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TSKgel G8 HSi

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1. c e e S 4 elt N e t e zm Bf EO JAC AY E En A e e e
2. G8 HSi 3 5 6 1 4 15 C 7 8 4 MPa 12 HLC 723G8 Format 610 amp ox om mio Eo S somanroo X XN gt S 28 oiga D c a o o NONE L4 Ss oe 0 9 z oz lt u oor x On om e 6 6 e eters a o 2 28 8 3 ES eg gs or LE gt N JO lt o OrRonamn
3. e e 15 NEU DIT emen ooo TA a i
4. HbA L A REH HbA s A ERODED HbA OWE YT LA 1 3 s A LA Es Aj amp LA s A s A 1 0 2 1 1 3
5. s A n 10 Low Medium High Mean 5 17 7 47 9 76 SD 0 05 0 05 0 05 CV 96 0 97 0 67 0 51 2 n 10 2 1 1 10 EDO s A Low High Mean 5 21 9 75 SD 0 03 0 07 CV 0 58 0 72 16 10 g L mg dL mg dL g L X 100 1 10 g L 0 25 g L 0 20 g L RMR g L Hb Hb 96 0 05 0 10 0 15 0 20 0 25 g L Hb
6. 0021498 TSKgel G8 HSi 14 Standard Analysis Mode HLC 723G8 4 m HbA1c J 0018198 HbA1c 0021974 G8 HSi 1 S 0021800 G8 HSi 2 S 0021801 G8 HSi 3 S 0021802 HSi D 0018431 HSi LL 0019550 6 4 15 7 s A 8 HPLC 1 0 6 3 GS G8 HSi 1 S G8 HSi 2 He S G8 RENE HSi 3 S HbF X s A Total A 9 TSKgel
7. PPPPPPPPPFFPPTPPPPPPPYYYYP eee ere eee reer eer ere eee eee eee eee ee eee eee ONOOR OD 10 O o 11 rs 12 eee ere eee eee eee eee eee eee eee 13 osas 14 dar ds ss aaa 15 A O O 16 ere eee eee eer errr ere er reer eer rere eee rere errs 17 ee 2012 4 2009 8 1 HLC 723G8 HLC 723G8 GHb BHO N HbA HbA 2 1 N
8. 0 10 0 15 0 20 g L 0 00 0 05 10 2 019 g L 0 20 g L 2 180 WILY 2 Y iE 0 50 g L 3 HbF 17 EDTA NaF 25 24 4 14 Safety Precautions To help protect you and or your property from potential damage and ensure personal safety please read this IFU thoroughly before using the product Notational Convention Notation Explanation Indicates a hazard with a low level of risk which if not avoided could result ZNCAUTION in minor or moderate injury ZN CAUTION E Use only in well ventilated areas In case of insufficient ventilation flammable and toxic solvents can cause fire explosion or poisoning W First Aid
9. gt 2 2 3 4 5 2 6 10 HLC 723G8 11 o 2 HLC 723G8 G8 HE HSI 1 2 3 S HSi VENAE Is H9 3 4 A peor
10. 2 2 Total Area s Ax 90 324 50 9 2 652 54 9 7 939 78 9 8 1199 05 9 8 1552 53 9 9 1833 12 9 9 2104 36 9 9 2321 57 10 0 2610 74 10 0 2858 85 10 1 s A g A 96 0 10 2 8 1 9 4 4 4 3 102 3 2 8 6 2 6 4 96 9 3 7 8 2 8 3 98 8 4 6 10 1 10 2 99 0 5 5 11 9 12 1 98 3 6 4 13 6 13 9 97 8 7 3 15 4 15 6 98 7 8 2 17 2 17 4 98 9 9 1 19 0 19 3 98 4 10 0 20 4 3 HLC 723G8 HLC 723G7 HLC 723G8 HLC 723GHbV s A 90 LOT 3 AINS EO HbA JCCLS CRM 004a JCCLS CRM 004a JDSLOT 2 HLC 723G8 HLC 723G7 S Ayo 0 989x 0 057 1 1 y 14 0 8D 2 O1H 2 0 4 0 6 0 8 0 12 0 14 0 HLC 723G7 2 0 723GHbV HLC 723G8 HLC S Ayo 89 2L 0 1H HLC 723GHbV 15 1 n 10 3
11. Les instructions d utilisation sont disponibles en plusieurs langues sur notre site web www tosohbioscience eu dans la rubrique Service amp Support Vous pouvez obtenir un exemplaire papier par fax au n 32 13 66 47 49 ou par e mail l adresse info raqa eu tosoh com Version Actuelle G8S 01010 A Haszn lati utas t s t bb nyelven el rhet websz jtunkon www tosohbioscience eu a Service amp Support Szolg ltat s s T mogat s szekci alatt Nyomtatott v ltozat ig nyelhet faxon a 32 13 66 47 49 es telefonsz mon vagy e mailben info raqa eu tosoh com Aktu lis V ltozat G8S 01010 Istruzioni per l Uso in diverse lingue sono disponibili sul nostro sito web www tosohbioscience eu alla sezione Service amp Support Versione cartacea pu essere richiesta via fax al 32 13 66 47 49 o via e mail a info raqa eu tosoh com Versione Attuale G8S 01010 Naudojimo instrukcijas vairiomis kalbomis galite rasti m s tinklalapio www tosohbioscience eu skyriuje Service amp Support Popierine versij galite gauti faksu 32 13 66 47 49 arba el pa tu info raqa eu tosoh com Naujausia Versija G8S 01010 Symbols on the product labels CE European Conformity Catalogue number Part number Use by date Zo ot column ON For specified column lot only Manufacturer In vitro diagnostic medical device LOT Batch code Lot nu
