JP 2012-518388 A 2012.8.16 (57)【要約】 本発明は
Contents
1. 10 20 30 40 50 JP 2012 518388 A 2012 8 16 9 10 U l 20 30 40 502. o o o o o r4 A m F Ira a Ooo oO z SS ero _ 3 3 O 8 0083 El _ ee DE ms E _ a L3 3 _ en en O A o o HO Ea x SEE a oO 3 soon O 3 O O O 3 3 El Ot a Ot 3 E m 3 3 Ot Ot a 9 p 3
3. O O 4440000 10 20 30 40 50 16 JP 2012 518388 A 2012 8 16 u HHHHHHHHH
4. RS R5A Bis RSA SERE IEE 2 288 SE A 0 20 15 19 3 19 03 1 1 09 11 02205 0310 04 1 33 1 10 1 15 1 0430 06 10 34 1 1 09 1 3 10 1 10 15 1 1 17 2 12 23 1 2 25 1 1 34 1 1 BY 020 14 19 1 19 09 3 2 17 3 1 02 20 03 1 D 23 10 09 3 14 10 1 5 15 12 17 3 10 22 12 23 1 15 2 23 1015 25 1 3 34 102 FAGRSABLURBRET AE D A STEK 02 2 03 1 04 1 06 1 09 1 10 1 15 1 17 2 B ST
5. JP 2012 518388 A 2012 8 16 29 o o Q Q o ri N m st LA OO 9 Oo r oo Em oo r3 EJ r3 a a HE I a l O O ME ss E I Oo Oo LI LJ Oo O o ga r LI a a O ms nd o CI C O ze 9 O Oo r DI mm CI CI OG I OG I
6. JP 2012 518388 A 2012 8 16 13 U l 10 n O Ebo 200 790 20 30 40 50
7. JP 2012 518388 A 2012 8 16 63 l JO E o O
8. JP 2012 518388 A 2012 8 16 64 uui O nnin nonnnna D l nnn noo 65 JP 2012
9. O 00000 HHHHH JP 2012 518388 A 2012 8 16 61
10. 53 JP 2012 518388 A 2012 8 16 A 0 o A O U 0 HHHHHHHHA 000004 HHHHHHHHHHHHHHHHHH 0 00000000 HHHH HHHHHHHHHHHHHHH qien EEE EE EE lO O O HHH HH HHHHH HH HH HHHHHH HHHHHHHH O O 14 Bee ch ONE o ARERR PM PM 20 174 5 30 6 E956 23 143 0 40 5
11. 10 20 30 40 50 33 JP 2012 518388 A 2012 8 16 C nn m nn M 10 20 30 40 50 34 JP 2012 518388 A 2012 8 16
12. 10 20 30 40 50 JP 2012 518388 A 2012 8 16 5 10 IU ME o O 20 D n 30 IUD IUD 40 50
13. I00O000000000000000000000000000 n PME II RE 4 ST RE TE A mm HE Fm WR MA MB HA MB dA MB MA MB MA MB MA MB MA MB MA MB TM 0 0 2 gt a i F 2 745 1 05 gt 716 1 05 37 35 37 747 0 0 32 748 0 0 32 T4 0 32 37 488 74 1 742 1 0 E 35 43 2 05 32 32 a H9 4 25 Po pu g 730 1 0 35 77 2 1 37 37 I 737 0 0 i 738 0 0 RA 02 B 0 0 BB m 1 05 lt 3 RSA Rapid serum agglutination BA ID Mg 16s RNA PCR Mg MA MB MA MB
14. 5 A ST 26 1 26 2 26 3 ST MGA 0220 34 2 MGA 0220 34 2 MGA 0220 34 2 ATP OppD ATP OppD ATP OppD Gara X 10 20 30 40 50 JP 2012 518388 A 2012 8 16 35 10 20 30
15. JP 2012 518388 A 2012 8 16 62 IUD JO a
16. JP 2012 518388 A 2012 8 16 6 DU l 10 DU l 20 Ja a JO a JO E l 30 40
17. o o O 30 40 DU l DU l D l D 50 o O 0000 DOOODO o O 8 JP 2012 518388 A 2012 8 16
18. 14 JP 2012 518388 A 2012 8 16 A A O O uu O O O O O HHHHHHHHHHH O HHHHHHHHHHHH 10 20 30 40 50 15 JP 2012 518388 A 2012 8 16 JUDUDD
19. 10 20 30 40 50 43 JP 2012 518388 A 2012 8 16 D 000000 0000000 10 44 JP 2012 518388 A 2012 8 16 ZW x RU D D SD um x FH iii 0 25 0 0 5 0 25 0 0 5 0 0 0 257 50 11 41 8 37 6 2 ST 04 1 0503519 0250 05 0 25 0 0 25 67111 5
