User Manual - Starr Life Sciences
Contents
1. 000503 HypoxyDial STARR Life Sciences values its customers and is dedicated to providing quality products and solutions to meet your needs If you have any questions or you need ANY replacement parts please call or email STARR Life Sciences at 1 866 978 2779 ext 5 or technicalsupport starrlifesciences com 8 Intellectual Property Protecting the HypoxyDial 2005 2011 STARR Life Sciences Corp All rights reserved STARR Life Sciences the STARR Life Sciences logo and other STARR Life Sciences marks are owned by STARR Life Sciences and may be registered P N 100537 Rev 2 0 HypoxyDial STAR RAN KL USER MANUAL LIFE SCIENCES CORE STARR Life Sciences the STARR Life Sciences logo and other STARR Life Sciences marks are owned by STARR Life Sciences Corporation and may not be used without express written permission of STARR Life Sciences Corporation Technology Warning US and foreign patents are pending Unauthorized reproduction or distribution of this HypoxyDial system or certain portions of it will result in civil and criminal penalties and will be prosecuted to the fullest extent possible under the law 9 Warranties and Liabilities Limited Warranty amp Disclaimer STARR Life Sciences SLS warrants its non disposable hardware and sensors the Non disposable Products against defects in material workmanship and performance for a period of one 1 year from the date of shipment SLS2. ARR HypoxyDial HypoxyDial Patents Pending User Manual STARR Life Sciences Corp 333 Allegheny Avenue Suite 300 Oakmont PA 15139 STARR Life Sciences Corp 2011 P N 100537 Rev 2 0 STAR RAN KL USER MANUAL LIFE SCIENCES CORE Table of Contents 1 INTRODUCTION AND GENERAL SYSTEM LA YOU TP o0000000000000000000000 000000 0000000000000000 0000000000000000 1 2 HYPOXYDIAL PACKAGED PARTS esososooooo0o0000e0000000000000000 00000000000000 0000000 0000000000000000 nenen 00000 1 3 SYSTEM REQUIREMENTS AND DETAILED DESCRIPTION 6600000000000000000000000000000 0000000 000000000000 1 3 1 BASIC HYPOXYDIAL SYSTEM SPECIFICATIONS csccccecescscscsceecscescscescsceccecscescesescscesescesescesescesecs 1 32 YPOXYDIAL M REGULATOR EE 2 3 3 YPOXY DIAL GAS BLENDER EN 2 3 4 HYPOXYDIAL FLOW METER c cccececceccececcececescscecscuscscccecuccscucesceceececeecscecsceseectsesctsescecescesensacs 4 3 5 HYPOXYDIAL HUMIDIFIER CHAMBER AND OUTLET Host 4 4 SETTING UP THE HYPOXYDIAL SYSTEM u ccecccccccccccccccccccccccccccccccccccccccccccccccccccees 5 5 HYPOXYDIAL APPLICA TIONS ccccccccscccccccccccccccccccccccccccccccccccccccccccscscceccccccccccccccccccccsccccccceces 9 3 1 MECHANICAL VENTILATION ASSIS NEEN 9 5 2 ISOFLURANE DELIVERY c ccscesceccecceccecccceccecceceecesceccsccsceecescecesceecscescsctsceeceecssescescescssessescesseseuscescess 10 6 WARN
3. the Warranty Period SLS warrants that the Non disposable Products will meet the electronic and mechanical specifications stated in the SLS user manual although the specifications are subject to change without notice SLS at its option will repair or replace a Non disposable Product that is found to be defective during the Warranty Period Defective Non disposable Products must be received at STARR Life Sciences Corp 333 Allegheny Ave Suite 300 Oakmont PA 15139 no more than thirteen 13 months from the original date of shipment by SLS All shipments must include a Return Authorization Number RMA obtainable from SLS and must be sent freight prepaid by the sender This warranty is nontransferable This warranty does not apply to any defects or damages caused by an animal or resulting from alteration modification neglect misuse usage of improper power sources damage in transportation abuse or any cause other than normal use of the Non disposable Products This warranty does not apply to products resold by SLS that are manufactured by other companies No warranty or claim is made by SLS regarding the efficacy of any product for any particular application Except for the Limited Warranty expressly set forth above SLS MAKES NO WARRANTIES WHATSOEVER SLS HEREBY DISCLAIMS ALL WARRANTIES EXPRESS OR IMPLIED ORAL OR WRITTEN INCLUDING WITHOUT LIMITATION ANY IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE
