The Genevac HT-24 Series II Workstation User Manual
Contents
1. LAMP LAYER SELECTION OPERATOR CONTROLS LAMP LAYER SELECTION OPTIONS MAINTENANCE STATUS e In LAMP LAYER SELECTION you can enable or disable different lamp layers e Press ESC to leave this menu GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Select lamp layers to enable or disable Use the cursor keys to select the LAMP LAYER SELECTION and press ENTER Lamp Layer 1 Top Enabled Lamp Layer 2 Enabled Lamp Layer 3 Enabled e Use the UP and DOWN cursor keys to select the lamp layer you wish to disable or enable NOTE Top layer CANNOT be disabled if ANY other layer is enabled e Use the ENTER key to toggle between Enabled and Disabled e Press ESC to exit this screen GENEVAC LTD HELP TL to select layer ENTER to toggle state ESC to leave this menu Enable disable Lamp Layer 1 Top n10 september Page 33 of AT 7 10 1562 Issue 1 Revisio USER MENU LAMP LAYER SELECTION DPERATOR CONTROLS OPTIONS MA INTENANCE STATUS GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Ad just screen brightness beep on keypress user intervention end of run CONTROLS MENU Adjust Screen Brightness Keypress Beep On Off Off User Intervention Beeps On Off Off End of Run Beeps On Off Off GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Adjusts b2. 562 Issue 1 Revision 10 S september 2005 U a D o O If you wish to end the work session on the system go to the Select Run screen and press STOP SELECT RUN No Nane Solvent Vol Holder T xt 91 Example Etc Hex iml Deep We 40 gz 93 PURIFICATION VATERNACETONITRILE 10m 16 X 15 94 SOLID PHASE SYNTH TFASDCH mnl DEEP WE 95 COMPOUND p CONFIRM REQUEST 96 OLIGO SYA Shut down evaporator Are you sure 97 SOLUTION 98 SOLUTION PHASE 2 DCASMETHANOL iml DEEP WE 99 MAINTENANCE TEST 1 nl MAINTENANCE TEST 2 Onl GENEVAC LTD MENU JE EDIT GRAPH CLEAR COPY TO DRAIN DEFROST FLUSH OPTIONS HELP Select Run with Tl Menu Item with gt keys press START to execute Starts selected Run using parameters stored This prompt will be displayed on the SELECT RUN screen Press Y to close the system down or N to select another run e The SHUT DOWN screen will be displayed when you select the Y response e You can restart the run by pressing START at any point e You can abort Shutdown by pressing START at anytime e If you want to start a different run press STOP select N and press ESC to display the SELECT RUN screen E es S _ d z REMENE 562 Issue 1 Revision 10 September 2005
3. D E e a E A A E O E ania cadva wanesneouine 29 BUS SPS OL a E E E E EE E OEE pls natn else EE tue E E E E EE N 29 See LE n EEEE EE EEE ET T E T T E E E A T TO 30 5 8 How to enter control data cc ceccccccecccsecseeceeeceeeeeeteceeeeseeceeeeueceueegeesuecseeeaeeeueeeeeeeeeaeesaes 37 10 1562 Issue 1 Revision 10 September 2005 Page 2 of 47 Genevac HT 24 Series II Workstation Contents Continued 6 Trouble Shooting and Maintenance cccccccseccceseeeceeecceseeceeeeceuseeaueeseusesseeecsseeecseeeseeeessesensaees 42 T TSG ale salk i espe A E A A A E A E E A E E 43 8 EC Declaration of Conformity srs ctaxs ce casnisaheessiwcosmarddenideabneaenendaecuwenbowstiskadagadanabeesesuenenepcneedeeunnstaactes 45 9 S E Saat cece T ETE E E A AE A E E T E A E E AS 45 10 Warranty Statement ccccccccccseeeccececeeeeecseeceeesceauceceaeeseueesseeeceueeeseeesseueecseeeseesesusessaeeeseesessaeess 45 11 SSRI WG OMT ALO sssaaa ARAE AEAEE E EAA EAEEREN ARDANE 47 Amendment Control Form Revision Issue and Reason for Change Date Issued Number Changes to Declaration of Conformity Defrost and Drain note added January 2004 P 6 Upatedmags OO O Re 2008 8 Changes to Declaration of Conformity 21 September 2004 o Updated Waste Container images and change in Height dimensions 08 December 2004 Information on the correct use of SampleGuard Probes 28 September 2005 These instructions are subject to change wit
4. Sample Temp 1 35 ChamberHeat Off Vent Open 57G Voltage 0 CoolHeatEnableReached No Defrost Closed 57G Onboard T 0 Coo lHeat Off Drain Closed Rotor Speed 0 Dri Pure Ramp Active No Flush Not Fitted Rotor Position ii ControlPressureReached No Cond Gas T 19 Cond Core T 24 e The current status of the Cond Full T Chamber Temp 36 evaporator is displayed Door Lid Temp 25 e Press ESC to exit this screen RUN STAGE TIMERS VERS IONS Total 00 00 00 Arcom VOZ 01 Jul 21 2003 11 31 43 Evap 00 00 00 8051 V0Z 02 Stage 00 00 00 S No 12345 GENEVAC LTD HELP Press ESC to quit 5 8 How to enter control data The following pages describe how to enter run data acceptable values and options that may or may not be available for your particular setup All control data is entered from the RUN DATA screen From start up of the system and the software control screen press START to display the SELECT RUN screen Select the VIEW EDIT DETAILS option and press START to display the RUN DATA screen Use the UP and DOWN cursor keys to move between fields Unless otherwise stated press ENTER to open a field input your requirement and press ENTER again to close the field Page 37 of Genevac HT 24 Series II Workstation Run Data Locked Next Run Number Sample Holder Type Sample Volume Solvent 10 1562 Issue 1 Revision 10 September 2005 When set to
5. The definitions and scope of each symbol is as described below WARNING THIS SYMBOL INDICATES HAZARDS THAT CAN LEAD TO SERIOUS MATERIAL DAMAGE OR POTENTIAL SERIOUS INJURY gt Caution This symbol provides information about hazards that can be harmful to your health or lead to material damage a Note This symbol provides information about technical requirements which if not followed can lead to malfunctions inefficiency and reduced productivity Lil This symbol indicates that there may be a risk to sample integrity 2 2 Safety BEFORE OPERATING THE SYSTEM IT IS IMPORTANT THAT THE FOLLOWING NOTES T ARE READ TO ENSURE THAT THE IMPLICATIONS TO THE SAFETY OF PERSONNEL OPERATING THE SYSTEM AND FOR THE PROTECTION OF SAMPLE INTEGRITY ARE UNDERSTOOD Samples in the evaporator chamber are subjected to accelerations of up to 500G with a maximum load capacity of 1 5 kg for each rotor position The following precautions should therefore always be observed 2 3 Safe loading of evaporator Never exceed the maximum load capacity of 1 5 kg for each rotor position Always balance all tubes within 10g 5g When only one system is being used the acceptable max Out Of Balance OOB is 85g but when both systems are being used the acceptable max OOB per system is 65g Always locate tubes correctly in sample holders Always locate sample holders correctly in the rotor aperture Always load two or four swing
6. gt jejg ci 6 s 2 5 a gt o x Io lt D e gt bam O DIS Cis 3 a 5 w 2 0 5 2q a m sj nI L a T gt N oO N Those solvents with a Y in the Autoprogram Available column are available from the Solvent drop down list when setting up a run The solvents with an N against them will have to be entered using the Other option and the rest of the data entered manually Run No 91 Last Used Not yet used SOLVENT Run Data Protection Acetonitrile ACN Next Run Number 0 for none Ammonium Hydroxide NH30H Run Name Chloroform TCM Sample Holder Type Di Chloro Ethane DCE Sample Volume ml DCM Di Methyl Acetamide DMAc DMF IR Sensor Control Temperature C DMSO Ethanol EtOH CoolHeat Enable Pressure mbar Chamber Temperature Control C Rotor Speed Methanol MeOH NMP Heat Off Option Tri Ethyl Amine TEA Heat Off Elapsed Time HH MM TFA End of Run Option THF End of Run Elapsed Time HH MM Toluene PhMe End of Run Defrost and Drain Water H20 Pressure Control Regime BP lt 50 Final Controlled Pressure mbar BP gt 180 Other Clear Done GENEVAC LTD HELP TL ENTER to select deselect select Done when finished ESC to cancel 10 1562 Issue 1 Revision 10 September 2005 Page 8 of 47 Genevac HT 24 Series II Workstation 2 Safety and Maintenance Notes 2 1 Symbols The following safety symbols are used throughout this manual
7. 33 indicate the time left to End of Chamber Temperature C 40 R if linked End of Condenser Gas Temp C seat un or If unkea runs Ena O Pressure mbar 10 1 Stage spin Rate rpm 1494 Total 44 46 15 End of Run 64 43 18 Press the DISPLAY key during a Spiming run to return to the RUN LOG screen Pressure Spin Rate H mbar Operating the STOP key at any time during a run will terminate the run The chamber will vent and the rotor will start to spin down You will not be able to open the chamber until the chamber has reached atmospheric pressure and the rotor has stopped oo 40 00 45 spinning Post Run Final Drying Period When the chamber has vented and the rotor stopped you will be given this STATUS prompt 0 1562 Issue 1 Revision 10 September 2005 Page 29 47 SampleGuard With an evaporator with SampleGuard fitted the top left hand section displays the current temperatures of channels 1 and 2 the chamber temperature the condenser temperature the chamber pressure the total time elapsed and the stage time elapsed if linked runs are being undertaken RUN 91 Example Channel 1 Temperature C Channel 2 Temperature C Chamber Tenperature C Condenser Gas Temp C Pressure mbar Spin Rate rpn Total 66 63 44 This Spinning COO Litt Evaporating RUN 91 Channel 1 Temperature C Channel 2 Temperature C Chamber Temperature C Condenser G
8. 91 Last Used Not yet used Next Run Number 0 for none Run Name sample Holder Type sample Volume ml IR Sensor Control Temperature C CoolHeat Enable Pressure mbar Chamber Temperature Control C Rotor Speed Heat Off Option Heat Off Elapsed Time HH MM End of Run Option End of Kun Elapsed Time HH MM End of Run Defrost and Drain Pressure Control Regime Final Controlled Pressure mbar GENEVAC LTD SOLVENT Acetonitrile ACH Ammonium Hydroxide CNH3SOH Chloroform TCM Di Chloro Ethane DCE DCM Di Methyl Acetamide DMAc DMF DrSo Ethanol EtOH Ethyl Acetate EtAc Hexane Hex Methanol MeOH NMP Tri Ethyl Amine TEA Toluene PhMe Water CH2Z0 BP lt 50 BP 180 Other Clear Done TLYENTER to select deselect select Done when finished ESC to cancel HELP EtAc Hex Solvent When you select this field you are given a list of solvent types that have already been programmed into the evaporator Use cursor keys to move up and down Press ENTER key to select Highlighted in blue Please note that the solvent s that you have selected from the menu appear in the bottom left corner of the screen when Select Done finished Once your selection has been made you are now given an option to Auto Program the remaining run parameters Run No 91 Last Used Not yet used SOLVENT Run Data Protection Next Run Number
