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        Thermo Scientific™ SampleSeal™ 384
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1.    1  6 1        ici 6 1   Opem COSC settee ad ee eee 6 1              6 2   7       aes 3        E E E E TO 6 3   CVE TMC use tts Owe ai a dhe ca 6 3   Chapter 7 Maintenance                         FA cee eee eee eee A AEE aU 7 1  USEF MAINTENANCE ue                 7 1   MW Dll       nae SR aa Geek aa 7 1   Cleaning and de contamination              YY FE FF FF FF Fad 7 1   RACKINGSE cos   iat        ane A CF  7 2    Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   3    Table of Contents    CAG DIAN vr A A a AA WAA NF y 1 2   GUN ar an seaman eens ea woh wee ern HEFY EA 7 3   Touchscreen User 000 dida E E ddw 7 3   Non  User Maintenance  ccdx ts FR Ddw o DD a eee a ad 4   Cutting tool replacement               YY FF FF FFF FF Fad 4   Guillotine replacement                  YF FF tenet need 7 4   Chapter 8 Troubleshooting            00c ccc sce c cence eect ence AA A A AE ARR 8 1  MESSAGES  ssc ac a ad o ae atic Gee 8 1             8 2   Chapter 9 SampleSeal Remote Control               o0ooococcccccccc 9 1  General Command            9 1   Command  Set                              a WED DO a OLE ba 9 2   O a           9 2  Rescata UN NEU FN NT 9 3   E ES A 9 3   A Ae eee he arden nate Wats oe 9 3              O DDED 9 3      CUT TOI ck tents od di    NR 9 4   Roques Esta       CANCR DN aides wee op 9 4   Chapter 10  DISPOSAL       ooo c  nica iia a la ee Pelee ca 10 1    1 4   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientif
2.   CAUTION  If the waste bin is overfilled  waste foil may not be ejected from the instrument   causing the guillotine to fail     The waste bin at the rear of the instrument has sufficient capacity for 200 racks to be processed  before emptying     Cleaning and de contamination   The outer surfaces of the SampleSeal unit can be cleaned with typical non abrasive laboratory  cleaning agents or 70  alcohol solutions  The system also tolerates decontamination regimes  based on hydrogen peroxide  e g  that offered by Bioquell Inc      CAUTION  Do not use Formaldehyde as a decontamination agent as this may cause permanent  damage to components and invalidate the SampleSeal warranty  Do not use acetone as a  Cleaning agent as damage to components  especially plastics or painted surfaces  may occur     Internal surfaces may be wiped clean using the same agents  a vacuum cleaner may be used to  remove any debris within the instrument     The system may be used with samples containing DMSO as a cryopreservative but care must be  taken to prevent contact with painted surfaces and plastic components     Thermo Scientific    SampleSeal    384 tube Heat Sealer   1    Thermo Scientific                Chapter 7   Maintenance    Rack Nest    Seal quality may be impaired if the base of the 384 tube rack does not sit directly on the base of  the rack nest  The rack nest should be regularly inspected and wiped clean or a vacuum cleaner  used to remove any debris     Sealing platen    The sealing
3.   cutter and guillotine  which are wear parts     Cutting tool replacement  The cutting tool is a wear item  Contact the service team for details if replacement is required     Guillotine replacement  The guillotine is also a wear item  Contact the service team if replacement is required     7 4   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    Troubleshooting    Messages    Notifications and error messages are displayed on the messages screen accessed by touching  the Msgs button on the main screen        Selecting an individual message by touching the message text displays further information in the  Details section of the screen     To acknowledge and clear a message  select the message and press OK  Press Back to return to  main screen        Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   1    Chapter 8   Troubleshooting    Manual Recovery    WARNING  Do not attempt to override the loading or service door safety interlocks  Failure to  comply may result in serious injury     WARNING  Do not attempt to access the interior of the device through any other openings and  do not remove panels     there are no user serviceable components inside  Failure to comply may  result in serious injury or death     WARNING  Do not attempt to access the interior of the SampleSeal unit when the sealing  platen is hot  Contact with the hot platen may result in burns     To recover failed labware from the interior of the unit     e Wai
