Home

HCSO User Guide.book

1. Click the dropdown list and select the specific substance from the list Display Comparison When all drugs you wish to compare have been searched and matched click the Display Comparison button Two drugs will be displayed side by side on the Document Comparison page 2009 Thomson Reuters All rights reserved DRUG INFORMATION Drug Comparison Modify Your Search Display in Column One C Display in Column Two Display AMOXICILLIN see details in DRUGDEX Dosing amp Indications Adult Dosing see details in DRUGDEX Back to top Bacterial endocarditis Prophylaxis 2 g ORALLY 1 hr prior to procedure Chlamydial infection pregnant women 500 mg ORALLY 3 times a day for 7 days Ear nose and throat infection mild to moderate infection 500 mg ORALLY every 12 h or 250 mg ORALLY every 8 h Ear nose and throat infection severe infection 875 mg ORALLY every 12h or 500 mg ORALLY every 8 h Gonorrhea acute uncomplicated anogenital and urethral infections due to N gonorrhoeae 3 g ORALLY as a single dose amoxicillin is NOT the drug of choice for gonorrhea because of resistance Helicobacter pylori gastrointestinal tract infection 1 g ORALLY twice a day in combination with clarithromycin 500 mg ORALLY twice a day and lansoprazole 30 mg ORALLY twice a day for 14 days or amoxicillin 1 g Adult Dosing see details in DRUGDEX CEPHALEXIN see details in DRUGDEX Dosing amp Indicati
2. Background Definition Epidemiology Etiology Pathophysiology Complications History and Physical Summary Medical History Findings Diagnostic Testing Diagnostic Testing Summary Incidence Tests Diagnosis DVT affects approximately 100 persons per 100 000 in the western world LL In the USA it Differential Diagnosis affects about 2 million annually 21 It is the third most common cardiovascular disease Treatment behind acute coronary syndromes and stroke l Treatment Summary Deep venous thrombosis Acute Background Definition A portion of the venous thromboembolism disease process in which blood clots form deep in the veins Epidemiology Print Ready Select the Print Ready button or link when you wish to print the document in its entirety minus the outline navigation buttons and links The Print Ready option opens a new browser window with the document shown as a print preview Print by selecting the print option from your Internet browser menu Print Setup Select Print Setup when you want to print portions of the document The Print Setup link presents you with a selection page to allow you to choose which sections to include in the printout of the document For more print options and information on printing documents see Printing Documents on page 30 2009 Thomson Reuters All rights reserved DISEASE INFORMATION CheckAll Uncheck All C Background C Def
3. Type the Allergy in the search field Select the Allergy and click the Add Button Click on Add Allergies when you are done to add to the Drugs to Check list for drug interactions Enter Allergy penicillin Matching Allergies 9 Allergies To Add PENICILLIN G PENICILLIN G PROCAINE PENICILLIN Y PENICILLIN AMINOPENICILLIN PENICILLIN EXTENDED SPECTRUM PENICILLIN NATURAL PENICILLIN PENICILLINASE RESISTANT PENICILLIN PENICILLINASE RESISTANT Add Allergies Click the drug in the Matching Allergies list then click the add button to add it to the Allergies to Add list Repeat until all allergies have been added to the Allergies to Add list then click the Add Allergies button to close the dialog box Notice that the allergies entered appear with asterisks in the Drugs to Check list in capital letters This clearly separates the drugs to check against the drug allergies 5 When all drugs and allergies have been entered click the Check Interactions button Interactions Search Results Interaction information is displayed on the Drug Interactions Results page 0 ec Drug Interactions Results BPrintReady History lt Modify Your Search Jump To Drug Drug 1 Ingredient Duplication 1 Drug Allergy 0 Drug Food 1 Drug Ethanol 0 Drug Lab 2 Drug Tobacco 0 Drug Pregnancy 4 Drug Lactation 4 Drug Drug Interactions 1 R
4. Some Drug Consults present patient related referenced consultations with case histories They are also an excellent resource for information on herbal medications medical and surgical materials excipients drugs of abuse and health foods Drug Consults are provided for investigational international FDA approved and over the counter preparations DRUGDEX Product Index Product documents offer comprehensive search results listing trade names manufacturers and dosage forms for investigational international FDA approved and over the counter preparations DrugPoints System The DrugPoints System provides brief highlights of dosing drug interactions adverse effects pregnancy warnings indications cautions therapeutic class and brand information The DrugPoints System delivers answers quickly and efficiently The System also links directly to more in depth DRUGDEX Drug Evaluations available only with a current DRUGDEX subscription 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS DRUG REAX System Interactive Drug Interactions The DRUG REAX System allows clinicians to check for interacting drug ingredients their effects and their clinical significance It provides drug drug food drug drug disease drug alternative medicine drug ethanol drug laboratory drug tobacco drug pregnancy and drug lactation interactions Please note that not all additive adverse effects or therapeutic antagonis
5. ns Normal saline Sodium Compatible results chloride 0 996 112 NS Sodium chloride 0 45 Click a link to view detailed compatibility Not Tested Key Compatible A Caution Variable Incompatible Uncertain i Not Tested Summarized or high level results of the drug compatibility are shown on the compatibility overview page The Solution results page opens first by default To view a different result type Y Site Admixture Syringe or TPN TNA click the tab link name for the desired type Compatibility is denoted by an icon and simple description The full descriptions follow Icon Compatibility Full Description Compatible All studies showed these items as compatible A Caution Variable Study results vary details need to be evaluated D Incompatible All studies showed these items as incompatible or uncertain Q Uncertain Study results were inconclusive compatibility wasn t determined a Not Tested No study results were found Overview Page Navigation The Search Path or Breadcrumb The search path also known as a breadcrumb displays previous pages as links On the overview page it is displayed as Search Path IV Single Compatibility gt Clicking the IV Single Compatibility link takes you back one page to the Single Drug search page 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Start a New Search To search for compatibilit
6. the product name or the synonym The phrase can occur in any order to be considered a match 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION Imprint Code Searches for imprint codes to help identify tablets caplets or capsules by their physical characteristics Search Imprint Codes 1 Type the full imprint code maintaining spaces e g MRK 951 or a partial code e g 951 or MRK in the Search field Tip If the imprint is a picture or a shape such as a triangle star etc you can type a description of the shape as a search term If the imprint is a logo type the word logo as the search term You can search on as few as one alphanumeric characters however performance may be affected when retrieving extremely large result sets 2 Click the Imprint Code button For information on Imprint Code search results see Imprint Code Search Results on page 73 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Active Ingredient and Codes Searches by a specific active ingredient in the substance such as latex or fluorinated hydrocarbons or acetaminophen etc or by a specific code such as NDC CAS or DIN code Searchable Codes NDC codes National Drug Code The standard code format is 5 digits 4 digits 2 digits all separated by a dash such as 00220 9313 04 This search is very much like the contains search therefore searching on
7. ABCIXIMAB ALTEPLASE RECOMBINANT ASPIRIN TEN BIVALIRUDIN CAPTOPRIL EPTIFIBATIDE LISINOPRIL NITROGLYCERIN RAMIPRIL PI SIMVASTATIN STREPTOKINASE TENECTEPLASE VALSARTAN Toxicology NITROGLYCERIN SALICYLATES Studies and Alerts References 1 Antman EM Anbe DT Armstrong PW et al ACC AHA guidelines for the management of patients with ST elevation myocardial infarction a report of the American College of CardiologyiAmerican Heart Association Task Force on Practice Guidelines Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction Circulation 2004 110 9 e82 e292 PubMed Abstract hittowww ncbinim nih qov PubMed Article httouAwww nebinin nih gow 2 Braunwald E Antman EM Beasley JW et al ACC AHA guideline update for the management of patients with unstable angina and non ST segment myocardial infarction a report of the American College of Cardiology American Heart Association Task Force on Practice Guidelines Committee on the Management of Patients with Unstable Angina J Am Coll Cardiol 2002 40 7 1366 74 3 Cheitlin MD ACC AHA ASE 2003 Guideline Update for the Clinical Application of Echocardiography American College of Cardiology Foundation and the American Heart Association Inc Dallas TXAvailable from URL vw m 9 4 Klocke FJ ACC AHAJASNC Guidelines for the Clinical Use of Cardiac Radionuclide Imaging American College of Cardiolo
8. Adverse Reactions Drug Interactions Search Results Document titles are displayed as hypertext links Clicking a title link opens the document at the top beginning of the document 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Below the document title document sections topics where matches to the search terms were found are shown as links Clicking the section name link opens the document directly at the chosen section topic A snapshot or sentence where the search term was found is included to give you an idea of the context Search Path Drug Topic Search gt Search Results Your Search buproprion BUPROPION rug Interactions 2 CITALOPRAM occurred 3 CLOZAPINE occurred 4 NORTRIPTYLINE Document Title Section Topic Drug Interactions risperidone 3 mg day and buproprion 300 mg day Improvement in positive and negative symptoms Showing Results 1 through 4 of 4 levels were 98 ng mL Buproprion SR 100 mg day was reinitiated and ten days later Drug Interactions risperidone 3 mg day and buproprion 300 mg day Improvement in positive and negative symptoms Drug Interactions levels were 98 ng mL Buproprion SR 100 mg day was reinitiated and ten days later Go directly to the Drug Interactions section in the document by clicking the link BUPROPION back to top Expand All Collapse A
9. All rights reserved MICROMEDEX HEALTHCARE SERIES Norepinephrine Levophed Dosing Calculators Adult and Pediatric The adult calculator displays recommendations based on initial dosing and the solution concentration The pediatric calculator also factors in the weight kg Lb of the pediatric patient Drug Classifications Select a Drug Classification tool and click the Go button to view or print the information Results can be viewed or printed See Printing Documents on page 30 for more information 4 Antiarrhythmic Drug Classification Cephalosporin Generations Chemotherapy Acronyms A C Chemotherapy Acronyms D Z Prostaglandin Synonyms NSAID Classification Antiarrhythmic Drug Classification Three tables that break down the name of the Antiarrhythmic and the classification of that drug Cephalosporin Generations Shows the name of the Cephalosporin and the associated generation Chemotherapy A C and D Z Displays acronyms of chemotherapeutic medications Shows the agent and dosages that make up the drug what it is used for and what type of cancer it is used for Prostiglandin Synonyms Lists the name of the Prostiglandin and the associated synonym NSAID Classifications Lists the classification such as acetic acids enolic acids COX 2 inhibitors and the drugs associated with that classification Drug Comparisons Select a Drug Comparisons tool and click the Go button to view or print
10. Aspalathus contaminata Borbonia pinfolia Kaffree tea Psoralea linearis Red bush and Rooibos tea Viewing Documents If the desired substance or condition is listed on the Narrow Results page click the link to open the document All search results lists and documents can be viewed or printed See Printing Documents on page 30 for more information Refining Your Search If you complete a search and the search results return items that do not apply to the information you desire you can quickly return to the alternative medicine search page by either clicking the breadcrumb link or clicking the Patient Education tab and selecting the AltCareDex Alternative Medicine Education menu item Search by Category To search for documents by general condition category click the Category List link Select a category by clicking the link to reveal the documents available for that category 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Search Path AltCareDex Alternative Medicine Education gt Categories Complementary amp Alternative Medicine Categories CARDIOLOGY DENTAL HEALTH DERMATOLOGY DIETARY ee N EAR NOSE THROAT ENDOCRINOLOGY ENVIRONMENTAL GASTROENTEROLOGY GERONTOLOGY INFECTIOUS DISEASES MENTAL HEALTH I MODALITIES THERAPIES Complementary and Alternative Medicine DERMATOLOGY NEUROLOGY E ee OB GYN Titles 8 results ONCOLOGY OPHTHALMOLOGY ORTHOPEDICS
11. Complications Key References Special Circumstances Literature Cited When to Consult or Refer Tables and Images DRUGDEX System Drug amp Pharmaceutical Information Designed to deliver unbiased drug information for those who prescribe order dispense or administer medications the DRUGDEX System provides independently reviewed data gathered from major drug centers and pharmacology services worldwide FDA approved and investigational drugs along with over the counter and non U S preparations are covered with regard to dosage pharmacokinetics cautions interactions clinical applications and comparative drug efficacy Information is reviewed by the Thomson Reuters editorial board and can be retrieved by generic name manufacturer brand name or indications What s in DRUGDEX 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES DRUGDEX includes the following modules e Drug Evaluations e Drug Consults e Product Index Drug Evaluations Drug evaluation monographs appear in a standardized format that allows you to easily find the information you need Specific topic areas include the following e Dosage e Pharmacokinetics e Interactions e Cautions e Interactions e Adverse side effects e Contraindications precautions e Comparative drug efficacy e Clinical applications e Comparative drug efficacy e Indications e Therapeutic uses e Generic names e Indications e Adverse side effects Drug Consults
12. Find all keywords that et Match End in an asterisk diab aceta for Begin With search Begin With Select Databases ON Note Any change you make to the Exactly Match or Begin With search parameter is Z maintained for the duration of your Micromedex Healthcare Series session A session is A7 active until you 1 Logout and 2 Close the browser window Begin With Shortcut You can perform a Begin With search even if the Exactly Match parameter is selected by using an asterisk at the end of the search term Example epil Search Summary Documents Click the Search summary documents only checkbox when you need brief high level information The application will search your keyword against the summary databases e DRUGDEX Drug Summary Information provides brief highlights of dosing drug interactions adverse effects pregnancy warnings indications cautions therapeutic class and brand information e POISINDEX Toxicologic Management Summary Information provides brief highlights of clinical effect treatment and range of toxicity information DISEASEDEX General Medicine Summary Information and DISEASEDEX Emergency Medicine Summary Information provide brief highlights of treatment diagnosis and key point information Clinical Checklist documents Concise compilations of patient care interventions that should always or never be instituted in certain cl
13. Form Tablet Route Oral route Drug Image View or print the drug identification See Printing Documents on page 30 for more information 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES SPECIFIC DATABASE SEARCH When you know that the answer you are looking for is in a specific drug database you can refine your search by using the Specific Database Search option The Specific Database Search page lists the databases available for inclusion exclusion in your search for drug information All databases are selected by default Uncheck the databases you do not wish to include in your search Quickly de select uncheck all databases by clicking the Uncheck All link For an overview of each of the databases click the i information icon i to pop up a database definition Create a Specific Drug Database Search e Type the complete drug name Select the database s you wish to perform this search against e Click the Search button Exactly Match versus Begin With The default search method Find all keywords that Begin With uses the search term as the root term and expands on it You may also be familiar with the term wildcard search The Begin With search acts like a wildcard search with the expansion to the right of the search term You can override the default search method if you don t find the results you expect when performing an Begin With search N