9. Yes this setting protects the run data from inadvertent corruption Password prevents others from editing your run requirements Press the ENTER key to toggle between Yes No and Password Note that you will not be able to make amendments or additions if the data is locked Lock the data after completing the run entry This control enables you to link and loop runs in any sequence If you want to link runs list the number of the run you want to follow the run you are entering Repeat this process for any subsequent runs you would like to link You can also loop a run The limitation of how many runs you can link will be either the maximum run time of 99 hours 59 minutes or 99 different steps Linked and looped runs can always be interrupted by manually stopping the system Use the DOWN cursor key to move to the next field Enter the title of the run that should be no more than 20 characters long Use the DOWN cursor key to move to the next field Press ENTER to display the Select Sample Holder drop down menu Use the UP and DOWN cursor keys to select the option and press ENTER If OTHER is selected the description should be no more than 20 characters long Press ENTER and input the volume in mls Press ENTER to display the Solvent Drop down menu Use the UP and DOWN cursor keys to select the option s and press ENTER Once your selection has been made select Done and press Enter you are now given a ne
10. a venting procedure linked to the end of the evaporation process to help remove residual vapours from the chamber When using these preset programs they will only function correctly if Sample Guard probe 1 is placed into the aluminium sample holder block or fast stack swing BP Range Solvent Examples Application 60 90 C Ethyl Acetate or Methanol Single volatile solvents with no risk of bumping 40 90 C IDCM Methylene Chloride Volatile solvent mixtures and DCM or Chloroform Methylene chloride where risk of bumping is high Medium BP Solvents 90 155 C DMF or Toluene Medium bp solvent or mixture of medium bp solvents Med BP amp Volatile 40 155 C DMF amp DCM Methylene Mixtures of medium and volatile Chloride solvents with high risk of bumping No solvents should be Rapid pre heat of chamber before a present high bp solvent run swings and samples MUST be removed before this method is used High bp 140 140 190 C DMF DMAc DMSO High bp solvents 190 C Very high bp solvents HPLC Fractions Water amp Acetonitrile or HPLC fractions Methanol Aqueous only 100 C mee Any Drying samples which have not been fully dried using another method The condenser MUST be empty before this method is used 10 1562 Issue 1 Revision 10 September 2005 Page 21 of 47 Each line on the SELECT RUN screen is generated from the RU
11. maintenance schedule to be adhered to as detailed in operator s manual Warranty does not cover accidental damage misuse modifications or inappropriate repair by untrained personnel Warranty does not cover consumable items Failure to adhere to the above would result in the costs of repairs being charged Consumable Items Sample Guard thermocouple probes Cole Vacuum Pump oil Control fuses 10 1562 Issue 1 Revision 10 September 2005 Page 46 of 47 Genevac HT 24 Series II Workstation 11 Useful information Genevac Limited If you need to contact Genevac for assistance use The Sovereign Centre either the telephone or fax Hotlines given Farthing Road Ipswich It will always help Genevac Service if you have the IP1 5AP serial numbers at hand for the components of your system United Kingdom a If you need to contact Genevac Sales for information Sales and Service Hotlines on Service Contracts or products use the telephone or fax Hotlines given Service Hotline 44 0 1473 243000 Alternatively Email or visit our web site Sales Hotline 44 0 1473 240000 Fax 44 0 1473 461176 Email mailto salesinfo genevac co uk Web site http www genevac com Genevac Inc 707 Executive Boulevard Suite D Valley Cottage New York 10989 United States of America Sales and Service Hotline 1 845 267 2211 Fax 1 845 267 2212 Email atlas genevacusa com 10 1562 Issue 1 Revision 10 September 200
12. solid state case heaters and Coolheat radiant lamps to heat the chamber and samples The control of chamber swing and sample temperature vacuum ramping rate chamber pressure rotor speed is handled by an embedded PC IR Infra Red Sensor Non contact temperature measuring is fitted as standard The end user has the facility to auto program run parameters for any recognised solvent mixture entered These optimised run parameters are highlighted in WMA on the display screen when this Auto Program facility has been selected Recognised Solvent s available from drop down menu Sample Holder type available from drop down menu Lyophilisation Freeze Drying available as a Rotor Speed selection on evaporators equipped for this configuration i Please note Lyophilisation samples are to be frozen prior to being placed in evaporator End of Run Prediction only available with SampleGuard 1 Heat Flow 2 Sample Detection The Run Progress screen has a fully featured graphical display providing annotated plots for temperature and pressure now a log scale The control software enables the user to specify and store a library of up to 100 different evaporation profiles in an uncomplicated manner Run profiles can also be linked to provide multi stage runs Up to 100 different profile steps can be linked and iterative loops can also be programmed With a maximum single run time of just below 100 hours the system is extremely flexi
13. then you will get a warning on the screen You can also set the automatic End of Run Defrost and Drain option here Only available between linked runs and is typically used to remove mixed solvents After setting the values save the Run and continue Page 24 of 47 Genevac HT 24 Series II Workstation Run Mo 91 Last Used 14 04 14 07 05 SOLVENT Run Data Protection Acetonitrile ACH Next Run Number for none Ammonium Hydroxide CNH30H If you did not select Run Name Chloroform TCM Auto Program or were sample Holder Type Di Chloro Ethane DCE not given the option sample Volume ml due to inputting an Solvent unrecognised solvent IR Sensor Control Temper then you will be CoolHeat Enable Pressure presented with this Chamber Temperature Cont screen Rotor Speed NMP Heat Off Option Tri Ethyl Amine TEA If editing an existing run Heat Off Elapsed Time HH MM TFA parameters will remain End of Run Option THF as previous settings End of Run Elapsed Time HH MM Toluene Phe End of Run Defrost and Drain Water CH20 Pressure Control Regime BF lt 50 If creating a new run Controlled Pressure mbar BP gt 180 parameters will be set to Other safe default settings Clear GENEVAC LTD HELF tLENTER to select deselect select Done when finished ESC to cancel IR Sensor Control Run No 91 Last Used 14 47 14707703 Last Changed 14 47 147 07 03 Temperature Run Data Prot
14. 5 Page 47 of 47
15. CTION MAINTENANCE OPERATOR CONTROLS Only in exceptional circumstances OPTIONS under guidance from Genevac will MAINTENANCE non qualified personnel be required to use this option e In MAINTENANCE you can write the machine settings to file e Press ESC to leave this menu GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Modify evaporator configuration etc Use the cursor keys to select MAINTENANCE and press ENTER RITE MACHINE SETTINGS TO SIMUL INI e Use the ENTER key to write the machine settings to the file SIMUL INI e Press ESC to exit this screen GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Writes current machine settings for use in simulation mode 7 a O 562 Issue 1 Revision 10 September Page AT USER MENU LAMP LAYER SELECTION STATUS OPERATOR CONTROLS Not required under normal OPTIONS conditions This option displays Ma INTENANCE information useful to Genevac STATS personnel in resolving technical issues e In STATUS you can write the machine settings to file e Press ESC to leave this menu GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Show evaporator status variables flags valve states etc Use the cursor keys to select STATUS REA ROSE and press ENTER SENSORS FLAGS VALUES Pressure 935 6 ChamberHeatEnab led No Iso Closed
16. EE eia 18 5 1 Checks prior to DOWER Up srira Eae aE 18 5 2 How to switch on the evaporator Ss cccccccccsececeeeeceeeeceeeeeseeeeeeeeeseeeeseueesseeeeeeeessueesseeesaees 18 59 USING TING KEV OO sci ncecruvenenivandedudicanbiauicnstvnidnaudicunvenswinandvasddaalenshatwnteaudnaaneaulennmteaninautnedincaunabi 19 5 4 What the screens dO cccc cece cece eccseceeceeceeeeeceeececeececeeseesaeeseeseeceeseseeeaeeseeeuecseseeseesseeseesaes 20 Pre programmed RUNS seriene ia eaaa eaaa iaaa eiaa 20 Sample Holder Type siseses nT E E A EEEE NEE A ENE iE 22 SIMPE VOE a A E E E ee ee en eee eer eee ee eee 22 SEE Ae een E E E A E E E ET E EE E EEE A E ee ne ee 23 IR Sensor Control Temperature ccccceccsccceecceeeceueceueeceeccaueecueeceesaeeseusecaessueesseessusenaes 25 SampleGuard Control Temperature c cece cecececcceeee cece eeseeeseeeeseeeeeeeseeesaeesaeeeeeeeseeeseeees 26 SampleGuard Control Channel ccccccceeecceeeceeeeseeeseeeeeeeseeeeseeeseeeseeeseeeeseeeseeeeseeeseeeseeees 26 COOINEEEENADIG PICSSUNS sirsiran dimtatacimwadniadeiaamneqeaee EEA 26 Chamber Temperature Control ccccccccsecceeeceeeeeceeeseeeeeeeseeeeseeeseeeeeeesseeeseeseeeseeeeseeegeeees 26 ROO ODOGUN sabres edocs eae a jeea oad co sand caasedeean deameeneageaneteaeaeucaeeus 27 Bote ODNO e E antennae eae at reer to tere nero er oe me ee ees ae ee aera cee ae 27 D A A e E E E 28 FO EIM OOTUS eree e E E 28