4.  WARNING  Do not attempt to access the interior of SampleSeal when the sealing platen is hot   Contact with the hot platen may result in burns     WARNING  Do not attempt to use foil other than the specified material  Failure to comply may  result in the device being damaged and invalidate the warranty     CAUTION  The edges of the sealing foil are sharp and unless handled carefully may result in  minor cuts  Wear latex or nitrile laboratory gloves when handling foil     To load a roll of foil    e Remove the service door to disconnect power to heating pins  allowing safe access to internal  components    e Allow unit to reach a safe temperature   lt 70 C    e Remove the foil cover from the top of the instrument   e Remove the waste bin from the rear of the instrument   e From the function screen disable the guillotine   e From the function screen go to the foil screen on the user interface    e Wait until the sealing platen is at a safe temperature  as indicated at the touch screen  then  remove the service door by turning the quarter turn fasteners and lifting the panel from the  location tabs at its base  Opening the service door will trigger the safety circuit and remove air  from all actuators which will now be raised     e Load the foil roll and thread the foil through the instrument following the instructions on the  inside face of the service panel    Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   5 1                      Chapter5   Loadin
5.  platen is PTFE coated to prevent the foil sticking but may need wiping clean  periodically  when unit is cool  to ensure optimum seal quality     WARNING  Do not attempt to access the interior of the SampleSeal unit when the sealing  platen is hot  Contact with the hot platen may result in burns     CAUTION  Do not use abrasive cleaning agents or scouring pads on the sealing platen as the  non stick coating will be damaged     CAUTION  Do not spray cleaning agents directly onto the sealing platen or into other parts of  the instrument  This may result in damage to the unit     To clean the sealing platen     e Wait until the platen is at 40  C  as indicated at the touchscreen  then remove the service door  by turning the quarter turn fasteners and lifting the panel from the location tabs at its base   Opening the service door will trigger the safety circuit and remove air from all actuators which  will now be raised    e Wipe the platen with a soft wet cloth  DO NOT use abrasives  cleaning agents or scouring pads  as the non stick coating will be damaged    e For stubborn deposits a solvent may be required  acetone may be used but take extreme care  to prevent contact with painted parts    e Wipe the platen dry with a soft dry cloth and inspect for any residue  if there is none replace  the service door and reset the unit    e Reset the sealing temperature    7 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific                   Maintenance   Chapt
6. 19sf                            Thermo Scientific     SampleSeal    384 tube  Heat Sealer    Version 01  April 2014    Table of Contents    Chapter 1  011005 cs inau ud a a a iaa 1 5  Sale ma A    YAR 1 5   oale MOS air ar Soni ow tad a ack Goad Aare Ue BL 1 5   DALEY LADEIS cotos aia ed 1 5   WI a aia 1 6   Technical Support Contact Details          1 6   Ghapter2 IntrOdUCtON woes eee er eae a ij 2 1  Pesci SL LS                   cata                       eaten anna Ae                     2 1   QVEIVIGW coso ir der Gh bones A ld DWN I A Fd Gh         2 2   Chapter 3 Unpacking and    1            0  51 31       3 1  Unpacking the SampleSeal units   ee aeb brinda is aid 3 1   Installing the SampleSeal Heat Sealer       3 2   Operating Conditions  0    08 00 Fad 3 2   POWE CFE debe neta and a i ia eai eS phases dad hae 3 2   IN so mice d oe Cade MoS Geko eed FFO E avec teeta alee 3 3   Ebro 3 3                  PUIG      Chapter 4 Stat UD  cocina a a il 4 1  Sale Ne raea            4 1   Pon st A E A A A E 4 2   Sealing Partially Populated Racks       4 4   FUNCIONS                       iena         arpa O TF grada NU NHU S84 aa FFAN a         aa 4 5   Accessing the function SCTEEn        4 5   Gas          aos       ca ld       Damen 4 5  A cdc tats wean tia EN HN HY NN 4 5     6 7 onan te teh a hance 4 5   Model INMOMMAUON       oho dae acta eek oe oe e bee eae eR a eee ee 4 6   Chapter  Loading TOM saa sais cosa car aaa 5 1  Chapter6 Sealing 384 format 2D tube racks      
