第28回日本呼吸器外科学会総会 委員会報告
Contents
1. i GR E Xe ui r 2 TNM 3 a 1 2 3 HA TNM 2011 5 12 Beppu 1 M SER JAE 2 TNM 3 gt lt mp 1 mE A zA 2 3 HA TNM 2011 5 12 Beppu mde SX 6 RE 2011 5 12 Beppu2. 1 2 3 4 5 6 7 8 1 9 1 2 3 4 5 JA 6 8 9 2011 5 12 Beppu 1 staging project 5 5 2004 1 1994 2 1999 3 6 6 2012 7 7 2010 gt 2 2011
3. EI m Ul 2011 5 12 Beppu 28 2004 5 1 10 2011 5 12 2004 5 20 PE E ET MES 30 2011 5 12 Beppu 5 2011 5 12 Beppu WEB AERE 32 2011 5 12 Beppu Survival Probability e AB Co e o
4. 3 follow up 2011 5 12 Beppu of 7 2010 2016 2012 A ENS 58 2011 5 12 Beppu modality PDG PET BF CIGB SURGERY GGO ratio VATS etc 59 2011 5 12 Beppu hr TI HP 1 2 3 top journal TNM 60 2011 5 12 Beppu
5. 2 1994 7408 3 2002 14925 4 1999 13310 5 2004 11663 47306 John Crowley PhD http www crab org PersonnelJohn asp 12 2011 5 12 Beppu 2011 5 12 Beppu 13 1 2 3 1 2 3 14 2011 5 12 Beppu 1 2 3 1 2 3 2011 5 12 Beppu TNM 15 1
6. 1 1994 1989 3 643 1 1998 PP ARAM 19 2011 5 12 Beppu hr TI HP 1999 1994 2 303 7 408 2 1 2002 42 555 566 2 Prognosis of 6644 resected non small cell lung cancers in Japan A Japanese lung cancer registry study Lung Cancer 2005 50 227 234 20 2011 5 12 Beppu 3 2002 Es 3 387 18 552 2 14 925 79 1 2002 2009 49 975 987 21 2011 5 12 Beppu 4 2005 1999 4 386 13 310 A Japanese Lung Cancer Registry Study Prognosis of 13 010 resected lung cancers J
7. 2011 5 12 Beppu MEE Missing 6096 s ss NENNEN m ADSQ MEN BA BEEN NENNEN xl NENNEN m AD 1994 1999 2004 N 7408 N 1330 N 11663 38 2011 5 12 Beppu clinical 100 T T 3 Iu 40 m 2 6 3 0 A AMA BE BDN _ 10 m 1 1 1 5 NM B 1 0 1994 1999 2004 N 406 N 13310 N 11663 39 2011 5 12 Beppu Hirt de F ThE 191 0 2258 lt 0 0001 T eo o Qe gx HP 1999 N 13310 2004 N 11663 Bi B dsl _ Grade gt 3 40 2011 5 12 Beppu I C e C OO gt Is gt I lt 30days B 30days ME 0 4 0 4 I p lt 0 0001 1994 1999 2004 N 7408 N 13310 N 11663 41 2011 5 12 Beppu UICC ver 6 1999 aM N 7 7 096 M 7 su 6096 0 IB Ul Na n a NM 1994 1999 A004 N 7408 N 13310 N 11663
8. 2004 B 2009 C 1 1 2 2 p PS UICC TNM 1997 N M 1 c stage 6 4 767 UICC TNM 1997 2011 5 12 Beppu Japanese Lung Cancer Registry Study First Prospective Enrollment of a Large Number of Surgical and Nonsurgical Cases in 2002 NSCLC nz12993 SCLC 1323 d RR T l B JUS pon Fi L w E UL Wika E 1 LL 8 L s A IB 8 IA xi IB 2l _ IIB T I Da 0 L E 3 5 1 B 3 5 Years Years Independent prognostic factor C stage gender histology treatment PS Sawabata N et al J Thorac Oncol 2010 5 25 2011 5 12 Beppu 2010 2004 5 253 11663 JTO 2011 in press 26 2011 5 12 Beppu 5 2004 27 2011 5 12 Beppu 5 HQ ESI A
9. 2011 5 12 Beppu lt 0 0001 UICC ver 6 1999 MEM EM 8096 T 70 ma B iiA Ul B B 405 E 1994 1999 2004 N 7408 N 13310 N 11663 2011 5 12 Beppu p lt 0 0001 I C stage 10 1996 DYOR c stage verb A 11 5 50 1 HA 47 8 IIB 40 4 34 6 21 6 IV 19 9 1999 YoS 6 11 0 60 1 93 0 43 6 38 0 33 6 21 0 2004 SRY 9 82 0 63 4 09 4 48 6 43 3 41 6 29 1 2011 5 12 Beppu 44 P stage 10 1996 Y oO Co p stage verb A 19 2 IB 60 1 HA 58 6 IIB 42 2 21 4 IIIB 20 2 IV 19 3 1999 SYSR U 83 3 06 4 60 1 4 1 2 32 8 30 4 23 2 2004 YS 6 65 9 69 3 60 9 91 1 41 0 36 7 21 8 2011 5 12 45 ORIGINAL ARTICLE Japanese Lung Cancer Registry Study of 11 663 Surgical Cases in 2004 n and Prognosis Changes Over Decade Variyashi MI PhD Ersuo Miyaoka PAD Hisao Asamura MD Foichi Nakanishi MD PhD Kenji Eguchi MD PhD Masaki Mori MD PhD f Hiroagk Nomor MD PAD Foshiaka MD
