likely e g agarose gel electrophoresis ethidium bromide applications cover work spaces with a bench paper or liner The soiled bench paper should be changed on a routine basis or as needed e All chemical spills must be cleaned up immediately Refer to Chapter 8 of the CHP for detailed chemical spill cleanup procedures e Do not allow materials to accumulate in laboratory hoods and remove used tissues foil gloves or other unnecessary objects immediately after use The safety of the workspace and the hood ventilation may be compromised when excessive chemicals and equipment are kept in hoods e Ensure that all waste e g trash chemically contaminated waste etc is placed in the appropriate containers Do not overfill waste containers e All equipment should be c
80. non hazardous waste disposal instructions 8 8 LIQUID CHROMATOGRAPHY WASTE Liquid chromatography LC is an analytical technique used to separate identify quantify and purify individual components of a mixture This technique is very common in biological and chemical research Because organic solvents e g methanol acetonitrile are commonly used in the process most LC waste is regulated by the EPA as hazardous waste Consequently all containers collecting LC waste must remain closed while the LC unit is in operation It is neither acceptable to place a waste line running from the LC unit into an open waste container nor is it acceptable to use foil or Parafilm as a means of closure as shown in Figure 8 8 66 Open Waste Fail JL Parafilmo Figure 8 8 Improper LC Waste Collection Practices One of the following practices must be employed in order to comply with hazardous waste regulations for LC waste collection systems 1 Purchase an engineered container and or cap designed for LC waste collection Figure 8 9 shows several examples of acceptable solutions for proper LC waste collection that can be purchased Safety Cans Ported Cap No Threads 4 Port threaded Cap Solvent Bottle Cap Figure 8 9 Proper LC Waste Collection Options for Purchase 2 An existing cap can be modified by the research lab for LC waste collection To modify an existing cap a hole can be drilled into a cap The diameter of the hole should
81. nsibilities in a timely manner Participate in appropriate university activities serving on teams and committees including the Dean s Council as directed by the Dean Supervise as requested Proposal and implementation of department curricular improvement and development initiatives through appropriate governance structures Active participation in quality assurance processes Provide chemical safety and waste management and environmental compliance Enforce industrial hygiene Be the authority for elements of the fire safety program Take responsibility for the University s compliance with a variety of Federal state and local regulations within the laboratories Provide 24 hour availability as Incident Commander when responding to chemical spills In addition to laboratory duties the lab technician is a member of the faculty and as such is expected to engage in teaching service and scholarship Other duties and responsibilities as assigned Supervisory Responsibilities Carry out employee supervisory responsibilities in accordance with SCU s policies and applicable laws Generally these responsibilities include participation in the interviewing hiring and training of laboratory employees Further this involves planning assigning and directing work appraising performance participating in the rewarding and disciplining employees addressing complaints and resolving problems Specifically 71 o Supervise evaluate and
82. nt of Transportation DOT and or other regulatory agencies Chemicals regulated for shipping require very specific types of packaging labeling and documentation and must be prepared by trained personnel AOPP makes the determination on whether a chemical is classified as hazardous for transportation purposes Unless the researcher is DOT trained they are not authorized to make this determination Shipments that are not prepared by trained personnel can result in delays loss of research samples and potential regulatory fines AOPP is the only authorized department at SCU that may arrange for a hazardous chemical to be shipped off site Transporting Chemicals on Campus via SCU Vehicle 50 When transporting chemicals on campus all chemical containers must be properly packaged labeled and segregated according to hazard class Do not attempt to move large volumes e g greater than 5 gallons in total volume of chemicals across campus If a large volume of chemicals needs to be moved across campus such as an entire lab move contact AOPP for further assistance The following procedures must be followed in order to properly and legally transport chemicals across campus Only SCU owned vehicles are permitted to be used to transport chemicals For liability and insurance purposes no personal vehicles should ever be used to transport hazardous chemicals Ensure that each container has an appropriate tight fitting lid The lid should have the abili
83. nted in the CHP represents best practices and provides a broad overview of the information necessary for the safe operation of laboratories that utilize hazardous chemicals Laboratory use of hazardous chemicals is defined as handling or use of such chemicals in which all of the following conditions are met Chemical manipulations are carried out on a laboratory scale Multiple chemical procedures or chemicals are used 3 The procedures involved are not part of a production process nor in any way simulate a production process and 4 Protective laboratory practices and equipment are made available and in common use to minimize the potential for employee exposure to hazardous chemicals The CHP was prepared in accordance with the requirements of the Occupational Safety and Health Administration OSHA Occupational Exposure to Hazardous Chemicals in Laboratories Standard Lab Standard found in 29 CFR 1910 1450 and is based on best practices identified in among other sources the Global Harmonized System of Classification and Labeling of Chemicals Prudent 9 Practices for Handling Hazardous Chemicals in Laboratories published by the National Research Council the American Chemistry Society Task Force on Laboratory Chemical and Waste Management s Laboratory Waste Management A Guidebook the Princeton University Laboratory Safety Manual the University of California Los Angeles Chemical Hygiene Plan and the Purd
84. ombustible materials such as wood pressboard paper and organic chemicals e g organic solvents and organic acids If possible store all strong oxidizing agents in a chemical cabinet dedicated only for oxidizers The amount of oxidizers and organic peroxides stored in the lab should be kept at a minimum All material must be clearly labeled the original manufacturer s label with the chemical name hazard labels and pictograms should not be defaced or covered 6 16 REFRIGERATORS AND FREEZERS CHEMICAL STORAGE A number of general precautions need to be taken when storing chemicals in refrigerators and or freezers in the laboratory When working with freezers or refrigerators the following procedures must be followed Domestic refrigerators or freezers must never be used to store flammable liquids Flammable liquids are only allowed to be stored in refrigerators or freezers that are designed for flammable materials most refrigerators are not intended for flammable storage Lab refrigerators or freezers must never be used to store food or beverages for consumption Lab refrigerators freezers should be posted with a sign that states No Food or Drink All chemicals stored in a refrigerator or freezer must be labeled Ensure that the chemicals stored in a refrigerator or freezer is compatible with each other For example do not store an oxidizer such as hydrogen peroxide in a refrigerator with organic chemicals There must not
