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1. Positive Clip ees NOTE The NL530 conditioner will automatically receive input from the module placed directly to the left of it through the rear connectors There are no jumpers present on the NL530 to prevent this ISOLATOR FILTER CONDITIONER NL820 NL135 NL530 Low Pass Hz GAIN OFF 300 500 ine aa 1 50 a 2 o Signal Input From Remote Amplifier To Recording Device N A System Drawing Complete 4 channel system for isolating filtering and conditioning amplified input signals No other leads are necessary as connections are made by the rear connectors Last Revision March 4 1998 File Reference NADOCS COMPANY MANUALS NEUROLOG NL530 SAM Digitimer Ltd Page 2 of 2 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Digitimer NL540 Alternative Gain Module Neurolog SYSTEM Introduction The NL540 ALTERNATIVE GAIN is a four channel NeuroLog System module that can be used with our NL820A ISOLATION AMPLIFIER to attenuate and or invert up to four input signals Inversion or attenuation can be i Activated when the Manual External Gain Control switch is moved from the NORM to the ALT position
2. Digitimer Ltd Page 1 of 2 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL905 Mains Connection The power lead should be connected to a suitable plug The power lead is colour coded in line with international standards and must be connected as follows Insulation Colour Function MAINS VOLTAGE Green Yellow Earth Brown Live Line Hot Blue Neutral The Earth connection MUST be made Before the power unit is plugged into the mains check that the voltage selector on the back of the case is set for the correct mains voltage The appropriate voltage should be opposite the arrow If incorrectly set use a coin of appropriate size to rotate the centre of the voltage selector to align the arrow head with the correct voltage setting Supply range Fuse Value and speed 100 120 V ac TIAL 200 240 V ac T 500mA L Changing the mains voltage will also require you to change the two fuses in the mains inlet They must be 5 x 20 mm in size and the value and speed shown here Grounding The Earth or Ground connection in the mains lead is continuous with the ground points on all module connectors and with the case No provision is made for opening the connection between the case ground system and the mains earth lead Power Unit Protection SECONDARY FUSES l F3 T2AL F4 T2AL The power unit supplies three stabilised voltages 5V 15V an
3. L wal d s 104 ere Ope f 0 greats a a AMPLITUDE se anO To 10 oe MLILT UF w 5 1 a as fe B 12 My d CONTINOUS vat DH z ee SINGLE D 1048 DT i DFF Ea IBOLATOR PS OE e n amp tO sets Repeat Sets Number Sets Pulse Sets Pulse Sets Pulse Cycle C of Pulses N Frequency R Duration W Amplitude A Neu ro Log POWER SYSTEM OFF S On Linear Constant Ourrent Stimulus lealator INPUT _ OUTPUT E Y 1 Oi p 1 Op e e Lr im i0 Input Wax Digimer Lod Number of Pulses N m Pulse Duration W l Pulse rt TI n A Ls Pulse Repetition Frequency R Is Repeat Cycle C Fig NL800A 1 A Typical Stimulus Channel Arrangement Providing Comprehensive Pulse train Facilities connections shown thus are made by rear motherboard links Copyright 2007 Page 2 of 8 Website www digitimer com Digitimer Ltd Tel 44 0 1707 328347 Fax 373153 E mail sales digitimer com Users Manual NeuroLog System NL800A Output Characteristics Load Restrictions The maximum voltage which can appear across the output terminals is limited by the internal battery supply to about 44V This voltage determines the maximum output current for a given load resistance according to Ohm s Law V IR For example if the load resistance across the output terminals is 10 000 ohms the maximum current which can be delivered by the NL800A is approximately 44 10 000 4
4. Constant Red Autozero has failed Excitation Voltage 1V to 15V 10 position control mounted on the PCB Output Voltage lt IIV CMRR gt 90dB 50Hz Onboard Jumper Half Bridge PCB jumper placed over left and centre pins Full Bridge PCB jumper placed over right and centre pins or missing Rear Connections Output signal is routed via internal edge connector to the module on the immediate right of the NL109 We reserve the right to alter specifications and price without prior notification First Issued April 22 2010 Last Revision November 30 2010 Printed November 30 2010 File Reference N Docs Company Manuals NeuroLog NL109 iss00 odt Digitimer Ltd Page 2 of 2 Copyright 2010 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL118 NL118 Octal Band Pass Filter Amplifier u Introduction The NL118 FILTER is an 8 channel first order one pole band pass filter with three low pass and three high pass Time constant filter settings with gain Gain and filter settings can be specially factory set to meet specific user requirements The unit has been designed to meet the specialist requirements of dedicated 8 and 16 channel clinical recording systems using the NL820 Isolated Amplifier with the NL822 2 channel or NL824 4 channel AC Pre Amplifiers and the NL530 Conditioner module The module has a Deblo
5. VOLUME OUT The two middle traces in Fig NL120S 1 show the outputs for the other two positions of the mode toggle switch With the switch in the up position only positive input peaks greater than the adjustable threshold are amplified negative peaks and baseline noise are suppressed With the switch in the down position only negative peaks whose absolute values are greater than the threshold are amplified The threshold increases positively with clockwise rotation of the THRESHOLD control with the toggle switch in the up position and negatively with the toggle switch in the down position This threshold configuration allows separation of spikes which are predominantly positive from those which are predominately negative in addition to the usual selection by amplitude The output signal is in fact inverted which is not shown in Fig NL120S 1 Note that the input to the NL120S need not be analogue waveforms such as spikes at the AC Amp output for example It is sometimes useful to listen to the temporal patterns in the TTL outputs of the NL201 Spike Discriminator Specification Input impedance 10Kohms Bandwidth 10Hz to gt 15kHz Output voltage range 1 5V Minimum resistance across output 3ohms Digitimer Ltd Page 1 of 2 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL120S Power Limit Threshold for L
6. The NL820A ISOLATOR is the module at the heart of the NeuroLog System Isolated Amplifier range of components that meet or exceed the BS5724 and IEC601 1 patient leakage specifications The NL822 and NL824 miniature low noise pre amplifiers and NL134 135 136 144 FILTERS and NL530 CONDITIONER complete the system see system drawing on page 5 General Description The NL820A is a four channel analogue signal isolation module designed to plug into the NeuroLog rack system Opto isolator and transformer techniques are employed to provide signal and power supply isolation from the power supply ground The leakage current between amplifier inputs and ground is less than the limit specified in IEC 601 1 for class CF equipment Refer to Fig NL820A 2 for a module overview Four single ended inputs with a common isolated terminal are provided together with positive and negative isolated supplies for powering external pre amplifiers or control devices Each channel has adjustment of sensitivity by a three step switch to provide x1 x2 and x5 amplification Input signals in the range DC to higher than 10kHz and amplitudes up to 1 volt can be handled by the module Multiple NL820A isolators can be operated in the same NL900 rack to provide higher numbers of channels The NL820A is fitted with an insulated multi way input socket providing connections to the four signal channels and the isolated power source The optional NL822 and NL824 Pre amp
7. 1 0 Attenuation beyond cut off 40dB decade Notch attenuation gt gt 90dB Notch width at 3dB points 20Hz Output voltage range 10V Output impedance 6000hms Rear connections to the motherboard allow Input and Output interconnections between this and adjacent modules without the need of front panel cables Digitimer Ltd Page 1 of 2 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL125 NL126 Le ANH aNARr bb E T ia a gt i l rig g t 4 a ee r ae jpam SAILI r m nA TATI Tea Hip E a e ANDA t 9 lias ae p gt ae gt oe LLL a SH iii v A Rear Connections and jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of external front panel leads INPUT the jumper upper circle allows the Output signal from the module to the immediate left to be connected to the input socket IN or it may be parked for no connection N C as shown OUTPUT the Output signal is always passed to the Input of the module to the immediate right The unit can be set with to have either a 50Hz as shown or 60Hz Notch filter The jumper lower circle is pulled away from the board aligned with the centre pin and the upper for 50Hz or lower for 60Hz pin and pushed back onto the two selected pi
8. 373153 Copyright 2011 Website www digitimer com Users Manual NeuroLog System NL104A NL104A AC Pre Amplifier A C PREAMP sa ase Introduction The NL104A AC Preamplifier is a low noise AC coupled differential amplifier It can be used alone for making recordings from low resistance electrodes see below or with the NL100AK headstage for microelectrode recordings It can be operated in single ended inverting or non inverting or differential modes It has a wide dynamic balance adjustment for asymmetrical inputs useful for balancing out interference and short artefacts a choice of two input time constants and a choice of eight gains The NL104A has provision for limiting the high frequency response a jumper on the printed circuit LF Hz board with 3dB limits indicated eliminating the need for subsequent filtering in some applications NON INVERT Q NYERT Balancing the NL104A An internal 50Hz oscillator is provided for precisely balancing the input Set the input switch to the CM position the rotary gain switch to x1000 and adjust the BALANCE potentiometer using a small screwdriver until the 50Hz signal at the output is minimal A 3 5mV signal will be present when the common mode rejection is 80dB or 10 000 to 1 Better rejection ratios are possible with careful adjustment of the BALANCE control but assessment is difficult without filtering the output signal since the typical output noi
9. Control battery is determined solely by the amplitude and duration of the input pulses and not the output amplitude continuous operation with high duty cycles at the maximum input amplitude i e with the NL510A amplitude dial at 10 00 produces greater battery drain than low duty cycles at low input amplitudes The drain on this battery is the same for each output range The table below Table NL800A 1 is an approximate guide to the life of the Control battery NL510A Dial Duty Cycle Life hours 10 0 50 25 10 0 10 125 10 0 1 1 250 5 0 50 50 5 0 10 250 5 0 1 2 500 1 0 50 250 1 0 10 1 250 1 0 1 12 500 Table NL800A 1 Expected Control battery life The four Stimulus batteries are simultaneously discharge at a rate that depends only on the magnitudes of the output pulses The table below gives a rough guide to the service life for these batteries Pulse Amplitude Duty Cycle E a t E 10mA 50 8 hours 16 hours 10mA 10 40 hours 80 hours 10mA 1 400 hours 800 hours 1mA 50 80 hours 160 hours 1mA 10 400 hours 800 hours 1mA 1 4000 hours 8000 hours Table NL800A 2 Expected Stimulus battery life As the Stimulus batteries discharge their output voltage decreases The first number in the Life entries above indicate the service at which the battery voltage in each battery has fallen to 80 giving a total output voltage available of about 34 4V the second number indicates the hours of service to
10. Digitimer Ltd Page 2 of 5 Copyright 2003 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL405 Trigger selection and relationship to Outputs TRIGGER in Output OUT Output OUT Output Delayed Width as set on board Fig NL405 3 Outputs relationship to Input ve edge trigger TRIGGER in Output OUT Output OUT Output Delayed Width as set on board Fig NL405 4 Outputs relationship to Input ve edge trigger The above two figures show the effect of selecting ve edge or ve edge triggering POSITIVE EDGE ve edge triggering means that the unit will be internally triggered when a rising edge is seen on the input IN socket NEGATIVE EDGE ve edge triggering means that the unit will be internally triggered when a falling edge is seen on the input IN socket This can often be used with an external switch closure such as a foot switch as long as the DELAYED OUT is used the unit is set to RE TRIGGER and the WIDTH is set longer than the contact bounce time which will normally be under 10 ms The unit may also be triggered when the switch is released because of poor contacts and in this instance an external capacitor across the contacts is called for This may need to be found from trial and error but a value of 1uF would be a good starting point Digitimer Ltd Page 3 of 5 Copyright 2003 E mail sales digiti
11. L _ Power Limit 7 B owani Aiae A C Output For f p D Output For Fig NL120S 1 A Input to the NL120S Audio Amplifier B C and D are the three selectable outputs First Issued October 30 2007 Last Revision January 12 2011 Printed January 12 2011 File Reference N Docs Company Manuals NeuroLog NL120S oat Digitimer Ltd Page 2 of 2 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL125 NL126 NL125 NL126 Filters FILTERS NL125 gt 50 NL126 Example Introduction The NL125 NL126 Filter module employs two active sections to control the variable high and low pass characteristics along with a mains frequency Notch filter It is a combination replacement for both the NL125 and NL126 The low frequency cut off point can be set continuously from 0 5Hz to 5kHz with a single turn potentiometer in four switched ranges Similarly the high frequency cut off can be set continuously from 5Hz to 50kKHz in four switched ranges DC and WB wide band switch positions by pass the lower and upper filter sections respectively The unit has two active notch filters which provided for the rejection of line frequency interference this is selectable on the board by the user as either 50Hz as the original NL125 or 60Hz as the original NL126 with a 20Hz notch width 3dB points The
12. OUT OFF ISOLATOR DRIVE OUT Introduction The NL510A PULSEBUFFER converts TTL logic pulses into either pulses whose amplitude can be set to between 0 and 10V pulses or input drive pulses for the NL800 or NL800A Stimulus Isolator The output amplitude is adjusted with a precision ten turn potentiometer and a turns counting dial The mode switch has three positions 0 10V This position allows the 10 turn dial to precisely set the output pulse level to between 0 to 10V and can be used in many applications such as a voltage stimulator relay driver solenoid driver oscilloscope beam brightener etc OFF This position is a useful feature when more than one stimulator is being used ISOLATOR In this position the output pulses are offset to match the input characteristics of the NL800 or NL800A Stimulus Isolator See NL800 NL800A section for further details and system set up etc Specifications Output voltage range O to 10V Output resistance lt 10 ohms Output current 50mA Output rise and fall times lt 1 microsecond First Issued before July 1984 Last Revision January 12 2011 Printed January 12 2011 File Reference N Docs Company Manuals NeuroLog NL510A odt Digitimer Ltd Page 1 of 1 Copyright 2010 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL512 NL512 Biphasic Pulse Buffer BIPHASIC BUF NL512 O
13. if required via the Motherboard in the NL900 Rack and Power Supply Specification Summary IN Input voltage range 15 V max for Full Scale Output 10 V 5 V 2 5 V or 1 V by on board jumper selection Input impedance 1 MQ Frequency response GATE Logic levels Function gt 1 MHz This will usually be limited to less than this by the NL800 TTL compatible ON unit working TTL high gt 2 8 V or no connection OFF unit disabled TTL low lt 0 8 V Input voltage range 15 V max Input impedance 85 KQ Response time lt 5 us ON OFF Switch This overrides the GATE input to disable the module when set to OFF OUT Output DC offset for NL800 lt 0 7 to gt 2 3 V Separately set for each phase Output voltage range Oto 10 V Output current for NL800 up to 20 mA Output impedance lt 10 Q Rear connections to the NL900 motherboard allow an input interconnection for IN or GATE and the module to the immediate left without the need of a front panel cable Digitimer Ltd Page 1 of 4 Copyright 1999 2002 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL512 Connection of NL512 to 2 x NL800 s Bipolar Bipolar Voltage BIPHASIC BUF Current Input NLS12 NeuroLog Output SYSTEM pu OUT STIMULUS ISOLATOR NL800 vf Digitimer Ltd NeuroLog SYSTEM STIMULUS ISOLATOR NL800 Digitimer Ltd With this connection a bipolar vol
14. then rotating them 90 180 or 270 before replacing them in two of the small gold board sockets INPUT the upper jumper allows the Output signal from the module to the immediate left to be connected to either of the three Input sockets or it may be parked for no connection OUTPUT the lower jumper selects which of the two Output signals is passed to the Input of the module to the immediate right or it may be parked for no connection First Issued July 1984 Last Revision July 24 2000 Printed July 24 2000 File Reference NADOCS COMPANY MANUALS NEUROLOG NL505 SAM Digitimer Ltd Page 2 of 2 Copyright 1996 9 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL506 NL506 Analogue Switch AN SWITCH NL506 Introduction The NL506 contains a single pole change over analogue switch The state of which is controlled by a logic signal This signal can be generated externally or by the internal Flip Flop that can be toggled by the negative going edge of a logic input A front panel switch allows direct selection of the switch state which is indicated by an LED The switch is bi directional allowing it to be used as a 1 input 2 output or a 2 input 1 output device Also as the switch is analogue it can handle signals up to 15V as well as being of low enough impedance to handle TTL signals Applications include selection of o
15. 110dB at 50kHz This is achieved with two eight pole Butterworth analogue filters not the lower cost noisier switched capacitor circuitry This module is NOT compatible with the older NL104 Note that the serial number label indicates the model Specification Summary Input voltage range 500mV at NL104A input Filter settings 3dB 18 5kHz Filter type dual 8 pole Butterworth Attn after cut off 320dB decade 96dB octave Noise none added to NL104A Digitimer Ltd Page 1 of 5 Copyright 2000 2006 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL104F 1ST FILTER 2ND FILTER OUT IN OUT IN Jumpers are shown with both filters IN NL104F Component View of PCB NL104F BOARD NL104A BOARD GAIN OFFSET GAIN OFFSET OUT OUT FILTER 1 FILTER 2 On board Jumpers The two sections of the filter may be separately disabled if ever necessary by removing one of the jumpers on the upper edge of the PCB and refitted in the other position The need is NOT expected Digitimer Ltd Page 2 of 5 Copyright 2000 2006 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL104F Fitting the NL104F to an earlier NL104A note the small pcb screen over the Gain control The NL104F is held to the NL104A with two brackets These have a metric thread at each end and the screws ar
16. Manual NL515 NL520 NL530 NL601 NL603 NL606 NL700 NL701 NL702 NL703 NL705 NL730 NL741 NL750 NL751 NL752 NL753 NL755 NL820 NL820 822 NL820 824 NL820 832 NL820 834 NL850A Last Revision File Reference Digitimer Ltd 8 5mA 330mMA 380mMA 40mA 40mA 190mA 420mA 1060mA 75mA 300mA 16mA 260mA May 20 1996 POWER SAM 52mA 8 5mA 16mA 160mA 16mA 8 5mA 13mA 10mA 18mA 30mA 45mA 100mA 140mA 120mA 160mA 39mMA Tel 44 0 1707 328347 Fax 373153 NeuroLog System Power 11mA 6 5mA 6mA 8 5mA 13mA 31mA 6 5mA 21mA 20mA 20mA 9mA 9mA 9mA 9mA 9mA 38mA Page 2 of 2 88 displayed 88 displayed To be added to NL750 LED off To be added to NL750 No Pre amplifier To be added to NL104A Copyright 1996 Email sales digitimer com Users Manual NeuroLog System NL61 NL61 Isometric Force Transducer Introduction The NL61 series force sensors have been widely used in many applications for more than 40 years The NL61 has proved the first choice for applications such as muscular and membrane movement monitoring fluid viscosity measurement and even the force induced by butterfly wings during flight It is most suitable for applications where customers need to measure small forces with a good level of accuracy minimal deflection and a flexible mounting arrangement The NL61 can b
17. Manual NeuroLog System NL62 NL62 Stainless Steel Low Range Dual Cantilever Beam Load Cell Introduction The NL62 is constructed from stainless steel and is available in ranges between 2kg and 50kg The NL62 offers an excellent size performance ratio at a competitive price The stainless steel dual cantilever design enables the rejection of off centre forces making the first choice in a number of material testing and weighing applications We can supply the NL62 on its own or along with our NL109 Bridge Amplifier When ordering please use part code NL62 xx replacing xx with the required range from those given below Features 1 Ranges 2kgf to 50kgf 2 Small Physical Size 3 10000hm bridge resistance 4 Stainless Steel Construction 2 5 10 30 50kg 200 with lt 4 1 calibration shift 2mV V nominall Output Sensitrvity Zero Offset lt t2 FSO Accura lt 0 1 FSO Repeatabilr lt 0 1 FSO Excitation Voltage 10vde recommended 15vdc maximum Bridge Resistance 10000 standard Insulation Resistance gt 1000M0O at 250vdc Operating Temperature Range 20 C to 70 C Compensated Temperature Range 10 C to 60 C Zero Temperature Coefficient lt 0 053 FSO PC lt 40 01 FSOPC opt span Temperature Coefficient lt 4 0 03 FSO C lt 0 01 FSO C optional Environmental Protection Level Connection Type 2 metres 4 core screened PVC cable Wiring Connections ve supply R
18. NL951 cable in most cases IN can be coupled to the COM socket useful when a logic input signal is alternatively sent to one of two destinations Digitimer Ltd Page 1 of 2 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL506 Applications The figure below shows the generation of a logic signal and distribution of an analogue signal to two NL800 Stimulators for bipolar stimulation using common parameters for pulse width and amplitude For a detailed explanation of this application please refer to Application Note 14 available on our website and at the back of the NeuroLog System Users Manual PULSE BUFFER WIDTH DELAY WIDTH DELAY PULSE GEN AN SWITCH Powe NL3O4 wat NL405 NL510 uw Sey es f AT lz i TU ibs Vins SUM UTR 0 MH hte sh i x1 x12 134 3 Come nipt AMPLITUDE jo r 1 e oe CoN TINUICHS CHH Neurology SINS u HD kS D fs a PR ce Y OFF a aa a x OR fe e 30 i DRIVE a Dighimer Ltd f3 oT a ort Mel S First Issued 1992 Last Revision January 12 2011 Printed January 12 2011 File Reference N Docs Company Manuals NeuroLog NL506 odt Digitimer Ltd Page 2 of 2 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL510A NL510A Pulse Buffer AMPLITUDE 0 10V
19. NeuroLog System that allows adjacent modules in most cases to pass signals between each other without the need for external cables For anti theft security the rear panel of the NL905 includes a Micro Slot compatible opening below the CE logo which allows you to attach a security device of the type used to protect notebook computers In addition the module retention bar can be fixed in place by inserting a screw M3 x 10mm not supplied in a hole at the top of the left hand front panel above the NeuroLog System logo When in place this screw locks the bar and prevents removal of modules from the rack ul Vern f oer Br i a hy Tat o p sE Ye oe lt a tg 1 ite ut _ ikay Mo E ei wl a are a Baye oT r pi mm ie Digitimer Unpacking Your NL905 Your NeuroLog System was delivered in a carton which was carefully designed to protect the NL905 case against damage in shipment It would be advisable to keep your carton in case you need to relocate or return your NeuroLog System some time in the future Before You Start Before starting to use your NeuroLog System we would urge you to thoroughly read the sections of the users manual which are relevant to your particular modules as well as the general section entitled NeuroLog System Basics This will introduce you to the operation of the module retention system internal communication methods and other important aspects of the equipment
20. Notch filter provides rejection of line frequency 50Hz NL135 or 60Hz NL136 interference when switched in No switch is fitted on the NL134 Specification Summary Input voltage range Input impedance Filter settings 6dB Cut off accuracy Gain before cut off Attn beyond cut off Notch Attenuation Notch Width 3dB Crosstalk Noise Output DC offset Output voltage range Output impedance 15V max gt 10V operating 1MQ 10 20 30 50 100 200 300 500 1k 2k 3k 5k 10k 20k Hz and WB 2 1 25HZ lt 630Hz 2 62 5HzZ gt 630Hz 1 0 40dB decade 12dB octave gt 50dB 20Hz better than 60dB lt 100uUV rms lt 10mV 10V lt 600Q Rear connections to the motherboard allow Input and Output interconnections of all four channels between this and newer NL820 and NL530 modules without the need of front panel cables NB This module must NOT be placed adjacent to a Counter module in the NeuroLog rack Digitimer Ltd Page 1 of 3 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL134 135 136 Rear Connections and jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of front panel leads This module has the output signals permanently connected to the rear connector for automatic routing to the module on the immediate right The input si
21. Page 1 of 1 Copyright 1995 Users Manual NeuroLog System NL254 NL254 Instantaneous Ratemeter RATEMETER Introduction The NL254 Instantaneous Ratemeter is a replacement for the NL250 255 and NL253 256 Ratemeters It provides two ranges for both pulses per second pps and pulses per minute opm with the rate displayed on a 3 digit display as 000 999 or 00 0 to 99 9 and an analogue voltage output is provided which is proportional to the instantaneous rate A user set trigger threshold controls the voltage at which the NL254 will detect a valid input Each valid trigger is indicated by the green LED illuminating for 10ms Programmable UPPER and LOWER rate limits can be used to monitor when the instantaneous rate is outside a user set frequency window If the upper rate limit is set to 100pps and the measured rate reaches 100pps or higher then the LIMIT output changes from TTL low to TTL high and the red upper limit gt warning LED illuminates for as long as the rate remains beyond or equal to this limit If the lower rate limit is set to 50pps and the measured rate drops to 50pps or lower then the LIMIT output becomes TTL high and the red lower limit lt warning LED illuminates for as long as the rate remains below or equal to this rate As well as the 3 digit display of frequency the NL254 outputs a user selectable analogue voltage of 0 10V or 0 5V at the OUT socket proportional to the instantaneous frequenc