14. Identify a Tablet Caplet or Capsule Imprint Code Description Colors v Other E CTRL click to Black select more ac Sree eee than one color Blue Pattern Al Patterns jj Brown v IDENTIDEX System search Imprint Code only Search Clear If you have typed the wrong information and wish to begin again click the Clear button to remove all codes and characteristics and start over If multiple drugs match the characteristics searched you will see a list of the drugs which matched your search criteria Search Path Drug Identification gt Drug Identification Results Search Results Methocarbamol M 19 LL 00005 3562 23 Methocarbamol M19 LL 00005 3562 31 Methotrexate Sodium M 1 LL 00005 4507 23 Methyldopa M22 LL 00005 3850 34 Methyldopa M23 LL 00005 3851 34 Myambutol M6 LL 00005 5015 23 Myambutol M6 LL 51479 0046 01 Click a link to view the drug information 2009 Thomson Reuters All rights reserved DRUG INFORMATION Search Path Drug Identification gt Drug Identification Results gt Drug Identification Details Search POISINDEX Toxic Substance Listforthis Drug Name Search Drug Identification Methyldopa Drug Name Methyldopa Ingredients Methyldopa 250 MG NDC 00005 3850 34 Click the Search button to go directly to the Search Results for this drug in IDENTIDEX Color Orange Imprint M22 LL Shape Circle
15. PEDIATRICS PRIMARY CARE PULMONARY SPORTS MEDICINE TRAUMA UROLOGY VASCULAR Search Path AltCareDex Alternative Medicine Education gt Categories gt Category Results ACNE ACQUIRED IMMUNODEFICIENCY SYNDROME ATOPIC DERMATITIS HERPES ZOSTER ORAL HERPES SIMPLEX VIRUS PSORIASIS ROSACEA TINEA PEDIS Click the document title link to open the document Results can be viewed or printed See Printing Documents on page 30 for more information 2009 Thomson Reuters All rights reserved CHAPTER 10 FORMULARY amp HANDHELD PDA The Formulary and Handheld PDA tabs act as springboards to jump from Micromedex Healthcare Series to these additional helpful features FORMULARY ADVISOR Formulary Advisor is an easy to use electronic solution to manage your formulary Your hospital s formulary is vital for containing rising drug costs and promoting patient safety But managing and updating that formulary can be time consuming Plus ensuring clinicians consider your formulary when making prescribing and dispensing decisions can be a challenge Available as an add on subscription Formulary Advisor gives your staff an effective tool to manage your hospital s formulary and provide immediate access to the formulary throughout your entire facility Accessible via desktop PCs and PDAs handheld computers Formulary Advisor helps guide prescribing clinicians toward formulary drugs saving your pharma
16. Summary Documents E a ere Results 2 Results x where x the number of Clinical Checklist matches to your search term were found in DISEASEDEX General Medicine Summary Results 2 that database Click the link to view details DISEASEDEX Emergency Medicine Summary Results 2 goes to the Narrow Results page DRUGDEX Evaluations DRUGDEX Consults Results 13 Search Related Tradenames amp DRUGDEX Tradename List Search Related Tradenames Search Related Products links PDR Physicians Desk Reference Results 107 tiers a search when dicked MARTINDALE The Complete Drug Reference Results 2 the database for matches Martindale Products Search Related Product USP DI Drug Information for the Health Care Professional Results 37 Disease Information DISEASEDEX General Medicine Clinical Reviews Results 30 DISEASEDEX Emergency Medicine Clinical Reviews Results 58 DISEASEDEX Tests and Procedures Clinical Reviews Results 2 DISEASEDEX Studies and Alerts Results 2 DISEASEDEX Emergency Medical Abstracts from Rick Results 141 Bukata MD and Jerry Hoffman MD Lab Information Lab Advisor Results 14 Complementary amp Alternative Medicine i AltCareDex Alternative Medicine Education BACTERIAL PNEUMONIA When a document title is shown in AltMedDex Evaluations Results 5 Mat totale a AltMedDex Protocols BACTERIAL PNEUMONIA your search term Reproductive Risk SHEPARD S MYC
17. characters typed in the search field 3 When you see the drug in the Jump to drugs list click it to select the drug Search Path IV Single Compatibility 9 Single Drug Search Search term cefaz Carboplatin 44 Check Compatibility Cardarone intravenous Cardene IV Cardizem lea Carmustine Caspofungin acetate Caverject Cedocard Cefamandole nafate Cefazolin sodium Jump to drugs 4 Click the Check Compatibility button to begin the search To remove the drug from the search field and start over click the Clear button 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Compatibility Overview Search Path IY Single Compatibility gt Result Types Compariaity Overview Overview Solution Y Site Admixture Syringe Modify Your Search Cefazolin sodium more details and TPN TNA Common Solutions Compatibility Other Solutions Compatibility D5w i lonosol B in dextrose 5 il D5W Dextrose 5 Compatible Compatible D10wW Lactated Ringers Injection Compatible Dextrose 10 TE Tested Normosol M in dextrose D5LR 5 Compatible Dextrose 5 in lactated Compatible Ringers Peritoneal dialysis p DENS g solution Compatible Dextrose 5 in sodium Not Tested i i Plasma Lyte M in dextrose chloride 0 99 5 Compatible D5W 1 2 NS Dextrose 5 in sodium not Tested chloride 0 45
18. discussing diagnosis treatment and key points e Toxicology information information on the most common poisonings and drug overdoses including clinical effects treatment and range of toxicity e Alternative medicine information the most popular herbals and dietary supplements with information on class dosage adult and pediatric contraindications how supplied administration indications adverse effects pregnancy category and breast feeding e News Features include FDA announcements disease information clinical updates upcoming drug launches announcements Tools e Drug interaction tool Clinicians can check a patient s entire list of medications up to 32 at once for potentially harmful interactions with warnings on severity onset adverse effects probable mechanism evidence clinical management e Laboratory test information Details on laboratory tests including help in identifying appropriate tests interpreting test results monitoring drug levels collecting samples submitting tests and monitoring therapeutic levels and side effects e Disease database Includes pertinent data covering clinical presentation laboratory and diagnostic findings differential diagnosis pharmacologic and non pharmacologic therapeutics and appropriate disposition Content also includes evidence and recommendation ratings Simply go to the Healthcare Series main search page and click the Clinical Xpert link On this page you
19. evaluated information on worldwide drugs and related substances System enhancements allow quick and easy searching for pharmacological and therapeutic data synonyms and manufacturer s brand names What s in MARTINDALE The MARTINDALE database contains information on drugs in clinical use worldwide as well as selected investigational and veterinary drugs herbal medicines pharmaceutical excipients vitamins and nutritional agents vaccines radiopharmaceuticals contrast media and diagnostic agents medicinal gases drugs of abuse and recreational drugs toxic substances disinfectants and pesticides Sections of text summarize the relevant information followed if appropriate by referenced abstracts or reviews that expand upon the details given in the text or add additional information The contents may be categorized as follows e Generic drugs names including U S British and international approved names Synonyms chemical names e Molecular formula molecular weight CAS registry numbers e Pharmacopeias e Physical characteristics e Adverse effects and their treatment e Precautions including contraindications e Interactions e Pharmacokinetics e Uses and Administration including pharmacology and dosage e Preparations and brand names Preparations summaries of more than 70 000 proprietary products from 17 countries are included Information is provided on brand name manufacturer country of origin active constitue
20. i Expand All Collapse All available to you as you navigate through the document Oe LIFE SUPPORT The outline sections are shown as links and are fully navigable Click a LABORATORY MONTORING section name to jump directly to that section in the document You may ee or TET also scan the entire document by using the scrollbar INCLUDED SYNONYMS THERAPEUTIC TOXIC CLASS SPECIFIC SUBSTANCES When a document is opened the outline is shown in fully expanded F DESPRIFNON GEOGRAPHICAL LOCATION state Click the Collapse All link to compress the outline to the first level CUNCALEFFECTS of the outline Section names with a minus sign denote that S eee re IOVASCULAR additional sub sections exist below Click the section name with the 1 RESPIRATORY n NEUROLOGIC minus sign to view the sub sections For more information on document o Aa outlines see Floating Document Outlines on page 27 eee DERMATOLOGIC LABORATORY MONITORING MONITORING PARAMETER S LEVELS METHODS ABSTRACTS 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES PRINT SETUP AND PRINT READY Two print options are available from within a document Print Ready and Print Setup Print Ready Page Help Search Path Toxicolgy Topic Search gt Search Results gt Document SPIDER FUNNEL WEB back to top Expand All Collapse All OVERVIEW LIFE SUPPORT CLINICAL E
21. 3 to 6 5 concentrate 3 to 5 premixed infusions Solution Overview Solution overview information for single drug compatibility searches are comprised of Common Solutions The first table displays compatibility test results with the following common solutions D5W D5W Dextrose 5 DIOW Dextrose 10 e D5LR Dextrose 5 in lactated Ringers D5NS Dextrose 5 in sodium chloride 0 0 e D5W 1 2 NS Dextrose 5 in sodium chloride 0 45 e NS Normal saline Sodium chloride 0 9 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e 1 2 NS Sodium chloride 0 45 In cases where the drug was not tested with the common solution Compatibility Not Tested there is no link to further information Other solutions are grouped in the second table on the right and include test results where the chosen drug is listed as the primary or secondary agent in the test with the solution Note Solution results include those marked as a solution type but can also include Y Site admixture and syringe results that do not have a secondary agent T To view detailed test results for a specific solution click the link name of the solution If a solution has not been tested the Not Tested icon and description are shown and the solution name will not be an active link as no further details are available Y Site Overview Overview information for single drug Y Site compatibili
22. All rights reserved Searching with Synonyms When you do not find many relevant documents with your keyword search try entering synonyms Because the databases differ slightly you might find documents in one database using one term and documents in other databases using synonyms For example if you search for skin cancer you might also search for melanoma you will find different results Similarly the keywords lung cancer return somewhat different results than lung neoplasm Synonyms can be generic drug names versus proprietary names such as acetaminophen rather than Tylenol They can also be a common name versus a more clinical name such as head instead of cranium Expanding Search Keywords If you find few results your keyword may be too specific First try a more general synonym like cancer rather than neoplasm If you need to broaden your search term expand the form of your keyword or type only part of the word The Micromedex Healthcare Series application searches for an expanded match of the keyword containing that string of letters Consider the following examples e Appendix returns matches in about a dozen documents containing the index term appendix e Appendicitis returns many documents containing the index term appendicitis e Ina Find all keywords that Begin With search on the keyword Append Used as a search term this keyword generates multiple wildcard matches returns results for the following list o
23. Breadcrumb Compatibility Overview Modify Your Search Checking Compatibility For Click on drug names to see single compatibility e Amphotericin B cholesteryl Amphotec e Ampicillin sodium e Anakinra e Cefazolin sodium Amphotericin B cholesteryl Amphotec Ampicillin sodium Amphotericin B cholesteryl Amphotec Anakinra D Incompatible f Not Tested Amphotericin B cholesteryl Amphotec Cefazolin sodium Ampicillin sodium Anakinra Ampicillin sodium Cefazolin sodium Anakinra Cefazolin sodium Incompatible i Not Tested A Caution Variable Uncertain Summarized or high level results of the drug compatibilities are shown on the compatibility overview page The Y Site results page opens first by default To view a different result type Admixture or Syringe click type the tab link name for the desired Compatibility is denoted by an icon and simple description The full descriptions follow Icon Compatibility Full Description Compatible All studies showed these items as compatible A Caution Variable Study results vary details need to be evaluated D Incompatible All studies showed these items as incompatible or uncertain Q Uncertain Study results were inconclusive compatibility wasn t determined a Not Tested No study results were found Overview Page Navigation The Search Path or Breadcrumb The search path also known as a breadcrumb di
24. CN CHLOROACETOPHENONE 076573 LACRIMATORS CS O CHLOROBENZYLIDENE MALONITRILE Result 077104 UNKNOWN TYPE OF ADHESIVE GLUE CEMENT OR PASTE Or scroll to the number using the scrollbar located on the right side of the list 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Toxic Substance Search Results Search results for a toxic substance search are all presented in tabular format with links to related items The information displayed will vary depending on the search type selected Product or Substance Search Results Note The initial Product or Substance search looks only for products substances or synonyms available in the United States or world wide A product not found from an initial search may be available outside of the United States Search non US products by clicking the Click here if you would like to search for this term in non US products link T When no matches are found for the search term or phrase the following message is shown No data was found for this search term If you are unsure of the spelling try typing in only the first few letters of the term Click here if you would like to search for this term in non US products Tip If the search term you used found matches first for US and world wide products but the product you are looking for is available outside of the United States click the Results ea from other countries link to start a
25. Clinical References and Calculators m Coagulation Pathways amp Factors Provides the factor deficiencies in coagulation disorders which have the disorder such as Christmas Disease and the deficient coagulation factor related to it such as IX It also give the intrinsic and extrinsic clotting pathways 2009 Thomson Reuters All rights reserved Alveolar Arterial Oxygen Gradient Allows you to calculate the alveolar oxygen concentration and gradient with notes related to the results obtained You can also determine atmospheric pressure for a specific area or country Glasgow Coma Scale Results provide the best motor verbal and eye opening response obtained for an adult and what that response converts to in the score Also provides scores for children under one year of age and over one year of age with scores to help you determine the severity of injury Pulmonary Function Parameters Shows normal values for adults such as tidal volume and total lung capacity Dental Tooth Counter A graph showing the permanent teeth upper and lower with numbering for reference Menstrual Cycle Normal Patterns Provides the normal patterns of a menstrual cycle and ovulation cycle Hair Changes by Agent Drugs that cause hair changes alopecia color changes hirsutism hyperpigmentation hypertrichosis and hypopigmentation Dietary Considerations and Guidelines Most of these tools simply require you to select the tool by name
26. ClinicalPoints concise overviews on emergency conditions and treatments covering e Treatment e Diagnosis e Key Points Clinical Reviews data pertinent to diagnostic and therapeutic purposes covering e Summary information e Presentation by body system e Complications e Associated conditions e Laboratory Radiologic data e Diagnostic aids and differential diagnosis e Treatment recommendations e Disposition e References 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS Pre hospital Care Protocols treatment guidelines that consider patient history symptoms and signs The protocols cover e Presentation e Stabilization e Base Contact e Special Consideration e References Abstracts definitive source of literature review covering a broad scope of topics compiled by Rick Bukata MD and Jerry Hoffman MD DISEASEDEX General Medicine Evidence based current disease information DISEASEDEX supports disease management and treatment decisions in ambulatory and inpatient care settings General Medicine content enables clinicians to quickly reference the most current treatment of choice information at the point of care to help minimize errors prevent unnecessary tests and procedures reduce treatment costs and improve patient outcomes Each General Medicine document covers Management highlight Prognosis Background Advising the Patient Diagnosis Follow up Treatment Prevention and Screening
27. Epinephrine Dosing Calculator Adult Epinephrine Dosing Calculator Pediatric Heparin Dosing Calculator IV Rate Calculator Nitroglycerin Dosing Calculator Nitroprusside Dosing Calculator Norepinephrine Dosing Calculator Adult Norepinephrine Dosing Calculator Pediatric Measurement Calculators and Conversions 2009 Thomson Reuters All rights reserved DOSING TOOLS CALCULATORS NOMOGRAMS amp REFERENCES Body Weight amp Surface Area Calculator Body Mass Index Calculator Body Weight Ideal Conversions Factors Equivalents Practical Metric Conversions Calculator Milliequivalents SIU Conversion Calculator Temperature Conversions DISEASE Clinical Reference and Calculators Alveolar Arterial Oxygen Gradient Coagulation Pathways and Factors Dental Tooth Counter Glasgow Coma Scale Hair Changes by Agent Menstrual Cycle Normal Patterns Pulmonary Function Parameters Dietary Considerations and Guidelines Caffeine Content of Foods Calcium Content of Foods lon Content K Ca Fe Salts Iron Content of Foods Lactose Content of Foods Potassium Content of Foods High Potassium Content of Foods Low Tyramine Containing Foods Vitamin K 1 Content of Foods Vitamin Synonyms Differential Diagnosis Agranulocytosis Alopecia Anion Ga