4. OR ANY IMPLIED WARRANTIES ARISING FROM ANY COURSE OF DEALING USAGE OR TRADE PRACTICE In no event shall SLS be liable for any damages whatsoever arising out of the use of its product including without limitation any direct incidental or consequential damages any damages for loss of profits business interruption loss of information or any pecuniary loss even if SLS has been advised of the possibility of such damages Important Notice SLS products are designed to be used while under the supervision of research scientists in an experimental application All items sold by SLS are for NON HUMAN use The user is solely responsible for determining the suitability of any items from SLS for their particular application ALL SOFTWARE MANUALS COMMUNICATIONS ETC WILL BE IN THE ENGLISH LANGUAGE ONLY M HypoxyDial P N 100537 Rev 2 0 12
5. fittings on each are of the DISS type and therefore cannot be interconnected with each other Either end of both hoses can be connected to their respective regulators Simply hand tighten the end of the hose that fits on the regulator outlet fitting It is not necessary to use a wrench 3 Attach the N Hose to the HypoxyDial Blender Lay the blender upside down on a surface and attach the other end of the nitrogen hose to the appropriate connection on the bottom of the blender In the correct orientation the nitrogen inlet will be on the right bottom side of the blender while the air inlet will be on the left bottom side Again the hoses cannot be interchanged jeighxodiy The fitting entering into the blender body is left handed so by tightening the hose fitting you may inadvertently loosen the fitting inside the blender body To prevent this you can use a wrench to maintain PIN 100537 Rev 2 0 6 HypoxyDial STARRY USER MANUAL LIFE SCIENCES CORP tightness on the body fitting while tightening the hose fitting 4 Mount the HypoxyDial Blender on the Stand Remove the tripod stand from its box and retract the legs Before mounting the blender on the stand make sure that the bracket on the top of the stand is facing one of the three legs as shown below This orientation will help to prevent the system from tipping Next place the assembled blender in the bracket Once the blender is sitting on the stand attach the ot
6. INGS CAUTIONS AND OPERATIONAL NOTES 10 7 REPLACEMENT PARTS ACCESSORIES AND TECHNICAL SUPPORT 11 8 INTELLECTUAL PROPERTY PROTECTING THE HYPONYDIALIM 20 0 ek RER ee 11 9 WARRANTIES AND LIABILITIES cccccccccsccscccccccccccccccccccccccccccccccccccccccccccccccsccccccscccccees 12 HypoxyDial P N 100537 Rev 2 0 1 STAR RAN KL USER MANUAL LIFE SCIENCES CORE 1 Introduction and General System Layout Thank you for purchasing the HypoxyDial from STARR Life Sciences The HypoxyDial is the simplest device available that will allow you to quickly and easily adjust fractional oxygen delivered to your animals We hope that you will be completely satisfied with the system A basic schematic of the HypoxyDial system is given below Air Regulator HypoxyDial Blender Air Hi Press Hose 20 ft A SA GR 4 ERN Humidifier w FU Safety Popoff N Hi Press Hose 20 ft N Regulator 2 HypoxyDial Packaged Parts The following 15 a list of parts that should be included in your HypoxyDial shipping box HypoxyDial Blender Nitrogen Pressure Regulator 50 psig preset CGA 580 inlet fitting Medical Grade Air Pressure Regulator 50 psig preset CGA 346 inlet fitting Nitrogen Supply Hose 20 ft black Air Supply Hose 20 ft yellow Flowmeter Rotameter Humidifier Chamber with Pressure Safet
7. Pressure Up to 1500 psi 10 3 MPa with gas tanks OR 50 10 psi 345 70 kPa to blender USE ONLY THE PARTS THAT COME WITH YOUR HypoxyDial SYSTEM DO NOT SUBSTITUTE ANY PARTS 3 2 HypoxyDial Regulators The pressure regulators that are provided with your HypoxyDial and that attach to the supply gas sources are preset to 50 psig DO NOT tamper with these regulators as the presetting allows your system to operate safely and accurately The regulators do not need any specific maintenance although we recommend that you use clean gas sources that do not contain rust water or other particulate matter 3 3 HypoxyDial Gas Blender The gas blender 15 the heart of the HypoxyDial Although it is a purely passive mechanical device it is important that you understand its basic operation and maintenance requirements Important details regarding these issues are provided below Gas Mixture Accuracy If there is sufficient flow through the blender see details in Outlet Delivery Ports section below the blender will be accurate to 1 To assure accuracy some other considerations are germane If better accuracy is desired we recommend that you compare the at your dial setting with that from an oxygen analyzer e Use only clean dry medical grade supply gases e Always allow sufficient time for equilibration of the gas mixture at your downstream delivery point after adjusting the The equilibration ti
