SR-LAB™ - San Diego Instruments
Contents
1. SD Over 20 years of use in scientific research More published studies than any other startle system SR LAB startle Response The SR LAB Startle Response System the world s most widely used system for startle reflex measurement and by far the most successful for fear potentiated startle and pre pulse inhibition testing SR LAB provides a complete hardware and software solution for a wide variety of startle applications The system can be configured with up to 16 stations for testing large subject groups Intuitive yet powerful features cater to users from the educated non specialist to the sophisticated behaviorist SR LAB takes full advantage of the Windows operating system with data organization and management software that combines power and flexibility with ease of use SR LAB software controls virtually any combination of tones noise bursts lights air puffs background noise and foot shock options Flexible data organization and management software provides the ability to configure multiple test stations allowing rapid testing of a large number of subjects Importantly SR LAB supports multiple test paradigms without requiring costly add on kits or additional software SR LAB test station The SR LAB Startle Response System is the world s most widely used startle system and by far the best for testing startle habituation and pre pulse inhibition AR P N Features amp Benefits2. Acclimation Time Number of Samples to be recorded and Repetitions gt Trial List constructed using the Add Insert and Remove buttons or loading a Saved Trial List gt Inter trial Interval ITI List constructed using the Random Number Generator or manually entering time values in the list or loading a saved ITI List listed in the ITI ID list box ITI lists can be saved for reuse in other Session Definitions The Session Definition is saved for use in Test Execution ANALYSIS This is a separate module that can be installed on multiple computers to analyze and or export results All data collected by the SR LAB software is stored in a database file in table format This eliminates the need to concatenate individual files prior to export With the Analysis module simply select the session you wish to view or export There are also parameters to re score a portion of the collected data Power Flexibility Ease of Use CALIBRATION OF SR LAB TEST CABINETS SR LAB Standardization Unit the SR LAB Standardization Unit confirms the reliability of all startle animal enclosures both among enclosures and over time by transmitting a precise series of pulses to the sensor located on each enclosure Using the SR LAB Standardization Unit you can adjust each animal enclosure to the same base line value thus standardizing the responses This unit is required for any SR LAB multi station system The SR LAB software co
3. Supports all startle paradigms including startle habituation pre pulse and cross modal inhibition fear potentiated startle trace conditioning and gap detection Configure up to l6 test stations for rapid testing of large subject groups Easy to use software controls all test paradigms Plug in kits for shock puretone airpuff and light stimuli Results are reported in millivolts which is a direct read and not a derived figure such as Newtons 5 standard animal enclosures with custom styles available Analysis module to review scored data raw data and export data Designed by Scientists for Scientists The SR LAB basic components include gt Test cabinet in composite ABS gt Animal enclosure in choice of standard sizes gt Power supply gt Input and Output cables gt Software and User Manual gt Software utilities for data analysis O000080 oO 000 SR LAB Control Unit Front amp Back Other optional components and accessories can be added to the basic SR LAB system including air puff light prepulse kit high intensity light kit shocker and extra animal enclosures information please refer to the section on SR LAB Optional Components SR LAB SYSTEM CONTROL UNIT The SR LAB Control Unit consists of a computer with USB port connection chassis and software The Control Unit manages stimuli and monitors responses for up to 16 test stations simultaneously All Control Un
4. URE TONE KIT SHOCK LEVEL TESTER The Pure Tone Kit consists of a speaker for each test station and The SR LAB Shock Level Tester displays whether or not the shock audio amplifier for each four test stations Generation of the pure grid is working properly Just clip the Shock Level Tester on to a tone is done using an external program to create a wav file This Shock grid and set the appropriate shock level on the shocker The wav file is then played at the appropriate time in a trial by the shock level detected will be displayed on the LCD read out and on SR LAB software to deliver a tone Any frequency frequencies and the SR LAB Shock Level Tester You will know that the shock grid is wave form supported by the computer sound card can be used working properly when the shock level entered matches the value The supplied speaker has an upper limit of 90 KHz displayed on the LCD of the Shock Level Tester Pure Tone Kit SR LAB System Specifications ABS Isolation Cabinet 15 W x 14 D x 18 H Dimensions Control Box 16 W x 14 D x 5 H Small Animal Enclosure 3 L x 1 1 ID Small Medium Animal Enclosure 5 L x 1 ID Medium Animal Enclosure 6 L x 2 ID Large Animal Enclosure 8 L x 3 ID X Large Animal Enclosure 10 L x 5 ID Small Medium Slotted Animal Enclosure 5 L x 1 ID Large Slotted Animal Enclosure 8 L x 3 ID Weight 24 Ibs Isolat
5. ion Cabinet 3 Ibs Control Box Material Composition Isolation Cabinet ABS plastic ee Control Box Plastic Animal Enclosure Aerylie Maximum Stations 16 stations per computer Standard Cable Lengths 8 ft Certifications CE Stimuli Options Tones noise bursts background noise lights air puffs foot shocks and user defined stimuli Color Options ts White Power Flexibility Ease of Use SR LAB COMPUTER REQUIREMENTS SDI STARTLE RESPONSE TEST SYSTEMS Windows 7 compatible computer system desktop or laptop with e SR LAB available USB port Minimum disk and memory sizes specified to e SR HLAB support Windows 7 are acceptable FOR MORE INFORMATION To learn more about SDI behavioral testing systems please visit www sandiegoinstruments com If you have any questions or would like to request a quote please call 858 530 2600 or email us at sales sandiegoinstuments com SDI CONFIGURED COMPUTERS SDI offers high performance Cobalt Configured Computers that are pre installed with the Windows operating system and applicable SDI software If required SDI will pre install all relevant drivers Each computer is fully tested with your system prior to shipment When your SDI system arrives all you have to do is unpack it attach the cables and begin testing To view the online SR LAB overview presentation please visit sandiegoinstruments com presentations Specifications are subject to change without notice The equipmen