28. Martindale The Complete Drug Refer ence Material Safety Data Sheets MSDS from USP DI P amp T QUIK Reports Physicians Desk Reference PDR POISINDEX System REPRORISK System TOMES System ToxPoints System AltCareDex System Patient Education for Complementary and Alternative Medicine As part of the Complementary and Alternative Medicine CAM Series AltCareDex documents offer fully referenced patient counseling materials written and peer reviewed by representatives from both conventional Western medicine and the alternative medicine communities What s in AltCareDex e Dietary Supplement documents e Disease state Medical condition documents e Therapy documents Dietary Supplement documents Dietary supplement documents provide concise information on indications dosage storage interactions side effects and warnings associated with the most frequently used herbal medicines vitamins minerals and other CAM related substances Disease States Medical Condition documents 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES These documents provide information on common diseases or medical conditions and how to treat them using CAM therapies A description of the condition causes signs and symptoms wellness recommendations and complementary treatments are presented Therapy documents Therapy or modality documents offer overviews on biofeedback aromat
29. Medicine Li F POISINDEX Managements Li TOMES System Li V REPRORISK System DISEASEDEX Emergency Medicine E M DISEASEDEX General Medicine O 7 Lab Advisor O E Summary Documents 0 When you have selected the databases to be included in your search type your keyword and click the Search button Multiple Keywords Usually you will find the most documents by entering only one keyword However you may want to enter more than one word in the following situations To narrow your search particularly if one of the terms is very broad or if the combined words describe a particular condition or disease such as Sickle Cell Anemia To find a compound drug For example searching on acetaminophen butalbital will eliminate other acetaminophen combinations See Note Note Specific drug interactions may be found using the multiple or single interactions search from the Interactions tab which searches the DRUG REAX and the AltMed REAX for the Professional databases which are not included in the main keyword search Wt Side by side drug comparisons are available from the Drugs tab the Compare Drug Summaries menu option See Compare Drug Summaries on page 43 for more information Two or more narrowly related keywords may not return matches for your search However if the keyword phrase describes a specific illness drug or treatment you will likely find documents 2009 Thomson Reuters
30. NOMOGRAMS amp REFERENCES LABS Cholesterol and Triglycerides Creatinine Clearance Phenytoin Level Adjustment Calculator Serum Chemistry Normal Values Synovial Fluid Analysis Measurement Calculators and Conversions Body Weight amp Surface Area Calculator Body Mass Index Calculator Body Weight Ideal Conversions Factors Equivalents Practical Metric Conversions Calculator Milliequivalents SIU Conversion Calculator 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved INDEX Numerics 1 2 NS 128 A Acute 89 Admixture 122 124 128 131 AltCareDex System 141 147 alternative medicine 141 Alternative Medicine Summary Information 20 AltMedDex System 148 AltMedDex Points System 149 AltMedDex Protocols 148 AltMed REAX for the Patient 149 B Begin With shortcut 20 Best Matches 24 boolean search operator 18 breadcrumb 12 27 49 126 Cc Calculators 32 41 41 Antidote Dosing 32 Clinical References amp Calculators 32 Alveolar Arterial Oxygen Gradient 33 Coagulation Pathways amp Factors 32 Dental Tooth Counter 33 Glasgow Coma Scale 33 Hair Changes by Agent 33 Menstrual Cycle Normal Patterns 33 Pulmonary Function Parameters 33 Dietary Considerations amp Guidelines 33 Caffeine Content of Foods 34 Calcium Content of Foods 34 lon Content K
31. Patient Ed Formulary Preview your Clinical Xpert access EJ calculators Rag su Search Path Calculators Select a Calculator Antidote Dosing and Nomograms Clinical References and Calculators Dietary Considerations and Guidelines Differential Diagnosis Dosing Tools Drug Classifications Drug Comparisons Immunizations amp Prophylaxis Laboratory Values Measurement Calculators and Conversions Pediatric and Pregnancy References All of the calculators dosing tools references nomograms that have been included in the Healthcare Series application can be found from the Calculators menu option on the Main tab or from the calculators link or button E available on every page Antidote Dosing and Nomograms li Antidote Dosing and Nomograms m 4 Toxicity Nomograms i Alcohols Ethylene Glycol Blood Level NAC Dosing for Acetaminophen Overdose Ethanol IV Dosing for Methanol Ethylene Glycol Overdose Clinical References and Calculators Most of these tools simply require you to select the tool by name and click the Go button The resulting report can be viewed or printed for your records or reference See Printing Documents on page 30 for more information on printing Coagulation Pathways amp Factors Alveolar Arterial Oxygen Gradient Glasgow Coma Scale Pulmonary Function Parameters Dental Tooth Counter Menstrual Cycle Normal Patterns Hair Changes by Agent
32. REPROTEXT Database e REPROTOX e Shepard s e TERIS e Material Safety Data Sheets MSDS from USP e Summary Documents ToxPoints System For detailed information about each of the databases See Micromedex Healthcare Series Databases on page 147 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION SPECIFIC TOPIC SEARCH Use the Specific Topic Search to go directly to perform a full text search within specific outline sections of toxicologic information databases Databases available from this option are e POISINDEX Toxicologic Managements e MEDITEXT Medical Managements e HAZARDTEXT Hazard Managements Search results show the document title the section name and a snapshot of the text where the search terms were found You have the option of opening the document at the beginning click on the title link or opening the document directly at the specified outline section click the section name link Create a Specific Topic Search 1 On the Toxicology tab select the Specific Topic Search menu item 2 Select the toxicology database you wish to search The available outline sections change as the database is selected 3 Type the exact term to search 4 Select the type of information you want from the available topic checkboxes The application searches the selected checked topics for information related to your keyword s All topics are selected by default To Uncheck all of
33. analytical methods e References e Author information ToxPoints System The ToxPoints System provides brief highlights of clinical effect treatment and range of toxicity information The ToxPoints System delivers answers quickly and efficiently The System also links directly to the more in depth POISINDEX System Toxicological Managements available only with a current POISINDEX subscription 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved APPENDIX B DOSING TOOLS CALCULATORS NOMOGRAMS amp REFERENCES Thomson Reuters publishes clinical decision support databases and tools The Micromedex Healthcare Series provides a wide range of tools and calculators tailored to meet the needs of clinicians and healthcare professionals including information related to drugs acute care toxicology complementary and alternative medicine and patient education The following tables list the dosing tools calculators nomograms and references available on the Main gt Calculators tab in Micromedex Healthcare Series DRUGS Dosing Tools ACLS PALS Guidelines Dobutamine Dosing Calculator Dopamine Dosing Calculator Epinephrine Dosing Calculator Adult Epinephrine Dosing Calculator Pediatric Heparin Dosing Calculator IV Rate Calculator Nitroglycerin Dosing Calculator Nitroprusside Dosing Calculator Nore
34. anticoagulation Either intravenous unfractionated heparin or LMWH may be used to treat DVT Heparin is usually given for 5 to 10 days in combination with warfarin begun atthe same time as or soon after starting heparin therapy heparin is continued until the INR is therapeutic Thrombolytic agents usually are reserved for hemodynamically unstable patients with a massive limb threatening DVT in whom the benefits of treatment outweigh the risks of serious bleeding complications Mechanical and surgical means of thrombus extraction may be required for patients in whom thrombolytic therapy fails or is contraindicated or for patients with a limb threatening iliofemoral thrombosis Approaches to prophylaxis include graduated compression stockings intermittent pneumatic compression and LMWH or unfractionated subcutaneous heparin Sequential screening regimens may be important in high risk patients Drug Therapy e Anticoagulants Overview Treatment In the initial treatment of a lower extremity DVT start a vitamin K antagonist bsequent to the initiation of a low molecular weight heparin or unfractionated saAsaatment day 1 aa e the aoa h eye Document Outlines The document opens with the document outline displayed on the left side of the screen The outline will float on the page so it is always DEEP ENOUS THR back to top Expand All Collapse All available to you as you navigate through the document The outline sectio
35. documents Search results show the document title the section and a snapshot of the text where the search terms were found You have the option of opening the document at the beginning click on the title or opening the document directly at the specified section click the section name link Create a Specific Topic Search 1 On the Search Specific Disease Topics page select DISEASEDEX General Medicine or DISEASEDEX Emergency Medicine or DISEASEDEX Tests and Procedures for your search The list of available document sections changes according to the selection made 2 Type the exact term to search Typically the search term is a disease or symptom 3 Select the type of information you want from the available checkboxes and then click the Search button The application searches the selected checked document outline sections for matches to your search term s All document outline sections are selected by default To quickly de select all of the checkboxes click the Uncheck All link Once unchecked you can then select the document sections you wish to search Disease Topic Search Choose One Database to Search DISEASEDEX Emergency Medicine DISEASEDEX General Medicine DISEASEDEX Test and Procedures Clinical Reviews Search document for this exact term DT Search Within Check All Uncheck All C Definition Treatment CI Epidemiology C Prognosis C Etiology Pathophysiology C Dispo
36. e Category B evidence is based on data derived from Meta analyses of randomized controlled trials with conflicting conclusions with regard to the directions and degrees of results between individual studies Randomized controlled trials that involved small numbers of patients or had significant methodological flaws e g bias drop out rate flawed analysis etc Non randomized studies e g cohort studies case control studies observational studies Category C evidence is based on data derived from Expert opinion or consensus Case reports or case series e No Evidence Strength of Recommendation In some lab documents a Strength of Recommendation link is shown This provides the reader with a weighting that they can attach to the recommendation in the document The rating is organized into five classes Class Ila Ilb Ill and Class Indeterminant Click the link to view the definition of the class e Class Recommended The given test or treatment has been proven to be useful and is indicated in all cases e Class Ila Recommended In Most Cases The given test or treatment is generally considered to be useful and is indicated in most but not all cases e Class Ilb Recommended In Some Cases The given test or treatment is not generally considered to be useful It may be indicated in some but not most cases Class lll Not Recommended The given test or treatment has been proven to be harmful
37. for the Consumer Drug Information in Lay Language Easy to understand in depth materials to help educate your patients about medications and their proper use An educational resource to match patients proactive role in their care Detailed Drug Information for the Consumer Drug Information in Lay Language provides patient oriented drug information to help patients understand and successfully follow their drug regimens Written at a 12th grade literacy level documents provide greater detail than most patient education leaflets and include brand names descriptions proper use precautions and side effects Instructions for how to handle missed doses are included as are guidelines for when to seek medical assistance or supervision e Offers the most comprehensive patient education information available providing greater detail than typical pharmacy leaflets Provides detailed drug information to help reinforce treatment instructions and patient understanding DISEASEDEX Emergency Medicine Comprehensive source of urgent and acute care information DISEASEDEX Emergency Medicine previously named EMERGINDEX provides actionable information extracted from an extensive library of medical journals With over 40 000 key terms and synonyms Emergency Medicine helps clinicians quickly access current and crucial data organized by both condition and diagnosis DISEASEDEX Emergency Medicine includes Emergency and Acute Care Summaries see
38. in the Jump to field The list moves to the position in the list that most closely matches the letters typed For example typing en positions the list to the Enzyme measurement test see example Open a lab by clicking the Select button with the test name highlighted Lab Advisor documents include section outlines to aid in fast navigation throughout the document See The Lab Advisor Document Outline on page 115 for more information Print the document See Printing Lab Advisor Documents on page 116 Browse Lab Advisor EP Electrophoresis Ehrlichiosis Electrolytes measurement Electrophoresis Electrophoresis measurement Elevated blood lead level Elevated lead level En zyme measurement 2009 Thomson Reuters All rights reserved The Lab Advisor Document Outline All information in Lab Advisor documents is organized into a standard outline structure The outline is shown in a box on the left side of the document and can be used to jump toa different section outline topic within the document As you scroll through the document the outline moves with you so it is always visible and available for quick navigation to another point in the document Common top level outline sections are Synonyms e Reference Range e Indications Common Panels e Drug Lab Interactions e Clinical Notes e Contraindications e Collection Storage Information e Test Definition e Test Methodology L
39. information e The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination e Notes for the test if applicable are shown in red text at the top of the detailed study information In cases where the drug was not tested with the solution listed Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Syringe Overview tab name link TPN TNA Details Detail information for single drug TPN 2 in 1 total parenteral nutrition compatibility is shown in the first table followed by TNA 3 in 1 total nutritive admixture compatibility Jump to the TNA 3 in 1 table by clicking the Go to TNA 3 in 1 results link Note TPN and TNA results are not result type specific They can be a Y Site solution or admixture result Results are comprised of all compatibility tests where the drug name searched is either the primary or secondary agent and the result is a TPN or TNA solution aP 23 M 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Search Path IV Single Compatibility gt Compatibility Overview gt Compatibility Details Modify Your Search TPNITNA Detail TPN 2 in 1 Go to TNA 3 in 1 results Aminosynil Compatible Y Site Notes Two TPN formulas peripheral line and central line formulas based on Aminosyn Il we
40. of Toxicity to be uniquely sensitive to funnel web spider venom compared with other vertebrates 2Monkeys given Treatment strangly suspected of being a funnel web spider should be observed for 18 hours and discharged Go directly to the information by clicking the link of the topic 9 0 PHARMACOLOGYITOXICOLOGY SPIDER FUNNEL WEB back to top 9 2 TOXICOLOGIC MECHANISM Expand All Collapse All OVERVIEW LIFE SUPPORT CLINICAL EFFECTS LABORATOR YMONITORING TREATMENT OVERMEW RANGE OF TOXICITY SUBSTANCES INCLUDED SYNONYMS THERAPEUTIC TOXIC CLASS SPECIFIC SUBSTANCES DESCRIPTION GEOGRAPHICAL LOCATION CLINICAL EFFECTS SUMMARY OF EXPOSURE VITAL SIGNS HEENT CARDIOVASCULAR RESPIRATORY NEUROLOGIC GASTROINTESTINAL GENITOURINARY ACID BASE HEMATOLOGIC DERMATOLOGIC LABORATORY MONITORING MONITORING 2009 Thomson Reuters All rights reserved A SUMMARY The Sydney funnel web spider contains a lethal neurotoxin found in the venom ofthe male species which initially enhances then inhibits skeletal motor nerves Hodgson 1997 Only primates and new born mice have been found to be susceptible to the effects of the venom B The venom contains a high level of GABA a spermine complex lactic acid and a range of other chemicals including tyramine and octopamine The venom is acidic C Venom from the funnel web spider contains many acylp
