Page 1 Page 2 Page 3 Page 4 Page 5 (5) 平成25年度行政報告等
Contents
1.2.
3. 1 2 3 4 5 6 7 8 9 10 MR
4. 44 8 8 24 11 80 0157 026 0111 8 90 43 63 Conditional logistic regre
5. 1 22 9 10 286 26 3 26 36 2 2002 55 3 p191 198 3 2010 54 2 p93 105 ICP MS
6. 3 ELISA PCR 1 ELISA
7. 24 3 15 0315 _ 2 _ 4 0980 gcm3 0Botg 1L 0 994gcm3 7 6 Bqgkg 0 901 gicm3 550 Bqkq 40K 0 506 qcEm3 24 kn 4 0 453 g cm3 520 Bqlkc 2 2 000 10 20 000 4 334Cs 137Cs
8. 4 25 Evaluation of a new immunochromatographic assay for rap1d identification of influenza A B and A H1N1 2009 viruses CHnical evaluation of highly sensitive silver amplification immunochromatography systems for rapid diagnosis of influenza Characterization of neuraminidase inhibitor resistant influenza A H1N1 pdm09 viruses isolated in four seasons during pandemic and post pandemic periods in Japan A MR 1 5
9. 7 2 6 1 6 2 1 2 1 3 0 7 1 1 6 am 1 7 1 6 7 1 3 cr
10. P ND 1ug g 3 7 1 8 3 9 3 9 3 1 1 1 1 1 4 6 5 4 6 5 8 5 7 1 7 2 1 7 7 9 1 6 1 3 3 0 1 8 2 4 2 8 1 4 ug g x10 x10 x10 x10 x10 ND ND x10 X10 x10 x10 X10 x10 x10 x10 x 10 x10 x10 x10 x10 x10 x10 x 10 3 8 x10 1 2 1 4 ND x10 ND ND ND ND ND ND ND 6 5 ND ND 8 1
11. H 2 0 H 2 0 7 2 SOP
12. 1 25 75 2 25 OE 0 2013 0 72 a 72 H25 10 24 NT H26 11 7 50 H26 11 8 5 HO 50 3 25 H25 6 27 H25 6 27 H25 6 27 H25 6 27
13. 034Cs 137Cs 1 134Cs 137Cs 1 5 1 Bq kg Cs TCs 100 50 50 19 40 40K Cs TCs 20 10 10 20 4 000 2 000
14. 25 2 20 ELISA 26 2
15. 2 PCR 20 PCR PCR 2 PCR 1 2 DNA 1 PCR 2 PCR 1 PCR A No 8 No 39 DNA A No 8 DNA Agogo 1 1 0 69 PCR No 39 DNA 2 4ng unL PCR
16. ELISA Gly m Bd 30K Gly m Bd 30K 9 3 8 10nug g 1 8 7 No 37 6 5ug g No 37 ELISA 2 No ng mD ng mL 6 A 9 53 0 95 B 10 39 0 15 102 32 9 61 0 91 87 33
17. 1 150 0ppm HP 3 MW ICP MS 1mL 50mL 10 Me
18. P 111 119 2014 8 2014 Vol 29 Suppl I JOHNS 30 11 1553 1555 2014 33 2 23 27 2014 Uptodate 2015 P 67 72 2014 12 142 12 2689 2692 2014 Neurology 2014 82 7 564 72 J Clin Virology 59 132 134 2014 Vaccines 32 4253 4258 2014 Jap J Inf Dis 67 6 495 502 2014 PLoS ONB 9 3 e92519 doi 10 1371 journal pone 0092519 Published online November 25 2014 DOI 10 7883 yoken JJID 2014 027 Journal of Infection and Chemotherapy 2014 20 12 789 793 lt ll NH g a ill NH HU NH Takanashi Taneichi H Misaki Yahata Y Okumura A Ishida Y Miyawaki T Okabe N Sata T Mizuguchi M Miyata L Hanaoka N Okabe N Fujimoto T
19. No 32 PCR PCR 2 Q amp A 1
20. 4 4 4 4 4 4 4
21. No 25 29 10ng g 10ng g 1 ELISA 1 2
22. 55 1 p 41 54 J Infect Chemother 2013 19 4 633 8 J Virol Methods 2013 1941 2 123 8 Influenza Other Respir Viruses 2013 7 6 1390 9 2013 34 10 311 312 IASR Vol 34 p 310 311 2013 10 2013 16 3 209 217 H7N9 E 5 2 2013 70 2 399 405 ICT 9 76 81 2014 411 7 12 2014 78 70 74 2014 The TRC News No 118 Mar 2014 2 3 203 211 2014 67 515 520 2014 73 3 379 383 2014