20. 10 20 30 40 50 11 JP 2012 518388 A 2012 8 16 10 20 30 40 50 JP 2012 518388 A 2012 8 16 12 10 20 30 40 50
21. JP 2012 518388 A 2012 8 16 18 10 n 20 30 40 50
22. 10 20 30 40 50 47 JP 2012 518388 A 2012 8 16 nn nn n nn 10 20 11 EE 0 MHB 0 28 14 2886 7997 ROR sen mam mes 1 Hee 382 41 53 46 106 12 34 7 9 2 iib Wi Ap3AS 42 5 5217 94 13 28 4 30 3 ST RK 387143 48110 104 15 3826 4 ST R 26 1 WIAp3AS 415 58 5049 100 13 3 6 H HHHH 48 JP 2012 518388 A 2012 8 16
23. P20 05 HHHHHH 54 JP 2012 518388 A 2012 8 16 17 16 P E956 0439 10 166 00238 00012 O23 10089 HHHHH 18 16 E956 AdppD AoppD E956 AdppD oppD 0 0003 10 0154 0 008 10 00001 0 000003 009 00065 00561 L 10145 0 4 HHHHH 19 E coli KBAR E956 oppD dppD HE BE Logtl Er LPTRERPTRE TRE Fi E 20 5 956 20 220 120 820 02 0000 225 010 8 1320 1250 45 AoppD 20 100 020 900 020 0000 143 000 280 620 DO P20 05 ZU 19
24. 30 40 DU l 50 24 JP 2012 518388 A 2012 8 16
25. JP 2012 518388 A 2012 8 16 CO CO L3 L3 10 20 30 40 50 20 JP 2012 518388 A 2012 8 16
26. Tem ss _ peaos aio GOOD ZU RY P ma App oo 0082 n n n n HHHHH poo 10 20 30 40 50 JP 2012 518388 A 2012 8 16 55 10 20
27. C C C C 40 50 C 36 JP 2012 518388 A 2012 8 16
28. JP 2012 518388 A 2012 8 16 41 DU l 10 C HHHHHHHHHH H 20 30 9 RSA M gallisepticum vo 0 I NA UU N rm ST 04
29. JP 2012 518388 A 2012 8 16 45 10 20 C C C 30 C C 40 C C 46 JP 2012 518388 A 2012 8 16 10 RSA M gallisepticum RSA MA MB ug
30. 0000 INKL R pISM 2062 soso sos sososos sososos sososos 1 2 lle e sv OD 0 l iH S EN Pa de gi x pa v Y RN Q DNA ST A TILA B a 9FU6 mke NN 288 NG a SENS TINTA B 2 AI ERRE 14 u AST
31. JO a 20 30 o O DU l 40 50 n y o H DU l H O JP 2012 518388 A 2012 8 16 23 paa lu u ng 0 0 10 20
32. O GOOD 0o 10 20 30 40 50 21 JP 2012 518388 A 2012 8 16 HHHHHHH O HHHHHHH 0 10 20 30 40 50 JP 2012 518388 A 2012 8 16 22 10
33. Ing HHHHHHHHHHH l HHHHHHHHHHH A O m r3 m m D C Od x x C E C C A A 10 20 30 40 50 JP 2012 518388 A 2012 8 16 52 10 20 C BU l 30 40 50
34. DagagmggB mmupBaug uuuug uusuuuu mauagumBauuuUuuldtbtE u HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH nnnnnn nnn nn nn nn nn nn nn nnn nn nn nn 10 20 6 ST ST 26 1 2 3 MGA 0220 ATP OppD 09 3 13 1 2 3 15 1 2 3 17 3 25 1 2 3 34 1 2 3 30 A GE EE El 37 JP 2012 518388 A 2012 8 16 IDDU 7 RSA RSA REE 0 2 4 208 488 LES A 080 700 89 Q8 210 09 08 160 200 280 078 10 20 02 A B 18 1 1902 2006 211 08 04 06 09 10 2406 26 1 102 28 2 15 17 22 23 25 3160 3201 3501 3801 33 34 39 1 B OM 610 1 040 210 111 010 1205 2009 280 070 10 20 140 16 1 2066 2701 2802 C 09 sno 900 ov 0 240 OH 121 010 0268 10 1208 16 3 18 1 2007 1301 14