85. ommendations should be followed by all personnel using a glove box 28 Figure 5 3 Glove Box All personnel must receive documented training from the Pl or delegate before any work in a glove box occurs All trained personnel must understand the design features and limitations of a glove box before use The training must include detailed instruction on elements such as the ventilation and vacuum controls that maintain a pressure differential between the glove box and outside atmosphere atmospheric controls e g controlling oxygen concentrations and moisture etc Prior to use a visual glove inspection must be performed Changing of a glove must be documented date manufacturer model of glove and person performing change Gloves should not be used until they fail they should be changed according to the glove box manufacturer s recommendations or whenever necessary Plugging ports that are never or infrequently used is recommended A properly plugged port should have a stub glove and a glove port cap installed Chemical resistant gloves e g disposable nitrile gloves should be used under the glove box gloves to protect from contamination The glove box pressure must be checked every day before use and immediately after gloves are changed The pressure check must be documented Keep sharps in an approved container while in the glove box Do not work in the glove box unless the lighting is working Follow all safe work pra
86. onsibility to insert the lab specific SOPs into your customized CHP under Tab 1 located in the back of the CHP document Insert all other documented lab specific rules requirements and procedures e g equipment protocols internal lab inspections etc under Tab 2 Insert your lab specific hazard assessments under Tab 3 More details regarding hazard assessments can be found in Section 7 1 of the CHP Review update if necessary and retrain all employees on the lab specific CHP at least annually No information may be removed from any of the manuals unless in the opinion of the Lab Supervisor and the Chemical Hygiene Officer collectively any of the specific practices therein might lead to an unsafe learning working condition Such instances should be rare if they occur at all and all members of the CHiPs Committee must be notified of the change 1 4 EMPLOYEE RIGHTS AND RESPONSIBILITIES As part of the OSHA Laboratory Standard employees and other personnel who work in laboratories have the right to be informed about the potential hazards of the chemicals in their work areas and 10 to be properly trained to work safely with these substances This includes custodial and maintenance personnel support staff who work to maintain laboratories All personnel including principal investigators laboratory supervisors laboratory technicians instructors student workers and support staff have a responsibility to maintain a safe wor
87. onsidered Universal Wastes and can be legally disposed of as trash Mixed Waste hazardous waste mixed with radioactive waste EPA regulated hazardous waste should not be mistaken for biological or radiological wastes 8 1 WASTE IDENTIFICATION AND LABELING All chemical constituents in a hazardous waste container must be identified by knowledgeable laboratory personnel Not only is this required by the EPA it also ensures that waste can be properly characterized and disposed of by AOPP If there is uncertainty about the composition of a waste stream resulting from an experimental process laboratory employees must consult the laboratory supervisor for assistance In most cases careful documentation and review of all chemical products used in the experimental protocol will result in accurate waste stream characterization Additionally review SDSs specifically Section 2 Hazard Identification and Section 13 Disposal Considerations to obtain information about hazardous constituents and characteristics All waste should be properly labeled as soon the first drop of waste enters a waste container Containers must be labeled and clearly marked with words that describe the contents of the waste and the words Hazardous Waste Hazardous waste should be listed completely on the label provided by AOPP If a chemical is found in the laboratory and the composition is unknown it should be assumed to be hazardous and labeled as Hazardous Waste
88. osted tacked or hung in a visible place in every work room listed in the location s field e The fields at the beginning date s location s supervisor and signature must be completed Post signed certification in work room 79 Supervisor print Assessment Date s Signature Location s posted Task hands on work or being e Hazards within reach of potential hazards Minimum Requirements of described activity items Skin eye Volume gt 10 mL any unshielded Splash goggles chemical resistant damage corrosive liquids organic liquids or gloves lab coat skin cover to poisoning liquid mixtures or toxic inorganic knees elbows throat closed shoes inhalation of liquids mixtures with socks Work in hood Shower vapor or aerosol and eyewash must be available in work area Volume gt 1 L Same but cover to ankles wrists throat Volume gt 5L Add face shield covering chin Cataracts flash burns to cornea Work with infrared emitting equipment glass blowing Appropriate shaded goggles Lab coat closed shoe pants Conjunctivitis corneal damage erythema Arc TIG welding Appropriate shaded goggles Working gloves Skin limb injury Machine operation activities likely to catch clothing hair or jewelry Bind vulnerable clothing hair remove jewelry Eye impact Metalworking woodworking other Safety glasses operations
89. ove rotor and samples Check inside of centrifuge for possible spills and leaks clean centrifuge and rotor thoroughly if necessary Wash hands after removing gloves Stirring and Mixing Equipment 46 Stirring and mixing devices commonly found in laboratories include stirring motors magnetic stirrers and shakers These devices are typically used in lab operations that are performed in a chemical fume hood and it is important that they be operated in a way that prevents the generation of electrical sparks Only spark free induction motors should be used in power stirring and mixing devices or any other rotating equipment used for laboratory operations Because stirring and mixing devices especially stirring motors and magnetic stirrers are often operated for fairly long periods without constant attention the consequences of stirrer failure electrical overload or blockage of the motion of the stirring impeller should be considered Heating Devices Laboratories commonly use heating devices such as ovens hot plates heating mantles oil baths salt baths sand baths air baths hot tube furnaces hot air guns and microwave ovens Steam heated devices are generally preferred whenever temperatures of 100 C or less are required because they do not present shock or spark risks and can be left unattended with assurance that their temperature will never exceed 100 C Ensure the supply of water for steam generation is sufficient prior to leavin
90. plastic with carrying handle s which is large enough to hold the contents of the container if broken in transit Carrier lids or covers are recommended but not required Rubber or plastic should be used for acids alkalis and metal rubber or plastic for organic solvents Laboratory carts can be used to transport chemicals from one area to another as long as they are stable and in good condition Transport only a quantity which can be handled easily Plan the route ahead of time so as to avoid all steps or stairs Freight elevators not passenger elevators should be used to transport hazardous chemicals whenever possible The individual transporting the hazardous chemicals should operate the elevator alone if possible Avoid getting on an elevator when a person is transporting hazardous chemicals Laboratory Self Inspections AOPP performs laboratory inspections for various purposes e g routine building safety and compliance inspections However the Laboratory Supervisor a qualified designee should also inspect the laboratory for compliance with the requirements of the CHP at a minimum on a monthly basis Lab personnel have a much greater understanding of the unique hazards and issues that are encountered in their individual lab than AOPP does The goal of these inspections is to identify and correct unsafe and non compliant conditions that could potentially result in an injury to lab personnel or a fine from a regulatory agency e g ope