17. GENCY STOP BUTTON IS NOT TO BE USED TO SHUT DOWN THE SYSTEMS ON A ROUTINE BASIS 10 1562 Issue 1 Revision 10 September 2005 Page 6 of 47 Genevac HT 24 Series II Workstation Details Continued HT 24 Rear View Fume Hood rear panel removed for clarity Data Connections x 2 Mains Power Supply Connections x 3 amp Waste Solvent Pump amp Electrical Circuit Breakers 10 1562 Issue 1 Revision 10 September 2005 Page 7 of 47 Genevac HT 24 Series II Workstation List of Solvents Autoprogram Solvent Density g cm Density Temp C Alabi N Acetic Acid 1 05 0 79 NO RN RD S 1 48 1 24 1 33 ide DMAc 0 94 ine DMA 0 68 0 94 1 10 0 79 NINININININIJIN O O Aal lo os o o N 0 65 0 79 MeOH 0 79 1 02 Pyridine 0 98 0 89 NIN OJo cet AK NO NO On lt lt r j lt lt o Q O gt D ai Z Z U NIN Olo N N AN HCI Thionyl Chloride or Di Ethyl Ether compatibilities are not available Genevac and the ATEX Directive Please note that it remains the responsibility of the user to consider any solvents being evaporated within the context of the ATEX directive The presence of solvents on the list above indicates only that they will not damage the system If further information is required please contact your Sales Representative or visit http www genevac com THA eee gaaja z
18. Genevac HT 24 Series II Workstation High Throughput Evaporator T 24 Evaporation pure and simple _ _ User Manual Issue 1 Revision 10 September 2005 Part Number 10 1562 Genevac HT 24 Series II Workstation Contents Amendment Contool FON cssriin enn save tamaaadatestnsay cava daysunsoanwniaph savannas iqussaumeantentabaioteacduneaneeemacimaiens 3 1 MOGUC IO e E E E oeseun ata acneae 4 BTS oases cee a E E E E E tease aecacsea see auenaeaerean 5 LIST OF SOIVENIS nenie E E AEE SS 8 2 Safety and Maintenance Notes ccccccccscccsecceeecceeceueeceueceeeceueecseesaeeseessueeseeesueesaeecseesseessaeesaaeess 9 2d VOO e E E E neste esencnace cnc tseaseteGseenee 9 A S a E E E E N 9 3 System description and ODUOMS xia cescoctcecccecsccecnseceeincteihedasetonitactestioddeasedanianiaussepdedaadectdeexaeenadasosiaceis 11 3 1 Scope of delivery and installation cc ceeccccceceeeceeeeeeeeseeeeeeeeseeeseeeseeeeseeeseeeseueeseeeseeesanes 13 3 2 Checking the CeliVEry ccccccccccccceeccececneceeeceueceeeceecaeesaeeesaeesueeseuecaeesaueesueesueeseeeseeesaaees 13 39 Arangino COMMISSIONING sassen ena canst cuseecataniguannescsnaueundsacnedeaevecen ae a 13 E E a o A T E EN E E T ATE EE E ET 13 3 5 Positioning CY AON AIO Masco Scere tanec cndtesentemecenteedte ance nastue sc andcentgeredeenasewae seed send enueemiesieeets 13 4 Safe loading of rotor Ge
19. IR SENSOR 10 1562 Issue 1 Revision 10 September 2005 This MUST be used to control the sample holder or swing temperature Either channel 1 or channel 2 may be used ensure that the channel chosen is selected as the control channel in the run options Automatically detects dryness by monitoring the rate at which the solvent is evaporating Low solvent loading or if the lamps are turned off may cause Heat Flow to fail If failure occurs select one of the other two options For very low solvent loading requiring very little heat then the following would be used Requires both SampleGuard probes Channel 1 to monitor the swing holder temperature and Channel 2 in the centre well of the sample holder to monitor sample temperature Monitors the temperature difference between the 2 channels When the temperature difference reaches the preset figure Not user configured the run is terminated Page 40 of 47 Genevac HT 24 Series II Workstation Heat Off Elapsed Time End of Run Option End of Run Elapsed Time End of Run Defrost and Drain Pressure Control Regime Full Vacuum Controlled Pressure NOT AVAILABLE FOR LYOPHILISATION Variable Dri Pure NOT AVAILABLE FOR LYOPHILISATION 10 1562 Issue 1 Revision 10 September 2005 This can be in a range of O lamps off for the entire run to 99 hours 59 minutes This option is the elapsed time after which the run will be stopped Press ENTER and in
20. L for none Run Name sample Holder Type sample Volume ml Bo lvent IK Sensor Control Temper CoolHeat Enable Pressure Chamber Temperature Cont Rotor Speed Heat Off Option AUTO PROGRAM Auto Programme Acetonitrile ACH Ammonium Hydroxide CNH3O0H Chloroform TCM Di Chloro Ethane DCE hyl Acetamide DMAc remaining parameters Yes l Nlol Heat Off Elapsed Time HH MM End of Run Option End of Kun Elapsed Time HH MM End of Run Defrost and Drain Pressure Control Regime Final Controlled Pressure mbar GENEUAC LTD HELP ol CEtOH Acetate EtAc Hex Methanol MeOH NMP Tri Ethyl Amine TEA TFA THF Toluene PhMe Water H2Z0 BP lt 50 BP 180 Other Clear TLYENTER to select deselect select Done when finished ESC to cancel EtAc Hex Press Y to accept Auto Program If you have entered an unrecognised solvent by selecting Other from the solvent menu you will not be presented with the option to Auto Program REFER TO THE TABLE ON PAGE 8 FOR THE SOLVENTS THAT HAVE BEEN CLEARED FOR USE IN AN HT 24 HCI Thionyl Chloride Or Di Ethyl Ether Compatibilities Are Not Available 962 Issue 1 Revision 10 September 2005 Genevac HT 24 Series II Workstation Run No 91 Last Used 14 04 14 07 03 Last Changed 14 06 147 07 03 Run Data Protection No Next Run Number 0 for none 0 Run Name Example Sample Holder Type Deep We
21. N DATA screen When the chamber is vented and the rotor stationary this screen is accessed by selecting EDIT at the foot of the SELECT RUN screen and pressing START When the system is running the RUN DATA screen can be accessed directly by pressing the SETTINGS key SETTINGS Run No 91 Last Used Not yet used Last Changed New entry Run Data Protection Next Run Number 0 for none Run Name sample Holder Type sample Volume ml solvent IR Sensor Control Temperature C CoolHeat Enable Pressure mbar Chamber Temperature Control C Rotor Speed Heat Off Option Heat Off Elapsed Time HH MM End of Run Option End of Run Elapsed Time HH MM End of Run Defrost and Drain Pressure Control Regime Final Controlled Pressure mbar GENEVAC LTD HELP Tl to select ENTER to edit MENU ESC to exit select level of Run Data protection No oO 0 0 20 100 Wait to cool to 20 High Elapsed Time 00 00 Elapsed Time 00 00 No Dr i Pure 0 0 Use the UP and DOWN cursor keys to move between fields Press ENTER to open a field make the entry and press ENTER again to close the field During a run you access this screen by pressing the SETTINGS key You can edit any parameter during a run in this way You can set Run Data Protection to protect your data see below Toggle between Yes No and Password Password requires you entering a personal 4 digit
22. alancing of swings and sample holders Opposite pairs of swings need to be balanced within specification and that the swings are of the same type and version Please note that there are several versions of Side Bridge Swings in circulation with a static weight ranging from 375g to 445g Ensure that swings of the same static weight are positioned diametrically opposite in the rotor ideally use the same version of swings in all four position of each rotor Genevac systems have some inbuilt tolerance for imbalance and a system for shutting off if the out of balance is unacceptably high but it is advised that the user aims for no more than 10g imbalance between opposite pairs of swings Where it is necessary to make dummy samples to balance real loads the balancing load should be of a similar solvent composition For example do not balance 200g of 50 50 Water Acetonitrile with 200g of water because partway through the run when the acetonitrile has all gone but the water has barely started evaporating the system would be 100g imbalanced Note that with a system such as the Fast Stack swing balancing is slightly more complex Suppose a Fast Stack Deepwell swing is used with two 96 well microtitre plates 2ml per well The Fast Stack swing is illustrated on the first page of this document In one swing the lower microtitre plate is empty the upper microtitre plate is full 1 8mls per well On the other swing the reverse is t
23. ange of 5 400 mbar Chamber Temperature Control There are 3 options available Wait for Chamber to Heat Range from 0 C to 45 C Wait for Chamber to Cool Range from 0 C to 45 C Automatic Control Temperature Is automatically set to an optimised figure for the recognised solvent mixture selected 562 Issue 1 Revision 10 September 2005 Run No 91 Last Used 12 45 03703703 L Run Data Locked Next Run Number for none Run Name Sanple Holder Type Lou sample Volume ml High 50 luent Lyophi lise ROTOR SPEED Select Lamp On Ratio SanpleGuard Control Temperature C SsanpleGuard Control Channel CoolHeat Enable Pressure mbar Chamber Temperature Control C AUTO Cool to 32 Control at 20 Rotor Speed Low Heat Off Option Heat Off Threshold End of Run Option Not Applicable End of Run Threshold Not Applicable End of Run Defrost and Drain Yes Pressure Control Regime Controlled Pressure Controlled Pressure mbar 10 Heat Flow Not Applicable GENEVAC LTD HELP TL to select ENTER to accept ESC to cancel Rotor Speed Low Run No 91 Last Used 14 40 03 03 03 Last Changed 12 35 03 03 03 Run Data Locked No Next Run Number 0 for none Run Name Example sanple Holder Type Deep Well Plate sample Volume ml 0 70 50 luent EtAc Hex sanp