10. Survival Function 69 6 2004 62 0 1999 52 3 1994 47 8 1989 survival Probability C stage specific prognosis in 2004 Survival Function 9 8 6 4 3 2 1 0 0 0 1 2 years IIIA IIIB UICC ver 7 2009 Tota c stage IB V n 11663 0295 2339 019 040 1216 90 290 h 04 0 20 1 1 0 9 0 10 4 0 1 2 2 5YSRW 09 6 82 0 60 94 5 40 4 42 40 314 34 2011 5 12 Survival Probability P stage specific prognosis in 2004 UICC ver 7 2009 Survival Function Total Es p stage i m IB _ mA s me lA IIIB if 1 2 3 4 IN years n 11663 4918 290 94 040 1804 106 434 42 21 9 0 19 9 0 9 3 1 5YSRW 09 6 00 0 13 9 01 6 49 0 40 9 21 8 21 9 35 2011 5 12 Beppu NN NENNEN os BM 90s x j NEM 80s AM S 2705 o 8M 2605 os D E TIR x RM TM ox NM 20 lt j B e 1994 1999 2004 N 7408 N 13310 N 11663 x 2011 5 12 Beppu 25 Xx EE BHL m B un C 1994 1999 2004 N 408 N 13310 N 11663 m
11. PhD Meinasin Okumura MD and Kohei Yakor MD PhD FT for the Japanese Joint Committee jor Lung Cancer Revisiratromn journal of Thorcc Oncology Volume Number une 7011 46 2011 5 12 Beppu Prevalence of CT in Pts with LC Lung Ca found Lung Ca found by routine care incidentally by CT m a Aggressive cohort indolent cohort rapid growth i e slow growth good early metastases prognosis T stage Detterbeck FC JTO 6 417 2011 47 2011 5 12 Beppu Stage distribution and PET A Change in Stage IV NSCLC B rends in NSCLC California Ca Registry US National Cancer Database 50 V 42 Community Hosp 100 649 year Mt gt 40 Community Hosp gt 650 year zl 5 III E 36 tom 5 34 1 National Cancer Database O 1998 2006 G o 32 813 302 NSCLC patients 30 1 1998 2000 2002 2004 2006 Year 1994 1905 100 1007 1908 1000 2000 2001 2002 2003 2004 Year Detterbeck FC JTO 6 417 2011 48 2011 5 12 Beppu CT 7 http www nikkeibp co p archives 418 418825 html TODA a E A 100 TUA 252A Ed s H HA Gerard F et al Health Affairs 2005 24 903 81 4 2011 5 12 Bepp
12. Thorac Oncol 2008 3 46 52 2 Pulmonary resection in patients aged 80 years or over with clinical stage I non small cell lung cancer Prognostic factors for overall survival and risk factors for postoperative complications J Thorac Oncol 2009 4 1247 1253 3 Visceral pleura invasion impact on non small cell lung cancer patient survival Its implications for the forthcoming T NM staging based on a large scale nation wide database J Thorac Oncol 2009 4 959 963 4 Improvements in surgical results for lung cancer from 1989 to 1999 in Japan J Thorac Oncol 2009 4 1364 1369 9 Survival Differences by Gender for Resected Non Small Cell Lung Cancer A Retrospective Analysis of 12 509 Cases in a Japanese Lung Cancer Registry Study J Thorac Oncol 2010 5 1594 601 22 2011 5 12 Beppu 2005 H H H H NH 5 2008 2009 3 2002 1 Japanese Lung Cancer Registry study First prospective enrollment of a large number of surgical and nonsurgical cases in 2002 J horac Oncol 2010 2 1369 1375 23 2011 5 12 Beppu 2002 3 18 552 14 925 79 10 183 55 2002