91. ple who must work on the vacuum lines or system and prevents vapors and related odors from being emitted back into the laboratory or system exhaust The following vacuum trapping guidelines should be followed 1 Make sure the flask is properly clamped and secured Make sure the vacuum hose is connected to the vacuum line not the gas line To prevent contamination all lines leading from experimental apparatus to the vacuum source should be equipped with filtration or other trapping device as appropriate For particulates use filtration capable of efficiently trapping the particles in the size range being generated For most aqueous or non volatile liquids a filter flask at room temperature is adequate to prevent liquids from getting to the vacuum source For solvents and other volatile liquids use a cold trap of sufficient size and cold enough to condense vapors generated followed by a filter flask capable of collecting fluid that could be aspirated out of the cold trap For highly reactive corrosive or toxic gases use a sorbent canister or scrubbing device capable of trapping the gas Research Samples and Chemicals Developed in the Lab Research samples and chemicals developed in the lab samples must be managed responsibly Samples often accumulate in labs for years and are difficult to identify and dispose of and can create unsafe and non compliant conditions if not managed properly The following requirements apply to
92. ppropriate for the chemical that they contain and be free from exterior contamination Fume hoods should not be used as permanent chemical storage areas unless designated as such Not only does this create potentially unsafe conditions by having extraneous chemicals stored near chemical reactions and processes excess chemical bottles in the hood may also seriously impair the ventilating capacity of the hood Only chemicals being used in the process or experiment being conducted in the hood are allowed to be stored in the hood and should be removed when the process or experiment is complete Chemicals should not be permanently stored on bench tops Avoid storing any chemical containers on the floor Under no circumstance should chemical containers or anything else be stored in aisle ways corridors or in front of doors Hazardous liquids should not be stored on shelves above eye level unless there is a SOP detailing safe handling procedures Chemicals should be stored at an appropriate temperature and humidity level and never be stored in direct sunlight Periodic cleanouts of expired or unneeded chemicals should be conducted to minimize the volume of hazardous chemicals stored in the laboratory Always follow the chemical manufacturer s storage instructions if provided 6 11 FLAMMABLE LIQUIDS STORAGE Flammable liquids include any liquid with a flash point no greater than 93 C 200 F The following guidelines for storing flammable liq
93. r jacket Any defective cord or cord and plug connected equipment must be removed from service and no person may use it until it is repaired and tested to ensure it is safe for use Extension cords must be of the three wire type Extension cords and flexible cords must be designed for hard or extra hard usage The rating or approval must be visible Portable equipment must be handled in a manner that will not cause damage Flexible electric cords connected to equipment may not be used for raising or lowering the equipment 53 Extension cords must be protected from damage Sharp corners and projections must be avoided Flexible cords may not be run through windows or doors unless protected from damage and then only on a temporary basis Flexible cords may not be run above ceilings or inside or through walls ceilings or floors and may not be fastened with staples or otherwise hung in such a fashion as to damage the outer jacket or insulation Extension cords used with grounding type equipment must contain an equipment grounding conductor the cord must accept a three prong or grounded plug Operating equipment with extension cords without a grounding plug is prohibited Attachment plugs and receptacles may not be connected or altered in any way that would interrupt the continuity of the equipment grounding conductor Additionally these devices may not be altered to allow the grounding pole to be inserted into current connector slots Clipping
94. rd assessment for the task to be performed 32 e Review Section 8 Exposure Controls Personal Protection of the SDS for the chemical s being used This will provide basic information on the PPE recommended for use with the particular chemical The SDS addresses worst case conditions therefore all the equipment described may not always be necessary for a specific job In addition the SDS may not provide sufficient information concerning a specific respirator or type of glove appropriate for the chemical e Additional PPE requirements are detailed in the Laboratory PPE Policy in Chapter 5 and Chapter 9 of the CHP 6 LABORATORY MANAGEMENT PLAN An effective laboratory management plan is essential to operating a safe lab environment Requirements on topics such as lab housekeeping chemical inventories proper handling storage segregation and labeling of chemicals and equipment safety must be established and known by all laboratory personnel This chapter details how laboratories should be managed at SCU 6 1 LABORATORY SAFETY GUIDELINES All laboratory employees must have a good understanding of the hazards associated with the chemicals being used and stored in the lab Basic factors such as the physical state gas liquid or solid of the chemical and the type of facilities and equipment involved with the procedure should be considered before any work with hazardous materials occurs 6 2 LABORATORY SAFETY QUESTIONS Many facto
95. rds may only be used during and for renovation maintenance repair or experimental work The following additional requirements apply Ground fault protection e g GFCI must be provided on all temporary wiring circuits including extension cords used for construction or maintenance activities 54 In general all equipment and tools connected by cord and plug must be grounded Listed or labeled double insulated tools and appliances need not be grounded Receptacles must be of the grounding type Flexible cords and cables must be of an approved type and suitable for the location and intended use They may not be used as a substitute for the fixed wiring where run through holes in walls ceilings or floors where run through doorways windows or similar openings where attached to building surfaces or where concealed behind building walls ceilings floors rugs or carpeting Suitable disconnecting switches or plug connects must be installed to permit the disconnection of all ungrounded conductors of each temporary circuit Lamps for general illumination must be protected from accidental contact or damage either by elevating the fixture above 8 feet above the floor or other working surface or by providing a suitable guard Hand lamps supplied by flexible cord must be equipped with a handle of molded composition or other approved material and must be equipped with a substantial bulb guard Flexible cords and cables must be protected from
96. red in the lab Access can mean storing hard copies of SDS in the lab or some other easily accessible location e g departmental main office or can mean storing electronically by a means that is also accessible to all lab personnel e g shared network drive To obtain a copy of a SDS contact the chemical manufacturer or AOPP Many manufacturers SDS can be found online on websites such as Siri MSDS Index The links to these resources are included below Siri MSDS Index http hazard com msds Sigma Aldrich Product Search http www sigmaaldrich com united states html 6 7 CHEMICAL LABELING REQUIREMENTS Every chemical container present in the laboratory whether hazardous or not must be properly labeled All secondary chemical containers e g wash bottles beakers flasks sample vials etc must also be properly labeled Avoid using abbreviations chemical formula or structure unless there is a complete and up to date legend e g MeOH Methanol prominently posted in the lab Most chemicals come with a manufacturer label that contains all of the necessary information so care should be taken to not damage or remove these labels It is recommended that each bottle also be dated when received and when opened to assist in determining which chemicals are expired and require proper disposal When labeling secondary chemical container utilize the HMIS or GHS system to properly identify the contents of the container 6 8 CHEMICAL SEG
