後半（抄録） - 鹿児島市医師会
Contents
1. 49 W1 3 2 32. HBO
3. 49 14 2 1 2
4. 49 HBO HBO
5. Vol 49 Supplement Sep 2014 7 5 2 9 9 1 2
6. 1996 2013 18 1996 2005 10 2 5 10 10 1 5 524 50 1996 1 5 20 5 400 2 10 900 2
7. 43 44 13 4 1 2 HBO
8. 42 85mm 10 22 25 MSSA
9. HBO Hyperbaric Oxygen Therapy 1989 2014 51 HBO 15 HBO 2 2 0 2 8ATA 60
10. gt gt S2 6 1
11. 26 52 1 1
12. HBO Vol 49 Supplement Sep 2014 14 1 10 10
13. MS MS Scuba diving II MRI MRI
14. HBO W2 2 ICU DIC 7 ICU 36 61 2 20 16 ICU 7 3
15. Vol 49 Supplement Sep 2014 4 4 HBO 1 2 TEVAR TEVAR 2 TEVAR 2 HBO
16. 2 2 20 21 60 61 2
17. HBO DC1 DCI DCI DCI
18. 2013 3 250 mL ATP cytochrome c oxidase 1 mmHg 0 14
19. 73 14 W1 5 1 1 48 1 4 5000
20. HBO HBO S1 1 2 1 2 3 HBO HBO
21. 50 1975 Vol 49 Supplement Sep 2014 1973 J P
22. MRI distributive shock Vol 49 Supplement Sep 2014 5 3 1 1 2 1 2
23. 14 15 5 18 randomized control study 7 8 4 2
24. 1 2 JTS T 7321 JIS T 1001 JIS T 0601 1 JIS T0601 1 1 11 Vol 49 Supplement Sep 2014 Wf1 2
25. 26 35 35 35 TE 351Q 12 table2 5ATA 15 15 15 5ml h 10ml h
26. HBO Wagner grade 2 1 44 glucose439 HbA1c15 0 Wagner grade B 2ATA 60 HBO 12 HBO 3 2 54 Glucose258 HbAlc7 3 Wagner grade 2ATA 60 HBO MRSA
27. 2 1 57 43m 45 10 2 HBO TT6 60ft 9 TT6x4 TT9x2
28. HBO HBO HBO NHC 230 1 2011 2013 10 HBO BARAMO HB SAS BARAMO 60 HBO BARAMO
29. 10 1 HBO 2 HBO 2 2 HBO 2 HBO
30. 1 2 CE
31. 45 46 14 4 1 1 ME ME ME CO 4 5 1 1 Model 2500B 1
32. SD 2 7 3 DCI 1 DCI MRI 12
33. 37 1 31 1 4 DAN 53 6 32 3 36 3 76 7 23 3 80 0 20 1 2 2 20 23 3
34. Vol 49 Supplement Sep 2014 7 1 1 1 2 SD SD SD SD
35. Type T Table 6 Type II
36. 2002 2012 2013
37. QOL 21 22 3 2 0 1 2 4 precapillary vessel
38. 1960 Boerema 1960 1964 1966 1 1969 4
39. 8 ICP HBO ICP HBO ICP ME ME
40. HBO 2 HBO CO HBO 2004 1 2013 12 10 CO 41 20 HBO HBO HBO 10 HBO 89 55 2009 HBO 21
41. B Vol 49 Supplement Sep 2014 W1 6 HBOT NM 1 2 HBOT PM ICD HBOT 26 169 26 7 21 1 web 7
42. Vol 49 Supplement Sep 2014 S2 4 2004 Undersea and Hyperbaric Medical Society UHMS mild Himb pain constitutional symptoms some cutaneous changes rash mild 1
43. 8S2 2 100 DC1 DCI DCI 3 3 DCI DCI
44. HBO Undersea and Hyperbaric Medical Society UHMS European Committee for Hyperbaric Society ECHM UHMS Comparative study approved indication HBO 2014 13 14 approved indication ECHM 6 3 StagelV ECHM UHMS 1986 HBO
45. MRI DCI DCI DCI Vol 49 Supplement Sep 2014 6 1 1 3 2 1 5 1 3 1
46. 1971 100m 1972
47. Comp WCU Comp WCU WCU WCU 2
48. HBO HBO 74 H25 12 20 12 23 24 27 HBO HBO 2ATA 100 2
49. 1 3 196 560 29 1 3 Cochran Mantel Haenszel OR OR 3 OR 6 52 3 OR 1 43 3 OR 0 12 3 OR 0 53 3 OR 0 17 3 OR 0 75
