VivoSense ® BioRadio Import
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1. SeeFigure 2 User Documentation BioRadio Import Module Page 5 of 18 Sa BioRadio Import Configuration Wizard File Configuration Start Time 16 17 17 12 17 2010 Ev Bio Radio Channel Channel Type VivoSense Channel Downsample Hz RIP Chest Select Type None 256 0 RIP Abdomen Select Type None 256 0 ECG Select Type None 256 0 EEG Right Select Type None 256 0 EEG Left S Select Type None 256 0 EMG Select Type None 256 0 DC Aux Select Type None 256 0 Figure 2 BioRadio Import Configuration Wizard Selecting a channel type If you would like to modify the VivoSense channel name simply click on it and another drop down box will appear with alternative possibilities A VivoSense channel name can only be used once This will result in an error message after selecting the Done button if multiple BioRadio channel names have been assigned to a single VivoSense channel VivoSense will automatically down sample BioRadio channels to the minimum appropriate sampling frequency possible for the selected channel type Down sampling reduces unnecessary file size and noise in the data caused by over sampling a channel For example an accelerometer channel sampled at 256 Hz alongside an ECG channel will be automatically down sampled to 64 Hz while the ECG channel will remain sampled at the appropriate rate of 256 Hz Vivosense will down sample appropriate channels in factors of 2 A 256 Hz2. Available data channels from BioRadio devices may be divided into 2 categories Raw data channels from the device and derived channels as calculated by VivoSense The raw data channels from BioRadio are located in the Data Explorer under the Raw node They include Waveforms Measures and Information channels as described in the following sections All Raw channels are prefixed with BCR_ For complete information regarding the data in each of these channels please consult the hardware documentation for the specific BioRadio unit The core VivoSense manual contains a general description of the derived channels Only the derived channels that are particular to the BioRadio product are described here 3 1 Accelerometer Data Channels The BioRadio accelerometer measures acceleration along 2 axes denoted by BCR_AccX and BCR_AccY Lateral and Longitudinal respectively The raw data is measured in computer units cu with an arbitrary offset The conversion to physical units in the derivation of Core Channels AccX and AccY is obtained by scaling the raw data with a constant gain provided by the manufacturer and by shifting the offset by an amount specific to the individual hardware This calibration is done automatically upon import See the VivoSense core manual for additional information regarding axis definitions Raw Accelerometer Waveforms BCR Accx Acceleration measured along the X axis BCR AccY Acceleration measured along t
3. Channels 14 3 7 Galvanic Skin Response GSR Data Channels 14 3 8 Spirometer Data Channels issir irnos anaa aa a a a aee aaa raaa Zeie 14 3 9 Temperature Data Channels 15 3 10 Generic Data Channels ns niire aan EE eve a e vine ee 16 4 BioRadio LAVOUS EE 18 User Documentation sti OB Radio Import Module Page 3 of 18 1 Introduction 1 1 VivoSense for BioRadio This manual describes the use of the BioRadio import module for VivoSense software and its ability to import and analyze data collected with BioRadio 150 Cleveland Medical Devices Inc series sensor system The BioRado import module is generally included as part of the core version of VivoSense For more information about available data and capabilities of the BioRadio 150 series please refer to the Cleveland Medical BioRadio 150 series user manuals 1 2 System Requirements The BioRadio import module is an add on module to VivoSense In addition to VivoSense requirements the BioRadio import module has the following system requirements e BioRadio wireless receiver to receive data wirelessly from the BioRadio 150 series and transfer it to a PC e BioRadio accessories specific to the type of data desired e g respiration band ECG electrodes etc e BioCapture software visualizes and records real time data from the BioRadio 150 series User Documentation BioRadio Import Module Page 4 of 18 2 Importing Data Ambulatory physiological da
