MSDS - Traconed
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1. enrichment Although fire may not be involved the chance of accidental ignition is reduced by the use of water fog which also helps to dissipate the oxygen Materials Where low temperatures are encountered due to contact with cold gas or liquid some metals and plastics become extremely brittle and may fracture Stainless steels nickel steels and copper have good low temperature characteristics BOC will advise on appropriate materials and safeguards against low temperature embrittlement on request With liquid oxygen extreme care must be taken in the choice of jointing materials which must be compatible with oxygen Expert advice should be sought The surface finish can also be important where liquid oxygen or high pressure gaseous oxygen is concerned Advice can be obtained on materials through BOC Safety Officers Liquid oxygen transfer As any leakage of liquid oxygen onto combustible material such as carpeting wooden tiles bitumen and asphalt is potentially explosive it is strongly recommended that all transfer operations are carried out on non combustible non porous flooring such as concrete cement or paving tiles In the event of a leak where it is safe to do so the source of liquid should be isolated and the area ventilated LEGAL CATEGORY General sales list PACKAGE QUANTITIES Liquid cylinder data Nominal Nominal Nominal Continuous Approx Approx liquid gas operating flow weight cylinder capacity capacity pressure r2. A risk of hypothermia arises when liquefied gases are released All persons at risk should be warmly clad Hypothermia is possible in any environment below 10 C but susceptibility depends on length of exposure atmospheric temperature and not least the individual older people are more likely to be affected Symptoms The symptoms of hypothermia are i A slowing down of physical and mental responses ii Unreasonable behaviour or irritability iii Speech or vision difficulty iv Stumbling Treatment If possible take the person s temperature The mouth temperature should be over 96 F 35 C Persons apparently suffering from hypothermia should be wrapped in blankets and moved to a warm place Seek immediate medical attention No direct form of heating should be applied except under medical supervision Protective clothing Liquid oxygen is extremely cold To prevent injury from unprotected parts of skin coming in contact with cold parts of the equipment it is recommended that non absorbent leather gloves and goggles or protective glasses are worn during filling operations If clothing becomes contaminated with liquefied gas or vapour the wearer should ventilate it for a minimum of 5 minutes walking around in a well ventilated area High reactivity The following points apply to oxygen and oxygen enriched air Oxygen is an active element which although non flammable supports combustion of almost all materials As a resul
3. exercise the oxygen content may fall to 3 4ml In very active tissue almost complete extraction occurs PRODUCT LICENCE NUMBER PLO735 0009 DATE OF PREPARATION June 1994 Revision 1 M BOC Medical Customer Service Centre Priestley Road Worsley Manchester M28 2UT Tel 0800 I 11 333 Fax 0800 I 11 555 www boc com bocmedical uk gases boc com BOC Medical is a trading name used by operating companies within The BOC Group the parent company of which is The BOC Group PLC The stripe symbol and the word BOC are registered BOC Group trademarks Copyright The BOC Group PLC 2002 Safe handling and storage of medical liquid oxygen cylinders The following practices are recommended for the safe storage handling and use of medical liquid oxygen cylinders General Only trained persons should handle liquid cylinders 2 Observe all regulations and local requirements regarding the storage of liquid cylinders 3 Do not remove or deface labels provided by BOC for the identification or the contents 4 Ascertain the identity of the gas before using it 5 Know and understand the properties and hazards associated with each gas before using it 6 Before using liquid cylinders establish plans to cover any emergency situations that might arise 7 When doubt exists as to the correct handling procedure contact BOC 8 If you own your liquid cylinder you must be aware of and discharge your statutory obligation
4. Careful monitoring is required but modern methods of measuring oxygen in breath blood and tissues have made this relatively simple Almost invariably oxygen is administered through the lungs by inhalation The major exception is when a metered supply is fed into the oxygenator of the extracorporeal circulation of a cardio pulmonary by pass system CONTRA INDICATIONS WARNINGS ETC There are no absolute contra indications to the use of oxygen but the inspired concentration should be limited in the case of premature infants and those patients with chronic bronchitis and emphysema Interactions with other medicaments and other forms of interaction The pharmacokinetic activity of oxygen is modified by changes in the blood carbon dioxide tension but this has little clinical significance Effects on ability to drive and to use machines In normal circumstances oxygen does not interfere with the conscious level but patients who require continuous oxygen support will require individual assessment as to their ability to drive or to operate machinery Other undesirable effects frequency and seriousness Oxygen toxicity can occur as manifested by W retrolental fibroplasia in premature infants exposed to oxygen concentrations greater than 40 W central nervous system toxicity including dizziness convulsions and loss of consciousness after only 2 3 hours of exposure to pure oxygen at 2 or more atmospheres e g sports and deep sea diving re