24. as Temp C Pressure mbar Spin Rate rpn Total 99 45 43 End of Run 46 82 32 Spinning 00 40 Post Run Final Drying Period ALARMS ALARMS 00 45 mbar 1000 500 100 e The RUN LOG screen displays the real time events e The top left block gives current values e The top right block displays any alarms e The block at the foot of the screen displays the current status of the system and Instructions e Pressure is plotted on log scale e Press STOP to terminate a run at any time When run enters final drying period the display changes to indicate the time left to End of Run or if linked runs End of Stage Press the DISPLAY key during a run to return to the RUN LOG screen Operating the STOP key at any time during a run will terminate the run The chamber will vent and the rotor will start to spin down You will not be able to open the chamber until the chamber has reached atmospheric pressure and the rotor has stopped spinning When the chamber has vented and the rotor stopped you will be given this STATUS prompt 562 Issue 1 Revision 10 September 2005 Page 30 of RUH 91 Channel 1 Temperature C Chanel 2 Temperature C Chanber Temperature L C Condenser Gas Temp LC Pressure Cmbar Spin Rate Lrpn Total 44 48 15 Channel 2 OO 40 Exanp le End of Ru
25. be vial or flask formats Where no holder is available custom units can be made In a few cases worldwide users have developed their own holders and have collaborated with the Genevac R amp D department to ensure the holders are suitable and approved for use Important properties for a sample holder include Mass within prescribed maximum limit Closely matched mass within a set of holders Correct centre of gravity Good thermal conductivity Correct hole form and size tolerance to prevent tube or vial breakage under centrifugal force For correct use of Sample Guard Probes refer to SampleGuard Probe Positions document available at http www genevac com applications downloads1 html All Genevac holders are designed with these constraints in mind Other 3 party accessories may not be Generally apart from microtitre plates users are advised not to load non Genevac holders into a system without first checking with Genevac It is important that the swings and holders used are suitable for the Genevac system in use For example there are some sample holders on sale for the Series Il system that might appear to fit in a Series system but which would exceed the weight limitations See next section If in doubt always ask Genevac before running the system 10 1562 Issue 1 Revision 10 September 2005 Page 14 of 47 Genevac HT 24 Series II Workstation There are also instances where a sample holder which is perfectly sati
26. ble to meet every requirement Options Available options include Bump protection Dri Pure on one or both evaporators SampleGuard on one or both evaporators Extra powerful Coolheat lamps on one or both evaporators Low UV lamp lenses on one or both evaporators not available with high power lamps Built in fume extraction hood and pipe system Manual Condenser flushing Data Logging is available independently from each evaporator Dependent on user hardware both evaporators could be logged to the same PC The easy to use package provides the data needed for process and quality control conveniently and efficiently Hardware Required PC running Windows 95 98 NT 2000 or XP Around 5Mbytes of free space on your hard drive Serial Port on PC or USB to Serial Adapter Serial Cable to connect the PC to the Evaporator Contact your sales representative for purchase and installation details 10 1562 Issue 1 Revision 10 September 2005 Page 12 of 47 Genevac HT 24 Series II Workstation 3 1 Scope of delivery and installation Your HT 24 system has to be commissioned by Genevac personnel On delivery it is advisable to unpack your system at the point of receipt to ease the movement of the component parts to the point of use 3 2 Checking the delivery Check the contents of the delivery as soon as possible against the delivery note and notify Genevac Ltd immediately of any missing or damaged parts Refer to sec
27. code If you forget your password DataLogger can retrieve the run details including your password There are no password requirements when using DataLogger existing password protected runs can be overwritten Run No 91 Last Used Not yet used Last Changed New entry Run Data Protection Next Run Number 0 for none Run Name ample Holder Type sample Volume ml Solvent IR Sensor Control Temperature C CoolHeat Enable Pressure mbar Chamber Temperature Control C Rotor Speed Heat Off Option Heat Off Elapsed Time HH MM End of Run Option End of Run Elapsed Time HH MM End of Run Defrost and Drain Pressure Control Regime Final Controlled Pressure mbar GENEVAC LTD HELP Tl to select ENTER to accept ESC to cancel Deep Well Plate SAMPLE HOLDER select Sample Holder Microtitre Plate Deep Well Plate Tube Uial Holder Other High Elapsed Time 00 00 Elapsed Time 00 00 No Dr i Pure 0 0 Sample Holder Type When selected you are presented with the SAMPLE HOLDER menu Use Cursor keys to move up and down Press ENTER to select Select your sample holder type or if not defined select Other and enter the details Sample Volume Select and enter value s 562 Issue 1 Revision 10 September 2005 U Q O No NI O e Run Mo Run Data Protection
28. creen is accessed or user input data is required The START and STOP keys start and stop a selected run The cursor direction keys move you around the screen in the direction of the arrows The ENTER key is used to open and close a field on the Run Data screen when inputting or amending data Note that the START key also acts as an ENTER key when the keyboard is not illuminated Operating the MENU key displays the USER MENU screen only when the rotor is not spinning and the chamber is vented Operating the DISPLAY key displays the RUN LOG screen only when a run is in progress or has finished Operating the SETTINGS key displays the RUN DATA screen only for the selected run Note that the RUN DATA screen can also be accessed from the menu VIEW EDIT DETAILS option on the SELECT RUN screen when a run is not in progress The following notes describe the function of each screen and provide an explanation of the prompts displayed Page 19 of 47 Genevac HT 24 Series II Workstation 5 4 What the screens do There are three main control screens The SELECT RUN screen lists the library of evaporation run profiles you can choose This screen has the capacity to store 100 different run profiles from which you can select a particular run or set of runs The screen is accessed after switching on the pump and evaporator and by pressing the START key on the keyboard e You store and select your runs on these scree
29. d input the pressure below which you want the lamps to be turned on This can be in the range of 5 400 mbar If nothing is selected the setting will default to 400 mbar Note this is not available for Lyophilisation Press ENTER and Select the method from the 3 options displayed Wait for Chamber to Heat Range from 0 C to 45 C Wait for Chamber to Cool Range from 0 C to 45 C Automatic Control Temperature is automatically set to an optimised figure for the recognised solvent mixture selected Input the minimum temperature you want the chamber to reach before spin up will commence Page 39 of 47 Genevac HT 24 Series II Workstation Rotor Speed Heat Off Option ONLY ELAPSED TIME IS AVAILABLE WITH IR SENSOR Press ENTER to display the Select Rotor Speed drop down menu Use the UP and DOWN cursor keys to select Low or High or Lyophilise optional at order Low speed applies nominally 300 G and high speed nominally 500 G Lyophilise applies nominally 50 G at a very low rotor speed Selecting the Dri Pure option described later will over ride this option and sets it to High If nothing is selected the setting will default to LOW speed Select either Elapsed Time Heat Flow or Sample Detection For Elapsed Time enter value in hours and or minutes NOT AVAILABLE WITH IR SENSOR NOTE Control Channel Probe MUST be placed in the swing or sample holder Sample Detection NOT AVAILABLE WITH
30. ection No Next Run Number 0 for none 0 Run Name Examp le If you have an IR sample Holder Type Deep Well Plate Sensor you must set IR sample Volume ml 0 7 50 lvent EtAac Hex Sensor Control Temperature within the IR Sensor Control Temperature C 4 range of 20 to 70 C CoolHeat Enable Pressure mbar 200 Chamber Temperature Control C AUTO Cool to 32 Control at 20 Rotor Speed Low If your evaporator is fitted with Heat Off Option Elapsed Time S leG d th hi Heat Off Elapsed Time HH MM 00 00 ampleGuard then this End of Run Option Elapsed Time option will not be End of Run Elapsed Time HH MM 60 00 available but 2 other End of Run Defrost and Drain Yes Pressure Control Regime Controlled Pressure options SampleGuard Controlled Pressure mbar 9 5 Control Temperature and SampleGuard Control Channel will GENEVAC LTD be HELP TL to select ENTER to edit MENU ESC to exit 10 1562 Issue 1 Revision 10 September 2005 Page 25 of 47 Run No Run Data Protection Next Run Number Q for none Run Name sample Holder Type sample Volume ml 50 lvent SampleGuard Control Temperature C SsampleGuard Control Channel CoolHeat Enable Pressure mbar Chamber Temperature Control C Rotor Speed Heat Off Option Heat Off Threshold End of Run Option End of Run Threshold End of Run Defrost and Drain Pressure Control Regime Controlled P
