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1. 0 gt HbAlc 21 pl 1 252 gL 2 63 gL 37C 0 5 fos 700 nm 750 nm 700 nm 750 nm 2 21 RL 1 252 gL Ei 37C 0 570 nm 700 nm 3 HbAlc mmo1 mol HbAlc mmo1 L HbAlc mmo1 mo1 mo1 D eR Nl 1 L x1000 mo1 L HbA1c NGSP HbA1c JDS 99 HbAlc NGSP 0 0915 X IFCC mmo1 mo1 2 15 HbAlc JDS 0 980 X HbAlc NGSP 0 245 RNN gt HbAl2. 1 gmol L 0 3 3 0 mAbs lt gt HbAlc mmol mol IFCC mmo1 mo1 60 mmol mol 15 60 mol mol 9 NO gt 10 HbAlc 60 mmo1 mol CV 5 60 mmol1 mo1 SD 3 mo1 mo1 gt et BIOGBeDLS MED gt 65 130 gmol L HbAlc mmol mol IFCC 13 158 mmol mol HbAlc NGSP 3 3 16 6 HbAlc JDS 3 0 16 0 2 5 6 Y HPLC X IFCC mmo1 mo1 r 0 997 y 0 981x 0 38 3 HbAlc JCCRM411 gt 1 2 3 4 5
3. 20 mL X 3 5 mL X 3 HbAuc Sh 1000mLX 100 ml X 1 100 mL X 1 71725 2 2 x 3 47 1033 1035 1989 Koenig RJ Peterson CM Kilo C Cermami A Williamson JR Hemoglobin Alc as an indicator of the degree of glocose intolerance in diabetes Diabetes 25 3 230 2 1976 3 American Diabetes Association mplications of the United Kingdom Prospcctive Diabetes Study Position Statement Diabetes Care 22 27 31 1999 4 American Diabetes Association Tests of Glycemia in diabetes Position Statement Diabetes Care 21 77 79 1999 5 Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of 1ong term complications in insulin dependent diabetes mel1itus N Engl J Med 329 977 86 1993 6 Diabetes Control and Complications Trial Research Group The Absence of a glycemic thresho1d for the development of 1ong term complications The perspective of the diabetes control and complications trial Diabetes 45 1289 98 1996 7 Krishnamurti U Steffes MW Glycohemog1obin A primary p
4. OO 10 MS 11 kN 1 0 lt gt 1 et A NB 2 1 2 8 C 2 12
5. 25A2X00001000008 877433 2012 2 7 2009 12 6 A1c 30168000 HbAic A 2 3 4 HbAic 5 6 lt
6. PE RS 0 CS 0 lt gt 1 2 6 7 0 3 4 5 2 8C HbArc EDTA CC 1000 G 5
7. gt 1 2 25C 8 2 lt gt HbF lt gt 1 25 mg dL 20 mg dL 1000 mg dL 2000 2 Hb Hb HbAlc lt i gt 2 8 1 gt 1 2 1 26 NM 3 2 25C 8 gt
8. 1 gt 0 6 3 0 U mL lt lt 0 15 0 75 mg mL lt 3 20 U mL 2 gt oe 800 4000 U mL 10 3 7 PCE 0 008 0 03 mg mL Alc HbAltc 9 HbAic HbAlc HbAtlc IlbA1c HbAlc gt 1 HbAlc 8 N Va1 His 2
9. 8 N 3 700 nm HbAlc gt 1 HbAlc 2 570 nm HbAle gt 1 MEAN 3 15 25 5 2 8 2 80C 2
10. c NGSP 4 6 6 2 IlbA1c JDS 4 3 5 8 19 gt 1 31 61 2 21 41 3 1 lt gt 1 HbAlc 100 mAbs HbA1c 1 mo1 L 1 0 5 6 mAbs 90 be
11. redictor of the development or reversal of complications of diabetes mellitus Clin Chem 47 1157 1165 2001 8 Wieland H et al1 IFCC Reference System for Measurement of Hemoglobin Alc in Iluman Blood and the Nationa Standardization Schemes in the United States Japan and Sweden A Method Comparison Study Clin Chem 50 166 174 2004 9 Weykamp C et al The IFCC Reference Measurement System for HbAtc A 6 Year Progress Report Clin Chem 54 240 248 2008 10 37 233 241 1994 2 8 108 8559 TEL 03 6722 5710 E mail medi ho service nm medience co jp CZ77 0028 k 3 2 8 108 8559 1480
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