7. 6mm pushfit connector at the rear of the instrument  The installer must ensure  that there is a means of safely isolating the air supply  for service or in the event of an emergency     CAUTION  Oil or water in the air supply and or a supply pressure greater than 10bar  140psi   will damage the instrument and invalidate the warranty     Quality Pressure Flow       Clean  dry  oil free 5 9 to 8 3 bar  85 to 120 psi  50 slpm  1 77scfm   Purge Gas    The purge gas connection is via a 4mm pushfit connector at the rear of the instrument  The  installer must ensure that there is a means of safely isolating the purge gas supply  for service or  in the event of an emergency     WARNING  Argon and Nitrogen are odorless  colorless gases that can cause serious injury  or death by suffocation  Use only in well ventilated areas and install an oxygen monitor in an  appropriate location     WARNING  DO NOT connect flammable or reactive gases to the purge supply  Failure to comply  may result in serious injury or death     CAUTION  Oil or water in the purge gas supply and or a supply pressure greater than 10bar   140psi  will damage the instrument and invalidate the warranty     Quality Pressure       Clean  dry  inert gas or nitrogen 3 5 to 8 3 bar  50 to 120 psi  5 sipm  0 18 scfm     NOTE  Purge gas must always be connected for correct operation of SampleSeal  If inert gas is  not available  tee off the air supply line via suitable Gmm 4mm reducing connector     Thermo Scientific    Sampl
8. al    384 tube Heat Sealer   3 1          Chapter 3   Unpacking and installation    Installing the SampleSeal Heat Sealer    SampleSeal is designed for laboratory use  Dimensions are given below     85 cm  33 5 in  36 2 cm  14 3 in                             ollo    Pic    61 cm  24 in                                                                                                                                                              The instrument should be installed on a flat surface in close proximity to electricity  a compressed  air supply and a purge gas supply if gas purge is required     NOTE  Ensure that there is sufficient room behind the instrument to access the ON OFF switch   Do not cover the air vents at the rear of the machine as this may cause overheating     Operating Conditions       Operating Temperature Humidity Maximum Duty Cycle  15  C to 30  C  lt 75  RH non condensing 30 racks   hour  Power    The SampleSeal instrument requires an AC main supply  The connection is made at the switched  IEC inlet at the rear of the unit        Voltage Frequency    85 to 264V AC 47 to 63 Hz    3 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific                                                                                                                                           Unpacking and installation   Chapter 3    Air  The SampleSeal instrument requires a clean  dry  oil free compressed air supply  The air    connection is via a 
9. d not be used for any other purpose  SampleSeal can be used as a standalone device or  integrated into robotic platforms    SampleSeal 384 format Sealer       Catalog Number Description   4220 384 SampleSeal 384 format Foil Heat Sealing and Cutting Instrument  4221 025 SampleSeal 25um Easy pierce Foil   Compatible Labware   3815 Matrix 384 format 70ul Open Top 2D Barcoded tube NS             Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   2 1                Chapter 2   Introduction    Overview    Removable foil cover AOS         Waste bin    Operator push  buttons  x4     Rack loading    Service door door    Electrical panel cover    Identification  label    Services connection  point       2 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    Unpacking and installation    Unpacking the SampleSeal unit    WARNING  The weight of the SampleSeal instrument is approximately 47 6kg  105Ib   Please  ensure that the instrument is handled safely by at least two people and that appropriate lifting  methods are employed  Always lift the unit using the recessed lifting handles in the base of the  unit  Never lift this equipment by the extended carriage  Failure to follow this instruction may  cause the carriage to become detached which may result in serious injury     Check that all tables  safety cabinets  and other equipment are capable of safely supporting the  SampleSeal unit     Thermo Scientific Thermo Scientific    SampleSe