31. elow l P 2 5 Limitations of use Your evaporating system is unsuitable for use under the following circumstances e With strong mineral acids such as HCI and HBr at all concentrations e For use as a pressure vessel 10 1562 Issue 1 Revision 10 September 2005 Page 10 of 47 Genevac HT 24 Series II Workstation 3 System description and options The HT 24 is a simple large capacity stand alone space saving machine centred around two HT 12 or HT 8 Series Il evaporators mounted on a small footprint trolley Each evaporator maintains its normal capability remote control and data logging but gives faster processing by allowing independent operation It is easy to use reliable robust and safe The HT 24 gives the user the option of simultaneously evaporating 2 different solvents providing they re not reactive Other system features are sample integrity rapid defrosting and pullout sample shelves for loading unloading evaporators Pullout sample shelves A single scroll pump is shared between the 2 evaporators by means of a vacuum manifold which using smart technology intelligently switches the pump to each evaporator as required The pump is a dry vacuum pump compact in size driven directly by a single phase electric motor and air cooled Either evaporator can run independently or both evaporators can run together Processing can be staggered one unit working the other being emptied filled Si
32. hout notice No part of these instructions may be reproduced in any form or be processed duplicated or distributed by electronic or optical means without the written permission of Genevac Limited All rights reserved Genevac Limited These operating instructions should be read before you use the Genevac HT 24 Evaporating System Keep them near the system for easy reference Your attention is drawn in particular to Paragraph 2 Safety and Maintenance Notes 10 1562 Issue 1 Revision 10 September 2005 Page 3 of 47 Genevac HT 24 Series II Workstation 1 Introduction Drawing on extensive experience in the drug discovery field the HT 24 Workstation is designed to provide very high performance coupled with ease of use occupying the minimum of laboratory space The HT 24 comprises a Workstation Trolley complete with 2 condensers 1 for each evaporator a Scroll Pump and an 11 litre Solvent Waste Container The HT 24 can accommodate 2 x HT 8 or 2 x HT 12 Series Il evaporators or a combination of both although it can also be used with a single evaporator installed at either position Position 1 is the left hand position viewed from the front The status of each individual evaporator is displayed and controlled on a single keypad display module indicating the run time the vacuum rotor temperature and chamber temperature on digital displays SERIES SYSTEMI Simple to use up down controls enable the run time rotor and chamber tem
33. ing specifications BS EN ISO 12100 pts 1 amp 2 2003 Safety of Machinery Basic concepts general principles for design EN 60204 1 1998 Safety of machinery Electrical equipment of machines Pt 1 General Requirements EN 294 1992 Safety of machinery Safety distances to prevent danger zones being reached by the upper limbs EN1088 1996 Safety of machinery Interlocking devices associated with guards Principles of design and selection BS EN 61326 1998 A1 A2 Electrical Equipment for measurement Control and Laboratory use EMC Requirements BS EN 61000 3 2 2001 Electromagnetic compatibility EMC Limits Limits for harmonic current emissions equipment input current up to and including 16 A per phase BS EN 61000 3 3 1995 A1 A2 Electromagnetic compatibility EMC Limits Limitation of voltage fluctuations and flicker in low voltage supply systems for equipment with rated current lt 16 A BS EN 61010 1 1993 Safety requirements for electrical equipment for measurement control and laboratory use BS EN 61010 2 020 1995 Safety requirements for electrical equipment for measurement control and laboratory use Particular requirements for laboratory centrifuges 10 1562 Issue 1 Revision 10 September 2005 Note Under the Low Voltage Directive 73 23 EEC the limit for earth leakage current for Class1 portable equipment is specified at 3 5mA Whilst every effort has been taken to mini
34. ion 10 September 2005 Page 20 of 47 Genevac HT 24 Series II Workstation Pre programmed Runs SampleGuard option only Providing that your HT 24 has the SampleGuard option fitted to the chambers it will have been loaded with a number of pre programmed evaporation runs The runs can be found located at runs 51 to 60 of the RUN selection screen Desired runs can be copied to the top page so as to be readily available using the copy to function Methods 61 through to 98 are all associated with these pre programmed methods and methods 99 and 100 are for use by Genevac service engineers please do not alter them The pre programmed methods have been designed to cover a group of solvents such as high boiling point solvents The table below provides a guide to aid correct run selection Each method has been programmed to be used with a particular group of solvents therefore it may be possible to program a more efficient method for just one of those solvents If you regularly use a single solvent or solvent mixture then please contact your Genevac representative or applications genevac com for assistance programming a suitable method These methods have been designed to make use of all the appropriate features of the system to provide the most optimal evaporation conditions All methods make use of the automatic end of method detection feature so that no times need be set the system will stop when all the samples are dry Each method has
35. leGuard Control Temperatur HEAT OFF OPTION SanpleGuard Control Channel CoolHeat Enable Pressure mbar Select option for turning off CoolHeat Chamber Temperature Control Rotor Speed Elapsed Time eat Off Option anple Detection Heat Off Threshold End of Run Option End of Run Threshold End of Run Defrost and Drain Yes Pressure Control Regime Controlled Pressure Controlled Pressure mbar 10 GENEVAC LTD HELP TL to select ENTER to accept ESC to cancel switch CoolHeat off when Heat Flow drops below predetermined level ATTENTION THE 3 HEAT OFF OPTIONS ARE ONLY AVAILABLE IF YOUR EVAPORATOR HAS SAMPLEGUARD FITTED IF YOUR EVAPORATOR HAS IR SENSOR THEN ONLY ELAPSED TIME IS AVAILABLE Rotor Speed There are 3 options available Low Rotor speed applies nominally 300 G High Rotor speed applies nominally 500 G Lyophilise Rotor speed 500 rpm SampleGuard and Coolheat are not available Heat Off Option There are 3 options available Elapsed Time You must set the values for Heat Off Elapsed Time and End of Run Elapsed Time Heat Flow Automatically detects dryness by monitoring the rate at which the solvent is evaporating Low solvent loading or if the lamps are turned off may cause Heat Flow to fail If failure occurs select one of the other two options Sample Detection Monitors the temperature difference between the 2 SampleGua
36. ll Plate sample Volume ml 0 7 Solvent EtAc Hex IR Sensor Control Temperature C CoolHeat Enable Pressure mbar Chamber Temperature Control C Rotor Speed Heat Off Option Heat Off Elapsed Time HH MM End of Run Option End of Run Elapsed Time CHH MM End of Run Defrost and Drain Pressure Control Regime Controlled Pressure mbar GENEVAC LTD HELP tl to select ENTER to edit MENU ESC to exit Run No 91 Last Used 12 12 11707703 Last Changed 12 13 11 07 06 Run Data Protection No Next Run Number Q for none Run Name Example sample Holder Type Deep Well Plate 0 7 Etac Hex Heat Off Option Heat Off Elapsed Time HH MM End of Run Option End of Run Elapsed Time HH MM End of Run Defrost and Drain Pressure Control Regime Controlled Pressure Controlled Pressure mbar 4 5 GENEVAC LTD HELP TL to select ENTER to edit MENU ESC to exit an Select enter name of the solvent s Py ee i mh arrn oY ia S ma e EA fala wy e i A ie Lei anges on a Lr 10 1562 Issue 1 Revision 10 September 2005 With Auto Program Y es selected The screen will now display the Auto Programmed data in OVT Light Blue With IR Sensor Temperature Control only Elapsed Time is available as a Heat Off Option So you will need to manually enter the values for Heat Off Elapsed Time and End of Run Elapsed Time If you try to save the run without setting these values
37. mise the leakage current of the HT 24 it may slightly exceed this value at typically 4 6mA This is normal and does not indicate a problem with the system 9 Safety WARNING THIS SYSTEM MUST BE EARTHED THIS EVAPORATOR IS A SAFETY CLASS 1 PRODUCT ACCORDING TO IEC CLASSIFICATION IT MUST NEVER BE USED WITH ANY_INTERRUPTION TO THE SAFETY EARTH CONDUCTOR IT IS AN INSTALLATION CATEGORY II PRODUCT AND IS INTENDED TO OPERATE FROM A NORMAL SINGLE PHASE SUPPLY THIS EVAPORATOR HAS BEEN DESIGNED TO BE USED IN A POLLUTION DEGREE 1 ENVIRONMENT NO POLLUTION OR ONLY DRY NON CONDUCTIVE POLLUTION ANY MAINTENANCE OR_REPAIR_ OF THIS PRODUCT SHALL BE CARRIED OUT BY GENEVAC _PERSONNEL OR _ _ APPROVED REPRESENTATIVES OF GENEVAC USING ONLY APPROVED SPARE PARTS Page 45 of 47 Genevac HT 24 Series II Workstation 10 Warranty Statement This product is guaranteed for period of 12 months from the date of delivery to site In the unlikely event of any defect arising due to faulty materials or construction resulting in system failure the unit will be repaired free of charge This to include all labour and component costs incurred This warranty is subject to the following provisions 1 2 5 System must be sited installed and operated in accordance with operator instruction manual Unit only used for purpose it was sold and in accordance with Genevac published compatible solvent list Regular cleaning and preventative
38. multaneous extraction of different solvents is possible using both evaporators provided that these do not react with each other within the drain circuit and waste container The condensers are capable of chilling defrosting and draining independently using smart technology integrated with V2 01 software Automatic drain valves and drain pumps ensure that solvent is removed from the condenser pots This will only occur if the Waste Solvent Container that it is fitted to the system has free space available and that the door is shut A load cell monitors the level of fluid in the Waste Solvent Container When the predetermined weight is reached the Waste Full lamp on the HT 24 control panel will illuminate and will sound an audible alert The volume of waste solvent in the container varies upon the individual solvents used due to their specific gravity Emptying the waste solvent container couldn t be any easier just open the right hand corner door of the HT 24 Lift the container away from the HT 24 Extended hoses allow this press in the drain hose self sealing quick release clip and remove the drain hose adapter Remove the vent pipe and disconnect the Anti Static strap using the quick snap fitting Remove the cap and empty the container Refitting is the reverse Lm Waste Solvent Container Pump Drain Hose Removal 10 1562 Issue 1 Revision 10 September 2005 Page 11 of 47 Genevac HT 24 Series II Workstation The evaporators have