50. ME HBO Kohshi 1991 HBO HBO HBO Ravenna
51. 1 Vol 49 Supplement Sep 2014
52. 1 2 3 2D DIGE 2 Dimsendional Fluorescence Differential Gel Electrophoresis LC MS MS 32 4kDa transthyretin TTR 44 8kDa ze 1 aeid glycoproteim TTR TTR 8 14 4 10 6 3 EL
53. 1 5 HBO HBO HBO 1 ME Vol 49 Supplement Sep 2014 S1 2 2
54. 19 641 635 6 1984 1 10 4 1 2 KHO 2000 KHO 2000S 200 3 1 16 2 1 2 2
55. 2005 4 2013 3 9 160 11 53 44 21 5 19 7 1 2 2 1 1 618 6 5 6 1 3 7 309 10
56. HBOT CT HBOT 2013 1 2014 6 HBOT 98 HBOT CT 30 HBOT 24 6 1 CT CT 3D HBOT CT 2 2 HBOT HBOT 1 10 41 7 6 100 p 0 013 HBOT CT
57. 1 5 2 3 97 81 7 9 WEB
58. 1988 Goldberg Hep3B HIF 1 HIF 1z HIF 1z
59. 1 SD Wilcoxon p lt 0 05 p lt 0 01 6 33 2 4 8 BMI25 8 0 9 15 35 3 756 0 153ata 124 7 56 62 1 1 16 45 7 I 14 TI 2 IV VAS n 16 53 25 11 14mm n 19 40 88 10 28mm p lt 0 05 HHV 6 113 26 55 21 75 26 66 45 p lt 0 01
60. B 1
61. 1 2 3 HBO HBO SPECT CT
62. 49 MAGNETIC RESONANCE IMAGING OF CENTRAL NERVOUS SYSTEM DECOMPRESSION SICKNESS IN SHEEP UNDERGOING HYPERBARIC EXPOSURE Sobakin AST Hutchinson E Lehner CE Eldridge MW Diving Physiology Laboratory and the Departments of Pediatrics and Biomedical Engineering University of Wisconsin School of Medicine and Public Health Madison WI 53792 BACKGROUND We have previously demonstrated that oxygen pre breathing before drop out decompression reduces the risk of decompression sickness DCS in the UW sheep model However little is known about the incidence and mechanisms of neurological injury in these models or the effects of decompression strategies on ameliorating neurological DCS We have undertaken magnetic resonance imaging MRI studies to define the incidence and mechanism of CNS injury in a sheep model of decompression sickness MATERIALS AND METHODS Ten adult ewes 91 4 9 2 SD kg underwent dry chamber air exposure at 60 fsw 2 8 atm abs for 24 hours followed by an oxygen 88 92 pre breathe for 3 hr before dropout decompression at 30 feet min 0 9 atm min to surface Another four animals 95 6 5 8 SD kg underwent an identical decompression scenario withou
63. 8 2 26 27 Vol 49 Supplement Sep 2014 1 CLI 2
64. HBO 51 6 45 6 HBO 30 1 43 HBO 20 3 40 1 34 0 HBO HBO Vol 49 Supplement Sep 2014 12 1 27Ga citrate SPECT CT
65. HBOT HBOT 2 1 1 4 HBOT SAP HBOT SAP SAP HBOT Vol 49 Supplement Sep 2014 11 1 Fournier 1 2 1 2 DM 46
66. 2 6 8 1 2
67. 1 5 HBO HBO HBO 9 251 HBO 10 4 grade HBO 11 3
68. 2 60 15 CRP 11 4 3 2X10 1 5 0 1 2X10 7 1 CRP 16 1 6 5mg dl 0 7 0 7mg d1 1
69. 9 1 5 Compromised host HBO 2001 2013 HBO 7484 411 5 5 68 16 5 HBO HBO 41 0 HBO 8 9 49 8 15 7 63 0 20 0