8. applicable to the schematic CGA Compressed Gas Association Standard fittings for high pressure gas tanks Each gas type has its own designated number DISS Diameter Index Safety System Standard set of high pressure gas fittings designed specifically to prevent inadvertent errors in mechanical connections with medical grade gases BA Body Adaptor The male half of a DISS fitting N N Nut Nipple The female half of a DISS fitting 1 Connect the Air and Nitrogen Regulators to the Gas Tanks The HypoxyDial comes with two regulators air and nitrogen that are preset to 50 psi DO NOT ADJUST this pressure by turning any knobs on the top of the regulators The regulators are outfitted with standard Compressed Gas Association CGA fittings that will allow them to be connected to their respective tanks Each regulator should be tightened with a wrench To replace any of the gas tanks after the gas has been depleted you should close the valve on top of the tank then remove the regulator at the CGA fitting HypoxyDial P N 100537 Rev 2 0 5 STAR Rah USER MANUAL LIFE SCIENCES CORP Note that the air regulator has a cap on the inlet side To remove this simply pull the sleeve toward the regulator body and it should pop off 2 Connect the Supply Hoses to the Regulators The air and nitrogen regulators have special connecting hoses The air hose is yellow and the nitrogen hose is black and the
9. bleach solution or light detergent in water after each use with animals HypoxyDial P N 100537 Rev 2 0 10 USER MANUAL WARNING WARNING CAUTION CAUTION CAUTION OPERATIONAL NOTE LIFE SCIENCES CORP a When using low pressure tubing always use the humidifier chamber with the pressure safety popoff DO NOT connect low pressure tubing directly to the flow meter without this safety valve in place The HypoxyDial uses high pressure gas Shut all supply valves and vent gas from the lines before removing or disconnecting any parts from the HypoxyDial System DO NOT obstruct ports or vents on the bottom of the blender Condensed water in the gas supplies can cause malfunction of this device Use only clean dry medical grade gases with the HypoxyDial Always disconnect the gas sources from the blender when the blender is not in use We recommend that you use an Oxigraf Oxygen Analyzer or equivalent analyzer to verify and 7 Replacement Parts Accessories and Technical Support The following are adjunct or replacement parts for the HypoxyDial HypoxyDial Replacement Parts 100513 N Regulator 100543 Air Regulator 100527 N Connection Hose 208 Black 100542 Connection Hose 20ft Green 100517 Blender Stand 100519 Flow Meter 100535 High Pressure Outlet Hose 5ft Green 100520 Humidifier Accessory Devices 000001 MouseOx Control Box 000501 OxyDial
10. er It has a hose barb port that accommodates tubing from 1 8 to 1 4 inch In addition to allowing you to humidify the gas if you choose it more importantly has a safety feature to prevent the downstream pressure from becoming excessive The humidifier chamber is equipped with a pressure safety popoff M HypoxyDial P N 100537 Rev 2 0 4 STAR USER MANUAL LIFE SCIENCES CORP valve that allows the gas to vent if the pressure exceeds a threshold of 3 psi Thus you MUST use the humidifier chamber if the system that you are connecting to cannot accommodate the high pressure outlet hose 4 Setting Up the HypoxyDial System Instructions for setting up the HypoxyDial System are described here Please refer to this schematic for assembly of the HypoxyDial System O Flow Meter Inlet DISS N N O Outlet DISS BA O S Hi Press Hose 3 ft green i Inlet DISS N N Air Regulator 50 psi preset Inlet CGA 346 Air Hi Press Hose black HypoxyDial Blender Outlet DISS BA Air Inlet DISS N N Air Air Inlet DISS BA Air Outlet DISS N N Air Inlet DISS N Outlet DISS BA O Outlet DISS N N O N Hi Press Hose green Inlet DISS N N N Outlet DISS N N N Humidifier w 4 lt OR N Regulator 50 psi preset Safety Popoff User Su lied Inlet CGA 580 Inlet DISS N N O pp Outlet DISS BA N Outlet tube opening The following definitions are