4. channel will be down sampled to 128 Hz gt 64 Hz gt 32 Hz and so on The down sample rate can be modified by using the drop down menu in the File Import Configuration The down sample rate can be set back to the original sample rate by selecting a down sample rate of None See Figure 3 User Documentation BioRadio Import Module Page 6 of 18 Sa BioRadio Import Configuration Wizard File Configuration Start Time 10 56 33 12 07 2010 v BioRadio Channel Channel Type VivoSense Channel RIP Chest Respiration ECH BC RIP Abdomen Respiration ECH AR ECG ECG BCR_ECG1 EEG Right EEG BCR_EEG1 EEG Left EEG BCR_EEG2 EMG EMG BCR_EMG1 DC Aux BCR_Event1 Figure 3 BioRadio Import Configuration Wizard Downsample Once you have created the desired mapping of BioRadio channels to VivoSense channels press the Done button If this is a new configuration you will be prompted to save your configuration for later use This can significantly speed up subsequent imports of files with the same configurations by allowing VivoSense to automatically perform the mapping process for you Figure 4 displays how on the second import of a file with the same channels a configuration can be loaded that automatically selects the previously saved VivoSense channels D Ga Load Import Configuration a bo User 5 Modules E kd BioRadio Import Ra Sample Session Sample Session Figure 4 Bio
5. particular respiratory band type then all measurements will be derived by summing the two signals and performing the normal sequence of calculations see Core manual If only one signal is available for either the RIP or Strain type then in some instances volumetric measurement may not be accurate due to contributions to the breathing cycle from two compartments thoracic and abdominal when only a single breathing compartment is being measured Raw Respiration Waveforms BCR RipRC This is the raw respiration waveform recorded from the BioRadio Thoracic excursions are measured in non physical computer units The tidal Volume waveform Rip Vt is derived from BCR_RipRC by summing it with BCR_RipAB if available and then scaling with a gain factor obtained from a calibration procedure performed automatically on import This calibration factor is determined by scaling the estimated average peak to trough excursions to 400 ml BCR _RipAB This is the raw respiration waveform recorded from the BioRadio Abdominal excursions are measured in non physical computer units The tidal Volume waveform Rip Vt is derived from BCR_RipAB by summing it with BCR_RipRC if available and then scaling with a gain factor obtained from a calibration procedure performed automatically on import This calibration factor is determined by scaling the estimated average peak to trough excursions to 400 ml BCR _ StrainRC This is the raw respiration waveform recorde
6. raw EEG signal 3 5 Electromyogram EMG Channels The BioRadio system allows for the connection of an up to eight EMG sensors Raw Electromyogram Waveforms BCR EMG1 This is the first raw EMG signal BCR EMG2 This is the second raw EMG signal BCR EMG3 This is the third raw EMG signal BCR EMG4 This is the fourth raw EMG signal BCR EMG5 This is the fifth raw EMG signal BCR EMG6 This is the sixth raw EMG signal User Documentation Page 13 of 18 BioRadio Import Module BCR EMG7 This is the seventh raw EMG signal BCR EMG8 This is the eighth raw EMG signal 3 6 Pulse Oximeter Data Channels The BioRadio 150 system can connect to an optional Nonin pulse oximeter that calculates oxygen saturation and pulse rate Raw Pulse Oximeter Measures BCR SpO2 This raw measurement is calculated internally on the pulse oximeter and provides an indication of percent oxygen saturation BCR _ PulseRate This raw measurement is calculated internally on the pulse oximeter and provides heart rate in beats per minute These measurements are averaged to a one second interval 3 7 Galvanic Skin Response GSR Data Channels The BioRadio system allows for the connection of an optional sensor for measuring Galvanic Skin Response GSR Raw Galvanic Skin Response Waveforms BCR _ GSR This is the raw GSR waveform recorded from the optional sensor 3 8 Spirometer Data Channels The BioRadio system allows for the
7. BCR Generic8 This is the raw waveform for generic signal 8 Generic Trends Trend Generic1 This is a computed trend of the raw generic waveform BCR_Generic1 medians from five minute windows Trend Generic2 This is a computed trend of the raw generic waveform BCR_Generic2 medians from five minute windows Trend Generic3 This is a computed trend of the raw generic waveform BCR_Generic3 medians from five minute windows Trend Generic4 This is a computed trend of the raw generic waveform BCR_Generic4 medians from five minute windows Trend Generic5 This is a computed trend of the raw generic waveform BCR_Generic5 medians from five minute windows Trend Generic6 This is a computed trend of the raw generic waveform BCR_Generic6 medians from five minute windows Trend Generic7 This is a computed trend of the raw generic waveform BCR_Generic7 medians from five minute windows Trend Generic8 This is a computed trend of the raw generic waveform BCR_Generic8 medians from five minute windows User Documentation Page 17 of 18 The default is comprised of the The default is comprised of the The default is comprised of the The default is comprised of the The default is comprised of the The default is comprised of the The default is comprised of the The default is comprised of the BioRadio Import Module 4 BioRadio Layouts VivoSense contains a collection of Layouts spec