70. Web 49 W1 4 1 24 11 16 2 2
71. 5 1 49 5 4 1 2 HBO 2001 2 1 2002 1 1 2014 9 1 2 11 666 1 6 053
72. 5 10 CT 5 Fournier 13 52
73. SAP 2 SAP HBOT 1 SAP HBOT 2013 6 2014 9 SAP 12 8 4 HBOT 2ATA 60 15 12 HBOT 7 8 4 57 4 1 9 SAP HBOT
74. ECMO Extracorporeal membrane oxygenation 49 S1 3 CO HBOT CO HBOT HBOT CO HBOT CO CO CO CO 250
75. 2 USNTT6 DCI DCI 2 4ATA HBO DCI HBO NBO HBO NBO 2 8ATA 60 90 HBO HBO USNTT6 HBO USNTT6 DCI HBO USNTT6
76. ME OT Ct CO 7 8 2002 HBO HBO 2002 1 2014 7 HBO PTA CABG MDT VAC HBO HBO 2 PGE1
77. 1 HBO 26 7 20 3 19 8 4 3 1 12 2 6 1 2 4 36 67 32 311 103 4 79 24 4 HBO 4 33 1 4 1 4 23 16 7 6 10 7 4 36 20 56 HBO 19 1 HBO 10 9 15 4
78. HBO 90 3 121 134 HBO DDS b FGF 1 2 3 9 QOL HBO 49 2 HBO
79. PCPS ECMO DCI USNTT5 amp 6 DCI Ir 28 5 6 3 lt 2 3 1 2 3 DCT DCI DCI 3 1 40
80. 2 0ATA 90 1 HBOT 23 JCS 300 JCSI 30 30 50 100 7 CPK COHb MRI CO 100 HDS R19 30 Vol 49 Supplement Sep 2014 1 2
81. 1 2 HBO 1 HBO I 1 HBO 2 HBO 2 HBO 77 7 W1 1 1 2
82. 49 9 2 2 1 ME 25 4 HBO Tissue Oxygenation Index TOI HBO HBO TOI NIRO 200NX Hb Hb Hb
83. ME 2007 2010 2 2013 3 IMRT 2012 16137 1345 72 1 HBO 38 10 4
84. CT 48 HBO 2 0 60 1 1 HBO 5 5 HBO 59 2 50 CT CT 23 3 HBO HBO
85. 2591 11 SE mm3 HBO 2542 8mm 6 4051 21mm3 3820 21mm HBO 2 24 3588 13mm 3310 13mm HBO p 0 002 3 2775 13mm 2459 28mm3 3 HBO 0 04 5 2468 16mm3 2314 10mm3 7 2469 10mm3 2366 12mm3 2 HBO 6 peak Peak 2 5 HBO 3 HBO
86. Vol 49 Supplement Sep 2014 13 1 1 2 4 37 6 100 2 1 3 3 30m
87. HI 54 20m 2 I CT HBO Table 6 CT 3 MRI T2 21 23 13 HBO
88. 12 collagen non collagenouse protein Elastin HBO Fibrosis Vol 49 Supplement Sep 2014 3 3 1 ME 2 HBO 2006 1 2014 5 34
89. 6 TV 500ml 2 15 30L min FIO FIO TV CO TTL CO0 FTIO 15L min 30L min 0 64 0 70 0 69 0 76 0 74 0 78 NPPV 0 66 0 73 0 58 0 62 0 92 0 96 FTO FIO2 65 30L min 2 5ATA
90. HBO PAD critical limb ischemia CLI 2002 4 2 HBO DDS b FGF 2007
91. HBO 1 3 HBO 14 3 1 2 1984 2013 4 361 37 649
92. HBO 49 4 5 HBO 2 1 5 HBO HBO 24 54 30 24 21 73 40 HBO 30 2 0ATA 60
93. CO 1 64 7 37 0 13600 mu CRP 33 1 mg dl 731 mm3 173 mg dl 4 g C1 2 T2
94. DCI MRI 12 54 9 5 1 4 DCI MRI 11 9 4 4 1 2 27 32 7 4 D
95. 84 elephant trunk TEVAR 7 MRI HBO 2ATA 60 7 MMT 2 4 85 Stanford B DIC entry TEVAR 3 HBO 2ATA 60 4 MMT 1 3 9 Stanford A TEVAR HBO
96. HBO HBO HBO HBO MRSA MRSA HBO MRSA HBO
97. 2 1 2 4 HBO CT HBO 10 Wister 20 10mm 640g 25cm CT 15mm HBO 2 5ATA 2 table 30 1 1 5 HBO 20 HBO 20 6 24 3 5 7
98. Ga citrate Target to Background Ratio TBR HBO1 TBR 70 2011 11 4 2012 5 Ga citrate SPECT CT 4 TBR 8 16 HBO1 2 8 1 1 20 1 Ga citrate SPECT CT TBR 6 74 1 2 HBO 1 jG
99. 67 33 HBO 95 HBO 2 49 10 2 CT 1 CO 4 5 HBOT