13. 5 12 Beppu gt St e 260 SERES CIAO 240 ze zc 180 DEM 160 Ns E _ 5 CEALL b a 120 i 100 all 0I T eene Ni rf CREE 2E ch ai 4 B c ET bom d 2 PII s PPP ISI zu pum T ag 0 dm at 40 50 50 2 7 I 17 http www mhlw gojp toukei saikin hw jinkou geppo nengai05 kekka3 html 10 I aa X 2 7 WW I a ds 23 7 p HBH F HBH F 4 Ert p HP http www mhlw go jp toukei saikin hw jinkou ebpp4P eC 089DDMa3 html Bs g 1975 B C _ NSCLC SCLC MI A um T B tJ au _ uu at L E E d 7 L S Is IB 8 I T IA jp IE _ MA 1 T 3 IB MiB a X MA 3 _ IB UI I Du s L e 3 5 0 1 e 3 u g Years Years Sawabata N et al J Thorac Oncol 2010 5 5 2011 5 12 Beppu UICC TNM ver 7 2009 M 6th edition TNM Stage A A c 2 O 1 lt 2 1 gt 2 3 T2 lt 5cm IA IIB T2 55 7cm IA B lB IIB o T4 extension 1118 IIIB IV IV MB IV MB IV _ M1
14. 5 2 USB gt USB Windows 55 2011 5 12 Beppu maf 00000001 K001 00000003 K002 0000004 K003 2 000005 K004 000006 K005 0007 K006 jH rom 17 7 ID 1 90 o 1 BEN e Oz OUUU 00000062 B A x O O XE a Ma ee Bj zz Ed EFA Xu EZ mm 2010 10 29 AE ESSN Bin EDESA 26 62 gt ID demo PW demo rm x 56 2011 5 12 Beppu Geography Histology TNM E FGR gene mutation etC
15. ipsilateral lung 00 uu T4 pleural effusion M1 contralateral lung T2 gt 7cm IIB IB HB T4 same lobe nodule IIB 118 MI O staging project 7 2011 5 12 Beppu Chairman International Staging Committee of the IASLC Ramon M D Hospital Universitari Mutua Terrassa Spain 8 2011 5 12 Beppu Next Chairman International Staging Committee of the IASLC Hisao Asamura M D okyo National Cancer Center Japan 9 2011 5 12 Beppu TNM 7728 Ver 8 2016 Staging Droject time table e 2009 2010 prospective data correction e 2011 2012 date follow up e 2013 data analysis e 2014 recommendation to UICC AJCC e 2015 publication in J Thorac Oncol e 2016 publication by UICC AJCC 10 2011 5 12 Beppu Staging Droject data base 1 7 date base 2 IASLC 3 2000 2009 retrospective data 11 2011 5 12 Beppu hr TI HP TNM Ver 8 2016
16. u 6 2012 2011 5 12 Beppu 53 6 2012 82 __ i 54 OH MA 0 TIN lt _ _ H XH N 2011 5 12 Beppu 2012 Web Z
17. u PET 300 290 200 150 100 90 2004 2005 2006 2007 2008 INOVATION 24 53 54 2009 50 2011 5 12 Beppu 0 alaa The results of completely resected lung cancer involving neighboring structures in Japan T3 Prognosis of patients with resected NSCLC invading neighboring organs T4 L EOS Postoperative survival of patients with IIIA N2 non small cell lung cancer in Japanese Lung Cancer Registry Study Prognostic Value of Intraoperative Pleural Lavage Cytology for Lung Cancer 1 2011 5 12 Beppu 2004 e 3 2010 2011 JTO in press 2010 11 1 50 fies EE Se zs B COURIR 2 52 2011 5 12 Bepp
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