23. HP 2 MW 2 4 2 HP MW ICP MS HP 106 2 114 4 103 8 110 4 95 8 103 2 61 4 180 6 4 MW 97 7 104 6 90 1 100 0 95 8 101 4 89 7 94 7 5 4 n 5 a 106 2 1 9 103 2 2 9 129 95 8 3 6 0 1ug g 82 5 100 5
24. 1 7 5 5 2 GC Ee EL iT 1 i EI TE FE NN OH LD ED EE NE DE EN ET UE 1 gm F PD 1 EE te RT 1 C 1 8 2 1 8 3 1 0 2 H2 0
25. PCR DNA 1E MR IgM 25 10 24 72 1 23 1
26. ELISA PCR Me 1 39 1 9 No 1 5 No 4 6 9 2 1 ELISA FASTKIT Ver II RLHSA C 1575 ImnmunoWash BIO RAD Multiskan FC Thermo Masterplex Reader Fit Version2 0 2 1
27. p75 p76 p77 ICP MS p81 p83 p86 2 p88 mm p90 TB NR p92 Ch amydophila psittaci
28. 10 2 40K 40K 3 6 1 5
29. gt meg ng 38588 il 283 64 1 283 54 355 58 0 iE 39498 395 19 1 Er 1 00 3 0 1mg kg 1 8 1 4 4 1 8 30 2 7 n 3 5 102 96 WI 9 75 80 24 90 78 30 90 il 4
30. MW 1g 1mL 6mL MW 1 50mL ye 1 6 iooo ioo 0 9 5 1 11 1levlw 2 5 1 ICP MS 2 3 6 2 ICP XSTC 760C SPEC 3 2 ICP MS 3 HTP425AA MVW START D ICP MS
31. iCAP Qc HP 10g 5mL 3mL 6 MW ICP MS 20 9 26 0926001 1 1 1 2 5 3 1 5 1 1
32. 1 6 000 2 4 6 8 10 12 18 15 18 2 2 000 x 1 000sec 134Cs 3 0Bq kg 137Cs 137Ce 2 5Bq kg 2 3 3 134Csg 137Cs 2 0Bq kg a a 8 000 FF 3 LU 2 000 134Cs 3 6Bq kg 137Cg 2 9Bq kg 5 kk gt i ty EF mm 134Csg 137Cs 2 0Bq kg 16 000 2 4 10 12 14 16 18 20 x 1 000sec 1 4QK 0
33. T 2 HT 2 3 O157 2 O157 87 25 25 25 25 25 25 25 4 4 4 4 4 4 4 74 74
34. 2 1 g 10 ng 10ng g Re a 1 No CO PR OO MP ho O IO CO MD OO OO NN Oo OO Pk OO MD 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 A B A B A B A B C a 0
35. 1 134Cs 137Cs 134Cs 137Cs 2 000 1 2Bq kg 34Cs 137Cs 20Bq kg 4 000 C84Cs 137Cs 2 0Bq kg 20 000 da 0 3Bq kg x Ub 9 EE 1 TE 2 000 134Cs 2 2Bq kg 137Cs 1 8Bq kg 5 a a 1 1 5 2 15 em k 34Cs 137Cs 2 0Bq kg
36. p94 25 9 21 74 MR 39 MR 12 14
37. 2 0 2 H 2 0 re H 2 0 2 5 3 2 6 50 200 R SD lt 30 2 1 6 7 2 0 EE fF a a 0 Em EE 3
38. 2 Q amp A 2013 2014 8 i 1 1 2 2013 Clinical and radiologic features of encephalopathy during 2011E coli O111 outbreak in Japan Echovirus 3 as another enterovirus causing jife threatening neonatal fulminat hepatitis Recent progress and concerns regarding the Japanese immunization program Addressing the vaccine gap Construction of New Primer Sets for Corresponding to Genetic Bvolution of Human Adenoviruses in Major Capsid Genes through Frequent Recombination Bstimating the Risk of Parvovirus B19 Infection in Blood Donors and Pregnant Women in Japan Kudoa septempunctata induced gastroenteritis in humans after founder consumption in Japan A case control study Abnormal behavior during influenza in Japan during the last seven seasons 2006 2007 to 2012 2013 KN 2 5 537 543 2014 Pl 3 2 29 31 2014