35. 20 30 40 50 JP 2012 518388 A 2012 8 16 49 10 20 13 5 3 WAKanFshort cgttggctaccoq 50 JP 2012 518388 A 2012 8 16 PCR WE_dppD5_kanF ccgtcagcgagcga tcaggtcgg WF_dppD3_kanR tttatgg tat ggtcgtact ttcatag tgatatt 77 ttgacctgctga 78 dppD Kan 5 LLagactgggegg cgggttaagcaggcagccgttcggg 79 dppD Kan 3 tgcccgaagcccaacc WS
36. 50 JP 2012 518388 A 2012 8 16 7 10 pod o O 20 DU l nn on Nn I BU l o O
37. 10 20 30 40 50 JP 2012 518388 A 2012 8 16 31 10 20 30 40 50 o O C 32 JP 2012 518388 A 2012 8 16
38. 20 269 29 6 17 943 7 AdppD 19 19 143 0 40 5 255454 0 19 3 3 1 _AoppD 20 20 155 0431 1 255 49 0 18 442 4 __ P20 05 T OD 15 14 P f AdppD AoppD E956 AdppD oppD 0 006 0 053 0 007 0 302 0 257 AdppD 0 237 0 995 AdppD 0 990 AoppD 0 291 000000 316 E coli E956 oppD Logo FE LPTSERPTISERE FR mene 20 5 20 220 300 1120 420 040 0 048 0004370 020 0 0 0 0 0 E956 23 1123 1103 21203 303 048 0 400y 2480370 17 23 a AdppD 19 10 19 11 19 16 19 819 208 0 400 1930370 11 19 1040 16 AoppD 20 920 720 1020 420 000 0 400 085 0370 920 0 0 0 20
39. PCR ST 56 JP 2012 518388 A 2012 8 16 Figure 2 bp 587 298 174 102 80 00 Figure 3 bp 102 80 E o sa raq genera T m bp 123456 57 JP 2012 518388 A 2012 8 16 A A u E j 4 i BEN ew po i u 3 H se M i R i E ves i lt 2 m s i edi IN ano 2 zo3 s eses vea asos E E i Le m sa A i fn 0 d d ds did e 1 2 4 5 6 7 8 8 0 gt epee mU I 3 3 4 B o E se i 7 i 6 i B x E 1 nm E DERE FOR i 3 m 4 i ae E E A ei 3 d i i 7 i P 2 i HF a 025 i he p 0 i eis i i eon L gt de 44 CA T a 7 li sase ew sere sees I i 2 3 4 A MO yt ws TX WA WV kbp 2 3 2 0 1 5 LO 0 8 58 JP 2012 518388 A 2012 8 16 dppD omo kbp somp EP 6 0m E 50m 40m 30m 25m 20m 15m 10m 123123123 12518388000001 app
40. 10 25 JP 2012 518388 A 2012 8 16 1 DNA ID DNA P2 P4 ID bp 01 Ptag5 CCACAGCGCTITCTCCCGCECCCAATCACCCACCCICAAT 1 40 80 02 Ptag7 AGCTACAAGCGAACTACCICCCGCTATCACCCGCTCGCA 2 39 79 03 Ptag9 ACCCATACCGARACAACTCTCCCGCAAGCGCCCAACCCCT 3 40 80 04 PtaglQ ATCGAGGTATCGGTTGCTAGGGGGTACGCTAGGGGGAGTT 4 40 80 4705 Ptagl2 5717 R3 9 Rt 5 06 Ptagl7 AGAGCTTGAAATATTGGGCGCGAGTGTTCAGGGTTGGGGT 6 40 80 07 Ptag20 AGATGAGGGGCTGGAGCTAGAGATGCTGATTTAGCGGAGG 7 40 80 47 08 IR1 5 3704 Ptag 10 4 2509 1R1 10 ATCTATCCACCGATACTCCTCTCAATCTAGCGCGATACCT 8 40 80 2510 1R1 20 GTCGTGCGTGGGAGAGGGCTATGGATGGTTGATGAGGGGT 9 40 80 11 1R1 29 CTATATCTACATCTCTCACCCGAGCGCTCCCCAAACCGCC 10 40 80 12 R2 3 CTCCACCICTATCICICTATCCCCACATAGACCCACCICC 11 40 80 13 R2 5 CCTATCACGCTICCTCCTTCAACCTAACTCCCACTAGAGCT 12 41 81 8514 R29 ATCTCCCTATCTCCCTCGAGCICITGCCCICTAACAAGCT 13 40 80 8515 R2 18 GTAATTCGTTCGGTATTTATTGGTCTGGCGGTAGGTAGTAG 14 41 81 16 R2 22 CTCCCTCTACTCCCCCGATACACACCCCTACCCACCAATCC 15 41 81 4517 R3 0 CTGGGGGTGGAGAGGTCGGTGATTAGGAGTCTCGGTGTTA 5 40 80 8 R3 17 AAACCCCTGCCACGTCAGCGATCTCCCTCACACTAGCTCT 16 40 80 19 R3 23 CICCCATTCCCACTCACCCGATCITIECCACICC
