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        348 pH/Blood Gas/Electrolytes/ Haematocrit/Analyzer
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1.           N  Remove power  connector K       4       Remove earth  connection    106122 Rev A 10 96 11    4 ASSEMBLY DISASSEMBLY              MOTOR CONNECTOR  IN 2 POSITIONS    PL14  PL12    PL11 PL 13 PL8 PL2 PLO PL PLIO    106122 Rev A 10 96 12    4 ASSEMBLY DISASSEMBLY       4 4 To replace the gas restriction tubing  Parts required   Gas restrictor kit Cat No  105185  Power down the 348     First remove the rear cover and rear panel as described in section 4 3  The gas chassis  should now be exposed  Unscrew the gas cartridges and set aside  removing the gas  restrictor tubing with the gas cartridges in place will result in venting of the gas  cartridges   Follow the procedure for removing the manifold  section 4 18   This  gives access to the restrictor tubing at the manifold end  Slide off the tubing support  collars at both ends  Remove the tubing  Replace as necessary  When replacing the  restrictor tubing  take great care to ensure the connections are properly made  as even  a small leak will result inconsiderably shorter gas cartridge life     106122 Rev A 10 96 13    4 ASSEMBLY DISASSEMBLY       CAL SLOPE PHIGAS  SELECTOR SELECTOR    BULKHEAD  MANIFOLO  APERTURE    105185  Gas restrictor kit       106122 Rev A 10 96 14    4 ASSEMBLY DISASSEMBLY       4 5 To replace the regulator pressure switch assemblies  Parts required   Gas regulator pressure switch assembly Cat No  105170  Power down the 348     Remove the rear cover  rear panel and PSU board as described in sec
2.     and two levels of Hct control and check that the  results are in range     iv  Initiate a full 2 point calibration   12      v  Measure five replicates of a blood sample and check that the CV  is within  specification     vi  Initiate a full 2 point calibration   12      106122 Rev A 10 96 35    TROUBLESHOOTING       5 1 General    Sections 3 and 4 of the operators manual provide extensive maintenance and  troubleshooting information  The information contained in this section describes  some additional procedures which will aid in determining the resolution of problems    within the instrument     5 2 Power supply checks    Basic indications of whether the main power supplies are functioning can be derived    from the status control LEDs  refer to section 5 3      The following checks are carried out on the PSU PCB   with respect to Ov  a convenient point is TP6      Voltage Test Point   12v TP1   12v TP2   5v analogue TP3   5v analogue TP4   5v digital TP5    5 3 Status indicator check    All voltages are measured    Expected value   11 5 to  12 5   11 5 to  12 5   4 8 to  5 2   4 8 to  5 2   4 75 to  5 25    The status indicators are located behind the grille on the rear panel  From left to right   viewed from the rear  these LEDs are     LED Function   1 Microprocessor  2  12v   3  12v   4  5v analogue   5  5v analogue   6  5v digital    5 4 Electrode problems    Status  Flashing  On   On   On   On   On    If there are problems with electrodes  ie unstable readings or 
3.    Schedule 13   CPU to data ports cont   d          N C 6  N C 7  CTS 8  N C 9  Schedule 14   CPU to keypad   Keypad signal CPU  PL6   Row 1        1  2  3  4  5  6  1  Row 2  7  8  9  0  C     PF  2  N C 3  Ov digital 4  Column 1     7  5  Column 2     8  6  Column 3  1  9  7  Column 4  2  0  8  Column 5  3  C  9  Column 6  4     10  Column 7  5  PF  11  Column 8  6  12   5v digital 13  N C 14    106122 Rev A 10 96 58    PRE HEATER    PROBE INTERFACE    ARE  Ys A er     T P      PROBE    V3 CAL REAGENT GAS SELECT     Ei EN CA V5 CAL REAGENT  2  V2 VENT    V1 WASH    W        P1    m P3    SLOPE CAL  GASSES    WASTE    WASH CAL    M348 HYDRAULICS DIAGRAM    K  meh  EEE    z O  PS  SAMPLE WASTE  PUMP        D2    V6 SLOPE      A REAGENT  REAGENT  PUMP     S  Pe    WASTE       DISPLAY MODULE             ELECTRODE BLOCK ASSEMBLY                                                                                                                                                                                                    SENSOR VP s  ENER HEAD AMP PCB    j  i     I     PRINTER PORTI pL3 PL1  PORT2 AMP  MUXI PCB  ee    SAMPLE  DETECTORS  SK2 CPU PCB PL6   EE      CONTROL    vy      SK7 FROM PSU  CAL GAS  PRESSURE  PL7 BE   SWITCH  PL3      PL   3    PSU PCB PL14    GER   PL12  REAGENT  PUMP  PL11 PL13 PL8 PL2 PLO PL2 PL1O PLA ER  SWITCH  TRANSFORMER        SAMPLE OO HEATER PROBE  DETECTORS kustosi CONTROL  CAL  amp  flock  Gassetect   FR SECT GASIGAL  SAMPLE WASH  amp  GAS VENT  
4.    Vent Slope Gas   Off   Off  OfEjOn Off  On  offjoff    4Secs    17 Clear Block   2 025   Off  Off On Off On Off Off    10Secs                  106122 Rev A 10 96 48                End State                                                          7 HYDRAULICS  7 2 16 Prime Sequence   Step  Action   Pumps ls Solenoids         Sample Reagent  V1  V2 V3  V4 V5  Vp        I Prime Cal  Vent Cal Gas   7 523   7 523  Off On Off Off On Off  15Secs      2 Prime Slope  Vent Cal Gas   7 523   7 523  Off On  Off Off Off On   15Secs      3 Prime Wash  Vent Slope Gas   7 523   7 523  On On Off On Off Off  15 Secs      4 Clear Block   7 523   7 523  Off Off Off Off Off Off  6Secs    7 2 17 Deproteinise Disinfect Sequence   Step  Action   Pumps   Solenoids End State         Sample  Reagent VI  V2  V3  V4 V5  Vp        1 Aspirate Solution   2 955 Off   Off  Off  Off   Off  OfEJOfE  4 5 Secs      2 Aspirate Solution  slow    1 374 Off  Off Off  Off   Off OF OF ee td    3 Aspirate Solution  fast    3 92 Off   Off Off  Off  Off Om On 11 Secs      4or Deproteinise   Off Off  Off Off  Off  Off Om On SMins      4 Disinfect   Off Off   Off Off  Off  Off OT On 10Mins      5 Wash          Note  For step 5 see section 7 2 4  7 2 18 Condition Sequence   Step  Action   Pumps   Solenoids End State         Sample Reagent  V1  V2 V3  V4 V5  Vp        I Aspirate Solution   2 955 Off   Off  Off  Off   Off   Off  Off  4 5 Sees      2 Aspirate Solution  slow    1 374 Off  Off OH OF OR On Rs      3 Condition 
5.   NW Serial Plate  accompanying i   a   Symbol denotes  documentation    EE equipment suitable    J   for alternating  OR P       current only         Gas Cartridge  Compartment ZV C Power Connector   Voltage Selector  and Fuses  IEC Symbol  denoting Type 8  equipment  Figure 2    106122 Rev A 10 96 3    2 CONTROLS AND SERVICES       2 3 The Rear Panel   selecting voltages    Open the voltage selector cover with the screwdriver supplied        Insert the two fuses into the fuse holders and slide the fuse holders into the voltage  selector        106122 Rev A 10 96 4       2 CONTROLS AND SERVICES  2 3 The Rear Panel   selecting voltage  cont   d   Voltage selected Voltage range  100V 85V to 110V  120V 102V to 132V  220V 187V to 242V  240V 204V to 264V    Slide the voltage selector bobbin into the voltage selector so that the selected voltage  is visible when the voltage selector cover is closed     CAUTION  Do not rotate the bobbin when it is fitted in the voltage selector as this  will damage the contacts        If necessary  connect a suitable plug to the line cord  Connect the line cord to the    power connector on the rear panel     Note  Do not permanently affix the line cord to the power supply     106122 Rev A 10 96       3 INSTRUMENT DESCRIPTION   3 1 General  The 348 Blood Gas Analyzer electrolyte haematocrit Blood Gas Analyzer is available  to comply with UL CSA and IEC regulations  Several languages are also available   Consult your local Chiron agent to decide on w
