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1. MDL MDL CrossFire Commander 7 0 Quick User Guide 1994 2004 MDL CrossFire by MDL Information Systems GmbH Frankfurt am Main Germany Beilstein Database Copyright 1988 2004 Beilstein Institut zur Forderung der Chemischen Wissenschaften licensed to Beilstein GmbH and MDL Information Systems GmbH Gmelin Database Copyright 2000 2004 Gesellschaft Deutscher Chemiker licensed to MDL Information Systems GmbH 1988 1999 Gmelin Institut fuer Anorganische Chemie und Grenzgebiete der Max Planck Gesellschaft zur F rderung der Wissenschaften All rights reserved 03 2004 Table of Content ARESUETS seen east 34 T GENERAL nun nie 1 Wet CI EEE 34 1 1 STARTING MDL CROSSFIRE COMMANDER 7 ccccseseeseeseseees 1 42 GRID VIEW resonant inrita een nenn Eaa aA 35 12 TIE N een epneset 2 4 3 GROUPING AND SORTING cccsssccceessececeesseeecesseeecseseeeesseeeens 36 EC ONE GION e 3 4 3 1 Working with a grouped hitset enenen 39 2 QUERY cccccccssssssssssssssssssssssssssssssesssssssssssssssssssssssssssessesssssssssnsssssssee 8 4 4 TREE VIEW nun nnnnnnneeeeeeeeeeeennenenenenenneeneeeeseesseeeeeeee nennen al AT AE MEW ech cioearene tease ngnntestecaavengaaaeuvsetaiamereiaeantcaorasniaueotoienanst 42 2 1 SELECT THE DATABASE nit ee 8 2 2 WORKING WITH THE QUERY PANE ueeeessesessennnnsnnnennennneneneennnnnn 10 5 REPORTING AND EXPORTING sssssvsssseessssssssssssssvesneeeeseoees a 2 2 1 The structure qu
2. Page 6 of 58 A An MDL CrossFire Commander 7 0 Process af Invention MDL When Commander is closed it will offer to save the parameters of your current session for automatic setting MDL CrossFire Commander Closing this application will terminate your MOL CrossFire session and delete all session hitsets Terminate your session M Automatically connect to the current server for the next SESS10N ve Click here to close Commander Check here to get automatically connected at the next start of Commander Page 7 of 58 x Powering the MDL Process af Invention 2 Query 2 1 Select the Database e m MDL CrossFire Commander Query for Server intern1 MDL CrossFire Commander 7 0 O x amp File Edit Task View Options Query Help l8j x 2 MDL CrossFire Commander TTT Results Reports Autonom Query History Open Query Clear Query Select Database Draw Structure Search Field Name in Hierarchy Query Builder Search in Beilstein 2002 v Find ge Sites r Stereo etermalauns off Predefined Search Forms Hitsets T all atoms Queries r Search gt Allow _ Beilstein 2002 11 as structure I salts i Eee D stahase E Basic Indexes PO RO En Search are L a rings JIPIEBC VAaL3bgSzE Bibliographic Information Double click to enter the Structure Reaction editor Gapin r A opes H Substance Identification Rig
3. word wo rd Cancel Help Switch on off Truncation Combine with a structure or fact search and o fand Search All Text W Truncate Clear Text antiviral and antibiotic The Text Search will search your search term in the text indexed Basic Indexes of the selected database s Operators and or next near proximity can be used Page 14 of 58 7 eer MDL CrossFire Commander 7 0 Process of invention MDL When a Text Search is started Commander displays a window to define your search Text Search l X Preview Search Plan The following bars indicate the estimated frequency of a word in the selected databases The following searches will be Please select the contexts in which you want to search your words conducted in database s Gmelin 20034 0 Upe 01 and Beilstein Search Word in Context SUBSTANCES REACTIONS CITATIONS ea cp asada Substance Reaction Data 4U Tl 46 Properties EIREA BIZIT Gmelin Ft BISUB 2003 10 upay EOS AND Substances zirilisiauie W antiviral Gmelin x 200310 Upd 01 en Citations I antibiotic Pesan antiviral AND Fr 2003004 Upd 02 picti Substances Select Context Context Select Context Substances Substances Reactions I citations Citations Beilstein antiviral AND Beilstein 2003 04 Upd 02 Se Er antibiotic len aa 2003 04 Upe 02 Citations Please note Hitsets will be
4. Compound List bo Excel Compound List to HTML Compound List to Word Compound ID to HTML as Report Compound ID to RD File Compound ID to 5D File Hits and Compound Report to HTML Hit References to HTML References of all to HTML as table References of Hits to HTML as table References of Hits to HTML as List FFA List Get Sort Hits Copy Export Hits Copy to Report w Export Settings in a Reaction Context including predefined settings Export Settings in a Citation Context including predefined settings Settings Settings Citations and Compound ID to HTML as table Citations and Compound ID to HTML as Report Procite Endnote Reference Manager Citations to Excel as table Citations to HTML as table Citations bo HTML as Report Reactions bo HTML as Table Reactions bo Excel Note the export setting to Reference Manager Software creates a file that can be imported into a Reference Manager not in its native Format If you want to create your own export setting or change an existing one please select Settings Page 49 of 58 x Powering ihe Process of Invention MDL MDL CrossFire Commander 7 0 5 2 1 Creating changing export settings Export settings Comment Compound ID to Excel as table Compound ID to Word as table Compound List to Excel Compound List ta HTML Compound List to Word Compound ID to HTML as Report Compound ID to AD File Compound
5. Comment Save Profile Enter e mail addresses of the people who should get informed about the result of a run of this alert L st pun wd hia bemenioned here click show to view Save the profile Note Only the owner of the alert can view the results Enter Comments The Alert Find feature will browse these comments Page 58 of 58 Distributed by MDL Information Systems GmbH Theodor Heuss Allee 108 D 60486 Frankfurt Germany Headquarters MDL Information Systems Inc 14600 Catalina Street San Leandro CA 94577 USA Phone 1 800 275 6094 toll free Fax 1 800 223 0801 toll free e mail info mdl com US Customer Support Europe Customer Support Phone 1 800 326 3002 toll free Phone 41 61 486 8880 1 510 895 2213 outside USA Fax 41 61 486 8889 Fax 1 510 895 6092 outside USA e mail support mdl com e mail support mdl com UK Customer Support Japan Customer Support Phone 44 1276 701 520 Phone 8 1 120 71 2655 toll free Fax 44 1276 701 501 8 1 3 3230 8027 e mail support mdl com Fax 8 1 3 3230 2761 e mail jsupp mdl com