97. rifugation Centrifuges must be properly installed and operated only by trained personnel Centrifuges cannot be placed in the hallway of a building they must remain inside of the laboratory Train each operator on proper operating procedures review the user manual Use only rotors compatible with the centrifuge Check the expiration date for ultracentrifuge rotors Check tubes bottles and rotors for cracks and deformities before each use Make sure that the rotor tubes and spindle are dry and clean Examine O rings and replace if worn cracked or missing Never overfill centrifuge tubes don t exceed full Always cap tubes before centrifugation Always balance buckets tubes and rotors properly Check that the rotor is seated on the drive correctly close the lid on the centrifuge and secure it When using swinging bucket rotors make sure that all buckets are hooked correctly and move freely During centrifugation Close lids at all times during operation Never open a centrifuge until the rotor has stopped Do not exceed safe rotor speed The operator should not leave the centrifuge until full operating speed is attained and the machine appears to be running safely without vibration Stop the centrifuge immediately if an unusual condition noise or vibration begins and check load balances After centrifugation Allow the centrifuge to come to a complete stop before opening Wear new pair of outer gloves to rem
98. rioration Never use a leaking corroded or damaged cylinder and never refill compressed gas cylinders When stopping a leak between cylinder and regulator always close the valve before tightening the union nut The regulator must be replaced with a safety cap when the cylinder is not in use The safety cap must be in place when a gas cylinder is moved For large gas cylinders gt 27 inches an approved gas cylinder cart should be used The cylinder must be strapped to the cart and the protective cap must be in place before moving the cylinder A cylinder should never be moved or transported without the protective cap The proper way to move a large gas cylinder is illustrated in Figure 6 7 43 Figure 6 7 Gas Cylinder Cart Never dispense from a cylinder if it is on a gas cylinder cart A few compressed gas cylinders have a shelf life and can become more hazardous as time goes on It is extremely important that these chemicals are identified and managed properly If any time sensitive gases are found to be past the manufacturer s expiration date they must be submitted to AOPP for hazardous waste disposal immediately The following is a list of time sensitive compressed gases e Hydrogen Fluoride anhydrous e Hydrogen Bromide anhydrous e Hydrogen Sulfide anhydrous e Hydrogen Cyanide anhydrous e Hydrogen Chloride anhydrous The compressed gases listed above have a shelf life provided by the manufacturer that must be s
99. rs are involved is laboratory safety Asking and answering the following questions will help address many of the factors that should be considered when it comes to laboratory safety e ls the material flammable explosive corrosive or reactive e ls the material toxic and if so how can be exposed to the material e g inhalation skin or eye contact accidental ingestion accidental puncture e What kind of ventilation do need to protect myself e What kind of PPE e g chemical resistant gloves respirator and goggles do need to protect myself e Will the process generate other toxic compounds or could it result in a fire explosion or other violent chemical reaction e What are the proper procedures for disposal of the chemicals e Dol have the proper training to handle the chemicals and carry out the process e Are my storage facilities appropriate for the type of materials will be using e Can properly segregate incompatible chemicals e What possible accidents can occur and what steps can take to minimize the likelihood and impact of an accident What is the worst incident that could result from my work 6 3 GENERAL LABORATORY SAFETY RULES 33 It is extremely important that all laboratory safety rules are known and followed by lab personnel Not only is it important that the rules are understood and followed it is also important that the Laboratory Supervisor enforce all lab safety rules A culture of safety mus
100. s excessively noisy e g operating equipment that is loud air handling unit is loud and it is difficult to communicate with co workers while in the lab contact AOPP for a noise level evaluation Respiratory Protection The use of respirators in the laboratory setting is not typically necessary since all work involving hazardous materials must be conducted in a chemical fume hood whenever possible When ventilation is not adequate to provide protection against an inhalation hazard respiratory protective equipment may be necessary There is a variety of respiratory protective equipment available for use but no one device will provide protection against all possible hazards Respirator selection is based on the chemical and process hazard and the protection factors required Respirators are not to be used except in conjunction AOPP s Respiratory Protection Program This program includes a review of the process to ensure that proper equipment is selected for the job training of all respiratory protective equipment users concerning the methods for proper use and 58 care of such equipment fitting of respirator users when required and medical surveillance of respirator users when required Respirators fitted with formaldehyde filters are assigned to each anatomy lab faculty and must be worn when entering the cold storage freezer or when scheduled to spend more than seven 7 hours inside the lab Eye and Face Protection Each affected
101. s based on a 1 5 scale 1 being the most hazardous and 5 being the least hazardous based on physical characteristics such as flash point boiling point lethal dose of 50 of a population reactivity etc Table 3 2 1 illustrates how the numerical hazard classification works for flammable liquids More detailed information on GHS can be found on the OSHA website https www osha gov dsg hazcom ghs html Category Criteria Signal Word Hazard Statement 1 Flash point lt 23 Danger Extremely C flammable liquid and vapor Boiling point lt 35 C 2 Flash point lt 23 Danger Highly C flammable liquid and vapor Boiling point gt 35 C 3 Flash point gt 23 Warning Flammable C and lt 60 C liquid and vapor 4 Flash point gt 60 Warning Combustible C and lt 93 C liquid 5 There is no Category 5 for flammable liquids Table 3 2 1 GHS Hazard Classification System for Flammable Liquids 3 4 NATIONAL FIRE PROTECTION ASSOCIATION RATING SYSTEM 20 The NFPA system uses a diamond shaped diagram of symbols and numbers to indicate the degree of hazard associated with a particular chemical This system was created to easily and quickly communicate hazards to first responders in the event of an emergency situation These diamond shaped symbols are placed on chemical containers to identify the degree of hazard associated with the specific chemical or chemical mixture The NFPA syst
102. s required for all laboratories e The Certification of Hazard Assessment Form is required for all laboratories Detailed information regarding the hazard assessment process is presented in Section 7 1 of the CHP and an example Certification of Hazard Assessment Form is located in Appendix D e The Carcinogens Reproductive Toxins or Extremely Toxic Chemicals label Toxic Chemicals Label is required if a lab uses or stores any chemicals considered by OSHA to be select carcinogens reproductive toxins and substances with a high degree of acute toxicity e An Abbreviations Acronyms and Chemical Formulas list is required for all labs that use abbreviations acronyms and or chemical formulas as a means to label chemical containers including secondary containers such as beakers flasks and vials e There are several other lab postings that may also be required that are not discussed in the CHP particularly if radioisotopes and or biological agents are used in the lab 5 1 12 PERSONAL PROTECTIVE EQUIPMENT PPE Personal protective equipment PPE should be used to supplement engineering controls However PPE should never be used as a substitute for engineering controls when engineering controls are required PPE must be worn at all time in the laboratory when handling hazardous chemicals Proper PPE selection can be determined in the following ways e Ask the Laboratory Supervisor about proper PPE selection e Review the SOP and associated haza