6.   Off Off   Off Off  Off  Off OT On 5 Mins      4 Wash        Note  For step 4 see section 7 2 4   106122 Rev A 10 96 49    7 HYDRAULICS       7 2 19 Background Sequence        Step   Sequence   Timing   Reference     1  Vent Gas  After 5 mins inactivity   7 2 20      2   Vent Gas  After a further 5 mins   7 2 20      3   Int Wash  After a further 5 mins   7 2 21      4  Go to step 1  After a further 5 mins        Step Action   Pumps Solenoids End State       Sample  Reagent  VI  v2  v3  v4 VS  Vo           Ss ee m meu led    1  Vent Slope Gas  Off   Off  Off On Off On Off Off  1Sec                   2or   Vent Cal Gas   Off   Off  Off On Off Off Off Off  1 Sec  2 Vent Cal Gas   Off   Off  Off On Off Off Off Off  4 Secs                 Step Action   Pumps Solenoids End State         Sample  Reagent  vi  V2  V3  V4  vs  V6        T   Aspirate Wash   7 523   7 523  On  Off Off Off Off Off 1 LE or 8 secs      2 Clear Wash   7 523   Off  JOffjOftJOff OffJOfEJOfE   4Secs    3 Backflush   7 523    2 025  On  Off Off  Off Off Off  2 Secs  Wash    4   VentSlope Gas  Off   Off  OfffOn off On off off  4Secs      5 Clear Block   2 025   Off  Off On Off On Off Off  10Secs                                 106122 Rev A 10 96 50    INTERCONNECTIONS       Schedule 1   PSU to electrode block    Electrode block signal   Block heater supply   Block heater control   Pre heater supply   Pre heater control   N C   N C   Voltage reference   Pre heater temperature sense voltage  Voltage reference   B
7.   Power down the instrument   Remove the reference electrode from the electrode block     Disconnect the tube passing through the outlet sample detector from the sample pump  tube and slide it out of the sample detector     Undo the two plastic screws underneath the electrode block  and lower the lower  electrode block cover  This gives access to the sample detector retaining screw   Remove this screw  Slide the sample detector sideways and forward exposing the  electrical connector at the rear of the detector  Disconnect this and remove the sample  detector     When replacing the detector  it is easier to replace the tubing by removing the insert in  the detector and threading the tubing through this prior to replacement     106122 Rev A 10 96 31    4 ASSEMBLY DISASSEMBLY       673266  Inlet Sample Detector       105671  Pre heater       473056    Block Detector Plunger ju TR      are    473057  r        TT  lt       Biock Connecto    673309  Outlet Sample Detector    106122 Rev A 10 96 32    ASSEMBLY DISASSEMBLY       4 21    To replace the amplifier board  Parts required   Amplifier board Cat No  105171    Follow the procedure describes in section 4 3 to remove the rear cover and panel   Disconnect the probe connector to the pre heater assembly and disconnect the pre   heater to the manifold connector     Disconnect the tube coming out of the second sample detector from the sample pump  tube  Remove all electrodes from the electrode block  Follow the procedure outlined  in
8.   eg new language capability added      Status on restart     As for a warm start  see section 5 6 3  with a 2pt calibration forced and Hct slope  prompted     106122 Rev A 10 96 39    TROUBLESHOOTING       5 6 3    5 6 4    Warm Start   Conditions under which this will occur    Power interruption long enough to cause a processor reset    Status on restart    Nothing changed   Calibration   If the electrode block is still inside operating temperature limits the calibration  sequence will not be affected and after a brief display of    warming up     the Ready  screen will be displayed  If the electrode block is outside temperature limits  then two  2pt calibrations 10 minutes apart will be initiated once the system achieves operating  temperature    Ram Corruption restart   Conditions under which this will occur    Corruption RAM checksum   Status at restart    Dependent on where corruption occurred    If calibration is affected two 2pt calibrations 10 minutes apart will be initiated    If other data is corrupted  default values will be assumed    If sample data is corrupted  data recall will signal no data available    On restart  the centre of the display will have    check set up    flashing  Pressing the      key will cancel this message  It is advisable to check the options in operating set up    5  and system set up   6  if this occurs     106122 Rev A 10 96 40    6 SPARES       6 1 Ordering information    When ordering spares or accessories for the 348 please give the 
9.  15   Aspirate Cal   1 808   2 025  Off Off Off Off  On  Off  SD2 detects LE      16   Measure Off Off     Off Off Off Off Off  off  End of Measure    7 2 12 Slope pH lytes Sequence    Step  Action   Pumps   Solenoids End State        Sample  Reagent ivi  V2  v3  V4 VS  V6      1 Aspirate Air   7 523   Off  l orrfofrjorrjorrforrort      4Secs      2  Aspirate Wash  7 523   7 523  On OfflOfflOfloffloff  18ec      3   Clear Wash   7 523 off  On Off Off OFf Off Off  18ec      4   Clear Wash   7 523    2 025  Onlofrjoff offjoffjoff  28ec      5   Prime Slope   1 808   2 315  Offjofrjoff offjoffjoff  38ecs      6 l Aspirate Slope  1 808   2 315  Off Off Off Off Off On   4Secs      7   Aspirate Air   1 808   2 025  Off OffJOff Off OfEJOfE  88ecs      8   Aspirate Slope  1 808   2 315  Off Off Off Off Off  On   SD2 detects LE      9   Measure Off Off      Off  Off  Off  Off  Off  off  End of Measure    7 2 13 Gas Cal Sequence    Step Action   Pumps   Solenoids End State        Sample  Reagent ivi  V2  v3 VYA  VS V6      1   ClearBlock   7 523   Off Jorrforrjorrjorr orrfor  2Ses      2  Aspirate Wash  7 523   7 523  On Off Off Off Off Off   1Sec      3   Aspirate Air   7 523 Off   Off OfE O  EJO  EJOfEJO  EJ 18ec      4   Clear Wash   7 523    2 025  On  Off OffJOff OfEJOfE  28ecs      5   Clear Cal 7 523    2 025  Off Off Off Off On  Off   7Secs      6   Vent Cal Gas   Off Off  Off On Off OfflOfIOff  10Secs      7   Aspirate Gas   2 749 Off     Off Off  On  OfflOff Off  End of Measu
10.  SLOPE  PUMP SOLENOIDS SOLENOIDS SOLENOIDS          MAINS  INLET    M348 ELECTRONICS SYSTEM   30 01 96          PEEK TUBING RESTRICTOR                      FILTER C        4 REGULATOR                   GAS 1   CAL     FILTER                      PEEK TUBING RESTRICTOR                   FILTER  REGULATOR    PRESSURE SWITCH  1 BAR           GAS 2   SLOPE           FILTER                   348 ON BOARD GAS SYSTEM             MANIFOLD           
11.  The output of V4 is then fed into V2  which either vents the gas to  the weir area  or feeds it via V3 into the sample path via the first tee junction     Wash solution is controlled by V1 which allows recirculation of the wash  or directs it  to the probe     Calibration solution is controlled by V5 which recirculates it or directs it via V3 into  the sample path via the first tee junction     Slope solution is controlled by V6 which recirculates it or directs it into the sample  path via the second tee junction     Fluid flow is controlled by two pumps  The sample waste pumps the excess reagent  which collects in the weir to waste via P2 and the outflow from the sample block to  waste via P5  P2 and P5 are on the sample pump roller assembly     The three reagents  wash  cal and slope are pumped by the P1  P3 and P4 tubes on the  reagent pump roller assembly     Sample positioning is controlled by SD1 and SD2 which are optical detectors  For  short samples which can result in the auto split sample mode being initiated  the Hct  sensor acts as a sample detector     Electronic system    Please refer to Figure 4 when reading the following description    The instrument is under software control from a microprocessor which executes the  program resident on the plug in ROM card  All associated CPU circuitry  chip    decoding  RAM  interrupt control etc  is located on the CPU board  This board also  provides interfacing to the display module  printer  keypad and data ports     106