6. ID to SD File Hits and Compound Report to HTML Hit References to HTML References of all to HTML a table References of Hits to HTML as table References of Hits to HTML as List 10 tle BAN versus Pharm Effect Export Substances in Beilstein 2003 04 Upd 02 Compounds and ALL Data to HTML as Report File Name Compound Grid_to_E Stat erat Compound Grid_to Wy Compound List to Ex New Compound List_to_H Modify an existing export setting Compound List_to w Edit Lompaund_Report_H Compound to AD AE Compound_to_D_AE a Delete an export setting Hits_and Compounds Hit References to H Copy References All Grid References Hit Grid 2 ji References Hit List Help Create an identical copy of an existing export setting ERhNvsFhamE er ff Close Page 50 of 58 lt Powering the Process of Invention MDL MDL CrossFire Commander 7 0 5 2 2 Prepare an export setting After the first information screen a screen comes up which is used to select the format of the export Export Define Format Start Define Format Define Content Finish New Export Settings not defined Define Export Format Select Prograrn File Format Select Layout f MS word as HTML file Table List Report Browser HTML f Table f ist Heport MS Excel as HTML file f Table ee f ASCII Delimiters f Literature Management Systems Reference Manager Prolite EndNote PF
7. hitset to Data Search table RR Click here to use this query as search domain refine results subset search Page 27 of 58 x gg MDL CrossFire Commander 7 0 Process of Invention MDL 2 2 4 4 Hitset Histo Test in the Hitsets Find search Fields Fredefined Search Forms E Beilstein 2003 03 SCIENCEDIRECT 1 Substances Double click an entry to use as search domain refine results subset search H SCIRUSDEMUO 4 Substances D01 440 Substances Queries 002 452 Citations G03 440 Substances Right click to Properties 004 452 Citations Open view the properties see next page Collapse All open the hitset in the results window collapse the tree if there are hitsets from more than one database present Page 28 of 58 A en the MDL CrossFire Commander 7 0 MDL Hitset Properties E Hitset Properties Copy to Report l aR r EERST Information about the hitset s corresponding query Selected database Beilstein 200211 2003 Moy 10 16 22 22 CPU 0 29 sec total charge 0 radicals 0 components 1 no impl ring closures no isotopes no IST Click here to open the hitset in the results window Open hitzet in Results window Copy query to Query Builth 4 E Click here to copy this query to the query builder Page 29 of 58 x as MDL CrossFire Commander 7 0 Process af Invention MDL 3 Search 3 1 Start a
8. of the reaction in a reaction hitset can be displayed included in the display and or in a separate window Reaction 27 001 Hit 18 10 x Reaction ID 2073462 Reactant BRN 2050330 methyl 4 isopropylphenyl propionate N E Product BRN 3590020 5 2 isobutylphenyl propionic acid ai No of Reaction Details 6 y RX ID 2073462 e nn i ee ras 3 o i 0 3 EOE Jf SN Soka tn ER en Restart i The display in a separate window can be toggled on off by pressing the function key F2 on the keyboard by pressing the Show Button in the button bar View Show D Yard Bl List Get Sort Hits Copy D Export Hits Copy to Report or using the menu View Structure in separate Window Page 42 of 58 A esa MDL CrossFire Commander 7 0 Process of Invention MDL To include structures in the display use the menu View Structures included view Options Window Help arid view I List view F4 w Open Hitset in Grid view All Fields The structures of all substances and reactions described in a citation can be viewed Identification Data only as included structures Hit only Select User view F Define User View Highlight Hit Terms Selected Hits only oto Hit The Field Availability provides information how much entries for which field are present in the record for the selected substance reaction or citation and links to get directly to these data s Structures included w Structure i
9. u r r r u u Choose the relation is starts with ends with contains lt gt gt exists Operator to connect the definitions with and or proximity not near next 99 66 99 66 Cancel Type the value or word you are looking for in the specified field To view and select the content of the Page 20 of 58 lt Powering the Process of Invention MDL CrossFire Commander 7 0 MDL 2 2 4 Using the tree The tree on the left side of this Window has multiple functions and offers various options to work with Commander Search Field Name in Hierarchy r Find Hitsets Queries Fredefined Search Forms E Beilstein 200303 H Basic Indexes Substance Bibliographic Information References Chemical Data Physical Data Pharmacological and Ecological Data W Show Help for Search Fields Text in the Forms 2 O SY Find Search Fields Fredefined Search Forms Queres Hitzetz z Bibliographic Data gt Substance Identification Data Molecular Formula Search z Reaction Data Physical Data z Spectroscopic Data 2 Fharmacological Data 2 Ecotoxicological Data i Solubility Data Sort Entries above by Priority Browse and use the Database s Datafields to formulate your query Use the Predefined Search Forms PSF to formula
10. w Highlight he Terms Molecular Formula C4gH1g02 Selected Hits only Molecular Weight 206 28 Goto Hit Pharmacological Data 6 of 376 ajo Effect anti inflammatory Structures included Species or Test System Balbic mouse w Structure in separate window F2 Sex ss female Route of Application epicutaneous Reactions Kind of Dosing ee on mouse ear at conc of 1 percent given 15 min after treatment with skin Substance as Reactant only Method in vivo mouse ear swelling test ears of mice were treated with 2 percent DNCB ear Substance as Product only Update Dates included This View can be achieved as well using the View Button in the Button Bar Field Availability included View hit w Show Grid EB List C Field Availability in separate window FS Define Show Hitset History F pala Show Tree view F3 w Show Status Bar Page 45 of 58 x sa MDL CrossFire Commander 7 0 Process af Invention MDL The GEX Feature is designed to easily find related information to the current hitset Example Get All Related Reactions from a Substance Hitset Get All Related Reactions Get w Sort Hits Copy Export Hi For f the curent Substance hit 1 Et All Related Substances Not available in a Reaction Hitset Get All Related Reactions i all Substances in the current hitset 003 Not available in a Get All Related Citations Citation Hitset get all related Reactions
11. where the orginal Substances Get Substances by Regha Get Reactions by Regha Get Citations by Regha occur as ether reactants or OCCU as reactants occur as products Jump directly to a Registry Number Cancel en mentioned in the text Find all Reactions in which the title substance is involved occur as either reactants or products Find all Reactions in which the title substance is starting material occur as reactants occur as products Find all Reactions in which the title substance is product Page 46 of 58 lt gg MDL CrossFire Commander 7 0 Process af Invention MDL 5 Reporting and Exporting 5 1 Reports The reporting of selected information into a simple web like form has been extended in CrossFire Commander 7 The items that can be reported are selected information from a hit display Queries and Information about search results and progress Reporting selected Facts In the Full Display view each field 1s equipped with a Title Bar on top that is used to select factual data Select Data for reporting by checking this box Reaction 1 of 2 Reaction ID Gf Tiid Reactant BEM 8687490 1 hydrox 2 3 dihydro 1 A 3 4a 5 triaza fluoren 4 one Product BEM E6 27045 3R 3 44 5 triaza lloren 4 one Several facts can be selected separately and reported in one step additional facts can be appended to an existing report as well Clicking on the button or a right mouse click anywhere inside the fac