22. a female connector Lemo type RC00250 on the other end NL954 2m 4 way extension cable for NL100A Preamplifier first stage for NL103 Superceded NL103 AC Preamplifier superceded NL107 Recorder Amplifier NL954K 2m 4 way extension cable for NL100AK NL108T1 Pressure Transducer NL850A Isolated Preamplifier single channel NL955 2m 6 way extension cable for NL102 Differential DC Preamplifier superceded with split socket NL955K 2m 6 way extension cable for NL102 Differential DC Preamplifier superceded standard keyway NL956K 2m 6 way extension cable for NL102G DC Preamplifier Longer cables can be supplied for any of the above accessories Plugs cable mounted NL962 Lemo type F00250 s2 7 male connector The standard NeuroLog front panel plug NL963 Lemo type F0304 s3 2 male connector Mates with NL103 AC Preamplifier superceded and NL107 Recorder Amplifier input sockets NL963K Lemo type FGOB304 C035 male connector Mates with NL104A AC Preamplifier and NL108 input sockets NL967K 6 pole plug matches NL102G Digitimer Ltd Page 1 of 3 Copyright 1995 Users Manual NeuroLog System ACCESSORIES NL968K 2 pole plug Mates with NL410 front panel socket NL969P 9 pole insulated plug As used on NL822 824 832 834 Sockets panel mounted NL964 Lemo type RA00250 socket The standard NeuroLog front panel socket NL969S 9 pole insulated socket As used on the NL820 front panel Sockets in line cable mounted N
23. adjusted it will now indicate the resistance of the pipette at the input with a dial reading of 10 0 corresponding to 100Mohms if 100nA is selected for the 50nA range this is 200Mohms or S00Mohms for 20nA or 1000Mohms for 10nA Whenever current is injected through the microelectrode at the In input except for the IMPED CHECK current of course the BRIDGE BAL control may be adjusted to cancel out the resulting voltage across the microelectrode giving the effect that the baseline is stationary during current injection Note that the BRIDGE BAL reading reflects the total ie electrode plus membrane resistance during intracellular recordings Also that the BRIDGE BAL feature operates on the x10 out only the x1 output at all times shows the sum of the electrode potential and the potential developed across the electrode impedance by the injected current Calibrator 100uV or 10mV calibration signals selected by the CALIB toggle switch are available for use with the x10 amplifier section The timing of the calibration signal is the same as that for the IMPED CHECK i e a 150Hz rectangular wave or a pulse determined by the same CALIB TTL GATE IN signal The CALIB signal is however negative rather than positive as for the IMPED CHECK Thus these two cannot be used simultaneously they will add algebraically The TTL gate facility for the calibration signal is especially useful in situations such as averaging synaptic potentials when a calibrat
24. and Clear and two outputs Q and Q all of which drive or are driven from TTL logic i e OV and 5V A LED indicator is illuminated when the Q output is at a high level OUTPUT STATE The table below shows the relationship between inputs and outputs Complement Set Function Static Condition Clear output Set output see below Complement Where is alogic high 5V is a logic low OV or unconnected inputs is irrelevant O is the previous output state is a positive going pulse gt 0QXO0 This is a non stable state it will only remain whilst Set and Clear are both held high N B The Set and Clear inputs override the Complement input that is why the output is only affected by the complement input when both of these are low Digitimer Ltd Page 1 of 2 Copyright 1996 9 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL505 Typical waveforms Q Q TU LAT U i ea EET Q Shows PC regularly reading Q out and then Clearing latch SET and CLEAR are OV or not used This acts a pulse catcher for narrow pulses into a PC On board Jumpers NL505 COMPONENT VIEW O o OO O JMP1 Parked COMPLEMENT CLEAR O O jmP2 Parked The on board jumpers allow a single connections between adjacent modules without the need of external cables The position of these jumpers are changed by gently pulling them away from the PCB
25. and amplitude control fixed OUT PRESET OUT B STOP GATE O 0 FREE RUN PRESET RESET Q 1s pulse interval i e 5Hz set by NL301 B NL603 Output goes TTL low at 10th beat 120ms DELAY to 10th pulse set by NL405 o Here the Neurolog System is producing a continuous series of trigger pulses which can pace a heart at a fixed rate set by the NL301 PULSE GENERATOR The output from the NL301 is used to trigger a DS3 Isolated Stimulator to pace an isolated heart A premature beat can be inserted after a number of regular beats 10 in this example through the use of the NL603 COUNTER and an NL405 WIDTH DELAY The NL603 can be configured to insert this extra stimulus once as shown here or repeatedly after a user specified number of beats After the single extra beat is inserted the user can choose to RESET the NL603 and then switch it back to RUN when another extra beat is required The NL405 allows the user to vary the delay introduced between the last regular beat and the premature beat The NL405 output is passed to another DS3 which provides the stimulus for the extra beat The amplitudes of stimulus for the regular beat and extra beat are independently controlled by the two DS3 Isolated Stimulators Application Note 23
26. battery voltages of about 50 total output voltage available of about 22V Thus with fresh batteries the NL800A will be able to deliver 10mA through any load resistance less than 4 4kohms see Fig NL800A 2 but after 8 hours of continuous service with a 50 duty cycle at the maximum amplitude setting on the 10mA output range only 7 8mA can be delivered through the 4 4kohms load i e 34 4V 4 400 0 0078A In situations where high currents are required and load resistance are near the limits shown in Fig NL800A 2 careful attention must be paid to battery checks and replacement In most applications the entire set has a life of several months perhaps even approaching the battery shelf life As the cost of these batteries is relatively low it is wise to replace all 5 at the same time Digitimer Ltd Page 5 of 8 Copyright 2007 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL800A Battery Fitting The five batteries are accessed via the panel in base of the unit Removal of the two screws will give access It is imperative that the batteries are fitted with the correct polarity orientation This is marked on the batteries and the holders The symbols must match It is recommended that all five batteries are replaced at the same time Battery Checks The battery can be easily checked by putting a voltmeter across the ends of each battery in turn B
27. cost unit and almost continuous representation of the delayed signal However the NL202 due to limitations in bucket brigade delay lines cannot produce delays of more than 50msec nor can it be used for very low frequency DC to 5Hz signals In spite of its apparently continuous output the signal delay in the NL202 is achieved by sampling the input signal at regular intervals and shifting those samples through an analogue memory element with a finite number of locations 512 stages This results in a fixed relation between output bandwidth and the delay 15kHz for 0 5msec delay 1 5kHz for 5msec delays and 150Hz for 50msec delays with a good sine wave output Thus the NL202 is ideal for use with the NL201 Spike Trigger for visualizing the entire waveforms of amplitude discriminated spikes or for producing pre triggered averages of AC signals consistent with its limited delay range The NL202 provides two easily adjustable delay ranges from 0 5 to 5msec and 5 to ba ia 50msec controlled by a front panel toggle switch and a potentiometer Specifications Input Voltage range to saturation 2V Input dynamic range 60dB Input Impedance 100kohms Delay range 0 5 to 50msec in two switched ranges Output gain 1 0 5 Output frequency response 5Hz to 1 5kKHz max delay 5Hz to 15kHz min delay First Issued before July 1984 Last Revision October 30 1995 RIAPNA AAND A 2 2 NAR AAA RTP ANART A oe Digitimer Ltd
28. current is injected through the In input Without a TTL input at the TTL GATE IN input the impedance check waveform is an asymmetric positive rectangular wave approximately 150Hz with an amplitude of 1mV per Mohm at the x1OUT socket Note that the MONITOR OUT signal does not reflect the electrode resistance A TTL pulse eg from an NL403 DELAY WIDTH module applied to the CALIB TTL GATE IN socket located immediately beneath the CALIB switch results in a 1nA impedance check current with the TTL pulse timing injected when the IMPEDCHECK switch is in the ON position The TTL pulse signal can be adjusted so that it occurs at the end of each oscilloscope sweep during penetration for example TTL pulses longer than the 150Hz period will merely gate the 150Hz waveform on The waveform recorded during the injection of the IMPED CHECK current depends on the nature of the recording electrode and on the setting of the NEUTRALIZATION control Pipettes have a flat topped waveform but metal electrodes have a complicated waveform reflecting a small series resistance and a parallel resistance and capacitance Bridge Balance Electrode impedance for pipettes can be determined by another method in addition to the IMPED CHECK When the CURRENT INJECTION switch is put in either the DEP or HYPER position the AMPLITUDE dial is adjusted to give a few nA and the BRIDGE BAL dial is adjusted to restore the baseline to where the BRIDGE BAL control is correctly
29. during count PRESET STOP mode Maximum counting rate SMHz Max number of counters 3 counters for 6 digit resolution Digitimer Ltd Page 1 of 2 Copyright 1995 9 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL603 NOT COUNTED AS RESET HIGH RESET NOT COUNTED AS GATE LOW GATE OUT FREE RUN OUT PRESET RESET OUT PRESET STOP Fig NL603 1 shows waveforms for a single NL603 set to 05 In FREE RUN the counter generates a 0 5 microsecond pulse every time the display corresponds to the thumbwheel switches In PRESET RESET the counter generates a 0 5 microsecond at the frequency of the input divided by n or for random signals every n input pulses where n is the number set on the thumbwheel switches In PRESET STOP the counter output is at a logic high from the start of RESET until the n th pulse at the input after the end of the RESET The counter will remain in the stop position until another RESET If two NL603 s are placed adjacent to each other the number n is the 4 digit number as displayed on the thumbwheel switches When using more then one NL603 all connections should be made to the right hand module and the RESET RUN STOP switch on the right hand module should be used for control switches The other counters should be set for RUN The FREE RUN PRESET STOP switches on all the counters should be set to the
30. either of these positions When the signal is altered this is indicated by illumination of the front panel LED ALT GAIN If the upper toggle switch is placed into the central position the external control options are enabled see overleaf with the four outputs remaining in the state they were immediately prior to this change ALT NORM OS o External Control of Inversion Attenuation with External TTL Pulse Control When the Manual External Gain Control switch upper toggle switch is moved from the NORM position to the centre positon the External Source Selector lower toggle switch and the External Trigger Input Socket become active ALT GAIN With the External Source Selector switch placed to the A right signals will be inverted attenuated in response to TTL pulses at the trigger input Inversion attenuation is triggered by the falling negative edge of an incoming TTL pulse with normal polarity gain returning C D aana cas ie following a second TTL pulse As with manual control the LED will illuminate when the output signals are inverted attenuated IN OFF External Control of Inversion Attenuation with External TTL Gate Control When the Manual External Gain Control switch upper toggle switch is moved from either the ALT or NORM positions to the centre the lower toggle switch and the External Trigger Input Socket become active When the External Source Selector lower toggl
31. externally amplified so that the required Lower threshold is in the range 1 to 5 Volts with the window 200mV to 5V wide If this can not be accomplished the internal gain of x10 may be selected so that signals requiring a Lower threshold of 0 to t500mV and a window of 20 to 5 00mV can be accommodated Although the NL201 SPIKE TRIGGER is specifically designed for spike amplitude discrimination it can be used for events with much longer rise times if amplitude gating is not essential For example pulses can be triggered by QRS complexes in electrocardiograms either at the upper or lower thresholds It is anticipated that the NL201 would be used with an standard low specification Analogue oscilloscope not a Digital Storage Oscilloscope DSO Should a DSO be used the user may wish to modify the speed of the multiplexer see page 4 so that the discrimination levels are displayed more distinctly to the detriment of the display of the signal Alternatively the discrimination levels could be disabled completely see page 6 Digitimer Ltd Page 1 of 6 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL201 Level detection Fig NL201 1 ene area LOWER UPPER GATE Timed GATE No Upper Fig NL201 1 Level detection The thresholds are adjusted with the two potentiometers mounted on the front panel The dial markings for the WINDO
32. from 1 0V output for the 1 36m pressure can be adjusted with the trimmer on the NL108A printed circuit board labelled GAIN Small adjustments can also be made with the BRIDGE VOLTAGE setting but be careful not to exceed the limits for your particular transducer 9 When correctly set up pushing the OUT GND push button should produce the same effect on the output as opening port B to the atmosphere Switching the CALIB toggle switch to its 1 0V position should also produce the same output deflection as opening port B to the 1 36m column of water 10 Steps 6 and 9 can be repeated for the 100mV 1cmH O switch position In this case however the column of water should be 10cm for 1 0V output deflection USE OF THE OUT GND AND CALIB SWITCHES The OUT GND push button is used to locate the zero pressure dc level on the output recording some chart recorders drift A 0 0V to 1 0V calibration deflection is produced on a recording trace by switching the CALIB switch to 1 0V and pushing the OUT GND push button a couple of times Similarly for the 0 0V to 100mV calibration deflection Specification Input voltage range 15V Gain 1V 100mmHg or 100mV cmH O for a pressure transducer having an output of 50uV mmHg DC offset t60cmH O or 40mmHg when switched to the appropriate range Bandwidth DC 150Hz O P voltage range 12V O P impedance 600ohms nom except zero out where O P is s c to ground Bridge supply 0 24V dc 25mA F
33. gt 2 1 2mm gt 3 1 5mm gt 4 2 0mm e g NL101B3 will plug into an NL100AK or NL102AG 2mm pin and hold a glass capillary with an outside diameter of 1 5mm First Issued before July 1984 Last Revision March 25 2010 N Docs Company Manuals Ne Digitimer Ltd Page 1 of 1 Copyright 1995 Users Manual NeuroLog System NL102G NL102G DC Pre Amplifier D C PREAMP Neurolag Introduction BRIDGE BALANCE m The NL102G is a direct coupled pre amplifier designed specifically for oF biological recording With features such as capacity neutralization current injection low leakage current and low DC drift it is particularly suitable for intracellular measurements through high resistance fluid filled electrodes The input stage is conveniently located at the end of a 2m cable for direct attachment to a micromanipulator Other features include electrode impedance check calibrator stimulus bridge balance and DC level adjustment The NL102G is supplied with the NL412 Pulse box which acts as a buzz control to facilitate electrode impalement Remote Headstage The first stage of the NL102G is fitted in a metal tube at the end of a 2m cable This unit is calibrated against the module supplied with it it is NOT interchangeable with other NL102G modules without re calibration the serial numbers on both the headstage and module should match The central 2mm input socket In is the capacity compensated signa
34. input or ground coupling and fast pulse risetime The NL800A is a replacement for the NL800 which used different batteries but had the same electronic circuit Please refer to the correct section of this Users Manual for the NL800 details Operation In the normal operating mode an NL510A PULSE BUFFER produces the appropriate input pulses The NL800A Power switch is turned on the output range is selected and the desired output amplitude is produced at the two output terminals by adjusting the amplitude 10 turn dial on the NL510A The output can be checked by measuring the voltage across a 1kohm resistor connected between the output terminals with an oscilloscope or voltmeter 1V 1mA Driving the NL800A with something other than the NL510A The NL800A requires an input that varies between approximately 1 4V and 10V 0 to 30mA corresponding to NL800A outputs of 0 to full scale Bipolar Stimulation The NL512 Biphasic Pulse Buffer has been designed to allow two 2 NL800A s to be used to produce a bipolar stimulation signal Please refer to the NL512 section of the Users Manual for details Digitimer Ltd Page 1 of 8 Copyright 2007 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL800A PULSE BUFFER PERIOD GEN COUNTER PULSE GEN WIDTH DELAY NLaO4 car NLEDS NL301 a NEADS M510 PERIOD Gil KIO HZ rae _ ees ies Is ITOP
35. of modules which would fit into a standard 483mm 19 case and increased the total system cost Digitimer Ltd Page 4 of 6 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NeuroLog System Basics Rear Panel Connections Non counter modules L Channel 1 le or only signal 2 Cyr 3 ONN Channel 2 Eigar Channel 3 SA SLA 6 Channel 4 ma De ere Or Fig NL Basics 3a NeuroLog Module Edge Connector System as used for non counters View from front Digitimer Ltd Page 5 of 6 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NeuroLog System Basics Rear Panel Connections Counter modules a z BUS 6 O 21 7 O QO Osv USED FOR COUNTERS OD Cle O O4 Ow R OUT 11 OF am 12 m S a 18 OO Oha e S ia i BUS Om E Fig NL Basics 3b NeuroLog Module Edge Connector System as used for counters View from front First Issued May 15 2002 Last Revision September 27 2005 Printed October 21 2005 File Reference N Docs Company Manuals NeuroLog NLBasics lwp Digitimer Ltd Page 6 of 6 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NL900D N
36. offset when the NL104A is used For NL100AK use the jumper is pulled away from the board off the two pins and then returned to just one pin for storage For SE recordings made WITHOUT an NL100AK headstage the jumper is pulled away from the board and then returned on to both the two pins as shown Rear Connections and jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of external front panel leads INPUT there is no appropriate signal that can be rear connected to this module OUTPUT the Output signal is always passed to the Input of the module to the immediate right Digitimer Ltd Page 2 of 3 Copyright 2009 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL104A A IN 12V Yellow Red B IN 12V Green Blue Fig NL104A 2 External view of Input socket as well as wire colours used in connecting plugs The colours indicated in Fig NL104A 2 refer to the insulated wires of the assembled cable NL953K The 15V and 15V pins in the input socket supply power to the NL100AK headstage 4mA 15V is available at these pins for input preamplifiers of the user s own design if the NL100AK is unsuitable If the NL104A is connected directly to the biological preparation through a long miniature screened cable it must be borne in mind that the frequency response of the NL104A may be substan
37. one year from date of purchase No other warranty is expressed or implied Digitimer Limited s obligations being limited to repair or replacement of apparatus found to be defective during the warranty period which is returned carriage paid to our works First Issued before July 1984 Last Revision January 11 2011 N A Dacs Camnanw Maniale Netral aa ACCFESSOR SAM Digitimer Ltd Page 3 of 3 Copyright 1995 Users Manual NeuroLog System POWER Current Consumption of NeuroLog Modules Introduction Each NeuroLog module takes power from some or all of the power supply rails in the NL900 In most cases the NL900 will support any mix of modules 5V 15V 15V NLIO2G s MRMA 40mA NL104A 10mA 36mA 35mA NL100 does not increase this NL106 40mA 40mA with no LEDs on 60mA 20mA with Red LEDs on 20mA 60mA with Green LEDs on NL107 28mA 2 mA NL108 25mA 15mA 46mA 36mA With NL108T1 NL120 12mA 12mA 70mA 70mA O P load 8R I Ps overdriven NL125 6 22mA 22mA NL134 35mA 110mA 110mA NL135 6 35mA 120mA 120mA NL201 65mA 28mA 20mA NL202 10mA 32mA Minimum Delay highest current NL253 22mA 30mA NL256 74mA 33mA 40mA Set to CAL NL301 62mA NL304 120mA NL310 38mA 3 5mA 1mA NL401 250mA NL403 65mA NL410 47mA NL501 25mA NL505 28mA NL506 5 5mA NL510 4 5mA 170mA Digitimer Ltd Page 1 of 2 Copyright 1996 Tel 44 0 1707 328347 Fax 873153 Email sales digitimer com Users
38. pins 5 The pressure transducer can now be plugged into the NL108A module and the voltmeter disconnected after ensuring no drop in voltage TRANSDUCER 1 36m TO NL108 B 6 Attach a three way stop cock to each of the two points of the transducer as shown in the diagram One of these stop cocks A is closed The second at port B is set up so that it can either vent the port to the atmosphere i e zero pressure or set to connect the port to a piece of 3 or 4mm inside diameter plastic tubing The tubing is suspended vertically and filled with water to a height of 1 36 meters the pressure exerted by a 1 36m column of water is equal to that for a 100mm column of mercury continued over Digitimer Ltd Page 2 of 3 Copyright 1996 2000 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL108A 7 With the port B stop cock set to atmosphere adjust the NL108A ZERO ADJ front panel potentiometer so the OV is recorded at the OUT sockets CALIB switch in OFF position and the pressure range toggle switch in the 1 0V 100mm position Now switch the port B stop cock so that the column of water is connected to the transducer The output of the NL108A should give an output of 1 0V if the excitation voltage and sensitivity of the transducer are correct If not check the BRIDGE VOLTAGE setting again also double check the transducer data sheet 8 Deviations
39. polarisable electrodes chlorided silver electrodes micropipettes behave more like resistors than ordinary metal microelectrodes do i e their impedance is more constant as a function of frequency Thus a 10Mohms micropipette acts like a 10Mohms resistor for short pulses as well as long ones The risetime may therefore be quite long for these electrodes approximately 40us electrode DC resistance in Meg Ohms Output Characteristics How Constant is the Constant Current Output The NL800A has more than 900Mohms output resistance at its output terminals Thus load resistance variations from a short circuit 0 ohms to 100Mohms will result in only approximately a 10 variation in output current assuming that the voltage drop through the load does not exceed the 44V limit discussed above Obviously few load situations will vary to this extent and for all practical purposes the output is constant Digitimer Ltd Page 4 of 8 Copyright 2007 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL800A Battery Life The five 5 equal batteries in the NL800A discharge only when a pulse is applied at the input battery drain between pulses is restricted to leakage currents of the order of hundredths of a micro ampere and is therefore negligible These five batteries are split into a single 1 Control battery and four 4 Stimulus batteries The life of the
40. provided by a toggle switch adjacent to each input socket A single time constant of 0 1 seconds applies to the AC operation condition and the input impedance is 1Mohms for each input Output limiting will occur with input signal exceeding 2 5V differentially or single ended regardless of gain setting and common mode levels of up to 3V can be handled Within these limitations the NL106 can be used to provide an output proportional to the difference between two DC signal levels Specification Summary Input voltage range 3V working 15V overload Input impedance gt 1Mohm Gain O to x10 or O to x100 continuously variable by ten turn potentiometer Small signal frequency response gt 1V out gt 30kHz Low frequency cut off in AC mode 2Hz Output voltage range gt 12V Output Impedance gt 6000hms DC offset range 2V at either input ten turn potentiometer adjustment CMRR gt 2500 1 at 50Hz Rear connections to the motherboard allow Input and Output interconnections between this module and other analogue modules without the need of front panel cables Digitimer Ltd Page 1 of 2 Copyright 2001 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL106 lt IN Fit jumper to use rear connection for IN input a vo IN Fit jumper to use rear connection for IN input NC Fit jumper between these two sockets t
41. reduces the effective isolation of the NL800A output which is not normally desirable All of the output current must however pass through both the 1kohm resistor and the electrode load resistance giving an accurate measure on the oscilloscope of the actual output current The oscilloscope input cannot be put directly across the isolator output because it would then shunt the electrode The 1kohm series resistor does not contribute appreciably to the total load resistance for high impedance electrodes such as microelectrodes gross electrodes e g EEG electrode silver hooks etc may require a smaller series resistor e g 10 ohms when high output currents are used Digitimer Ltd Page 3 of 8 Copyright 2007 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL800A NL800 OUT NL800 OUT gt microelectrode TO SCOPE VERT IN GND Fig NL800A 3 Method to monitor current actually delivered Output Characteristics Output Capacitance and Risetime The NL800A has a total output capacitance of approximately 40pF Thus a 1Mohm resistor across the output will limit the output risetime to about 40us As discussed above however metal microelectrodes which are nominally characterised as having an impedance of 1Mohm at 1kHz behave more like 100kohms resistors for short pulses and therefore usually produce risetimes of the order of 10 to 15us Non