12.  a multiplexer  board  a probe interface board  a display module and a printer  The amplifier board  and multiplexer board fix together to form an amplifier assembly     The CPU board is mounted on the display moulding  The power supply interface  board is mounted at right angles to the CPU board and plugs directly into it  through a  slot in the main body moulding  The display module and keypad fit into the display  the display module moulding which fits to the top of the main body moulding  The  amplifier assembly is integral with the electrode block  and the probe interface is  integral with the probe assembly  The printer occupies the top right hand corner of the  main body moulding     106122 Rev A 10 96 6    INSTRUMENT DESCRIPTION       3 3    3 4    The instrument software is incorporated in a ROM card which is accessible through a  slot in the top of the instrument  It plugs directly into the CPU board  and the slot is  sealed with a flexible rubber strip     Hydraulics System  Please refer to Figure 3 when reading the following description     The main hydraulics system consists of a perspex manifold mounted on the front of  the main body moulding  The solenoid valves which control the various reagents and  gases are mounted directly onto the manifold  Tubing systems then direct the reagents  and gases to the appropriate points in the probe and electrode block     Calibration gases are fed into V4 which selects the appropriate gas required for the  current operation 
13.  be performed     Note  When carrying out any procedure which involves handling of printed circuit  boards  anti static precautions should be taken     4 2 Pre service Protocol  i  Access system set up in the main menu and initiate set up printout   67    11  On completion of the set up printout  remove and retain for future reference   ili  Disconnect instrument from the main electrical supply   iv  Carry out service procedure     v  Perform post service protocol     106122 Rev A 10 96 9    4 ASSEMBLY DISASSEMBLY       4 3 To replace the power supply board  Parts required   PSU board Cat No  106225  Note  Anti static precautions should be followed for this procedure   Power down the 348   Remove the nine screws holding the rear cover in place  Note that the two screws  fixing the bottom of the rear cover are longer than the rest  Remove the rear cover   Disconnect the transformer connection to the power board  PL11   Disconnect the  earth lead on the right hand side of the rear panel  as viewed from the rear   Remove    the four screws holding the rear panel in place  Remove the rear panel     Disconnect all remaining connections to the PSU board PLI PL6  PL8 PL10 and  PL12 PL 14     Remove the three screws holding the board in place at the ends of each of the three  support brackets     Remove the board carefully  ensuring that none of the components on it foul against  the support brackets  The PSU board can now be replaced     106122 Rev A 10 96 10    ASSEMBLY DISASSEMBLY
14.  module CPU  PL1    5v  display  1  N C 2  Ov digital 3  Display Module CPU  PL3   Ov digital 1  Display data bit 7 2  Ov digital 3  Display data bit 6 4  Ov display 5  Display data bit 5 6  Ov digital 7  Display data bit 4 8  Ov digital 9  Display data bit 3 10  Ov digital 11  Display data bit 2 12  Ov digital 13  Display data bit 1 14  Ov digital 15  Display data bit 0 16  Ov display 17  Control bit 1 18  Ov display 19  Control bit 2 20  Ov display 21  Control bit 3 22  Ov display 23  Control bit 4 24  Control bit 5 25  N C 26    Note  All Ov digital pins are linked on the CPU board    Schedule 12   CPU to printer    Printer signal CPU  PL2   Control line 1 1  Control line 2 2  Control line 3 3  Control line 4 4    106122 Rev A 5 96 56    INTERCONNECTIONS       Schedule 12   CPU to printer cont   d           5v  printer    5v  printer    5v  printer   Dot 8   Dot 7   Dot 6   Dot 5   Dot 4   Dot 3   Dot 2   Dot 1  Control line 5  Control line 6  Control line 7  Control line 8   5v  printer    5v  printer   Ov digital  Position sense output    Note  All 5 volt  printer  pins are lined on the CPU board  Schedule 13   CPU to data ports    Data port 2 signal  N C   Tx data   Rx data   DTR   Ov digital   N C   N C   CTS    5v digital    Data port 1 signal  N C   Tx data   Rx data   DTR   Ov digital    106122 Rev A 5 96 57    D I ON L    11  12  13  14  15  16  17  18  19  20  21  22  23    CPU  PL4   1          I OO Lh EL D    CPU  PLS   1    Ln BR    LA    8 INTERCONNECTIONS    
15.  now be eased forward to give access to the solenoid assemblies  If necessary  the  gas lines can be disconnected from the manifold to improve access  Remove each of  the solenoid assemblies by peeling off the label covering the retaining screws and  removing the three retaining screws per solenoid assembly     When replacing the manifold  ensure that the sealing strip along the top and down the  right side is in place  Also ensure the solenoid assemblies are plugged into the correct  ports on the PSU board  and the gas lines connected correctly  The line from the 2  should connect to the uppermost of the two gas ports     106122 Rev A 10 96 29    4 ASSEMBLY DISASSEMBLY          8 673271   i  MANIFOLD  IG  673 278  SOLENOID       GAS FILTER FEEK TUBING  ASSEMBLIES    106122 Rev A 10 96 30       4 ASSEMBLY DISASSEMBLY  4 19 To replace the inlet sample detector and pre heater assembly  Parts required   Sample detector  inlet  Cat No  673266  Pre heater assembly Cat No  105671  Power down the instrument   Disconnect the pre heater from the probe carriage and the manifold  Remove the  sample detector cap from the front of the electrode block  exposing the pre heater  retaining screw  Unscrew this screw and remove the perspex pre heater cover and the  pre heater assembly  Grip the protruding part of the sample detector and pull it  forwards to remove it  It can then be replaced   4 20 To replace the outlet sample detector    Parts required   Sample detector  outlet  Cat No  673359
16.  of continuous product improvement and the right to change  prices  specification  equipment and maintenance procedures at any time  without notice  is  reserved     The 348 Analyzer is classed as IEC Type B equipment  Class I Equipment providing an    adequate degree of protection against electric shocks particularly regarding allowable leakage  currents and reliability of the protective earth connection      106122 Rev A 10 96  ii     CONTENTS       Page  1  Introduction 1  2  Controls and Services  2 1 User controls and displays 2  2 2 Other connections and services 2  2 3 Rear panel   selecting voltages 4  3  Instrument description  3 1 General 6  3 2 Structural 6  3 3 Hydraulic system 7  3 4 Electronic system 7  3 5 Gas system 8  4  Assembly disassembly  4 1 Introduction 9  4 2  Pre service protocol 9  4 3 To replace the PSU board 10  4 4    To replace the gas restrictor tubing 13  4 5 To replace the regulator pressure switch assembly 15  4 6 To replace the CPU board 18  4 7 To replace the printer 22  4 8 To replace the display module 22  4 9 To replace the keypad 22  4 10 To replace the motor gearbox assembly 24  4 11 To replace the fan 24  4 12 To replace the BP sensor 24  4 13 To replace the tube tensioners 24  4 14 To replace the transformer assembly 26  4 15 To replace the probe lever 27  4 16 To replace the probe bracket 27  4 17 To replace the probe sensor 27  4 18 To replace the manifold and solenoid assemblies 29  4 19 To replace the inlet sample detector and pr