39. n 44 44 44 ALARHS Pressure sate Rate _ 00 45 00 50 Select Option or press STOP to skip to select next run Select the DRAIN or DEFROST OPERATIONS option using the numeric keys To access from the main menu select DRAIN or DEFROST and press ENTER WAR IABLES Condenser Defrost ing Drain Status Drain Closed Flush Valve Not Fitted Isolation Valve Closed Vent Valve Open Rotor stopped Chamber Heat orf Spin Rate rpm oO Pressure mbar 935 7 Chamber Temperature 12 Condenser Gas Temp 13 Condenser Core Temp 12 Defrost oo i Completed when ALARMS Elapsed Time Defrost Drain Done Press START to commence DEFROST sequence STOP to cancel Press START to commence operation With the DEFROST CYCLE highlighted press ENTER to start the defrost cycle This will automatically initiate defrosting Drain the condenser after every run and at the end of the day A defrosted and drained condenser will operate more efficiently Periodically check the level of solvent in the waste container The light on the main control panel will illuminate when the container is full Screens similar to this are also displayed for DRAIN and if fitted the FLUSH option Select option 1 Skip to select next run i Defrost and Drain must be carried out at least once a week to prevent pot freezing clogging aE Te
40. n of the vacuum ramp Final Controlled Pressure Page 41 of 47 Genevac HT 24 Series II Workstation 6 Trouble Shooting and Maintenance Information to be included when available 10 1562 Issue 1 Revision 10 September 2005 Page 42 of 47 Genevac HT 24 Series II Workstation 7 Technical data Mechanical Data Max rotor RPM Max rotor RPM DriPure Max G Drive system Operating imbalance IR lamp number evaporator Condenser Specification Temperature Main pot capacities Pump exhaust pot Chamber construction Condenser drain valve Rapid defrost Vacuum System Vacuum display Vacuum control Vacuum ramp DriPure SampleGuard system ultimate vacuum Auto vacuum vent valve Electrical UK and Europe USA Max power requirement peak 10 1562 Issue 1 Revision 10 September 2005 1300 1 5 1800 1 5 500 Direct Drive 85g maximum when 1 system is being used 65g maximum per system if both being used 4 HT 8 6 HT 12 45 C 6 litre 1 litre 316L stainless steel 316L Stainless steel PTFE Yes 0 1200 mbar automatic 0 mbar atmosphere Yes Optional Optional 0 4 mbar Yes 3 x 230Vac 10 50 Hz 1 phase Each supply not greater 13A 3 x Schuko for Europe including Switzerland Denmark amp China 3 x 208V ac 410 60Hz 1 phase Each supply not greater 15A Approx 6 5 kW with high power lamps 30Amps estimated Page 43 of 47 Genevac HT 24 Series II W
41. ndow in each side Fumes are extracted by connecting a suitable duct to the Exhaust Spigot in the roof of the fume hood from your extraction system A flow meter is located in the top right corner to monitor performance This manual will guide you through the start up requirements set up needs and operation of the system to facilitate the most efficient procedure to protect your product s integrity and to ensure optimum performance at all times 10 1562 Issue 1 Revision 10 September 2005 Page 4 of 47 Genevac HT 24 Series II Workstation Details High Throughput Evaporator l Evaporation pure and simple HT 24 Fitted with 2 x HT 12 Complete With Optional Fume Hood Front View Note 3 Sliding doors in fume hood for easy access Scroll Pump amp Catch Pot Control Panel Waste Solvent Container Door Open Door Open 10 1562 Issue 1 Revision 10 September 2005 Page 5 of 47 Genevac HT 24 Series II Workstation Details Continued OPEN CHAMBER 1 BUTTON Press to open chamber door on evaporator 1 OFF BUTTON Press to turn off HT 24 and evaporators EMERGENCY STOP Press to use Used in an emergency to isolate Mains Power to the HT 24 Control Panel WASTE FULL LED Illuminates when Waste Solvent Container is full OPEN CHAMBER 2 BUTTON Press to open chamber door on evaporator 2 ON BUTTON Press to turn on HT 24 and evaporators POWER ON LED llluminates when HT 24 is switched on THE EMER
42. neral Document ccc cececceseeeeceeeeceeeeeaeeecaeeeeseueesaesesaueeeeueeeaeeeeaenesaees 14 NOMIC TIC AU Sirs pests cc ecwssedulseatiendinew ooo ensietied ga acelntioateebaaed vedoieinnnudvcud ccnanoauseantenecbeGadabieteegdeosebtaneeenieees 14 Use of Correct Accessories ac siarssisiosuinydsininn visaaivisaniiasaulouintadadieustounedanetheguaivanedeuesuntonnwuiesawaseadak ound dsnileuxeabnogiis 14 PFROMICTE NCE 10 Mass LMM sis 2cc cnn cn ccotaccasss daateneconatanenssins dence EEA 15 Safe loading of sample holders into SWINS cccccseecceeeeeeeeeceeeeceeeeeeeueeeaueeseeeessueeeaaeeeaueesaeeesaaees 15 Incorrect Sample Holder TOTALS scieiaceecennsecedacdeehabesemiendsised ndnavecinseuadsined d caedsnpdiien hand ndaandbabennteanasebecasas 15 Correct Sample Holder well Seated ccccccccscccseccceecceeeceeeceuecceeesseeceueeseeesaeesaeeseeeseessueeseeegaes 15 Incorrect Sample Holder on edge Of SWING ccccseecccseeeceeeecaeeeeeeeeesueecaeeeeeeeeeseueesauseseeeeeaaeesees 15 Series VS Series I Swings ccccecccsssccceeeccesecceeeeceeceseeeessueeceueecseeeceuecseeeecsaeesegeessesessasessuseeeseass 16 Balancing of swings and Sample NOICESS ccccecccececeeecaeeeeeeeceeeceeeceeeeseeeseeessueeseeeseeeseeeseueeseeeaes 16 Good Procedural DIACUCES sci cesnises lt csicsudaunteds gana taeannaaanecaivaetnendeeadensaindenaaecniaaneaaeeaeeiaans 17 5 Getting Stared sssusa n E r ASSES E SAE SEAE E
43. ns SELECT RUN e Use the UP and No Name 50 l vent Uol Holder T DOWN cursor keys 1 Oligosynthesis Amnonia ml DEEP WE 35 to move between rofiles 2 Oligo Purification Hater ACH Oml DEEP WE 38 PUSS 3 PCR Purification Water ACN iml DEEP WE 38 By moving across the 4 RNA Purificati Hater 110ml 24 15 4 0 NONZONLA MEMU pals EARR AE i j using left and right 5 Oligo Production Aqueous Mixture dnl SA ml T 4a A cursor keys e Youcan START a run e You can VIEW and EDIT a profile CENEVAC L TD e You can CLEAR a profile START EDIT GRAPH CLEAR COPY TO DRAIN Wagi FLUSH OPTIONS HELP e You can COPY a Select Run with tl Menu tem with keys press START to execute profile Starts selected Run using paraneters stored e Start to DRAIN e Start to DEFROST e Start to FLUSH If Option Fitted e Adjust your OPTIONS The 100 profiles are shown on this and nine other screens The other screens can be accessed quickly by moving the cursor down to the last entry on the page and pressing the down cursor key This will take you to the last entry on the next page Alternatively use the up cursor key If the evaporator is left on the run select screen for 2 minutes or more then the following status message will appear across the bottom of the screen This informs you of the Status of the condenser for that particular evaporator useful where multi users are involved Any key press will clear this message 10 1562 Issue 1 Revis
44. orkstation Technical data Continued Fume Hood Extraction In flow velocity min Extraction pressure Dimensions 0 5 m s 25 50 Pa 1346 mm 1420 mm with fume hood 1467 mm side doors open 712 mm 817 mm with fume hood 1685 mm 1915 mm with fume hood 700 kg approx W100 REFERENCE EXHAUST SPIGOT Width Depth Height Weight REAR 467 REFERENCE 1420 REFERENCE F ae i Li uJ a co Lis Lad Le oS Lu Lil co Le Lol m fma _ cc t 150 REFERENCE n a flO REFERENCE L FRONT Operating Environment Typical location Atmospheric pressure Temperature Humidity Emissions Noise 10 1562 Issue 1 Revision 10 September 2005 HT synthesis or lab environment clean amp quiet in proximity of sensitive equipment 900 1200 mbar at sea level 750 1000 mbar at altitudes of 1600m 15 C to 30 C 35 70 rH Not exceeding 66dBA at one metre from the evaporator Measured during DEFROST and DRAIN cycle Page 44 of 47 Genevac HT 24 Series II Workstation 8 EC Declaration of Conformity We Genevac Limited Declare that this product HT 24 Series Il Workstation Conforms with the relevant Essential Health and Safety Requirements of the European Machinery Directive 89 392 EEC as amended by 91 368 EEC and 93 44 EEC The EMC Directive 89 336 EEC and the Low voltage Directive 73 23 EEC See note opposite Conformity is demonstrated by compliance with the follow
45. peratures to be set in an instant and single push buttons set the other functions Either evaporator can run independently or both evaporators can run together Processing can be staggered one unit working the other being emptied filled Simultaneous extraction of independent solvents is possible using both evaporators provided that these do not react within the drain circuit and waste container The condensers are capable of chilling defrosting and draining independently using smart technology integrated with V2 01 software A load cell monitors the level of fluid in the Waste Solvent Container When the predetermined weight is reached the Waste Full lamp on the HT 24 control panel will illuminate and an audible buzzer will sound The volume of waste solvent in the container varies upon the individual solvents used due to their specific gravity A static dissipating device is in contact with the waste container when it is fitted to the HT 24 The single scroll pump is shared between the 2 evaporators by means of a vacuum valve manifold which intelligently switches the pump to each evaporator Data Logging is available independently from each evaporator Dependent on user hardware both evaporators could be logged to the same PC A custom fume hood is available as an option providing a totally enclosed system This is fitted on top of the HT 24 There are 3 sliding transparent doors in the front for easy access to the evaporators and a wi