42. result from the accidental parallel connection of outputs but the system so connected will not operate correctly When assembling a system exercise care that only one output is connected to each input though of course up to ten inputs can be connected to a single output WARNING If some modules in an assembly operate incorrectly check to see that the back connections are the intended ones failure to correctly set back connection jumpers is the most frequent cause of NeuroLog Systems not doing what they are supposed to do When there appears to be a malfunction in the new arrangement of modules check each back jumper Front Panel Connections Connections through the coaxial sockets on module front panels should be made with screened coaxial cables fitted with appropriate mating male plugs These plugs are high quality precision components and are therefore relatively costly The particular connectors chosen for the NeuroLog System are standard in new nuclear instruments the CAMAC module system replacing the BNC connector It is expected that connectors like those used in the NeuroLog System will eventually become standard on other instrument ranges By providing the internal connection system the total number of cables necessary in a typical system arrangement has been reduced to a minimum lt is vital that the cables used to make external connections in the NeuroLog System are made with high quality screened wire This will min
43. same required position Rear Connections and jumpers The rear edge connector in the NL900 rack allows most adjacent modules to connected together without the need of front panel leads NL603 This module may be placed adjacent to another NL603 for automatic use as a 4 digit counter OUT This module has the output signal OUT permanently connected to the rear connector for automatic routing to the module on the immediate right INPUT There is no provision on this module for input signals to be sourced from the outputs of the module on the immediate left We reserve the right to alter specifications and price without prior notification First Issued 1979 Last Revision March 9 1999 Printed May 2 2002 File Reference N Docs Company Manuals NeuroLog NL603 SAM Digitimer Ltd Page 2 of 2 Copyright 1995 9 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeurolLog System NL703 First Issued before July 1984 Last Revision February 13 1990 NL703 EMG INTEGRATOR The NL703 EMG INTEGRATOR module was designed to produce an analogue signal to represent the amount or strength of muscle activity The unit will accept signals up to 1V which are full wave rectified and applied to a leaky integrator The output of the integrator is buffered and the overall gain is set at unity The time constant of the integrator is selected by a 6 position rotary switch A toggle switch i
44. socket on the NL820A generates a pulse of adjustable width which is coupled via an opto isolator and the connection cable to the pre amplifier The mute period may be adjusted via the trimmer control mounted behind the front panel over the range of approximately 1 to 10 milliseconds timed from the positive going edge of the applied trigger signal Longer mute periods can be achieved by using a logic signal of the required period to override the internal pulse width generator 10us lt t lt 1ms 2 lt V lt 15 Input Impedance 10kohms ISOLATED COMMON ISOLATED ISOLATOR OUTPUT COMMON 1 to 10ms TO PRE AMPLIFIER 13V MUTE PERIOD ADJUSTABLE FROM TRIGGER PULSE START gt 10ms ISOLATED COMMON ISOLATOR OUTPUT TO PRE AMPLIFIER MUTE PERIOD SET BY TRIGGER PULSE WIDTH gt 10ms Fig NL820A 3 MUTE CONTROL CONDITIONS Fig NL820A 3 illustrates the mute control requirements Safety It should be self evident that by ensuring that a high impedance path is presented to any earth return current that could be present under fault conditions the NL820A will provide a higher order of electrical safety than conventional amplifier components Care should therefore be taken to preserve the isolation barrier created within the NL820A module by avoiding any unintentional ground connection to the amplifier inputs or isolated power supply At 50 60Hz power line frequency the impedance present between the input circuit common term
45. the insertion and withdrawal of modules difficult Even slight distortion of the case results in impaired operation of the module retention bar Switching the Mains Power On The NL900D or NL905 power switch should be switched on BEFORE connections are made to biological preparations Failure to disconnect the preparation before switch on may result in some ground current flow of the order of a few micro amps through the preparation while the supplies settle Analogue Versus Logic Modules NeuroLog modules can be grouped together according to the kinds of inputs and outputs they require Some require analogue voltages varying from micro volts to volts Others are designed for standard TTL Transistor Transistor Logic signals Examples are Modules Requiring Analogue Voltages Modules Designed for Standard TTL Signals NL102G DC Pre amplifier NL301 Pulse Generator NL104A AC Pre amplifier NL304 Period Generator NL106 AC DC Amplifier NL401 Digital Width NL120S Audio Amplifier NL501 Logic Gate NL125 126 Filters NL603 Counter The NL201 Spike Trigger and the NL515 Interface modules for example provide analogue to logic interfaces converting analogue inputs into TTL pulses which can be utilised by other modules Other modules convert in the opposite direction e g the NL510 Pulse Buffer converts TTL pulses into analogue pulses which can be used to drive relays provide voltage stimulation etc Digitimer Ltd Page 1 of 6 Copyr
46. to display GATE pulses in No Upper mode where there is no doubt about which spikes have peaks in the window This method forces an awareness of each spike waveform and makes it less likely that different spikes with similar peak amplitude will be confused spikes with the same amplitude produced by neighbouring cells are simultaneously recorded more often than one might suppose The second method of setting the NL201 s thresholds is simply to measure spike amplitudes at the NL201 input with a monitoring oscilloscope and to set the thresholds from the dials This may be the only method possible if the spike firing rate is low and somewhat unpredictable The display shown in Fig NL201 2 is useful when the spikes of interest occur more frequently than a few per second The third method is purely displaying the MONITOR signal on an oscilloscope and setting the levels appropriately Perhaps the best method however for visualising the spike discrimination process is to use the NL201 SPIKE TRIGGER with the NL741 ANALOG DELAY or NL202 AC DELAY module By delaying the spike signal and triggering the oscilloscope time base with the GATE pulse only those spikes which initiate GATE pulses will be displayed these will be seen in their entirety including portions of their waveform which precede the trigger thresholds The GATE output can be internally selected to occur under one of two conditions In both cases it would occur after the input signal
47. with a method of removing any DC potential from the internal coupling Capacitors that may occur whilst arranging the electrodes on the patient This function can also be performed remotely via the MUTE socket on the NL820A Digitimer Ltd Page 1 of 5 Copyright 1996 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL844 Front Panel NL844 Pre Amplifier DEBLOCK Digitimer Ltd The Front Panel of the NL844 showing the 4 differential input channels and COM connectors along with the deblock button The only Front Panel control is the Deblock push button Pressing this modifies the internal circuitry so that any blocked AC stages are discharged of their DC offsets Good Recording Practice Some of the secrets of obtaining low interference signals are Equal length and design material electrode leads to a channel Equal routing of electrode cables for a channel Leads should be gently twisted together so as NOT to form gaps between them Low electrode impedance lt 5k ohms Equal electrode impedance on both sides of an amplifier Routing of electrode leads away from any electrical magnetic stimulating source If leads do need to cross ensure that they do so at right angles The two wires of stimulating leads should be gently twisted together so as to NOT form gaps Placement of the COM electrode on the patient between th
48. 00nA current injection at 30Hz 6 1 duty cycle i e 100UV kKQ RTI Referred To Input 3 10 30Hz with control of channels in pairs gt 35kHz on all gains when used with NL820A Manual push button or logic signal via the MUTE socket on the NL820A actually shifts LF cut to gt 220Hz 153 x 51 x 178 mm W x H x D 780g Including cable 2m nom NL844P 10 Bk 10 mating plugs Black NL844P 10 Bu 10 mating plugs Blue NL844P 10 Rd 10 mating plugs Red NL844P 9 mating plugs 1 x Black 4 x Blue amp 4 x Red We reserve the right to alter specifications and price without prior notification First Issued June 7 1995 Last Revision September 7 2005 Printed September 7 2005 File Reference N Docs Company Manuals NeuroLog NL844 iss02 lwp Digitimer Ltd E mail sales digitimer com Page 5 of 5 Copyright 1996 2005 Tel 44 0 1707 328347 Fax 3738153 Website www digitimer com Digitimer NeuroLog System 4 Channel Isolated Amplifier System with Filtering and Signal Conditioning CONDITIONER NL530 GAIN OFF 10 ISOLATOR NL820 Pre Amplifier IN IN DEBLOCK N Digitimer Ltd 2 0000 0000 A 3 4 Overview Using the NL820A ISOLATION AMPLIFIER with an NL844 4 CHANNEL AC PREAMPLIFIER replacing the NL822 4 the NeuroLog System becomes a flexible and upgradeable multi channel isolated amplification system for research app
49. 100AKS headstage amp NL100C module Electrode Chambers DC Pre Amplifier AC Pre Amplifier Steep Filter Addition for NL104A AC DC Amplifier Pressure Amplifier Disposable Pressure Transducer Isolated Pressure Transducer type SP844 Bridge Amplifier Octal Band Pass Filter Amplifier Audio Amplifier Filter Low cut High cut and 50Hz 60Hz Notch 4 Channel Low Pass Filter 4 Channel Low Pass Filter and 50Hz 60Hz Notch 4 Channel High Pass Filter Spike Trigger Instantaneous Ratemeter ppm pps Pulse Generator replaces NL300 XY Ergometer Period Generator replaces NL303 Width Delay inc NL405 Comparison with NL401 and NL403 Calibration Module Pulse AND OR Logic Gates Flip Flop Analogue Switch Pulse Buffer updated version of NL510A Biphasic Pulse Buffer Conditioner 4 channel Alternative Gain Pulse Integrator Page 1 of 2 Tel 44 0 1707 328347 Fax 3738153 Copyright 2013 Website www digitimer com Users Manual NeuroLog System CONTENTS NL603 Counter NL703 EMG Integrator NL730 Pulse Shift NL800A Stimulus Isolator Constant Current NL820A Isolation Amplifier 4 channel NL844 4 Channel Remote Pre Amplifier Applications A collection of Application Notes has been compiled at the back of this manual for your reference These and more recently added applications are downloadable in colour as PDF documents from our website at www digitimer com neurolog Indicates that a users man
50. 30Hz Channels 1 and 2 are set for a LF Cut of 30Hz Centre 10Hz Channels 1 and 2 are set for a LF Cut of 10Hz Up 3Hz Channels 1 and 2 are set for a LF Cut of 3Hz Gain upper switch described lower switch is the same but for Channels 3 amp 4 Up x100 Channels 1 and 2 are set for a gain of 100 Centre x1k Channels 1 and 2 are set for a gain of 1 000 Up x10k Channels 1 and 2 are set for a gain of 10 000 Digitimer Ltd Page 3 of 5 Copyright 1996 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL844 Impedance Checking When the rear panel Impedance checking switch is placed in either the VE or VE positions a 100nA current at 30Hz is injected into the signal source of all channels on either the Red or Blue sockets respectively This current signal generates a voltage across the source impedance preparation patient at the level of 100uV for each 100002 of source impedance This signal will be amplified by the Gain selected on the NL844 and NL820A before it is available for monitoring at the output of the NL820A An indication of the signal seen depending on the Gain setting and the Source Impedance is presented here Source Impedance 1 0000 5 000 10 0000 xi00 10mV pk pk 50mV pk pk 100mV pk pk o xtk 100mV pk pk 500mV pk pk 1V pk pk xk 1V pk pk 5V pk pk 10V pk pk Technically this is 100M ohm Gain controls Signa
51. 4 135 136 and NL530 modules without the need of front panel cables NB This module must NOT be placed adjacent to a Counter module in the NeuroLog rack Digitimer Ltd Page 1 of 2 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL144 Rear Connections and jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of front panel leads This module has the output signals permanently connected to the rear connector for automatic routing to the module on the immediate right The input signals can be disconnected from the outputs of the module on the immediate left if they are inappropriate This is done by removing one of the jumpers in the lower rear corner of the PCB for each channel to be disconnected The jumpers can be parked so that they are not lost by placing them on just one of the pins as shown for channel 1 We reserve the right to alter specifications and price without prior notification Last Revision October 21 1998 File Reference N DOCS COMPANY MANUALS NEUROLOG NL144 SAM Page 2 of 2 Copyright 1996 8 Digitimer Ltd Tel 44 0 1707 328347 Fax 373153 Website www digitimer com E mail sales digitimer com Users Manual NeuroLog System NL201 NL201 Spike Trigger SPIKE TRIG NL201 Introduction The NL201 SPIKE TRIGGER is a gated ampl
52. 4mA in spite of the fact that the Output Range switch may be set for 10mA and the NL510A set for an amplitude of 10 00 The shaded region of Fig NL800A 2 shows realisable output currents for 5 decades of load resistance Bear in mind when considering Fig NL800A 2 that electrodes in tissues do not behave as resistors they may have much lower effective series resistance for narrow pulses than for DC inputs due to polarisation most metal electrodes polarise with DC inputs A typical tungsten microelectrode for example has a DC resistance of about 200Mohms an impedance of 1Mohm for 1kHz sine input and an impedance of perhaps only 100kohm for a 100us pulse a 2000 1 ratio Fig NL8O00A 2 predicts that this electrode will pass about 400UA for short pulses but only about 0 2uA for very long pulses ImA 100pA 10pA GY Y 40 400 OUTPUT CURRENT 0 1pA 1K 10K 100K 1M 10M 100M 1000M LOAD RESISTANCE ohms Fig NL800A 2 Graph showing the Current that can be delivered dependant on the load Resistance Currents can be delivered to loads within the hatched area Output Characteristics Checking Actual Output Current If there is some doubt that the load resistance is low enough to allow operation within the shaded portion of Fig NL800A 2 the actual output current can be monitored with the arrangement shown in Fig NL800A 3 Note that the 1kohm monitoring resistor is connected directly to the preparation ground this obviously
53. An onboard jumper allows the user to DP set the NL109 to a Half Bridge mode for single ended inputs x1 Features Include G HF CUT 10 Oa otk Wide gain range Wide high frequency cut range Integral power supply for bridge excitation Excellent DC stability AC mode with two time constants 0 1s and 10s Autozero button for rapid automated zeroing of DC offset Accepts NL100AK headstage for DC microelectrode recordings Optional Half Bridge Setting allows single ended amplification B P 5 ei 10k 0 3 30k pc LF CUT Hz 0 1 10 OUT Input Socket CONOR WND Bridge INPUT Cy Excitation E Bridge INPUT Excitation The front panel IN socket seen from the front of the NL109 panel If a NeuroLog System transducer is not being used with the NL109 an NL963K Plug or NL953K Open Ended Cable must be correctly wired to the particular transducer being used Bridge Excitation Voltage Sch vonage SM vonage 0 1V 5 8V 1 2V 6 9V 2 4V 7 10V 3 5V 8 12V 4 7V 9 15V PCB mounted Bridge Voltage setting control set to 1V Once the correct voltage has been decided upon the excitation voltage control can be set by inserting a flat bladed screwdriver into the white arrow slot and rotating to the correct number Note that the voltage is generated symmetrically about zero i e Position 3 5V is 2 5V For use with the NL100AK o
54. Because many modules have multiple inputs and outputs internal interconnections must be programmed Inputs which are to be connected through the edge connector are selected or programmed by making electrical connection between pairs of 1mm sockets on module printed circuit boards These sockets are located at the back top corner of the board To effect connection two sockets are bridged by the black jumper plug supplied The pin sockets are labelled in some modules on the conductor side in others on the component side of the PCB to indicate the associated input or output Input sockets and jumper always form the top group when both input and output jumpers are present Each jumper can also be placed in a neutral position with one of its pins in a PCB hole lacking a socket so that no connection is completed through the edge connector Many NeuroLog modules have jumpers for outputs as well as inputs if they have more than one output e g GATE UPPER and LOWER outputs for the NL201 Spike Trigger The jumper is used to select which if any of these outputs are relayed to the neighbouring modules If there is only one output in a particular module available for connection through the edge connector it is usually connected directly to the edge connector Such outputs will automatically be connected to the inputs of the right adjacent modules unless the input jumpers on the right adjacent modules are open circuited by placing them in their neu
55. CB then rotating them 90 180 or 270 before replacing them in two of the small gold board sockets In the Parked or N C position the jumper is placed in only one gold socket and a parking hole INPUT the upper jumper allows the Output signal from the module to the immediate left to be connected to the GATE 1 IN 1 input socket B 1 or it may be parked for no connection N C OUTPUT the lower jumper selects which of the four Output signals is passed to the Input of the module to the immediate right We reserve the right to alter specifications and price without prior notification First Issued before July 1984 Last Revision March 26 2003 Printed April 5 2005 File Reference N Docs Company Manuals NeuroLog NL501 02 lwp Digitimer Ltd Page 3 of 3 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL505 NL505 Flip Flop Introduction FLIP FLOP NL505 The NL505 FLIP FLOP can be operated either as a set reset flip flop or as a toggled complementing flip flop This makes it useful in setting up conditional and single shot stimuli and testing logic outputs for the presence of pulses logic levels etc The NL505 is useful in stretching or latching narrow outputs from units such as the NL201 Spike Trigger so that they can be read by a PC IN The module has three inputs Set Complement
56. H O at the transducer port An internal voltage calibrate provides the appropriate deflection 1 0V or 100mV for these two ranges Other features include excellent DC stability a push button switch for setting the zero pressure baseline on the recording instrument and a sensitive zero offset control Although the NL108A is designed to mate perfectly with our own NeuroLog pressure transducers NL108T1 NL108T2 NL108T3 or NL108T4 due to its internally adjustable gain and bridge excitation voltage it can be used with a variety of other standard pressure transducers NB The NL108A has the same functions and front panel as the earlier NL108 but contains updated circuitry Connections to Transducer If a NeuroLog transducer is not being used an input plug type NL963K must be correctly wired to the particular pressure transducer to be used with the NL108A The front panel socket seen from the front of the NL108A panel has the following connections INPUT BRIDGE EXCITATION INPUT BRIDGE EXCITATION The signals are described in terms of the function of the NL108A These connections are the same from the soldering end of the plug to be fitted to the transducer lead Digitimer Ltd continued over Page 1 of 3 Copyright 1996 2000 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL108A Set Up The NL108A is supplied calibrated for
57. L100AK to a micro manipulator or clamp etc 2 Three input cables are supplied two with a stackable 1mm pin connector each and one with a short U shaped link see below for application 3 A 1mm stacking plug and a 2mm pin These are used to make connections with microelectrodes as described below Electrode Connections Where possible it is recommended that microelectrodes are attached directly to the NL100AK input so that the lead length between the NL100AK input and the electrode is minimised even a few centimetres of lead may result in substantial mains interference pick up Fluid Filled Pipette Electrodes When using fluid filled pipette electrodes it is recommended that an electrode chamber part no NL101 is used Digitimer Ltd Page 1 of 2 Copyright 1995 9 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com2 Users Manual NeuroLog System NL100AK Metal Electrodes Metal microelectrodes may be connected by using an electrode holder part no NLO4 Alternatively the user can adapt the 2mm connector Supplied to suit the particular electrode used A common solution is to use a short length 5 10mm of hypodermic needle tubing soldered to the pin keep this connection as short as possible for low interference When the NL100AK HEADSTAGE is used in conjunction with the NL104A AC PREAMPLIFIER it is important that the A B position is selected on the NL104A input selector switch Thi
58. L965 4 pole in line socket matches NL100A NL965K 4 pole in line socket matches NL100AK NL850 NL966K 6 pole in line socket matches NL102GH Adaptors NL957K 2m 4 way for NL100A to NL104A To connect older NL100 or NL100A to a NL104A NL960 Adaptor with a BNC plug to Lemo socket This adaptor makes cables with BNC plugs at one end unnecessary NL961 T or more aptly Y connector Lemo type FY00250 can be used to make a branched connection at front panel socket NL969T T connector assembly to allow two NL822 832 s to be connected to a single NL820 and used as channels 1 to 4 Accessory kits NL973A NL100AK headstage accessory kit As supplied with each NL100AK NL976 NL102G headstage accessory kit As supplied with each NL102G Other items NL910 Blanking Panel NL970 10 Gold plated 1mm stacking plug with heat shrinkable sleeve Pack of 10 For use with NL100 NL102 and NL800 NL972 10 Gold plated 2mm plugs Pack of 10 For use with NL100A NL100AK and NL102G NL980 Edge connector extender cable Allows access to both sides of a working module for trimmer adjustments calibration and servicing NL985 Loudspeaker for NL120 NL80Obatt Set of 3 batteries for NL800 NLMANNeuroLog System Operators Manual As supplied with each NL900 Digitimer Ltd Page 2 of 3 Copyright 1995 Users Manual NeuroLog System ACCESSORIES GUARANTEE All Digitimer Limited products are guaranteed against defects in materials and workmanship for
59. L9OOD Case and Power Unit The NL900 NeuroLog module frame and power supply are housed in a fully finished enclosed case The case has carrying handles and is supplied with bolt on rack mounting hardware so that it can be located either in the rack or on the bench top The base is fitted with rubberised feet and the front pair may be extended so as to raise the front of the unit These are easily removed if required for rack mounting The NeuroLog case has an integral module retention system consisting of a simple slide action lever on the power supply panel Thus fittings such as retained screws D Locks etc on individual module front panels are unnecessary this simplifies the modules mechanical design reduces their cost and greatly improves the ease with which rapid changes in module arrangements can be made The NeuroLog power supply produces three voltages 15V 5V and 15V stabilised against line and load variations The voltage outputs are rated at 650mA 3 0A and 650mA respectively All three supplies have internal fold over current limiting the 15V supplies and in addition are protected with rear panel fuses Each supply has less than 15mV line ripple at maximum load The power supply transformer employs sectionalised Winding former for additional safety and complies with the safety requirements of BS EN 60601 1 but is NOT listed as a Medical Device The power supply provides sufficient power for any mix of single width NeuroL
60. MANUAL CONTROL ii Initiated and terminated toggled by successive TTL logic pulses at the External Trigger Input Socket TTL PULSE CONTROL iii Activated for the duration of a TTL high input at the External Trigger Input Socket TTL GATE CONTROL Four front panel DC offset controls allow small baseline offsets to be trimmed out at the input stage so they are not attenuated or inverted at the output stage Manual Inversion Attenuation Manual External Gain Control Switch ALT GAIN FR External Source Selector Triggered LED Polarity or Gated Indicator Signal Inputs Signal Outputs External Trigger Input Input DC Offset Controls Moving the Manual External Gain Control switch from NORM through the centre position to ALT results in inversion attenuation of all four signal inputs according to the individual settings on the printed circuit board see Internal Switches and Jumpers If this toggle switch is moved back to the centre the output signals will remain altered and the LED will remain lit until it is returned to the NORM position In this way manual control allows the user to reset preset the status of the outputs so as to determine the effect of an incoming logic pulse in TTL Pulse Control Mode overleaf The size polarity of the four input signals can be manually changed by moving the upper toggle switch from NORM x1 output same as input to ALT altered The lower toggle switch has no effect in
61. N ran gt Pa OFF ait PHASE Introduction The NL512 BIPHASIC PULSE BUFFER is the interface between any bipolar signal and two of the NeuroLog NL800 ISOLATORS so that bipolar isolated constant current signals can be used for stimulation This is current out for voltage in The NL512 can also control two independent NL800 s one with the positive phase and the other with the negative phase of a DAC output The NL512 features a high input impedance and four input ranges to allow a number of different modules or an external signal Such as from the DAC in a PC to be used for the input signal A GATE input allows multiple units to be connected to a single analogue source with each channel being digitally enabled separately The switch in the OFF position disables the module The NL800 ISOLATOR features no battery usage except for when a stimulus is being presented which is achieved by using an input opto coupler This does suffer from having a low impedance and a DC offset which is different for each unit but the NL512 removes these problems The NL512 provides easily adjustable internal finger controls for the DC offset of each of the NL800 s An on board jumper allows the unit to be driven by one of four different ranges for Full Scale current output from the NL800 s These are 10V 5 V 2 5 V and 1 V The 1 mm jumper system on the board allows the unit to be driven from the unit on its immediate left