8. Radio Import Configuration Wizard Loading a configuration User Documentation BioRadio Import Module Page 7 of 18 In addition to channel mappings the start time of the recording can also be set within the Import Configuration Wizard Click on any number within the Start Time Box to change it to the desired value The format is HH mm ss dd MM yyyy Clicking on the Start Time Box s document icon will cause a calendar to appear that allows for quick selection of the recording date This start time will be saved and applied along with the channel mappings when a configuration is used in later imports 2 2 BioCapture The BioCapture software allows configuration and data recording from a single BioRadio 150 series system A brief overview of the recording process is provided here and a more detailed explanation can be found in Cleveland Medical s BioCapture documentation To set up BioCapture for a recording first start the program and search for nearby devices Your BioRadio 150 series unit must be turned on and close by for this to work Once discovered your BioRadio can be configured to record whatever physiological signals that may be attached Users create channel configurations that include the name of the signal to be recorded as well as any scaling that should be applied before the data are saved See Figure 5 It is important to note that the names given to the data channels at this point will be read in by VivoSense at the time of
9. VIVONGETICS Vivosense User Manual BioRadio Import Module VivoSense BioRadio Import Version 2 0 Vivonoetics San Diego Office 3231 Huerfano Court San Diego CA 92117 3630 Tel 858 876 8486 Fax 248 692 0980 Email info vivonoetics com Web www vivonoetics com Cautions and disclaimer VivoSense software is not a medical diagnostic tool and is intended for research and investigational purposes only VivoSense is not intended to be or to replace medical advice or review by a physician Copyright Notice Copyright 2011 Vivonoetics All rights reserved User Documentation BioRadio Import Module Page 2 of 18 Table of Contents Tee MINTO GUC HOM EE 4 1 1 VivoSense for BioRadio 2 ic tives Deeg Kueder eee ed cen dea 4 Ee IT A 24 WANBORING Dale ee 5 24 DCM EE 5 NN Ce r 8 3 4 Processing BR RT EE 10 3 1 Accelerometer Data Channels ssesesesesssrnssrrssrnsstrsstrsstnsstnsstesstesstesstenstnnstnnstnnsnnnstnnntnnntnnnenn nnt 10 3 2 Electrocardiogram ECG Data Channels 10 3 3 Respiration Data Channels sssseseseseessenssrnssrnsstrsstnsstnsstnsstnsstessrenstesstnastnnstnnstnnstnnatentnnnntnnnnnnnnt 11 3 4 Electroencephalogram EEG Channels cccccccecceeeeeeeeeceeeeeneeceeeeesaaeeeeaaeseeeeeseaeeesaeeesaaeeeeees 12 3 5 Electromyogram EMG Channels esseseeseesirssirssrrssirssirsstrsstnssrrsstnsstnnstnastnnstnnttnnstnnntnnnenn nenn nnt 13 3 6 Pulse Oximeter Data
10. arked by Rwave1 This channel may be further used to adjust specific parameters of the QRS detection algorithm for Ecg1 RR2 This channel represents the time interval between two consecutive R waves in seconds as marked by Rwave2 This channel may be further used to adjust specific parameters of the QRS detection algorithm for Ecg1 RR RR is a duplicate of either RR1 or RR2 depending on the selection for the Source Channel property of RR and represents the time interval between two consecutive R waves in seconds All subsequent derived measures for example heart rate heart rate trends or heart rate variability calculations are derived from the primary selected RR channel A secondary Ecg signal allows the user to choose the optimum source channel based on data quality and accuracy of R wave markings 3 3 Respiration Data Channels VivoSense allows for the import of up to four respiratory signals within a single bcr file These signals can come from any combination of the following One or two Respiratory Inductive Plethysmography RIP bands User Documentation BioRadio Import Module Page 11 of 18 located on either the abdomen or ribcage of the subject and one or two Strain Gauge bands located on either the abdomen or ribcage of the subject All respiratory measurements in VivoSense are divided into two categories RIP and Strain depending on the source of the data If both abdominal and thoracic signals are available for a