5. M j 7 BOC Medical Data Sheet Medical Liquid Oxygen O23 Liquid cylinder supply PRESENTATION Pharmaceutical form Compressed medical gas for medicinal use only Specification Complies with European Pharmacopoeia specifications 1985 Purity gas phase 99 5 min Carbon dioxide 300 0vpm max Carbon monoxide 5 0vpm max Physical data Molecular weight 32 00 Physical state in cylinder Liquid Specific volume at 15 C and 1013mb 738 2 W kg Boiling Point at 1013mb 183 C Density of gas at 15 C and 1013mb 1 355 kg m Density of liquid at boiling point 1 14 g ml Critical temperature 118 4 C Specific gravity of gas at 15 C and 1013mb_ 1 106 Gaseous oxygen is colourless odourless tasteless non toxic non irritant and non flammable but supports combustion vigorously Liquid oxygen is pale blue boiling at 183 C at atmospheric pressure In the gaseous state of 15 C and 101 3mbar its volume increases approximately 840 times USES Modern anaesthetic practice is almost totally dependent on oxygen which provides a dimension of safety that makes possible some of the complicated medical manoeuvres required by modern surgery and without which the risks would be too great to justify the method Of equal value is the use of oxygen in intensive care units where it provides the main life saving support particularly for patients whose lungs need to be artificially ventilated if they are to survive Although the
6. ate empty dimensions litres litres bar min kg mm 148000 150 300 1588 x 508 dia 787 x 356 dia 318x 185 dia NOTES 1 Actual liquid volume may vary during storage 2 Actual flow rates may vary depending upon the number of liquid cylinders in use 3 This is the approximate weight of the liquid cylinder and control equipment without gas 4 This is the approximate weight of the empty liquid cylinder and control equipment together with the nominal capacity of liquid 5 BOC Walkabout service only FURTHER INFORMATION Expiry date Three years from filling date Pharmacological particulars The characteristics of oxygen are Odourless colourless gas Molecular weight 32 00 B Boiling point 183 1 C at bar E Density 1 355kg m at 15 C Oxygen is present in the atmosphere at 21 and is an absolute necessity for life The basal oxygen consumption in man is about 250ml min for a body surface of 8sq metres It is reduced by about 10 during anaesthesia and natural sleep and by about 50 for a 10 C fall in body temperature Alveolar air contains about 14 oxygen at 14 kpa 105mm Hg and the arterial blood has an oxygen tension of 13 kpa 97mm Hg The difference known as the alveolar arterial oxygen tension gradient increases with age The difference may be as great as 4 kpa 30mm Hg in a healthy elderly individual Oxygen in the blood is mostly combined with haem
7. e stored and operated in a vertical position 3 Never lay store or move a liquid cylinder on its side Check for gas leaks using approved leak detection solution 5 Before connecting the liquid cylinder for use ensure that back feed from the system into the cylinder is prevented 6 Before connecting liquid cylinders check the complete gas system for suitability particularly for pressure rating and materials 7 Never permit liquefied gas to become trapped in parts of any system as this may result in rupture of the system 8 Ascertain that all electrical systems in the area are suitable for service with each gas 9 Never use direct heat or electrical heating devices to raise the pressure of a liquid cylinder 10 Never re compress a gas from a liquid cylinder without consulting the supplier I1 Never attempt to transfer gases from one liquid cylinder to another except where they are specifically designed for this operation 12 Do not attempt to increase draw off rate by adjusting the pressure setting without first checking with the supplier 13 Do not use the liquid cylinder for any other purpose than to contain the gas as supplied 14 Never permit oil grease or other readily combustible substances to come into contact with valves 15 Keep valve outlets clean and free from contaminants particularly oil and water 16 Do not subject liquid cylinders to abnormal mechanical shocks which may cause damage to their valve