12. Confirm that the following two documents are included in the package Instructions For Use 1 copy Glyco column inspection report 1 copy 3 Warnings and Precautions 1 This product is for in vitro diagnostic use only 2 This product is intended for use on the Tosoh Automated Glycohemoglobin Analyzer HLC 723G8 Standard Analysis Mode only 4 Content Catalogue No Description Package content 0021498 TSKgel G8 HSi 1 piece Packed resin Cation exchange resin Assay mode Standard Analysis Mode Applicable analyzers Tosoh Automated Glycohemoglobin Analyzer HLC 723G8 5 Part Names The names of the various parts comprising the TSKgel G8 HSi are shown eH He Name plate E End fitting End plug below CE IVD marks lt Illustration of Column gt 6 Related Components Catalogue No Hemoglobin A1c Calibrator Set 0018767 Hemoglobin A1c Control Set 0021974 G8 Elution Buffer HSi No 1 S 0021800 G8 Elution Buffer HSi No 2 S 0021801 G8 Elution Buffer HSi No 3 S 0021802 HSi Hemolysis amp Wash Solution L 0018431 HSi Hemolysis amp Wash Solution LL 0019550 7 Storage Store at 4 to 15 C in a cool dark location 8 Specimens Whole blood samples 9 Assay Principle The HLC 723G8 is based on the High Performance Liquid Chromatography HPLC principle Cation exchange columns employ the differences in ionic interactions between hemoglobin components to separate them into
13. No special preparation is necessary A venous blood sample is collected aseptically The blood samples in primary tubes which contain EDTA NaF Heparin or Citric acid may be stored at 25 C for 24 hours prior to analysis or at 4 for 14 days TOSOH wamax 3 8 2 105 8623 TEL 03 5427 5181 FAX 03 5427 5220 MI TOSOH CORPORATION BIOSCIENCE DIVISION Shiba Koen First Bldg 3 8 2 Shiba Minato ku Tokyo 105 8623 Japan Phone 81 3 5427 5181 Fax 81 3 5427 5220 TOSOH EUROPE N V Transportstraat 4 B 3980 Tessenderlo Belgium Phone 32 13 66 88 30 Fax 32 13 66 47 49 This manual may not be reprinted or copied in whole or in part without written consent of Tosoh Corporation The contents of the manual are subject to change without notice HLC TSKgel HLC is the registered trademark of Tosoh Corporation in Japan TSKgel is the registered trademark of Tosoh Corporation in Japan United States China etc Printed in Japan T1206 2
14. is a general term for complexes where the whole blood glucose is non enzymatically bound to the or chains of human hemoglobin Within these complexes HbA which is a complex of glucose and the N terminus of the chain is the most quantitatively prevalent HbA is non enzymatically synthesized in two steps Step 1 The glucose aldehyde group reacts with the free amino group on the valine comprising the N terminus of the chain to form the Schiff base labile HbA L A Step 2 Stable ketoamine stable HbA s A is then formed by a reaction known as the amadori rearrangement Due to the fact that L A the intermediate product of this reaction changes rapidly in response to the changes in whole