41. older 650 mg ORALLY every 4 to 6 h maximum 3 9 g 24 h Dysmenorrhea age 6 to 11 y 325 mg ORALLY every 4 to 6 h maximum 2 6 9 24 h Fever 10 to 15 mg kg dose ORALLY every 4 to 6 h maximum 5 dosesiday Fever age 6 to 12 y 325 mg ORALLY every 4 to 6 h maximum 2 6 g 24 h G ZOA Select Databases When you know that the answer you are looking for is in a specific database within Micromedex Healthcare Series you can pinpoint your search by using the Select Databases button Select Databases The Main keyword search page expands to show the databases available for inclusion exclusion in your search All subscribed databases are selected by default Uncheck the databases you do not wish to include in your search Quickly de select uncheck all databases by clicking the Uncheck All link 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES For an overview of each of the databases click the i information icon i to pop upa database definition Main Keyword Search Search Drug Toxicology Disease and Labs databases for Search Find all keywords that Exactly Match End in an asterisk Wiah aceta for Begin With search Begin With Search checked databases Hide Databases Check All Uncheck All F DRUGDEX System E Index Nominum Li F MARTINDALE i P amp T QUIK Reports Li F PDR o Detailed Drug Information for the Consumer F MSDS from usp Gi Alternative
42. or substance to view treatment and management information Click the POISINDEX Management link to view treatment and management information Active Ingredient and Codes Search Results The Active Ingredient and Codes search performs a contains search Results retrieved for this type of search are shown sorted alphabetically by trade name Results are shown in table format and display e tradename e manufacturer e country e AAPCC code e POISINDEX Management s If more than one page of results are found navigate to additional pages using the page number link or First Previous or Last page links 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION Patient Ed Handheld PDA Main bitty Toxicology Faure Labs IV Compatibility Need training to access clinical information at the point of care E Print Ready Calculators Rg Subscription Details Page Help Interactions Formulary Search Path Toxic Substance List Search gt POISINDEX Product List Showing Results 1 through 50 of 4088 First Previous 1 2 3 4 5 6 7 8 9 10 Next Last Trade Name Manufacturer Country AAPCC Poisindex Managementis Manufacturer contact information American Latex 1 Coat Exterior Latex Enterprise Paint United States 254368 PAINT HYDROCARBONS 1 Coat Flat Interior Latex Enterprise Paint United States 254368 PAINT 1CoatLatex Semi Gloss Enterprise Pain
43. products available in the United States or world wide and outside of the United States The search always presents results for products available in the US or world wide first an Note The initial Product or Substance search looks only for products substances or synonyms available world wide or in the United States T If you are searching for a product or substance only available outside the United States click the Results from other countries link located near the top left side of the page just below the Search results for lt your search term s gt e Tip A product substance or synonym may have a match in both US and non US lists but the US and world wide lists are always shown first Find non US products by clicking ed the Results from other countries link Imprint Code Search Results The Imprint Code search performs a contains search Results retrieved for an Imprint Code search are shown sorted alphabetically first by product name then by code Results are shown in table format and display e imprint e tradename e manufacturer e country e AAPCC code e POISINDEX Management s If more than one page of results are found navigate to additional pages using the page number link or First Previous or Last page links 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Main litt Toxicology AMEER Labs IV Compatibility Interactions Patient Ed Formulary Handheld
44. search for non US products a7 The following is an example of search results for a Product or Substance search for DRANO Hope traina to access chacal Kitoc ination al the pont of Care E Pretend E cadcolerces Fj tvhacrincian Qasaila E eoaetie n Search Path Product List Opon All Chye At lt Synonyms 15 Results Product or Substance 20 Results Product or Substance Manntacturer Country Anpoc Potsinde Managerent s Vano Clon Remover Liawd Drain Oponor Laid 8C Johnson Canada 011289 CORROSIVES ALKANE United States HEPOCHLOBITES AD BELATED AGENTS Crane Chon Perret innate Do ain Crowes tert 8C Johnson Cansda 011209 CORROSVET ALKAUNI United States HP OSHLORITES AND RELATED AGENTS Orano Qual force Foamer Clon Remit Chamber 1 Cinar SC Johnson United States 011209 GORROGIVES ALKAUINE tom HEOCHLORTER AND f ANIORIIE AND NONIONIC Drano Dual Force Foamer Clo Remover Chamber Cinar SC Johnson United States 011209 toom HYDROGEN PEROXIDE BC Johnson Canada 011289 eeroninuee prano rnamer Granutos United states ur i aue NN a rye aA a eres een SAND a aa BELATED AGENTS DETERGENTS AND SOAPS ANIONIC AND NONIONIC Orano Professional Strereth Kichun Crystals Coa Harmaat EC Johnson Canada 011209 CORROSIVEEALKALINE Groner vrith Aluminum Chins United States TRATES Bccontinves J orange P 50 Johnson Uplted States 077914 DETERGENTS AND Soaps ANIONIC AND NONIONIC att Un toerrncrves Cina
45. searches are shown in a five column table The first column contains the drug name the concentration and the manufacturer s name The second column shows the secondary agent name concentration and manufacturer s name The third column lists the compatibility icon and description The fourth column displays the physical compatibility chemical stability if applicable and storage information The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination Notes for the test if applicable are shown in red text at the top of the detailed study information In cases where the drug was not tested with a listed drug Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Syringe Overview tab name link Results can be viewed or printed See Printing Documents on page 30 for more information 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Single Drug Search Single drug IV compatibility searches calculate results where the drug is listed as either the primary or secondary agent in the comparison 1 From the IV Compatibility tab verify that the Single Drug Search is selected 2 Type the drug you wish to check in the Search term field If you are unsure of the spelling type the first few letters The list of drugs positions itself according to the
46. separate subscription for materials on condition treatment follow up care and continuing health concerns AltCareDex Alternative Medicine Education provides clinicians with complementary and alternative medicine patient education materials such as dietary supplements herbal remedies and care amp condition information Formulary Formulary If you are a subscriber to Formulary Advisor you will see the Formulary tab This tab allows you to jump from Healthcare Series directly to Formulary Advisor for real time point of care access to your formulary Handheld PDA Handheld PDA Click the Handheld PDA tab to register and download Clinical Xpert for your PDA Personal Digital Assistant Clinical Xpert is an easy to use PDA tool that provides trusted evidence based information to Palm OS and Pocket PC devices 2009 Thomson Reuters All rights reserved UNDERSTANDING THE BASICS Evidence Xpert The Point of Care Interface rhedais MICROMEDEX Healthcare Series MICROMEDEX Main Drugs Toxicology Disease Labs IV Compatibility Interactions Patient Ed Formulary Handheld PDA Designed specifically for point of care clinicians Evidence Xpert the point of care solution makes it easier than ever to access the information you trust when and where you need it The browser based interface is intuitive and easy to use providing quick access to summary level content at any point in the pat
47. symptomatic and have a high clinical Strength of Recommendation suspicion for myocardial infarction but who have an Strength of Evidence initially nondiagnostic ECG u Screen for right ventricular infarction in patients with an inferior wall myocardial infarction and hemaodynami compromise by using right precordial chest leads Links to referencesicitations detect ST segment elevation in lead V R 1 Each item is shown with the corresponding Strength of Recommendation and Strength of Evidence icon to visually portray the validity and strength associated with the information Clicking the icon opens the full legend Strength of Evidence Strength of Evidence Category Category A evidence is based on data derived from Meta analyses of randomized controlled trials with A homogeneity with regard to the directions and degrees of results between individual studies Multiple well done randomized clinical trials involving large numbers of patients Category Category B evidence is based on data derived from Meta analyses of randomized controlled trials with B conflicting conclusions with regard to the directions and degrees of results between individual studies Randomized controlled trials that involved small numbers of patients or had significant methodological flaws e g bias drop out rate flawed analysis etc Nonrandomized studies e g cohort studies case control studies observational studies Category Category C
48. the Search Related Tradenames link searches then opens a tradename list table from the DRUGDEX database For more information on the Tradename List see Trade Generic Lists on page 47 Products from the Search Related Products link searches then opens either the Martindale or POISINDEX Products list depending on which database link was clicked For more information on products see Trade Generic Lists on page 47 Imprint Codes from the Search Imprint Codes link searches then opens the IDENTIDEX Toxicology List For more information see Types of Toxic Substance Searches Available on page 66 2009 Thomson Reuters All rights reserved Narrow Results Searches can result in matches found in more than one document but allin the same database When this occurs the Narrow Results page is displayed by clicking the Results x link on the Initial Results page The Narrow Results page is organized into groups according to where the search term was found in the document Titles keyword matches to document titles are always listed first on the Narrow Results page Synonyms keyword matches where the keyword has been associated toa document as a synonym or index term Synonyms are listed after any title matches Related Terms are documents containing the MICROMEDEX HEALTHCARE SERIES Drugs Toxicology Disease Labs 1V Compatibility Interactions Patient Ed Formul
49. the point of care Using information from leading IV compatibility expert Lawrence Trissel MS FASHP IV INDEX presents over 50 000 compatibility results for solution Y Site admixture or syringe administration Single drug or multiple drug compatibilities can be calculated WSIS MICROMEDEX Healthcare Series MICROMEDEX Main Drugs Toxicology Disease Labs IV Compatibility Interactions Patient Ed Formulary Handheld PDA Ej Subscription Details Page Help Search Path IV Multiple Compatibility Multiple Drug Search Single Drug Search Check Compatibility Clear Search term Jump to drugs 2 Deoxycoformycin 2 Fluoro ARA AMP 6 MP Add Abbokinase Abciximab Remove Acetazolamide sodium KTT Acetylcarnitine Acetylcysteine Multiple Drug Search Tests for compatibility are based on e Other drugs and solutions in Y Site administration e Administration as part of an Admixture e Other drugs and solutions administered by Syringe 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Steps to Create a Multiple Drug Search 1 From the IV Compatibility tab verify that the Multiple Drug Search is selected 2 Type the tradename or generic drug name of the first drug you wish to check for compatibility in the Search term box If you are unsure of the spelling type the first few letters The list of drugs narrows down to match your term as you type the char
50. to communicate their condition to you is complicated especially if they take one or more prescription drugs Often they have their medications with them but rarely in original or identifiable packaging The IDENTIDEX System facilitates the quick accurate identification of unknown drugs by imprint code or slang term A match is further confirmed by physical characteristic descriptions product photos where available and accompanied by ingredient and manufacturer data The System provides links to toxicologic managements in the POISINDEX System to assist with emergencies TOXIC SUBSTANCE LISTS To begin a search from the Toxicology tab select the Toxic Substance List option Main Drugs See Disease Labs iV Compatibility interactions Patient Ed Formulary Handheld PDA Need training to access clinical information at the point of care a Calculators Ei Subscription Details a Page Help Search Path Toxic Substance List Search Search Product or Substance Imprint Code Active Ingredient and Codes Product ID Look up AAPCC Codes You are presented with the Toxic Substance List Search page You can choose from four different types of searches depending on what information you are looking to retrieve 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Types of Toxic Substance Searches Available Product or Substance The Product or Substance search is only a
51. 00220 9313 will return O0220 9313 01 0O0220 9313 02 00220 9313 03 and so on CAS numbers Chemical Abstracts Service CAS registry numbers standard format is 2 to 6 digits then 2 digits followed by 1 digit all separated by a dash such as 54 06 8 or 361377 29 9 DIN codes Drug Identification Number DIN numbers can be an 8 digit code or 5 digits then 4 digits separated by a dash example 00004588 or 00002 6069 EPA codes Environmental Protection Agency codes Type the code exactly e g 1332 58 7 or 475 237 or 4 30 869 UPC codes Universal Product Code UPC numbers follow no standard format or layout Be sure to type the code exactly including spaces letters and dashes for example O 49424 13610 O or XN 1014 3526 3 or 38753 31590 Other codes that can be searched are PCP Pest Control Product CRN California Registry Number and Fertilizer Act Search Active Ingredient and Codes 1 Type the ingredient or the full code in the Search field a7 Tip When searching multiple ingredients enter each ingredient separated by a space Do 2 not type the word and or use any Boolean operators ed For example ACETAMINOPHEN CODEINE You can search on as few as one alphanumeric characters however performance may be affected when retrieving extremely large result sets 2 Click the Active Ingredient and Codes button For information on Active Ingredient and Codes search results
52. 3 Registry Number NDC 00005 3849 Physical Description Imprint LI M21 Form coated tablet Color peach Shape Circle Size 0 313 Search Drug Identification Drug Images Database 1 Enter the descriptive information in the appropriate input boxes Note If any search parameters are entered for Description Shape or Pattern other than the a Z default of ALU the Drug Images Database will be searched The application will automatically search the IDENTIDEX System if only the Imprint Code information is typed If only imprint code information is known and you wish to search the Drug Images Database click the Drug Images option button then the Search button 2 The more parameters you enter the more you will limit your search results Colors You can choose to search for more than one color by holding down the Ctrl key while selecting the colors Selecting multiple colors searches for drugs that contain ANY of the colors selected in any combination In the following example the drug could have any combination of the three colors Black and Blue and Brown OR Black and Blue OR Black and Brown OR Black OR Blue and so on to be considered a match Colors All Colors Other CTRL click to select more than one color 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 3 When all known characteristics of the drug have been defined click the Search button
53. 6 Search by LOINC Code Search for a lab document by the LOINC code 1 Verify that LOINC Code is the option selected in the Search for listbox 2 Type the full LOINC code in the text box A valid LOINC Code must be typed as 1 5 digits followed by a dash and ending with a single digit 3 Click the Search button For example if you searched on 2435 9 using this method Lab Advisor finds a match for Serum protein electrophoresis Some lab tests have multiple LOINC codes associated Using the Serum protein electrophoresis as an example there are three LOINC codes attached Code 20577 3 Short Name Prot SerPl Elph mCnc e Code 13980 8 Short Name Alb SerPl Elph e Code 24351 9 Short Name Prot Elph Pan Ser Lab Advisor documents include section outlines to aid in fast navigation throughout the document See The Lab Advisor Document Outline on page 115 for more information Print the document See Printing Lab Advisor Documents on page 116 Browse the list of Tests Using the Browse feature you are able to simply view the list of tests available in Lab Advisor The list is displayed in alphabetical order and shows test names as well as applicable synonyms Using the scrollbar move up or down in the list If you find a test you wish to view click the lab name so it is highlighted then click the Select button Another option for browsing labs is typing the first few letters of the lab name