8. immediate management of cardiac arrest does not depend on an oxygen supply other than that in the ambient air continued treatment almost invariably depends on artificial ventilation with supplementary oxygen The use of oxygen in chronic respiratory and cardiac conditions is very often essential and it is needed for the relief of all forms of hypoxia other than histotoxic In short modern medicine could not be practised without the support that oxygen provides Oxygen is widely used Bj in clinical practice to provide a basis for virtually all modern anaesthetic techniques as well as pre and post operative management Mto restore the tissue oxygen tension towards normal by improving oxygen availability in a wide range of conditions such as cyanosis of recent origin as a result of cardio pulmonary disease surgical trauma chest wounds and rib fractures shock severe haemorrhage and coronary occlusion carbon monoxide poisoning hyperpyrexia major trauma eg road traffic accidents and gunshot wounds W in the management of sudden cardiac and respiratory arrest whether drug induced or traumatic W in the resuscitation of the critically ill when the circulation is impaired Bj in neo natal resuscitation DOSAGE AND ADMINISTRATION There is no distinction generally between the use of oxygen in age groups other than neonates see below The fundamental indication is the presence of hypoxia due to whatever cau
9. ional exposure standard OES There is no OES for medical liquid oxygen in the UK Health hazard information Hazards to health arise from intense cold or displacement of air by rapidly evaporating liquid Effect of cold on lungs Transient exposure to very cold gas can provoke an attack of asthma in susceptible subjects Prolonged breathing of extremely cold gas may damage lung tissue Cold burns and frostbite Because of the low temperature of liquefied gases below 183 C the liquid or even cold vapour or gas can produce damage to the skin Unprotected parts of the skin coming in contact with uninsulated items of cold equipment may also stick fast to them and the flesh may be torn on removal Symptoms Local pain usually gives warning of freezing but sometimes no pain is felt or is short lived Frozen tissues are painless and appear waxy with a pale yellowish colour Thawing of the frozen tissue can cause intense pain Shock may occur if the area is large Immediate treatment Loosen any clothing that may restrict blood circulation and seek immediate hospital attention for all but the most superficial injuries Do not apply direct heat to the affected parts but if possible place the affected part in lukewarm water Sterile dry dressings should be used to protect damaged tissues from infection or further injury but they should not be allowed to restrict the blood circulation Alcohol and cigarettes should not be given Hypothermia
10. ly a sterile dressing Obtain medical assistance Ingestion is not considered a potential route of exposure Supports combustion Exposure to fire may cause containers to rupture explode Non flammable None All known extinguishants can be used If possible stop flow of product Cool with water from a protected position None Evacuate area Ensure adequate ventilation Eliminate ignition sources Use protective clothing Try to stop release Prevent from entering sewers basements and workpits or any place where its accumulation can be dangerous Ventilate area Keep area evacuated and free from ignition sources until any spilled liquid has evaporated Ground free from frost Use no oil or grease Segregate from flammable gases and other flammable materials Suck back of water into the container must be prevented Do not allow backfeed into the container Use only properly specified equipment which is suitable for this product its supply pressure and temperature Contact your gas supplier if in doubt Keep ignition sources including static discharges away from vessel Refer to supplier s operating instructions Do not smoke while handling product Ensure adequate ventilation Protect eyes face and skin from liquid splashes Avoid oxygen rich gt 21 atmospheres 32 219 C 183 C 118 C I 1 air 1 1 1 water 1 Not applicable 39mg 1 Bluish liquid No odour warning proper
11. n Components Impurities CAS Nr EEC Nr from EINESC Hazards identification Hazards identification First aid measures Inhalation Skin eye contact Ingestion Fire fighting measures Specific hazards Hazardous combustion products Suitable extinguishing media Specific methods Special protective equipment for fire fighters Accidental release measures Personal precautions Environmental precautions Clean up methods Handling and storage Handling and storage Exposure controls personal protection Personal protection Physical and chemical properties Molecular weight Melting point Boiling point Critical temperature Relative density gas Relative density liquid Vapour pressure 20 C Solubility mg water Appearance Colour Odour Autoignition temperature Flammability range Other data 097B Oxygen refrigerated 02 0645 645555 0800 I 11 333 Substance Contains no other components or impurities which will influence the classification of the product 07782 44 7 2319569 Refrigerated liquefied gas Contact with product may cause cold burns or frostbite Oxidant Strongly supports combustion May react violently with combustible materials Continuous inhalation of concentrations higher than 75 may cause nausea dizziness respiratory difficulty and convulsion Immediately flush eyes thoroughly with water for at least 15 minutes In case of frostbite spray with water for at least 15 minutes App