103. sed gas explosive organic peroxide oxidizer pyrophoric self heating 23 self reactive or water reactive Each physical hazard is briefly defined below Refer to Appendix B section B 1 for detailed information on each physical hazard Explosives A liquid or solid which is in itself capable by chemical reaction of producing gas at such a temperature and pressure and at such a speed as to cause damage to the surroundings Flammable Liquids Materials which under standard conditions can generate sufficient vapor to cause a fire in the presence of an ignition source and have a flash point no greater than 93 C 200 F Flammable Solid A solid which is readily combustible or may cause or contribute to a fire through friction Gases under Pressure Gases which are contained in a receptacle at a pressure not less than 280 kPA at 20 C or as a refrigerated liquid Organic Peroxide A liquid or solid which contains the bivalent 0 0 structure and may be considered a derivative of hydrogen peroxide where one or both of the hydrogen atoms have been replaced by organic radicals Oxidizer A liquid or solid while in itself is not necessarily combustible may generally by yielding oxygen cause or contribute to the combustion of other material Pyrophoric Substance also called Spontaneously Combustible A liquid or solid that even in small quantities and without an external ignition source can ignite after coming in contact with the a
104. serious and presents an emergency situation dial 911 and emergency responders will respond and transport the patient to a local hospital emergency room Departments must provide all employees who work with hazardous chemicals an opportunity to receive medical attention including any follow up examinations which the examining physician determines to be necessary under the following circumstances Whenever an employee develops signs or symptoms associated with a hazardous chemical to which the employee may have been exposed in the laboratory Where exposure monitoring reveals an exposure level routinely above the action level or in the absence of an action level the permissible exposure limit for an OSHA regulated substance for which there are exposure monitoring and medical surveillance requirements medical surveillance shall be established for the affected employee as prescribed by the particular standard and Whenever an event takes place in the work area such as a spill leak explosion or other occurrence resulting in the likelihood of a hazardous exposure the affected employee shall be provided an opportunity for a medical examination All medical examinations must be performed by or under the direct supervision of a licensed medical care provider and must be provided without cost to the employee 8 HAZARDOUS WASTE MANAGEMENT Introduction 61 Hazardous waste is generally defined as waste that is dangerous or potentially harmful
105. should be used Inspect glassware for any small imperfections before using Sometimes a hairline crack may be present Tap the glassware with a pen and listen to the tone to tell if there is a defect A ringing tone indicates the glassware is fine while a dull thud indicates there is a flaw present Don t keep cracked glassware If the bottom of a graduated cylinder is chipped or broken properly dispose of it Always wear appropriate PPE when working with glassware and varying temperatures Always wear safety glasses High Pressure Systems Working with high pressure systems in a laboratory can result in over pressurization explosion and the possible hazards of flying glass chemical exposure and fire All high pressure systems must be set up and operated with careful consideration of potential risks The following procedures should be followed when working with high pressure systems in the laboratory High pressure operations should be performed only in pressure vessels appropriately selected for the operation properly labeled and installed and protected by pressure relief control devices Vessels connecting hoses and any apparatus must be strong enough to withstand the stresses encountered at the intended operating temperatures and pressures and must not corrode or otherwise react when in contact with the materials it contains All pressure equipment should be visually inspected before each use Vacuum Systems Vacuum work c
106. sical Plant Department 14 Integrated Health Safety Plan IHSP ccccccccescccsssscccsssseceesssseceessececsesaececsssseceesseeeceesaececesseceesasseceesaeeeeneeaese 14 2 1 Chemical and Laboratory Safety Committee CHIPS ees see ees se ee ee ee ee ee ee RR ee ee ee Re ee ee ee ee Ge ee 14 2 2 Communication of Safety ISSUCS ee ee Ee ee ee Ge ee AA Ge Ge ee ee AG ee i Ge ee a ee Re ee ee ee ee 15 2 3 TAS A DE Ee ERG acces Ge RE ee Be GESE EE A De N Ee ee EG Ee EA Ge ee Ge ske 15 2 4 SE e TEE 15 2 5 Abatementof d ficienci s rs EE EE EES EE GERS KERE ESE ege E A BEES SEE Se Ge NEE SE Ee ee EENEG 15 2 6 Annual Safety Program Audit SEE Se Seefe ee did De AE Ee ER eg 15 2 7 Renewal of Committee CertificatiON ees ee ee ee RA AR ee GR AA ee RA AR ee Ge AR ee Ge AR Re ee ee ee ee ee be ee 15 Chemical Classification SYStERS N ee Eeer ee ee A Ve dee DE ee dues KEER eo ee ee De ER si 16 3 1 Globally Harmonized System for Classifying Chemicals iese ses se ees ee se ee Ee Re ee Ge Ge Ee ee ee ee ee Re ee ee ee ee 16 3 2 Safety Data Sheets A vaca EG A OR ee A N a Ed 16 3 3 Chemical Labeling tit AAA Ad a ERG casts ues A A Ge ge ea ee EE EE GE OER eg ee ee Ee Ee ee 17 3 4 National Fire Protection Association Rating System 20 3 5 Department of Transportation DOT Hazard Classes iii ees esse ee se ee ee ee ee Re Ge ee ee ee ee ee ee ee ee ee ee 21 Classes of Hazardous Chemicals NENNEN 22 41 Physical NN 22 AD Halt hs EK len DEE 23 4 3
107. t be adopted by all employees before a lab safety program can be successful The following general laboratory safety rules should be followed at all times Prior to beginning work in the lab be prepared for hazardous materials emergencies and know what actions to take in the event of an emergency Plan for the worst case scenario Be sure that necessary supplies and equipment are available for handling small spills of hazardous chemicals Know the location of safety equipment such as the nearest safety shower and eyewash station fire extinguisher spill kit and fire alarm pull station Do not work alone in the laboratory if you are working with high hazard materials e g acutely toxics reactive or processes that involve handling a large volume of flammable materials gt 1 liter If working with a high hazard chemical ensure that others around you know what you are working with and understand the potential hazards Limit access to areas where chemicals are used or stored by posting signs and or locking doors when areas are unattended Purchase the minimum amount of hazardous materials necessary to efficiently operate the laboratory Ensure that adequate storage facilities e g chemical storage rooms flammable safety cabinets and containers are provided for hazardous materials Ensure that hazardous materials are properly segregated by chemical compatibility Ensure that ventilation is adequate for the chemicals being used Unders
108. t daily operations involving safety and compliance 13 Empowers someone other than the Laboratory Supervisor to enforce lab safety rules 3 Provides consistency within the respective academic department idea is that each Laboratory Safety Officer attends departmental safety committee meetings and reports issues back to the lab and 4 Provides good marketable experience for the Laboratory Safety Officer to be involved in a safety leadership role The role of the Laboratory Safety Officer should include 1 Provide training to new lab personnel ensure appropriate training is given and that the training is properly documented Enforce lab safety rules 3 Attend departmental college level safety committee meetings and report significant information back to the lab and 4 Report safety issues back to the Pl when necessary 1 8 NON LABORATORY PERSONNEL SUPPORT STAFF RESPONSIBILITIES Custodians and maintenance staff support staff often must enter laboratories to perform routine tasks such as cleaning and equipment maintenance Support staff members are expected to follow the posted safety rules of each laboratory Minimum PPE requirements for support staff working in a laboratory are safety glasses long pants and closed toe shoes If additional PPE is required or if other unique safety requirements must be followed it is the lab personnes responsibility to notify support staff The procurement of support staff PPE as well as traini