46. put the time after which you want the run to stop This can be in the range of 1 minute to 99 hours 59 minutes Press ENTER to toggle between Yes and No Only available between linked runs and is typically used to remove mixed solvents Press ENTER to display the Select Pressure Control Option drop down menu Use the Up Down cursor keys to select the pressure option required Full Vacuum will take the chamber pressure down to the vacuum capability of the pump When the Controlled Pressure option is selected the Controlled Pressure field will be displayed Move down to this field using the DOWN cursor key and press ENTER Input the pressure you want the chamber to be limited to in the range of 0 to 500 mbar DRI PURE reduces the vacuum over a predetermined period to 50 mbar then goes to the control pressure as set by the user This feature is particularly useful in preventing bumping the violent boiling of solvents resulting in solvents being expelled which is a source of cross contamination of samples Bumping can also cause products to be deposited on the glass lenses of the Coolheat lamps which eventually results in breakages Note that during the DRI PURE cycle which is approximately 40 minutes the Coolheat function will be disabled Variable Dri Pure allows the user the option to set 1 The pressure at which the vacuum ramp will start The pressure at which the vacuum ramp will end The total duratio
47. rd channels 562 Issue 1 Revision 10 September 2005 U Q Q N f N O Oo 5 5 Starting arun Select the run that you require from the list Select START from the menu and press START button You will get an advisory message as shown below This is can be turned off in the OPTIONS menu SELECT RUN Solvent Vol Holder T Nxt Om1 20 CHECK LIST Have you checked That you have samples on the top level That your samples are balanced to 109 Run will start automatically in 14 seconds Press START to start now ESC to abort STOP to shutdown any other key to cancel timer GENEVAC LTD MENU Jy EDIT GRAPH CLEAR COPY TO DRAIN DEFROST FLUSH OPTIONS After ensuring that you have satisfied the requirements Press START to continue or STOP to shutdown 5 6 Linked runs If you have used the Next Run option and set the End of Run Defrost and Drain option to Yes then the following message will be displayed at the bottom of the screen Note plot is paused during this time RUN 99 MAINTENANCE TEST 1 Swing Temperature C Chamber Temperature C Condenser Gas Temp C Pressure mbar 935 1 Spin Rate rpm 1359 Total 00 05 19 This Stage 00 05 01 Spin Rate 25 C 00 06 minutes 5 7 During a run The main section of the RUN LOG screen gives a graphical display of the real time changes in chamber pre
48. re correctly seated all swings are swinging freely Refer to SampleGuard Probe Positions document available at http www genevac com applications downloads1 html for correct use of Sample Guard Probes Misloading may result in damage to samples and the machine and could void the warranty 10 1562 Issue 1 Revision 10 September 2005 Page 17 of 47 Genevac HT 24 Series II Workstation 93 PURIFICATION 94 SOLID PHASE SYNTH 95 COMPOUND STORAGE 96 OLIGO SYNTHESIS 97 SOLUTION PHASE 1 98 SOLUTION PHASE 2 99 MAINTENANCE TEST 1 100 MAINTENANCE TEST 2 WATERNACETONITRILE TFANDCM DMSO WATERNAMMON HYDROID DMF DCMNMETHANOL GENEVAC LTD SAN EDIT GRAPH CLEAR COPY TO DRAIN Select Run with Tl Men Starts selec Run usi 10 1562 Issue 1 Revision 10 September 2005 u Item with gt keys ng parameters s DEFROST 10m 18 X 15 2ml DEEP WE Oml DEEP WE 1ml DEEP WE 10ml 24 X 15 1ml DEEP WE Oml FLUSH OPTIONS 5 Getting started The following notes describe the basic start up set up and run instructions for your HT 24 evaporating system 5 1 Checks prior to power up Ensure that Data cables are connected if required Ensure that the 3 mains leads are connected to the rear of the system Ensure mains supplies are switched on at source Ensure that each evaporator ON OFF switch is set to ON These can be permanently left ON as the HT 24 controls power distribution If alread
49. ressure mbar GENEVAC HELP TL to select ENTER to edit MENU ESC t Temperature to maintain using SampleGua Run No Run Data Locked Next Run Number 0 for none Run Hane Sanple Holder Type sanple Volume ml 50 lvent sanpleGuard Control Temperature SsanpleGuard Control Channel CoolHeat Enable Pressure mbar Sele Rotor Speed Wait Wait Heat Off Option Heat Off Threshold End of Run Option End of Run Threshold End of Run Defrost and Drain Pressure Control Regime Controlled Pressure mbar GENEVAC HELP Tl to select ENTER to accept ESC toc Chamber temperature controlled to suit 91 Last Used 14 47 14 07 03 Last Changed 14 47 14707703 No 0 Example Deep Well Plate 0 7 Etc Hex 4 1 200 AUTO Cool to 32 Control at 20 Low Heat Flow Not Applicable Not Applicable Not Applicable Yes Controlled Pressure 9 5 LTD o exit rd 91 Last Used 12 25 035703703 Last Changed 12 31 03703703 No 0 Exanple Deep Well Plate 0 70 Et c Hex CHAMBER TEMPERATURE ct Chamber Temp control regime for Chamber to Heat for Chamber to Cool Automatic Control Not Applicable Yes Controlled Pressure 10 LTD ancel selected solvent or mixture SampleGuard Control Temperature Set within the range of 20 to 70 C SampleGuard Control Channel Channel 1 in Swing or Sample Holder Channel 2 in Sample Coolheat Enable Pressure Set within the r
50. rightness and optimum screen viewing angle OPERATOR CONTROLS In OPERATOR CONTROLS you can adjust the screen brightness to suit your viewing angle You can turn the audible warning off or on Press ESC to leave this menu Use the cursor keys to select the OPERATOR CONTROLS and press ENTER Use the UP and DOWN cursor keys to adjust the screen brightness to suit your viewing angle Toggle the beep ON or OFF Press ESC to exit this screen 562 Issue 1 Revision 10 September 2005 USER MENU LAMP LAYER SELECTION OPTIONS OPERATOR CONTROLS OPTIONS e In OPTIONS you can Enable or MAINTENANCE Disable the Auto Shutdown STATUS function e You can disable the Pre run Checklist prompt screen e Press ESC to leave this menu GENEVAC LTD HELP TL to move to required option ENTER to select ESC to leave this menu Auto Shutdown Check List options etc Use the cursor keys to select the OPTIONS and press ENTER OPTIONS MENU Auto Shutdown Disabled Pre run Checklist Enabled Use the ENTER key to toggle between Enabled and Disabled Press ESC to exit this screen GENEVAC LTD HELP ENTER to toggle between enabled disabled ESC to leave this menu Automatically shutdown 30 mins after end of run iiS VaV i oe E JE ENa aga ww Wi Pv LAU E E THIS OPTION IS TO ONLY BE USED BY QUALIFIED ENGINEERS LAMP LAYER SELE
51. rue Swings are the same weight but not balanced Centre of mass is a different distance from the pivot in each case so when rotor reaches full speed and swings reach normal ruinning position the rotor will not be balanced The two swings now weigh the same but if placed opposite each other in a system would not be balanced because when the swings rotated to their operating attitude the centre of mass of one is at a different radius to that of the other This effect becomes very significant when balancing multi level swings in large Mega systems It is also preferable not to run with only two swings out of four present on any one level of the rotor If there are only two swings worth of samples you should still load swings and empty sample holders in the other positions This ensures the rotor is evenly loaded 10 1562 Issue 1 Revision 10 September 2005 Page 16 of 47 Genevac HT 24 Series II Workstation Good procedural practice Finally there are a few general rules for safe operation of a system Ensure only users familiar with all the issues outlined in this document are permitted to operate the equipment Only load swings and sample holders approved by Genevac System should be loaded and started by the same person Never leave system unevenly loaded and close the door Someone may start it Never start or restart a system without checking it is evenly loaded all sample holders a
52. s of the same type and version in opposite and balanced configurations For partially loaded holders evenly distribute tubes in sample holders Always rotate the rotor by hand after loading and check that all sample holders are correctly located before starting a run and before re starting an interrupted run Do not load tubes or vials into sample holders other than those types that have been approved by Genevac Ltd Do not use sample holders that have not been supplied with your system without consulting Genevac Service 10 1562 Issue 1 Revision 10 September 2005 Page 9 of 47 Genevac HT 24 Series II Workstation 2 4 Safe Door Operation The evaporator door is opened and closed manually but locked automatically by an electric actuator Close and hold the door firmly against the door seal and press and hold the Door Close switch A single audible beep indicates that the door is locked and it is safe to proceed A proximity switch will prevent the mechanism from locking if the door is not closed G a When opening or closing the Chamber doors please be aware that there is a possibility of the user trapping their hand between the Left Hand Chamber Door and the Fume Hood as detailed in the picture below Care should also be taken when closing the Fume Hood sliding doors that the Chamber Doors are closed first so as to reduce the chance of damage being done to both chamber control moulding and fume hood doors example photo b