17.  section 4 3 to remove the PSU board     Disconnect the two pressure switch connectors  Unscrew the four retaining screws   note their different lengths  holding the electrode block in place  Remove the  electrode block assembly  Unscrew the four screws holding the electrode block cover  in place  After removing the cover the amplifier board is exposed  Undo the three  screws holding the amplifier assembly in place   The one nearest the ribbon cable  connector will need to be unscrewed further than the other two   Once loosened  the  amplifier board can be extracted using the tool provided  The two lugs in the tool  locate in the two semi circular holes at either side of the amplifier assembly  The  assembly can then be eased out of the electrode block and replaced     106122 Rev A 10 96 33    4 ASSEMBLY DISASSEMBLY                105171  Amplifier Assembly  Screws in  3 positions  105178  Electrode Block Assembly    106122 Rev A 10 96 34    4 ASSEMBLY DISASSEMBLY       4 22 Post Service protocol    On completion of any of the procedures described which necessitate powering down  the 348  the following steps should be taken     i    Reconnect the 348 to the supply    ii  Select print set up in the system  set up part of the main menu  ff 67   Check  that the set up is the same as prior to the service procedure  If not  enter the  relevant set up parameters as required    iii  Once the 348 has reached operating temperature and calibrated measure three  levels of IC  eg Certain
18. 02 B23  B24 Port 103 B24  B25 Probe   ampoule position detector output B25  B26 Oc digital B26  B27 N C B27  B28 Voltage threshold B28  B29  5v analogue B29  B30  5v analogue B30  B31 Ov analogue B31  B32 Temp4 B32    Note  The following pins are all linked  separately by function  on both the CPU and PSU      5v digital  Ov digital   5v analogue   5v analogue  Ov analogue   12v    12v    22v    Schedule 7   PSU to solenoids    Solenoid signal PSU  PL8    12v 1  pH Cal on off  V5  2   12v 3  Wash on off  V1  4    106122 Rev A 5 96 54    INTERCONNECTIONS       Schedule 7   PSU to solenoids cont   d     12v   Vent on off  V2    12v   Gas select on off  V4      12v   pH Cal gas select on off  V3    12v   pH slope on off  V6     PSU  PL9   1    2  3  4  PSU  PL10   1    2  3  4    Note  All  12v pins are linked on the PSU board    Schedule 8   PSU to transformer    Transformer   18 VAC  secondary a   18 VAC  secondary a   18 VAC  secondary b   18 VAC  secondary b   18 VAC  secondary c   18 VAC  secondary c   System ground   N C    Schedule 9   PSU to pump motors  Pump motor signal    Reagent pump drive voltage  Ov  12v supply     Ov  12v supply    Sample waste pump drive voltage  Schedule 10   PSU to gas chassis  Gas chassis signal   Cal pressure switch    Slope pressure switch   5v digital    106122 Rev A 5 96    PSU  PL11   1    GO IN Lh EL D    PSU  PL12   1  2    PSU  PL13   1  2    PSU  PL14   4  9  10    55    8 INTERCONNECTIONS       Schedule 11   CPU to display    Display
19. 0Secs                     106122 Rev A 10 96    45    HYDRAULICS       7 2 5 Full 1 Point Sequence        Step  Sequence  Reference      1  Cal pH Lytes   7 2 11      2 Gas Cal   7213      3  CalWash   7215          Step  Sequence  Reference      1 Cal pH Lytes 7 2 11      2 Slope pH Lytes 7 2 12      3 Gas Cal 7219       4  Gas Slope 7 214      5  Cal Wash 7 215                Step  Seguence   Reference      1  Gas Cal   7213      2  CalWash   7215          Step  Seguence   Reference      1  GasCal   7 213      2   GasSlope   7214      3  CalWash   7215             Step  Sequence  Reference      1   CalpH Lytes   7 2 11      3   Cal Wash   7215    7 2 10 pH Lytes 2 Point  Sequence    Step  Sequence  Reference      1   CalpH Lytes   7 2 11      2   SlopepHiytes   7 2 12      3  Cal Wash   7 2 15      106122 Rev A 10 96                                                             7 HYDRAULICS  7 2 11 Cal pH lytes Sequence    Step Action   Pumps   Solenoids End State        Sample  Reagent ivi  V2  V3  V4 VS  V6      1   AspirateCal   1 808   2 025  Off Off Off Off On Off     4Secs      2   Aspirate Air   1 808   2 025  Off ofrjoff offjoffjoff    3Secs      3   Aspirate Cal   1 808   2 025  off ofrjoff offjon off  18ec      4   Aspirate Air   1 808   2 025  off ofrjoff offjoffjoff     1Sec      5 12   Repeat steps 3 4 4 times            13   Aspirate Cal   1 808   2 025  Off OffJOffJOff On Off     1Sec      14   Aspirate Air   1 808   2 025  Off ofrjoff offjoffjoff   11Secs     
20. 122 Rev A 10 96 7    INSTRUMENT DESCRIPTION       3 5    The CPU board receives power from the Power Supply board and provides signals  interfaces to the rest of the system  The Power Supply board converts AC power to  the DC power required by the electronic circuitry and also provides interfaces for the  fan  the reagent and sample motors  all the solenoids  the probe assembly  the BP  sensor and the electrode block assembly     All analog signals in the system are fed via a multiplexer to the A D converter which  is situated on the Power Supply board     Gas chassis  Please refer to Figure 5 when reading this section     The two gas mixtures required  cal and slope  are supplied in two gas cartridges   These cartridges screw into a regulator pressure switch assembly  The pressure  switches activate at a level of 1 bar  and this prompts the user via the display to  change the cartridges  The regulator is pre set to 5psi  The gases then pass through a  filter  which is part of the regulator pressure switch assembly  into a restrictor  comprised of a length of peek tubing  The gases then enter the manifold via a further  filtered connection     106122 Rev A 10 96 8    4 ASSEMBLY DISASSEMBLY       4 1 Introduction  The following description of how to disassemble the 348 should be used in  conjunction with the relevant figures and exploded views  Before carrying out any  procedure which reguired power to be disconnected from the 348 the pre service  protocol  section 4 2  should
21. 3055 Block thermistor assembly 1  473056 Detector plunger 1  473057 Block connector 1  570000 Rotor knob kit 1  673366 Solenoid screw labels pk of 10  673367 PCB brackets pk of 3  673368 Sample detector access cover 1  673369 Rubber feet pk of 4  673370 Power inlet 1  105260 Rear cover 1  106193 Gas cartridge cover 1  105170 Gas regulator pressure switch assembly 1    6 2 Engineering Spares Kit    As most parts are common with the 248  there is not a complete engineering spares  kit  There is an addition kit  catalogue number 108571  This kit should be used in  conjunction with either    673279 Engineering Spares Kit  or    673363 248 Spares Kit  level 1     The contents of the addition kit  108571 are     Catalogue number Description   105170 Gas regulator  pressure switch assembly   105171 Amplifier assembly   105177 Memory card kit   105185 Gas restrictor kit   105673 Pump tube kit   105672 Bottle tubing kit   105671 Pre heater kit    106122 Rev A 10 96 42    7 HYDRAULICS       7 1 Introduction   The hydraulic sequences are set out as a series of tables  Sub sequences are given in detail  and overall sequences as a set of sub sequences  For example the full 1 point sequence is  given as a set of references to the sub sequences that make it up    The numbers in the columns referring to the sample and reagent pumps are voltages  The  sample pump voltage is always negative  The reagent pump voltage is always positive except  for a small number of occasions when the pump runs 