11. her end of the air hose to the fitting on the bottom of the blender 5 Attach the Flow Meter Attach the flow meter to either of the outlet ports on the sides of the blender Be sure to choose the correct port for your application see Outlet Delivery Ports in Section 3 3 above Once attached the fitting should be tightened gently with a wrench Make sure that the flow meter is in a vertical position so that its reading will be as accurate as possible n HypoxyDial IN rN O NL SS Su A mrm HypoxyDial P N 100537 Rev 2 0 7 STAR Rah USER MANUAL LIFE SCIENCES CORP Attach the High Pressure Outlet Connection 5 ft Hose Your HypoxyDial comes equipped with 2 different outlet connections The first outlet connection is 5 foot 1 5 m section of high pressure hose that will allow you to connect the HypoxyDial directly to an isoflurane dispenser or other device equipped with an oxygen DISS body adaptor and that can handle pressures above 50 psi This particular hose is equipped with hand tight nuts so it is unnecessary to tighten them with a wrench This hose can be connected to the flow meter outlet but you can also opt to connect this high pressure hose directly to the blender without passing through the flow meter as shown in the figure below Instructions for attaching the flow meter are provided just above Note that if you choose to leave the flow meter in place and the device to w
12. hich you are connecting also has a flow meter or other user adjustable flow limiting orifice you should open the flow valve on the HypoxyDial flow meter all the way to reduce its flow restriction as much as possible 6b Attach the Low Pressure Outlet Connection Humidifier Bowl The other outlet connection is a humidifier bowl with a pressure safety popoff This humidifier is a bubble through type and it connects directly to the bottom of the flow meter It has an outlet hose barb that can accommodate tubing between 1 8 and 1 4 inch inner diameter to connect to other devices The bowl should be filled and operated with the water level between the minimum and maximum lines If you do not want to humidify you can simply use the chamber completely empty The most important feature of the humidifier however is the pressure safety popoff which vents the system when pressures inside the bowl exceed 3 psi Because of its overpressure safety utility you MUST use the humidifier bowl when connecting the HypoxyDial System to devices that are not rated for high pressure Pictures of the fully assembled system are shown below with the flow meter located on either outlet of the blender HypoxyDial P N 100537 Rev 2 0 8 STAR Rah USER MANUAL LIFE SCIENCES CORP 5 HypoxyDial Applications The HypoxyDial can be used to conduct hypoxia studies in different applications which include Provide control during
13. hown in the sketch below This system should also be used with a MouseOx pulse oximeter to allow you to monitor the health of your animals while they are under anesthesia MouseOx O Saturation Heart __Breath Rate Isoflurane al 7 Vaporizer Jh ges nose cone Isoflurane Vaporizer OxyDial setup 190 Scrubber ae high pressure hose 6 Warnings Cautions and Operational Notes WARNING Always use the HypoxyDial in an adequately ventilated area WARNING DO NOT use the HypoxyDial around open flame WARNING Place HypoxyDial on level surface when operating it WARNING When mounting the blender on the tripod stand align blender with one of the legs of the stand to provide more mechanical stability WARNING DO NOT lay tubing from the HypoxyDial in areas where it can represent a tripping hazard WARNING DO NOT lay tubing from the HypoxyDial System in areas where it can be inadvertently grabbed such that heavier parts of the system can be tipped or pulled from surfaces WARNING If the stand with mounted blender seems like it might tip extend the legs of the stand further to increase mechanical stability WARNING Investigational device only All parts are NOT for use on humans WARNING DO NOT substitute any parts that come with your HypoxyDial with other external parts or fittings WARNING Wipe external surfaces of the blender flow meter and hoses with 10