54. All product or substance names that begin with the search term are sorted alphabetically and shown first in the search results When multiple search terms are used the product name beginning with the entire phrase is shown first Product or substance names that contain the search term are sorted alphabetically and shown below a gray separator bar in the list of results See the example on page 70 for Face Drano When multiple search terms are used the product name containing all of the terms in any order are shown below the gray separator bar Links Synonyms 15 Results Product or Substance 20 Results Product or Substance Manufacturer Country AAPCC _Poisindex Management s Drano Clog Remover Liquid Drain Opener Liquid SC Johnson Canada 011289 CORROSIVES United ALKALINE States HYPOCHLORITES AND RELATED AGENTS Drano Clog Remover Liquid Drain Opener Liquid SC Johnson Canada 011289 CORROSIVES j N The Product List Click the Product or Substance name link to view ingredient information availability amp manufacturing information and a physical descripion Images if available are also included 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Main 7 UIUGS Cnicuyp visease 7 Lavs 7 Iv Compatioiity 7 interactions 7 rauented 7 Formulary nananeld PDA tri t S Clinical informati re FEM Print Ready EF calculators f Subscription Details Page Help Searc
55. BASE DESCRIPTIONS AltMedDex Protocols provides in depth information for healthcare professionals on the efficacy and use of complementary and alternative therapies to treat disease states and common health conditions Documents are written and reviewed by alternative medicine Naturopathic Doctors and conventional medicine MDs PharmDs RNs practitioners AltMedDex Protocols contains e DISEASE CONDITION OVERVIEW e Etiology e Risk Factors Prognosis Signs and Symptoms e Differential Diagnosis e Monitoring Parameters e WESTERN MEDICAL THERAPIES e INTEGRATIVE MEDICINE STRATEGY e COMPLEMENTARY AND ALTERNATIVE THERAPIES e Herbal Therapies e Dietary Supplements e Complementary Therapies e Wellness Recommendations e REFERENCES AltMedDex Points System The AltMedDex Points System provides brief highlights of dosing indications contraindications adverse effects drug interactions therapeutic class pregnancy and lactation for herbals vitamins minerals and other dietary supplements The AltMedDex Points System delivers answers quickly and efficiently The System links directly to more in depth information in AltMedDex evaluations available only with a current AltMedDex subscription AltMed REAX for the Patient Herbal and Dietary Supplement interaction information AltMed REAX for the Patient provides information to consumers on interactions related to herbal medicines and other dietary supplements Information is
56. BS0ANTIHISTAMINES LIM 14 Meclizine Hydrochloride Lederle Laboratories gansa 003720 POISINDEX DOCBS0ANTIHISTAMINES Li M 13 Meclizine Hydrochloride Lederle Laboratories rn 003720 POISINDEX DOC68QANTIHISTAMINES L M 35 Medroxyprogesterone Acetate Lederle Laboratories Sae 202000 POISINDEX D0C202PROGESTINS mde eee Lederle Laboratories or UdI United 1zzaan POISINDEX DOC1845SKELETAL MUSCLE RELAXANTS If multiple drugs match the characteristics searched you will see the drugs which matched your search criteria displayed in a tabular format You can quickly scan for the imprint trade name manufacturer country of manufacture AAPCC code and POISINDEX Management document title link Click the trade name link to view the drug information Click the POISINDEX Management title link Related Documents to view toxicologic management information 2009 Thomson Reuters All rights reserved DRUG INFORMATION Search Path Drug Identification gt IDENTIDEX gt POISINDEX Product List 4 Previous Methyldopa Net Related Document METHYLDOPA POISINDEX Managements Ingredients Active Ingredient Methyldopa 125 MG Excipients modified food starch Ethylcellulose hydroxypropyl methylcellulase Magnesium Stearate microcrystalline cellulose pvp Titanium Dioxide yellow 6 Availability amp Manufacturing Availability United States Manufacturer Lederle Laboratories Product ID 3397646 AAPCC Code 07777
57. Ca Fe Salts 34 Iron Content of Foods 34 Lactose Content of Foods 34 Potassium Content of Foods High 34 Potassium Content of Foods Low 33 Tyramine Containing Foods 34 Vitamin K 1 Content of Foods 33 Vitamin Synonyms 33 Differential Diagnosis 34 Dosing Tools 34 ACLS PALS Guidelines 35 Dobutamine amp Dopamine Dosing Calculators 35 Epinephrine Calculators Adult amp Pediatric 35 Heparin Dosing Calculator 35 IV Rate Calculator 35 Nitroglycerin Dosing Calculator 35 Nitroprusside Dosing Calculator 35 Norepinephrine Dosing Calculators Adult amp Pediatric 36 Drug Classifications 36 Antiarrhythmic Drug Classification 36 Cephalosporin Generations 36 Chemotherapy A Z 36 NSAID Classifications 36 Prostiglandin Synonyms 36 Drug Comparisons 36 ACE Inhibitors 37 Beta blocker Comparison 37 Calcium Antagonist Pharmacokinetics 37 Calcium Antagonists Pharmacology 37 Corticosteroid Potency Topical 37 Dopamine Agonists Parkinson s 37 NSAID Pharmacokinetics 37 Oral Antidiabetic Agents 38 Radiopaque Agents 38 Theophylline Content Salt Forms 37 Thyroid Equivalent Doses 37 Immunizations amp Prophylaxis 38 Contagious Diseases Incubation 39 Immunization Schedule Health Care Workers 38 Malaria Prophylaxis 38 Malaria Treatment 38 Tetanus Prophylaxis 38 Vaccine Injury Table 38 Laboratory Values 39 Anion Gap Calculator 39 Cerebrospinal Fluid Analysis 39 Cholesterol amp Triglycerides 39 Creatinine Clearance Calculator 39 Pheny
58. Committees e Assists when reviewing or presenting new drugs under consideration for inclusion in hospital formularies e Presents information on newly approved drugs to help increase the clinical and cost effectiveness of a facility s formulary e Provides timesaving concise reports describing formulary recommendations approved indications efficacy pharmacokinetics adverse effects and more Physicians Desk Reference PDR The electronic Physicians Desk Reference provides fast easy access to information found in the popular Physicians Desk Reference PDR the PDR for Nonprescription Drugs and Dietary Supplements and the PDR for Ophthalmic Medicines This integrated system 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS includes current FDA approved prescription drugs commonly used over the counter drugs and specialized ophthalmic pharmaceuticals Its global searching capability allows instant access to detailed data on ingredients drug interactions side effects recommended dosages clinical pharmacology pediatric use contraindications and available forms Information on drug manufacturers is also included What s in the Physicians Desk Reference The format and outline of the Physicians Desk Reference are identical to the familiar book version containing the following sections e Description e Actions clinical pharmacology e Indications e Contraindications e Warnin
59. Database will be searched 2 The more parameters you enter the more you will limit or pinpoint your search results When all known characteristics of the drug have been defined click the Search button 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Identify a Tablet Caplet or Capsule Imprint Code Side 1 LL Side 2 M Description Colors Shape CTRL click to Other E 7 Black DAAA lect z AE Hpk Blue Pattern All Patterns v Brown S IDENTIDEX System Drug Images Database search Imprint Code only search Imprint and or Description Search Clear If you have typed the wrong information and wish to begin again click the Clear button to remove all codes and characteristics and start over Search Path Drug Identification gt IDENTIDEX Showing Results 1 through 28 of 28 Imprint Trade Name Manufacturer Country AAPCC Poisindex Management s Mt LI Ledertrexate Lederle Laboratories Australia 077750 POISINDEX DOC239METHOTREXATE AND RELATED AGENTS LI M9 f United POISINDEX DOC246POTASSIUM SPARING DIURETICS Mazide saade Ladere kaparanes States 167802 POISINDEX DOC167DIURETICS LI M8 f United POISINDEX DOC246P OTASSIUM SPARING DIURETICS Mazide Ledere Laboratories States 167802 F oISINDEX DOC167DIURETICS LIM 12 Meclizine Hydrochloride Lederle Laboratories ate 003720 POISINDEX DOC
60. Documents Abilify ARIPIPRAZOLE POISINDEX Managements ARIPIPRAZOLE DRUGDEX Evaluations RX Aripiprazole 10 MG lactose monohydrate cornstarch microcrystalline cellulose Hydroxypropyl Cellulose Magnesium Stearate Ferric Oxide YELLOW AND RED Availability amp Manufacturing Availability Available Container Sizes Manufacturer Product ID AAPCC Code Registry Numbers Physical Description Imprint Form Color Shape United States Bottle of 30 unit dose package of 100 Bristol Myers Squibb P O Box 4500 Princeton NJ 08543 4500 Business Hours 609 897 6663 Fax Business Hours 800 321 1335 Drug Information 6383288 201122 NDC 591 48 0008 35 NDC 591 48 0008 13 R Imprint form color shape and A 008 10 slate Tablet pink Rectangle Images for NDC 59148 0008 35 Drugs Trade Generic Drug Lists 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES DRUG IDENTIFICATION Identify pharmaceutical tablets caplets and capsules by any of their characteristics such as shape color pattern or imprint code You can choose to search the IDENTIDEX System or the Drug Images Database from the Drugs tab the Drug Identification menu option The IDENTIDEX System returns detailed product information and provides a link to the POISINDEX Toxicologic Management for the drug Some of the detailed product information that can be included e Imprint C
61. Drug Allergy Drug Food Drug Ethanol Drug Tobacco Drug Lab Drug Disease Drug Pregnancy Drug Lactation 1 You can search a tradename generic name or alternative supplement Type the first drug brand or generic in the Enter Search Term field If you are unsure of the spelling just type as many characters as you know As you type the word wheel begins to narrow your search results in the Matching Drug Names list based on the characters you ve entered The more characters you type the more focused the results The number of matches to the drug name is also updated as you type 2 If the drug you are interested in is listed in the Matching Drug Names list click on the item and then click the button to add the drug to the Drugs to Check list or press the Enter key if the drug is shown highlighted in the Matching Drug Names column or double click the drug name 3 Repeat these steps until you have all the drugs you wish to check for interactions in the Drugs to Check list If you accidentally add a drug in the Drugs to Check list select the drug by clicking it then remove it from the list by clicking the button 2009 Thomson Reuters All rights reserved DRUG INTERACTIONS 4 Click the Add Allergies button to enter any drugs known to produce an allergic reaction in the patient Type the first few letters and watch the word wheel re position the list Keep typing until you see the drug
62. Emergency Medicine are selected by default To change the default search criteria check or uncheck the database checkboxes to reflect all of the databases you wish to search e Select all checkboxes within a main subscription type General versus Emergency Medicine by selecting the top General or Emergency Medicine checkbox e Quickly de select uncheck all databases by clicking the Uncheck All link Select check all databases by clicking the Check All link For an overview of each of the databases click the i information icon i to pop upa database definition Search checked databases Check All Uncheck All DISEASEDEX h Medicine 7 Summaries Gi C Clinical Reviews Li Clinical Reviews Li Emergency Medical Abstracts from Rick Bukata MD and Jerry Studies and Alerts Li Hoffman MD Li C PreHospital Care Protocols fi Summaries Li Exactly Match versus Begin With The default search method Find all keywords that Begin With uses the search term as the root term and expands on it You may also be familiar with the term wildcard search The Begin With search acts like a wildcard search with the expansion to the right of the search term You can override the default search method if you don t find the results you expect when performing an Begin With search Narrow and focus your search results using the Exactly Match search method The Exactly Match considers m
63. Enter Drug Names to Compare boxes 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES If you are not sure of the spelling enter at least the first few letters of each drug for the search e Click the Search button Change the Number of Drugs to Compare If you wish to add to the number of drugs to compare change the number maximum of 50 in the Show box and click the Entry Fields button The Compare Drug Summaries page will refresh with the number of boxes you requested Enter the tradename or generic drug name in each box and then click the Search button The matches to the drugs searched are shown to the right of the search term an Note Regardless of the number of drugs selected only two drugs can be displayed side by side for comparison at one time It is fast and easy to switch between drugs selected at any time using the dropdown box Wy Choose Specific Substances Compare Drug Summaries Enter Drug Names to Compare Choose Specific Substances Jamax AMOXICILLIN z penicillin PENICILLIN G POTASSIUM cipro l CIPROFLOXACIN x ketlex CEPHALEXIN HYDROCHLORIDE Search Clear Show fa Entry Fields Display Comparison If the search term you entered had several possible matches for example a search on amox yields results for both amoxapine amoxicillin and amoxicillin clavulanate potassium you will be asked to select a specific substance from the matches found
64. FFECTS SPIDER FUNNEL WEB LABORATOR YMONITORING TREATMENT OVERVIEW RANGE OF TOXICITY 0 0 OVERVIEW SUBSTANCES LIFE SUPPORT INCLUDED SYNONYMS CLINICAL EFFECTS THERAPEUTIC TOXIC CLASS SERED EE Buco entice LABORATORY MONITORING DESCRIPTION TREATMENT OVERVIEW GEOGRAPHICAL LOCATION RANGE OF TOXICITY CLINICAL EFFECTS SUMMARY OF EXPOSURE 0 1 LIFE SUPPORT aise ae A This overview assumes that basic life support measures have been instituted CARDIOVASCULAR RESPIRATORY 0 2 CLINICAL EFFECTS Outline Print Setup POISINDEX Manageme Pe esha 0 2 1 SUMMARY OF EXPOSURE Print Ready Select the Print Ready button or link when you wish to print the document in its entirety minus the outline navigation buttons and links The Print Ready option opens a new browser window with the document shown as a print preview Print by selecting the print option from your Internet browser menu Print Setup Select Print Setup when you want to print portions of the document The Print Setup link presents you with a selection page to allow you to choose which sections to include in the printout of the document Select the sections to include by clicking the checkbox beside the section name Quickly select or de select all by using the Check All or Uncheck All links as appropriate Print Preview View a preview of the document by clicking the Display button From the print preview page print the document by selecting the print
65. Facility wide access to trusted drug information e Improved searching and navigation 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Links to Healthcare Series for in depth research Medical Librarians e One comprehensive resource for clinical decision support e Consistent information throughout the entire hospital Miscellaneous Navigation Breadcrumbs my inor THOMSON _ MICROMEDEX Healthcare Series MICROMEDEX Drugs Toxicology Disease Labs 1V Compatibility Interactions Patient Ed Formulary Handheld PDA E Print Ready Ei Subscription Details Page Help Search Path f Main Keyword Search gt Initial Results gt Narrow Results gt Breadcrumb Document DRUGDEX Consults DRUG THERAPY OF OPIOID WITHDRAWAL PATIENT DATAIBACKGROUND Please review the therapy for narcotic withdrawal RESPONSE Drug therapy of narcotic dependence and associated withdrawal includes the use of alpha 2 receptor agonists to minimize withdrawal symptams medically supervised detoxification opioid antagonists and maintenance opioid replacement therapy Raisch et al 2002 The exact biochemical processes which underlie the production of tolerance physical dependence and the opiate withdrawal syndrome remain unclear L It is becoming more evident however that catecholamine involvement and more specifically the locus coeruleus a major noradrenergic nucleus in the brain are important for the de
66. Hispanic black or Hispanic had less than a high school education were younger than 75 years or did not have a chronic medical condition Authors note the lack of continuing increases in vaccination rates should cause concern and indicates that new approaches are needed References e LuPJ Singleton JA Rangel MC et al Influenza vaccination trends among adults 65 years or older in the United States 1989 2002 Arch Intern Med 2005 165 16 1849 1856 Available from URL http Jarchinte ama assn ora cai content abstract 1 65 16 1849 As accessed 9 23 05 e Studies show conclusions and describe the method used and results for the study e Alerts provide pertinent information on changes in protocols and or procedures for a subject Tests amp Procedures Test and Procedure documents available to all DISEASEDEX subscribers offer the clinician evidence based fully referenced information on administration interpretation of a test or procedure 2009 Thomson Reuters All rights reserved DISEASE INFORMATION Search Path Main Keyword Search gt Initial Results Your Search iv fluid Modify your search iv fluid i Find all keywords that Exactly Match Begin With GoTo Summaries Drugs Labs Drug Identification Summary Documents DISEASEDEX Tests and Procedures Intravenous fluid replacement Clinical Points Drug Information Titles amp Synonyms DEX Tradename List 4 Clinical Check