22. 348    pH Blood Gas Electrolytes   Haematocrit Analyzer    Service Manual    Chiron Diagnostics    106122 Rev A 10 96    The 348 Blood Gas Analyzer is designed for fast and accurate measurement of whole blood     The 348 measures pH  pO2  pCO2  Na  K  Hct and either Ca or Cl and uses a sample volume  of 95ul     The service manual contains complete instructions for servicing the 348   Warning    The 348 is designed to be grounded through the power supply lead  line cord  for safe  operation  For the safety of operating personnel make sure that the instrument is only  connected to 3 prong sockets  outlets  that have an effective earth connection  If you are in  any doubt as to the safety of your electrical supply system consult a competent qualified  electrician     There are no user replacement parts within the instrument  Do not remove the covers from  the 348     Chiron Diagnostics and their Authorized Distributors and Agents consider themselves  responsible for the effects on safety  reliability and performance of the 348 only if     i  Assembly operations  extensions  re adjustments  modifications or repairs are carried  out by persons authorized by them     11  The electrical installation of the relevant room complies with IEC reguirements or the  local regulatory code  and    111  The eguipment is used in accordance with the instructions for use     The information contained in this manual was correct at time of going to print  However   Chiron Diagnostics policy is one
23. PL6    TO SK2  106195    CPU Board    Note spacer    106122 Rev A 10 96 21       4 ASSEMBLY DISASSEMBLY  4 7 To replace the printer  Parts required   Printer head Cat No  673267  Follow the procedure described in section 4 6 to remove the CPU board  Once the  CPU board is removed  the printer head can be removed by unscrewing the three  remaining screws on the printer tray  and then removing the printer head from the  printer tray and replacing   4 8 To replace the Display Module  Parts required   Display Module Cat No  673263  Follow the procedure described in section 4 6 to remove the CPU board  Unscrew the  two pillars at the top of the display board  and remove the two screws at the bottom   The display module can now be lifted out and replaced   4 9 To replace the keypad    Parts required   Keypad Cat No  673270  Follow the procedure described in section 4 6 to remove the CPU board  Remove the    eight nuts and washers which retain the keypad in place  The keypad can now be  removed from the front panel and replaced     106122 Rev A 10 96 22    4 ASSEMBLY DISASSEMBLY           673270  Keypad    673263  Display Board       673267  Printer Head    106122 Rev A 10 96 23       4 ASSEMBLY DISASSEMBLY  4 10 To replace the motor gearbox assemblies  Parts required   Motor gearbox Cat No  478666  Power down the 348  Remove the pump tube cassette from the relevant rotor cage  Unscrew the rotor screw  in the end of the rotor cage  Slide the rotor cage off the motor shaft  Remove th
24. The bracket can then be replaced   4 17 To replace the probe sensor    Parts required   Probe sensor Cat No  673284    Remove the probe bracket assembly as described in section 4 16  The probe sensor  can be removed by unscrewing the single retaining screw on the left hand side of the  assembly  when viewed from the rear   and removing the sensor assembly for  replacement     106122 Rev A 10 96 27    4 ASSEMBLY DISASSEMBLY             673 284  PROBE SENSOR PCB       673 286  PROBE BRACKET    NOTE  BLACK DOTTED LINE  ON CABLE DESIGNATES PIN 1   TO BE POSITIONED TO THE  RIGHT     106122 Rev A 10 96 28    ASSEMBLY DISASSEMBLY       4 18    To replace the Manifold or Solenoid assemblies  Parts required     Manifold Cat No  673271  Solenoid Cat No  673278    Remove the reagent bottles from the front of the instrument  Place a tissue under the  ends of the reagent tubes to soak up excess reagent  Using the maintenance option in  the main menu  select the prime option   32      Remove the gas cartridges  Power down the 348  Follow the procedure described in  section 4 3 to remove the rear cover and panel  Disconnect the three solenoid  assemblies from the PSU board  Remove the drip tray connector to the manifold and  the pre heater connector  Remove the two tubing cassettes  sample waste and  reagent  from the manifold     Remove the reagent tubing and the waste bottle  Unscrew the six nylon screws  holding the manifold solenoid assembly in place  The manifold solenoid assembly  can
25. age reference  VRefBuf   Ov analogue  Voltage offset  Voffset   Ov analogue  Mux output  AnalogIn   Ov analogue  Mux select  MuxSel 2   Ov analogue  Ov analogue  Ov analogue    Signal   5v digital   5v digital   5v digital    52    PSU  PL14   1    3  5  6    PSU  PL5   1    GO IN Lh EL D    11  12  13  14  15  16  17  18  19  20    PSU  PL6   1  2    PSU  PL7   Al  A2  A3    8 INTERCONNECTIONS       Schedule 6   PSU to CPU cont   d         A4 Ov digital A4  AS Ov digital AS  A6 Ov digital A6  AT  12v A7  CPU  SK7  Signal PSU  PL7   A8 Ov digital A8  A9  12v A9  A10  22v A10  All N C All  A12 100 A12  A13 101 A13  A14 102 A14  A15 103 A15  A16 104 A16  Al7 105 Al7  A18 106 A18  A19 107 A19  A20  Sv digital A20  A21  Sv digital A21  A22 N C A22  A23 Disable P A23  A24 Probe   home position detector output A24  A25 Probe   syringe position detector output A25  A26 Ov digital A26  A27 SD1 output A27  A28 SD2 output A28  A29  5v analogue A29  A30  5v analogue A30  A31 Ov analogue A31  A32 Voltage reference  VRefBuf  A32  Bl  5v digital Bl  B2  5v digital B2  B3  5v digital B3  B4 Ov digital B4  B5 Ov digital B5  B6 Ov digital B6  B7  12v B7  B8 Ov digital B8  B9  12v B9  B10  22v B10  B11 N C B11    106122 Rev A 5 96 53    8 INTERCONNECTIONS       Schedule 6   PSU to CPU cont   d         B12 Se10 B12  B13 Sell B13  B14 Se12 B14  B15 Se13 B15  B16 Sel4 B16  B17 Sel5 B17  B18 Se16  not used  B18  B19 Se17  not used  B19  B20 ADDCLK B20  B21 ADCDATA B21  B22 Port 101 B22  B23 Port 1
26. are held in place with three screws removable from the rear of the bulkhead   The three position tensioner is located on the left hand side of the bulkhead when  viewed from the rear  and the two position tensioner is more central to the bulkhead   They can then be reached     To replace the transformer assembly  Parts required   Transformer assembly Cat No  105223  Follow the procedure described in section 4 3 to remove the rear panel  Remove the  nut holding the earth lead in place  Remove the two nuts retaining the voltage input    selector  Undo the four screws retaining the transformer in place  The transformer  assembly can now be replaced     105223  Transformer Assembly       106122 Rev A 10 96 26       4 ASSEMBLY DISASSEMBLY  4 15 To replace the probe lever  Parts required   Probe lever Cat No  673285  First remove the probe carriage by disconnecting it from the pre heater input  and then  raising the probe to its topmost position and sliding the probe carriage out  The probe  lever can then be removed by squeezing the two sides together sufficiently to release  the lever  It can then be replaced   4 16 To replace the probe bracket  Parts required   Probe bracket Cat No  673286  Follow the procedure described in section 4 3 to remove the rear cover and panel   Disconnect the front cable from the PSU board  Unscrew the three retaining screws  holding the probe bracket in place and remove the bracket  sliding the flat cable  connector through the hole in the bulkhead  