12. OL Information Systems GmbH Al rights reserved Ayvallable contexts SAC Substances Reactions Citations Current context S User Tights A All Read None Data Structure staecor dat Version 4 06 Information about the selected Database IF you have selected multiple databases the tree All Search Fields offers only fields common to all databases Fields available in one database only are hidden Kancel Help Page 9 of 58 x Peering e MDL CrossFire Commander 7 0 MDL 2 2 Working with the Query Pane Structure Search Three Structure Editors can be used to draw a structural query for use in MDL CrossFire Commander 7 0 The CrossFire Structure Editor ISIS Draw 2 5 and MDL Draw To select the Editor of your choice please use the menu Options Select Structure Editor Options Query Help Select Structure Editor i x Structure Editors Select Structure Editor Define StructurelReaction view Define Preferences f MDLISIS Draw onnet bo Server intern Disconnect From Server interni C MBL Draw possibly not installed Define Server Profiles C MOL CrossFire Structure Editor View Server Communication Check Server Connection Cancel Help Register Products Change the Group Name c For individual guides to the structure editors please visit http www mdl com Page 10 of 58 N E MDL CrossFire Commander 7 0 Proc
13. Query Help Select Structure Editor MDL CrossFire Server Profiles selected defaulep x Define Structure Reaction view Define Preferences Close Connect to Server default Disconnect From Server default wiew Server Communication Check Server Connection Register Products Change the Group Mame Create a new profile or edit an existing profile Page 3 of 58 x eer MDL CrossFire Commander 7 0 Process of Invention MDL Enter the server information ask your administrator for details if needed MDL CrossFire Server Profile unnamed prf f x MDL CrossFire Server Profile unnamed prf x Server Communication Script Editor Server Communication Script Editor unnamed x Forget user id passwordfor the server 7 Port Number fon Inhibit password change for the server Communication product information pizh Info about loaded Windows Socket OLL Host pour served Version 1 1 MaxSock 3276 Description WinSock 2 0 SysternStatus Running Yendorlnfo lt not available Firewall Connect via Firewall Firewall parameters Cancel Cancel Server information Communication parameter if needed Page 4 of 58 A An MDL CrossFire Commander 7 0 Process of Invention MDL To connect to the CrossFire Server please choose Options Connect to server lt name of your profile gt BEE Options Query Help You can also use the Co
14. S BSD File Beilstein Structure and Data Format Commander SD File Structure Data Format gt SIS Base AD File Reaction Data Format gt 15157 B ase f Start MS Word ft No application started for Start Browse To Clipboard To File lt prompt user Change Settings lt Back Cancel Help Set Program Layout and Format of the export Set delimiters Tabs Blanks Commas etc for an export to ASCII or to an import file for a reference manager using the select box Delimiters in an ASCII file x for Table Format for List Format Separator TABS Header Trailer none BLANK LINE Cancel Help Define behaviour of the target application starts automatically when exporting do not start or start in a different application Define handling of the exported data hand over to application via Clipboard no file is created or store in a file name conventions can be defined using the Change Settings button Page 51 of 58 x Portage MDL CrossFire Commander 7 0 Process of Invention MDL Export Define Content me x Each Include image of the title compound or reaction Crudu ee is e a m the separate structure Start IM Include images of title structuresreaction window OMe anor view I Include images of referenced structures Define Format T Include images of referenced reactions Include images of the compounds
15. abled disabled in the Menu Query Query Help Extended Structure Query Options External Query Handling Switch on off AutoSearch wf GuboSearch ON w Stop AutoSearches after ist result _ A Set AutoSearch to stop when a first hit is found equals find closest hit Show results of a multiple search i w Show Warning Multiple Database Search Clear Query History on Exit Page 33 of 58 x A MDL CrossFire Commander 7 0 Process of Invention MDL 4 Results 4 1 Overview MDL CrossFire Commander Beilstein 2003 04 Upd 01 Q01 Substance 1 of 127 Oj x fea File Edit Task Yiew Options Window Help l x z MDL CrossFire Commander History Print Hits gt ri Substances hit 1 of 127 Potter eee eee eee eee eee eee eee eee Hit 3 BRN 48454 C12H13N5 Result Tree i IE a Substance Identification Hitset Family amp so _ s abana pu Beilstein Registry Number 609154 Beilstein 2003 03 o Beilstein Preferred RN 4886 13 9 Beilstein 2003 04 CAS Registry Number 4886 13 93 Beilstein 2002 1 0 a Chemical Name 3 5 bis methylsulfanyl isothiazole 4 carbonitrile Beilstein 2002 10 Upd 01 Autoname 3 5 bis methylsulfanyl isothiazole 4 carbonitrile Beilstein 2002 10 Upd 02 u olecular Weig Lawson Number 31457 292 Hi D il aved hitsets Alert ritsets Type of Substance het
16. ck to enlarge the grid to a full table erh ical ewan eigenes Type the field code directly into the grid ry a alternative to copy by double click in the tree Fredefined Search Forms Hitsets Sea Bll i T e ARA Munie YP Enlarge Advanced Search Clear Table W make er Operator I Fig Relation Field content bist E Substance 1 JS Etfect PHARM E es C E Bibliographic Information H References ye r H Chemical Data E Physical Data E Pharmacological and Ecolagigs Double click E Pharmacologic gees Type the value or word you are looking for in the Effect specified field To view and select the content of the Endpoint of Effect field use a Species or Test System sharks with a ends with contains Route of Application Concentration Kind of Dosing je Exposure Period Further Details Half life Time gt Type r 4 W Show Help for Search Fields Use with numeric fields values Operator to limit the search to records with entries exists in a certain field e g NMR must exist Note not applicable for all fields Page 19 of 58 x Powering the Process of Invention MDL CrossFire Commander 7 0 MDL The Enlarge Feature enables complex queries using multiple fileds from the Database Query Builder Data Search Operator EE m A ee E i Type the field code e g RX ID PHARM E field use