41. FE az amp HHE SHE sS AE 26 1 Ap3AS 26 1 Ap3AS 1 020 020 0 20 0 20 0 20 0 20 0 20 0 20 0 20 2 Wt Ap3AS I 030 2020 520 120 19 20 0 20 2 20 0 20 10 20 3 STEREO 020 1620 0 20 1 20 2 20 1 20 0 20 2 20 0 20 4 ST 26 WLAp3AS 020 2020 0 20 0 20 1 20 0 20 0 20 0 20 9 20 Ap3AS C RSA G MA gallisepticum ST 26 1 AP3AS PCR L L3 L3 EJ L LJ D D oana D L LJ D E E LJ DJ D MOO D MOO D L L3 L3 L3
42. PCR bp 00 o O n n JP 2012 518388 A 2012 8 16 26 3 R Q rt O 3 a 3 ELE oY C OO ee sess oo sy e E I p E I Y 3 Ol Y E I a E I a E I E I Y 9 OG I Y m a I
43. 2 1 Q3 AU 74 100106002 EM RZ 74 100120891 REE 54 BHO BRED I FY 520000 IHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HHHHHHHHHHHHHHHHHHHHHHHH 0000000 JP 2012 518388 A 2012 8 16 10 20 30 40 50 JP 2012 518388 A 2012 8 16
44. 2 STM P2 P4 IGstmGenmeF3 MG F MG R EOGentSpelRev EPGentSpelFor M13 For M13 Rev STMO2 B Rev STMO3 B Rev STMOA B 1 STMO4 C Rev STM06 A Rev STM09 B Rev STMIO Rev STM13 JA rev STM13 JB for STM13 KE STM13 KE C STM13 KE C 1 STM13 KE C 1 Rev PCR PCR DNA ST PCR Mg 16S PCR Mg 16S PCR PCR PCR DNA DNA ST RA PCR ST PCR ST PCR ST PCR ST 26 PCR ST PCR ST PCR ST 13 ST ERK 13 ST ERK 13 ST 13 ST 13 Ap3AS PCR 38 ps o 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 27 JP 2012 518388 A 2012 8 16 5 3 bp ATCCTACAACCTCAAGCT 18 ATCCCATTCTAACCAAGC 18 GGACTGTTATATGGCCTTTTTGGATC 10 26 GTTGCAAATCCGTAAGGTGG 20 TTAGCAACACGGTTTTAGAT 20 actagtATCAGCCAATCGCTTAATTG 26 actagtCTGAGTTTATGGAAGAAGTT 26 GTTGTAAAACGACGGCCAGT CAGGAAACAGCTATGACC TICAATTCGAAAAATGAGTT ACAGCTTGACGTTTTCCA CGGGGACACAGTAAGGCTA
45. DU l o O uui 10 JP 2012 518388 A 2012 8 16
46. JP 2012 518388 A 2012 8 16 19 JP A 11 2012 518388 P2012 518388A 43 24 8 16 2012 8 16 51 Int Cl Fl C12N 1 2 2006 01 C12N 1 20 ZNAA 4B024 C12N 15 09 2006 01 C12N 15 00 A 4B064 C12N 1 21 2006 01 C12N 1 21 4BO65 A61K 39 00 2006 01 A61K 39 00 Z 4C076 A61K 39 02 2006 01 A61K 39 02 4C085 69 21 2011 550380 P2011 550380 71 HERA 509336266 86 22 22 2 17 2010 2 17 85 23 9 9 2011 9 9 86 PCT AU2010 000172 2351 87 W02010 094064 DA 87 22 8 26 2010 8 26 31 2009900736 32 21 2 20 2009 2 20
47. 04 3 09 3 11 3 22 1 23 1 25 1 33 1 34 1 A BB 1 2 ST HHHHHH JP 2012 518388 A 2012 8 16 39 10 20 30 40 50 o O o O C C JP 2012 518388 A 2012 8 16 40
48. O o p LI O HE I 30 JP 2012 518388 A 2012 8 16 E u EE E x O 3 ST 02 1 68 3 03 1 16 0 04 1 0 2 06 1 34 6 09 1 60 3 17 1 80 1 19 1 88 6 32 1 52 0 35 1 76 4 37 1 20 5 jl SSE i ge VE ke s
49. 3 10 20 30 40 50 D 4 JP 2012 518388 A 2012 8 16
50. HHHHHHHHHHHHH HHHHHHHHHHHH HHHHHHHHHHHH iDnggaagmmuu OD 10 20 30 40 50 JP 2012 518388 A 2012 8 16 17 10 U B 20 30 n 40 50
51. IHHHH ZN BK SDY um a EM sag 2 WiApAS 25053 25 05 3 20 3 25321001 206t1075 17398 3 ST 26 04 0255 0 0 05 00 075 tilt see 28t6 4 STEAM WtAp3AS 0 9 1 0 0 0 25 0 0 0 44 14 2818 2513 ADAS D