12. oglobin Normally haemoglobin in arterial blood is 97 saturated and the oxygen content of the blood in 19 8 vol 0 3ml of this being carried in solution The remainder is held in chemical combination with haemoglobin The concept of oxygen availability can be expressed as the product of the cardiac output and the oxygen content of the blood The average healthy individual with a basal oxygen consumption has no more than 4 minutes supply of oxygen in the blood Pharmacokinetic particulars The uptake of oxygen by the blood in the lungs and discharge to the tissues is determined by the oxygen dissociation curve The characteristic sigmoid shape ensures that at tensions between 5kpa 40mm Hg and 2kpa 15mm Hg the oxygen carried in the blood from the lungs can be readily given up to the tissues Oxyhaemoglobin Dissociation Curve here Empr Ameir Yr oa PF F 5 fuom Carnes Aiiaip a I i b H 5 m i Hi r ami A fi as i f f ermer E ou a aka Ao The uptake from the lungs is rapid because blood flow through the capillaries where exchange takes place occurs in about 0 5 seconds The uptake of oxygen is favoured by the simultaneous loss of carbon dioxide which is then excreted in the expired air Conversely the entry of carbon dioxide into the blood from the tissues facilitates oxygen transfer to the cells At rest mixed venous blood returning to the lungs contains 13 l4ml of oxygen per 100ml but with severe
13. parated from the driver s compartment Ensure vehicle driver is aware of the potential hazards of the load and knows what to do in the event of an accident or an emergency Before transporting product containers ensure that they are firmly secured and adequate ventilation compliance with applicable regulations 008 001 00 8 O R81C R34 O Oxidising 8 34 2I Road transport symbols are used and selected according to the most stringent product classification EC or ADR Label 2 non flammable non toxic gas Label 05 fire intensifying risk R8A Strongly supports combustion RFb May cause frostbite SI7A Keep away from combustible material use no oil or grease S9 Keep container in well ventilated place S36A Use suitable protective equipment Before using this product in any new process or experiment a thorough material compatibility and safety study should be carried out Details given in this document are believed to be correct at the time of going to press Whilst proper care has been taken in the preparation of this document no liability for injury or damage resulting from its use can be accepted MED 004043 APUK 1206 5C
14. s safety devices or the vessel itself 17 Never attempt to repair or modify valves or safety relief devices ANY DAMAGE to valves should be reported to BOC 18 Close the outlet valve and pressure building valve whenever gas is not required even if the liquid cylinder is still connected to the equipment 19 Liquid cylinders should be positioned in such a way that discharge from safety devices does not impinge on other cylinders or apparatus or into areas used by personnel Further information concerning specific problems arising from the storage and handling of gases hazards and first aid treatment can be obtained from BOC General references Handbook of Compressed Gases Compressed Gas Association Inc Reinhold 1990 Patty F A Editor Industrial Hygiene and Toxicology 3rd edition Vol 2 John Wiley amp Sons 1981 Gas Data Book Matheson Gas Products 1971 British Compressed Gas Association CP 9 Code of Practice The Safe Filling Handling Storage and Distribution of Gases in Transportable Containers 1982 Safe Under Pressure BOC Limited Gas Encylopedia L Air Liquide Elsevier 1976 Care with Cryogenics BOC Limited Liquid Cylinder User Manual BOC Limited SAFETY DA EET I Identification of the substance preparation and of the company 6 MSDS Nr Product name Chemical formula Company identification Emergency telephone Composition information on ingredients Substance Preparatio
15. s with regard to maintenance and testing 9 Ensure that any driver that collects a liquid cylinder from a supplier has been properly instructed in the method of handling liquid cylinders and in dealing with any emergency Storage Liquid cylinder storage compounds should be purpose built and well ventilated 2 Liquid cylinders should be used and stored in locations free from fire risk and away from sources of heat and ignition 3 The liquid cylinder storage compound should be kept clear and access restricted to authorised persons only The compound should be clearly marked as a liquid cylinder store and appropriate hazard warning signs displayed e g oxidant liquid gas etc 4 Smoking and the use of naked flames either inside or in the vicinity of the liquid cylinder storage area should be prohibited 5 Liquid cylinders should be stored in the vertical position and properly secured to prevent toppling 6 Liquid cylinders stored in the open should be protected against extremes of weather 7 Full and empty liquid cylinders should be stored separately and full liquid cylinders arranged so that the oldest stock is used first 8 Liquid cylinders held in storage should be periodically checked for general condition and leakage Handling and use Only use appropriate trolleys roller bases or overhead hoists correctly attached for transporting liquid cylinders even for a short distance 2 Liquid cylinders should always b