17. click the hitset and select Sort Group Query Wii Reports Alerts AutoHom Grd GA List Get w Sort Hits Copy Oi Export Hits Sort or Group ae 4 x Hitzet 103 Beilstein 2003 04 Database Beilstein 2003704 H Saved Hitzets Alert Hitsets Current Status Junsorted E Session Hitsets H 0 903 0 fo art Sotby Group by Go bo Hit Ascending Go to End Descending Collapse Properties Ascending Hitset Farnilyt3 via Descending Save as Behan f Ascending SorkiGroup Descending Get All Related Substances Get all Related Reactions Get All Related Citations Page 36 of 58 lt An MDL CrossFire Commander 7 0 Process of Invention MDL Sort or Group the Hitset Hitzet LOS Database Beilstein 2003 04 Current Status unsorted E Sorth CG h Click here to select the action for the top Sort by roup by e ER gt Fee level Sort by or Group by Display of current status Hitset Database and current status Unsorted sorted sorted grouped C Descending Grouping is available on 1 level only subgrouping is not possible Then sort By Ascending A grouped hitset can be sorted Descending Then sort by C Descending Cancel Help Ascending Page 37 of 58 x pa MDL CrossFire Commander 7 0 Process af invention MDL Sorted Hitset Sorting Crite
18. d Next Find First Back Forward Close Chemical Name CN locate intree select for search Description The field Chemical Name contains complete chemical names from various Sources the preferred name the IUPAC based name used in the Beilstein Handbook names from the original publication Double click to select the field for search it will be copied into the Data Search Grid Page 22 of 58 EN Powering the Process of Invention MDL Search Field Name in Hierarchy Chemical Hame Fredefined Search Forms Hitsets Search Fields Queries ag Beilstein 2003 03 a E Basic Indexes aj Substance Beilstein Registry Number Beilstein Preferred AN Fragment Molecular Formula gt Molecular Formula 4 W Show Help for Search Fields Note from here you have to use the Find Next Button to find the next occurrence of your search term in the field help MDL CrossFire Commander 7 0 The Feature Search Field Name in Hierarchy is a function to help you to locate the data field that contains information about a term that is entered into the text field Note you have to click the Find button with your mouse If the search term cannot be found in the field names the search is extended to the field help example term preferred name Gearch Text in Field Help x Find Next Find First Back Forward Chemical Name C N select for search Click
19. erocyclic It etal S Session Hitsets Constitution ID 565891 Q Q01 127 Substances Tautomer ID 582611 Beilstein PlusReactions 2003 03 Beilstein Reference 5 27 6 27 Beilstein PlusReactions 2003 04 Beilstein bstracts 2003 03 BRN 609154 Field Availability List 1 10 an For Help press F1 idle STRUCT Code Field Name Occ el lidle ALL Sub A age 34 of 58 lt E MDL CrossFire Commander 7 0 Process of Invention MDL 4 2 Grid View The Grid View provides an overview over the structures reactions or citations of a hitset Hit I BRM 204 7496 C12H160 Hit 2 BRM 6368972 C412H1602 Hit 2 RAID 3560738 ao Grid View of a Substance Hitset Hit 2 5535702 Journal Chia Peter 5 K Ekstrom Alfred Liepa Imants Lindow Leonard F WcPartlin Man etal AJCHAS Austl Shem EN 44 5 1991 737 748 Hit 3 5580551 Journal Borisova E Ya Komarov Y hd Lukashova L A Cherkashin M 1 Kopytin Y S 49 251 DASKAJ Dokl Grid View of a Citation Hitset Double Click an Item in the Grid to see the hit details or use the buttons Grid and List Eis Mel to switch between the Grid and the Hit Details Page 35 of 58 x A MDL CrossFire Commander 7 0 Process of Invention MDL 4 3 Grouping and Sorting A Hitset can be sorted and grouped by the values of selected fields Select the Hitset in the tree and click the Sort Hits Button or right
20. ery formulation nn 11 ARERO ee ee ee 47 RW Text SCOT TNEREREUIE RENNER EINER HENE NE REIFEIN N aai 14 32 ESPORT essen ee ende 49 SI SEIDEL een ee 18 5 2 1 Creating changing export settings 50 BPE iO SNS METER een 21 3 22 Prepare an Opor SEINE soosse a ES 31 3 SEARCH KO 30 IA CL N een a I THL REPORT PAN ee end 54 DU ART A SER N ehe EE csenueaes 30 3 2 SEARCH PROGRESS ILL 32 GO ALERTS sn 56 lt NEN MDL CrossFire Commander 7 0 Process af Invention MDL 1 General 1 1 Starting MDL CrossFire Commander 7 e To start Commander from whichever platform you are using double click the icon on your desktop or select in the Windows start menu Programs MDL CrossFire Commander 7 Set Program Access and Defaults CR te ee MDL Autorom Help LS MDL ISIS Draw 2 5 Standalone MDL BoillsbeineR sam q MDL CrossFire Commander 7 0 Programs 4 Documents ve A Po Femmander Help Eh Settings BA D l Ha MOL CrossFire Datalink B MDL Gmelin Reference Guide GS Search g I Help br Run amp Log OFF root Cy Shut Down Page 1 of 58 x eer MDL CrossFire Commander 7 0 Process of Invention MDL 1 2 Overview MDL CrossFire Commander Query for Server sorting f Oj x cal File Edit Task wiew Options Query Help je re MDL CrossFire Commander SULT Results Reports Alerts AutoHom Quer History Open Query Clear Query Select Database Draw S
21. ess of Invention MDL 2 2 1 The structure query formulation Free Sites z hetero atome all atoms gt Search Stereo z off Allow as structure salts StructureHeaction Search as reactant L an Si Double click to enter the Structure A eaction editor as product we J Aight click to copy or paste the structure Au as reagent radicals a catalyst mixtures Double click to open the structure editor as solvent telat Markush or Clear Structure Extended Options paste a structure from the clipboard note not all information can be pasted Options for structure queries Draw a structure or a reaction and return to Commander Page 11 of 58 x iik MDL CrossFire Commander 7 0 Process af Invention MDL A chemical structure can be searched with the following options Free Sites hetero atoms J Use these options to set free sites on hetero atoms on all atoms for the entire molecule all atoms c amp gt If AutoSearch is enabled these options will be set automatically during the search see page 33 Note free sites on individual atoms can be set in the structure editor Automatic settings Free Sites on all Atoms is interpreted as a substructure search To allow this the options Allow salts additional rings isotopes charges and radicals are set automatically Each of them can be unchecked if not wanted T a salt