62. NeuroLog System as it provides the fine grain 1 microsecond increments necessary for digital control of pulse width cycle duration delay etc using the NL603 Counters The pulse repetition rate is controlled by two rotary switches A ten position switch gives 8 decades of control between 1 microsecond and 10 seconds plus 30 and 60 seconds The other switch is a multiplier with settings of x1 x2 x5 x10 The operation of the NL304 is self explanatory except for the GATE IN and RESET inputs No output pulses are produced when the GATE IN input is held at a low logic level when the input goes high the gated output pulses are synchronously generated the GATE IN input is high when no external connection is made to it A brief high logic pulse at the RESET input also synchronises the output pulse train the first pulse generated following the reset pulse is delayed one period from the negative edge of the input pulse A sustained high logic level at the RESET input inhibits output pulse generation TTL pulses 0 01 1 microseconds to 10 minutes 1 10 100 microseconds 1 10 100 milliseconds 1 10 30 60 seconds 1 2 5 10 0 5 microseconds 1st Pulse not produced DA p la Period selected or Switch to RESET First Issued 1996 Last Revision March 15 1999 Printed March 15 1999 File Reference NADOCS COMPANY MANUALS NEUROLOG NL304 SAM Digitimer Ltd Page 1 of 1 Copyright 1996 9 E mail sa
63. OMPANY MANUALS NEUROLOG NL100AK SAM Digitimer Ltd Page 2 of 2 Copyright 1995 9 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com2 Users Manual NeuroLog System NL101 NL101 Electrode Chamber Introduction The NL101 Electrode Chamber is constructed using a sintered silver silver chloride Ag AgCl pellet which provides a drift free stable DC potential unaffected by the passage of small currents during experiments The pellet is bonded to a corrosion resistant metal pin and sealed in a clear perspex chamber The chambers are bored to accept readily available glass tubing see sizes below and colour coded for easy identification The glass electrodes are retained within the chamber by a Neoprene rubber end washer which also prevents evaporation and leakage of the electrolyte solution The NL101 Electrode Chambers are compatible with all NeuroLog System headstages They are available with two different plug sizes NL101A 1mm plug fits older rectangular headstages eg NL100 NL102 NL101B 2mm plug fits the newer round headstages eg NL100AK and NL102AG Both of these are available in four sizes to fit glass capillaries 1 0mm outside diameter Yellow 1 2mm outside diameter Green 1 5mm outside diameter Blue 2 0mm outside diameter Red RWRNDM wa ww S Part Number description NL101xy Pin size glass size A 1mm lt gt 1 1 0mm B 2mm lt
64. R Stimulus amplitude is set by the NL510 PULSE BUFFER and both NL800 units must be set to the same output range Dotted dashed lines between modules indicate signal passage through their rear connections while solid lines indicate where cables are required Jumper positions Required NL405 1 Input set to N C Output set to OUT NL301 Input set to GATE NL405 2 Input set to IN Output set to OUT NL510 Input set to IN NL506 Input set to N C PULSE BUFFER AN SWITCH Digitimer Ltd t Figure 1 Burst Repetition Set by external start pulse Burst Duration Set by first NL405 1s i Stimulus Frequency set by NL301 55Hz gt veiPhase Duration set by NL301 Toggle switch 500ps Total Output Duration set by second NL405 1ms LI i Li Stimulus Amplitude Set by NL510 Application Note 14 Figure 2 Digitimer NeuroLog NeuroLog System SYSTEM Using the NL405 Delay Width Module amp NL501 Logic Gate to produce pairs of pulses with interval control from a single trigger input such as the NL301 Pulse Generator PULSE GEN WIDTH DELAY NL405 or 100us 1MS C O l O E DS2A or DS3 Stimulus Isolator Triggered by ve edge Here the Neurolog System is being used to produce a repetitive single trigger pulse and convert it into a pair of pulses with a user controllable delay between them This pair of pulses can then be passed through an OR Logic Gate wit
65. URRENT INJECTION can be used for this adjustment Optimal adjustment produces the fastest risetimes on these signals without overshoot or ringing Excessive clockwise adjustment of the NEUTRALIZATION control will result in oscillation and current injection Over compensation also increases noise levels so careful adjustment of this control is essential for optimum performance During penetration and until the precise waveforms in recordings are importance it is advisable to use the NL102G in a slightly under compensated state With low impedance electrodes and metal microelectrodes the NEUTRALIZATION control is usually set in the minimum ie fully anti clockwise position NL412 Pulse Box It has been found that electrode penetration of the cell membrane is improved if the headstage amplifier is in an oscillating condition Newer NL102G s are fitted with an input which connects to the NL412 Pulse Box included with new NL102G s The NL412 has a push button which when depressed activates the capacity compensation circuit applying maximum compensation This normally induces oscillation in the current injection system and aid impalement of the cell Note that older NL102G s had a button on the front panel rather than a socket for the NL412 to connect to Clean Dye Control This is a switch which when operated causes high injection currents to be applied to the electrode It can therefore be used to dye stain the preparation at the end of an experime
66. Users Manual NeuroLog System USER MANUAL Neurolog The NeuroLog System USER MANUAL NeuroLog System is a registered trade mark of Digitimer Limited The NeuroLog System is designed and manufactured in the UK by Telephone 01707 328347 Digitimer Limited Welwyn Garden City Fax 01707 373153 Hertfordshire Int 44 1707 373153 AL7 3BE England E mail sales digitimer com Website www digitimer com Digitimer Ltd Page 1 of 1 Copyright 1972 2000 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System CONTENTS Contents Module No NLBASICS NL9OOD NL905 ACCS POWER NL61 NL62 NL63 NL100AK NL100RK NL101 NL102G NL104A NL104F NL106 NL108A NL108T2 NL108T4 NL109 NL118 NL120 NL125 126 NL134 NL135 136 NL144 NL201 NL254 NL301 NL280 NL304 NL405 NL410 NL412 NL501 NL505 NL506 NL510A NL512 NL530 NL540 NL601 Digitimer Ltd E mail sales digitimer com Description NeuroLog System Basics Case System and Power Supply Unit Compact Case System and Power Supply Unit Accessories available for the NeuroLog System Current Consumption of NeuroLog Modules Isometric Force Transducer Stainless Steel Low Range Dual Cantilever Beam Load Cell Aluminium Medium Range Dual Cantilever Beam Load Cell Pre Amplifier First Stage Pre Amplifier First Stage with stimulus relay inc NL
67. W HEIGHT potentiometer show the Lower threshold see Fig NL201 1 in volts the Upper threshold however is equal to the WINDOW HEIGHT APERTURE settings The values of this arrangement are twofold Firstly the separation between the two thresholds i e the APERTURE can be kept constant and the position of this amplitude window can be shifted with respect to the baseline with a single potentiometer WINDOW HEIGHT Secondly it is impossible to incorrectly adjust the two thresholds as would easily be possible if each was adjusted independently e g the Upper threshold cannot be lower than the Lower threshold Input signals used to drive the NL201 may have appreciable DC components e g the vertical output signal of an oscilloscope will have a DC level which depends on the setting of the oscilloscope s vertical position knob but the spike amplitudes are measured with respect to the baseline The input of the NL201 is normally AC coupled for that reason low frequency response approximately 0 8Hz to simplify threshold adjustments An internal jumper allows the coupling capacitor to be shorted if DC discriminations are required The WINDOW HEIGHT APERTURE and INPUT RANGE labelling are therefore AC amplitudes The spike at the left in Fig NL201 1 does not cross either threshold and therefore no output pulses are produced The middle spike crosses only the Lower threshold i e its peak is within the window bounded by the two thresho
68. anual Specification Summary Input Voltage range Impedance Protection Time constant Gain Thresholds Lower range HEIGHT Aperture range WINDOW Triggering and levels Calibration Outputs UPPER LOWER GATE MONITOR Internal Jumpers AC DC Coupling GAIN MONITOR OUT GATE Pulse occurs NeuroLog System NL201 10V 1MQ 100 Volts maximum 0 2 second or DC internal jumper x1 or x10 internal jumper NB after AC coupling 0 to 5 Volts positive or negative 0 2 to 5 Volts positive or negative positive or negative slope 10 TTL 230 micro second 10 pulse TTL 200 micro second 10 pulse TTL 15 micro second 10 pulse Input signal x Gain plus Upper and Lower levels Input is DC coupled or a 0 2 second time constant x1 or x10 on input signal Purely input signal or signal plus levels a LOWER pulse width after signal goes through Lower if it has not crossed the Upper b As signal re passes Lower towards zero without having crossed the Upper We reserve the right to alter specifications and price without prior notification Digitimer Ltd E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Page 5 of 6 Copyright 1996 8 Website www digitimer com Users Manual NeuroLog System NL201 Jumpers NL201 COMPONENT VIEW Fig NL201 3 On board jumpers LK1 Input Coupling Jumper the pins together for DC coupling LK2 Signal Input Gain Jumper the pins toget
69. any of our supplied NeuroLog pressure transducers which have a stated accuracy If a more precise calibration is required or a different transducer is to be used you will need to perform the following procedure 1 Check the data sheet of the particular transducer you wish to use with the NL108A for its EXCITATION VOLTAGE at its rated output in the case of the NeuroLog transducers this is 10 0V The NL108A is designed so that the excitation voltage may be varied between 0 and 11 volts with the preset mounted on the board This is so that damaging voltages cannot be applied to the NeuroLog transducers If voltages up to 24 volts are required a single resistor change is required see circuit diagram and assembly drawings for the NL108A 2 Attach a good isolated voltmeter between the two pins on the NL108A printed circuit board marked BRIDGE VOLTAGE and The voltages at these pins are symmetrical above and below OV i e ground or earth DO NOT GROUND EITHER OF THESE TWO PINS In general an oscilloscope is not accurate enough to use in setting the excitation voltage use a good voltmeter 3 Plug the NL108A module into the rack with the power OFF leaving several empty bays to the left of the module so that the trimpot marked set bridge voltage can be adjusted DO NOT CONNECT THE PRESSURE TRANSDUCER YET 4 Switch on the NL900 rack and adjust the set bridge voltage trimmer to give the correct excitation voltage at the bridge voltage
70. ass into the NL254 input via the rear edge connections Both jumpers are factory set for no communication via the rear edge connections Specification Summary Input IN 0Q 5V trigger 15V max Min rate 0 1 pom Max rate 999 pps Rate is measured between the rising edges of the input waveform Input from front panel socket or rear connection jumper selectable Output OUT 0 5Vor0 10V 5 proportional to rate latency to output voltage lt o00us Output LIMIT TTL high 5V if the rate is outside the window set by the user otherwise TTL low latency to limit lt 500us Mode Switch Control 4 Position Rotary Switch determining frequency range PPS 000 to 999 pps LO PPS 00 0 to 99 9 pps PPM 000 to 999 ppm LO PPM 00 0 to 99 9 ppm Level Control Rotary dial used in conjunction with Set Upper Limit Set Lower Limit and Set Trigger Threshold buttons Set Limit Buttons Three buttons allowing the Lower lt Upper gt and Trigger Threshold 4 levels to be set Visual Indicators 3 Digit Display for rate and level values Trigger Green LED Lower Rate Limit Red LED left Upper Rate Limit Red LED right We reserve the right to alter specifications and price without prior notification First Issued April 2008 Last Revision April 15 2008 Printed September 4 2009 File Reference N Docs Company Manuals NeuroLog NL254 lwp Digitimer Ltd Page 2 of 2 Copyright 2008 E
71. atteries which show only 11V with no load are beginning to fail The best test however is to check battery voltages under the appropriate load conditions This can be accomplished with the NL510A connected NL800A Power switched on and the output terminals of the NL800A shorted Each battery is checked at the test points with an oscilloscope Seriously discharged batteries will show a marked fall in voltage during each Stimulus pulse which should be at least 1 second duration if a meter is being used Whether this voltage drop will affect the output current depends on the desired output current and load resistance as discussed in the previous section Digitimer Ltd Page 6 of 8 Copyright 2007 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL800A Calibration and Set up Fig NL800A 4 shows three output calibration curves for the NL800A driven by an NL510A Pulse Buffer The NL510A contains on its printed circuit board an adjustable trim pot the one with the knob for setting the output offset The three curves in Fig NL800A 4 were obtained with three settings of the NL510A trimmer The NL510A can be adjusted so that the NL800A is maximally linear curve A but has a small output pulse 3 of the full scale output when the NL510A AMPLITUDE dial reads 0 00 Curve B shows the output relation if the NL510A trimmer is adjusted for a zero NL800A output with a
72. cable to the Headstage should fail there is a possibility of current flowing though the preparation to ground causing an inadvertent lesion This is limited by the design to approximately 650UA Should this be a problem and it is a remote possibility please contact Digitimer for advice ALSO make certain that the NL900 power switch is on before connecting the preparation to the active inputs of the NL100AK or NL104A Do NOT switch the NL900A power on or off while a preparation is connected to the NeuroLog System Do NOT attempt to use oversize plugs with the headstage sockets as pins greater then 1 00 2 00mm diameter will damage the socket NOTE if the NL100AK is required to plug into the NL103 amplifier which is fitted with an input socket without locating keyway the NL100A first stage should be ordered to ensure that the correct mating plug is fitted to the connecting cable 1 Recording of Brain Potentials with FET Circuits Hazard of Inadvertent Lesions by J A W M Weijnen and N Chedhade in Brain Research Bulletin Vol 18 p61 7 618 Specification Input resistance 10 ohms Gain 1 0 Input noise lt 2 UV peak to peak with inputs shorted lt 25 UV for a typical tungsten microelectrode in saline lt 30 UV with a 1 Megohm resistor between inputs bandwidth in all three cases 10Hz to 10kKHz First Issued before July 1984 Last Revision January 12 1999 Printed January 12 1999 File Reference N DOCS C
73. ck Mute circuit that can be set by means of a board mounted trimmer control for between approx 2 and 12ms or by a logic signal of the required period to override the internal pulse generator The design is implemented using low noise active linear circuitry and does not suffer any of the aliasing problems that are encountered when cheaper methods are used The output is provided via a 8 pole front panel socket for which the matching plug is supplied and the module has an internally pre set gain of x5 which can be factory changed Specification Summary Input voltage range Input impedance Filter settings 3dB Low Pass Time constant Cut off accuracy Gain before cut off Attn beyond cut off Crosstalk Noise Deblock input function duration Output DC offset Output voltage range Output impedance 15V max 2V operating with gain of x5 1M 3 LP 3 Time constant HP 30 100 300 Hz 0 1 1 10s 1 6 0 16 0 016HZ 5 5 0 2 20dB decade 6dB octave better than 60dB lt 100uV rms RTI TTL compatible 15V maximum ve edge triggered or external width 2 12ms internally set or external duration lt 10mV 10V lt 6006 Rear connections to the motherboard allow interconnections for channels 1 to 4 This allows connection to the outputs of newer NL820s and the inputs of a NL530 modules without the need of front panel cables NB This module must NOT be placed adjacent to a Counter modu
74. d 15V each of which is completely protected against excessive load with its own internal current fold over circuit which can sustain an indefinitely long short circuit Each of the supplies is also protected by fuses fitted to the rear panel which protect the power transformer against a gradually applied 250V 5 x 20mm overload A suddenly applied overload may not blow a fuse before the fold over protection circuit acts Fuse Ref Fuse Value and speed F3 amp F4 T2AL The indicator light on the case front panel is illuminated when all three power supplies in the power unit are operating with correct output voltages If the indicator does not light when the mains power is switched on POWER switch on the front panel either one of the supplies is faulty or an overload condition exists A module malfunction or faulty circuits constructed on the NL50 Blank Modules may be the source of the excessive power unit load Identify and remove the overload if the indicator is still unlit check the fuses Support Feet To raise the front of the unit when it is mounted on a bench top the front feet can be lowered This is done by lifting the front of the case up and pulling down the leg We reserve the right to alter specifications and price without prior notification First Issued May 15 2002 Last Revision September 27 2005 Printed October 13 2005 File Reference N Docs Company Manuals NeuroLog NL905 lwp Digitimer Ltd Page 2 o
75. design is implemented using low noise active linear circuitry and does not suffer any of the aliasing problems that are encountered when cheaper methods are used The LF CUT High pass filter has a rotary switch that selects the 4 frequency settings and a continuous calibrated control gives adjustment over that range This gives a wide range with 12dB octave 40dB decade attenuation below the selected frequency value The DC switch position by passes the filter sections completely The HF CUT Low pass filter has a rotary switch that selects the 4 frequency settings and a continuous calibrated control gives adjustment over that range This gives a wide range with 12dB octave 40dB decade attenuation above the selected frequency value The WB wide band switch position by passes the filter sections completely In the photograph the LF CUT is set with a Range maximum of 500Hz and the calibrated control is set to 10 giving a filter cut off frequency of 100Hz The NOTCH filter is also IN enabled The HF CUT is set with a Range maximum of 5kHz and the calibrated control is set to approximately 20 giving a filter cut off frequency of 2kHz Specification Summary Input voltage range 10V Input impedance gt 56k ohms Low frequency cut off range DC 0 5Hz gt 5kHz continuously adjustable High frequency cut off range wide band gt 50kHZz and 5Hz to 50kHz continuously adjustable Gain within pass band
76. dial reading of 0 00 Some applications favour the maximally linear calibration others the zero in Zero out adjustment Curve C if Fig NL800A 4 shows incorrect adjustment of the NL510A trim pot It is recommended that the user plot a calibration curve for the NL510A NL800A combination by measuring the voltage induced in a 1kohms resistor placed across the NL800A output With the NL800A RANGE switch on the 100A range 100A will correspond to 100mV across the resistor Because the NL800A is an isolated current source NL800A s can be operated in parallel never in series Thus current stimuli can be summed either with the same sign or with the opposite sign if bipolar stimuli are desired A single NL510A will drive up to two NL800A s in parallel if stimuli with identical timing are desired see the NL512 Biphasic Pulse Buffer module for using two NL800A to produce Bipolar Stimulation STIMULUS ISOLATOR OUTPUT PULSE BUFFER AMPLITUDE SETTING Fig NL800A 4 Graph showing the NL800A Output Current verses NL510A setting Digitimer Ltd Page 7 of 8 Copyright 2007 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual Specification Input requirements Input Connector Output current range Output Connectors Output risetime Output resistance Input output capacitive coupling Accuracy and linearity Dimensions Weight Accessories Supplied Accessories Available Batterie
77. e fitted to the NL9OOD if you wish to mount the unit in a 19 rack To fit these brackets you should locate the two recessed screws on each side of the rack near the front You should now decide which bracket is going on each side by offering up the bracket to the two screws to see if they align The existing screws should be used to retain the bracket and an Allan key is supplied with the brackets to remove and refit the screws When the brackets are fitted ensure that the screws are fully tightened as they carry the weight of the whole unit when it is in the rack Support Feet To raise the front of the unit when it is mounted on a bench top the front feet can be lowered This is done by lifting the front of the case up by about 75mm and pulling down the leg When fitted into a 19 rack you may wish to remove these feet totally This is done by removing the rubber feet that would normally rest on a bench then removing the screw that is fitted into the recess The nut is fixed to the bottom plate and will not become loose The feet should be kept safely in case they are needed later History The NL9OOD is the latest in a long line of NL900 models The design changes over the years have been due to unavailability of parts or specification changes BUT all modules ever made will fit and work in all racks ever produced The different models can be identified from the Serial Number label and usually the printing on
78. e polarization potentials up to 500mV and behave like capacitors in parallel with a very large resistance ie 200 500Mohms they are not often used for DC measurements When the NL102G is used for low noise AC coupled measurements e g extracellular recordings through tungsten microelectrodes it is advisable to connect a large value resistor ie 50Mohms between the In input and the ground This resistor does not degrade the recording characteristics of such electrodes but eliminates the large unstable junction potentials which may saturate the NL102G input The User must supply a suitable indifferent electrode the nature of this electrode will depend on the sort of recording electrodes used fe al Xi OUTPUT r _ 0 Meir l OPTIONAL L tbl GUARD e X10 CONNECTION OUTPUT L gt j l INJECT i l 4 CURRENT ELECTRODE RRENT ni SET CURRENT CELL I a ae 7 ANDPOLARITY PREPARATION i j TTL ig GATE RRENT l CURRENT oe eee l CONTROL INDIFFERENT INJECTION IXPLTS ELECTRODE r om ANALOG J i d L Es IMPEDENCE CHECK CALIB TTL GATE SYSTEM DIAGRAM Limye Fig NL102G 2 NL102G System Diagram DC Level The DC level adjustment control on the left hand panel provides a means of backing off DC voltage present at the electrodes It operates between the x1 output of the pre amplifier and x10 amplifier The x1 output is therefore alwa
79. e pre amplifier modules Optional Accessories NL969P 9 way plug to mate with NL820A As used on NL822 and NL824 leads NL969S 9 way socket to mate with NL822 and NL824 As used on NL820A front panel NL969T T adaptor connects 2 x NL822 into a NL820A for 4 channel use Digitimer Ltd Page 4 of 5 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL820A ISOLATOR FILTER CONDITIONER NL820 NL135 NL530 oO 500 7 ns 200 a ue 1 1 OO 0 20 10 Signal Input From Remote Amplifier h OO 2 A System Drawing Complete 4 channel system for isolating filtering and conditioning amplified input signals No other leads are necessary as connections are made bv the rear connectors Last Revision March 4 1998 File Reference NADOCS COMPANY MANUALS NEUROLOG NL820A SAM Digitimer Ltd Page 5 of 5 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com NL844 4 channel Remote Pre Amplifier Introduction The NL844 is a small four channel low noise high impedance differential pre amplifier designed for use close to the preparation or human subject The unit is intended for use with the NL820A Isolator from the NeuroLog system and used this way complies with BS EN 60601 for patient safety to class I type BF It has controls for LF c
80. e stimulation site and the recording site A physically large COM electrode can stop surface conduction of the stimulus to the recording electrodes Digitimer Ltd Page 2 of 5 Copyright 1996 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL844 Rear Panel The rear panel contains the toggle switches for the control of channel enable on off LF cut and gain controlled in blocks of two channels 30Hz x100 a 10HZ EL 3Hz x10k 30Hz x100 CH Kai ENN w 10Hz ns x1k a4 4 3Hz x10k Digitimer Ltd LF Cut Gain LL refer to manual before use The left hand side of the Rear Panel of the NL844 showing the controls for Impedance Check Channel Enable LF cut and Gain Also the power LED The cable connection to the NL820A is off to the right hand side Switch function from the left Impedance Check Up VE Impedance checking of the ve non inverting inputs Centre OFF Impedance checking off as required whilst recording Down VE Impedance checking of the ve inverting inputs Active Channels upper switch described lower switch is the same but for Channels 3 amp 4 Up CH1 Channel 1 is on enabled Channel 2 is off Centre OFF Channels 1 and 2 are both off Down CH1 2 Channel 1 and 2 are enabled for recording LF Cut upper switch described lower switch is the same but for Channels 3 amp 4 Up
81. e supplied Older NL104A s may have used Imperial 4BA screws which should be discarded Step 1 Unsolder and move the front end screen up the NL104A by about 10mm to allow the lower bracket to pass it Step 2 Ensure that the NL104A Gain switch does NOT have a PCB fitted to its rear If it does this switch needs replacing with one similar to that shown Step 3 Solder the supplied 1mm socket to the leg of the middle of three resistors as shown Ensure that the joint is secure and is not touching either of the other two resistors Page 3 of 5 Copyright 2000 2006 Digitimer Ltd Tel 44 0 1707 328347 Fax 373153 Website www digitimer com E mail sales digitimer com Users Manual NeuroLog System NL104F Fitting the NL104F to an earlier NL104A page 2 ao Sd py i Li PrE SSeeiag ge a y E E F A F Fi E a a Ents BS Ete oT he E E E ogavraea os ot a Step 4 Remove the IC and connect the ribbon cable as shown Also plug the 1mm pin shown on black wire into the 1mm socket fitted above Ensure that the HF filter jumper is in the required position as later movement is tricky 2 washers in both positions Step 5 Fit the NL104F to the NL104A using the screws provided On the NL104F ensure that there are two plain washers between the PCB and the panel lug If the NL104A had two plain washers between the PCB and panel lug ensure that the
