90925548-01A
Contents
1.2. 3 5 7 AIR2 Alair
3. Danek CJ et al 2004 Brown RH et al 2005 2 8 18 EN 60601 1 2006 EN 60601 2 2 2009 IEC 60601 2 18 2009
4. lt 2 6 1 3
5. ITT Alair 0 48 0 70 95 CI Alair 0 031 0 520 Alair 26 40 95 CI Alair 2 1 25 1 10 90925548 01A TPBS Alair BT Catherter ME 192 9 Q 0 0 0
6. 1 1 3 N NH 1 1 3
7. 5 mm 4 1 2 6 4 2 4
8. NR 5 9 6 7
9. 3 10 cm d gt
10. 1 2 ICD 14 NSAIDs
11. Alair lt gt lt gt D 2 0 mm 5 3 mm lt gt 90925548 01A TPBS Alair BT Catherter ME 192 4
12. 16 90925548 01A TPBS Alair BT Catherter ME 192 ce
13. 2 7 2 2 3 2 8 _ Alair RS 22600BZX00386000 BA 250 22400BZX00022000 1 1 4 7 6 Q
14. Mayse et al 2007 2 4 FEV1 80 FEV1 80 a
15. 24 ICU 12 i 4 ii 3 4 dO J
16. 90925548 01A TPBS Alair BT Catherter ME 192 2 6 lt 9
17. 3 5 mm 5mm smm 3 2 7 90925548 01A TPBS Alair BT Catherter ME 192
18. 3 5 50 mg Intent to Treat ITT Per Protocol PP ITT 1 PP ITT 6 9 12 1 1 AIR2 Alair
19. 1 dO UD 5 mm
20. Alair 6 377 6 7 EC 7 Alair Alair LIRA 8
21. 2 6 GR 1 1 Danek CJ Lombard CM Dungworth DL Cox PG Miller JD Biggs MJ Keast TM Loomas BE Wizeman WJ Hogg JC Leff AR Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs J Appl Physiol 2004 97 5 1946 53 Brown RH Wizeman W Danek C Mitzner W Effect of bronchial thermoplasty on arway distensibility Eur Respir J 2005 Aug 26 277 82 Mayse ML Laviolette M Rubin AS Lampron N Simoff M Duhamel D Musani Al Yung RC Mehta AC CHnical Pearls for Bronchial Thermoplasty J Bronchol 2007 14 115 23 2 4 10 2 03 6853 0940
22. 1 4 4 W WN lt N 5 mm 5 5 5 mm 4 4
23. 3 50 mg 1 9 1 9 Mayse et al 2007 lt FEV 85 MM Mayse et al 2007 3 SpO 90 48 4 14
24. 95 CI Alair 0 425 6 397 6 95 CI Alair 0 01 0 001 95 CI Alair 0 11 0 83 95 CI Alair 0 025 0 172 Alair 11 Alair 95 CI Alar 4 0 27 3 Alair 3 7 15
25. 2 2 3 2 2 1 31 150mL 5 12 0 133 12 Alair 0 230 12 Alair 0 086 12 0 028 12 Alair 0 062 12 0 075 12 AIR2 Alair 36 Alair 1
26. AIR2 CS 8 LABA Alair Alar 2 1 ICS 1 000 ng LABA 100 ug Alair 3 3 6 12 6 9 12
27. Q lt i 4 10 2 03 6853 1000 Boston Scientific Limited 90925548 01A TPBS Alair BT Catherter ME 192
28. 1 gt Alair gt gt Q 1 SLI KS 1
29. 3 i AIR2 Alair Alair 5 0mL Alair 7 1 3
30. 4 AIR2 4 5 FEV 65 48 12 10 mg
31. 9 K Alair 10 3 6 12 46 ITT Alar 1 3 3 9 6 12 46
32. Alair N 190 96 0 N 98 0 025 0 445 PP 0 244 Alair N 173 97 9 N 95 0 009 0 478 AIR2 Alair Alair 8 6 6 12 NND 288 Alair 3 2 2 Alair 3 AS Alar N 190 N 187 a B EE EC 30 Hi 3 5 5 jn ls EE 5 s 4 2 6 1 s sFwlz AE 3 4 ET 3 1 1 3 Dl lr Oo WWW 2 a
33. 2920925548 01 2014 10 20 1 22600BZX00386000 51 44775003 Alair Alair
34. 3 95 CI Alair 4 6 19 7 Alair mm 11 ITT 6 7 AQLQ 2 6 9 12 AQLQ QOL AP Alair 0 210 95 CI Alair 0 025 0 445 96 4 ITT 96 0 PP 97 9 PP Alair QOL NO AQLQ 1 1 AQLQ AQLQ 95 CI ITT 0 210
35. a 52 39 27 43 5 6 4 3 4 18 1 3 1 1 a I TN MET ME EE ME 9 10 1 2 1 1 Ls se 9 4 s 90925548 01A TPBS Alair BT Catherter ME 192 4 2 2 4 202 5 6 3 5 3 2 3 3 5 6 12 Alair 1 3 Alair 1
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90925548 01A