10. e return  CR  character  ASCII 13  or a line feed  LF   character  ASCII 10     e commands are case insensitive    Responses from the instrument are formatted as follows     e responses from the board start with a     lt     character  ASCII 60   e this is followed by a single character digit indicating the type of response    0 Successful end of a command    1 Successful start of a command   only generated if the command does not end immediately      2 Data from an executing command  there will be 0  many of these between the  lt 1 start  and  gt 0 end    3 Failed   command was corrupted  probably a bad checksum      4 Failed   unrecognised  Command was correctly formatted but does not correspond to a  known command or it has bad parameters      5 Failed   generic failure  then some optional  response specific  text    checksum represented by characters     xx     where xx is the hexadecimal sum of all  characters before the 5       responses are terminated with a carriage return  CR  character  ASCII 13     Command Set Definition    The following sections describe the commands used to remotely operate the instrument  and the  responses expected for each command     Stop    e stops any currently underway operation  equivalent to pressing Stop button   e command    stop     e normally no response    9 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    SampleSeal Remote Control   Chapter 9    Reset Instrument  e resets the instrument  equivalent t
11. eSeal    384 tube Heat Sealer   3 3    Thermo Scientific                                     Start up    Safety    The SampleSeal heat sealer contains moving parts and high temperature components that can  cause serious injury  The SampleSeal unit is designed to protect users from these hazards under  normal operating conditions     WARNING  Do not attempt to override the loading or service door safety interlocks  Failure to  comply may result in serious injury     Do not attempt to access the interior of the device through any other openings and  do not remove panels     there are no user serviceable components inside  Failure to  comply may result in serious injury or death     In an emergency  turn off the SampleSeal unit  The power switch is located at the back of the  instrument     Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   1          Chapter 4   Startup    Power Up    To power up the instrument  connect the electrical and compressed air supplies and turn on the  power switch at the back of the instrument  After a short delay the touchscreen will be illuminated     Reset Required  Press the reset button       Press the RESET pushbutton  The instrument will initialize and  if foil is loaded and the  compressed air supply is connected  the sealer will start to warm up        4 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    Startup   Chapter 4    When the temperature is close to set point there is a short d
12. elay to allow the temperature of the  sealing platen to stabilize        The SampleSeal heat sealer is now ready for use        Thermo Scientific    SampleSeal    384 tube Heat Sealer   3    Thermo Scientific    Chapter 4   Startup    Sealing Partially Populated Racks    CAUTION  It is important that there are no tubes present in columns that have been designated  as empty  The SampleSeal operating system assumes that racks are placed on the rack nest  with column 1 closest to the instrument  Failure to comply with these conventions will result in  a failure to process the rack and manual recovery of the labware will be required     is possible to configure the SampleSeal unit to seal racks with empty columns at each or either          end  On the main screen touch the Columns tab  The 384 way SampleSeal unit is capable of     leaving columns 1 2 and 23 24 unsealed  Remove tubes from these columns for this procedure           Touch OK  or if the selection has been changed  Save to accept the column selection     NOTE  To retain the settings after a power cycle it is necessary to seal a rack     4 4   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific                Startup   Chapter 4    Functions    The SampleSeal heat sealer has a number of functions that can be enabled disabled by the user  according to requirements     Accessing the function screen    Press Func on the main screen to access the function screen        Gas Purge    purge gas is connec
13. er 7    Cutting tool    The 384 format cutter has a life of at least 1250 racks but may need cleaning periodically before  replacement to ensure optimum seal quality     WARNING  Take extreme care when accessing the interior of the SampleSeal unit when the  sealing platen is hot  Contact with the hot platen may result in burns     CAUTION  The 384 format cutter is sharp  wear laboratory gloves and take care to avoid injury     To clean the cutter     e Remove the service door by turning the quarter turn fasteners and lifting the panel from the  location tabs at its base  Opening the service door will trigger the safety circuit and remove air  from all actuators which will now be raised     e Using a soft bristle brush remove any debris from the cutting faces  For stubborn debris an air  duster may be required  Do not use any hard or abrasive item to clean the cutting tool as this  may cause permanent damage to it     e Replace the service door and reset the unit     Touchscreen User Interface    CAUTION  Do not use fluid cleaners on the touchscreen  Failure to comply may result in the  device being damaged and invalidate the warranty     To clean the touch screen gently wipe with a microfiber lens cleaner or similar lint free cloth     Thermo Scientific    SampleSeal    384 tube Heat Sealer   3    Thermo Scientific                      Chapter 7   Maintenance    Non User Maintenance    The SampleSeal unit is designed to be maintenance free with the exception of the 384 format