22. given in separate Different contexts may give different hits Search more than 1 context to be windows comprehensive Results from different databases and contexts are displayed in different windows Words from bibliographic data Author Patent Assignee Journal Mame Patent Number 1 are NOT searchable in SUBSTANCES or REACTIONS Please uncheck words inthe left column and use DATA SEARCH for these words to get records Substance property data and reaction data are not searchable in Citation Contest Ei E Cancel Help Page 15 of 58 Pa MDL CrossFire Commander 7 0 Procesi af invention Use these check boxes to select or deselect a term for search Example Search Word j SUBSTANCES Substance es BIREA AI UE Deselect a term a if the occurrence wir a antibiotic The ia of the bars relative occurence context 1s too low or not present Sefect Context vs stances F Reactions Women 1 Citations Gmelin 20034 0 Upd 01 omein 2o03 10 upa o1 Beste Uped O24 The colours indicate the occurrence of the search term in the individual databases Select context for search using the check boxes Page 16 of 58 lt ring te MDL CrossFire Commander 7 0 MDL The selection of search term and context by using the checkboxes leads to a search plan which is displayed at the right side for a convenient overview and to enable a preview or relevance check befo
23. he Start Search Button Note you can not start a search using the Return Enter Key Page 31 of 58 x ag MDL CrossFire Commander 7 0 Process af Invention MDL 3 2 Search Progress Click Cancel to stop a search Already The search progress in displayed in a new window finished hitsets are available after canceling Multiple Database Searches Tasks running press Pause key to cancel total charge 0 radicals 0 components 1 mno impl ring closures no isotopes no IST a a Beilstein 2003041 Substances pe original structure and BlSUB anti or BIPHARM anti and Sc piano omeinzoean substances Ao emo oretinzo0sie4 otstions earannan ent ee Use checkboxes to select a hitset for view To Report Cancel Definition of each Query Cancel and return to the Query Builder View selected hitsets Copy this Window to a report Page 32 of 58 A gg MDL CrossFire Commander 7 0 Process of Invention MDL When a search is finished the top of the Search Progress Window changes to allow browsing of the sessions s searches Multiple Database Searches i IOl x Your recent searchles had the following resulta Hitzet Family 3 of 4 Previous Use these buttons to browse searches from the current session AutoSearch If AutoSearch is enabled Commander will refine a structure step by step to find the closest hit AutoSearch can be en
24. ht Hit terms w Open Hitset in Grid Views All Fields Identification Data only Hit only Select User view r Define Use Bil foto Hit w Skruckures included Search Term highlighted in text w Structure in separate window Fz NM All Reactions Substance as Reactant only anti inflammatory Effect Species or Test System Substance as Product only Method carrageenan induced paw oedema method percentage reduction Update Dates included in edema at 3 h was determined w Field Availability included Field Availability in separate window FS Show Hikzet History F Show Tree view F3 w Show Status Bar Page 44 of 58 feat MDL CrossFire Commander 7 0 Process of Invention MDL The display can be reduced to show the substance or reaction identification data and the fact that includes the search term only using View Hit only View Options Window Help Grid view List view F4 E Substance Identification HitsetFamiy Pol Ba Beilstein Registry Number IEUFAR _ Ioj x Beilstein Preferred RN 15687 27 1 CAS Registry Number 15687 27 1 51146 56 6 51146 57 7 Chemical Name 4 sobutyl alpha methylphenylacetic acid Benzeneacetic acid alpha methyl 4 2 r 4 jsobutyl co methylphenylacetic acid a methyl 4 2 methylpropyl benzeneace 2 4 isobutylphenyl propionic acid Define User View ibuprofen a Lf Autoname 2 4 isobutyl phenyl propionic acid
25. ht click to copy or paste the structure as reagent E radicals Click this button to aS reagert Chemical Properties as catalyst mixtures select one or more cs Physical Properties as solvent relat Markush H Pharmacological and Ecological Data V Show Help for Search Fields For Help press Fi databases for your search If you are not connected this Clear Structure Extended Options button will look like and Search All Text Truncate Clear Text eee and Search Fields Advanced Search Clear Table w lt Select and edit Search Form Search Field Query or Hitset from left box and append to query Clicking this button will connect you and open the Database Selection Search Context Substances Z Page 8 of 58 Powering the i MDL Process af Invention MDL CrossFire Commander 7 0 The Database Selection Window allows you to select one or more databases for your search Select databases to be searched Please check one or more databases Feilstein 2003 0 Ed Available Databases check the Checkbox to select Please note x MOL CrossFire Server Software Yersion 6 0 Build 19 Copyright c MDL Information Systeme GmbH 19966 2002 Current database is BS03034E with 9773343 compounds Beilstein Data Copyright c 1399 2003 Beilstein Institut zur Foerderung der Chemischen Wissenschaften licensed to Beilstein GmbH and M
26. i Beilstein Data Copyright c 1988 2003 Beilstein Institut zur Foerderung der Chemischen E nort html Wissenschaften licensed ta Beilstein GmbH and MOL Information Systems GmbH All rights tet reserved S Exports sub html substance Identification Beilstein u on 2003 04 Upd 02 Substances 05 hit 1 BRN 2049713 Tree select Report or Export to be Beilstein Registry Number 2049715 displayed in the main display Gran sin Preterread Bh Ha The currently active Report is Main nn Content of the selected Report or Export All Hyperlinks are active displayed in bold Chemical Mame 4 lsobuty alpha methylphenylacetic acid Right mouse click offers Settings and Delete Benzeneacetic acid alpha methyl 4 2 methylpropyl Sort Entries above by Name J isohutyl c methylphenylacetic acid For Help press F1 0 ie A Page 55 of 58 lt E MDL CrossFire Commander 7 0 Process af Invention MDL 6 Alerts MDL CrossFire Commander 7 0 offers an Alert feature keep me posted feature It is designed to retrieve results from a query that is run against the new data of an update To create an Alert first create a Query in the Query Builder In the button bar than click Create Alert MDL CrossFire Commander Query for Server r6 Oj x 5 File Edit Task view Options Query Help 81 x 4 MDL CrossFire Commander Query History Open Query Save Quer Print Query Clear Query Select Database Draw Struc