27. backward and then the voltage is  negative     7 2 Sequences    See pages 45   51     106122 Rev A 10 96 43       7 HYDRAULICS  7 2 1 Sample Sequence    Step JAction   Pumps     Solenoids End State         Sample Reagent VI V2  V3  V4  VS  Vp       1   Aspirate   2966   Of  orrforororor om  38        2   Aspirate   1 374 Off   Off   Off   Off   Off   Off  Off   SD1 detects LE       3   Aspirate   1 374 0ff   Off       Off  Off  Off   Off   Off   Off  SD1 detects TE       4   Measure Off Off       Off   Off   Off   Off   Off   Off   End of Measure       5   Wash                               Note   For step 3 the sample motor alternates between 1 374 and off     For step 5 see section 7 2 4    7 2 2 QC Sequ     Step  Action     _      1   Aspirate      2   Aspirate    3   Aspirate    4   Measure    5   Wash             Note   For step 5 see section 7 2 4    7 2 3 Hct Slope Sequence    Step  Action      5 Wash         __       1   Aspirate    2   Aspirate    3   Aspirate    4   Measure                           SD1 detects LE    SD2 detects LE    3 Secs     End of Measure         SD1 detects LE      3 Secs  End of Measure    ence   Pumps   Solenoids    fendstate     Sample Reagent VI V2  V3  V4  VS  Vp   2 966 Off   Off Off   Off Off   Off   Off   2 966 Off   Off   Off   Off  Off   Off   Off   2 966 Off       Off   Off   Off  Off   Off   Off   Off Off       Off   Off   Off  Off   Off   Off  EE     Step  Action   Pumps   Solenoids   EndStte    Sample Reagent VI V2  V3  V4  VS  V
28. d  operator interaction are performed via a multiline  40 character vacuum fluorescent  display and a numeric keypad     The 348 is designed for fast  accurate determination of pH  pO2  pCO    Na  K  Hct and  either Ca or Cl  It is also capable of measuring Barometric Pressure  Certain  calculated parameters are also available based on the measured data     Parameter Symbol   Actual bicarbonate HCO  act   Standard bicarbonate HCO  std   Base excess  extra cellular fluid  BE  ecf    Base excess  blood  BE  B    Total carbon dioxide ctCO    Adjusted calcium Ca    7 4  1   Anion gap AnGap 2   Oxygen saturation OSAT   Oxygen content OCT 3   Alveolar arterial difference pO   A a  4   Arterial alveolar ratio pO   a A  4   Oxygenation ratio pO   a F10   4   Estimated haemoglobin ctHb  est  5  Notes     Available only if Ca is fitted      Available only if CI is fitted   3  Utilises tHb if entered  otherwise uses tHb  est   If neither estimated or entered tHb is  available then OCT is not available   4  Available only if FO  is entered   De Is overridden by entered tHb    Nie    106122 Rev A 10 96 1    CONTROLS AND SERVICES       2 1    2 2    User controls and displays  refer to Figure 1   Alpha numeric display    Multi line 40 character vacuum fluorescent display for presentation of results   operator options and status information     Printer    32 character dot matrix thermal printer for recording results  calibration and set up  data     Keypad    15 key keypad consisting of 10 
29. e  locating pin from the motor shaft  Remove rear cover  panel and PSU as described in  section 4 3  Unscrew the two fixing screws  one at each side of the motor gearbox  assembly  Withdraw the assembly through the bulkhead and replace   4 11 To replace the fan  Parts required   Fan Cat No  474745  Follow the procedure described in section 4 3 to remove the rear panel  Disconnect  the fan from the PSU board  Unscrew the four retaining screws and remove the fax  and replace   4 12 To replace the BP sensor  Parts required   BP sensor Cat No  813014001  Follow the procedure described in section 4 3 to remove the rear cover  panel and  PSU board  Unscrew the two retaining screws and remove the BP sensor and replace   4 13 To replace the tube tensioners    Parts required   Tube tensioning kit Cat No  673274  Follow the procedure described in section 4 3 to remove the rear cover  panel and    PSU board  Follow the procedure described in section 4 4 and 4 5 to remove the gas  cartridge assembly     106122 Rev A 10 96 24    4 ASSEMBLY DISASSEMBLY       473 765 arrow detail onside of fan    WRITING FACING up Wes  LERGA   a a    REMOVE 4 FIXING SCREWS           REMOVE 2 i      FIXING SCREWS V    478 666  MOTOR GEARBOX  lt        8P SENSOR    REMOVE 2  FIXING SCREWS       REMOVE 3 FIXING  SCREWS per tensioner           TENSIONING    KIT    106122 Rev A 10 96 25    ASSEMBLY DISASSEMBLY       4 14    The two tube tensioners  one with three tube positions and one with two tube  positions  
30. e heater assembly 31  4 20 To replace the outlet sample detector 31  4 21 To replace the amplifier board 33  4 22 Post service protocol 36  continued    106122 Rev A 10 96  iii     Contents cont   d               Page   5  Troubleshooting   5 1 General 37   5 2 Power supply checks 37   5 3 Status indicator check 37   5 4 Electrode problems 37   5 5 Hydraulic problems 38   5 6 System re starts 39  6  Spares   6 1 Ordering information 42   6 2 Engineering Spares Kit 43  7  Hydraulics   7 1 Introduction 44   7 2  Sequences 45  8  Interconnections 52    Figures    Figure 3 Hydraulic system   Figure 4 Electronics system   Figure 5 Gas system   Figure 6 AC power supplies   Figure 7 PSU layout   Figure 8 CPU layout  top    Figure 9 CPU layout  bottom    Figure 10 Amplifier layout   Figure 11 Keypad circuit diagram  Figure 12 Probe sensor circuit diagram  Figure 13 Amplifier circuit diagram  Figure 14 Multiplexer circuit diagram  Figure 15 PSU circuit diagram   sheet 1  Figure 16 PSU Circuit Diagram   sheet 2  Figure 17 PSU circuit diagram   sheet 3  Figure 18 PSU circuit diagram   sheet 4  Figure 19 PSU circuit diagram   sheet 5  Figure 20 CPU circuit diagram   sheet 1  Figure 21 CPU circuit diagram   sheet 2  Figure 22 CPU circuit diagram   sheet 3  Figure 23 CPU circuit diagram   sheet 4  Figure 24 CPU circuit diagram   sheet 5    106122 Rev A 10 96  iv     1  INTRODUCTION       1 1 Introduction    The 348 is a direct reading blood gas electrolytes haematocrit analyzer  Results an
31. following information to your  Chiron Diagnostics distributor     348 serial number   Catalogue number of part  Cat    Description   Quantity required    This will ensure that your order is dealt with quickly and efficiently   The number shown in the third column  Quantity  is the quantity supplied against the stated    catalogue number  If the quantity is greater than 1  only multiples of that quantity can be  supplied     Catalogue number Description Quantity  478648 Fuse pack UL CSA 2 per pk  478916 Fuse pack IEC 2 per pk  478937 Voltage select bobbin 1  106195 CPU board 1  106225 PSU board 1  105171 Amplifier board 1  673263 Display module 1  105177 Memory card 1  673284 Probe sensor assembly 1  673285 Probe lever 1  673286 Probe bracket 1  673266 Sample detector  inlet  1  673359 Sample detector  outlet  1  473745 Fan 1  673267 Printer head 1  673269 Printer cover 1  673268 Printer cradle 1  478666 Motor gearbox kit 1  478664 Rotor kit 1  814013001 BP sensor 1  673278 Solenoid assembly 1  673270 Keypad 1  673271 Manifold 1  105178 Electrode block assembly 1  105185 Gas restrictor kit 1  673274 Tube tensioner kit 1  673265 Memory card sealing strip 1  105223 Transformer and mains inlet assembly ih    106122 Rev A 10 96 41    6 SPARES       673281 Main bulkhead 1  673282 Main cover 1  673283 Display moulding 1  673275 Hardware kit 1  673276    O    ring kit 1  106122 348 service manual 1  105227 Display window 1  473050 Block extension spring 1  473051 Catch moulding 1  47
32. hich version is appropriate for your  customer    3 2 Structural    The casework of the instrument is a combination of plastic mouldings and sheet  metalwork  The main body structure is a plastic moulding which has mounted on it  the main hydraulic components   solenoid valves  pump  etc  The electrode block is  mounted to the front of the moulding as is the probe assembly     The power plate is of folded sheet metalwork fitted to the rear of the gas chassis  This  plate has the main power inlet and transformer fixed to it     The gas chassis is of sheet metal construction with two regulator pressure switch  assemblies mounted on the left had side  A plastic moulding with two gas cartridge  guide tubes fits into the gas chassis and covers the right had side of the instrument   The two gas cartridges slide into the two access tubes and are screwed into position     The main electronic components are mounted on the main body moulding at the top of  the instrument  The keypad and display are also mounted on the display moulding  which fits to the top of the main body moulding     A cover with a viewing window is hinged to the sides of the main body moulding   This cover can be raised to give access to the system for maintenance and  troubleshooting  The viewing window allows for the sample path visibility  During  aspiration of the sample path is illuminated     The electronic system consists of the following     The CPU board  a power supply interface board  an amplifier board 