82. e supplied on its own or combined with our NL109 Bridge Amplifier When ordering please use part code NL61 xxx where xxx should be replaced by the correct range available range options are given below Specification Range FSO 25g 55g 110g 220g 450g 1000g 1500g 10z 202 402 80z 180z 3602 540z Output Sensitivity AmV V nominally Accurac lt 0 3 FSO Excitation Voltage 5vdc recommended 10vdc maximum Bridge Resistance 25g 55g 450g nominally 7250 110g 220g 1000g 1500g nominally 10000 Insulation Resistance gt 100MQ at 50vdec Operating Temperature Range 40 C to 80 C z 10 C to 60 C lt 0 05 FSO C lt 0 05 FSO C Environmental Protection Level Deflection lt 0 03mm Connection Type Via 4off PTFE insulated solder terminals Pin A Signal Pin B Excitation Pin C Signal Pin D Excitation 34 Mechanical P 18 f 3 4off mounting s Dimensions f a14 p holes 3 2 All dimensions in 4off solder terminals for sensor signal milllmeters connections l 4 57 Yy E i 19 FORCE 1 2 M2 X 0 4mm actuator rod 24 supplied with 2off lock nuts Ze First Issued January 29 2013 Last Revision January 29 2013 Printed January 29 2013 File Reference N Docs Company Manuals NeuroLog NL61 odt Digitimer Ltd Page 1 of 1 Copyright 2013 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users
83. e switch is in the left position the signals passing through the module will remain unaltered while the External Trigger Input Socket has a TTL low input When the External Trigger Input Socket input goes TTL high the Signal outputs will be attenuated inverted according to the PCB switch settings ALT GAIN Signal inversion attenuation can be gated on and off in response to a logic signal at the external trigger input With the External Source Selector set to the left the C B decs TET EO signals will remain Normal x1 gain input polarity i i while the External Trigger Input is TTL low When this inputs goes TTL high the signals will be attenuated inverted As above the LED will illuminate O ene A eee i when the output signals are in the altered state Internal Switches amp Jumpers Each channel has a sliding selector switch which is used to set the alternative gain for that output channel The slider switch has 8 numbered positions with the switch positions and respective gains indicated on the PCB 1 x 50 5 x 10 2 x 20 6 x 20 3 x 10 7 x 50 4 x0 8 x 100 Each channel also includes a blue jumper which is used to allow input signals to pass from module immediately to the left through the rear connections on the PCB rather than the front panel sockets As with our other modules the rear connection is enabled by linking the two jumper pins as shown in the photographs below If front panel cable conn
84. ections are to be used as the signal inputs then the blue jumper should be removed and re positioned on only one pin for safe storage ay wane a E M a M H m ar Cai T ty IH NL540 PCB View Zoomed view of Channel 1 Switches and Jumper Specification Summary INPUTS Signal Input Voltage Range 15V External Trigger Input Requirements TTL triggered on ve edge of gt 500ns pulse Input DC Offset Control 0 6V independent for each channel OUTPUTS Gain Internally selectable for each channel x 50 x 20 x 10 x 0 x 10 x 20 x 50 x 100 Signal Output Range 15V front panel sockets or rear connections Rear PCB connections to the motherboard allow input jumper selectable and output permanent interconnection between this and other modules without the need for front panel cables Users Manual NeuroLog System NL601 NL601 Pulse Integrator PULSE INTEG NL601 ON FULL SCALE COUNT 255 OFF RESET 25 500 INT RESET EXT RESET EXT RESET LATCH PULSE ANALOG OUT OUT ADJ IN RESET LATCH IN Specifications Inputs Level Input Reset Latch Pre scalar Outputs Pulse out Analogue out Steps levels First Issued before July 1984 Introduction The NL601 PULSE INTEGRATOR has a digital counter which produces an analogue output proportional to the count A pulse at the input socket increments the counter towards a full scale count
85. ed ve supply Blue ve signal Green ve signal Yellow Options Available Consult Factory Many Options and special versions available Mechanical Dimensions All dimensions in milllmeters 2 2 holes 6 2 M6 x through First Issued January 29 2013 Last Revision January 30 2013 Printed January 30 2013 File Reference N Docs Company Manuals NeuroLog NL62 odt Digitimer Ltd Page 1 of 1 Copyright 2013 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL63 NL63 Aluminium Medium Range Single Point Load Cell Introduction The NL63 is a medium range anodised aluminium alloy single point load cell which has been specifically deigned for platform weighing applications although it is equally suited to other weighing and force measurement applications where high accuracy Is required The NL63 is suitable for use in platforms with sizes up to 400mm x 400mm It is environmentally sealed as standard to IP66 The NL63 series can be supplied on its own or combined with our NL109 Bridge Amplifier to provide a complete load monitoring system When ordering please use part code NL63 xx replacing xx with the required range from those given below Features Ranges 50 100 150 200 250kg Anodised aluminium construction Environmentally sealed to IP66 High accuracy lt 0 02 Suitable for use in platforms maximum si
86. ers Manual NeuroLog System NL405 Delayed Output Pulse Duration Jumpers on board Delayed Output Pulse Duration NL405 Component View of PCB Delayed Output Pulse Duration Selection The Duration of the pulse at DELAYED OUT can be set to one of six 6 pulse durations and is set by two jumpers on the PCB These are altered by pulling them off their pins moving them to where is required and pushing them back on Both jumpers MUST be fitted in one of the six configurations shown below We reserve the right to alter specifications and price without prior notification First Issued December 19 2002 Last Revision March 26 2003 Printed March 26 2003 File Reference N Docs Company Manuals NeuroLog NL405 02 lwp Digitimer Ltd Page 5 of 5 Copyright 2003 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL410 NL410 Calibrator CALIBRATOR NL410 Specification Trigger level Trigger Input Limit Trigger Input Impedance Output Level Output Level Accuracy Output Pulse Duration Pulse Duration Accuracy Polarity Output Impedance Output Isolation Introduction The NL410CALIBRATOR can be used for the precise calibration of the gain of an amplifier system for adding a pulse of accurate amplitude and duration to a recording trace The output of the Calibrator is isolated allowing for the user to choose the best method of
87. ersist when the NeuroLog System is powered off Seiting the Output Voltage Range Pressing and holding the SET TRIGGER THRESHOLD button for 2 seconds will result in the 3 digit display flashing and displaying the current output voltage setting of either 00 5 for 5V or 01 0 for 10V Turning the LEVEL CONTROL dial while the display is flashing will switch between these two settings Once the desired output voltage setting is displayed the setting can be stored by pressing the upper gt or lower lt threshold limit buttons The output voltage setting persists when the NeuroLog System is powered off Should either the Trigger Threshold Output Voltage or Upper Lower Limit values become corrupted after restoring power the Upper Lower Limit LED indicator will flash to alert the user that they need re entering Rear Connections and Jumpers The rear edge connector in the NeuroLog Rack allows adjacent modules to be connected together without the need of external front panel leads Digitimer Ltd Page 1 of 2 Copyright 2008 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL254 OUTPUT The upper jumper in the top corner of the NL254 printed circuit board allows either the OUTPUT or LIMIT outputs to pass to the module on the immediate right via the rear edge connections INPUT The lower jumper allows the output from the module to the immediate left to p
88. es digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL120S NL120S Audio Amplifier AUDIO AMP Introduction ni NL120 The NL120S Audio Amplifier is a power amplifier for driving a 4 or 8 ohm loudspeaker such as the NL985 It has sufficient power amplification to raise a B 1 20mV signal to a moderate sound level The module features an input selector for switching between two input signals and the options of amplifying only positive or negative peaks useful when baseline noise masks the sounds of nerve spikes n of interest The output is shaped to improve the low frequency response of small OFF loudspeakers and is power limited to minimize the nuisance caused by large transients such as shock artifacts THRESHOLD Fig NL120S 1 illustrates the operation of the THRESHOLD potentiometer and the mode toggle switch The threshold levels and a typical input waveform are shown at the top Large voltage excursions are clipped symmetrically about the baseline at the internal power limit whatever the toggle switch setting With the toggle switch in the middle position the output is the amplified input waveform shown at the bottom of the figure un distorted except for the power limit clipping Power limiting protects small loudspeakers as well as ears from amplified shock artefacts etc which can be an order of magnitude larger than the signals of interest in some recordings
89. essure minus the mean physiological pressure TUTE being monitored The flush device aiso incorporates HE ees Es a te an overpressure Safety valve to prevent the pressure i 3 transducer from exceeding approximately 7000 Figure 3 Transducer interface Cable Connection miitg The overpressure safety valve vents the excess fluid safely back into the infusion bag while maintaining a sealed sterile pathway CAUTION Another DTX Plus model DT NN incorporates the Disposable transducers offer a single made of 30 cc nr flush device for neonatal applications electrical isolation through a diaphragm air gap Separate instructions for neonatal kits will be found in insulation gel or same combination of the above those product packages and are not recommended for use with non tM je laantinall eat isolated patient monitors If you are in doubt eS S den oai ane lol ietiee specMicatons about about the isolation characteristics of your to our original D7X transducer and utilizes the same reusable accessories including the monitor interface rae ea old a Service manual or cable and mounting brackets Two distinguishing call the monitor manulacturer features will be noticed 1 The IV administration set is now preconnected Zeroing and Calibration directly to the transducer for easier setup 1 Zero balance the system to atmospheric pressure 2 The flush actuator lever of the original D7X has and calibrate the transducer according t
90. et provides a short duration pulse set internally that is produced at the end of the timed WIDTH pulse This provides a trigger out after the set Delay time The NL405 can be used for digital control of pulse duration or for introduction of a delay to a trigger pulse The logarithmic or exponential nature of the many biological responses make the very wide continuous adjustment from us to minutes particularly beneficial Specification Summary Input TTL pulse Input is 1 TTL load Trigger edge Positive or Negative selected from front panel Manual Push button operation on push Output Width TTL Output will drive 10 loads Polarity Both active high and active low sockets Range 1 us to 999 s Control 001 to 999 Multiplier 1 us 10 us 100 us 1 ms 10 ms 100 ms 1s Accuracy gt 0 5 Delay from Trigger In gt lt 200ns Indicator Amber LED on for approximately 100 ms for each pulse Output Delay TTL Output will drive 10 loads Polarity Active high Duration 0 5 us 1 5 us 5 us 20 50 us 150 us 500 us 10 by on board jumpers Output Mode Fixed Width or Re Triggered selected from front panel Reset Inhibit 450 ms 420 after change of rotary range control Rear connections to the motherboard allow Input and Output interconnections between this and other logic modules without the need of front panel cables Digitimer Ltd Page 1 of 5 Copyright 2003 E mail sales digitimer com Te
91. f 2 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System ACCESSORIES Accessories Introduction To enable the user to make full use of the NeuroLog System we make available a wide range of accessories at least some will be required for each and every system No accessory leads or connectors are supplied with the modules of the NeuroLog System unless otherwise stated Usually at least one type NL962 plug or appropriate lead is required for each module ordered Cables NL951 Cables with male connectors Lemo type F00250 on both ends available in 5 standard lengths 15cm 30cm 45cm 1m 2m When ordering please specify length e g NL951 45cm NL952 2m cable with a male connector FO0250 at one end and tinned leads at the other NL953 2m cable with a Lemo type F0304 male connector one end and tinned leads at the other end mates with the input socket on the NL103 AC Preamplifier superceded by NL104A and NL107 Recorder Amplifier NL953K 2m cable with a Lemo type FGOB304 male connector one end and tinned leads at the other end mates with the input socket on the NL104A AC Preamplifier and NL108 Pressure Amplifier NL975 1m screened cable with tinned leads at one end and two 4mm plugs at the other mates with NL120 Audio Amplifier output socket Extension Cables NL950 10cm cable with male connector Lemo type F00250 one end and
92. ght 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL301 Jumpers JMP1 JU g iU L J 10 NL301 COMPONENT VIEW LK3 Fig NL301 2 On board jumpers LK2 Range Select Jumper these pins together to reduce the front panel range by a factor of 10 LK3 First Gate Pulse Jumper these pins together to enable a pulse coincident with the start of the Gate JMP1 Rear Input Jumper the two gold sockets to source the GATE signal from the output of the module on the immediate left Last Revision March 4 1998 File Reference NADOCS COMPANY MANUALS NEUROLOG NL301 SAM Digitimer Ltd Page 3 of 3 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL304 NL304 PERIOD GENERATOR PERIOD GEN NL304 PERIOD 10ms AO0Oms Specification Output Period accuracy Period range Period Multiplier Output pulse width GATE IN OUT RESET Introduction The NL304 PERIOD GENERATOR contains a crystal oscillator and frequency dividers for producing a precise stable frequency standard It can be externally gated GATE IN and synchronised with an external source RESET input The pulse train can be switched off and a single output pulse can be produced manually by a front panel push switch The NL304 is the basic clock of the
93. ginjeredura Bupeado 0F 92 02 PUBLSHI AA IMIENIA PEO WIIG Og SOI Lupe PUDIANI DOP ZHON SV AOZ aT yz 0102 JO WUBIN EOI BUELL te Qfyuwe oF AWANISUSS jO JUANI BUSY O eTOF ASL JO vOntONT We por Se 18 Spy A AriC yo adore y Juan pur az yano ouy yira B toy THEW St MOAMUDT AN FERUT JO ALIpRal al JO g7 uey alou OU AG MYE DONAHEA ATANIEUSR pure SENOSAY Ateo SUOHEVEA AIAISUES PLE SISGIAS Y UO IG Saaja PIO aij OF anp WONULAGP Unuy AIL A B3UI UB 01 OND ADBINIIBU WNUHXE uN UAU pp F j88 0 0197 ZHAG or dn wawixew Syy ay 40 AGEDA VORPIDA muwon wyo HCE suasa Inding eLRMOU MC NHOO L apunisigas ndug JASI BOP Beraungo Fot uw BOURIIOL GuNSseid s8A Hy jus ODE 01 HUD oO P UEI QINSSasd Rey rig AN RA Kem ie 2 g n Ba th ee k h vibe me ne af by t psu pi U A Za 7 ane Eo CE SOSA gess SATA NAS Se HERON LES ET Re See aa on hy Let eee a lt Users Manual NeuroLog System NL109 NL109 Bridge Amplifier SCN Introduction NL109 ZERO The NL109 BRIDGE AMPLIFIER is DC coupled differential amplifier intended for use Os with transducers which require a bridge excitation voltage including our own force transducers NL61 NL62 and NL698 It can also accept our NL100AK Headstage for DC coupled microelectrode recordings The output from the NL109 is the amplified and 50 ff filtered difference between the IN and IN signals
94. gnals can be disconnected from the outputs of the module on the immediate left if they are inappropriate This is done by removing one of the jumpers in the lower rear corner of the PCB for each channel to be disconnected The jumpers can be parked so that they are not lost by placing them on just one of the pins as shown for channel 1 We reserve the right to alter specifications and price without prior notification Digitimer Ltd Page 2 of 3 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL134 135 136 ISOLATOR FILTER CONDITIONER NL820 NL135 NL530 o ee 500 E _ ce 200 1K 100 2K 1 1 20 Signal Input From Remote Amplifier IN s Recording OO Q O 0 A 09 090 nigeria So System Drawing Complete 4 channel system for isolating filtering and conditioning amplified input signals No other leads are necessary as connections are made by the rear connectors Last Revision March 4 1998 File Reference N DOCS COMPANY MANUALS NEUROLOG NL134 6 SAM Digitimer Ltd Page 3 of 3 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL144 NL144 Filter 4 channel FILTER Introduction NL144 The NL144 FILTER is a 4 channel second order two pole high pass filter module I
95. had passed through the Lower level and a Timed mode If it had not passed through the Upper level by the end of the LOWER output pulse 200 micro second b No Upper mode Passes back through Lower without crossing the Upper level this is without time constraint Normal position Digitimer Ltd Page 3 of 6 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL201 Rear Connections and Jumpers The rear edge connector in the NL900 rack allows adjacent modules to be connected together without the need of front panel leads Full details are giving the Jumpers section INPUT The input signal can be disconnected from the output of the module on the immediate left if it is inappropriate OUTPUT The user has the choice of one of three output signals that can be connected to the rear connector for automatic routing to the module on the immediate right Multiplexer Frequency The internal multiplexer oscillator runs at a frequency of approximately 150kHz a 6 67us cycle and can be measured at pin 2 of ICY This oscillator is used to switch between the display of the Upper level Signal Lower level and Signal again in a 1 7 1 7 6 67us 46 7us 6 67us 46 7us time frame If it is required to slow down this oscillator the value of C19 should be increased proportionally see Fig 201 3 The standard value of C19 is 0 015uF 15nF and a va
96. he base is fitted with rubberised feet and the front pair may be extended so as to raise the front of the unit The NL905 case has an integral module retention system consisting of a simple slide action lever on the power supply panel Thus fittings such as retained screws D Locks etc on individual module front panels are unnecessary this simplifies the modules mechanical design reduces their cost and greatly improves the ease with which rapid changes in module arrangements can be made The NL905 power supply produces three voltages 15V 5V and 15V stabilised against line and load variations The voltage outputs are rated at 1A and all three supplies have internal fold over current limiting In addition the supplies are protected with rear panel fuses Each supply has less than 50mV line ripple at maximum load A feature of the intergral NeuroLog System power supply is a built in monitoring circuit which indicates by extinguishing the power supply indicator on the front panel excessive loading of one or more of the three supply outputs While it is expected that a power supply failure will never occur using genuine NeuroLog modules the fault indication is invaluable when testing custom circuits built in the NL50 Blank Module The NeuroLog System Case is the heart of the NeuroLog system being the rack to house the modules as well as providing the power for them to function It also has an interconnection system unique to the
97. her for an input gain of x10 LK3 Multiplexer display Jumper the pins together for a display of the threshold levels with the signal at the MONITOR socket LK4 Gate pulse occurrence The GATE pulse will occur after the input signal has passed through the Lower level from OV and Timed mode Jumper lower two pins of link LK4 If it had not passed through the Upper level by the end of the LOWER output pulse 200 micro second No Upper mode Jumper upper two pins of link LK4 Passes back through Lower without crossing the Upper level this is without time constraint Normal position JMP1 Rear Input Jumper the two gold sockets to source the INPUT signal from the output of the module on the immediate left JMP2 Rear Output This selects the OUTPUT of this module for rear connection to the input of the module to the immediate right Jumper one of the following to the central socket as follows Upper socket for LOWER signal Middle socket for UPPER signal Lower socket for GATE signal Last Revision September 30 1998 File Reference N DOCS COMPANY MANUALS NEUROLOG NL201 SAM Digitimer Ltd Page 6 of 6 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL202 NL202 AC Signal Delay Introduction The NL202 AC SIGNAL DELAY is an analog signal delay unit utilizing a bucket brigade delay line providing a low
98. hin the NL501 so that they can both be applied to one of our stimulus isolators In this way a pair of stimulation pulses can be given to a preparation to study phenomena such as paired pulse facilitation Although the illustration shows an NL301 Pulse Generator initiating the stimuli at a certain frequency the initiation pulse can come from any external device capable of producing a TTL compatible logic pulse It is also possible to replace the NL301 with the NL304 Period Generator if slower frequencies are required however because the NL304 only produces a 0 5us output pulse it would be necessary to employ an extra NL405 after the NL501 Logic Gate in order to widen the output pulse so that it could effectively trigger the DS2A or DS3 stimulator Frequency set to 1Hz by NL301 with internal jumper set for 0 05 120Hz range User controlled delayed pulse from NL405 set to 10 x 10ms Non delayed and delayed pulses combined at the NL501 Logic Gate internally set to OR Application Note 21 Dig NeuroLog System SYSTEM Using the NeuroLog System for Cardiac Pacing and Studies of Effective Refractory Period PULSE GEN WIDTH DELAY LOGIC GATES NL501 n D i a B 1 amp OUT GATE 1 OS S 4 m N O Os OE DS3 Current Stimulator with pulse duration amplitude and polarity control 1s pulse interval i e 1Hz set by NL301 10th Pulse passed B b
99. ight 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NeuroLog System Basics Logic Signals As TTL is a binary system each TTL input or output must be within one of two narrowly defined voltage ranges unlike analogue inputs or outputs which can vary continuously between specified limits A binary 1 or logic high in TTL has a voltage range between 2 4V and 5 0V a binary O or logic low occupies the range between 0 0V and 0 8V A TTL output provides a low resistance shunt to ground typically 220 to 300 ohms when it is at logic low i e O to 0 8V level Other pulse sources such as non T TL signal generators may not provide this current sinking path to ground and therefore may require some modification in order to be used to drive TTL inputs The scheme illustrated below will work for a variety of positive pulse trains gt gt To TTL Logic Pulses In 3309 Input Fig NL Basics 1 The value of R depends on the nature of the circuit or instruments providing the positive pulses The maximum voltage at the TTL input must not exceed 5 5V but must be at least 2 4V at logic high levels and the rise times of the pulses at the TTL input must be fast typically less than 100nsec Thus if the positive pulses have a 12V amplitude R x330 ohm 390 ohm or 1kohm maximum for 3V logic level Check that the resistor network i
100. imer com Page 1 of 1 Tel 44 0 1707 328347 Fax 373153 Copyright 1996 9 Website www digitimer com Users Manual NeuroLog System NL603 NL603 COUNTER amp Divider COUNTER RESET NL603 R N IN Q RESET Zo Specification Summary Inputs Output fan out Introduction The NL603 COUNTER is a two decade counter incorporating a display It can function in three different modes to give counting gating of an external pulse generator or division of an input frequency The unit has a GATE input as well as a RESET to allow electrical control Multiple units may be combined for higher count or resolution The three modes are FREE RUN Counter The display shows the count of the input signal PRESET STOP Comparitor This can be used to GATE an oscillator PRESET RESET Freq Divider There will be 1 pulse out for each n pulses in A brief logic pulse at the RESET input causes the counter to reset to 00 the NL603 will remain at 00 as long as the input to RESET is high If no connection is made to the GATE input the counter counts each IN pulse An externally applied low logic level to the GATE input inhibits the count the counter responds to each IN pulse when the GATE input is high The following timing diagram illustrates the operation of the NL603 COUNTER TTL pulses 10 TTL inputs Output pulse width 0 5 us nom FREE RUN amp PRESET RESET modes Output High
101. imise interference and pick up The rise times of TTL pulses are much faster a few nanoseconds than those produced by equipment found in the past in Physiology Laboratories and greater care must be taken to preserve clean signals Patching with fine unscreened wire pushed into input and output sockets for example is unsatisfactory Accessories Only micro miniature coaxial connectors with a Snap on action are used in the NeuroLog System eliminating the nuisances caused by connectors such as the BNC and UHF types which have a twist on or screw on action All external connections between modules are made through miniature screened coaxial cable which reduces cross talk and transient pick up as well as eliminating the rat s nests of fine unscreened wires and 1mm 2mm or 4mm plugs frequently used for patching in other modular systems A variety of assembled cables plugs sockets BNC to NeuroLog adaptors and T connectors are available from Digitimer Ltd and its agents for the NeuroLog system Please refer to our current price list NeuroLog System brochure or the Accessories Section of this manual for further details The connectors are manufac tured by Lemo Switzerland and were chosen because they are the finest micro miniature snap action connec tors available Without these particular plugs and sockets the front pannels of the NeuroLog System would necessarily have been substantially larger This would have reduced the number