67. Information e Physical Description including drug images where available Search on a drug and view all of the generic and tradenames currently available for this drug You can also view who manufactures the drug and where All products include links to the detailed drug document for the drug searched Search for Trade or Generic Drug Names Search for drug name Aripiprazole DRUGDEX Products Martindale Products O MARTINDALE en Espa ol 1 Type all or part of the trade or generic drug name in the Search for Drug Name box The more specific your search term the more focused your search results In other words if you know the strength and or route include it in the search to eliminate extraneous search results 2 Select to search the DRUGDEX System Martindale or the Spanish Martindale database subscription is required for access to database by clicking the corresponding option button 3 Click the Search button to begin the search for the product information DRUGDEX vs MARTINDALE Note The DRUGDEX System contains drug data gathered from major drug centers and pharmacology services worldwide FDA approved and investigational drugs along with over the counter and non U S preparations are covered with regard to dosage pharmacokinetics cautions interactions clinical applications and comparative drug efficacy In addition to the basic information available on all products in DRUGDEX ex
68. L EFFECTS LEE SUPPORT LABORATORY MONITORING CLINICAL EFFECTS TREATMENT OVERVIEW RANGE OF TOXICITY r E T j LABORATORYMONITORING TREATMENT OVERVIEW THERAPEUTIC TOMC OLASS SPECIFIC SUBSTANCES BANGE OF ToneiTy o AVAILABLE FORMS SOURCES CLINICAL EFFECTS D1 LIFE SUPPORT SUMMARY OF A This overdew assumes Mat basic Me support measures have Deen instituted EXPOSURE VITAL SIGNS 0 2 CLIMICAL EFFECTS HEENT 021 SUMMARY OF DPOSURE A WITH POIBONINGIEXPOSURE 1 IRRITANT VS CORROSIVE Some substances may be irritating or corrosive GASTROINTESTINAL depending on the concentration motarity and other factors In general serous ACID DASE esophageal injury is associated with ingestion of products wan a pH of 11 5 or higher DERMATOLOGIC 2 CONCENTRATION AND DURATION OF CONTACT Necrosis may develop after oniy CARCINOGENICITY minutes of exposure and longer contact increases tho arva of necrosis Hower OTHER concentration levels are more important Dut aiso tissue dependent n POISINDEX Management 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION Discontinued Products Drano Foamer Granules Products that have been discontinued are shown in a grey row and are noted as Discontinued to the left of the product name Information can still be found for the product by clicking the appropriate link Non US Products There may be times when the same search term yields results for
69. NC or ICD 9 Codes cceeeeeseeeeteeeteeees 96 Full Text Searches within Document SECTIONS ooo eee ccccscccssseceesseeesseseecsseeecesseeserssaeeenseees 96 Search oy Healthcare Category sesseur E EELEE butions 96 Sp ciiic D tabase Scar oee errenneren Ere nE aa EEA e EE E SEEE OEE E EEEE 97 Search Options in the Database Search ooo cece ccccscccssceccsssecessseeeeseccnseseecsseeescssseeenseesenaes 97 GVW ONG cas E E T T E A AT OAN AAE E E E A ATE AAT 97 Signs and SYMPTOM Seii douhanncsiaanchiansndeehaahunanaiaaasaonees nda E eao e iaia 97 LOINC Codes Logical Observation Identifiers Names and Codes c ccccccsececsesesessecessesteescseecssseeesseseeees 97 CD 9 C Ode Sera E E A E E E T E E E tee 97 Create a Specific Disease Database S arch cccccccccsccccssscccssesecesseeesesseecseeeeessseesenseesenaes 97 Default Search Summary Documents Only vecsvevcczersaccesscecasesensasaadeneaecdvavevericesudasacesaesensseies 98 Databases included in the Disease Specific Database Search 100 Browse Disease Categories ecerniroiiissiitisss sste enee ERE EEKE EEA EREEREER aT 102 SPSCIIG TOPIC SEANG Meseria E r N N E T A N E 103 Chapter 6 Labs s sniscsisssenicsesscsceoseisensceseinsussrcesaros ro ouarene rse sedae edos eaaeo a oes 109 Salhi Spedice Data DaS E srei ir arene E ENEE E I R R AE R TIO SANG MOY Lest IN AMC eee ere erra e E E AE E E EE ETE E EE EE TIO Searc MEy DUGNI E eeoa E A meen CINDY E E ATA 112 Search by Indication Or CONCItI
70. OINC Codes e Related Information e References Some documents will have only a subset of the above outline sections If no data or information is available for a section the outline title is not displayed If you wish to turn off the side by side outline and document display click the Outline link located at the top of the page This will present you with a page showing only the outline of the current lab document All sections are available by clicking the outline section name which will again open the document with the outline on the left Outline Sections with a Outline sections displaying a sign to the left of the outline section name contain a secondary outline section To display the secondary level click the section name displaying the sign Strength of Evidence In some lab documents a Strength of Evidence link is shown This provides the reader with a weighting that they can attach to the evidence shown The rating is organized into four categories Category A through Category C and No Evidence Click the link to view the definition of the category e Category A evidence is based on data derived from Meta analyses of randomized controlled trials with homogeneity with regard to the directions and degrees of results between individual studies Multiple well done randomized clinical trials involving large numbers of patients 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES
71. ON ccc eecccccccccecesscecsseseccsseeecssecccsseeceesseecsseceecsseeeseseeeenaes 113 Search by Panel NaMe orenen erinrar tE R EEEE EAE 113 Search by LOINC Code w ccccccccccccssccccsseccessseeceseeeccsseeecsseeescsseecesseeecesseseseseecseeeecseeecenseesenaes 114 BrOWSE THELIST OF NOSES rererere EEEE T EE E EE EREE E a enone 114 Printing Lt VIS Ot DOCUMEN S ssie a nen dienes ENEN R RS 116 SC AC VSO CEH FODE aeee EO E ETEA EEA 118 Chapter 7 IV COmpatitiuity xc ccccsccccssseccccrsaccaccseccorsessacecesessectenaeccatensseneacsecsousnets 119 Multiple Drug Sereias ee ennaa aE oee TEE TE n RENEA SAAE AEE SEEE Tg Compatibility Details srpnem dates lace lous E A E deals eup lade lvas deewed EEEE 122 Single Drug seale qmenenrae ene ren EEE ee ete eo EE TROT T ate oy ye eines 125 Chapter 8 Drug Interactions cccsssscccssseccsscccsssccccescccsssccnsscecesscesesees 135 Single and Multiple Drug Interactions oss siccstecasussussaussenxsusssstscurenansnsseswhetedinssiarnineantivedestieceseaes 135 Chapter 9 Patient Education cccsscsssccsseccesccnsccsseecesccsccsccescccesccesceees 141 thecareNotes SyStEni erate rae neu ne Ue ON DRR NER IER aE hte Me ee an EE STENT CVT rT oan ey ere am 141 Alternative Medicine Education oo ic ccccccccssscecsssceccsseeeeseeecessecccsaseecesueeecesseecssaeecessaeeetsseesenaes 141 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Chapter 10 Formulary am
72. OPLASMA PNEUMONIA 1 When only one document within a database is found as a match the document title name is displayed as a link Clicking the link will open the document 2 Results x When multiple documents within a database find a match to the keyword either in the title the synonym the index or as a related term i e Use in Comparison with Adult Dose etc the total number found is listed beside the 2009 Thomson Reuters All rights reserved Results link Click this link to open the Narrow Results page showing where the results were found Search Tradenames Search Products and not shown Search Imprint Codes clicking one of these links searches for the DRUGDEX tradename Martindale or POISINDEX product or IDENTIDEX imprint codes using the keyword entered previously Click the link to search specifically looking for tradenames products or imprint codes Search results are returned on a new page if a match is found Most results are displayed in a table format similar to the Tradename List page as shown below for a Martindale Related Products link Tradename List Search Result of Search Related Products for j Martindale from the Initial Results page Martindale Products Showing Results 1 through 1 of 1 Tradename List for pneurnonia Name Form amp Strength Contact Ommunal Altana Arq Altana Arg Altana Pharma SA Showing Results 1 through 1 of 1 Tradenames from
73. PDA Need training to access clinical information at the point of care FEW Print Ready Calculators Subscription Details Page Help Search Path Toxic Substance List Search gt IDENTIDEX Imprint List Showing Results 1 through 10 of 10 Imprint Trade Name Manufacturer Country AAPCC Poisindex Management s Mrk 951 Cozaar Merck United States 201079 ANGIOTENSIN IL ANTAGONISTS Mrk 951 Cozaar Merck Frosst Canada 201079 ANGIOTENSIN IL ANTAGONISTS Mrk 952 Cozaar Cozaar Merck United States 201079 ANGIOTENSIN II ANTAGONISTS Mrk 952 Cozaar Cozaar Merck Frosst Canada 201079 ANGIOTENSIN II ANTAGONISTS Mrk 960 Cozaar Merck United States 201079 ANGIOTENSIN II ANTAGONISTS Mrk 960 Cozaar Merck Frosst Canada 201079 ANGIOTENSIN II ANTAGONISTS Mrk 925 Fosamax Merck amp Company United States 077920 BISPHOSPHONATES Mrk 925 Fosamax Merck Frosst Canada 077920 BISPHOSPHONATES Mrk 936 Fosamax Merck amp Company United States 077920 BISPHOSPHONATES Fosamax Mrk 936 Fosamax Merck Frosst Canada 077920 BISPHOSPHONATES Showing Results 1 through 10 of 10 Imprint Code MRK 9 Search Results Click the trade name link to view the Product List From the Product List page you can e view pertinent formulation information e click the lt Previous or Next gt buttons to move to the previous next product in the list of results e click the links for toxicologic managements for this product
74. RSTANDING THE BASICS 9 Disease Labs IV Compatibi Specific Database Search Specific Topic Search Use the Disease tab to search for general and emergency disease treatment information or differential diagnosis information Labs IV Compatibility Int Specific Database Searc Specific Topic Search Use the Labs tab to search for assistance with interpreting and managing clinical laboratory test information The Lab Advisor database complements the DRUGDEX POISINDEX and DISEASEDEX databases with information specifying which lab tests are appropriate for a given condition and how lab test results can be interpreted IV Compatibility IV Compatibility Search IV Compatibility for fast easy to interpret answers to intravenous IV compatibility questions and for in depth study information Interactions I teractions Eas Use Interactions to calculate drug interactions for a single drug or a list of drugs Interactions results display drug drug drug food drug ethanol drug tobacco drug lab test drug pregnancy drug lactation ingredient duplication and drug allergy interaction information 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Patient Education Patient Ed CareNotes System AlttCareDex Alternative Medicine Education Print fully referenced patient education materials from the Patient Education tab Search the CareNotes System available by
75. SERIES PRINTING DOCUMENTS Four options are available for hard copy printouts of documents Select the best option for your needs Print from the Browser Use the Print function on your Browser to print the open document Buttons and links Breadcrumb Help button etc will be included in the printout using this method Print Ready Printing documents without Outlines To quickly print a document in its entirety select the Print Ready link A new window opens with your document formatted for print All extraneous navigation items buttons tabs links etc are removed from the document Print by selecting your Internet browser s print function e g File gt Print from this new window Close the window after completing the print dialog to return to the Healthcare Series application 2009 Thomson Reuters All rights reserved Documents with standard outlines also include the Print Setup feature Select the Print Setup link to print or display specific or non contiguous sections in the document After you select the Print Setup link you are presented with the Print Setup page Select the document sections you wish to view and or print For selected sections of a document e Click to select check the document outline sections you wish to view or print e Click the Display button e Anew window opens and the document is assembled with only the outline sections you selected e View the assembled document by sc
76. Search Path Main Keyword Search gt Initial Results gt Narrow Results gt DRUGDEX Drug Point Acetaminophen back to top DrugPoint Summary Acetaminophen see details in DRUGDEX Expand All Collapse All Dosing amp Indications Dosing amp Indications Dosing Information Adult Dosing Pediatric Dosing Adult Dosing see details in DRUGDEX Indications FDA Labeled Indications Non FDA Labeled Indications Contraindications Warnings Contraindications Precautions Pregnancy Category Breast Feeding Drug Interactions single Drug Drug Moderate Adverse Effects Common Serious Name Info US Trade Names Synonyms Class Dysmenorrhea 650 to 1000 mg ORALLY every 4 h as needed maximum 4 giday Dysmenorrhea 650 mg RECTALLY every 4 to 6 h maximum 6 suppositories 24 h Fever 650 to 1000 mg ORALLY every 4 h as needed maximum 4 g day Fever 650 mg RECTALLY every 4 to 6 h maximum 6 suppositories 24 h Headache 650 to 1000 mg ORALLY every 4 h as needed maximum 4 g day Headache 650 mg RECTALLY every 4 to 6 h maximum 6 suppositories 24 h Pain Mild to Moderate 650 to 1000 mg ORALLY every 4 h as needed maximum 4 g day Pain Mild to Moderate 650 mg RECTALLY every 4 to 6 h maximum 6 suppositories 24 h Pediatric Dosing see details in DRUGDEX Dysmenorrhea 10 to 15 mg kg dose ORALLY every 4 to 6 h maximum 5 doses day a Dysmenorrhea age 12 y and
77. Setup Trade Generic Drug List DRUGDEX Evaluations Expand All Collapse All Overview Dosing Information Drug Properties BUPROPION Storage and Stability Adult Dosage i Pediatric Dosage 0 Overview Pharmacokinetics 1 Class Onset and Duration a i Print Ready Select the Print Ready button or link when you wish to print the document in its entirety minus the outline navigation buttons and links The Print Ready option opens a new browser window with the document shown as a print preview Print by selecting the print option from your Internet browser menu Print Setup Select Print Setup when you want to print portions of the document The Print Setup link presents you with a selection page to allow you to choose which sections to include in the printout of the document Select the sections to include by clicking the checkbox beside the section name Quickly select or de select all by using the Check All or Uncheck All links as appropriate Print Preview View a preview of the document by clicking the Display button From the print preview page print the document by selecting the print option from your Internet browser menu For more print options and information on printing documents see Printing Documents on page 30 2009 Thomson Reuters All rights reserved DRUG INFORMATION THERAPEUTIC CLASSES Use the Therapeutic Classes search when you know you are searching for drugs within a therapeut
78. T H O M S ON REUTERS MICROMEDEX HEALTHCARE SERIES USER GUIDE HEALTHCARE 2009 Thomson Reuters All rights reserved This manual as well as the data and software implementation described in it is furnished under license and may be used or copied only in accordance with the terms of such license The content of this manual is furnished for informational use only is subject to change without notice and should not be construed as a commitment on the part of Micromedex Except as permitted by such license no part of this publication may be reproduced stored in a retrieval system or transmitted in any form or by any means electronic mechanical recording or otherwise without the prior written permission of Micromedex The data and software implementation as with all technical and computer aided design software is a tool intended to be used by trained professionals only The data and the software implementation is not a substitute for the professional judgment of trained professionals The software implementation is intended to assist with product design and is not a substitute for independent testing of product stress safety and utility Thomson Reuters assumes no liability for any error or inaccuracies that may appear in this manual THOMSON REUTERS MAKES NO WARRANTIES WITH RESPECT TO THIS MANUAL AND DISCLAIMS ANY IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE MICROMEDEX Micromedex Health
79. UMMAE S sareen eiee e T E Ee EERE SEE E EE EEEE ESES 43 Trade Genere Wii is ninna A A T reer rer eee tere tye rence incre mre 47 OUT information FACIES sco ceeecnevichsn sbudasassaltacianeen sips E a E EE 48 Drug lde ntincatioNes precion er ER EEEE RRE EERE RE 50 Search Drug dentification IDENTIDEX SySte ni ogien aa 51 Search Drug Identification Drug Images Database cee ccccccccessseeseeeceeseeeeseseenseesseesecsseeseesseesaes 53 Specific Dat base searen a e e a ea EEEa denned 56 SOI TOPIC Seale Meore ereraa AE E EERE E EREE 59 Document Outline nyaran aa e E A E E E AEE 61 Print Setupand Print Oy eerror ainnean on aE EEA EEEE EAE EAEE E EEEE EEEE 62 Th rapeutie Clas SES erroia rE AA EEEE EEE E EEE 63 Chapter 4 Toxicology Information sssesssesssesoseessscosseeosesssecoseeosseosseooseeoseo 65 TOXICE S bpstance Lis ec Saree a eiee EEEE E E E 65 Types of Toxic Substance Searches Available 0 cccccccccsecsseeceseeeseecsseeecseeseeeenseenseeesseeens 66 Productor SUBSTANCO sireenit nn rea eE EAHA EE EEEa EEE ENA NEE ov ETE ER AATE REESE 66 iganen aE ee e A AE EA A A A A E 67 A tive Ingredient ANG CodESisssrisriroisriscsiiesrirniieieisi i iii eee Eaa E EEEE S EEEE EA 68 Product IDs a EE ASA AE E E EE E NRE 69 AAPCC C d LOOK UPierssesivissyniyk oinei uriy aevehesiceeedna a a aia eiA ei aea ONENERA EENEN S Na iE aee iae 69 TOXIC Substance Search RESUS nesini iiine pies E E EE ea a 70 Product OF Substance SearchiReSuUlt i s