53. sfactory for the tube or vial it is intended for becomes unsuitable if used with something else even though it might appear that the alternative tube fits O K The Genevac Accessories Brochure indicates for each holder the maximum tube length that the holder is designed to take and these limits should always be adhered to It is available from the website http www genevac com brochure GenevacAccessories pdf Similarly some sample holders are intended for use in a Side Bridge swing only not in an Open swing even though they might appear to fit in the latter The Accessories Brochure has a note For use in Side Bridge Swing by these items but if in doubt ask Genevac Some users wish to run Genevac systems using the Bohdan Miniblock system as their sample holder Please note some not all of this range of items significantly exceed the mass limitations of a Genevac system If you plan to use Bohdan Miniblocks in a Genevac system please contact Genevac for a list of the relevant weights Adherence to Mass Limit There is a maximum mass that can be loaded onto each position of a Genevac swung rotor this total includes The swing The sample holder The tubes or vials The sample solutions Under no circumstances should this be exceeded If in doubt what your combined mass total is load up a full swing and weigh it In most cases with normal solvent volumes any sample holder currently on sale from Genevac will fall within
54. ssure spin rate sample and sample holder temperatures During the initial pump down as solvent starts to evaporate you may notice that the pressure indicated on the graph fluctuates this is quite normal due to the way that the evaporators and the scroll pump interact When the pump switches between evaporators a slight pressure rise may occur during the 30 second wait period this is due to the evaporation of the solvent s IR Sensor With an evaporator with IR Sensor fitted the top left hand section displays the current sample temperature the chamber temperature the condenser temperature the chamber pressure the total time elapsed and the stage time elapsed if linked runs are being undertaken RUN 91 Example Swing Temperature C 39 Chamber Temperature C 40 Condenser Gas Temp G 19 The RUN LOG screen Pressure mbar 10 1 displays the real time Spin Rate rpm 1494 events Total 00 06 04 This Stage 00 06 04 Spinning e The top left block gives Pressure Spin Rate current values e The top right block displays any alarms e The block at the foot of the screen displays the current status of the system and Instructions e Pressure is plotted on log scale e Press STOP to terminate a Evaporating CoolHeat Off run at any time When run enters final drying RUN 91 Example ALARMS _ period the display changes to swing Temperature tel
55. the mass limit for a Series Il system Safe loading of sample holders into swings Applicable where both Series I and Series Il evaporators are being used within the same laboratory There are two ways that it is possible to misload a sample holder into a swing One shown below is to rotate the sample holder such that it rests on the edges of the swing See B a aes Seer z E Incorrect Sample Holder rotated Correct Sample Holder well seated Another mode of misloading is illustrated below MAX MASS FOR SERIES 1 900g Incorrect Sample Holder on edge of swing Correct Both these modes of misloading are possible with an older version of the Open or standard swing but are virtually impossible with the new design of swing all Series Il systems feature the new design of swing The following illustration shows the difference 10 1562 Issue 1 Revision 10 September 2005 Page 15 of 47 Genevac HT 24 Series II Workstation Series vs Series Il Swings The older Series design is easy to distinguish because the corners are not welded The newer Series II swing has angled sides that make the incorrect loading illustrated above virtually impossible Care still has to be taken though Series II It also has rounded and welded corners Genevac offer a low cost upgrade to any user who has the old type of swing and who wishes to avoid the possibility of this misloading ever occurring B
56. tion 10 for contact details 3 3 Arranging commissioning If your system is to be delivered separately to commissioning Genevac Ltd will contact you prior to the delivery to agree a date to commission your system 3 4 Training Commissioning will normally include training in the basic operation of the System Further in house training is recommended to fully exploit the flexibility of the system Contact your Sales Representative for details THE HT 24 EVAPORATOR MUST NOT BE OPERATED BY PERSONNEL WHO LACK THE TRAINING OR PROFESSIONAL EXPERIENCE TO COMPREHEND THE HAZARDS THAT CAN ARISE WHEN USING THE SYSTEM Personnel without such training require thorough instruction These operating instructions should form the basis of this instruction 3 5 Positioning the evaporator Refer to the Technical data for dimensions and Plan view drawing also refer to Pre Installation Document When in final position ALL four wheels must be lifted clear of the floor using the inbuilt jacks The back of the system may be placed against a wall but must have suitable space either side to permit the opening of the doors 10 1562 Issue 1 Revision 10 September 2005 Page 13 of 47 Genevac HT 24 Series II Workstation 4 Safe loading of rotor General Document Genevac are obliged to include the following information in its entirety irrespective of the system type As with a centrifuge a Genevac centrifugal evaporator must be loaded correctly to remo
57. ve risk of damage Failure to correctly load a system can lead to loss of samples system damage and significant downtime This guide is intended for new users and also as a reminder for more experienced users The principles outlined apply to all Genevac evaporators The document deals with various aspects of loading Use of correct swings and sample holders Observation of weight limits Safe loading of sample holders into swings Balancing of swings and sample holders Good procedural practice Nomenclature Firstly it is important to understand what is meant by some of the terms that will be used in this document Most Genevac systems feature swung rotors Some however feature fixed rotors with many angled holes for individual tubes But this document however is primarily concerned with swung rotors A swung rotor includes a swing or bucket Below are drawings of typical swings for HT systems Open or standard Side Bridge Fast Stack for microtitre plates Each of these swing types lifts straight out of the rotor On large Mega systems however not shown here the swings are generally fixed in place and cannot be lifted out Which swing is ideal depends on which sample holder is required There is a large range of sample holders which sit in the swings into which tubes vials beakers or flasks are loaded Use of Correct Accessories Genevac supply a wide range of sample holders to cover a variety of plate tu
58. w option to Auto Program the remaining run parameters If OTHER is selected the name should be no more than 31 characters long press ENTER to return to Solvent drop down menu Page 38 of 47 Genevac HT 24 Series II Workstation IR Sensor Control Temperature NOT AVAILABLE WITH SAMPLEGUARD SampleGuard Control Temperature NOT AVAILABLE WITH IR SENSOR NOT AVAILABLE FOR LYOPHILISATION Sample Guard Control Channel NOT AVAILABLE WITH IR SENSOR NOT AVAILABLE FOR LYOPHILISATION Coolheat Enable Pressure NOT AVAILABLE FOR LYOPHILISATION Chamber Temperature Control 10 1562 Issue 1 Revision 10 September 2005 Select Done and press ENTER Press ENTER and input the temperature you wish to limit the sample to during evaporation This can be in the range of 20 to 70 C Note that if not specified the default setting is 40 C Press ENTER and input the temperature you wish to limit the sample to during evaporation This can be in the range of 20 to 70 C Note that if not specified the default setting is 30 C Note this is not available for Lyophilisation Press ENTER and input the channel on which you want to control temperature Channel 1 will normally be assigned to the probe in the sample holder and Channel 2 to the probe in the sample Note that when powered down this setting defaults to Channel 1 as the control channel Note this is not available for Lyophilisation Press ENTER an
59. y pressed ensure EMERGENCY STOP button has been reset THE EMERGENCY STOP BUTTON IS NOT TO BE USED TO SHUT DOWN THE SYSTEMS ON A ROUTINE BASIS 5 2 How to switch on the evaporator s Press the Green power ON button the POWER ON LED will illuminate Both systems will power up The screen on both systems will display the Software Control screen Select the system that you want to use Press the appropriate OPEN CHAMBER button or use the keypad on the evaporator Load your samples following the Safe Loading guide Section 4 of this manual Close and hold the door firmly against the door seal and press and hold the Door Close switch Press the START key on the keyboard to access the Select Run screen The Select Run screen will load up at the last run that was used A series of runs have been preloaded from RUN 51 to RUN 100 inclusive Runs 51 to 98 provide a range of Standard Configurations details on Page 20 Runs 99 and 100 are only for use by engineers for Maintenance Diagnostics Page 18 of 47 Genevac HT 24 Series II Workstation START f Be STOP a J oe a MENU m z 2 B 6 2 D N lt 10 1562 Issue 1 Revision 10 September 2005 5 3 Using the keypad The Series Il keyboard controls and displays have been designed for ease and simplicity in use The keyboard has the most used function keys on the left hand side The right side illuminates when the RUN DATA s
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