102. inal and supply ground is of the order of 100M ohms due to the leakage capacity specified at less than 35 pF Digitimer Ltd Page 3 of 5 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL820A NL8 amp 20A Edge Connector No Function 1 not used on NL820A 2 channel 1 out 3 channel 2 out 4 not used on NL820A 5 channel 3 out 6 not used on NL820A 7 15V 8 keyway 9 OV 10 not used on NL820A 11 channel 4 out 12 5V 13 15V Specification Isolation Voltage 2 500 volts DC or DC plus peak AC Capacitance 35pf Resistance 10k Mohms 10 ohms Ground signal attenuation 2 x signal frequency Hz 10 approx See Fig NL820A 2 for definition of isolation measurements Gain x1 x2 x5 accuracy 3 Input Amplitude 1 volt linear range 10 volts absolute Impedance 10k ohms Bias current less than 50 nA Noise less than 4 mV at 150 kHz Offset less than 10 mV Output Amplitude 5 volts maximum dependant on gain setting Frequency response DC to 15kHz 3dB point Isolated Power 13 volts nominal un regulated current maximum 40 mA output impedance 35 ohms nominal Input Power 15 volts regulated at 45 mA 15 volts at 40 mA 5V at 100uUA from NL900 Add 1 2mA for each 1mA of Isolated power used 15V 93 mA 15V 88 mA 5V 100A for max isolated power specified Refer to NL822 and NL824 data sheets for suitabl
103. ion signal positioned on each trace will result in a Calibration of the overall resulting average Current Injection The set of controls and connectors enclosed by the white lines on the right hand front panel are all concerned with current injection The toggle switch 10 turn potentiometer and TTL GATE IN socket determine one current source the EXT STIM IN socket determines the timing and amplitude of a second source which is added algebraically to the first With no input at the TTL GATE IN socket a current with its amplitude determined by the 10 turn dial flows when the toggle switch is activated up for depolarizing and down for hyperpolarizing current flow With a TTL input the current set on the dial and switch flows when the TTL input is high A signal applied to the EXT STIM IN socket causes a current to flow independently of the toggle switch 10 0V at this input corresponds to 100nA Note that the total amount of current that can be passed even with both sources activated is 100nA The MONITOR OUT shows the total current injected Digitimer Ltd Page 3 of 4 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL102G Depending on jumper selection this can be 100nA 50nA 20nA or 10nA Neutralization The capacity at the input of the headstage can be neutralized by setting the NEUTRALIZATION control Either the IMPED CHECK or C
104. irst Issued before July 1984 Last Revision October 18 2000 Printed October 18 2000 File Reference N DOCS COMPANY MANUALS NEUROLOG NL108A SAM Digitimer Ltd Page 3 of 3 Copyright 1996 2000 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com E m e DADOCSICOMPANY MANUALSINEUROLOG NL108T2 SAM Last Revised January 28 1997 Printed January 29 1997 NL108T2 Disposable Pressure Transducer earth A ppc WELWYN GARDEN CITY j HERTFORDSHIRE Instruction sheet ae ENGLAND Please read before use Tel UK 01707 328347 To connect this transducer to a NL108A Pressure Amplifier use Int 44 1707 328347 a NL108L2 Interface cable see Figure 3 Fax UK 01707 373153 int 44 1707 373153 Please note that the NL108A is NOT an Isolated Transducer aie ssiseacigivnercor internet http Avww digitimer com Amplifier as described below DTX Plus Transducers Transducer Interface Cable Connection the DTX Plus flush model includes an integral 4 Connect transducer to reusable interface cable by flush device that is intended for use in physiological aligning the connector arrows and pushing the pressure Measurements which require continuous connectors together see Figure 3 flow to maintain catheter patency see Figure 2 The flush device delivers a nominal flow rate of 3 cc hr Reusable Cable Connector Jum agf Transducer Connector os a differential ae of 200 mmHg infusion ag pr
105. is not marked below 1 the NL301 will produce an output frequency down to 0 5 This gives a 0 5 12 or 24 1 range on a single control With the three decade toggle switch the total range of 0 5 Hz to 1200 Hz can be covered in three over lapping ranges An internal jumper is fitted to change the 0 5 1200 range to 0 05 120 Hz by changing the board jumper When this jumper LK2 is fitted the range will be 0 05 120 and when removed it will be the marked 0 5 1200 Hz see diagram that follows Single Off Continuous This three way toggle switch allows a single output pulse at the set pulse width when it is pressed into the SINGLE position The switch is biased so that it will not stay in this position In the OFF position there is no output In CONTINUOUS the output can be gated see diagram that follows Gate Function The Front Panel socket allows the NL301 output train to be gated on and off In CONTINUOUS mode the output pulse train will start in synchronism with the positive going edge of the GATE signal and continue until the GATE signal is taken low or the toggle switch is switched out of CONTINUOUS When there is no connection to the GATE socket the NL301 will give a continuous train of pulses when switched to CONTINUOUS Digitimer Ltd Page 1 of 3 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL301 First Pulse Opti
106. itude discriminator for nerve spikes and other events which produces separate output pulse trains for spikes which a cross the Upper voltage threshold b cross the Lower voltage threshold c cross the Lower threshold but not the Upper threshold The WINDOW HEIGHT potentiometer sets the DC level of the window and the APERTURE potentiometer sets the separation between the two voltage thresholds of this window Thus slight changes in signal amplitude require adjustments of only one setting and it is impossible to set the Upper voltage threshold lower than the Lower voltage threshold A front panel switch selects either positive VE or negative VE slope and level triggering and there is an choice of two internally selected input voltage ranges The MONITOR output socket provides a display of the input signal with the Lower and Upper levels super imposed on it to enable easy setting of the discrimination levels This module is essential for converting spike trains which are analogue signals into trains of digital pulses these can be analysed using other modules such as the NL700 LOG DISPLAY or used to synchronise displays trigger averaging etc An internal jumper allows the input to be DC coupled or have a time constant which is appropriate for nerve spikes with rise times less than 200us modifications for longer rise times are available by special order To line up with the front panel markings the input signal should be
107. ive logic pulses into TIL output pulses Two converters are available for each conversion giving a total of four All inputs and outputs being clearly marked on the front panel The negative logic output amplitude is adjustable between approximately 9V and 14 5V by a potentiometer situated in the middle and near the bottom of the printed circuit board SPECIFICATION Output rise and fall times Output drive TTL outputs Output resistance negative logic outputs Output level negative logic outputs lt 1 microsecond up to 10 TIL inputs 3 3k ohms 9V to 14 5V adjustable Digitimer Ltd Page 1 of 1 Copyright c 1990 Users Manual NeuroLog System NL530 NL530 Conditioner 4 channel CONDITIONER NL530 Introduction A single width module designed to give Gain and Offset set up controls when interfacing ee signals to the Analog to Digital Converters ADCs of PCs 1 The module contains four channels each with independently adjustable Filter settings 2 and front panel Gain and Offsets presets There is also a Master ADC offset control to allow Unipolar ADCs to be used with Bipolar signals e360 CAL As ADC boards have a precise input range outside of which damage may occur the 4 module features on board preset controls to set all channels to CLIP or limit at independently set positive and negative or zero levels IN OUT 1 Specifications of each independent channel Input Fro
108. l 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL405 Mode selection TRIGGER in OUTPUT Fixed Width OUTPUT Re Trigger Trigger is ignored Output is re triggered here Fig NL405 1 Modes Fixed Width Re Trigger In FIXED WIDTH mode the NL405 will produce an Output pulse of the duration as specified on the Front Panel regardless of further Trigger applied to the input IN Trigger pulses received during the time the Output OUT is active are ignored In RE TRIGGER mode the Output pulse duration of NL405 is extended when a further trigger pulse is received at the input IN The number of times an output can be extended by re triggering is unlimited Output reset and Inhibit RANGE SWITCH Switch rotated here Trigger ignored as within 450ms of reset TRIGGER in lt WIDTH VO OUTPUT Pal WIDTH reset shortened No Delayed Output Pulse as reset Output Delayed ra Output is reset eral Fig NL405 2 Output reset and Inhibit The Output pulse duration can be terminated early in either mode by rotating the Range control It would be normal in this instance to rotate it to the next click position and then back to where it was set The Outputs are inhibited for 450 ms after the switch becomes still Note that a Delayed Output pulse is NOT generated at the end of a WIDTH that is terminated early
109. l input through which current can be injected The shield socket Shd is the x1 output and may be used as a capacitance ground or shield at the preparation If not required for this purpose it must be left unconnected NB this is a major difference between the NL102 and the NL102G DC Pre Amplifiers The final socket is the system ground Gnd and connection should be made to the preparation via the indifferent electrode DO NOT ATTEMPT TO USE OVERSIZE PLUGS WITH THE HEADSTAGE SOCKETS as pins greater then 1 0mm 2 0mm will damage the sockets Fig NL102G 1 Shown with NL101 Electrode Chamber 2mm plug Chambers are available for the following glass sizes 1 0 1 2 1 5 and 2mm o d Please specify when ordering Electrode Connections Fluid Filled Pipette Electrodes Pipettes can only be attached to the headstage by using an electrode chamber part No NL101 Metal Electrodes Metal electrodes can be connected using a NL04 electrode holder alternatively the user must adapt a 2mm pin connector supplied to suit the particular electrodes used A common solution to this problem is a short length Digitimer Ltd Page 1 of 4 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL102G i e 5 10mm of hypodermic needle tubing soldered to the 2mm pin keep this connection as short as possible for low interference Because metal microelectrodes exhibit larg
110. l proportional to VE Source Impedance Impedance Check with as switch shown Selector switch The signal that can be expected to be seen on a display is similar to this 500mV 500us 33ms 30HZ Note that the 1 7V amplitude is at the Output of the amplifier system If the gain has been set to x2 on the NL820A and x1 000 on the NL844 the signal at the input to the NL844 would be 1 7V 2 000 850uV As the transfer function is 100UV 1kQ this would imply the Source Impedance is 850uV 100uUV 8 5 x 1kQ 8 500 NB This signal has a 6 1 duty cycle as shown and may be upside down from that shown Digitimer Ltd Page 4 of 5 Copyright 1996 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual Specification Summary NeuroLog System NL844 Input signal maximum for linear response AC Differential DC Differential Common Mode Input Impedance Input Connectors Gain Common Mode Rejection Noise Impedance Checking LF cut 3dB HF cut 3dB Deblock Dimensions Weight Cable Accessories Available 20mV 400mV gt 9 5V 100MQ 1 5mm TouchProof DIN 42802 x100 x1000 x10 000 with control of channels in pairs gt 120dB 10Hz gt 110dB 50Hz gt 90dB 1kHz lt 7uUV pk pk lt 1 4uV rms RTI 3Hz 10kHz lt 0 4uV pk pk lt 80nV rms RTI 3Hz 100Hz 1
111. lds and it triggers both LOWER and GATE pulses The peak of the third spike is above the window and it triggers LOWER and UPPER pulses but not a GATE pulse in No Upper mode It does however produce a GATE in Timed mode as the transition between the Lower and Upper level took longer than the 200us nom of the Lower Output Pulse this is not typical of nerve spike activity In this example pulses are triggered by positive going slopes if the POLARITY switch was towards the right ve position the threshold would have been arranged in a mirror image position about the baseline Digitimer Ltd Page 2 of 6 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL201 Threshold setting Fig NL201 2 Fig NL201 2 Threshold setting The NL201 thresholds can be set several ways Fig NL201 2 shows one method The monitoring oscilloscope is triggered externally with the positive going edges of the NL201 LOWER output pulses with a moderately fast sweep speed 50 or 100 micro second per division All spikes which cross the lower threshold will appear on the scope face the vertical origin at the left indicates precisely the actual threshold Two super imposed spikes are shown in Fig NL201 2 one which crossed only the lower threshold and one larger spike which exceeded both thresholds The first method is to use the second channel of an oscilloscope
112. le in the NeuroLog rack We reserve the right to alter specifications and price without prior notification Digitimer Ltd Page 1 of 2 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL118 Rear Connections and jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of front panel leads This module has the output signals of channels 1 to 4 permanently connected to the rear connector for automatic routing to the module on the immediate right The input signals of channels 1 to 4 can be disconnected from the outputs of the module on the immediate left if they are inappropriate This is done by removing one of the jumpers in the rear centre of the PCB for each channel to be disconnected The jumpers can be parked so that they are not lost by placing them on just one of the pins as shown for channel 1 NL118 view of components on pcb Edge Connector INPUT Jumpers Deblock duration Channel 1 shown parked LEC Re Channel 2 a ra lt Channel 3 S Channel 4 SOCKETS PINS Channel 8 Channel 1 Channel 7 Channel 2 Channel3 Channel 6 7 Channel 5 gee Channel 4 User view of output socket Last Revision March 4 1998 File Reference N DOCS COMPANY MANUALS NEUROLOG NL118 SAM Digitimer Ltd Page 2 of 2 Copyright 1996 8 E mail sal
113. led and disabled by setting the black jumper in the upper rear corner upper LH above on the board The jumper has to be pulled from the board rotated to the required position and pushed back into the board sockets Rear Input IN Set the jumper in the upper hole and the one immediately below it GATE Set the jumper in the lower hole and the one immediately above it N C No Connection to the output of the module to the left is set by placing the jumper in the rear hole and the one immediately to the right of it Rear Output This module does not have any On board Jumpers Input Signal Range The Input Signal range is set by placing the one and only jumper on the correct horizontal pair of pins The jumper is in the rear centre LH centre above of the board This is altered by pulling the jumper from the board and placing it on the two appropriate pins We reserve the right to alter specifications and price without prior notification First Issued 1999 Last Revision October 28 2002 Printed October 28 2002 File Reference N Docs Company Manuals NeuroLog NL512 lwp Digitimer Ltd Page 4 of 4 Copyright 1999 2002 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL520 First Issued before July 1984 Last Revision February 12 1990 NL520 CONVERTER The NL520 CONVERTER converts TIL logic pulses into negative logic output pulses and negat
114. les digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL405 NL405 Width Delay Introduction The NL405 WIDTH DELAY is a digitally controlled pulse duration generator and is used to produce precise pulses of adjustable duration with high accuracy and repeatability The NL405 produces TTL logic output pulses of both polarities that have a duration set using three decades of thumbwheels and a seven 7 position range switch It also features a press to start button LED indication of an output and a separate logic output signal at the end of the defined WIDTH time It was designed as a replacement for the NL401 and in most places where the NL403 would have been used The NL405 can be triggered off either positive or negative going edges of the input pulses and the NL405 is capable of 100 duty cycles An external push to make switch can be used when ve edge triggering is selected In the FIXED WIDTH mode the NL405 produces an Output pulse as specified by the front panel controls In the RE TRIGGER mode any valid Input trigger arriving whilst the Output is active will restart the timing and therefore extending the Output pulse duration As long time periods can be generated 999 seconds is over 16 minutes any change in position of the rotary range switch will stop the current Output and inhibit further input triggers for 450 ms The DELAYED Output sock
115. lications such as electromyography EMG or electroencephalography EEG Unlike the NL824 it replaces the NL844 input circuit automatically adjusts to the d c input conditions and features a non linear filter that subsequently modifies its time constant if the differential input signal exceeds its normal 20mV working range Therefore fast short artefacts do not block the subsequent stages resulting in an amplifier with a very fast recovery time from stimulus artefact pulses A de block button is provided to remove any d c offset introduced during electrode placement The rear of the NL844 includes channel selection switches so that any unused channels can be switched off gain x100 xik x10k and low cut off filter 3 10 30Hz toggle switches as well as an impendance checking facility Amplified signals can be filtered through one or more of our dedicated 4 channel filters within the NL134 5 6 amp NL144 FILTER series If further signal conditioning is required prior to acquisition via a computer interface the NL530 CONDITIONER provides additional filtering gain and offset options All connections between the NL820A and these modules can be accomplished through rear panel links removing the need for a large number of interconnecting leads Output to your chosen acquisition system is simply achieved through the use of our NL951B 1m or NL951B 2m Lemo BNC cables one per channel If you are interested in amplifying from 8 or more channe
116. lifiers are supplied complete with connecting cable and matching plug Fig NL820A 1 identifies the pin numbers of the matching plug that is available as Part Number NL969P should you wish to use your own front end Pre Amplifier Pin No Function OONOOAaFRWND Digitimer Ltd Channel 1 Channel 2 Common 13V to Pre Amp 13V to Pre Amp Common Channel 3 Channel 4 Mute to Pre Amp Fig NL820A 1 Outside view of socket amp wiring view of plug Page 1 of 5 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL820A ISOLATION Plug BARRIER Pin Nos IN4 1 O OUT1 gt EEE gt gt IN3 j OUT3 IN4 f 8 T gt OUT4 ET PERIOD A MUTE MUTE OUT TRIGGER 4 13V 15V 13V aa 15V 5 O COMMON pg 3 amp 6 fy A o Cito e 7 GROUND SIGNAL LEAKAGE R Fig NL820A 2 NL820A SYSTEM DIAGRAM Digitimer Ltd Page 2 of 5 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL820A Mute Facility When used with NL822 and NL824 AC signal pre amplifiers large artefact signals present at the inputs which would lead to blocking of the system can be reduced or removed by the use of a mute control In order to provide operation of this mute control without bridging the isolation barrier a logic trigger signal applied to the front panel
117. ls you simply need to use multiples of the modules illustrated above A single NeuroLog System can handle a 12 channel version of the system shown here Application Note 4 Digitimer Neurolog NeuroLog System SYSTEM A Regular Burst of Pulses with Control of Burst Duration Repetition and Output Frequency Width Overview The following scheme provides a simple means of generating a repeating burst of pulses which can be used to trigger other NeuroLog modules or TTL compatible devices such as electrical stimulators This set of modules allows control over the duration and frequency of the burst as well as the duration and frequency of the individual output pulses GENERATOR is used to em pomo PULSEGEN eae set the repetition of the PERIOD 100u8 15 som Tons 100ms burst while the NL405 WIDTH DELAY module determines the duration of the burst Note that older Width modules such as the NL401 DIGITAL WIDTH and NL403 DELAY WIDTH can be used in place of the NL405 gt Arwen XS Finally the NL301 PULSE LAYED 3 Output Pulse GENERATOR sets the i A ir Width 150us output pulse frequency 7 and width 50 150 or 500 us If these pulse widths are too limiting it Burst Repetition Burst Duration Frequency in is quite possible to add a 1s x5 5s shown 100ms x16 Burst 5 x10 further NL405 following the ia ai a snan NL301 to provide greater flexibility Figure 1 Note The rear connections ju
118. lue of 0 1uF 100nF would give an oscillation frequency of around one sixth the standard value that is 25kHz a 40us cycle Output Pulse Widths The duration width of the LOWER GATE and UPPER pulses is set by the timing components fitted to three monostables If the factory set values are not consistent with your needs these may be changed The position of these on the circuit board is shown in Fig NL201 3 Function Capacitor Value Resistor Value Standard Width LOWER C26 0 01uF R39 27k 200us GATE C25 1000pF R38 20k 15us UPPER C20 0 01uF R33 33k 230us The one point that must be considered is the fact that the GATE output when set to the Timed mode uses the LOWER pulse width to determine the existence of a signal that lies within the GATE voltage window The calculation of the Resistor and Capacitor to be used come from the following approximate equation Width 0 7 x Capacitor Resistor Note that the values used in the equation are in Farads and ohms and the circuit has the limitation on values given below Component Minimum value Maximum value Capacitor 1000pF 10uF Resistor for Lower 2k ohms 100k ohms and Upper Resistor for Gate 1500 ohms 40k ohms Example Using the factory UPPER pulse width UPPER 0 7 x 0 01E 6 x 33E3 231E 6 or 231us Digitimer Ltd Page 4 of 6 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users M
119. mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL301 NL301 Pulse Generator Introduction The NL301 PULSE GENERATOR is a low cost module for producing trains of uniform TTL pulses It can be operated continuously switched off or a single pulse can be triggered manually It is the successor to the NL3OO PULSE GEN NL301 A GATE input socket is provided to allow synchronous trains of pulses to be gated on by an externally applied TTL high logic level An internal jumper either excludes as with the NL300 or produces an output pulse coincident with the start of the GATE signal Pulse frequency is continuously variable over more than three decades using a single 12 1 control and a three position decade switch Three fixed output pulse widths are available The frequency range and pulse widths were chosen to make this module suitable as a timing source for electrical stimulation of the nervous system without the necessity of additional modules for determining the pulse width The NL301 is also useful for a variety of other timing purposes where a widely variable rate is desirable and precision is important but not critical Frequency Range The front panel control is marked in integer marks between 1 and 12 and is calibrated to be within 1 accuracy at the 1 and 10 marks At the other marks it will be within 5 accurate Even though the scale
120. mer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL405 Rear Connection IN OUT jumpers on board NL405 COMPONENT VIEW O o OO O JMP1 Parked IN Parked OUT DELAYED Fig NL405 3 On board IN OUT jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of external front panel leads This module has a choice of three output signals that can be connected to the rear connector for automatic routing to the module on the immediate right The Input signal can be disconnected from the output of the module on the immediate left if it is inappropriate The position of these jumpers are changed by gently pulling them away from the PCB then rotating them 90 180 or 270 before replacing them in two of the small gold board sockets In the Parked or N C position the jumper is placed in only one gold socket and a parking hole INPUT the upper jumper allows the Output signal from the module to the immediate left to be connected to the input socket IN or it may be parked for no connection N C OUTPUT the lower jumper selects which of the three Output signals is passed to the Input of the module to the immediate right or it may be parked for no connection N C Digitimer Ltd Page 4 of 5 Copyright 2003 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Us
121. mpers of ALL modules Repetition of Bursts should be parked as ef described in the manual A i i Actually both connections a es ee ee could be rear connection Duration of Bursts but ensure that the OUT is selected on the NL405 403 401 rear output jumper Figure 2 Application Note 7 Digitimer Neurolog NeuroLog System SYSTEM A Versatile Stimulus Timing Protocol Set Number of Trains Set Number of Bursts in a Train and Set Number of Pulses in a Burst Overview At first glance this application look quite complicated however it is essentially three separate pulse generating units providing the outputs at A B and C linked together to provide an extremely versatile system for pulse protocols The sequence is initiated by switching the upper Pulses within a Burst Pulse Frequency START TRAIN amp Pulse Width Switch to RESET then RUN to start protocol as COUNTER COUNTER PERIOD GEN COUNTER PERIOD GEN COUNTER PULSE GEN WIDTH DELAY NL304 a m IMISS 3 wg 4 5 a x w oO m 2 gt lt ot Number of Trains amp Train Interval Bursts Within a Train amp Burst Interval Fig ure 1 toggle switch on the second NL603 COUNTER to RESET and then onto RUN This pair of counters determine the number of trains passed here set at 180 but with a maximum of 9999 while the NL304 PERIOD GENERATOR gives the interval between trains he
122. nction Gate 2 Inputs 2 Input OR gate or 2 Input AND gate Selection l by on board switch Optionally 3rd Input from Gate 1 Selection l by on board switch Outputs Positive Logic OUT and Complementary Logic OUT Function selection NL501 COMPONENT VIEW JMP1 l i om Switch NOT used e Switch NOT used fT GATE 1 is OR GATE 1 is AND GATE 2 is SEPERATE GATE 1 is fed into 3rd from GATE1 1p co I P of GATE 2 GATE 2 is OR m D gt GATE 2 is AND NB Switch 2 is shown in the lt lt GATE 1 is AND gt gt position Fig NL501 2 Function Selection Switches Digitimer Ltd Page 2 of 3 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL501 Rear Connection IN OUT jumpers on board Parked IN Rear Connection is to GATE 1 I P 1 NL501 COMPONENT VIEW Gate 1 OUT Gate 1 OUT Gate 2 OUT Gate 2 OUT Fig NL501 3 On board IN OUT jumpers The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of external front panel leads This module has a choice of four output signals that can be connected to the rear connector for automatic routing to the module on the immediate right The Input signal can be disconnected from the output of the module on the immediate left if it is inappropriate The position of these jumpers are changed by genily pulling them away from the P
