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Contents
1.2. 689mm
3. gt
4. AP02 03V8 YK06D01 2 8 14 83 3 1 2 3 4 1 PDT
5. 5 8 2
6. 2 3 4 5 6 1 2 4 1 4 1
7. gt gt
8. 3 3 5 4 photo bleaching 3 4 64 27 42 296
9. AST GOT ALT GPT 5 65 65 AUC 65 65
10. 1 PDT 2 1 2 1 LDL 2 PDT LDL receptor
11. lt gt 32
12. gt gt gt
13. 1 2 1 B 3B 3A 3 a i i 1 Na
14. 3 4 1 48 2 2 2
15. 22 SL130L 13B1X00119001200 1 um 1 50 1200 6400 1 05 840 5250 PRP 1 90 1520 6400 PRP165 1 96 1568 6400 1 08 864 5400 1 08 864 5400 2 01 1608 6400 160 1 92 1536 6400 1 44 1152 6400 1 04 832 5200 1 08 2 01
16. AP02 03V8 YK06D01 7 8 1 12 2
17. lt gt 3B
18. 1 160 0003 22 03 3355 0331 Carl Zeiss Meditec AG AP02 03V8 YK06D01 8 8
19. RAP 2 3 gt 4 2 1 2
20. 50 J cm 600 mW cm 83 6 mg mz 10 5
21. 25 5 15 45 29 31 5 p 0 032 CNV LDL receptor 3 classic CNV occult CNV CNV VIO 364 244 120 24 14 8
22. 8 12 59 2 3 19 3 4 796 CNV 871 365 41 996 141 16 29 82 58 2 17 2 096 38 4 496 14 1 696 15 1 796 18 2 196 40 4 696 50 5 796 31 3 696 36 4 196 16 1 896 1
23. 50 J cm 600 mW cm 83 50J cm 600 mW cm 83 1 CONTINUE ST ANDBY STANDBY R EADY 1mm 1000 m 500um PDT
24. 2 gt 1 20 10 AP
25. 1 3 1 4 7 AP02 03V8 YK06D01 4 8 2 3 1 6 1 696 1 69 4 5 2 CR 196 5
26. 6 1 10 mg kg AUC 6 mg m 40 10 mg kg 2 7
27. 3 CNV CNV AP02 03V8 YK06D01 1 8 CNV LDL receptor CNV
28. classic CNV occult CNV LDL VIP 339 LDL receptor 225 114 24 CNV classic CNV occult CNV CNV classic CNV 17 59 38 0 occult CNV 46 496 CNV 56 596 19 0
29. 1 classic CNV TAP 609 402 207 24 classic CNV 23 196 53 6 occult CNV 37 19 50 7 13 4 19 6 AP02 03V8 YK06D01 5 8 ETDRS 15 3 24 15 39 PDT 2 53 09 37 7 p lt 0 001 2
30. 8 9 1 2 4 2 3
31. 0 4 12 11 3 5 1 2 3 predominantly classic CNV minimally classic CNV TAP Occult CNV VIP VIO 24 MPS DA 4 5 6 9 Predominantly I0 3 1 8 10 8 2 6 16 2 3 5 17 2 4 9 chssic CNV n 159 n 101 n 25 n 16 n 13 19 6 2 7 28 8 3 9 24 1 44 29 3 6 6
32. CNV 1 AIGaAs 0 200mW 689 3nm 50J cm2 600mW cm lt 800 6400 m 83 0 900 90uxW 640 10nm 6 mg mX 10
33. MM 4 1 PN P N P N
34. gt 2 1 30mL 10 3mL 1 2 3 CNV 64 classic CNV classic CNV 12 classic CNV 18 89 occult CNV 14 1 1 ETDRS 12 3 0
35. gt gt AP02 03V8 YK06D01 6 8
36. 4 1 1 10 2mg kg in vitro 10 g mL 5 100g mL
37. 500 um GLD 1 000 um 2 200 um 200 um GcNV 1 CNV CNV 1 cm 50 J 600 mW cm 83
38. 15 689 3nm 50 J cmz 600 mW cm 83 1 2 1 PDT 2 1
39. 2 3 3 1 GLD greatest linear dimension 2 classic CNV occult CNV blocked fluorescence 2 4 2 6 3 GLD GLD 1
40. 17 8 15 53 39 47 596 p 0 300 30 77 596 75 096 p 0 602 1 4 CNV CNV 142 classic CNV 4 4 2 3 1 0 16 7 20 2 1
41. n 83 n 53 n 13 n 9 n 7 Minimally 9 92 2 16 4 2 7 17 0 2 4 21 23 7 chssicCNV n 202 n 77 n 34 n 41 m 41 17 8 2 7 18 3 3 8 14 9 4 4 17 5 4 5 n 104 n 40 m 21 n 22 n 17 Occult CNV 14 2 2 3 22 8 4 0 18 8 3 7 32 0 4 0 n 166 n 80 n 31 n 28 n 22 25 4 3 3 26 7 47 25 2 4 7 23 8 6 1 n 92 n 39 n 17 n 17 n 16 1 TAP 4 9DA 1 2 TAP 3 3 9DA 6 1 3 VIP 2 1 9DA 3 2 s
42. 02 03V8 YK06D01 3 8 2 3
43. 2010 07 22 8 2009 07 01 7 21500BZY00578000 31 PDT JMDN 70633000 PDT 690S 3 B 48 48
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