14. lastomeric components such as seals and O rings These materials will degrade and or wear over time commensurate with the level of usage and cleanliness of the supply gases resulting in degradation of performance reduction in accuracy These materials are designed M HypoxyDial P N 100537 Rev 2 0 3 STAR RAN KL USER MANUAL LIFE SCIENCES CORP to function for a minimum of 2 years but will eventually need to be replaced A service life of 3 years should be considered maximum even under the best conditions To have your blender serviced please contact STARR Life Sciences at 1 866 978 2779 ext 5 or technicalsupport starrlifesciences com 3 4 HypoxyDial Flow Meter The flow meter is a type of variable area meter known as a rotameter It has a tiny ball that floats via drag from the gas as it passes through the barrel The indicated flow is specified from the vertical center of the ball Because of the nature of this flow meter it 15 important that the rotameter be oriented vertically in order to allow you to read it accurately Also the rotameter is only accurate if the gas pressure at its inlet is 50 psi This particular rotameter is calibrated for oxygen so if flow measurement accuracy is desired we provide an expression to allow you to correct for the difference because the HypoxyDial can only deliver a maximum of 21 It can be shown that the actual flow is related to the flow on the rotameter barrel by the follo
15. me is dependent on the volume of tubing hose and other parts connected to the blender M HypoxyDial P N 100537 Rev 2 0 2 STAR RAN KL USER MANUAL LIFE SCIENCES CORE Inlet Supply Gas Pressure The air and nitrogen inlet supply pressures must be 50 psig in order for the flow meter to work properly The regulators that come with your HypoxyDial system are preset to 50 psig outlet pressure DO NOT tamper with these regulators Supply Gas Pressure Differential Reed Alarm The blender is equipped with a passive alarm reed alarm that will indicate when the gas supply pressures differ The alarm which has the sound of a loud whistle will activate whenever the two inlet gas pressures differ by more than 15 20 psig The alarm can sound for a number of reasons Startup If the gas supplies are not simultaneously pressurized or if only one gas supply source 15 pressurized e Shutdown If the gas supply pressures bleed down at different rates when they are turned off or if only one of the supplies was closed e Depleted Gas One of the supply gas sources is depleting causing its pressure to drop e Regulator Tampering If someone has tampered with the regulators so that they are not set at 50 psig Outlet Delivery Ports The blender has 2 outlet delivery ports labeled Outlet no bleed Accurate 3 30 LPM left side and Outlet w bleed Accurate 0 30 LPM right side Both ports deliver the same blended gas but the
16. mechanical ventilation Provide control during isoflurane anesthesia delivery Details on how to implement these HypoxyDial applications are given in the sections below 5 1 Mechanical Ventilation Assist The HypoxyDial System can be used to provide hypoxic gas combinations with user specified oxygen fraction to a mechanical ventilator A basic functional configuration is shown in the figure below The HypoxyDial should be connected to a location on the ventilator that receives its inlet gas If the ventilator cannot accommodate the high pressure outlet hose you must use tubing in conjunction with the humidifier and pressure safety popoff as shown in the figure below If the ventilator requires dry gas you can simply not fill the humidifier bowl but you still need to use the humidifier because of its overpressure safety feature Mechanical Ventilator OxyDial setup Mouse QO Saturation Heart Rate L small bore tubing Breath Rate wl Mechanical Ventilator PIN 100537 Rev 2 0 9 HypoxyDial S TA R RA ro USER MANUAL LIFE SCiENCES CORE 5 2 Isoflurane Delivery The HypoxyDial can be used to provide gas with a user specified oxygen fraction to be employed in conjunction with an isoflurane vaporizer You can simply use the 5 foot high pressure outlet hose to connect to the vaporizer from either the HypoxyDial flow meter or directly from the blender A typical setup would be similar to that s
