別紙2（PDF：437KB）
Contents
1. 1 http www japan lsd mhlw jp lsd_doctors gaucher htm12. 3 1 NNE TL 1 1 I 37 4 27 9 34 7
3. ID 10 ID
4. 1 6 1 2 xTAG V3 CYP2D6 kit v31 03 5545 7440 RUO Luminex 40 010 11B1X10017000005 100 200 03 5545 7440
5. 1 6 1 VP AR106K63 219ABBZX00032 I 19mm 0 6 mm 21600BZY00074000 PSV 1
6. ID 5 3 xTAG CYP2D6 kit v3 RUO CYP2D6 CYP2D6 xTAG CYP2D6 kit v3 RUO EDTA DNA DNA PCR 9 24 ng 1800 ng DNA PCR A PCRB 2 PCR 2 PCR PCR A PCR B dNTP PCR
7. 5 698 20 1 100mg1 76 925 90 510 00 54 EE 0 566 33 79 286 20 66 928 10 4 40 2 3 2 6 4 2 7 3 2014 8 FE 27 5 2 0 27 4 17 5
8. 330 000 1 150 RON 100mg CYP2D6 Intermediate metabolizer IM Extensive metabolizer EM 20 2 CYP2D6 xTAG CYP2D6 kit v3 RUO 2 1 Extensive metaboliz
9. a a 1 2 1 6 9 PP x120 20 3 NE WR DD RT RD 4p ES 2 0 UE
10. ASPE 5 xTAG Luminex 1007200 2 1 CYP2D6 QOL a 1 xTAG CYP2D6 kit v3 RUO CYP2D6 2 xTAG CYP2D6 kit v3 RUO CYP2D6
11. xTAG CYP2D6 v3 RUO 3 RI SU KH KS was 0 1 i 2 2 SS gt
12. SAP Shrimp Alkaline Phosphatase SAP EXO PCR SAP EXO ASPE Allele Specific Primer Extension ASPE Streptavidin R Phycoerythrin SA PE Luminex 1007200 4 xTAG CYP2D6 kit v3 RUO CYP2D6 Intermediate metabo izer Extensive metabolizer EM 1 100ng 1 2 U1tra Rapid Metabolizer URM Pocr Metabolizer PM 5
13. CYP2D6 6 CYP2D6 9
14. TVD US BU IVD 15 05 5 399 100mg 100mg 1 Uy CYP2D6 Extensive Metabolizer Intermediate Metabolizer 1 100mg 1 2 j f 52 908 20 3 476 00 20 3 4 843 50 6 8 a FF
15. 5 CYP2D6 CYP2D6 xTAG CYP2D6 kit v3 RUO kit Luminex 1007200 kit xTAG PCR PCR ASPE ASPE 5 xTAG
16. er EM 1 Intermediat e metabolizer IM 2 5 EM IM 541 061 35 038 15 607 591 706 xTAG CYP2D6 v3 RUO Mid 1 CYP2D6 2 1
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