39. 6 7 RSD 13 7 7 5 3 3 lt H20 gt gt gt gt EE r ma mL mL gt Im_ HL C CR HJ 5 gt mm a NN mw me I wm 1 wm lj 1 ww cc rppcme 2 H20 3 gt
40. 28 58 106 26 26 75 UI 2
41. 4 1 1 25 H25 6 5 H25 6 6 H25 6 27 H25 6 27 H25 6 27 H25 6 27 H25 6 27 H25 6 27 H25 6 27 H25 9 21 H25 9 21 H25 9 26 H25 11 1 H26 11 21 H26 11 22 H26 2 6 H25 2 7 H26 2 6 H26 2 7 H26 3 7 H26 3 15 1993 2012 O0157 TB 20 24 O157 MR GI 6 EHEC EPEC RFLP intimin
42. ELISA 10ng mL 1 aay eR x 100 10 3 PCR DNA GMquicker 3 1 2 DNA GMquicker3 Ver1 1 1 No 20 28 37 2 No 4 8 11 17 23 30 32 34 36 3 No 6 24 25 33 38 39 DNA PCR PCR PCR Veriti200 ABI
43. RSD 1 9 11 1 RSD 2 6 16 0 80 120 RSD 15 RSD 20 6 O 6 9 6 a 0 a RSD RSD a ee ie se6 0 0960 960 57 ieo 00906 906 23 57 0 0945 945 33 eo 00989 989 69 8s5 4 26 4 23 71 7 7 ICP MS ed 11213141slslzlsl 9 io iuili2 i13 14 15 16 17 18 1 He Ec Nolrlve a ol Y Zr NS Mo Tc Rh Pd
44. 1 1 NT ein ELISA 23 1 05ng g 10fg g 0 ng g 35ng g ei tdi en en ELISA 10ng g 100
45. 6 91 0 72 62 34 7 08 0 29 68 35 8 52 0 85 36 8 44 2 08 64 38 8 16 0 59 76 39 7 84 0 29 76 4 1 3 9 62 102 2 ELISA 50 150 No 33 34 36 62 68
46. 17 427 429 2014 Mitamura KKawakami C Shimizu H Abe T Konomi Y Yasumi Y Yamazaki M Ichikawa M Sugaya N Mitamura KShimizu H Yamazaki M Ichikawa M Nagai KKatada Wada A Kawakami C Sugaya N TakashitaB Fujisaki S Kishida Xu Imai M Tashiro MOdagiri Influenza Virus Surveillance Group of Japan EE se ll NE g lt ul NH 4 25
47. H25 6 27 H25 6 27 H25 6 27 1993 2012 EPEC RFLP intimin EAggEC 24 25 25 25 25 25 25 25 2
48. 013 22 24 1 19 2013 25 43 64 2014 3 25 33 39 2014 3 25 233 238 2014 3 25 60 65 2014 3 25 58 63 2014 5
49. Sakamoto S Kasahara M Saitoh A Akihiko Saitoh Nobuhiko Okabe Yuki Matsushima Etsuko Nakajima Mariko Ishikawa Atsuko Kano Ayako Komane Tsuguto Fujimoto Nozomu Hanaoka Nobuhiko Okabe Hideaki Shimizu Koji Nabae Hiroshi Satoh Hiroshi Nishiura Keiko Tanaka Taya Nobuhiko Okabe Kazunori Oishi Kunichika Matsumoto Tomonori Hasegawa Yahata Y Sugita Konishi YOhnishi T Toyokawa T Nakamura NTaniguchi K Okabe N Nakamura Y SugawaraT Ohkusa Y Taniguchi KMiyazaki C Momoi M Okabe N 5 25 EBS 2009 2013 24 12 21 2
50. lAglCdlImn Sn Sb Tel 1 Xe 3 rmml rlp sglBhlHslMlps sgl mluwl lowpl ip luwsluwe Nel Lr 5 HP MW ICP MS 4 MW ICP MS 4 6 2 5 1 2
51. ss1on analysis SAS Version 9 2 aOR 8 43 95 CI 1 14 62 40 p 0 0369 aOR 40 33 95 CI 2 99 co p 0 0071 aOR 01 95 CE1 12 22 47 p 0 0331 aOR 8 13 95 CI 1 36 48 43 p 0 0215 aOR 10 50 959 CL1 77 62 37 p 0 0097 aOR 7 68 959 CL1 46 40 49 p 0 0162 9
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