27. ing this link will update the tree H Description The field Chemical Name contains complete chemical names from various sources the G ETERR Es ithe IUPAC based name used in the Beilstein Handbook names fram the original publication el Page 23 of 58 x faa MDL CrossFire Commander 7 0 Process af Invention MDL 2 2 4 2 Predefined Search Forms PSF The Predefined Search Forms summarize the fields of a specific area of interest in an easy to use form Text in the Forms Find Use the search feature to locate a specific topic in the forms search Fields Queres Hitzets Fredefined Search Forms Bibliographic Data Substance Identification Data Molecular Formula Search ae on 4 Double click an entry to open the form Physical Data Spectroscopic Data In Pharmacological Data z Ecotoxicolagical Data Solubility Data ener oe anaes by Priority lt Sort the Search Forms in alphabetical order or by priority Page 24 of 58 Powering tire EN MDL CrossFire Commander 7 0 Process af Invention MDL Testin the Forms Find Search Fields Queries Hitsets Fredefined Search Forms Cross Search Common Indexes z Cross Search Identification Cross Search Bibliographic Data 3 Cross Search Reaction Data i Cross Search Physical Data Predefined Search Forms for simultaneous searches ove
28. ld or select the field and use H Entry Date Tomen the gt gt button to add it to the view layout H Liquid Phase El Transition Foint z of Liquid Modifical E Gases l Other Physical and Mechanical Prope F Comment Cancel Help Page 53 of 58 7 MDL CrossFire Commander 7 0 Process af invention MDL 5 3 The Report Pane All reports are available in the first instance inside CrossFire Commander This avoids any trouble with opening a report in the various Versions of Microsoft Office and Internet Explorer or other Browsers and the report can be viewed in a controlled environment In addition all exports in html format are available in the report pane To access the report pane click the Reports Tab AutoHom For further use the reports can be viewed in the Browser or Microsoft Word Click Open Document and select the target of your choice ra MDL Crosstite ommander Query Results MEMI Alerts AutoHom Open er Print fresh a To print a reports click Print Page 54 of 58 lt gg MDL CrossFire Commander 7 0 Process of Invention MDL MDL CrossFire Commander Reports report html ld oj x E File Edit view Help jej x A MDL CrossFire Commander Query Results Dill Alerts AutoHom E e De IC EE T Print SER H a PETE EE ED OU ESO GE ka 1 Report Report Report Title z F NEPON Kae html Pa l SEEE l l eek
29. n separate window Field Availability List 1 10 of 30 All Reactions Code Field Name Occ Substance as Reactant only PHARM Bioactivity Pharmacological Data 54 Substance as Product only BIOD Ecological Data Biodegradation 3 RX Reaction 65 Update Dates included RSTR Related Structure 1 i Feud nae PUR Purification 3 w Field Availability included CNF Conformation 1 Field Availability in separate window FS IDA Interatomic Distances and Angles 2 z MP Melting Point 10 Show Hitset History F CRYPH Crystal Phase 4 w Show Tree view F3 CSYS Crystal System 1 P Showy Shatus Bar It can be viewed included in the text or in a separate window Use the menu View Field Availability included to include it in the text Press the function key F5 on the keyboard or select View Field Availability in separate window to toggle on off the setting of your choice Page 43 of 58 7 E MDL CrossFire Commander 7 0 MDL When conducting a factual search or a text search combined with a structure or without the findings for the search term in the hit can be used for better overview in two ways Example Search for Ibuprofen as structure with the data constraint pharmacological Effect anti inflammatory Operator Field name Relation Field content antiinflammatory View Options Window Help i g Grid View f List View F4 The term can be highlighted using View Highlig
30. nnect Button Select Structure Editor MDL CrossFire Commander Query no Server connected Define Structure Reaction View File Edit Task view Options Query Help Define Preferences ns MDL CrossFire Commander CHE Results Reports Autoltom Connect to Server default Query History Open Quen Save Quer Print Query Clear Quer Draw Structure Disconnect From Server default Define Server Profiles View Server Communication Check Server Connection H On first logon you will be prompted for your user ID and password Register Products Change the Group Name Server User ID and Password x Logon to MOL CrossFire server Host VOU Server User ID user ID Password i pasword Check here to save your User ID Password for automatic logon ave user id and password cercei Page 5 of 58 x asa MDL CrossFire Commander 7 0 Process af Invention MDL If you want to change your saved User ID password select Options Define Server Profiles and select the profile for which you want to change your credentials Check here to get prompted for User ID and Password MDL CrossFire Server Profiles selected defauleper 63 MDL CrossFire Server rofile C Program Files XFC62 group prh defans 3 Server Communication cript Editor default prt Ii Forget user id password for the server Inhibit password change for the server pou SEIWET Lancel
31. or reactions that are referenced in the data of the hit Define Content Facts IW Facts Select Facts to View Replace Field Names Toe It is important that the View is defined Views simple ud Please see next page Mot more thar All occurences per fact Finish T Hit only Additional Data incl Field Availability Please check if you want to include the Field Availability List and or the List of I incl References New Export Settings not defined lt Back Cancel Help Page 52 of 58 A aia MDL CrossFire Commander 7 0 Process of Invention MDL 5 2 3 Selecting a View It is important to define which data fields shall appear in an export Click Select Facts to View and New to define the fields for your export and select the fields from the datastructure Example molecular weight and boiling points Select Fields E Available Fields Find Selected Fields Remove All i ae E Beilstein 2003 04 Upd 02 H Entry Date 2 Update Date E Substance Identification dee Molecular weight H Che Database Structure Physical Properties Phys Single Component System Single Component System Physical State E Structure and Energy Parameter Liquids Physical State Boiling Port fl Crystals s5 PE oiling Point l Liquids Boiling Point o gt Pressure Double click the fie
