PDFファイル - 医薬品医療機器総合機構
Contents
1. 1000ppm 2 1 121 C 20 1 8 2 1 6 098925 BuBc 18 1 5 1 90 098918 BuBc 60 1 5 1 300 1 Tietz NW ed Fundamentals of Clinical Chemistry ed 3 Philadelphia WB Saunders 730 736 1987 2 Doumas BT Kwok Cheung PP Perry BW Jendrzejczak B McComb RB Schaffer R and Hause LL Candidate Reference Method for Determination of Total Bilirubin in Serum Development and Validation Clin2. Bu Bc RE Dy TC Bc Bu Bc 400 420nm Bu Bc 460nm Bu Bc 2 400 460nm Bu Bc Bu B
3. 2 4 TI 7 BSA FS 2 3 1 10 L 37 5 400 460nmm BuBc BuBc Bu Bc 0 0 1 1mg dL 0 19 mol L 0 0 0 3mg dL 0 5zmol L Bun 06 10 5mg dL 10 180zmol L Bc 0 0 0 6mg dL 0 10 zmol L mol L mg dLX17 1 110 25 85 1 2 40
4. 18 28 7 BSA 2 2 1 8 18 28C 18 60 2 8C 30 18 28C 18 28C 24 2 2
5. Bu Bc Bu Gilberts Crigler Najjar Bc Dubin Johnson Rotor Bu Bc 2 BuBc
6. y x Bu Serum n 88 r 0 984 y 0 97x 0 20 700 Bc Serum mg dL 27 24 Kx 21 18 lt 15 K 7 12 Le n 36 n 6 r 0 989 8 y 0 97x 0 17 0 0 3 6 9 12 15 18 21 24 27 mg dL 2 2 1 HBs HIV1 HITV2 HCV 2 3
7. 80 zg mL 033 2 1 10 zg mL 0 4 0 8 40 g mL 8 4 0 60 zg mL 03 0 5 Bc Bc PI Potential Interferent TBIL Bu PL 7 BSA BuBc yo BuBc 9 9 3
8. x x BuBc 098918 25 03 1506 21300AMY00515000 2015 6 3 2009 3 2 BuBc BuBc 25 2 TiO2 pH8 0
9. 95 1 Bu Bu 0 mg dL 0 mg dL Bu 0 6 mg dL 0 4 0 8 mg dL 20 4 CV 10 0 0 27 0 mg dL Bc Bc 0mg dL 0 mg dL Bc 0 4 mg dL 0 3 0 5 mg dL 20 4 CV 10 0 0 27 0 mg dL 2
10. Chem 31 1779 1985 3 Lauff JL Kasper ME Ambrose RT Separation of Bilirubin Species in Serum and Bile by High Performance Reversed Phase Liquid Chromatography Journal of Chromatography 226 391 402 1981 4 Young DS Effects of Drugs on Clinical Laboratory Tests ed 4 Washington D C AACC Press 1995 5 Friedman RB Young DS Effects of Disease on Clinical Laboratory Tests Washington D C AACC Press 1990 Tel0120 03 6527 141 0032 1 11 2 Tel 0120 03 6527 141 0032 1 11 2
11. c gt Jendrassik Grof Doumas 2 Bu Bc Lauff HPLC 1 10zL 4 18 28 C 4 2 8 7 18C 6 2 Bu Bc mo 200 mg dL 0 4 04 800 mg dL 0 8 0 8 B 4 zg mL 0 2 04 4 mg dL 1 8 3 2 300 zg mL 033 0 8 50 zg mL 0 7 1 1 20 zg mL 1 7 3 2
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