14. f not avoided  may result in  injury  Failure to follow CAUTION notices may result in personal injury or damage to labware or  the instrument     Warranty  Standard warranty is  12 months or 1250 sealing cycles  as recorded by the Cycle Counter  for  the cutting tool and guillotine  both of which can be replaced in the field by a qualified technician     Enhanced preventative maintenance and service packages are available  For further details   contact Technical Support     Technical Support Contact Details       North America and ROW Technical Support Europe Technical Support    Tel   49  0  6184 906 000  email  orders labequipment de thermofisher com       Thermo Scientific       Thermo Fisher Scientific Thermo Fisher Scientific  75 Panorama Creek Drive Robert Bosch Str  1  Rochester  NY 14625 USA 63505 Langenselbold  Tel    585 586 8800 Germany    1 800 625 4327  email  technicalsupport thermofisher com       Chapter 1   Notices    1 6   Thermo Scientific    SampleSeal    384 tube Heat Sealer                   Introduction    Description    The Thermo Scientific     SampleSeal    Heat Sealer is a laboratory instrument designed for  the foil sealing of racks of 2D and non 2D barcoded storage tubes  This manual describes  the function of the 384 format version of SampleSeal only and due to a policy of continuous  improvement contents are subject to change without notice     The SampleSeal Heat Sealer is intended for research use only and for use as a sealer cutter  It  shoul
15. g foil    e Index the foil by pressing the  gt  gt  button on the foil screen  Step 12 on the foil loading  instruction label   Approximately 2 meters of foil will be unwound from the reel to ensure the  foil used to seal subsequent racks has not been handled by the operator  The foil index may be  stopped at any time by pressing the STOP button     e From the function screen enable the guillotine   e Replace the foil cover   e Replace the waste bin   e Replace the service door and reset the SampleSeal instrument  e Wait for unit to return to sealing temperature    5 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    Sealing 384 format 2D tube racks    Reset    Press the RESET button to initialize the SampleSeal unit after it has been switched on and to  return the unit to a known state after a STOP or to recover from a fault or to initialize after manual  recovery from a fault     Open Close    By default  the instrument leaves the carriage extended at the end of the cycle ready for the next  rack  The rack carriage may be retracted or extended between cycles by pressing the OPEN   CLOSE push button     Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   1    Loading Labware    WARNING  Do not place your hand inside the SampleSeal unit while loading labware     there  are hot components inside the unit     WARNING  Use only specified labware  Failure to comply may result in the device being  damaged and invalidate the war
16. ic    Notices    Safety    Before using the Thermo Scientific    SampleSeal    heat sealer  you should ensure that you are  properly trained in      gt  The correct and safe operation of the SampleSeal instrument     gt  The correct and safe maintenance procedures if you are involved in the servicing or repair of  the instrument    Safety Standards    The SampleSeal heat sealer is CE compliant  Product has been Tested according to    CAN CSA 022 2 12  UL 61010 1 2012  EN 61010 1 2010    The product was voluntarily tested according to the relevant safety requirements noted above  lt  can be marked with the certification mark above  The mark must not be altered in any way  This  product certification system operated by TUV SUD    Testing and Certification Regulations     TUV    SUD America Inc  is an OSHA recognized NRTL and a Standards Council of Canada accredited  certification body     NOTE  All references to TUV and SUD include the two dots over the    U        Safety Labels    The SampleSeal unit has a number of safety labels intended to protect the operator from injury   pay attention to these labels at all times     Thermo Scientific    SampleSeal    384 tube Heat Sealer   1 5    Thermo Scientific       A WARNING notice indicates a potentially hazardous situation which  if not avoided  could  result in serious injury or death  Failure to follow WARNING notices may result in serious injury  or death     A CAUTION notice indicates a potentially hazardous situation which  i