123. ne of two signals under logic control for recording or monitoring distribution of a logic signal to one of two stimulators as in bipolar stimulation using two stimulators see page 2 Multiplexing two analogue signals onto one oscilloscope channel a very useful secondary function etc etc etc NOTE The analogue switch is robust but has a current limit especially when the NeuroLog power supply is off Only signals originating from within the same NL900 should be coupled to the NL506 Specifications Analogue Switch Range 15V Impedance per socket 1 Mohm ON resistance lt 35 ohm Off leakage lt 50 nano Amp Switching time lt 200 nano second Break before make delay lt 10 nano second Indicator A green LED indicates the switch position Switches The SET RESET toggle switch forces the selection of the analogue switch It also presets the Flip Flop In the mid position the IN FF toggle switch selects the control signal for the analogue switch The IN FF toggle switch selects either the logic input socket or the output of the Flip Flop for the mid position of the SET RESET switch Flip Flop Is preset by the SET RESET toggle switch and toggled by the negative ve going edge of a logic input signal IN socket Allowed signal 15V max Logic threshold 1 4V approx suits TTL Impedance 10kohm approx Internal jumpers IN can be coupled to the OUT of a previous module removing the need for a
124. nel control on the NL412 provides control for output pulse durations over the range of 1 to 10 ms Setting this control allows different durations of trains of pulses when the NL412 is combined with a Pulse Generator such as the NL301 i if 4 LN pagine uud Use with NL102G When used with a NL102G that incorporates external Buzz control circuitry the duration of the Buzz is set by the front panel control See below Technical Note NL102G use During intracellular micro electrode recording cell penetration is often facilitated by use of a Buzz button a feature included on the front panel of the NL102G DC pre amplifier Pressing the Buzz button fully activates the capacitance compensation circuitry causing the amplifier voltage to oscillate This oscillation often aids passage of the electrode into the intracellular millieu In certain situations it may be necessary to operate the Buzz button in combination with microelectrode manipulation making the front panel location of the Buzz button less convenient for the user To make the Buzz feature more accessible a remote NL412 Pulse box has been developed by Digitimer Ltd This small handheld unit provides control over Buzz duration 1 10ms and has a single push button for Buzz pulse delivery The NL412 is connected via its own 2m long Lemo cable to a modified version of the NL102G incorporating an external Buzz control input socket Existing users of NL102G modules can have
125. ng to use your NeuroLog System we would urge you to thoroughly read the sections of the users manual which are relevant to your modules as well as the general section entitled NeuroLog System Basics This will introduce you to the operation of the module retention system internal communication methods and other important aspects of the equipment Mains Connection The power lead should be connected to a suitable plug The power lead is colour coded in line with international standards and must be connected as follows Insulation Colour Function Green Yellow Earth Brown Live Line Hot Blue Neutral The Earth connection MUST be made Before the power unit is plugged into the mains check that the voltage selector on the back of the case is set for the correct mains voltage The appropriate voltage should be opposite the arrow If incorrectly set use a coin of appropriate size to rotate the centre of the voltage selector to align the arrow head with the correct voltage setting Supply range Fuse Value and speed 100 120 V ac T2AL 200 240 V ac TIAL Changing the mains voltage will also require you to change the two fuses in the mains inlet They must be 5 x 20 mm in size and the value and speed shown here Grounding The Earth or Ground connection in the mains lead is continuous with the ground points on all module connectors and with the case No provision is made for opening the connection between the case ground
126. ns We reserve the right to alter specifications and price without prior notification First Issued 1984 Last Revision March 18 2005 Printed March 18 2005 File Reference N Docs Company Manuals NeuroLog NL125 NL126 lwp Digitimer Ltd Page 2 of 2 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL134 135 136 NL134 135 136 Filters 4 channel FILTER NL135 Low Pass Hz 300 500 200 100 ae 50 30 20 ae Introduction The NL134 5 6 FILTERS are 4 channel second order two pole low pass with mains frequency Notch reject NL135 6 only filter modules They are ideal partners for the NL820 Isolated Amplifier system with its 2 4 channel AC NL822 824 or DC NL832 834 pre amplifiers and the NL530 4 channel Conditioner module The filter settings have been selected for most Electrophysiological and Clinical protocols but other frequencies can be factory set to order The design is implemented using low noise active linear circuitry and does not suffer any of the aliasing problems that are encountered when cheaper methods are used A rotary switch selects the 14 frequency settings giving repeatability over a wide range with 12dB octave 40dB decade attenuation above the selected frequency value The WB wide band switch position by passes the filter sections completely both LP and Notch The active
127. nt If operated in an alternate condition it will also facilitate clearing of a blocked fluid filled electrode should this become necessary during the experiment Specification Input resistance Voltage gain Input Voltage Range to output saturation Absolute maximum input voltage range Gate leakage current Input capacity neutralization range Risetime zero source resistance 20Mohms source resistance Polarization current range Maximum noise level 10kHz bandwidth referred to input zero source resistance 10Mohms source resistance Zero Stability referred to input DC level offset range referred to input Output impedance Output voltage range Electrode impedance check 150Hz square wave Bridge balance range Calibrator External stimulus input range Depending on internal jumper setting First Issued before 1990 Last Revision January 12 2011 10 tohms X1 x10 fixed ETY 12V adjustable to zero 0 to 30pF Tusec 15usec O to 100nA 50nA 20nA 10nA SuV pk pk 1uV RMS 180V pk pk 36V RMS 100uV day 2V 600ohms 11 0V 1mV Mohms at In O to 100Mohms 0 to 200Mohms 0 to 500Mohms 0 to 1000Mohms 10mV 100uV 150Hz square wave 10V corresponds to 100nA 50nA 20nA 10nA Printed January 12 2011 File Reference N Docs Company Manuals NeuroLog NL102G odt Digitimer Ltd E mail sales digitimer com Page 4 of 4 Tel 44 0 1707 328347 Fax
128. nt panel Lemo socket Abs Max Input 100V Input Impedance 20k ohms Gain Off x0 1 x0 2 x0 5 x1 x2 x5 x10 Variable Gain x1 cal to x2 5 nom Offset control 1V or 5V Offset range 1V or 5V Filters 100Hz 1kHz 10kHz none Bandwidth DC 100kHz Crosstalk less than 56dB between channels Output Front Panel Lemo socket Output range 11V minimum Output impedance lt 5 ohms for up to 10mA load Output Input Gain ADC Variable Offsets Specifications common to all channels Clip limits Positive 4V to 11V min Negative 11V min to OV ADC Offset Zero 0 volts or 2 5V screwdriver adjustable single turn front panel preset on board controls Digitimer Ltd Page 1 of 2 Copyright 1996 8 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL530 Board Presets Switches and Jumpers The figure below shows the Presets Switches and Jumpers that alter the parameters of independent channels or all channels Gain Control OFF x0 1 x0 2 x0 5 x1 x2 x5 Shown x10 Front Panel High Offset Range Frequency OC 1V Shown Cut off SC 5V 100Hz Shown D WAO1LD N ADC Control SC to add 2 5V Negative Clip p
129. nterconnection Internal Interconnection Fig NL Basics 2 shows the input jumper arrangement for a typical module In A the jumper is being placed so that the input of this module will be connected to the OUTPUT of the module in the adjacent bay at its left In B the jumper is being placed in the no connection or NC position so that its input is NOT connected to the output of the module at the left In C the location of the jumper on a module is indicated The printed circuit board at the back of the module bay in the case contains edge connectors which supply power to each module These connectors also link the inputs and outputs of adjacent modules via conductor tracks on the printed circuit board This arrangement reduces the number of external cable connections required e g many simple system configurations only require cable connections to the preparation and monitoring instruments Internal interconnection can only be made between adjacent modules internal interconnections cannot be made for example between the output of the first module and the input of a module in the 5th bay Some inputs and outputs have not been brought back to the module edge connector because these would not normally be connected to other modules e g the output of the NL120 Audio Amp is intended to drive a loudspeaker the NL104A AC Pre amp input is normally connected either to the NL100AK Headstage or directly to a biological preparation etc
130. o NOT use rear connection NL106 Component View of PCB Rear Connections The rear edge connector in the NL900 rack allows adjacent modules to connected together without the need of front panel leads Output Signal This module has the output signal permanently connected to the rear connector for automatic routing to the module on the immediate right Input Signals The output signal from the module to the immediate left can be routed to either the IN or IN inputs or left open This is done by removing jumper in the upper rear corner of the PCB and placing it in the appropriate pair of holes We reserve the right to alter specifications and price without prior notification First Issued before 1984 Last Revision March 14 2001 Printed March 14 2001 File Reference N DOCS COMPANY MANUALS NEUROLOG NL106 SAM Digitimer Ltd Page 2 of 2 Copyright 2001 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL108A NL108A Pressure Amplifier PRESSURE AMP NL108 CALIB 1 0V OFF 100mV 1 0V 100mmHg 100mV 1cmH O OUT GND Introduction The NL108A Pressure Amplifier module provides two gain settings one appropriate for blood pressure measurement 1 0V at the output corresponds to 100mmHg pressure at the transducer and the other for low pressure measurement such as intra tracheal pressure 100mV at the output equals 1cm
131. o the monitor been replaced with the Critiflex clip pull tab manufacturer s instructions Critiflex offers new convenience in fluid filing and see N debubbling and versatility in fast flushing using the NOTE Its recommended that the three way stopcock squeeze clip or pull tab Although either the clip or WC IS integral 10 ie transducer Be located at i heart level and used exclusively for zeroing the pull tab can be used for routine fast flushing the cystem The transdiicar cin be mounted onan additional feature of the pull tab is to facilitate a Jan 7 nae hee adie HA square wave response test to aid in assessing axis The transducer can De quickly and easily vente to atmospheric pressure by turning the stopcock nami SIM pe ounance el oe eee handle counterclockwise and removing the non ST MILE Nonpyrogenic in unopened undamaged vented cap from the unused port see below p Je 2 Turn handles on the pressure line and admit Line to patient s pressure to the transducer Check quality of Patient waveform Transducer Non Vented eraing Port Cap Stopcock l Pressure Monitoring t an Sensor Line to Cet ER Patient Fluid Fastftush erann Actuators Integral 3 Way Stopcock Clip or Puil Tab Use for Zeroing Figure 8 Flush Device Overpressure Safety Valve CAUTION lf a damped waveform is observed it may be the eek result of several factors including but not exclusi
132. of 255 2550 or 25500 which is selectable by the front panel scale switch The counter will continue to increment on input pulses until the unit is reset This can be done manually with the on off reset switch or by applying a pulse to the reset socket Alternatively with the unit set to internal reset when the counter reaches full scale the unit will automatically reset There is one other reset function the external reset latch function On a reset pulse the Output will be held at the previous count level until the next reset pulse In effect the counter is reset but the output is held at its value at the time of the pulse The NL601 has two outputs The first is a simple pulse out when the counter reaches full scale count the output goes high until the counters are reset The second is the analogue output Adjustable between 1V and 11V for full scale count using the front panel output adjuster potentiometer the output will increase by 1 255 for a full scale count of 255 for every input pulse and will stay at maximum voltage for every pulse after 255 until the unit is reset TTL pulses 0 5 microseconds minimum 0 5 microseconds minimum 1 10 or 100 255 2550 or 25500 counts full scale TTL Adjustable between 1V and 11V for full scale via front panel preset 255 Last Revision July 21 2000 Printed July 21 2000 File Reference NADOCS COMPANY MANUALS NEUROLOG NL601 SAM Digitimer Ltd E mail sales digit
133. og modules plus up to 2 NL750 Averagers A unique feature of the NeuroLog power supply is a built in monitoring circuit which indicates by extinguishing the power supply indicator on the front panel excessive loading of one or more of the three supply outputs While it is expected that a power supply failure will never occur using NeuroLog modules the fault indication is invaluable when testing custom circuits built in the NL50 Blank Module The NL9OO is the heart of the NeuroLog system being the rack to house the modules as well as providing the power for them to function It also has a unique interconnection system that allows adjacent modules in most cases to pass signals between each other without the need for external cables The NL90OOD is the latest in a long line of NL900 s The design changes over the years have been due to obsolescence of parts or specification changes BUT all modules ever made will fit and work in all racks produced Unpacking Your NL900D Your NeuroLog System was delivered in a carton which was carefully designed to protect the NL900D case against damage in shipment It would be advisable to keep your carton in case you need to relocate or return your NeuroLog System some time in the future Digitimer Ltd Page 1 of 3 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NL900D Before You Start Before starti
134. on An internal jumper exists that can enable an output pulse coincident with the positive edge of the GATE signal The alternative is for the first output pulse to be one period of the selected frequency after the start of the GATE signal as was the case with the NL300 see Fig 301 1 The on board jumper LK3 is fitted to join the two pins or not Pins joined No pulse coincident with the start of GATE Pins not joined First pulse will be coincident with the start of GATE Specifications Frequency Total range lt 1 to 1200 Hz Control Single turn 270 control marked 1 12 Hz with intermediary integer panel marks Maximum range gt 0 5 12 Accuracy 1 at 1 and 12 marks 5 at other scale marks Multiplier x1 x10 x100 Internal Jumper LK2 x0 1 multiplier giving lt 0 1 to 120Hz on the front panel controls Gate Control TTL high or socket open circuit enable oscillator TTL low inhibits oscillator Internal Jumper LK3 Pins Joined No pulse coincident with GATE start Pins Open First pulse coincident with GATE start Input TTL compatible 1 TTL load maximum 15V Output pulse widths 50 150 or 500 us 45 Output fan out 10 TTL inputs Fig NL301 1 GATE OUTPUT relationships GATE in p NOTE Pulse coincident with GATE OUTPUT ewe SILL with LK3 fitted NOTE Output pulse not shortened by end of GATE a Fig NL301 1 GATE OUTPUT relationships Digitimer Ltd Page 2 of 3 Copyri
135. opyright 2000 2006 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL106 NL106 AC DC Amplifier AC DC AMP NL106 Introduction The NL106 AC DC differential Amplifier features continually adjustable amplification and DC offset with output level indication ea Ge an O gt 1V The amplification or attenuation is adjusted using a calibrated locking ten turn control where the range is set by a switch which gives the two gain ranges of 0 and x10 or 0 and x100 The input controls are similar to those of conventional oscilloscope vertical amplifiers allowing operation in AC or DC coupled single ended inverting or non inverting or differential modes Up to 2V DC at either input can be zeroed using the ten turn DC OFFSET adjustment The output voltage is shown by 4 light emitting diodes two red LED s show outputs in excess of 50mV and 1V and two green LED s show corresponding negative outputs Thus adjustment of gain and DC offset can be accomplished without an oscilloscope monitor Low drift low noise and moderate input impedance make the NL106 suitable either as an amplifier for low impedance sources or as a variable gain stage following a preamplifier Each input of the amplifier is accessible through a single pole socket and separate control of AC or DC operation with the option of amplifier grounding to remove the signal is
136. oring the voltage across a resistor fitted as a dummy load to a pair of NL800 s connected in reverse parallel as shown in the figure on the previous page The presets should be set for the best linearity of the output waveform at around the zero volt level using the correct preset for the required phase Once set for a specific NL800 that unit should be left connected or readjustment may be necessary for best linearity around zero output of the NL8OO Correct by adjusting POS PHASE control Input signal and what Output should be Correct oy J indicating area expanded to right adjusting NEG PHASE control Enlarged sections around 0 V showing cross over distortion Digitimer Ltd Page 3 of 4 Copyright 1999 2002 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL512 lt gt IN Fit jumper to use rear connection for IN analogue OJO gt S GATE Fit jumper to use rear connection for GATE in digital N C Fit jumper between these two sockets to NOT use rear connection 1V dese DAN PHASE 2 5V gt TE 10V A Shown set for a 10V FS input NEG PHASE NL512 Component View of PCB Rear Connections The rear edge connector in the NL900 rack allows the output of the module to the immediate left to be connected to the input of this module without the need of a front panel lead This is enab
137. ors and avoid the possibility of injecting micro amp currents into the preparation during the supply settling period Digitimer Ltd Page 1 of 3 Copyright 2009 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL104A HZ WB 10004 1 6G 700 3 Oe ye eM a pi Hife ST le SIH ZF H i p M U Ca L a C a a l A eld i wt ee Hh iD A a ir i E EA HH h H 3 ae TT E S ve 2 1 ee a i j AnH j clit lt a O Fig NL104A 1 View of Module s circuit board with the on board jumpers indicated On board jumpers The photograph above shows the two on board jumpers circled HF CUT this is shown in the upper circle The jumper is pulled away from the board removing it from the on board gold sockets To select the HF CUT required aligned the jumper with the centre pin and one of the other sockets as indicted below Centre and upper sockets WB no effective HF CUT modules specification of 40kKHz applies Centre and right hand sockets 6kHz HI CUT filter Centre and lower sockets 700HZz HI CUT filter Centre and left hand sockets 100Hz HI CUT filter SE OFFSET this is shown in the lower oval and allows the NL104A to be used with a NL100AK for Single Ended SE recordings As each output of a NL100AK has a DC offset which is nulled out by the A B front panel switch position this has to be
138. preparation grounding to optimise recordings Switches allow selection of 1 of 3 calibrated output levels with 1 of 2 calibrated triggered pulse widths of either polarity The calibration level at the preset amplitude and polarity may also be enabled or pulsed manually from a front panel switch 2V on the positive edge with a 200mV hysteresis 15V maximum gt 1Mohm 0 1mV 1mV 10mV switch selectable 2 1 or 10msec triggered or under manual control 2 triggered positive or negative switch selectable 2 ohms 20 ohms 200 ohms for output levels of 0 1 1 10mV respectively 50V First Issued October 30 2007 Last Revision January 12 2011 Printed January 12 2011 File Reference N Docs Company Manuals NeuroLog NL410 oat Digitimer Ltd Page 1 of 1 Copyright 2010 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL412 NL412 Pulse Introduction The NL412 PULSE is a small handheld general purpose pulse generator which can be used to start experiments command the gate of a train of pulses or be used with an NL102G to Buzz electrodes The NL412 is self powered by a standard internal 9 V battery and is fitted with a 2m lead terminating in the standard Lemo connector Start On pressing the button the NL412 generates an active high pulse which will trigger remote modules Gating The front pa
139. r NL100AKS headstages the bridge excitation voltage should be set to Position 9 15V Digitimer Ltd Page 1 of 2 Copyright 2010 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL109 Half Bridge Full Bridge Mode An onboard jumper hi lighted by the yellow circle in the photograph below sets the NL109 to Half Bridge or Full Bridge Full Bridge mode is used for standard differential inputs while the Half Bridge mode allows single ended non differential input signals to be amplified and filtered via the INPUT In this mode the INPUT is set at the centre point between the and Bridge Excitation values Specification Summary Input voltage range gt 1 5V Working 15V Absolute Gain x1 to x5 000 1 2 5 sequence Cal Calibration Calibration control provides 0 to 40 gain reduction High Frequency Cut 0 3 to 30 000HZ 1 3 10 sequence 10 Low Frequency Cut DC 0 1Hz or 10Hz 20 Zero Button Presses longer than 1s in duration activate the zero circuit the light sequence below is followed For offsets of 300mV RTI the zero function will move the baseline to within 5uV of zero For larger offsets of up to 8V RTI the baseline is brought within 50uV of zero Zero Bi colour LED Constant Green Normal working state autozero successful Off Performing Autozero Zero pressed for longer than 1s
140. re set at 10s The third counter determines the number of bursts within each train 10 while the A Trains m interval between bursts is set ore by the second NL304 200ms aa en Finally the number of pulses within a burst 4 is set on the last counter pulse frequency 100Hz is set on the NL301 PULSE GENERATOR and pulse width 200us is controlled by the settings on the NL405 WIDTH DELAY B Bursts C Single Burst of Pulses Figure 2 Application Note 12 Digitimer NeuroLog NeuroLog System SYSTEM Simple Biphasic Pulse Generation of a Defined Duration Burst Overview Here a trigger pulse is used to initiate a burst of biphasic constant current stimulation from a pair of NL800 STIMULUS ISOLATORS The burst duration and total stimulus duration are controlled by a pair of NL405 WIDTH DELAY modules however the same role could be fulfilled by the older NL401 DIGITAL WIDTH module As with all NeuroLog applications there is plenty of scope for the users to customize the arrangement to better suit their requirements WIDTH DELAY PULSE GEN WIDTH DELAY O 0 a X lt oO a D O Cc J g Ke sj I m gt x m iw m E gt Z m iw The burst can either be triggered by an external device which produces a TTL compatible output such as our NL412 PULSE box another NL301 PULSE GENERATOR as used to control the pulse frequency or the NL304 PERIOD GENERATO
141. s Output Plugs Input Plug Input Leads NeuroLog System NL800A 10V at 30mA nominal for full scale output Standard 1 pole NeuroLog Lemo socket 0 to 10mA in 4 overlapping decade ranges 1mm gold sockets lt 5us 1kohm load lt 20us typical tungsten microelectrode load lt 40us 1Mohms resistor load gt 900Mohms lt 1pF 3 of full scale output for each output range 120 x 65 x 40 mm 4 7 x 2 6 x 1 6 excl knob and removable feet 220g including batteries Batteries are fitted 2 x 1mm gold plugs with heatshrink sleeving for insulation Digitimer Part Number NL800A BATT NL970 10 1mm Gold stacking plugs 10 pieces NL962 Standard NeuroLog Lemo Plug NL951 xx Double ended Lemo plug lead where xx 15 30 45 cm or 1m 2m NL951B xx Double ended lead with Lemo plug at one end and BNC at other where xx 1m or 2m NL952 Single ended lead with Lemo plug on one end Tinned wires at other end Length is 2m We reserve the right to alter specifications and price without prior notification First Issued February 2007 Last Revision February 23 2007 Printed March 1 2007 File Reference N Docs Company Manuals NeuroLog NL800A v01 lwp Digitimer Ltd E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Page 8 of 8 Copyright 2007 Website www digitimer com Users Manual NeuroLog System NL820A NL820A Isolator 4 channel ISOLATOR NL820 Introduction
142. s also provided so that the direct signal can be viewed SPECIFICATION Input Max signal that can be processed without distortion is 1 Volt Input overload The input is protected up to 75V Time constants 20 50 100 200 500 and 1000 msec accuracy better than 4 Integrate Direct Either the integrated signal or the input signal is selectable by this switch If direct is selected the integrator is reset to zero Output The output produces a signal which has a gain of unity from the input but integrated with respect to time at the time constant selected Output impedance 6000hms in integrate Connected to input socket in direct Digitimer Ltd Page 1 of 1 Copyright c 1990 Users Manual NeuroLog System NL800A NL800A Stimulus Isolator Introduction The NL800A STIMULUS ISOLATOR is a battery powered opto coupled isolator It has a constant current output with very high output impedance making it suitable for stimulation through microelectrodes as well as with gross electrodes Normally driven from the NL510A PULSE BUFFER its output current is set by the 10 turn AMPLITUDE control on the NL510A within the output range set by the switch on the NL800A output pulses have the same timing as the input pulses 2 microseconds to 30 seconds output pulse width Features of the NL800A are its very small physical size for mounting close to the preparation low battery consumption excellent isolation lt 1pF output to