52. LH LH 220 120 20 2010 12 20 HHHHHHHHHHHHHH 59 JP 2012 518388 A 2012 8 16 60 JP 2012 518388 A 2012 8 16
53. 01 16 3 1800 271 28 1 2010 2445 27 6 2865 3611 380 RSA C i 1 2 A 2 C 3 30 40 50 38 JP 2012 518388 A 2012 8 16 oa oa L3 L3 LI E ESI E D
54. 1 ST 33 1 ST 03 1 ST 26 1 ST 18 1 ST 8 20 1 ST 22 1 Ap3AS ES RSA 2 0 20 0 20 0 20 1 20 0 20 20 20 20 20 0 19 18 18 Az 0 20 0 20 0 20 1 20 4 20 5 20 6 20 0 19 11 18 JP 2012 518388 A 2012 8 16 MA MB SE SE 0 20 0 20 0 20 0 20 0 20 0 20 0 20 0 20 0 20 0 20 0 20 2 20 0 20 2 20 0 20 5 20 1 20 6 20 1 20 10 20 5 20 17 20 720 19720 7 20 20 20 8 20 20 20 0 19 1 19 0 19 3 19 9 8 18 18 10 18 15 8 TLERSABLUREREAIPT SIS E 1 8 2 9 2 8 ST
55. 10 2006 01 39 108 Dogo 3904 2006 01 39 04 OOOO 392 2006 01 39 295 DDDD 32 20600 39 12 DDDD 3739 200601 39 39 0000 4726 2006 01 47 26 O000 4742 2006 01 47 42 DDDD 4702 2060 47 02 O000 471 200601 47 12 OOOO 4722 20060 47 22 Dogo 4718 2006 01 HHHH 4718 pogo 4710 200601 47 10 OOOO 4 36 206 HHHH 47 36 UUUU 3704 2060 31 04 UUUU 3v12 20601 3 12 0000 3704 2006 01 000 37 04 O000 39215 200601 39 215 UUUU 3917 X 2006 01 39 17 ogogo 2402 2006 01 21 02 0 80 0 O AP BWCH GM KE LS MYNZ NA SD SL SZ TZ UG ZM ZW EA AM AZ BY KG KZ M RJ TJ TM EP AT BE BG CH CY CZ LE EK EE ES Fl FR GR FR HJ IE IS LT LT LU LV NG MK M N NO PL PT RO SE SI S K SM TR OX BF B CF G3 0 M G QN GQ QM M NE SN TD TG AE AG AL AM AQ AT AJ AZ BA BB BG BH BR BWBY EZ CA CH Q NOR QJ CZ LE K EM DO LZ EG EE EG ES Fl GB OG GJ GM GL FN FR HU ID TE IN I S J P KE KG KM KN KP KR KZ LA LC LK LR LS LT LU LY MA M ME MG MK W WM W MZ NA NG N NO NZ OM PE PG PH PL PT RO FS RU SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US Z G W ZA ZM AN 79000 UU HHH uuu HHHH HHH U 72 72 L
56. 3 1 409 3 ST 33 1 050853 035025 00 025 73 32 gin BEB 4 ST 03 1 1 023 3 03750 15 0 250 1 5 89 45 54 12 46 22 5 ST 2 0 50 29 0 25 0 0 0 2 6424 49 4 44 2 6 STZ SIS 0250 10 0250152 025 0 15 62115 53115 49415 7 STEREO 0250 15 0125 15 0 125 0 10 36420 49 23 51 19 8 ST 22 050 1 0 25 0 1 0 0 0 25 641 13 49 8 3018 9 Ap3AS 15 1 3 1 50 0 5 3 1 50 0 25 3 168 70 1534 84 120 56 SD F oa a O oana TE L1 xog
57. 518388 A 2012 8 16 00000000 INTERNATIONAL SEARCH REPORT International application No u DER PCT AU2010 000172 A CLASSIFICATION OF SUBJECT MATTER Int Cl I C12N 1 36 2006 01 A61K 39 02 2006 01 CI2N 1 20 2006 01 According to International Pat nt Classification IPC or to both natiorial classification and IPC FIELDS SEARCHED Minimum documentation searched classification system followed by classification symbols bi asia searched other than minimum documentation to the