16. se Modern oxygen usage requires separate devices for administering the gas in high and in low concentrations The lowest concentration should not fall below that present in ambient air 20 9 These devices have been classified as follows Fixed Performance Systems patient independent high flow venti masks low flow anaesthetic circuits In all these systems the oxygen concentration is pre determined by the clinician Variable Performance Systems patient dependent without re breathing catheters and cannulae with re breathing through a face mask such as the MC Edinburgh and Pneumask These systems only function by means of the patient who creates the inspired mixture by the act of breathing Various patient and device factors influence the result Special care is needed when oxygen is administered to neonates where the inspired concentration should not exceed 40 because of the risk of retrolental fibroplasia to elderly chronic bronchitic patients in whom the inspired concentration should only be raised in stages of 1 and probably should not exceed 30 in hyperbaric chambers in the management of conditions such as carbon monoxide poisoning anaerobic infections and acute ischaemic disease Convulsions and other central nervous system CNS effects may occur at 2 atmospheres or more after a few hours exposure to pure oxygen At higher pressures more rapid onset of CNS symptions will occur
17. t materials which are normally only combustible at elevated temperatures in air will burn violently in oxygen with the smallest source of ignition see section on materials 2 Oiland grease should never be used on equipment for oxygen service Pipes fittings and controls in contact with oxygen must be degreased 3 No fuel paint solvent or other volatile flammable material may be stored within 3m 10ft of a liquid oxygen cylinder 4 Oxygen must never be used as a substitute for compressed air or nitrogen 5 Impregnation of clothing by oxygen must be prevented as a minute spark will ignite oxygen impregnated cloth causing serious burns 6 With good ventilation at ambient temperatures oxygen will disperse quickly However cold gas for example from a liquid leak or leakage into badly ventilated chambers will seep into porous materials soil fissures drains and ducts Ignition sources should then be avoided Before entering or working in such spaces the atmosphere should be checked by suitable gas detection equipment Fire It is not usually possible to extinguish an oxygen fed fire using conventional means The first essential step in extinguishing such a fire is to eliminate the source of supply of the oxygen Conventional methods may then be employed as necessary Usually a white mist forms by the condensation of atmospheric moisture when liquid oxygen is in contact with it and this indicates the approximate extent of the area of oxygen
18. ties Not applicable Oxidiser Gas vapour heavier than air May accumulate in confined spaces particularly at or below ground level 10 Stability and reactivity Stability and reactivity I 1 Toxicological information General 12 Ecological information General 13 Disposal considerations General 14 Transport information UN Nr Class Div Subsidiary risk ADRIRID Item Nr ADR RID Hazard Nr Tremcard Nr Labelling ADR Other transport information 15 Regulatory information Number in Annex of Dir 67 548 EC Classification Symbols R Phrases S Phrases Labelling Symbols Risk phrases Safety phrases 16 Other information Ensure all national local regulations are observed Ensure operators understand the hazard of oxygen enrichment May react violently with combustible materials May react violently with reducing agents Violently oxidises organic material Liquid spillages can cause embrittlement of structural materials Risk of explosion if spilt on organic structional materials eg wood or asphalt See page 3 Can cause frost damage to vegetation To atmosphere in a well ventilated place Do not discharge into any place where its accumulation could be dangerous Contact supplier if guidance is required 1073 2 2 5 1 2 7a 225 119 Label 05 fire intensifying risk Label 2 non flammable non toxic gas Avoid transport on vehicles where the load space is not se
19. trosternal soreness associated with coughing and breathing difficulties made worse by smoking and exposure to cold air after breathing pure oxygen at atmospheric pressure for several hours Use in pregnancy and lactation Oxygen does not adversely affect pregnancy and lactation Other special warnings and precautions Oxygen supports combustion and smoking should be prohibited when oxygen is in use and no naked flame should be allowed Care is needed in the handling and use of medical oxygen gas cylinders Overdose symptoms emergency procedures antidotes As detailed in Other undesirable effects Incompatibilities major There are no incompatibilities with oxygen in clinical practice PHARMACEUTICAL PRECAUTIONS Cylinders should be kept out of the reach of children Oxygen is non flammable but strongly supports combustion including some materials which do not normally burn in air It is highly dangerous when in contact with oils greases tarry substances and many plastics due to the risk of spontaneous combustion with high pressure gases The normal precautions required in the storage and use of medical gas cylinders are applicable These are fully explained in the associated brochure Gas Safe in the hospital and on the reverse of this Data Sheet United Nations Substance Identification UNSI No 1073 Emergency action code Hazchem 2PE A D R Hazard identification No 225 C E F I C tremcard No 119 Occupat
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