blood glucose concentrations s A is now generally used to measure HbA It provides the best indication of average glucose levels over the most recent 1 to 3 month period because it does not fluctuate in response to physiological factors In the past it was difficult to achieve quick separation of L A and s A on a column therefore sample pretreatment to remove L A was necessary before assaying s A The HLC 723G8 features quick separation of L A and s A on the column 1 0 min with no need for sample treatment when assaying s A 2 Prior to Use Inspect the column package and package components for any signs of damage prior to use If any damages are visible contact your local Tosoh sales representative
15. oc ec j gt 6 z okooooo O o w a i at e pp topp o e Ss T T Eaka peia o Once 880 a occz gt a a Sw Se I sz ss or oc e so care lt lt 0 lt lt 32 8 ccokcaags wx e Sh 2888558823 N 2 G6 6 lt lt gt de 2 e 9 oooc oss Y ENANS y a o Noa bd 13 2 S o 0 z 23 gsesssees mm FEST 8 22 243 eo Nro o COooooooo LI ox e gt S ASS zx oo U o w lt EM Mu o e Soc Gaur occ 588 a 0 a w oo lt 2 S 3 E lt o 22 I 9 oaz co 2 a z o o Oo 21 14 Measurement Values Measurement values indicate the percentage of each peak in relation to the Total Area excluding the front peak FP Note the minimum unit of measurement displayed is 0 1 15 Evaluation of Results Quality Control In order to monitor and evaluate the precision and analytical performance it is recommended that control samples should be run daily If one or more control sample value s is out of the acceptable range it is necessary to investigate the validity of the calibration curve before reporting patient results Standard laboratory procedures should be followed in accordance t
16. G8 HSi G8 HSi HbA1c HbA1c HSi HLC 723G8 1 1 STATUS 1 2
17. a total of six factions in a span of 1 0 min A step gradient elution is used to separate HbF s A and Total A with three types of G8 Elution Buffer HSi G8 Elution Buffer HSi No 1 2 and 3 S of different salt concentrations 10 Installation Be sure to read the IFU included with the TSKgel G8 HSi G8 Elution Buffer HSi Hemoglobin A1c Calibrator Set Hemoglobin A1c Control Set and HSi Hemolysis amp Wash Solution as well as the HLC 723G8 Operator s Manual 1 Take a column from its box and remove the end plugs from both ends Keep the plugs in a safe place as they will be needed when the column is stored 2 Confirm that analyzer system eluent delivery has been terminated STAND BY is displayed on the Main screen No 1 screen before opening the column oven to disconnect the tubing Then remove the used column 3 Press the arrow key at the bottom right of the Main screen No 1 screen to show the Main screen No 2 screen Press the pump key on the Main Screen No 2 screen to start the pump and check the eluent flows through the tube disconnected from the column Then stop the pump by pressing the pump key again Take special care that eluent coming from the tube does not spill onto the analyzer unit by preparing wiping paper beforehand 4 Confirm the correct eluent flow direction referring to arrow displayed on the column name plate and connect a tube to the column inlet side Start the pump and check that the elue