143. s not loading the pulse generator by examining the pulse amplitude at the TTL input R may require adjustment accordingly Some pulse sources may not be able to supply sufficient current to achieve the 2 4V high logic level into 3300hm Logic inputs should not have negative voltages or positive voltages greater than 5 5V applied to them Although the input circuits may not necessarily be damaged by exceeding these limits every effort should be made not to connect analogue outputs to logic inputs e g the NL104A AC Pre amp output which can vary between 13V should not be connected to the NL603 Counter input Similarly TTL outputs are intended to drive TTL inputs either those of NeuroLog logic modules or inputs of other equipment which accept standard TTL signals The logic modules should not be used to drive high capacity loads e g connecting a logic output to a remote piece of equipment through a long piece of screened cable is a high capacity load or used to drive apparatus not specifically designed for TTL levels e g the NL301 Pulse Generator should not be connected directly to a preparation for voltage stimulation or be used to drive relays etc Any NeuroLog TTL output will in general drive any 10 NeuroLog TTL inputs in parallel Digitimer Ltd Page 2 of 6 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NeuroLog System Basics Module I
144. s will reduce interference from external sources and match offset components inherent to the low noise high input impedance stage in the NL100AK Single ended recordings can be accomplished by grounding the B input of the NL100AK with the input cable having the U shaped 1mm jumper supplied the U shaped plug is pushed into the B and GND inputs and the flying lead is used to provide the ONLY ground connection for the preparation See catalogue application note entitled Avoiding Ground Loops In this way any common mode interference picked up at both the A and B inputs of the NL100AK can be summed out by the NL104A A DC path must be provided from each input of the NL100AK to the system ground This DC path may of course be through a high resistance microelectrode It is also essential for the best noise performance to make the ground connection to the biological preparation through the GND terminal of the NL100AK If the NL100AK is used differentially with both A and B inputs connected through electrodes to the preparation a connection to the NL100AK GND should still be made to the preparation Differential Recordings Although the NL100AK Headstage is most frequently used with high resistance microelectrodes its very low noise allows it to be used with low resistance electrodes eg for differential recordings of action potential through gross electrodes WARNING It should be pointed out that if the input device of or
145. se will be 5mV SUV x1000 with 10kHz BW When the NL104A is used to make differential recordings input switch in the A B position the BALANCE control is adjusted to minimise common mode signals such as mains interference or shock artefacts present in the recording The adjustment will differ from one situation to another depending on the relative magnitudes of the interference signals at the two inputs and on differences in input electrode resistance etc The internal common mode oscillator makes it possible to quickly return the NL104A to a balance after such adjustments Specification Summary Gain 100 200 500 1K 2K 5K 10K or 20K Input resistance 10Mohms High frequency cut off 100 700 6K or WB gt 40k Hz selectable Low frequency cut off 0 1Hz or 10Hz Common mode rejection ratio 10 000 1 at 50Hz 80dB Input noise lt 10uV pk to pk with input grounded and bandwidth 0 1Hz to 10kKHz Dynamic balance adjustment gain for one input can be varied 25 with respect to the other Output voltage range 12V max CAUTION When using the NL104A AC Pre Amplifier either with or without the NL100AK headstage do not switch the NL900 POWER switch on or off while the biological preparation is connected to the inputs Switch the power on before these connections are made and disconnect the preparation before the power is switched off during an experiment This routine will reduce the risk of damage to the FET input transist
146. system and the mains earth lead Power Unit Protection The power unit supplies three stabilised voltages 5V 15V and 15V each of which is completely protected against excessive load with its own internal current fold over circuit which can sustain an indefinitely long short circuit Each of the supplies is also protected by fuses fitted to the rear panel which protect the power transformer against a gradually applied overload A suddenly applied overload may not blow a fuse before the fold over protection circuit acts Fuse Ref Supply Protected Fuse Value and speed F3 5V T4AL F4 amp F5 15V T 1 25A L The indicator light on the case front panel is illuminated when all three power supplies in the power unit are operating with correct output voltages If the indicator does not light when the mains power is switched on POWER switch on the front panel either one of the supplies is faulty or an overload condition exists A module malfunction or faulty circuits constructed on the NL50 Blank Modules may be the source of the excessive power unit load Identify and remove the overload if the indicator is still unlit check the fuses Digitimer Ltd Page 2 of 3 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL900D Rack Mounting Brackets A pair of rack mounting brackets are supplied as standard with each NL900D These need only b
147. t High Pass is an ideal partner for the NL820A Isolated Amplifier system with its 2 4 channel AC NL822 824 or DC NL832 834 pre amplifiers and the NL530 4 channel Conditioner module In combination with either the NL135 136 or NL134 Filters a full 4 channel low frequency and high frequency cut off system is provided The filter settings have been selected for most Electrophysiological and Clinical protocols but other frequencies can be factory set to order The design is implemented using low noise active linear circuitry and does not suffer any of the aliasing problems that are encountered when cheaper methods are used A rotary switch selects the 14 frequency settings giving repeatability over a wide range with 12dB octave 40dB decade attenuation below the selected frequency value The DC switch position by passes the filter sections completely Go 2 Specification Summary Input voltage range 15V max gt 10V operating Input impedance 120kQ2 Filter settings 6dB 0 1 0 2 0 3 0 5 1 2 3 5 10 20 30 50 100 200 Hz and DC Cut off accuracy 3 0 01HzZ lt 6 3Hz 3 0 63HZ gt 6 3Hz Gain after cut off 1 0 Attn below cut off 40dB decade 12dB octave Crosstalk better than 60dB Noise lt 100uV rms Output DC offset lt 10mV Output voltage range 10V Output impedance lt 60092 Rear connections to the motherboard allow Input and Output interconnections between this and newer NL820A NL13
148. tage input signal will produce an isolated bipolar current output through the load preparation Controlling 3 channels from 1 DAC and 3 digital lines NL512 NL800 NL512 NL800 NL512 NL800 NL800 NL800 NL800 Enable Channel 3 Enable Channel 2 es Enable Channel 1 Analogue signal With this arrangement you can control multiple bipolar channels one at a time from a PC card with a single analogue output and multiple digital control lines being used to enable the required channel Digitimer Ltd Page 2 of 4 Copyright 1999 2002 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL512 Each NL800 is factory set for a 10 V input giving the selected Full Scale current output but they will each have different DC Offsets The NL512 needs to be adjusted to match the NL800 s used Input Signal Signal to Positive Phase NL800 Signal to Negative Phase NL800 This diagram shows a bipolar input signal and the signals to the two NL800 s The solid areas indicate where each NL800 operates Note that the DC offset of each NL800 is automatically added to the input signal before being applied to the NL80O0O Setting the Output DC Offset linearity for NL800 s refer to diagram of controls on next page This is adjusted independently for each NL800 and performed by applying a bipolar ramp or sine wave signal to the input of the NL512 and monit
149. ter each fast flush fo ensure return to desired drip rate of 2 to 4 ccs hour micro drip rate of 2 to 4 drops per minute Potential Complications Sensis Intection Positive cultures can result from contamination of the pressure system Increased risks of septicemia and bacteremia have been associated with blood sampling infusion fluids and catheter related thrombosis Air Emboli Air can enter the system and ultimately the patient through stopcocks that are inadvertently left open from accidental disconnection of the pressure system or from flushing residual air bubbles into the patient Clotted Catheter and Bleed Back lf a flushed system is not adequately pressurized relative to the patient s own blood pressure bleed back as well as clotted catheter may occur Overinfuston Excessive flow rates may result from pressure greater than 300 mmHg This may result in a potentially harmful increase in blood pressure and or fluid overload Abnormal Pressure Readings Pressure readings can change quickly and dramatically because of loss of proper calibration loose connections or air in the system WARNING ABNORMAL PRESSURE READINGS SHOULD CORRELATE WITH PATIENT S CLINICAL MANIFESTATIONS IF NOT VERIFY THE TRANSDUCER FUNCTION WITH A KNOWN AMOUNT OF PRESSURE BEFORE INSTITUTION OF THERAPY XLT Guin anseaid z0 Wang ZHEF Um X10 mgm amseasd jo wang ZHSFI 3 Wiad X10 AGUeN DOs WEUOSAY l afue
150. the rear panel Model Case style 5V Power Supply NL900 Original design with a pale blue top cover retained by four screws 5A and regulated by transistors NL900A Same case as above Regulated by 5A regulators NL900B Same case as above Regulated by 3A regulators NL900C Second design of case The top cover was a light grey colour with Regulated by 3A regulators pale blue insert strips Access from the top is NOT possible The rack mounting brackets fold flat to the side plates when not required NL900D_ Third design of case The top cover is royal blue with four retaining Regulated by 3A regulators screws This case has removable rack mounting brackets We reserve the right to alter specifications and price without prior notification First Issued May 15 2002 Last Revision September 27 2005 Printed October 13 2005 File Reference N Docs Company Manuals NeuroLog NL900D iss02 lwp Digitimer Ltd Page 3 of 3 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NL905 NL905 Compact Case and Power Unit The NL905 Compact Case and Power Unit is an enclosed case which will accept up to 4 single width NeuroLog System modules This case is designed as a more compact counterpart to the full width NL900D which can hold up to 13 modules and as a result it can be conveniently transported and placed on the laboratory bench T
151. the modification made at Digitimer Ltd Specifications over Digitimer Ltd Page 1 of 2 Copyright 1999 2000 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual Specification Summary Button LED Pulse Duration Range Accuracy Output Level Rise and Fall times Battery Power consumption Cable Size Weight NeuroLog System NL412 Only produces an output pulse on Press not release Amber illuminates for approximately 250 ms after each press 1 to 10 ms better than 20 at all scale markings 9 V with new battery lt 100uUs Standard 9 V 6LR61 style Non alkaline supplied We recommend the Duracell Ultra MN1604 alkaline battery lt 5 UA static 2m nom with standard Lemo connector fitted 61 x 105 x 28mm w xh xd plus 15 mm on d for knob lt 170 g including battery We reserve the right to alter specifications and price without prior notification First Issued 1999 Last Revision December 12 2000 Printed December 12 2000 File Reference N DOCS COMPANY MANUALS NEUROLOG NL412 SAM Digitimer Ltd E mail sales digitimer com Page 2 of 2 Tel 44 0 1707 328347 Fax 373153 Copyright 1999 2000 Website www digitimer com Users Manual NeuroLog System NL501 NL501 Logic Gates LOGIC GATES NL501 Introduction The NL501 LOGIC GATES module contains two logic gates each with two inputs and B 1 complementar
152. tially reduced 1 5m 5ft of miniature 4 conductor screened cable will have approximately 150pF capacitance between each conductor and the screen If connection is made through 1Mohm electrodes frequency response will begin to fall off above 10kHz For lower resistance electrodes the frequency response is of course affected to a lesser extent We reserve the right to alter specifications and price without prior notification First Issued before July 1984 Last Revision May 12 2009 Printed May 12 2009 File Reference N Docs Company Manuals NeuroLog NL104A 03 lwp Digitimer Ltd Page 3 of 3 Copyright 2009 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL104F NL104F Very Steep FILTER addition for NL104A Introduction Baa The NL104F FILTER is a very steep low pass filter for removal of A C PREAMP medium frequency interference signals It has to be fitted to a MES NL104A AC PRE AMP Sh GAIN TK ges ar It has been found to be very successful when used to record 500 20k neurone activity extracellularly whilst eye position was monitored 900 using a 50KHz magnetic field system 100 NON INVERT The module is assembled to a NL104A either at the factory or can be added by a user This requires a screwdriver and one solder joint INVERT BAIFA 0 7 he The Filter provides a flat response to higher than 18kHz with attenuation of gt
153. tral position See Fig NL Basics 2 If the output of one module is connected internally back connected to the input of the module in the next bay to the right two front panel sockets become available for additional parallel connection Each of these the output socket of the left module and the input socket of the right module are connected together internally External cable connections can be made to these either for joining the output to more than one input in parallel e g the output of the NL304 Period Generator might be connected to the inputs of 2 or more NL403 Delay Width modules or for making connection to monitoring equipment such as oscilloscopes or recorders Digitimer Ltd Page 3 of 6 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 873153 Website www digitimer com Users Manual NeuroLog System NeuroLog System Basics IMPORTANT Some caution is necessary with this back connection system due to the ease with which two outputs can be connected together at a single input If the input drive for one module is supplied through a cable connection to the input socket on the front panel and the module bay to the left has a module in it the possibility exists that two outputs one through the cable the other via a back connection will be joined This can be avoided by putting the input jumper of the module receiving the external input drive in its NC no connection position Permanent damage is unlikely to
154. ual is not currently available for that module Please contact Digitimer for assistance For obsolete modules which are not included in this manual please contact us and we can send you a copy of the relevant section First Issued 1972 Last Revision January 30 2013 Printed January 30 2013 File Reference N Docs Company Manuals NeuroLog Contents lwp Digitimer Ltd Page 2 of 2 Copyright 2013 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NeuroLog System Basics NeuroLog System Basics Module Lock and Module Insertion All NeuroLog System cases are fitted with a sliding bar for retaining the modules This retaining lock is operated by the knob at the top of the case front panel A module is inserted into its guides until its front panel is within about 10mm of the front of the case The locking knob is pushed sideways to the right towards the UNLOCK position about 5MM The module can then be pushed the rest of the way into the case and the locking knob returned to the LOCK position If each module is not pushed firmly home the movement of the locking slide will be impeded Do not use excessive force in pushing the locking knob against its mechanical stops Do not try to force the modules into or out of the case without operating the lock IMPORTANT Do not put heavy objects on top of the NeuroLog case since this will bend the case frame making
155. ut Gain and Impedance checking of each amplifier electrode The front panel inputs use the new 1 5mm DIN safety connectors as required by the latest specifications in the BS EN 60601 IEC601 BS5724 series Section 2 25 ECG machines amp Section 2 26 EEG machines This unit is particularly suited for use where there are very large stimulus artefacts for example when used close to a magnetic stimulator coil In these cases the stimulus artefact would normally swamp the pre amplifier inputs resulting in a tail with a long time constant that obliterates the response The special circuitry of the NL844 eliminates this as long as good recording practice is followed see page 2 The input circuit automatically adjusts to the DC input conditions and a non linear filter subsequently modifies its time constant if the differential input signal exceeds its normal 20mV working range Therefore fast short artefacts do not block the subsequent stages This results in an amplifier with a very fast recovery time from stimulus artefact pulses Each channel has a connector for the non inverting input that is often called the Reference on EEG machines and inverting input that is often called the Active on EEG machines As the amplifier is differential both must be used on active channels The COM connector must always be connected to the patient to provide a reference potential for the amplifiers A deblock button provides the user
156. ve A Solution IV Roller to Administration Ciamp Mis positioned stopcocks Set a ey Air in the monitoring fine and or catheter or gt cannula Loose fine connections Electrical Improperly calibrated monitor Connector Blood clots in the catheter cannula or pressure monitoring line Figure 2 Ohmeda DTX Ptus Transducer with integral Flush Device iti aid Attached IV Administration Set rr or cannula positioned against a vessel WARNING STOPCOCKS MUST BE POSITIONED 90 FOR OFF POSITION DO NOT POSITION STOPCOCKS AT 45 TO ACHIEVE AN OFF POSITION FORTY FIVE DEGREE POSITIONING OF STOPCOCKS I IMPRECISE AND MAY RESULT IN PATIENT CONTAMINATION BLEED BACK OR AIR EMBOLISM WARNING THE FLUSH DEVICE iS NOT INTENDED TO BE USED AS A PRECISE FLUID DELIVERY MECH ANISM IF DUE TO THE PATIENT S CONDITION PRECISE FLUID DELIVERY IS NECESSARY A PUMP SHOULD BE UTILIZED TO PREVENT POSSIBLE OVERINFUSION 3 Allow approximately one minute for the system to equilibrate and then make a drip count to ensure that the flush cevice is operating properly a flow of 2 to 4 microdrops per minute A visual inspection for leaks should also be made Thirty minutes after installation and periodically afterwards the system should be checked for proper infusion bag pressure flow rate and leaks Any small leaks can give misrepresentation of actual flow rate through the catheter Also observe drip rate af
157. y The NL254 is recommended for users who wish to monitor the frequency of a particular event such as neuronal spiking respiratory or heart rate or even the frequency of pulses generated by our own pulse generating modules such as the NL301 or NL304 Setting the Trigger Threshold Pressing the middle SET TRIGGER THRESHOLD button changes the 3 digit display from the measured rate to the trigger threshold voltage which can then be adjusted between 0 00V and 4 00V using the LEVEL CONTROL dial Once the SET TRIGGER THRESHOLD has been adjusted to the desired level the user can press any of the three limit threshold buttons or wait 3 seconds for the display to revert to the rate display The Trigger Threshold voltage is the same in all 4 rate modes PPS LO PPS PPM and LO PPM and will persist when the Neurolog System is powered off Setting the Upper amp Lower Rate Limits As with the SET TRIGGER THRESHOLD button the LOWER lt and UPPER gt limits can be set by first pressing the appropriate limit button and then adjusting the LEVEL CONTROL dial to the desired rate limit Once the UPPER or LOWER LIMIT has been adjusted to the desired level the user must press any of the three limit threshold buttons or wait 3 seconds for the display to revert to the rate display before the new setting will take effect Unlike the Trigger Threshold voltage the UPPER and LOWER limits set are specific to each mode PPS LO PPS PPM and LO PPM and will p
158. y are replaced Now Test and set up the unit Digitimer Ltd Page 4 of 5 Copyright 2000 2006 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL104F Fitting the NL104F to a current NL104A Step 1 Solder the supplied 1mm socket to the leg of the lower of three resistors as shown Ensure that the joint is secure and is not touching either of the other two resistors NB Cable shown where IC would be at this stage Step 2 Remove the IC and connect the ribbon cable as shown Also plug the 1mm pin shown on White Red wire into the 1mm socket fitted above Ensure that the HF filter jumper is in the required position as later movement is tricky Step 3 Fit the NL104F to the NL104A using the screws provided On the NL104F ensure that there are two plain washers between the PCB and the panel lug Between the plastic spacer and NL104A ensure that there is a plain washer at one end top and solder lug onto the front panel PCB at the other end lower If the NL104A had two plain washers between the PCB and panel lug ensure that they are replaced Now Test and set up the unit We reserve the right to alter specifications and price without prior notification First Issued February 4 2000 Last Revision August 16 2006 Printed July 16 2009 File Reference N Docs Company Manuals NeuroLog NL104F v5 lwp Digitimer Ltd Page 5 of 5 C
159. y outputs GATE 1 Both of these gates can be independently configured by PCB mounted switches as either 2 inout AND gates or 2 input OR gates The open circuited inputs are automatically held low for the OR function or high for the AND function so that external connection need not be made A further switch allows expansion of the second gate to take the output of the first as a third input This enables a 4 input AND gate or a 4 input OR gate to be realised A further possibility is a 3 input AND or OR gate where one of those inputs is a 2 input OR or AND function from the other gate Possibilities 2 x 2 Input OR gates 2 x 2 Input AND gates 1 x 2 Input OR gate plus 1 x 2 Input AND gate 1 x 4 Input OR gate 1 x 4 Input AND gate 1 x 4 Input mixed mode gate 1 x 2 Input OR gate or 1 x 2 Input AND gate with the output as the 3rd input to 1 x 3 Input OR gate or 1 x 3 Input AND gate Q INPUTS z9 are GATE 2 E z o l M EXPAND O INDEPENDENT Fig NL501 1 Logic Diagram of NL501 Digitimer Ltd Page 1 of 3 Copyright 2005 E mail sales digitimer com Tel 44 0 1707 328347 Fax 3873153 Website www digitimer com Users Manual NeuroLog System NL501 Specification Summary Inputs TTL 1 TTL load Outputs TTL Output will drive 10 loads Function Gate 1 Inputs 2 Input OR gate or 2 Input AND gate Selection by on board switch Outputs Positive Logic OUT and Complementary Logic OUT Fu
160. y the NL603 t 300ms DELAY to 10th pulse set by NL405 0 Outputs A amp C added by NL501 OR Gate Here the Neurolog System is producing a continuous series of trigger pulses which can pace a heart at a fixed rate set by the NL301 PULSE GENERATOR The effective refractory period ERP is often measured in cardiac research by trying to evoke a premature beat while the heart is being paced A premature beat can be inserted after a number of regular beats 10 in this example through the use of the NL603 COUNTER and an NL405 WIDTH DELAY The NL603 can also be configured to insert this extra stimulus once or repeatedly after a user specified number of beats The NL405 allows the user to vary the delay introduced between the last regular beat and the premature beat By bringing the outputs of the NL405 and the NL301 together at the NL501 LOGIC GATE and setting it to OR the two inputs the triggers from these two modules are combined meaning that a stimulator connected to the output of the NL501 here our own DS3 Isolated Constant Current Stimulator receives both the delayed and non delayed TTL trigger pulses itimer Neurolog Application Note 22 Digitimer NeuroLog System ng Using the NeuroLog System for Cardiac Pacing and Studies of Ventricular Fibrillation A m m m tas Al is 0m a m EF ata PULSE GEN COUNTER WIDTH DELAY NL301 RESET NL603 x NL405 DS3 Current Stimulators with pulse duration
161. ys a true measure of the DC potential existing at the electrode system whereas the x10 output can be set to give zero over a range of standing electrode potentials The range of this control will enable the x10 output to be set to zero over a range of 2V at the electrode input to the system Monitor Out This socket provides a voltage proportional to the current injected into the electrode system by the current injection circuitry fitted to the NL102G The calibration of this system is such that a maximum signal of 10 volts at the socket represents full scale injection current for the range selected by the jumper plug on the left hand module board The ranges provided by this selector are 10nA 20nA 50nA and 100nA but it should be noted that the MONITOR output signal will only truly measure the injection current if the electrode impedance does Digitimer Ltd Page 2 of 4 Copyright 2011 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL102G not exceed values of 1000Mohms 500Mohms 200Mohms and 100Mohms respectively Out This output connection is the x10 amplifier output As the output dynamic range is 11V the output saturates at an input signal of 1 1V In addition to this 1 1V up to 2V with respect to the input can be offset with the DC LEVEL control before the output saturates Impedance Check When the IMPED CHECK switch is put in the ON position a 1nA
162. ze 400mm x 400mm oS O m Rated Load kg 50 100 150 200 250 Proof Load 150 of Rated Load Ultimate Breaking Load 300 of Rated Load Output 2 0 mV V at Rated Load 10 Accuracy lt 0 02 of Rated Load Non Repeatability lt 0 01 of Rated Load Excitation Voltage 10vdc recommended 15vdc maximum Bridge Resistance 4150 Insulation Resistance gt 500MQO 100vdc Pa ene Range 20 to 70 C Co ge 10 to 40 C lt 0 002 of Rated Load C Span Temperature Coefficient lt 0 001 of Rated Load C Connection Type PVC screened cable 1 5m long Wiring Connections Green ve supply Black ve supply Blue vesense Brown ve sense Red ve signal White ve signal 150 Mechanical Dimensions All dimensions in milllmeters ial 38 b goff M6 mounting holes First Issued January 29 2013 Last Revision January 30 2013 Printed January 30 2013 File Reference N Docs Company Manuals NeuroLog NL63 odt Digitimer Ltd Page 1 of 1 Copyright 2013 E mail sales digitimer com Tel 44 0 1707 328347 Fax 373153 Website www digitimer com Users Manual NeuroLog System NL100AK NLIOOAK Headstage The NL100AK is supplied with several fittings and accessories 1 A 6 35mm diameter 0 25 metal mounting rod which fits into the hole at the rear of the NL100AK next to the output cable and is secured by a small grub screw This rod can be used to secure the N

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