109. t likely routes of exposure in the laboratory are by inhalation and or skin absorption Many hazardous chemicals may affect people through more than one of these exposure modes so it is critical that protective measures are in place for each of these exposure routes 5 1 ENGINEERING CONTROLS AND SAFETY EQUIPMENT Exposure to hazardous materials must be controlled to the greatest extent feasible by use of engineering controls Engineering controls to reduce or eliminate exposures to hazardous chemicals include e Substitution with less hazardous equipment chemicals or processes e g safety cans for glass bottles e Isolation of the operator or the process e g use of a glove box when handling air or water sensitive chemicals and e Use of forced ventilation systems e g chemical fume hood biological safety cabinet 5 1 1 CHEMICAL FUME HOODS A chemical fume hood is a type of local ventilation installation that is designed to limit exposure to hazardous or toxic fumes vapors or dusts To determine if a chemical is required to be used inside of a chemical fume hood first check the SDS for that chemical Statements found in Section 2 ona SDS such as do not breathe dust fumes or vapors or toxic by inhalation indicate the need for ventilation As a best practice always use a chemical fume hood for all work involving the handling of open chemicals e g preparing solutions whenever possible If a chemical fume hood is req
110. tain hazardous chemicals than others The SDS for the specific chemical being handled and the glove manufacturer s glove chart should be consulted to select the most appropriate glove Do not purchase gloves from a manufacturer that does not provide an adequate glove chart It is recommended that each lab purchase a general purpose disposable nitrile glove nitrile gloves are typically more versatile and provide resistance to a wider range of chemicals than latex gloves do with a minimum of a 4 mil thickness that is suitable for general chemical handling When handling chemicals with harmful temperature extremes such as liquid nitrogen or autoclaves appropriate protection such as cryogenic gloves or heat resistant gloves must be worn The volume of hazardous chemical being handled should be considered as well For example if working with a small volume of a sodium hydroxide solution disposable chemical resistant gloves provide adequate protection But if working with a large volume of sodium hydroxide as with a base bath for instance a more durable glove such as a butyl rubber should be selected to provide adequate protection Chemical resistant gloves must not be worn outside of the laboratory e g hallways elevators offices to avoid contamination of public areas Gloves should also be removed prior to handling any equipment that could likely result in cross contamination e g water fountains telephones computer work stations Disposable g
111. tand how chemical fume hoods function and be able to determine if the hood is not functioning properly Use good personal hygiene practices Keep your hands and face clean wash thoroughly with soap and water after handling any chemical Smoking drinking eating and the application of cosmetics are forbidden in areas where hazardous chemicals are in use Confine long hair and loose clothing Never smell or taste a hazardous chemical Never use mouth suction to fill a pipette When using equipment that creates potential hazards e g centrifuge ensure that the equipment is being used following the manufacturer s guidelines and instructions If equipment requires routine maintenance e g HEPA filters need to be changed ensure the maintenance is performed by a qualified individual Use required PPE as instructed by the PPE Policy detailed in Chapter 6 6 4 HOUSEKEEPING 34 Housekeeping is an important element to a laboratory safety program A clean well maintained lab improves safety by preventing accidents and can enhance the overall efficiency of the work being performed The following laboratory housekeeping guidelines should be followed e All doorways and hallways must be free of obstructions to allow clear visibility and exit The laboratory should be uncluttered without excessive storage of materials that could cause or support a fire e g paper cardboard flammable liquids etc e Fire protection sprinklers must be u
112. tely the responsibility of CHiPs to approve changes and updates to the CHP CHiPs is scheduled to meet weekly with some exceptions and is chaired by a representative from AOPP 2 2 COMMUNICATION OF SAFETY ISSUES As mentioned above CHiPs can make recommendations to the various Department Chairs Deans or other University Administrators as it deems necessary These recommendations can be informal or formal However should an issue come to the attention of the Committee that represents a significant risk to health or safety CHiPs may take a more immediate approach to communication including if necessary working with AOPP to issue an emergency alert via the University s existing Emergency Notification System In addition to suggestions CHiPs can recommend that formal infraction notices be issued by the Executive Director of AOPP for instances where lab workers have knowingly breached protocol by not following the regulations laid out in this CHP or any additional Safety Manual or training 2 3 CABINET LEVEL SPONSOR The Executive Director of Auxiliary Operations Physical Plant reports directly to the Vice President for Administration and Finance who serves as the Cabinet level supervisor for CHiPs 2 4 SELF AUDITS CHiPs reserves the right to create individual lab safety self audit checklist but will at a minimum follow the format featured in Appendix B Monthly inspections of the labs are part of the responsibiliti
113. the potential to mix with other incompatible residues in the dumpster or compactor causing a reaction or fire In addition sealed containers may become pressurized during compaction which may result 63 in residues spraying onto workers Please keep the following procedures and information in mind when disposing of empty containers e Triple rinse empty containers with a solvent capable of removing the original material e Identify triple rinsed dry odorless and empty containers by placing a Safe for Disposal on the container Contact AOPP to request a supply of these labels e Remove any cap that may cause the container to become pressurized when compacting e Arrange removal of these containers with the Building Services staff in your area or take these containers to the designated area beside the dumpster outside your building e f unable to remove residual hazardous materials from containers submit these to AOPP for pickup using the Hazardous Materials Pickup Request Form 8 4 WASTE DISPOSAL PROCEDURES AOPP provides pickup services for all chemical waste generated on campus The following procedures must be followed in order to have hazardous waste removed from campus locations 1 Prior to pick up all waste must be placed in a designated area within the room where the waste was generated 2 All waste must be placed in an appropriate container s All containers must be capped and labeled 8 5 UNKNOWN CHEMICAL WASTE
114. to human health or the environment Hazardous waste regulations are strictly enforced by both the Environmental Protection Agency EPA Department of Toxic Substance Control and the local Certified Unified Program Agency The Laboratory Supervisor and the Chemical Hygiene Officer collectively are responsible for managing the hazardous waste program in a safe and compliant manner No chemical waste should be poured down the drain or discarded in the trash unless it is certain that doing so does not violate hazardous waste regulations Hazardous wastes can be liquid solid gas or sludge They can be discarded chemicals or mixtures generated from research and teaching operations commercial products e g cleaning fluids or pesticides or by products of manufacturing processes All hazardous waste falls into one of the following categories Characteristic Wastes includes wastes that are ignitable corrosive reactive or toxic D listed Listed Wastes includes wastes from common manufacturing and industrial processes F listed wastes from specific industries K listed and wastes from commercial chemical products U and P listed Universal Waste includes certain batteries primarily rechargeable batteries such lithium nickel cadmium nickel metal hydride and mercury oxide mercury containing equipment e g thermometers thermostats and certain lamps e g fluorescent bulbs Note alkaline batteries and incandescent bulbs are not c