18. HaLuma ye6caMT www tosohbioscience eu B pasnena Momo n nonapexka Service amp Support XaDTMeHO konne Moxe na 69e nonyueHo Ha fax 32 13 66 47 49 unn e mail info raqa eu Qtosoh com Akryanua Bepcua G8S 01010 v Lietosanas instrukcijas dazadas valodas ir pieejamas m su interneta vietn www tosohbioscience eu sada Service amp Support Apkalpo ana un Atbalsts Druk tu versiju iesp jams sa emt pa faksu 32 13 66 47 49 vai e pastu info raqa eu tosoh com Aktu l Versija G8S 01010 N vod k pou it v r zn ch jazyc ch je dostupn na na ich webov ch str nk ch www tosohbioscience eu v sekci Service amp Support Tist nou verzi m ete obdr et faxem slo 32 13 66 47 49 nebo e mailem info raqa eu tosoh com Aktu ln Verze G8S 01010 Flersprogede brugsanvisninger findes p vores hjemmeside www tosohbioscience eu under Service amp Support sektionen Trykte brugsanvisninger kan rekvireres pr fax 32 13 66 47 49 eller e mail info rada eu tosoh com Nuveerende Version G8S 01010 a Instrukcja Uzytkowania w r znych jezykach jest dostepna na naszej stronie internetowej www tosohbioscience eu w zak adce Service amp Support Serwis i Wsparcie O wersj papierow mo na pyta pod nr faksu 32 13 66 47 49 lub e mailem info raqa eu tosoh com Aktualna Wersja G8S 01010 Bedienungsanleitungen in verschiedenen Sprachen sind auf unserer Webseite ww
19. Rev DC011J011 DC011E011 HLC 723G8 Tosoh Automated Glycohemoglobin Analyzer HLC 723G8 Instructions For Use TSKgel G8 HSi CE o TOSOH CORPORATION TOSOH
20. Skin exposure Wash exposed area with plenty of soap and water Eye exposure Open eyes as wide as possible and wash with clean water for at least 15 minutes Immediately call for medical attention Ingestion Please wash mouth with excess water and immediately call for medical attention lll Do not spill solvents Spillage and leakage can cause fire electric shock poisoning injury and corrosion Wear appropriate protective gear when cleaning up a spill lll Wear eye protection and protective gloves Organic solvents and acids are harmful and should not come in direct contact with the skin lll Handle package with care Inappropriate handling may cause rupturing and or spattering of the product H Only use this product as intended This product is intended for in vitro diagnostic use for the measurement of HbA in blood Specimens H Proper disposal Dispose in accordance with local laws and regulations NOTE Keep this IFU with the product for future reference EU rev G8S 01010 Esponetickn norpeGurenw Evrop t z kaznici Europ iske kunder Europ ische Kunden European customers Eupwrra o mgAdrec Clientes europeos Euroopa kliendid Consommateurs europ ens Eur pai gyfelek Clienti europei Europos klientai Eiropas klienti Klienci europejscy Clientes europeus Clientii europeni Evropski kupci Eur pski z kaznici Europeiska kunder Uncrpyxuun sa ynorpe6a Ha pasnnunn esnyn ca Ha PasnorloKeHMe Ha
21. io S A 96 s Aic 96 96 0 10 2 7 1 9 4 7 4 7 100 0 2 8 6 5 6 7 97 0 3 7 8 4 8 5 98 8 4 6 10 2 10 3 99 0 5 5 11 9 12 2 97 5 6 4 13 6 13 9 97 8 7 3 15 3 15 5 98 7 8 2 17 0 17 3 98 3 9 1 18 8 19 0 98 9 10 0 20 1 3 Correlation The correlation between the s A values for the HLC 723G8 and HLC 723G7 analyzers and for the HLC 723G8 and HLC 723GHbV A1c2 2 analyzers are shown in the graph below These methods are certified by the National Glycohemoglobin Standardization Program NGSP The correlation between the s A 96 for HLC 723G8 and HLC 723G7 analyzers S A 111 gt gt gt gt 551 12 0 10 0 HLC 723G8 so o HLC 723G7 The correlation between the s A 96 for HLC 723G8 and HLC 723GHbV A1c2 2 analyzers s A HLC 723G8 20 40 6 0 8 0 10 0 120 140 HLC 723GHbV 18 Precision 1 Intra assay n 10 The intra assay precision n 10 factors of the s A for three types of control samples are shown below Low Medium High Mean 5 47 7 68 9 90 SD 0 05 0 06 0 00 CV 0 91 0 78 0 00 2 Inter assay n 10 The inter assay precision n 10 factors measured once a day for a 10 day period of the s A 96 for two types of control samples are shown below Low High Mean 5 52 9 88 SD 0 04 0 06 CV 96 0 72 0 61 19 Interferences A substance is considered to interfere when the