100. 1 2 STA MCA bypass 3 HBO 8 2 2ATA 90 HBO 43 10
101. HBO 20 30 HBO HBO 700 3 HB 0 12 3 1 AS bl
102. 1 Negative Pressure Wound Therapy NPWT NPWT Vol 49 Supplement Sep 2014
103. HBO HBO 49 W2 5 HBO 1996 2014 50 7 6 8 3 jinstrumentation 4
104. 2 HBO 1 4 HBO 21 2 0 silo 26 silo HBO HBO 7 46
105. 2 34 1 2 1 HBO TT6 29 20 6 4
106. HBO 9 3 HBO 2 1 ME 2 HBO tcpO2 HBO tepO2 2 0ATA 2 5ATA tcp02 tcp02 2
107. 2 4
108. 3 4 HBOT HBOT 16 2009 4 2014 5 HBOT 6 10 70 16 HBOT HBOT Model 2800J 1 1 2 60 HBOT CRF WBC t HBOT CRP p 0 591 WEBC p 0 034 HBOT
109. NBOT NBOT HBOT CK HBOT S1 4 2 1 b hyperbaric oxygenation HBO HBO
110. 1 68 7 58 3 95 2 2 3 HBO HBO HBO
111. 4 49 30 19 3 4 14 1 4 HBO 48 38 48
112. 5 3 2 30 4 2 0ATA 2 5ATA 2 0ATA 10 15 20L min 2 5ATA 15 20 30L min TCM400 tcp02 Inspiron 2 0ATA 10L min 15L min 20L min tcpO2 389 1mmHz 448 6mmHg 531 5mmHlg 2 5ATA 15L min 20L mn 30L min tcp02 529 2mmHg 653 7mmHg 705 1mmHg tcp02 2 0ATA 20L min 2 5ATA 15L min tcpO2 2 5ATA
113. HBO 2 1 1 HBO ADL DIV TInstrumentation PLIF instrumentation HBO HBO HBO HBO
114. HBO 84 12 AUA score Nakada Lovenberg HBO QO HBO collagen non collagenouse protein elastin 2 109 12 HBO non collagenouse proterm El astin Weiss HBO 5 Del Pizzo 2 HBO collagen non collagenouse protein
115. 0 1MPa 0 1MPa 15 HBOT 5 5 5 HBOT 2013 10 2014 4 84 HBOT 12
116. 10 4 2004 2013 10 2004 39 2013 220 10 8 2004 23 CRAO4 2 CO 1 1 1 7 2013 124 31 17 9 CO 8 CRAO8 7 7 11 2004 24 7 3 2 2 1 2013 108 32 14 14 13 12 8 7 5 5 2
117. HBO 1 2 80 24 12 1 2 HBO MRI T2 1 6 79 HBO 2 0ATA 60min HBO MMSE HDS R
118. 25 5 8 20 2 1 1 1 64 3 WBC 1 7916 1 CRP 29 2 mg dl 17 DM 2 5 HBO 10 1 45 HBO 10 40 3 1 22 8 14 2 HBO CRP HBO 2 HBO
119. 4 2004 340 200 2002 35 2013 39 2013 16 8 3 299 59 7 2010 60 6 3 2 1
120. VAS HHV 6 HHV 6 IL 6 Mclellan 60 HHV 6 25 26 5 2 HI 1
121. 10 15 3 3 MSSA 60 20
122. 9 1 6 6 40 6 14 0 HBO HBO HBO HBO 49 4 1 1 1
123. 2011 4 2014 3 3 136 97 71 3 39 28 7 65 5 31 21 101 74 3 48 5 25 0 24 3 18 4 15 4 14 7 65 58 8 75 30 1 74 3 11 2 25 0
124. 2012 121 92 48 86 mild UHMS 47 39 23 65 37 7 26 962 169 US Navy table 6 1 8 1 5 58 1 38 4 3 5 mild 12 74 74 39 mild mild 13 5 p 0 085 219 mild 1 lt 0 05 83 3 8 3 86 3
125. 75 4 5 7 HBO 2009 3 2 8ATA 2009 4 2 5ATA 1 Visual Analog Scale HBO HBO HBO 43 9 42 3 4 250 57 9 6 7Gy 48 3 32 5 32 HBO 20 12 12 11 2
126. Vol 49 Supplement Sep 2014 2 3 2 9 A 1 ME 2 3 FIO2 FIO FIO2 TTL 2 1 2 NPPV
127. 12 3 2014 5 2014 9 51 HBOT 4 HBOT 13 3 24 592 9 4 5 Type II
128. 5 6 50 180 1 91 50 3 36 6 20 65 61 31
129. 500 600 25 HBO 3 HBO 309 51 17 2 8 2 Table 6 HBO 1 13 HBO