11. connection of an optional spirometer sensor for measuring air flow Raw Spirometer Waveforms BCR Spirometer This is the raw waveform recorded from the spirometer VivoSense expects this to be in millivolts User Documentation BioRadio Import Module Page 14 of 18 Spirometer Waveforms Flow This is the filtered and calibrated air flow waveform which was derived from the raw BCR_Spirometer waveform by applying a gain and offset and then low pass filtering the signal The gain is from hardware specifications By default the offset is set to the mean of the data 3 9 Temperature Data Channels VivoSense allows the import of up to eight temperature waveforms from the BioRadio Raw Temperature Waveforms BCR Temp This channel provides the raw temperature waveform from an optional external temperature sensor BCR Temp2 This channel provides the raw temperature waveform from an optional external temperature sensor BCR Temp3 This channel provides the raw temperature waveform from an optional external temperature sensor BCR Temp4 This channel provides the raw temperature waveform from an optional external temperature sensor BCR Temps This channel provides the raw temperature waveform from an optional external temperature sensor BCR _ Temp6 This channel provides the raw temperature waveform from an optional external temperature sensor BCR Temp7 This channel provides the raw temperature waveform from an opti
12. d from the BioRadio Thoracic excursions are measured in non physical computer units The tidal Volume waveform Strain Vt is derived from BCR_StrainRC by summing it with BCR_StrainAB if available and then scaling with a gain factor obtained from a calibration procedure performed automatically on import This calibration factor is determined by scaling the estimated average peak to trough excursions to 400 ml BCR _ StrainAB This is the raw respiration waveform recorded from the BioRadio Abdominal excursions are measured in non physical computer units The tidal Volume waveform Strain Vt is derived from BCR_StrainAB by summing it with BCR_StrainRC if available and then scaling with a gain factor obtained from a calibration procedure performed automatically on import This calibration factor is determined by scaling the estimated average peak to trough excursions to 400 ml 3 4 Electroencephalogram EEG Channels The BioRadio system allows for the connection of an up to eight EEG sensors Raw Electroencephalogram Waveforms BCR EEG This is the first raw EEG signal User Documentation BioRadio Import Module Page 12 of 18 BCR EEG2 This is the second raw EEG signal BCR EEG3 This is the third raw EEG signal BCR EEG4 This is the fourth raw EEG signal BCR EEGS5 This is the fifth raw EEG signal BCR EEG6 This is the sixth raw EEG signal BCR EEG7 This is the seventh raw EEG signal BCR EEG8 This is the eighth
13. he Y axis 3 2 Electrocardiogram ECG Data Channels VivoSense provides the ability to import up to two ECG signals for analysis These are denoted as BCR_ecg1 and BCR_ecg2 VivoSense will process both channels and perform QRS detection on both to generate two sets of R wave markings VivoSense further provides options to select one of the ECG channels as the primary source ECG for further analysis i e derived measures such as RR and HR This selection may be performed by navigating to the Properties of the RR channel and selecting either RR1 or RR2 from the Source Channel dropdown menu If only one ECG is recorded it will not be necessary to select the source channel Raw Electrocardiogram Waveforms BCR ECG Primary ECG raw signal User Documentation BioRadio Import Module Page 10 of 18 BCR ECG2 Secondary ECG raw signal Electrocardiogram Waveforms Ecg1 Filtered BCR_ecg1 Ecg2 Filtered BCR_ecg2 Electrocardiogram Markings Rwave1 This channel identifies the peak of the R wave on the corresponding Ecg1 waveform These markings are provided as a result of the QRS detection algorithm implemented in VivoSense Rwave2 This channel identifies the peak of the R wave on the corresponding Ecg2 waveform These markings are provided as a result of the QRS detection algorithm implemented in VivoSense Electrocardiogram Measures RR1 This channel represents the time interval between two consecutive R waves in seconds as m
14. ific to the BioRadio Import module The following layouts are provided with the BioRadio Import module Actigraphy This is a set of Charts suitable for evaluating the motion or activity of a subject This layout contains channels for each calibrated accelerometer axis as well as derived posture and motion measures Breath Detection and Calibration This is a specific set of Charts designed for adjusting the breath detection settings and calibrating the Vt waveform All of the charts necessary for the examination of changes in breath detection are available This layout also provides easy access to the Breath channel for adjusting breath detection settings as well as the Insp Vol channel for performing a fixed volume calibration Changing the Breath Detection settings will result in changes in Rip respiratory measures and their corresponding trends Cardiac This is a set of Charts suitable for use when evaluating cardiac information from an electrocardiogram sensor This layout contains one filtered Ecg waveform results of QRS detection and subsequent derived R R intervals A trend of the heart rate is included along with accelerometer waveforms to be used for context interpretation and identification of artifact If necessary this layout should be used for making changes to the R wave picker settings Respiration This is a set of Charts suitable for use when evaluating rip respiration data and contains several key respiration measures and