22. mber SN Serial number Column number Authorized representative in the European Community Consult instructions for use Temperature limitation NET Net volume after reconstitution for lyophilized material CONTENTS 1 Introduction DE 3 6 723 Prior to Use once sh 1 F 3 Warnings and Precautions DE 17 4 Content IDEE 17 5 Part Names DEEP 18 6 Related Components EE 18 T Storage IEEE 18 8 Specimens DEED 18 9 Assay Principle DP 18 10 Installation EE 1 9 11 E Assay Procedures danna anar cocoa rr 20 12 Precautions for Use E 20 13 Reference Data DP 21 14 Measurement Values E 22 15 Evaluation of Results n 22 16 Expected Values eee eee cece rr nora 22 17 Performance Characteristics 66 22 18 Precision DE 25 19 Interferences nM 26 20 Specimen Collection and Handling veseve 28 Revised in April 2012 1 Introduction The TSKgel G8 HSi is designed exclusively for use with the Tosoh Automated Glycohemoglobin Analyzer HLC 723G8 referred to as HLC 723G8 in the IFU which is based on the principle of High Performance Liquid Chromatography assay It is not designed for and should never be used with any other type of system The TSKgel G8 HSi is intended for in vitro diagnostic use for the measurement of hemoglobin A HbA in blood specimens Hemoglobin A measurements are used in the clinical management of diabetes to assess the long term efficacy of diabetic control Glycohemoglobin GHb
23. nt flows through the column Then stop the pump and connect the tube to the outlet side of the column 5 Press the pump key again to start the pump Check that the pressure level rises quickly and that there is no leakage from the tube connections 6 Press the MAINTE key and then the REAGENT CHANGE key Press the COL RESET key to reset the column counter 11 Assay Procedures Refer to the HLC 723G8 Operator s Manual for detailed instructions 12 Precautions for Use 1 Carefully read the instructions contained in this IFU and related Instructions For Use provided with HLC 723G8 G8 Elution Buffer HSi Hemoglobin A1c Calibrator Set Hemoglobin A1c Control Set and HSi Hemolysis 8 Wash Solution 2 The used column has been in contact with blood sample Wear protective clothin lasses glove mask etc and take sufficient care to prevent potential infection during installation and handling 3 The TSKgel G8 HSi is designed exclusively for use in combination with the HLC 723G8 analyzer system G8 Elution Buffer HSi and HSi Hemolysis amp Wash Solution indicated below never in any other combination Tosoh Automated Glycohemoglobin Analyzer HLC 723G8 G8 Elution Buffer HSi No 1 2 and 3 S HSi Hemolysis amp Wash Solution L LL 4 When replacing column be sure to assay dummy samples to check the chromatogram results 5 Always use the TSKgel G8 HSi in combination with the G8 Elution Buffer HSi of the identical lot numbe