32. r multiple databases Sort Entries above by Friority Page 25 of 58 x eee MDL CrossFire Commander 7 0 Process of Invention MDL 2 2 4 3 Query History x Tent in the Queries i Find Feature Find Query by name date etc see next page Find Fredefined Search Forms Hitsets Search Fields F My Queries Sample Queries E Previous Queries 1 Se E Queries on 2003 Nov D7 4 E Today s Queries 8 l H a Queries from last session either Date or Yesterday s queries e 3 14 48 41 1 hits 7 A ey a Queries of the current day So Toe its 6 14 59 34 0 hits 7 14 53 34 33 hits in Q05 amp 15 00 05 3 hits in ODE Double click an entry to view the Query see next page Page 26 of 58 lt NEN MDL CrossFire Commander 7 0 Procesi of Invention MDL ead Query Properties Copy to Report Query No 8 Hits in 006 Number of hita 3 Substances Selected database Beilstein 200241 Execution 2003 NMov 10 15 00 05 CPU 0 29 sec User defined query name comment structure original structure total charge 0 radicals 0 components 1 no impl ring lozures no isotopes no IST Query Information Find feature searches here Comment field contains factual queries Query Definition and Conditions Click here to copy this query into the query builder Copy query to Query Builder Append
33. r of the group Page 40 of 58 lt Powering phe Process of invention MDL 4 4 Tree View Beilstein 2004 01 Saved Hitsets Alert Hitsets Session Hitsets Q 901 8 Substances lsobutpl alpha methulphenplacetic acid 5 2 irshutyiphenylpropionic acid is IE Substance z 66 Reaction 1 Related Structure 3 Purification 1 Conformation s 2 interatomic Distances and Angles 10 Melting Point u 4 Crystal Phase Z 1 Crystal System z 2 Space Group u 2 Density of the Crystal r Enthalpy of Fusion u 1 Other Thermochemical Data ba 10 Optical Rotator Power 2 Circular Dichroism 2 23 Nuclear Magnetic Resonance 3 Infrared Spectra MDL CrossFire Commander 7 0 On the left side of the screen the tree view provides fast navigation through saved Hitsets and Session Hitsets Select the Hitset you want to see and the main screen switches to Short Display Click on to drill down to details ultimately to field level Click on these details to display them in the main screen Page 41 of 58 x R MDL CrossFire Commander 7 0 Process of Invention MDL 4 5 Detail View The detail view contains all data about a compound citation or reaction that are available in the database The structures contained in a substance or reaction hitset the structure of the title compound in a substance hitset the graphical display
34. re starting the search Search Plan The following searches vvill be conducted in datahbasels Gmelin TOSI OREO anc Benstein 2003 04 Upd 02 4 searchles Gmelin 20031 0 Upd 01 a T Substances Armellini antiviral AMO nen 4 searches will be conducted resulting in 4 hit sets Beilstein 2003 04 Upad 02 Eu ar Substances Beilstein 2003 04 Upad 02 EN a Citations Hit amp ets wril be given in separate windo Page 17 of 58 x a MDL CrossFire Commander 7 0 Process af Invention MDL 2 2 3 Search Fields Options for the Query Grid see next pages Clear Table WF and Operators to Delete Cells connect with Delete Rows a Structure or Delete All text search Search Fields Advanced Search Clear Table WF lt Select and edit Search Form Search Field Query or Hitzet from left bos and append to query Click here to open the Grid or double click a Provides a text field where a query in command language can be entered field in the Search fields Tree For experienced users please see page X Syntax lt field code gt lt value gt and or next proximity lt field code gt lt value gt Example PHARM E antitumor or PHARM E anticancer Page 18 of 58 lt NN MDL CrossFire Commander 7 0 Process af Invention MDL Search Field Selection There are two ways to enter a field for search into the Grid Double click a field in the Datastructure tree New button cli
35. rion Beilsteinl 2003704 Saved Hitzets lert Hitsets Session Hitsets zp Q 004 166 Reactions by Reaction code medium A MLDODE E 2 Preparation H 3 Preparation Grouped Hitset E Beilstein 2003704 5 Saved Hitsetz Alert Hitsets Session Hitsets Grouping Criterion Q Q04 162 Groups by Product BAH R PERN 4 101 9062 201 22595 311 55345 l a Value of Grouping Criterion that defines the group Page 38 of 58 lt gg MDL CrossFire Commander 7 0 Process af invention MDL 4 3 1 Working with a grouped hitset In the tree E Beilstein 2003 04 Saved Hitzets lert Hitsets E Session Hitsets F Q 004 162 Groups by Product BRN RA PBAN E 11 9062 E ill 22595 Left Mouse Click a a Click the Hitset top level t a ick the Hitset top level to see an Az baa overview of all groups first group member oll 105117 and group definition in the Grid View 611 105594 H AZ 109273 Click a hitset to see an overview of a group group members Group Number Number of group members value of sorting criterion for this group 7 2 109273 Product BRN Page 39 of 58 x Powering ihre Process of invention MDL in the grid view Group Number ng ar Tye Number of Gro up Mem a MDL CrossFire Commander 7 0 Value of the grouping criterion bers The image shows the first membe
36. s Print Profile Impu Profile Edit Modify Query Alert hitzetz see Results Search Context Substances total charge 0 radicals 0 components 1 no impl ring closures no isotopes no 1ST Alert Query Definition Text Search and Text Search search term Automatic truncation right Data Search and Effect PFHARM E ot Database Beilstein Frequency after each update Today EEE Last rum Alert Options Hits last run Shoe First run date Send results to Enter your own E mail address rou Send a copy to Enter further E mail addresses andor existing alert E mail liste separated by semicolons Comment Sort Entries above by Mame For Help press Fl lidle Page 57 of 58 x eer MDL CrossFire Commander 7 0 Process of Invention MDL Alert Options Define the frequency of the alert run After each update hi Deactivated After each update Define the Database on which the Alert shall run weekly no multiple Databases Enter the date on which you a wish the first run of the alert on Database Bein Frequency after each update First run date Today l Last run Hits last run Show Send results to Enter pour own E mail address ou are the owner of the alert r Send a copy to Entf further E mail addresses andor existing alert E mail lists separated by semicolons r
37. s addl ring Isokopes changes radicals mistures relat Mark ush Free Sites hetero atoms ITS SI 414141 Page 12 of 58 lt gg MDL CrossFire Commander 7 0 Process af Invention Search the drawn structure as auxiliary in a reaction recommended context Reactions MDL Search i Search the drawn structure as such recommended context Substances as structure as reactant u Search the drawn structure as reactant explore it s chemical reactivity recommended context Reactions as product as reagent as catalyst Search the drawn structure as product explore the preparations recommended context Reactions as solvent Note the option search as reagent as catalyst as solvent is not available for all databases Any stereochemical information in the drawn structure will be ignored Any stereochemical information in the drawn structure will be searched exactly as drawn Any stereochemical information in the drawn structure will be searched as relative stereochemical information The racemic mixture is searched Page 13 of 58 7 eer MDL CrossFire Commander 7 0 Process af invention MDL 2 2 2 Text Search xj Word truncation IM Use right truncation Use left truncation The Text Search offers a search for a keyword expression in the Basic Indexes that contain text ou may use 1 character or any charac ters for left right and inner truncation e g word