115. trictly followed There have been numerous incidents involving these compounds related to storage past the expiration date For example hydrogen fluoride HF and hydrogen bromide HBr cylinders have a shelf life of one to two years depending on the vendor Over time moisture can slowly enter the cylinder which initiates corrosion As the corrosion continues HF and or HBr slowly react with the internal metal walls of the cylinder to produce hydrogen The walls of the cylinder weaken due to the corrosion while at the same time the internal pressure increases due to the hydrogen generation Ultimately these cylinders fail and create extremely dangerous projectiles and a toxic gas release 6 18 CRYOGENIC LIQUIDS SAFETY A cryogenic liquid is defined as a liquid with a normal boiling point below 150 C 240 F The most common cryogenic liquid used in a laboratory setting is liquid nitrogen By definition all cryogenic liquids are extremely cold Cryogenic liquids and their vapors can rapidly freeze human tissue and can also pose an asphyxiation hazard if handled in confined spaces The following precautions should be taken when handling cryogenic liquids 44 Use and store cryogenic liquids in well ventilated areas only Wear appropriate PPE while handling cryogenic liquids Proper PPE for handling cryogenic liquids includes chemical splash goggles a face shield cryogenic safe gloves long sleeves long pants and closed toe shoes Cryo
116. ty to contain the contents of the container even if it becomes inverted during transport Examples of inappropriate lids include cracked caps loosely fitting rubber stoppers or Parafilm Chemicals should be segregated according to the primary hazard class For example do not place an oxidizer such as ammonium nitrate in the same container as an organic solvent such as acetone All containers should be packaged upright Chemical containers should be placed in some type of outer packing such as a box bin or bucket Containers should remain securely packaged during loading transport and unloading Glass to glass contact should be avoided Bubble wrap newspaper and vermiculite are good examples of packaging material that will prevent glass to glass contact The outer containers should remain tightly secured during transport Measures should be taken to avoid movement of the outer containers For example the containers should be secured using a strap or an empty box can be used to fill the gap between the last box and the sidewall of the vehicle The outer container must be labeled in a manner that identifies the contents e g corrosives flammables Transport with two or more people if possible Be prepared for unseen accidents At least one person should be knowledgeable of the materials being transported An inventory with an estimated volume or weight per hazard should be recorded and available during transport e g 5 gallons of
117. ue University Chemical Hygiene Plan It is highly recommended that all lab workers at SCU make themselves familiar with each of the above mentioned documents Certain sections covered in this CHP template are not yet applicable to the type of labs currently run by SCU i e those experiments involving the use of lasers etc however they are featured here in order to ensure this document covers all necessary laboratory safety regulations and can further be scaled to compliment more advanced laboratories as the University continues to grow 1 3 CHP USE INSTRUCTIONS The information presented in the CHP represents best practices and provides a broad overview of the information necessary for the safe operation of laboratories that utilize hazardous chemicals It is not intended to be all inclusive Departments engaged in work with hazardous chemicals or hazardous operations that are not sufficiently covered by the CHP must customize this document by adding appropriate sections in the form of standard operating procedures SOPs hazard assessments and any other written lab specific operating procedures that address the hazards and how to mitigate risks The following instructions detail how this CHP template should be used and customized by each laboratory Review this template CHP provided by AOPP Send all proposed SOPs to AOPP via campussafety SCU edu or chips SCU edu for review After review and approval it is the lab workers resp
118. uids must be followed in all laboratories Flammable and combustible liquids should be stored in flammable storage cabinets as shown in Figure 6 1 whenever possible No more than 10 gallons of flammable liquid is permitted to be stored outside of a flammable storage cabinet unless it is stored in a flammable safety can equipped with a spring loaded lid and an internal screen as shown in Figure 6 2 Domestic refrigerators or freezers must never be used to store flammable liquids Flammable liquids can only be stored in refrigerators or freezers that are designed for flammable materials most refrigerators are not intended for flammable storage Flammable liquids must be stored in well ventilated areas free from ignition sources Some organic solvents e g diethyl ether have a shelf life and can form organic peroxides over time while in storage These peroxide formers must be dated when received from the chemical manufacturer and disposed of once expired If any time sensitive chemicals are found to be past the manufacturer s expiration date AOPP must be notified for immediate hazardous waste disposal 38 Figure 6 1 Flammable Storage Cabinet Figure 6 2 Flammable Safety Can Compressed Gases Storage Compressed gases are defined as gases that are contained in a receptacle at a pressure not less than 280 kPA at 20 C or as a refrigerated liquid The following guidelines for storing compressed gases must be followed in all l
119. uired or recommended to be used the following guidelines must be followed at all times 26 Figure 5 1 Chemical Fume Hood Sash Approved Working Height Chemical fume hoods must be marked to indicate the proper sash position for optimum hood performance as illustrated in Figure 5 1 The chemical fume hood sash should be positioned at this height whenever working with hazardous chemicals that could generate toxic aerosols gases or vapors In general the sash height should be set at a level where the operator is shielded to some degree from any splashes explosions or other violent reactions which could occur and where optimum air flow dynamics are achieved Most chemical fume hoods are not intended to be used with the sash fully open The sash should only be fully opened to add or remove equipment from the chemical fume hood Chemical fume hoods must be equipped with a continuous reading monitoring device to indicate adequacy of flow All lab employees must know how to read and interpret this gauge and check that the chemical fume hood is operating properly before using hazardous chemicals in the fume hood There are different types of chemical fume hoods used at each campus so it is important that the lab employee understands the specific functions of each chemical fume hood used Only apparatus and chemicals essential to the specific procedure or process should be placed in the chemical fume hood Extraneous materials from previous experim