33. lock temperature sense voltage    Note  pins 7 and 0 are linked on the PSU board    Electrode block signal   SD1 LED voltage supply   SD2 LED voltage supply   SD1 voltage on off control   SD2 LED voltage on off control  SD1 sense voltage   Ov analogue   SD2 sense voltage   Ov analogue    Note  pins 6 and 8 are linked to the PSU board  Schedule 2   PSU to BP sensor    BP sensor signal   BP sensor voltage supply  BP sensor sense voltage  Ov analogue    Schedule 3   PSU to probe    Probe signal   Voltage reference to thermistor  Thermistor sense voltage   Syringe position detector output  Ov digital   Home position detector output  Ampoule position detector output  Ov digital    Note  pins 4 and 7 are linked on the PSU board    106122 Rev A 5 96 51    PSU  PL1   1          IA Un       D               PSU  PL2   1    GO IN RV      PSU  PL3   1  2  3    PSU  PL4   1    ANM ELM D    INTERCONNECTIONS       Schedule 4   PSU to amplifier PCB    Amplifier board SK5  1    AN  amp     D    7   8   9   10  11  12  13  14  15  16  17  18  19  20  21  22  23  24  25  26    Schedule 5   PSU to fan  Fan signal  Ov  12 volt supply    12v  Schedule 6   PSU to CPU  CPU  SK7    Al    A2  A3    106122 Rev A 5 96    Signal   12v   12v    Hematocrit measure enable  HCTEN   Sample chamber LEDs control  LEDOFF     N C  N C    Mux select  Port 4 0   Mux select  Port 4 1   Mux select  Port 4 2   Mux select  MuxSel I    5v analogue   5v analogue   5v analogue   5v analogue  Ov analogue  Ov analogue  Volt
34. numeric keys 0 9    key    key  clear  c  key  decimal  point     key and paper feed key     The keypad is used to initiate instrument operations  enter data and respond to display  instructions     For full details of keypad display interaction see section 2 of the instruction manual   Probe lever   The probe lever can be raised to one of two possible sampling positions  syringe or  capillary  Presentation of the sample will automatically initiate the operational  sequence  A third position allows removal of the probe carriage assembly    Rear and side panel connectors  refer to Figure 2    Power   Input AC power connection incorporating fuses and voltage selection    Data output   2 data output ports  Port 1 and Port 2  Both are 9 way    D    type connectors  Port 1 isa  female connector for RS232 communication only  and Port 2 is a male connector for  use as both RS232 communications  and a bar code reader     Gas chassis    Two access holes for insertion of cal and slope gas cartridges     106122 Rev A 10 96 2    2 CONTROLS AND SERVICES       Vacuum  Fluorescent Display               Paper  Advance  Numeric  Operating  pa Keypad  Probe Lever   lift to first position to sample from  ampules  Vacutainers     vials and other open top  containers  Lift to second position to sample trom  syringes and capillaries   Figure 1  Data Ports  Mi  9 way D line si  K Status  jez  Or     indicators    N  o OM  i I  Instrument Ground  IEC Symbol Test Point  advising user  to refer to EN 
35. om the main instrument  Thread the earth strap through the hole in the main  moulding  Place the instrument cover to one side  ensure the two bearing bushes are  retained in place on the cover   Lay the sub assembly face down on a protective  surface to prevent scratches occurring on the front panel  Remove the earth  connection to the stud on the printer tray  Remove the metal grill from the board by  unscrewing the four hex nuts on the two data ports  Remove the six screws holding  the CPU board in place  Disconnect the 26 way ribbon cable at the top left hand  corner of the board and the two power connections in the centre at the right hand side  of the board  Disconnect the keypad connector at the bottom left hand side of the  PCB  Disconnect the printer head connector sliding the outer cover of the connector  towards the bottom of the CPU board and then sliding the connector tail out  Lift the  CPU board clear of the sub assembly  Note that the screw in the bottom left hand  corner of the board is longer than the others and passes through a spacer to the printer  assembly  The CPU board can then be replaced     106122 Rev A 10 96 18    4 ASSEMBLY DISASSEMBLY          673265    Memory Card Sealing Strip  be    II       673269    Printer Cover       673268  Printer Cradle    106122 Rev A 10 96 19    4 ASSEMBLY DISASSEMBLY              GREEN   YELLOW  SCREENING CABLE    DISPLAY MOULDING  ASSEMBLY    106122 Rev A 10 96 20    4 ASSEMBLY DISASSEMBLY          14 WAY JUMPER  TO 
36. out of range readings  a    series of steps should be taken     a  Visually inspect the whole electrode area for signs of KC1 leakage  Remove the  electrodes and ensure that no leaks have occurred resulting in alternative  Examine the electrode contact for signs of    conductive paths for signals     corrosion     106122 Rev A 10 96    36    TROUBLESHOOTING       Electrode problems cont   d            5 5    b     c     d     e     Remove any bubbles from the Reference Electrode  This can be done by tapping  or shaking the electrode to manipulate the air bubble into the cassette chamber   The bubble can also be removed by unscrewing the nafion inner by means of the  small hexagonal tool in the electrode box and allowing the KC1 solution to flow  up and displace the bubble     If the previous two steps are unsuccessful and the pH and electrolyte have  sufficient fill solution in them  then deproteinizing and conditioning should be  carried out  see Section 4 6 of the Instruction Manual      Note  After deproteinizing and conditioning the electrodes may take up to 2  hours to return to stable operation     The troubleshooting option   31  should be used to determine if the electrodes  are performing within specification  see Section 5 7 of the Instruction Manual    Large negative millivolt readings are usually indicative of bubbles in the  reference electrode  If the test results indicate satisfactory electrode performance  and the standardization of the instrument is persisten
37. p   2 966 Off   Off Off   Off Off   Off   Off   2 966 Off      Off   Off   Off  Off   Off   Off   2 966 Off       Off   Off   Off  Off   Off   Off   Off Off       Off   Off   Off  Off   Off   Off   EE             Note   For step 5 see section 7 2 4  106122 Rev A 10 96                      SD2 detects LE                  7 HYDRAULICS  7 2 4 Sample Wash Sequence    Step  Action   Pumps    Solenoids End State       Sample  Reagent  VI IV2  V3  v4 VS  V6      1   WashProbe   Off   7 523  On  Off Off Off Off Off    1 5Secs      2 Clear Block   7 523   Off  Ofr off off ofr ofrjoff   4Secs      3 Prime Wash   7 523   7 523  On  Off Off Off Ofr Ofr  1 LE or 8 Secs      4 Clear Block   7 523   Off  Ofr off off ofr offjoff   4Secs      5   Refresh Slope   7 523   7 523  ofrjofr ofr ofrjoff  On  0 5Secs      6 Clear Block   7 523   7 523  Ofr off off ofr offjoft   1Sec      7 Refresh Cal   7 523   7 523  Off Off Off Off On  Ofr  0 5Secs      8 Clear Block   7 523   7 523  Off off off off offjoff   2Secs      9 Wash   7 523   7 523  On oOff off Off off ofr  0 5Secs      10 Air   7 523   7 523  ofrjofrjofr ofr off off  05Secs      11 16 Repeat steps 9 10 3 times     oe      17 Wash   7 523   7 523  On off off Off ofr ofr  0 5Secs      18 Clear Block   7 523   Off  On OffjOff OffJOft Off  18ec      19 Clear Wash   7 523    2 025  On Off Off Off Off Off   2Secs      20  VentSlope Gas  Off   Off  Off On  Off On Off Off      4Secs      21 Clear Block   2 025   Off  Off On  OfEj On JOff OfE  1