6. it operations are available from intuitive menu driven choices The Control Unit displays each animal s response on the screen and records the response on the hard disk following every trial ISOLATION CABINETS The SR LAB ABS test cabinet is uniquely designed to permit accurate results in startle reflex testing by limiting inter subject ultrasonic vocalizations and fear related pheromones Each sturdy cabinet permits full and unobtrusive observation of test animals and includes a ventilation fan light and viewing lenses In addition each cabinet contains a complete sound generation system for white noise production and accessory connections for optional stimuli Electronic circuitry is enclosed in a separate section of the cabinet The SR LAB ABS cabinets are easy to clean ANIMAL ENCLOSURES Animal enclosures are designed to locate the subject without using restraint so the animals do not suffer from restraint stress and confound the results of the startle testing The animal is free to turn around and make other movements The SR LAB enclosures are configured to focus the source of stimuli on the animal s center line assuring the level of the stimuli is consistent The SR LAB cylindrical animal enclosure monitors animal movements with a closely coupled accelerometer sensor The tubular design of the animal enclosure ensures that the animal remains centered over the sensor for consistently reliable results Other systems with a
7. ntains menu selections to help you plan execute and manage data in your startle response testing sessions s 7 The SR LAB Startle Response System from SDI has worked for us for many years both as a measure of acoustic startle and pre pulse inhibition Eastern U S Government Research Lab SR LAB Plug in Kits and Accessories A variety of optional system components can be added to your SR LAB system at any time The options include the Potentiated Shock Grid N N 4 LE Manual Shocker SR LAB Test Base Potentiated Startle Response Kit POTENTIATED STARTLE RESPONSE KIT The SR LAB Potentiated Startle Response Kit pairs foot shock with a conditioning stimulus for potentiated startle studies The conditioning stimulus can be acoustic light tactile or user supplied The shocker s display shows the actual amplitude delivered The stainless steel shock grid floor slides easily into the enclosure and is removable for cleaning The Potentiated Startle Response Kit is available for all enclosure sizes and includes gt Animal Shocker solid state constant current feedback controlled gt Shock Grid gt Cue Light gt All cables and connectors AIR PUFF KIT The Air Puff Kit is used as an alternative stimulus to the built in acoustic stimulus Each Air Puff Kit consists of solenoid control box to turn the air on and off and a delivery nozzle which mounts on the top of the animal enclosu
8. re An opening in the back of the SR LAB cabinet is used to feed the tubing to the delivery nozzle gt Solenoid Box gt Tubing gt Air Delivery Nozzle Startle Response Kit the Tactile Kit air puff stimuli the Light Kit for pre pulse stimuli the High Intensity Light Kit and the Shock Level Tester RELAY CHASSIS The SR LAB Relay Chassis makes it possible to control lights acoustic devices and other 12 VDC stimulus devices from the Dig command in the SR LAB Trial Definition application The Relay Chassis contains four solid state relays that receive communication from the Digital lines built into the control unit HIGH INTENSITY LIGHT KIT The SR LAB High Intensity Light Kit can be used to induce anxiety in test animals The light kit uses LEDs that emit 25 to 1500 lumens of light in the SR LAB cabinet The high intensity LED s do not generate heat or electrical noise that could influence an animal s reaction This kit can be connected to either the Cue Out connector on each test station or a Lights Distribution Box if the Cue Out connector is occupied by another kit LED LIGHT KIT The PPI LED Light Kit serves as an additional pre pulse stimulus It attaches to the top of the animal enclosure This kit can be connected to either the Cue Out connector on each test station or a Lights Distribution Box if the Cue Out connector is occupied by another kit Air Putt Kit Designed by Scientists for Scientists P
9. square animal enclosure permit the animal to be off center which affects the consistency of the response The enclosures are made of transparent acrylic for easy cleaning and convenient observation All enclosures are adjustable in length and come in five different sizes to accommodate adult and juvenile rats and mice Small Small Medium Medium Large and X Large Also available are slotted enclosures for tethered animals in the same sizes except Small SR LAB Animal Enclosures SR LAB software Features TEST PREPARATION TEST EXECUTION Trial Definitions you can define a trial to meet your specific Diagnostics Audio Calibration you can observe response needs Each command in a trial is selectable by checking a button channel integrity and calibrate acoustic stimulus amplitudes and entering any parameter values Choose Add Insert Edit or directly from the Oscilloscope mode reducing the preparation Delete to complete the entry of a command You can control the time needed to establish stimulus levels in startle sessions start time and the duration of each command in the trial All Trial Definitions can be saved and reused SessiD sess2 Trial 3 Channel 1 Running a Test Assign a Session ID and select the Session Session Definitions The Session Definition assembles the Definition Enter Subject information following items to provide a cohesive run definition gt Data Collection Parameters
10. t described herein is Ph 858 530 2600 designed for research and educational purposes and is not intended for the diagnosis Fax 858 530 2646 alleviation treatment monitoring or prevention of disease injury or handicap Instruments www sandiegoinstruments com San Diego Instruments Inc 2014 San Diego Instruments All rights reserved SR LAB is a trademark of San Diego 9155 Brown Deer Rd Suite 8 Instruments Inc and SDI and the SDI logo are trademarks of San Diego Instruments Inc San Diego Ch O17 All other trademarks mentioned herein are property of their respective owners
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