extent that such documents are included in the fields searched Electronic data base consulted during the international search name of data base and where practicable search terms used WPI BPODOC HCAPLUS BIOSIS MEDLINE Keywords ABC transporter attenuated bacteria and like ierms C DOCUMENTS CONSIDERED TO BE RELEVANT Citation of document with indication where appropriate of the relevant passages Relevant to claim No WO 2002 034773 A2 IMPERIAL COLLEGE INNOVATIONS LTD 2 May 2002 The whole document but particularly abstract page 3 lines 10 17 and 22 27 page 6 lines 3 17 page 6 line 13 page 7 line 20 Table 2 page 21 lines 16 32 page 25 line 25 claims 7 12 14 22 and 23 R SHINA G M S ET AL Identification and characterization of a Brucella abortus ATP binding cassette transporter homolog to Rhizobium meliloti ExsA and its role in virulence and protection in mice Infection and Immunity 2002 vol 670 no
58. 9 pages 5036 5044 The whole document but particularly abstract page 5037 column 1 paragraph 1 page 5037 column 2 paragraph 2 page 5038 column 1 paragraph 2 page 5042 column 1 paragraphs 2 and 3 table 2 figure 6 page 5043 column 2 paragraph 2 WO 2004 089408 A2 XENOVA RESEARCH LIMITED 21 October 2004 1 9 15 38 The whole document but particularly abstract page 4 lines 14 22 Experiments I and 2 claims 4 and 7 Firther documents are listed in the continuation of Box C See patent family annex Special categories of cited documents document defining the general state of the art which is T later document published atter the international filing date or priority date and not in not considered to be of particular relevance conflict with the application but cited to understand the principle or theory underlying the invention carier application or patent but published on or after the X document of particular relevance the claimed invention cantot be considered novel international filing datc rio be considered to involve an inventive step when the dooument is taken alone document which may throw doubts on priority claim s Y document of particular relevance the claitned invention cannot be considered t or which is cited to establish the publication date of involve an inventive step when the document is combined with one or more other another citation or other special reason as specified u such documen