130. OR 0 53 OR 0 36 OR 10 64 OR 1 66 OR 2 63 1 3 49 6 2 18 1 2 3
131. 1 RJ 3200 50ml X1 L150 18G 5ml h 10ml h 0 3 0 3 13 2 8 2 6 0 2 2 11 6 7 3 4 3 2 2 2 5 1 0 5ml h 45 1
132. 10 HBO 64 STA MCA bypass CRP 10 HBO 39 STA MCA bypass 10 HBO STA HBO 49 1 3
133. WCU Comp 2 7 20 2 2 1 ME 2
134. SPECT CT HBO 8 HBO HBO 2 P 1000 PGE1 10 g 2 8ATA 2002 1 2011 7 HBO 230 2006 54 3 125 230 SLE HBO 5
135. 3 1 80 60 HBO 26 2 1 HBO HBO 2ATA 1 HBO 40 11 4
136. P SAS HBO SAS BARAMO Stephane Garrigue M D Philippe Bordier M D Pierre Jais M D et al Benefit of Atrial Pacing in Sleep Apnea Syndrome N Engl J Med 2002 346 404 12 Vol 49 Supplement Sep 2014 10 1 2 HBO 1 HBO 2 1 70 41
137. 452 2 2001 HBO 1 1 900 HBO 1 3 8 HBO 2013 939 220 719 71 2014 4 1 1 2
138. 25 2 PCPS ICU 7 9 1 Clostridium 2 3 37 1 ICU 1 ICU 1 ICU ICU ICU 15 76 W2 3 2 1
139. HBO HBO 7 18 1 1 CO 1 2 9 1 2 3 CO 1 HBOT 20 JCS 300 CPKMAX2114 U 1 COHbMAX32 0 HBOT 2 8ATA 100 2 5ATA 90 1 HBOT 3
140. 10 2013 ON HBO 5 5 9 1 2 3 DCI USNTT 1 USNTT5
141. 65 6 400 FM 800 SD 24 SD SD 40 2 SD 105 89 75 157 55 43 SD 88 SD 233 mmHg 109 107 61 SD SD 198 92 147 86 120 72 96 100 80
142. SD SD SD 100 49 7 2 2 1 2 SD SD 2
143. 0msw Dry 440msw Dry 443msw Wet 0msw Dry 3m Wet 443msw Wet 3msw Wet 443msw 440msw 8 2
144. 10 69169 40 8 82 26 PM ICD HBOT 15 75 10 29 43 7 43 21 90 55 18 3 25 13 8 71 20 9 HBOT PM ICD 29 64 7 HBOT PM ICD 2 4 87 4 4 25 50 25 0 7 6 PM ICD
145. 66 10 19 CPA50mg day 25 5 3 11 10 12 24 HBO RBC234 nl Hb7 4g dl Hb 4 0 5 0 8 HBO 3 HBO 50 Hb 10 0 12 0 2 25 4 5 90 HBO CPA HBO CPA
146. HIF l1a Hypoxic microenvironment HIF 1z HIF 1 ATP Warburg
147. NHC 410A 4 2 5ATA 0 5 ATA HAMILTON C 1 LTV 1000 Trilogy 0 MONNAL T60 Bennet RM121 SIMV 12 PEEP4 cmHg FIO 0 21 1 0 PEEP PEEP FIO LTV 3 ATA LTV 1 5ATA 4 ATA T60
148. 61 9 6 5 ICU 9 25 3 ICU 33 19 8 A B 1 3 Clostridium 2 5 50 11 6 42 19 19 14 15 9 60 5 3 CHDF PCPS
149. W2 4 HBO HBO HBO 2008 6 1 2014 5 31 4252 SIRS systemic inflammatory response syndrome HBO 434 10 2
150. tcpO2 tcpO02 35 36 9 4 BARAMO 1 2 HBO 1 HBO SAS SAS
151. 10 48 10 20 26 20 26 5 6 2 4 15 1 13 2 1 3 1 700 2 000 14 49 8 1 443msw
152. HBO Vol 49 Supplement Sep 2014 9 1 HBO tcpO 3 4 A D A B D C D C D TCM400 6 3
153. 22 10 6 2 1 HBOT 10 6 HBOT HBOT HBOT 41 42 12 4
154. Fournier Fournier Fournier Fournier 49 11 2 2 1 2
155. HBO 3 24 4 3 2 5 2 2011 2014 11 9 1 1 8 3 1 46 90 71 5 6 5
156. HBOT 21 HBOT 20 7 63
157. 55 59 15L min tcpO 23 5C 65 tcpO 6 A 3 74 B 4 28 C 4 28 D 4 29 B D tcpO B D tcpO HBO
158. CO HBO 49 S2 1
159. HBOT 1 49 W2 1 lt 7