120. ver the SDS information enables the employer to develop an active program of worker protection measures such as training on hazard mitigation Chemical manufacturers are required to use a standard format when developing SDSs The SDS will contain 16 headings which are illustrated in Figure 3 2 1 17 Identification of the substance or e e 1 Physical and chemical properties mixture and of supplier Hazards Identification Stability and reactivity Composition information on e e 3 e 11 Toxicological information ingredients Firefighting measures Disposal considerations Regulatory information Handling and storage Exposure controls personal protection Figure 3 1 Required Sections of GHS Safety Data Sheets Other information o 6 Accidental release measures 1 Transport considerations a o 3 3 CHEMICAL LABELING The GHS standardized label elements which are not subject to variation and must appear on the chemical label contain the following elements e Symbols hazard pictograms are used to convey health physical and environmental hazard information assigned to a GHS hazard class and category e Signal Words such as Danger for more severe hazards or Warning for less severe hazards are used to emphasize hazards and indicate the relative level of severity of the hazard assigned to a GHS hazard class and category e Hazard statements e g Danger Extremely Flammable Liquid and Vapor
121. ver exceed 55 gallons per SAA e Containers should be segregated by chemical compatibility during storage e g acids away from bases secondary containment can be used as a means of segregation e Avoid halogenated and non halogenated wastes in the same waste container Avoid mixing incompatible waste streams in the same container e g acids with bases oxidizers with organic solvents that will potentially create an exothermic reaction in the waste container If mixing waste streams does create heat allow the container to vent and cool in a chemical fume hood before sealing to avoid over pressurization of the container Collect all highly toxic reactive mercury and any exotic wastes e g dioxin compounds PCBs controlled substances separately even if they are chemically compatible with other waste streams Failing to do so can result in costly disposal fees e g mixing mercury with an organic solvent waste means that the entire waste stream must be treated as mercury waste 8 3 WASTE CONTAINERS AOPP does not provide containers to campus with the exception of formaldehyde waste containers It is the responsibility of the generator of the waste to provide containers Containers unsuitable for reuse will be properly disposed of and not returned SCU s policy for the disposal of empty containers is implemented to protect SCU facilities and the Physical Plant staff when removing trash Please remember that some chemical residues have
122. ween 1 and 100 nanometers nm Nanoparticles can be composed of many different base materials and may be of different shapes including nanotubes nanowires and crystalline structures such as fullerenes and quantum dots Nanoparticles present a unique challenge from an occupational health perspective as there is a limited amount of toxicological data currently available for review However some studies have shown that existing exposure control technologies have been effective in reducing exposure to nanoparticles 6 20 SHARPS HANDLING SAFETY Sharps are defined as items capable of puncturing cutting or abrading the skin such as glass or plastic pipettes broken glass test tubes petri dishes razor blades needles and syringes with needles Sharps are often contaminated with hazardous chemicals and or infectious agents so multiple hazards are often encountered Employees that routinely work with sharps must be aware of the risk of being punctured or lacerated It is important for these employees to take precautions and properly handle sharps in order to prevent injury and potential disease transmission These 45 employees should use appropriate PPE e g puncture resistant gloves tools barrier protection sharps waste containers and engineering controls to protect themselves 6 21 EQUIPMENT APPARATUS AND INSTRUMENT SAFETY Centrifuges The following safety guidelines should be followed when operating centrifuges Before cent
123. xpired or unnecessary reactive materials must be properly disposed of as hazardous waste All reactive materials must be clearly labeled with the original manufacturer s label which should have the chemical name hazard labels and pictograms The label should not be defaced in any way All reactive materials should be placed into secondary containment as a best management practice Suitable storage locations for reactive materials include inert gas filled desiccators or glove boxes flammable storage cabinets that do not contain aqueous or other incompatible chemicals or intrinsically safe refrigerators or freezers that also do not contain aqueous or other incompatible chemicals If possible store all reactive chemicals in a small flammable cabinet dedicated only for reactive Signs should be posted to indicate their presence and unique hazards as shown in Figure 6 5 Figure 6 5 Reactive Chemicals Storage Many reactive materials are water and or air reactive and can spontaneously ignite on contact with air and or water Therefore reactive must be handled under an inert atmosphere and in such a way that rigorously excludes air and moisture If reactive materials are received in a specially designed shipping storage or dispensing container such as the Aldrich Sure Seal packaging system ensure that the integrity of that container is 40 maintained Ensure that sufficient protective solvent oil kerosene or inert gas Remains
124. y AOPP staff If the safety shower or eye wash unit becomes inoperable notify your direct supervisor and or the Lab Supervisor immediately 5 1 7 FIRE EXTINGUISHERS All fire extinguishers should be mounted on a wall in an area free of clutter Each fire extinguisher on campus is inspected on an annual basis by the Local Fire Department All laboratory personnel should be familiar with the location use and classification of the extinguishers in their laboratory Ensure that the fire extinguisher being used is appropriate for the type of material on fire before 30 attempting to extinguish any fire Laboratory personnel are not required to extinguish fires that occur in their work areas and should not attempt to do so unless 1 It is a small contained fire that can be quickly and safely extinguished e g small trash can sized fire 2 Appropriate training has been received and the individual feels the fire can be safely extinguished and 3 It is necessary to extinguish a fire in order to exit an area e g fire is blocking an exit If a fire occurs in the laboratory and is extinguished by lab personnel the local Fire Department must still be contacted immediately by dialing 911 5 1 8 FIRE DOORS Many laboratories may contain fire doors as part of the building design These doors are an important element of the fire containment system and should remain closed unless they are on a magnetic self closure or other automated self closi
125. ygiene of laboratory coats They may not be cleaned by workers at private residences or public laundry facilities Alternatives to laundering lab coats include routinely purchasing new lab coats for employees to replace contaminated lab coats or using disposable lab coats Foot Protection Closed toe shoes must be worn at all times when in the laboratory open toe shoes and or sandals are not permitted in any circumstance Each affected employee must wear protective footwear when working in areas where there is a high risk of objects falling on or rolling across the foot piercing the sole and where the feet are exposed to electrical or chemical hazards If there is a high risk of chemical contamination to the foot e g cleaning up a chemical spill on the floor then chemical resistant booties may need to worn as well Minimum PPE Requirements for Support Staff and Visitors Support staff e g custodians maintenance workers and visitors often must enter laboratories to perform routine tasks such as maintenance or take a tour of the lab These individuals are present in the laboratory but are not performing work with or directly adjacent to any work with hazardous chemicals To be present in the laboratory the minimum PPE requirements include safety glasses long pants and closed toe shoe If additional PPE is required or if other unique safety requirements must be followed it is the lab personnel s responsibility to notify support staff a

Download Pdf Manuals

Related Search

Related Contents

メーターパネル BP22  Model 9880 Intrinsically Safe Air Velocity Meter Owner`s Manual  Samsung AH68-02293B User's Manual  Impex SB 210 User's Manual  Manuel d`installation, d`utilisation et de maintenance  Massive Umbra Table lamp 43101/30/17  Samsung Встраиваемый духовой шкаф Samsung BF3N3T013 Инструкция по использованию  Sunbeam 3964-099 Iron User Manual  

Copyright © All rights reserved. Failed to retrieve file