80. a derived from Expert opinion or consensus Case reports or case series e No Evidence Strength of Recommendation In some documents a Strength of Recommendation link is shown This provides the reader with a weighting that they can attach to the recommendation in the document The rating is organized into five classes Class lla IIb Ill and Class Indeterminant Click the link to view the definition of the class e Class Recommended The given test or treatment has been proven to be useful and is indicated in all cases 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Class lla Recommended In Most Cases The given test or treatment is generally considered to be useful and is indicated in most but not all cases e Class llb Recommended In Some Cases The given test or treatment is not generally considered to be useful It may be indicated in some but not most cases e Class Ill Not Recommended The given test or treatment has been proven to be harmful and should be avoided in all cases e Class Indeterminant Evidence Inconclusive 2009 Thomson Reuters All rights reserved DRUG INFORMATION SPECIFIC TOPIC SEARCH Use the Specific Topic Search to perform a full text search within specific outline sections of drug information documents Drug databases available for a Specific Topic Search are e DRUGDEX Drug Evaluations e Physicians Desk Refer
81. a five column table e The first column contains the drug name the concentration and the manufacturer s name e The second column shows the solution name and manufacturer s name e The third column lists the compatibility icon and description e The fourth column displays the physical compatibility chemical stability if applicable and storage information e The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination e Notes for the test if applicable are shown in red text at the top of the detailed study information In cases where the drug was not tested with the solution listed Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Solution Overview tab name link 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Search Path IV Single Compatibility gt Compatibility Overview gt Compatibility Details Modify Your Search Nitroglycerin more details Solution Detail Nitroglycerin D5W Dextrose 5 0 01 mgimL 10 megimL B Braun Notes Nitroglycerin will undergo substantial loss from aqueous solutions due to sorption to polyvinyl chloride PYC containers and administration sets Loss due to sorption does not occur to other common types of container and set materials such as glass and Pohl Boskamp polyolefin plastics x Physical Referen
82. ab Advisor documents include section outlines to aid in fast navigation throughout the document See The Lab Advisor Document Outline on page 115 for more information Print the document See Printing Lab Advisor Documents on page 116 Search by Panel Name Often standard testing procedures for a suspected diagnosis dictate that several tests be performed This is also known as a test panel If you know the panel name renal panel oarathyroid panel transplant panel for example but need to find information on any of the individual tests included search by the panel name 1 Verify that Keyword is the option selected in the Search for listbox 2 Type the common panel name in the text box If you are unsure of exact spelling change the selection from Exactly Match to Begin With and type the first few letters of the drug name 3 Click the Search button For example if you searched on transplant panel using this method Lab Advisor finds and displays many tests on the Narrow Results page Click on any lab test name link to view the individual lab document Lab Advisor documents include section outlines to aid in fast navigation throughout the document See The Lab Advisor Document Outline on page 115 for more information 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Print the document See Printing Lab Advisor Documents on page 11
83. abase Search gt Initial Results gt Narrow Results Search term renal failure DISEASEDEX General Medicine Summary Best Matches Titles 4 results Acute renal failure Acute Chronic renal failure Acute Chronic renal failure Chronic Chronic renal failure Prevention amp Screening 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 1 Acute most often are emergency or immediate care presentations but are available to both the Emergency and General Medicine subscription 2 Chronic on going health conditions and issues available to DISEASEDEX General Medicine subscribers only 3 Prevention amp Screening available to DISEASEDEX General Medicine subscription Prevention amp Screening ClinicalPoints and Clinical Review documents contain relevant assessment and screening information Acute Chronic and Prevention and Screening document types present information focused on a specific phase of illness All three types are available in both ClinicalPoints and Clinical Review format Studies amp Alerts Subscribers to DISEASEDEX General Medicine see links to Studies and Alerts found for the topic searched All Studies and Alerts documents are fully referenced Search Path Disease Database Search gt Initial Results gt Narrow Results gt Document DISEASEDEX Studies and Alerts September 12 2005 Study Trends in influenza vaccination coverage amo
84. abdomyolysis nsion Epidemiology Hypertension 3 Injury Etiology Pathophysiology frimune Globulin use History and Physical Abdominal compartment syndrome Summary NSAID use Medical History Sepsis Findings Diagnostic Testing Diagnostic Testing Summary e Tests Diagnosis Differential Diagnosis Treatment Treatment Summary Drug Therapy Findings show details Cardiovascular Hypotension Chest pain Procedural Thera Puleue paradors py Pericardial friction rub Prognosis Increased blood pressure Disposition Diastolic murmur Admission Consultation Discharge Follow up Related Information Conditions Tests amp Procedures Drugs Reference Dermatologic Pruritus Pallor Peripheral edema Ecchymosis back to top Delayed healing surgical wound The floating outline on the left side of the page allows for fast navigation to a desired point in the Clinical Review document Links within the Clinical Review documents such as Show details in the example above open the second level information for this section for this topic Search Path Disease Database Search gt Initial Results gt Narrow Results gt Document gt Details DISEASEDEX General Medicine Clinical Reviews Acute renal failure Acute Second Level Medical History Information Diabetes mellitus n Diabetes mellitus increases the risk of acute renal failure secondary to
85. acters Searches on just a few letters produce longer lists of possible matches Therefore type as much as you know about the drug to narrow the list as much as possible 3 When you see the drug in the Jump to drugs list select it by clicking on the drug and then click the Add gt gt button to place it in the list on the right Search Path IV Muttiple Compatibility O Multiple Drug Search Single Drug Search Search term war 0 Check Compatibility Clear Jump to drugs Vitamin B complex Amoxicillin sodium Vitamin B complex with C Cefazolin sodium VM 26 Voriconazole Voveran Voltaren Voltarol Panamor others Remove VP 16 213 arene Vumon Warfarin sodium 4 Type and select the second drug you wish to check At least two drugs must be selected to check IV compatibility from the Multiple Drug Search tab 5 Repeat until all drugs have been entered You can enter up to a total of 50 drugs in the list 6 Click the Check Compatibility button To remove a single drug from the list of drugs to search Click the drug then click the lt lt Remove button To remove all drugs from the multiple drug search Click the Clear button To check Single Drug compatibility Click the Single Drug Search tab link 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Compatibility Overview Breadcrumb Search Path IV Multiple Compatibility
86. akes it easy for the clinician to find the information they need as quickly as possible We hope you find the user interface logical the layout complementary to your workflow and that moving through the application is intuitive THOMSON MICROMEDEX Healthcare Series djia Drugs Toxicology Disease Labs IV Compatibility Interactions Patient Ed Formulary Handheld PDA a Calculators Subscription Details Page Help Search Path Main Keyword Search Main Keyword Search Search Drug Toxicology Disease and Labs databases for OOO Lesenreh_ C Search summary documents only Find all keywords that Exactly Match End in an asterisk Wliah aceta for Begin With search Begin with Select Databases ANATOMY OF THE HEALTHCARE SERIES PAGES The first page you see after you sign on to the Micromedex Healthcare Series is the Main gt Keyword Search page also known as the Home page A keyword search from the Main tab searches for your information across the drug toxicology disease and labs information categories You will only see the products and databases to which you subscribe To keep navigation as simple as possible the Micromedex Healthcare Series application suppresses hides from view any products or databases not subscribed to by the customer This removes extraneous text graphics and options from your view For a full listing of the products offered in Micromedex Healthcare Series organized by subscribed an
87. al parenteral nutrition is shown in the first table followed by TNA 3 in 1 total nutritive admixture compatibility Jump to the TNA 3 in 1 table by clicking the Go to TNA 3 in 1 results link an Note TPN and TNA results are not result type specific They can be a Y Site solution or admixture result Results are comprised of all compatibility tests where the drug name searched is either the primary or secondary agent and the drug is being included with a TPN or TNA solution Wy Within each TPN TNA table the results are sorted alphabetically by TPN or TNA admixture name with the associated compatibility icon and description followed by high level notes including composition of the TPN TNA on these tests Click the admixture name link to view the details of these tests Search Path IV Single Compatibility gt Compatibility Overview Modify Your search NitroglyCerin more details TPN 2 in 1 Goto TNA 3 in 1 results Aminosynil Notes Compatible Two TPN formulas peripheral line and central line formulas based on Aminosyn Il were evaluated for compatibility with the test drug 1 The peripheral line formula had the following composition per liter Aminosyn Il 3 5 Dextrose 5 Sterile water for injection 517 mL Sodium chloride 25 mEq Potassium chloride 35 mEq Potassium phosphates 3 5 mmol Magnesium sulfate 8 mEq Calcium gluconate 9 3 mEq MVI 1210mL Trace elements 2 The centra
88. and click the Go button The resulting report can be viewed or printed for your records or reference Dietary Considerations and Guidelines 4 w Vitamin Synonyms Vitamin K 1 Content of Foods Potassium Content of Foods Low Potassium Content of Foods High Caffeine Content of Foods Tyramine Containing Foods Lactose Content of Foods Calcium Content of Foods Iron Content of Foods lon Content K Ca Fe Salts Vitamin Synonyms Provides synonyms for vitamin names Vitamin K 1 Content of Foods Shows the food type and the content of mcg 100mg of those foods Potassium Content of Foods Low 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Lists foods low in potassium content Potassium Content of Foods High Lists foods high in potassium content Caffeine Content of Foods Lists foods and portion sizes that contain caffeine in mg Tyramine Containing Foods Lists foods that contain tyramine Lactose Content of Foods Lists selected milk products and their lactose content in grams per serving size Calcium Content of Foods Lists foods that contain calcium in mg per portion size Iron Content of Foods Lists foods with iron in mg per portion size lon Content K Ca Fe Salts Displays the element ion content of potassium calcium and iron salts with the percent of the element and the mEq associated with it Differential Diagnosis Most of these tools simpl
89. and efficacy e Information on species uses doses pharmacological actions side effects toxicity contraindications warnings and references e Quick and easy access to information IDENTIDEX System Tablet amp Capsule Identification The IDENTIDEX database identifies pharmaceutical tablets and capsules by imprint code and secondary characteristics such as color and shape Prescription and over the counter drugs both trademarked and generic are listed along with manufacturers telephone numbers and logo descriptions Many international and street drugs are included as is an extensive index of drug related slang terms What s in IDENTIDEX IDENTIDEX identifies substances from unmarked containers in emergency situations It includes prescription and nonprescription drugs with information about the manufacturer and provides an extensive library of information on street drugs and slang terms IDENTIDEX documents follows this standard outline e Imprint code Color e Dosage form e Active ingredients e Manufacturer e AAPCC code 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS Index Nominum from the Swiss Pharmaceutical Society Recognized worldwide Index Nominum is an international drug directory providing access to over 5 300 substances and derivatives more than 12 800 synonyms and over 41 800 tradenames from more than 45 countries The Thomson Reuters version of Index Nominum in Healthcare S
90. and should be avoided in all cases e Class Indeterminant Evidence Inconclusive References All Lab Advisor documents are fully referenced and include links within the document to the cited reference Links are displayed with the reference number Printing Lab Advisor Documents There are two options for printing lab documents Print Setup and Print Ready Print Setup Use the Print Setup link when you want to print a partial lab document The Print Setup page allows you to select the specific sections you want to include on the print out 1 Click the Print Setup link at the top of the document 2 Select the sections you want to include on the printed document by clicking the corresponding checkbox es Select Uncheck AIF then select the sections you want if only a few sections should be included Select Check All if you decide to print the entire document 3 Click the Display button The outline all buttons tabs and navigation links are removed from the document 2009 Thomson Reuters All rights reserved 4 Select File gt Print from your Internet browser menu Search Path Lab Keyword Search gt Document gt Print Setup Display CheckAll Uncheck All O Synonyms C Reference Range Indications M Common Panels Cl Abnormal Results Collection Storage Information Ml Test Definition C Reference Display Print Ready Use the Print Ready link when you want to prin
91. and the search results do not answer your question you can start an entirely new search directly from the Initial Results page Your Search fever Modify your search OR Did you mean cardioactive Search FEVER Search Find all keywords that Exactly Match Begin With Begin a new search by typing a new keyword in the Modify your search box and then clicking the Search button Documents Once you open a document you can Scroll through and read the relevant sections e Click cross reference links to learn more e Click outline section titles to jump to another location in the document e Click the outline link to view and navigate the full document outline e Click the Trade Generic Drug List link if shown to view product information e Print the document via the Print Ready or Print Setup links or the File gt Print menu option from your Internet browser e Use the Find function on your browser to locate a specific term or phrase in the document e Use the breadcrumb links to jump to previous page or location Floating Document Outlines Document outlines allow for faster information retrieval After performing a search and selecting a document from the search results page some documents display a document outline This outline will float along the page as you move through the document so it is always available for your use The outline divides a document into smaller sections cov
92. ange to enable appropriate triage of lab test results e provide information on how to interpret unfamiliar tests when evaluating patients e provide information on how to collect samples and submit tests Additionally administrators will soon have the ability to customize Lab Advisor by adding facility specific notes directly to the content Administrators will be able to attach notes to either the main title level or to a specific section within an individual lab document Notes will allow the hospital to communicate specific instructions and lab protocols directly within the content helping to increase compliance with the hospital s policies and procedures Notes will also be included in a download from Lab Advisor to users PDAs personal digital assistants once the user synchronizes the device Lab documents will include e test definition e test title synonyms e test methodology e reference range normal and therapeutic range e indications e list of drugs which could cause a drug lab interaction e collection storage guidelines e LOINC codes 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS e frequency and timing of monitoring for tests e panel information e abnormal results e test complications e customizable notes MARTINDALE The Complete Drug Reference This electronic version of the highly respected MARTINDALE reference book published by The Pharmaceutical Press offers extensive unbiased
93. arches will search the title and associated synonyms for a match to your search term s So a search on the synonym Bird Flu will find a match to the document titled Avian Influenza Signs and Symptoms Using the Signs and Symptoms search can be a useful tool to aid in diagnoses Search by the symptom vertigo for example and you will see that at least seven conditions may have vertigo listed as a sign or symptom LOINC Codes Logical Observation Identifiers Names and Codes LOINC Codes must be entered in the search term field in the following format 1 5 digits followed by a dash and ending with a single digit For example 32354 3 or 11271 4 ICD 9 Codes ICD 9 Codes International Classification of Diseases Codes can be searched in any of the three available formats ICD 9 CM 3 digits may also include a decimal point and up to 2 digits V Codes V followed by 2 digits may also include a decimal point and up to 2 digits E Codes E followed by 3 digits may also include a decimal point and one digit Create a Specific Disease Database Search 1 Type the complete disease symptom or substance 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2 Select the database s you wish to include in the search or leave the default Summary only search method 3 Click the Search button Default Search Summary Documents Only Only the Summary databases DISEASEDEX General Medicine amp