59. A CGCATIGATICCTACCAC AACATGGATTAGACGTTTGC 20 TGCCTTTCTTAATAGTGCTCA 21 TIGIGCCCATICGITAST 18 TTAATACGCCTGGGTAAGGTCG 20 18 20 18 20 20 18 22 TATCTATCACGTAATTGGAATGC 23 TCGCTATAACATTTGATTTAG 21 30 CATTTTGATGITIGCGTCA 19 CTTCAAGTTCTCTGTGG 17 CCACAGAGAACTIGAAG 17 28 JP 2012 518388 A 2012 8 16 STM13 KF ST 13 60 CCGTTTTTCTTTTATTCGTATTATC 25 STM13 KF C ST 13 61 TATAAACCTGGTACGG 16 Ap3AS PCR STM13 KF C 1 ST 13 62 CACACTGAAAGTTATATTA 19 STMI3 KF C 2 ST RA 13 63 CTCACTATATAAAATAGC 18 STM13 KG ST 13 64 CAGAAGATAAGTCTTTAACAG 21 JX STMI7 ST 2 PCR 65 CTAGAAGAAGAAGAAGAGGTAACGAAGC 28 STMIS Rev ST 24 PCR 66 AGCAAAATTTCCACCCAAGA 20 STM20 Rev ST PCR 67 GAGACATCAATCGCGGTTTT 20 JZ STM22 ST PCR 68 CTCAATTGAAGAATTATATGATG 23 STM23 B Rev ST PCR 69 TTAACCCCATTCTTGCAG 18 STM26 Rev ST PCR 70 CATCCCACCTGAAAACTCGT 20 Ap3AS PCR STM26 genome Ap3AS 71 GATCGGTGCACAGATTAAAG 20 PCR KB STM33 ST PCR 72 ACTACACGGTAGTTAGTAC 19
60. AAACCC 17 40 80 8520 R3 24 ACTACGACATATCCTACACTACAACGCTACATCCCGCGCT 18 40 80 2521 R3 33 SGAGATGTTCAAGTTAGEGAGGTGGCTGTAGCTAGAGAG 19 39 79 4522 R3 35 AKCGGTATGICGGTAGAGTGGTITGGGCTACGAGGAGAGCG 20 40 80 23 R3 47 AGAGCGGGATACTGTAGTTATCGTTAGCTCTTGTGGTTTTA 21 41 81 24 R3 5Q AGAGATITATCGATAGCGAGGICGIGCTGGCGAGTGGGIG 22 40 80 25 R3 54 GICGGGAGGGAGAAGATCAGTGTGTTG 23 2 67 26 R3 57 AGAGAAGTATCGGGATGTCGCTCGCGCTTGTGTGGGGGAA 24 40 80 2 R3 66 GTATGGGTAGGGGGAGAGGGAGCTAGTGATTTACAGGGAT 25 40 80 4728 R23 GGCGGGGTGTAGAGAGATTGGGAGGGATGTACAGCGGGTT 6 40 80 2529 RIG CGGGAGATAGAAGTTTTGAGAGGGAGAGTTAGATTGAGTG 97 40 80 2530 R32 GGTGTGGGCGCTTAGTTGGGCAAGCTTGCGTGGTGGGTCT 28 40 80 443 R43 AGGTAGATATCTATAGAGGTAGTTAGGCTGGGGATCGAGGA 20 41 81 4732 RAG CTCTATCCATCTCGTAACCCATATCGATAGATCGCAATAC 30 40 80 2533 R32 CGATACAGACCCGAAATCTCTCAACCCCGCACGCAAACT 31 39 79 34 R56 ATCTAGCACCAACACTATCCATAGCCCACTATATATATIC 32 40 80 2535 R62 GGGGGTAGAGCGTGAGCGGGATGTGTCGGGGGGIAGGGAG 33 40 80 4736 R75 AAAGCTCTGGIGTCTGGGCGCTAGGGAGGGATCGAGGAGG 34 40 80 37 RIT CCCACACTCTCCGACCCCTCAGATCCCCCCCGCCAACCCT 35 40 80 2538 R79 AGGGCGAGATGTAGGTGTIATGGAGCTGGGGATGGAGATAA 36 40 80 4739 R80 37 41 81 CCAACTCCTCCGTACACCCCCGCTAGCACCCCAATCCCTCG DNA P2 P4
61. OO IUD 000 HHHH 0000000 HHHHH 00000 000 48024 A01 BA31 BA32 GOA DO DO DAO7 DO FAM GAIL HAO1 4BO64 AG1 A22 BL Co2 AY 24 DV 4BO65 AAO1X AAO1Y AALSX AA5Y AA23X AA23Y AA26X MYOY AAG6X AA36Y 69 JP 2012 518388 A 2012 8 16 AA37X M3TY AMIX AM1Y AMOX AA46Y AMOX ANIOY AA55X AA55Y ABO1 ARO BAO2 BA4 BAG CMS 40076 ANI2 AM4 A25 AM9 BBO1 BB13 BBIS BB16 BE BE24 BB25 BB31 007 32 0535 2 OBI 088 ODA 0422 LD60Z LD56 LD6 EE30 EE41 FF61 40085 AAD3 A38 BAD7 BAo9 BAL BAI2 BA4 BAU BAIS BAIY BAO BA21 BA24 BMS BA51 BA59 BA 1 BA BA82 007 E01 LD02 LD62 EEO1 EEO3 EE06 FFO2 FFO3 FF11 FF12 FF13 FF17 FF18 FF19 FF20 GO1 GD3 Galo