15. import Using descriptive channel names is highly recommended as this will make the import process much easier After your BioRadio 150 series device has been configured press the record button to begin viewing and saving real time data After finishing your recording press the stop button and then save the bcr file when prompted The data file may now be imported into VivoSense as described in section 2 1 Please note that BioRadio data may be susceptible to radio loss if the subject moves out of range Dropped data will appear in VivoSense as blank spaces in the data plots VivoSense will perform calculations around these losses and all VivoSense statistics and algorithms will refer only to the available data User Documentation BioRadio Import Module Page 8 of 18 VivoSense BioRadio Import Module BioRadio Configuration Name Channels Standard View Advanced View Description Programmable Channels Enabled Channel Custom Name E CH1 ECG W CH2 CH3 CH4 CH5 CHE Bandwidth CH7 E CH8 CH8 Fixed Channels E Airflow Airflow DC KZ Sufficient bandwidth DC Aux DC Aux DC 21 7V for this configuration E 02 Sat Sp02 Sensor E Pulse Rate Sp02 Sensor V Accelerometers Body Position Figure 5 BioCapture BioRadio device configuration User Documentation BioRadio Import Module Page 9 of 18 3 Processing Data Channels
16. onal external temperature sensor BCR Temps This channel provides the raw temperature waveform from an optional external temperature sensor Temperature Waveforms Temp1 This is the calibrated temperature in degrees Celsius User Documentation BioRadio Import Module Page 15 of 18 Temp2 This is the calibrated temperature in degrees Celsius Temp3 This is the calibrated temperature in degrees Celsius Temp4 This is the calibrated temperature in degrees Celsius Temp5 This is the calibrated temperature in degrees Celsius Temp6 This is the calibrated temperature in degrees Celsius Temp7 This is the calibrated temperature in degrees Celsius Temps This is the calibrated temperature in degrees Celsius 3 10 Generic Data Channels VivoSense allows for the import of other raw data signals that may not yet be sold by Cleveland Medical or are not yet fully supported Raw Generic Waveforms BCR Generic This is the raw waveform for generic signal 1 BCR Generic2 This is the raw waveform for generic signal 2 BCR Generic3 This is the raw waveform for generic signal 3 BCR _ Generic4 This is the raw waveform for generic signal 4 BCR Generic5 This is the raw waveform for generic signal 5 User Documentation Page 16 of 18 BioRadio Import Module BCR Generic This is the raw waveform for generic signal 6 BCR Generic7 This is the raw waveform for generic signal 7
17. ta from the BioRadio system is recorded through Cleveland Medical s BioCapture software and stored as a bcr file on the PC The ber file and BioCapture are discussed in the following two sections 2 1 ber File VivoSense can import bcr files saved from BioCapture The BioRadio import option is available from the File gt Import Hardware File menu Upon selecting a bcr file VivoSense will open the file and look for all available data channels These channels will then be presented along with a mapping of channels that VivoSense can import in the Import Configuration Wizard See Figure 1 Sa BioRadio Import Configuration Wizard File Geen Start Time 16 17 17 12 17 2010 Dis Bio Radio Channel Channel Type VivoSense Channel Downsample Hz RIP Chest Ignore Select Type None 256 0 RIP Abdomen Ignore Select Type None 256 0 ECG Ignore Select Type None 256 0 EEG Right Select Type None 256 0 EEG Left Select Type None 256 0 EMG Select Type None 256 0 DC Aux Select Type None 256 0 Figure 1 BioRadio Import Configuration Wizard At this point a user can select all or a subset of the channels that they would like to analyze in VivoSense To do this find the row of the desired channel and then click once on the Channel Type entry A drop down box will appear with the possible options Upon choosing the desired type a corresponding VivoSense channel name will automatically be selected for you
18. trends The Rip Vt waveform with breath detection markings as well as the accelerometer waveforms are displayed to aid with context interpretation Sleep This is a set of Charts suitable for use when evaluating sleep data and contains respiratory waveforms and measures motion and posture data as well as oxygen saturation data User Documentation BioRadio Import Module Page 18 of 18
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