24. o the strictest regulatory agency under which the laboratory operates 16 Expected Values Reference ranges non diabetic HbA S A 4 0 6 0 mean 5 0 96 SD 0 5 96 Ref American Diabetes Association Standards of medical care for patients with diabetes mellitus Diabetes Care 2000 23 Suppl 1 S32 42 The values referred to within this document have been determined with a NGSP certified method It is known that the relationship between HbA results from the NGSP network 96 and the IFCC network mmol mol is expressed by using the following equation See http www ifcchba1c net IFCC 08 asp NGSP 0 09148 X IFCC 2 152 17 Performance Characteristics 1 Linearity Dilution The tests were performed with Hemoglobin A1c Control diluted with various percentage factors to determine the effect on the s A value Linearity was Observed for the Total Area in the 500 to 2700 range and measurements in the range of 700 to 2500 are recommended to give more reliable results Total Area S A c 96 324 50 9 4 652 54 9 9 939 78 9 9 1199 05 9 9 1552 53 10 0 1833 12 10 0 2104 36 10 1 2321 57 10 1 2610 74 10 1 2858 85 10 2 2 Recovery Linearity The table below shows the recovery ratios for two types of samples mixed in different percentage factors High s A Low s A Measurement Theoretical Recovery sample sample value value ratio rat
25. r The column lot number is indicated by a single uppercase alphabetical character A B etc on the label of column box The Elution Buffer label displays an alphabetic character corresponding to column lot number as shown below Note that the G8 Elution Buffer HSi No 3 is compatible with all lots 6 Care must be taken to ensure that the solutions are delivered only in the direction indicated by the arrow on the column label 7 In cases in which the column is not used for more than one week remove the column from the analyzer unit reattach its end plugs to protect it from drying out and store in a cool dark place between 4 and 15 C 8 Please handle the column with care Do not drop or shake the column 9 If the pressure is more than 4 MPa higher than the pressure which is indicated on the column inspection report replace the filter If the pressure still does not drop please contact your local representative 10 For safe waste disposal it is recommended that each laboratory complies with established laboratory procedures and local state and federal regulations 13 Reference Data from the HLC 723G8 Assay Examples Format 100 Control 15 oo a n lt Sooocacon x gt n BS US ANTIDO oo D AA 7o o oucosr s 0 e gt PENON DT w o e co e e 3 S 0 z gz uwooooooox m e X QOO mM 2 e xc e T o o o o o E S NES 6 I T o Dj
26. recovery of a known specimen falls outside a 10 acceptability range Concentrations of interfering substances in this IFU are in units of g L Conversion to units of mg dL may be made using the following equation mg dL g L X 100 1 No effect was observed below 10 g L for glucose 0 25 g L for sodium cyanate and 0 20 g L for acetaldehyde Glucose Effect of labile Ac Hb Control concentration g L Sodium cyanate Effect of carbamyl Hb Control concentration g L Acetaldehyde Effect of aldehyde Hb Control concentration g L 2 No effect was observed for the following agents up to the concentrations indicated in the table Free bilirubin to 0 19 g L Conjugated bilirubin to 0 20 g L Chyle to 2 130 Formazine turbidity Aspirin to 0 50 g L 3 The presence of HbD HbS HbC and HbE does interfere with the assay High HbF and specific types of hemoglobin variants may interfere with the assay 4 In the presence of HbE a shoulder or small peak may be observed behind S A peak 5 Low concentrations of hemoglobin may cause the Total Area of the chromatogram to be lt 500 6 A reduced concentration of HbA may be observed in patients due to limited life span of red blood cells interpret clinical results with caution 7 Hemolysis does not interfere with HbA assay results 20 Specimen Collection and Handling A whole blood sample is required for the assay