62. inuation of second sheet July 2009 67 JP 2012 518388 A 2012 8 16 International application No PCT AU2010 000172 INTERNATIONAL SEARCH REPORT _ Information on patent family members This Annex lists the known A publication level patent family members relating to the patent documents cited in the above mentioned international search report The Australian Patent Office is in no way liable for these particulars which are merely given for the purpose of information 206 Patent Document Cited in Patent Family Member Search Report I WO 2002034773 AU 95795 0 CA 2426738 EP 1330473 Us 2004116661 US 2009280141 de WO 2004089408 US 2004241190 WO 2006089121 US 2009162401 Due to data integration issues this family listing may not include 10 digit Australian applications filed since May 2001 j END OF ANNEX Form PCT ISA 210 patent family annex July 2009 68 JP 2012 518388 A 2012 8 16 SDI AL IHHHHHHHHH OOOO 3910 2006 01 HHHH 3910 UUUU 397106 2006 01 OOOO 39106 OOOO 39085 2006 01 39 085 Dogo 3908 2006 01 39 08 OOO 39112 2006 01 39 112 UUUU 37118 2006 01 39 118 Dogo 39102 20601 39 102 OOOU 39104 200601 39 104 OOoOg 39
63. oppDFor gcactgctgaacgtgaaaga 80 op WToppDRev WU1oppDRev Kan cataaaaccgcccagtctattttta 82 oppD 5 tcgagcatc WV2oppDFor Kan tatgaaaggttgggcttcgtcgacc 83 oppD 7 44 3 gctgattg Sidfwdsec bwd siderophore ctcacgggtgaaaatatttt 85 iucA 16Sfwd gctgacgagtggcggacggg 86 16s RNA 16s RNA nenn D0O00000000 000 O000OQ0000e000000000 E u a nnm _ ana ge A C H H EAL RE du Ep tt ate anes pe AG ernnnnn H rm rm r3 m ec rm rm rA m rm rm O rm rm rm Bi rm C C r1 UP Gp EI MM nm F1 m Frnmnrn Tr x Mn nm C nn non non m 10 20 30 40 50 JP 2012 518388 A 2012 8 16
64. ts such combination being obvious to a person skilled in the art document referring to an oral disclosure use exhibition orother means document published prior to the international filing date but ater than the prlority date claimed Date of the actual c mpletion of the international search Date of mailing of the P APR search report 8 April 2010 ak 8 APR 2010 Name and mailing address ofthe ISA AU Authorized officer AUSTRALIAN PATENT OFFICE Julie Christie PO BOX 200 WODEN ACT 2606 AUSTRALIA AUSTRALIAN PATENT OFFICE E mail address pct ipaustralia gov au ISO 9001 Quality Certified Service PRES 461 262437993 Telephone No 61262832463 document member of the same pat nt family Form PCT IS 210 second sheet July 2009 66 JP 2012 518388 A 2012 8 16 INTERNATIONAL SEARCH REPORT I International application No i PCT AU2010 000172 c Continusiion DOCUMENTS CONSIDERED TO BE RELEVANT B WO 2006 089121 A2 KENT SEATECH CORPORATION 24 August 2006 The whole document but particularly paragraphs 0048 10051 0067 0073 Example 2 cl ims 22 and47 GARMORY H and TITBALL R W ATP binding cassette transporters are forthe 1 9 15 38 development of antibacterial vaccines and therapies Infection and Immunity 2004 vol 72 no 12 pages 6757 6763 Page 6760 column 2 paragraph 2 page 6762 column 1 paragraph I Form PCTASA 210 cont
Download Pdf Manuals
Related Search