17. wing expression F 0 875 0 125 Q actual O ia 1 0 0 where O 18 the true volume flow rate L min Q ameter 1S the volume flow rate read from rotameter barrel L min and 1 is the oxygen fraction indicated blender dial face 2 Of course you can also invert this equation to calculate the rotameter flow that you would set based on a desired actual flow We have 0 875 0 125 2 100 ices TT 3 5 HypoxyDial Humidifier Chamber and Outlet Hose The HypoxyDial System comes equipped with 2 types of outlet connections The first is a high pressure oxygen hose that connects directly from the flow meter to a device that has an O5 DISS connector and that permits pressures up to 50 psi such as an isoflurane dispenser This hose and any device that it can connect to that has the appropriate DISS fitting are rated for this pressure You must assume that other hose connections are NOT rated for this pressure and you should use caution in connecting this system using such devices The issue 15 that if flow passing through whatever is attached to the flow meter is blocked the pressure inside the attached material will reach 50 psi causing a potential safety hazard To accommodate the use of the HypoxyDial with devices not properly rated for pressure we provide a second connection option the humidifier chamber which also connects directly to the outlet of the flow met
18. y Popoff High Pressure Outlet Hose 5 ft green Tripod Stand with Blender Mount HypoxyDial User Manual Please check to see that you have all of these parts If you find any part missing please contact STARR Life Sciences at 1 866 9STARR9 ext 9 or by e mail at support starrlifesciences com 3 System Requirements and Detailed Description 3 1 Basic HypoxyDial System Specifications Product Description The HypoxyDial System is a product that allows you to quickly and easily dial any oxygen fraction Pia in Air N gt gas mixtures between 0 and 21 Using universal fittings the system connects to centralized M HypoxyDial P N 100537 Rev 2 0 1 STAR RAN KL USER MANUAL LIFE SCIENCES CORP supplies bottles or wall outlets of air and nitrogen The user simply turns a dial to set the oxygen percentage and can adjust the outlet flow rate to obtain a constant stream of gas at the desired and flow rate The system is purely mechanical and uses no electrical power All hoses and fittings to connect from the bottled gas source to the HypoxyDial system are provided Range 0 to 21 Outlet Flow Rate Range to 15 L min Air N gt Note You can open the flow valve beyond the indicated maximum flow of 15 L min to provide an actual maximum flush flow of 30 L min Bottle Tank Input Gases Air Medical Grade with Standard CGA 346 Fitting Nitrogen with Standard CGA 580 Fitting System Input Gas
19. y differ slightly in function This is because the blender dial face is only accurate if there 1s sufficient flow passing through the blender One port automatically bleeds a sufficient bypass flow to achieve this accuracy the bleed port while the other requires you to select flows above a minimum flow to obtain accurate mixtures the no bleed port The bleed port will automatically vent 2 5 to 3 5 L min of blended gas continuously out of the bottom of the blender whenever you connect a device to that port and your gas supplies are pressurized Detailed descriptions of each are provided here Left Side No Bleed Minimum Required User Selected Flow 3 L min Gas Vented none Notes All gas leaves the blender through this port so there is no bypass flow Right Side w Bleed Minimum Required User Selected Flow 0 L min Gas Vented up to 3 5 L min continuously Notes You must shut off your gas supplies when not using the system AND you have the flowmeter connected to this port There is a check valve that opens the bypass flow to be activated when you connect to the fitting on this port Other Notes DO NOT tape over or block any of the ports on the bottom of the blender DO NOT immerse the blender in any liquids DO NOT steam clean or autoclave the blender e Clean blender surfaces using a 10 bleach solution or light detergent in water Blender Maintenance The blender functions using various e
Download Pdf Manuals
Related Search