17. ires FTDI VCP drivers on the computer      The serial communications parameters required for remote control of the instrument are     e 115200 baud  e 8 data bits   e 1 stop bit   e no parity   e no flow control    General Command Syntax    All commands and responses are expressed in plain ASCII  Any terminal emulator program can  conveniently be used to communicate with the instrument  e g  Hyperterminal or PuTTY   For ease  of use it is likely that the user would wish to configure their terminal emulation software with the  following features enabled     e local echo enable   so you can see what you type    e send carriage return and line feed for enter  add carriage return to newline    so your typed  commands end on a new line    e add Linefeed to received carriage return   so responses from the instrument are displayed  correctly    Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   9 1    Chapter 9   SampleSeal Remote Control    All commands sent to the instrument must be formatted as follows      gt  begin with a     gt     character  ASCII 62     e a     gt     is regarded as the beginning of a command even if it occurs in the middle of another  command    e the body of the command follows the     gt     character    e commands may contain an optional checksum after the body of the command  This is  represented by characters    xx     where xx is the hexadecimal sum of all characters before  the 5         commands are terminated with a carriag
18. is returned as a textual description equivalent to what is displayed on the touch  screen panel    e the status description may contain internal delimiters represented as    I    characters  ASCII 124    gt  command     st     e response     lt 0ST  status text         9 4   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    Disposal    SampleSeal is required to comply with the European Union s Waste Electrical  amp  Electronic  Equipment  WEEE  Directive 2002 96 EC  and is marked with the following symbol     Thermo Fisher Scientific has contracted with one or more recycling or disposal companies in  the European Union  EU  and these companies will dispose of or recycle this product     Please contact Thermo Fisher Scientific at the address given in the Technical Support Contacts    section of this User Manual for further information on compliance with these Directives and the  recyclers in your country     Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   10 1    Thermo Fisher Scientific  75 Panorama Creek Drive  Rochester  NY 14625 USA    Technical Support   North America  Tel    585 586 8800  1800 625 4327  Email  technicalsupport thermofisher com    Europe    Tel   49  0  6184 906 000  Email  orders labequipment de thermofisher com    thermoscientific com    O 2014 Thermo Fisher Scientific Inc  All rights reserved  All trademarks are the property of Thermo Fisher Scientific Inc  and its subsidiaries  Specifications     
19. o pressing Reset button      command    srm     e normal response is series of messages similar to   e     lt T  o     lt 2 Reset       e     lt 0       Go    e Start a cycle  equivalent to pressing the Go button    gt  command    sgo     e normal response is series of messages similar to   e     lt T  e     lt 2 Seal and Punch       e      lt 0       Open Close  e equivalent to using the Open Close button     gt  command    soc    opens the hatch if presently closed  closes it if presently open  toggle action  like button     e command    sop    opens the hatch      command    scl    closes the hatch   e normal response is series of messages similar to   e     lt I     e     lt 2 Open       e     lt 0       Feed foil     gt  equivalent to selecting one of the    feed foil    actions on the touch screen panel   gt  command    sin    feeds small amount of foil  e command    sfd    feeds longer length of foil  e normal response is series of messages similar to   e     lt T  e     lt 2 Inch Foil       e     lt 0       Thermo Scientific    SampleSeal    384 tube Heat Sealer   9 3    Thermo Scientific    Chapter 9   SampleSeal Remote Control    Cut foil    e equivalent to selecting the    cut foil    action on the touch screen panel     command    set  e normal response is series of messages similar to    e     lt T    gt      lt 2 Cut Foil       e     lt 0       Request status  e this command allows the controlling computer to request the status of the instrument    e the status 