38. re      8   Measure 2 749 Off _  Off  Off  On  Off Off Off  End of Measure      106122 Rev A 10 96                      7 HYDRAULICS       7 2 14 Gas Slope Sequence    Step Action   Pumps   Solenoids  End State         Sample  Reagent  VI IV2  V3  V4 VS V6        Remove Gas   7 523   Off  OfOfOfOflomon      10Secs               1  2   Vent Slope Gas   Off   Off  Off On  Off On  Off off  5 Secs  3  Prime Slope Gas  Off   Off  Off Off On On  Off Off    5 Secs  4 Aspirate Gas   2 749   Off   Off Off On   On  Off Off  End of Measure    5 Measure   2 749   Off      Off Off  On  On  Off Off  End of Measure                     Step Action   Pumps   Solenoids End State         Sample  Reagent  VI IV2  V3  V4 VS Vp      1 Clear Block   7 523   Off  OfflOffofofloflof       4Secs    2 Prime Slope   7 523   7 523  OffOfflOff OfflOffOn   0 5Secs    3 Clear Block   7 523   7 523  Ofr off offjofrjoffjoff      1sec    4 Prime Cal   7 523   7 523  Off Off Off Off On  Off  3 LEs or 5 Secs    5 Clear Block   7 523   7 523   Off Off Off Off Off Off  6 TEs or 6 Secs   6 Aspirate Air   7 523   7 523  Off Off Off Off off off  1 sec  7 Prime Wash   7 523   7 523  On Off Off Off Off Off  1 LE or 8 Secs    8 Wash   7 523   7 523  On Off Off Oft OffJOfE  0 5Secs    9 Air   7 523   7 523  Off off off ofr offjofr   0 5Secs    10 13   Repeat steps 8 9 2 times              14 Clear Block   7 523   Off  Onjoffjofrjoffjoffjoff      1Sec    15 Clear Wash   7 523    2 025  On Off Off Off Off Offj   2Secs    16
39. t hand corner of the  manifold will deliver reagent in the following sequence     Centre port   delivers cal buffer  Right port   delivers slope buffer  Left port   delivers wash    The gas paths can be checked by using the Run cal gas and Run slope  gas routines in the troubleshooting option   313 and  314   After the  initial pre cal wash has taken place and the sample pump is rotating  slowly  the probe can be opened and the probe tip inserted into liquid   a used QC ampoule is appropriate   A stream of bubbles can be  observed emanating from the tip of the probe  Turning off the gas at  the gas bottle and checking that the gas flow ceases will determine that  the correct gas is being delivered into the electrode block     Certain pump tube failures are obvious  eg tubes splitting  If  however   the failure is as a result of reduced flow rate in one of the tubes due to  wear  or blocked filters  then it will not be so obvious     Utilising the Run cal and slope buffers in the Troubleshooting option    311 and  312  and inspecting what occurs at the T junction in the  pre heater will give some good indications of pump tube condition   When the buffers are pumped into the block via the T junction  more  solution is delivered than the sample pump will take away  This results  in some flow back from the T junction towards the sample probe  If  this flow back does not happen  or is minimal  then the pump tubes  will need changing     5 6 System re starts    The 348 software con
40. tinually checks its own internal data store in case of corruption   It also monitors the incoming power status to achieve controlled recovery from  intermittent power interruption  brown outs  etc  Dependent on the condition under  which the breakdown occurred  the 348 will re start in a number of different ways     106122 Rev A 10 06    38    TROUBLESHOOTING       5 6 1    5 6 2    Cold start  Conditions under which this will occur     First time power up   Power up with new CPU board   Power up with failed on board battery   Power up with reset button held in   The reset button is located between the two data  ports on the rear panel   it must be held in until a double beep is heard      Status on restart    All settable options reset to default values  except factory set pO2 channel offset   Sample and QC number set to zero   Calibration will be two 2pt calibrations 10 minutes apart once the system has achieved  operating temperature    Tepid start    a  When powered up with a new version of software in which significant change  has been made  eg default correlation factors changed     Status on restart    All settable options reset to default with the following exceptions   BP calibration   Sample number   Real time clock   ID number   Service telephone number   Language   A 2pt calibration will be forced  Hct slope will be prompted     b  Conditions under which this will occur     When powered up with a new version of software in which no significant  change has happened
41. tion 4 3  the gas  cartridges and restrictor tubing as described in section 4 4     Remove the strengthening bar on the gas chassis by undoing the four screws which  retain it  This gives access to the four screws holding the gas cartridge moulding in  place  Remove the four screws holding this moulding in place at this end  remove the  two screws underneath the regulators holding the cartridge moulding assembly to the  base strut at the end  Pull the top of the moulding backwards and out from where it is  retained by the main moulding  Slide the moulding out far enough to give access to  both regulator pressure switch cables  Remove the required assembly by undoing the  three retaining screws holding it in place on the gas cartridge moulding     106122 Rev A 10 96 15    4 ASSEMBLY DISASSEMBLY          106122 Rev A 10 96 16    4 ASSEMBLY DISASSEMBLY           MAGNETIC  SCREWORIVER       106122 Rev A 10 96 17    ASSEMBLY DISASSEMBLY       4 6    To replace the CPU board  Parts required    CPU board Cat No  106195  Power down the 348     First remove the rear panel and the PSU board as described in section 4 3  Remove  the memory card from its slot beneath the rubber seal on the top of the display  moulding  Remove the six screws retaining the display printer keypad CPU sub   assembly  Remove the printer paper from the printer and slide the printer cradle and  cover up to remove them     Raise the instrument cover to the upright position  Pull the sub assembly forward   away fr
42. tly failing then the problem  is probably hydraulic     Frequent occurrences of unstable readings can be due to bad earth connections to  the electrode block door  Continuity between the main earth stud on the base    plate and the electrode door should be checked     N B  The door must remain closed in normal operation     Hydraulic problems    The main causes of hydraulic problems are leaks  blockages  solenoid failure or pump  tube failure     Various techniques can be utilised in checking for the different hydraulic problems     Leaks  These will generally be visually evident  In the case of small leaks     crystal build up in the area of the leak will occur     Blockages    The symptoms which could indicate a blockage would be the failure of    liquid to be present as expected during a hydraulic cycle  ie sample not  being aspirated during a sample cycle  pH buffer not being delivered to  the electrode block during calibration     If a blockage is suspected  then the techniques for clearing blockages  described in section 4 22 of the operators manual should be used     106122 Rev A 10 96 37    TROUBLESHOOTING       Hydraulic problems cont d          Solenoid  failure     Pump tube  failures     In order to check for solenoid failure  the different fluidic paths need to  be checked out     One method of doing this is to remove the grey connector which  connects the manifold to the pre heater tubing assembly  Initiate a  prime sequence   23   The three ports at the top lef
    
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