27. rsion G8S 01010 Ve jezi na navodila za uporabo so na voljo na na i spletni strani www tosohbioscience eu v razdelku Service amp Support Servis in podpora V papirni obliki jih lahko prejmete po faksu 32 13 66 47 49 ali elektronski po ti info raqa eu tosoh com Aktualna Razli ica G8S 01010 Las instrucciones de uso est n disponibles en diferentes idiomas en nuestra p gina web www tosohbioscience eu en la secci n de Service amp Support Servicio y Soporte Tambi n podemos enviarle una versi n impresa a trav s del fax 32 13 66 47 49 o por correo electr nico info raga eu tosoh com Versi n Real G8S 01010 N vod na pou itie vo viacer ch jazykoch je dostupn na na ej web str nke www tosohbioscience eu v sekcii Service amp Support Vytla en verziu mo no z ska faxom 32 13 66 47 49 alebo cez e mail info raqa eu tosoh com Aktu lna Verzia G8S 01010 Eri keeltes kasutusjuhendid on saadaval meie veebilehel www tosohbioscience_eu alajaotuses Service amp Support Paberkandjal versiooni saab tellida faksinumbril 32 13 66 47 49 v i e posti teel info raqa eu tosoh com Kehtiv Versioon G8S 01010 Bruksanvisning p flera spr k finns att tillg p v r webbplats www tosohbioscience eu under rubriken Service amp Support En pappersversion kan erh llas per fax 32 13 66 47 49 eller e post info raqa eu tosoh com Aktuell Version G8S 01010
28. t 8 scceewer 8 B c Sonn 2 8 o ro gt roo o o e w oo lt lt La LEE lt o a 2 20 oos gare o d o o Format 610 oo T Ed nr mM X Qn c0O1D nu Ro o Go6 N XN S 28 5 Esrkcccggr t O 7 amp Se 8 88K 27S amp 5 lt o 0 z az T o a lt w u x r 2239225 amp s wo s e s s s so ac Se 3 C Ocococoo B Di eS 2 z g NO O lt BL owoone s 2 o Fd s Sooo ecE 8 8 o Sacre Ss 2 8 o 5823 T ow gt ro 3 o o eco2z o w oo lt lt E SO se oe od dc a go ocos Xa c d t o 13 FP Total Area 0 1 14 1 HbA1lc Level 2 s A Total Area 500 2700 700 2500
29. w tosohbioscience eu Im Kapitel Service amp Support erh ltlich Ein Papierexemplar erhalten Sie auf schriftliche Anfrage an Faxnummer 32 13 66 47 49 oder per E Mail an info rada eu tosoh com Aktuelle Version G8S 01010 As instruc es de utilizacao encontram se disponiveis em diversos idiomas no nosso sitio www tosohbioscience eu na secg o Service amp Support Servicos e Assist ncia Pode ainda obter uma vers o em papel atrav s do fax 32 13 66 47 49 ou do email info raqa eu tosoh com Vers o Actual G8S 01010 Oa pps re ric O6nYigc xprjanc os ToAAEc YAWOOES OTN BIADIKTUAK rorroGzo a pa www tosohbioscience eu onv ev rta Service amp Support Mrrope te va AGBete TnV EviuTn HOP urroB AAovrac a tnon p ow pag otov api p 32 13 66 47 49 A p cw AEKTDOVIKOU TOXUODPOHEIOU info rada eu tosoh com Tp youca Exdoon G8S 01010 Instructiuni de utilizare in diverse limbi sunt disponibile pe site ul nostru www tosohbioscience eu la sectiunea Service amp Support Service si asistent tehnic O versiune pe h rtie poate fi obtinut comand nd o prin fax la 32 13 66 47 49 sau prin e mail la info raqa eu tosoh com Versiune Actual G8S 01010 Instructions For Use in multiple languages are available on our website www tosohbioscience eu under the Service amp Support section A paper version can be obtained by fax 32 13 66 47 49 or e mail info raqa eu tosoh com Actual Ve

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