20. ranty     CAUTION  The SampleSeal operating system assumes that racks are placed on the rack nest  with column 1 closest to the instrument  It is important that this convention is observed when  processing partially populated racks     Check that the rack nest is free from debris  Seal quality may be impaired if the base of the 384W  tubes do not sit directly on the base of the rack nest     Place the rack to be sealed in the rack nest  The rack should be oriented so that A1 is located at  the back right corner of the rack nest  A red screw indicates the A1 position        Chapter6   Sealing 384 format 2D tube racks    6 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific                      Sealing 384 format 2D tube racks   Chapter 6    Check that the rack is level and within the raised tabs at the corners of the rack nest as shown in  the picture below        GO    The GO button initiates a sealing cycle and flashes throughout the sealing cycle     STOP    The STOP button is illuminated throughout a sealing cycle and other operations  Pressing STOP  halts the SampleSeal unit immediately  If STOP is pressed mid cycle then manual recovery of  labware may be required and the instrument must be RESET     Cycle Time    The SampleSeal unit processes a fully populated rack of 384 format tubes in approximately  100 seconds     Thermo Scientific Thermo Scientific    SampleSeal    384 tube Heat Sealer   6 3    Maintenance    User maintenance    Waste Bin  
21. t for the unit to reach a safe temperature   lt  0  C      e Remove the service door by turning the quarter turn fasteners and lifting the panel from the  location tabs at its base     e The actuators will all be raised and it should be possible to move the rack carriage by hand  when the power is off  Similarly the foil drive may also be driven by hand if necessary     e Take care not to damage components inside the SampleSeal unit during recovery and remove  any debris that may be present      gt  If the cutting tool fails to retract from the rack nest  turn off power to the instrument and  manually free the tool from the rack nest  Check that there is no debris in the holes or on the  cutting tool datum pins  If necessary  apply a small amount of silicone grease with a cotton  swab to the inside of the rack nest datum holes     e Reload the foil if required   e Replace the service door and reset the instrument   e Wait for the sealing temperature to return to the original value     e Ensure the drive roller  shown below  is free of debris        8 2   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific                   SampleSeal Remote Control    The SampleSeal heat sealer can be controlled remotely from a connected computer using simple  serial commands  The instrument is provided with a USB connector for remote control operation   USB A female   When connected to a USB port on a computer a virtual serial port will be created  on the computer  requ
22. ted to the unit  tubes are automatically purged as the rack moves into the          instrument  The gas purge can be disabled at the function screen by pressing the circular button     to the left of the text        Guillotine    Similarly the guillotine can be disabled  By default SampleSeal automatically cuts the waste foil  into thin ribbons for optimum compaction in the waste bin and easy disposal  The user may wish  to disable this function and handle the waste using an alternative method     contact Technical  Support for advice on suitable waste handling methods     Carriage Extend    By default SampleSeal extends the rack loading carriage to its full extent  see section 3 2 for  dimensions  for optimum accessibility  especially when integrated with a robotic picker     For manual operation on a laboratory bench  the user may prefer that the rack is only partially    extended to save space  This is achieved by disabling the Full extend Enable function  Manual  access is unimpaired     Thermo Scientific    SampleSeal    384 tube Heat Sealer   4 5    Thermo Scientific    Chapter 4   Startup    Model Information    The info screen is accessed from the main screen and displays build information and the number  of racks the SampleSeal has processed     Due to quality control checks during manufacture the info screen the cycle count will be greater  than zero on delivery        4 6   Thermo Scientific    SampleSeal    384 tube Heat Sealer Thermo Scientific    Loading foil   
23. terms and pricing are subject to change  Not all products are available in all countries  Please consult your local sales representative for details    hermo    SCIENTIFIC    Part of Thermo Fisher Scientific    MNSAMPLESEAL384 0414       
    
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