160. p 0 008 mL 609 113 418 47 575 116 834 220 0 038 mLL 192 96 259 246 2 30 0 578 700mL p 0 040 HBOT HBOT HBOT HBOT 700mL HBOT 700mL 10 3
161. p 0 057 219 mild mild mild UHMS 49 S2 5 gt gt 7 26 8 815 gt
162. 1 DCI DCI 60ft DCI DOI 70 S2 3 II pitfall II
163. 10 40 8 49 13 2 9 1 2 3 HBOT
164. 6 13 1 HBO 14 6 HBO 15 4 1 9 11 HBO HBO 5 1 VAS Visual Analogue Scale HHV Human Herpes Virus 6
165. 48 S1 1 1 HBO Consensus HBO operation 1 2010
166. 20m 1 DCI 1 CT 2 40 3 DCI CT 3 50 20 25 m 30 5 6 1 2 DCI
167. 3 ATA T60 HBO 3 1 1 HBO 23 HBO CPA HBO 1
168. 70 N0301 65 10302 2 50 40 FM 800 ZERO 40 2 24 SD 4 2 SD SD SD SD SD
169. 1 433Torr 2 8ATA 2 8ATA 25 0 49 2 4 HBO HBO HBO HBO 2
170. 2 2 150msw 443msw 5 440msw 443msw Wet 440msw Dry 0msw Dry 3msw Wet 24
171. 90 150 mmHg 20 9 150 150 carotid body
172. H 1 2 MM 4 47 610 48
173. 2 3 ME
174. Hb Hb Hb HBOT Hb CO CO HBOT HBOT CO HBOT CO HBOT HBOT
175. ICU HBO HBO S1 5 2 7 1 2
176. RCPM FAB HBO MRI MMSE 19 27 HDS R 20 27 RCPM 18 28 FAB 5 16 HBO HBO 7 2 1 1 ME WCU Comp 9 1
177. TOI TOI Hb Hb 10 68 3 HBO 2ATA 60 HBO BARA MED ETC HBO TOI HBO TOI HBO TOI HBO TOI HBO TOI X100 TOI HBO p lt 0 01 4 560 TOI HBO lt 0 01 3 42 HBO TOI HBO
178. 10 g 2 8ATA 334 60 8 203 334 HBO 5 Fontaine IV 9 93 2 178 191 VAC 1 2 3 HBO VAC QOL Vol 49 Supplement Sep 2014 S1 6 HBO
179. AN 16 2 1 NPO 2 DAN 1976 1996 DAN 1998 DAN 16
180. ISA TTR mRNA PCR LightCycler 480 10 TTR ELISA TTR 420 0zg mL 545 2 g mL PCR TTR TTR TTR 3 34 8 3
181. a citrate SPECT CT HBO 49 12 2 HBO
182. t oxygen Dre breathing Six weeks after exposure animals were sacrificed and brain and spinal cords are fixed in formalin T2 weighted fast spin echo imaging and high resolution 3 dimensional spin echo imaging were performed on the spinal cords using a high field strength Varian 4 0 Tesla MRI scanner RESULTS Decompression without oxygen pre breathing resulted in 100 mortality All the oxygen pre breathing animals survived Six animals developed limb bends with one developing signs of respiratory DCS Thus far we have found no evidence of focal infarcts in the spinal cords of the oxygen pre breath group However patchy areas of increased T2 signal intensity are seen in white matter CONCLUSION Thus far we see no evidence of discreet spinal cord infarction as would occur with arterial gas embolism suggesting that 3 hr oxygen pre breathing may reduce the severity of neurological DCS However subtle areas of increased signal intensity may represent white matter injury Our ongoing work will use high resolution diffusion tensor MRI to further characterize the possible white matter injury 1
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