38. search Before a search is started it is critical to select the context of your search A search in CrossFire Commander 7 0 can be done in one of three contexts Choose this context if you Choose this context if you Choose this context if you have drawn a structure or if have drawn a structure and are looking for an Author a you are looking for data or selected as product or as publication or any other properties of a compound reactant if you have drawn a publication related topic reaction or if you are looking for data and properties of a reaction The context has to be defined on the query formulation page SE EETIET A Substarices Start Search Reactions Citations 4 Page 30 of 58 lt An MDL CrossFire Commander 7 0 Process af Invention MDL At each start of a search MDL CrossFire Commander 7 0 compares the query with the selected context If the query is unusual for the chosen context Commander will prompt you to verify or change the context Select Search Context x The context of your query it different from the context you selected Recommended context Substances Search in Substances Or search in this context Reactions r Search in Reactions Cancel Reactions Click here to search in the recommended context Help Click here to search in a different context of your choice Fr l Each search can be started in two ways Press F7 wi or click t
39. t opens a menu Page 47 of 58 a MDL Pouserneg ihe Process af Invention w Issue the Structure or Reaction Picture s Issue Structures as Bitmaps Issue Structures a5 Molfiles The reports are available inside the Commander MDL CrossFire Commander 7 0 Add the selected facts to the report Alm al Selected Facts to Report tesk1 html Open the Report Set Report File Set Report Title Clear Report File Open the report in your Browser Define the file name and location for the current report Set the title header of the report Copy Fact to Clipboard Selected Facts to Word Clear the current report Use the selected facts in the Windows Clipboard or Microsoft Word directly Select all the Facts Field Availability List Select all Facts Unselect all Facts selected Query Results Alerts Autonom Furthermore Queries Search Status Information and other information can be reported Look for the button To Report Page 48 of 58 A Powering the MDL 5 2 Exports Process af Invention MDL CrossFire Commander 7 0 Hitsets and Hits can be exported to various targets Clicking Export Hits in the button bar opens a menu with items depending on the context of the hitset Show C Grd E I lea Export Settings in a Substance Context including predefined settings Settings Compounds and ALL Data to HTML as Report Compound ID to Excel as table Compound ID to Word as table
40. te your query Test in the Queries 7 Find Predefined Search Forms Hitsets Search Fields My Queries i Sample Queries Queries on 2003 Nov 05 4 Queries on 2003 Now 07 4 Today s Queries 4 1 14 47 54 38 hits in 003 a amp 14 47 54 0 hits 14 48 41 1 hits in 005 woe 14 48 41 0 hits Browse and use queries from the last days Test in the Hitsets Find Search Fields Queries Predefined Search Forms E Beilstein 2003 03 SCIENCEDIRECT 1 Substances SCIRUSDEMO 4 Substances 101 440 Substances 102 452 Citations Im 103 440 Substances 204 452 Citations Browse and use Hitsets from the current session or saved Hitsets Page 21 of 58 x Powering the Process of Invention MDL 2 2 4 1 Search Fields Search Field Name in Hierarchy 2 Chemical Hame Find Fredefined Search Forms Hitsets Queres Search Fields Beilsteinf2003 03 Basic Indexes Substance z Beilstein Registry Number z Beilstein Prefered AM e CAS Registry Number Bi hemical Name field to the grid or search or collapse the M Show Help for Search Fields Copy to Grid Collapse All Toggle on off the field help MDL CrossFire Commander 7 0 The datastructure of the selected database can be browsed in this tree Click on a field to see the help on this field Field Help Fin
41. tructure Text in the Forms 7 Query Builder Search in Beilstein 2003 04 Upd 02 Find Free Sites stereo hetero atoms or i Search Fields Quenes 1 all atoms Fredefined Search Forms Hitzetz Search Allow gt Bibliographic Data as structure C salts substance Identification Data C tucture Reaction Search as reactant ae ngs e Molecular Formula Search Double click to enter the StructureAeaction editor as product T Pa Reaction Data Right click to copy or paste the structure a Phusical Dat as reagent radicals Physical Data as catalyst mixtures Spectroscopic Data as solvent F relat Markush H Pharmacological Data S Ecotoxicological Data Clear Structure Extended Options Solubility Data J and Search All Text 7 u Truncate Clear Text and search Fields Advanced Search Clear Table W Select and edit Search Form Search Field Query or Hitzet from left bos and append to query Sort Entries above For Help press Fl A ge MDL CrossFire Commander 7 0 Process of Invention MDL 1 3 Connection To access the CrossFire Server a profile has to be available which includes information about the Server and a UserID Password Note these settings may have been automatically done already by your administrator To create a profile select Options Define Server Profiles Options
42. ture Modify Aler Create Alert Start Search UTIs Results Reports Alerts Autolom Search Field Name in Hierarchy Query Builder Search in Beilstein 2003 04 Find Free Sites Stered total charge 0 radicals 0 components 1 no impl ring closures no isotopes 7 hetero atoms lt Predefined Search Forms Hitsets no IST 7 all atoms pi Queries Search gt Alllow Beilstein 2003 04 asstuctue salts Basic Indexes sang m rings isotopes Substance as product O ae api ges Bibliographic Information Oe ssc r adea i as reagent References as catalyst 17 mistures Chemical Data as solvent A relat Markush Physical Data Pharmacological and Ecological Data Clear Structure Extended Options and Search All Text V Truncate Clear Text Search Term v and Search Fields Enlarge Advanced Search Clear Table W mt opao a Relation kO l Search Context Substances gt For Help press F1 idle Z MV Show Help for Search Fields Page 56 of 58 lt MDL CrossFire Commander 7 0 Process af Invention MDL The query is then transferred into the Alert Window where the Alert Options must be set MDL CrossFire Commander Alerts on Server sorting E oj x _ x Profile Name will appear in the Alert Tree Results Reports Bft Show all Profile
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