94. are shown only if you have a current subscription to these products 2009 Thomson Reuters All rights reserved DISEASE INFORMATION e JCAHO Joint Commission on Accreditation of Healthcare Organizations Related Information Conditions Aortic dissection Acute jal fi n Atrial fibrillation Acute Atrial fibrillation Acute Atrial fibrillation Chronic Atrial fibrillation Chronic Bradyarrhythmia Acute Bradyarrhythmia Acute Cardiac arrest Acute Cardiogenic shock Acute Cardiogenic shock Acute Cor rome acute Ac Diabetes mellitus Chronic Diabetes mellitus Chronic Diabetes mellitus Prevention amp Screening Diabetes mellitus Prevention amp Screening Paroxysmal supraventricular tachycardia Acute Paroxysmal supraventricular tachycardia Chronic Paroxysmal supraventricular tachycardia Chronic Pulmon lism Pulmonary embolism Acute Respi A Ventricular tachycardia Acute Ventricular tachycardia Acute WolftParkinson White syndrome Acute Wolff Parkinson White syndrome Chronic WolftParkinson White syndrome Chronic 000000000000000000000000000000 Tests amp Procedures Advanced cardiac life support i Blood urea nitrogen measurement Creatine kinase MB isoenzymertotal creatine kinase ratio measurement Creatine kinase MB measurement Creatinine measurement serum International normalized ratio Magnesium measurement serum Platelet count i White blood cell count
95. arrow and focus your search results using the Exactly Match search method The Exactly Match considers matches only where the search term s exactly match a title synonym or index term character by character Drug Database Search Search Drug Databases for carbaz Search Find all keywords that Exactly Match Erd in an asterisk iabt aceta for Begin With search Begin With Search checked databases CheckAll Uncheck All DRUGDEX System Li Index Nominum i MARTINDALE Li P amp T QUIK Reports E pore i Detailed Drug Information for the Consumer Alternative Medicine O REPRORISK System Li Summary Documents fi 2009 Thomson Reuters All rights reserved DRUG INFORMATION For example if you search on the term carbaz with Find all keywords that Begin With selected the Healthcare Series application finds the following related index terms carbazene carbazine carbazep carbazilquinone carbazochromum and several more All of the documents listed on the various search results pages contain one or more of these indexed terms Note Any change you make to the Exactly Match or Begin With search parameter is maintained for the duration of your Micromedex Healthcare Series session A session is active until you 1 Logout and 2 Close the browser window gt 7 Wy Search results for the databases selected are organized by c
96. ary Handheld PDA EEJ Print Ready E calculators ag Subscription Details Page Help word Search gt Initial Results gt Narrow Results Warfarin DRUGDEX Evaluations Results Titles 1 results Matches on a keyword in a document title are always y i listed first followed by Synonyms Related Terms DRUGDEX Evaluations Related Terms warfarin is in DRUGDEX Evaluations under these topics adverse reactions 1 results dose adult 1 results dose pediatric 1 results indications non FDA labeled 3 results interaction 317 results Like Go To links click a link here to go directly to that section adverse reactions 1 results back to top WARFARIN dose adult 1 results back to top WARFARIN dose pediatric 1 results back to top WARFARIN indications non FDA labeled 3 results back to top COENZYME Q10 EPOPROSTENOL WARFARIN interaction 317 results back to top ABCIXIMAB ACARBOSE ACEMETACIN ACENOCOUMAROL ACETAMINOPHEN keyword in areas of the document other than title synonym or indexed keyword Some examples of related terms are 2 adverse reactions e dosing adult amp pediatric e indications FDA labeled amp non FDA labeled e comparison with e interaction e asseenin e complication of e therapy of e andsoon 2009 Thomson Reuters All rights reserved Modify Your Search If you complete a keyword search
97. ass name hyperlink to the right of the closed folder icon to view the full list of drugs for the subclass A dashed line means there are no further subclasses Click the link to display the drugs for this therapeutic class 1 Click the closed folder icon to list subclasses within the current folder then click the link of a class displayed or Click the class name hypertext link to view the drug list for all drugs in that class 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2 The Therapeutic Class Drug List page displays listing all drugs within the selected subclass 3 View summary drug information by clicking the drug name hypertext link or Select the drugs that you would like to compare side by side See Compare Drug Summaries on page 43 for more information Go To GoTo os A BICIDIElFIGIHIIsIKILIMIN OlPlalRis Tlulyiwlixl ylz The Go To speed menu allows you to navigate quickly to another position in the alphabetical list For example click on the letter M from the Therapeutic Class page and the therapeutic class Musculoskeletal Agent is shown at the top of the page Therapeutic Class Drug List Search Path Therapeutic Classes gt Therapeutic Class Drug List Class Showing Central Nervous System Agent gt Antianxiety Choose drugs to compare or click on a name to view summary Compare Selected Drugs GoTo os AIBICIDIElFIGIHI i sIKILIMIn OlPlalri
98. atches only where the search term s exactly match a title synonym or index term character by character Note Note Any change you make to the Exactly Match or Begin With search parameter is maintained for the duration of your Micromedex Healthcare Series session A session is active until you 1 Logout and 2 Close the browser window we RA W 2009 Thomson Reuters All rights reserved DISEASE INFORMATION Initial Results The Initial Results page is displayed if matches were found for more than one database Results are organized by database name and content type below general categories Summaries Disease and so on The hypertext link to the right of the database name provides information on the type of information available It is important to remember that the search criteria used will determine the search results shown on the Initial Results page For example a search on the term diabetes using the default selection Summary documents only will result in Initial Results with links to the Summary databases only Search Path Disease Database Search gt Initial Results Your Search diabetes Modify your search OR Did you mean DIABETES v _Search_ diabetes Find all keywords that Exactly Match Begin With Go To Summaries Tiles amp Synonyms DISEASEDEX General Medicine Results 2 Summary DISEASEDEX Emergency Medicine Diabetic ketoacidos
99. ation about each of the databases see Appendix A Database Descriptions 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES BROWSE DISEASE CATEGORIES Quickly browse the full list of titles available to a specific healthcare category Disease Categories Browse Browse Under ORTHOPEDICS Jump to Humerus shaft fracture Acute ten Knee dislocation Acute Low back pain Acute Low back pain Chronic Nursemaid s elbow Acute Patellar dislocation Acute Pelvic fracture Acute Septic arthritis Acute Shoulder dislocation Acute e Select the healthcare category by clicking the down arrow on the Browse Under dropdown and clicking the desired category Click the Select button to the right of the dropdown this will populate the list of titles available for that category Either begin typing the first few letters of the title in the Jump to field to position the list at that point or use the horizontal scrollbar to move up and down in the list of titles Open the document by either clicking the title then click the Select button located to the right of the list or by double clicking the title name 2009 Thomson Reuters All rights reserved DISEASE INFORMATION SPECIFIC TOPIC SEARCH Use the Specific Topic Search to perform a full text search within specific sections of DISEASEDEX General or Emergency Medicine
100. care Series AfterCare Instructions Database AltCareDex System AltMed Dex System AltMedDex Points System AltMed REAX System CareNotes System Clinical Xpert System ClinicalPoints System Current Concepts Program DISEASEDEX System DISEASEDEX General Medicine DISEASEDEX Emergency Medicine DRUGDEX System DrugPoints System DRUG REAX System Formulary Advisor HAZARDTEXT Hazard Managements IDENTIDEX System IV INDEX System Lab Advisor MEDITEXT Medical Managements mobileMICROMEDEX System Physicians Desk Reference PDR P amp T QUIK Reports POISINDEX System REPRORISK System REPROTEXT Database TOM ES System and ToxPoints System are trademarks of Thomson Reuters All other trademarks are the property of their respective owner U S Government Customers The Products are provided to the Federal government and its agency with RESTRICTED RIGHTS USE DUPLICATION OR DISCLOSURE BY THE GOVERNMENT IS SUBJECT TO RESTRICTIONS SET FORTH IN SUB PARAGRAPH c 1 ii OF THE RIGHTS IN TECHNICAL DATA AND COMPUTER SOFTWARE CLAUSE AT DFARS 252 227 7013 OR SUB PARAGRAPHS c 1 O R 2 OF THE COMMERCIAL COMPUTER SOFTWARE RESTRICTED RIGHTS AT 48 CFR 52 227 19 AS APPLICABLE CONTRACTOR MANUFACTURER IS Micromedex 6200 S Syracuse Way Suite 300 Greenwood Village Colorado 80111 4740 USA TABLE OF CONTENTS VIC FOCUCTION voc eeececccccccccecceescessesseecseeeeceeecececce
101. care facilities throughout the world Ultimately our efforts will transform static data into proactive patient specific solutions For more information about Thomson Reuters please visit www micromedex com about_us 2009 Thomson Reuters All rights reserved INTRODUCTION 3 HOW TO CONTACT THOMSON REUTERS Corporate Office 777 East Eisenhower Parkway Ann Arbor MI 48108 USA Colorado Office 6200 South Syracuse Way Suite 300 Greenwood Village CO 80111 4740 USA Customer Technical Support www micromedex com support request Web site www micromedex com United States amp Canada Phone 1 877 843 6796 Speak the product name and select the Support menu option Fax 303 486 6450 Outside the United States amp Canada Phone 1 651 244 4000 Fax 303 486 6450 For more information on our products and services visit our Web site at http www micromedex com or contact your local distributor Customer or Technical Support www micromedex com support request 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES What is Micromedex Healthcare Series A trusted reliable clinical reference and decision support tool available to clinicians at the point of care The Micromedex Healthcare Series application ensures medical professionals have easy access to the most current clinical information available Recognized worldwide the Micromedex Healthcare Series is considere
102. ce 2289 compat Compatibility Physically compatible No visible Study Period 24 hours haze or particulate formation color change Method Visual or gas evolution observation and HPLC analysis of drug Storage Refrigerated at concentrations 4 C and at room temperature of 22 C Container Polyethylene protected from light B Braun plastic containers and glass B Braun containers Y Site Details Y Site compatibility details for single drug compatibility searches are shown in a five column table e The first column contains the drug name the concentration and the manufacturer s name e The second column shows the secondary agent name concentration and manufacturer s name e The third column lists the compatibility icon and description e The fourth column displays the physical compatibility chemical stability if applicable and storage information e The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination e Notes for the test if applicable are shown in red text at the top of the detailed study information In cases where the drug was not tested with the solution listed Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Y Site Overview tab name link Admixture Details Admixture compatibility details for single drug compa
103. ches for phenedrine phenelzine phenephrin phenerbel phenergan phenetron phenex and phenexpect you may wish to refine your search to view a more specific drug list If more than one page of results are found navigate to additional pages using the page number or First Previous Next and Last links DRUGDEX Tradename List Showing Results 151 through 200 of 305 Searching on the name form and strength e g Abilify 10mg or Abilify tablet will eliminate extra product links and pinpoint your specific search results Product Information Page Once you find the drug you want click the link to view the product information From this page you can Scroll through and read the relevant sections e Click the Related Documents links for the detailed drug monographs 2009 Thomson Reuters All rights reserved DRUG INFORMATION e Click the lt Previous or Next gt buttons to view the products before or after the current product in the search results list e Print this product via the Print button or the Print browser toolbar See Printing Documents on page 30 for more information e Use the Find function on your browser to locate a specific term or phrase in the document e Use the breadcrumb links to go to a previous page Search Path Trade Generic Drug List gt Tradename List Search gt Document Related Documents Regulatory Status Ingredients Active Ingredient Excipients Related
104. cists nurses and physicians time and your facility money Click the Formulary Advisor link and follow the instructions on that page to go directly to your facility s formulary THOMSON CLINICAL XPERT HOMSON Clinical Aa pert Trusted evidence based information for your Palm OS or Pocket PC handheld device Much more than quick drug look ups Clinical Xpert powers your handheld device with a wealth of clinical knowledge from Thomson Reuters the industry s leading provider of evidence based decision support It s compatible with both Palm OS and Pocket PC s updated instantly at each sync with the latest information Your download gives you exclusive access to e disease information e laboratory test information Plus free access to information spanning e drugs e interactions e alternative medicine e toxicology e news amp alerts e calculators 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Available in Clinical Xpert e Drug information Searchable database of close to 3 000 drugs with concise details on generic names common trade names class dosage and adjustments for adults amp pediatrics administration monitoring how supplied indications FDA labeled and non FDA labeled contraindications precautions adverse effects common and serious drug interactions pregnancy category and breast feeding e Acute care information common emergency conditions
105. cology Lists the name of the drug the refractory period on the AV node the automaticity on the SA node the AV conduction heart rate contractibility cardiac output and peripheral vascular resistance Dopamine Agonists Parkinson s Compares in order selected physical characteristics pharmacokinetics dosing adverse events drug interactions and efficacy data for bromocriptine pergolide ropinirole and pramipexole 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Oral Antidiabetic Agents By agent lists the hypoglycemic effect with onset peak and duration in hours protein binding and elimination percentage and half life percentage Radiopaque Agents A list of causative agents Also denotes if the agent was or was not confirmed in vivo study if it is enteric coated and if the agent listed is trademarked Immunizations amp Prophylaxis Most of these tools simply require you to select the calculator or reference by name and click the Go button The resulting report can be viewed or printed for your records or reference See Printing Documents on page 30 for more information on printing iy Vaccine Injury Table Tetanus Prophylaxis Malaria Prophylaxis Immunization Schedule Health Care Workers Malaria Treatment Contagious Diseases Incubation Vaccine Injury Table The Vaccine Injury Table is a National Childhood Vaccine Table with definitions of vaccine side eff
106. contact Breathe fumes In the eyes MEDITEXT documents follow this standard outline e Overview e Substances included synonyms e Clinical effects e Medical surveillance Laboratory e Case reports e Treatment e Range of toxicity e Kinetics e Pharmacology Toxicology Standards Labels e Physicochemical e References e Author information HAZARDTEXT Hazard Managements The TOMES hazard information can help you understand the following issues related to environmental impact including how to implement emergency reaction to chemicals and their impact Fire Clean up Personal protection HAZARDTEXT also helps you manage chemicals safely in the workplace The Hazard Management documents follow this standard outline e Identification Synonyms e Clinical effects 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS e Medical treatment e Range of toxicity e Minimum lethal exposure e Maximum lethal exposure e Toxicity values e Standards and labels e Workplace standards e Environmental standards e Shipping regulations e Handling and storage e Personal protection e Summary e Respiratory protection e Protective clothing e Physical hazards e Fire hazard e Explosion hazard e Dust vapor hazard e Reactivity hazard e Evacuation procedures e Containment Disposal guidelines Environmental hazard management e Pollution hazard Environmental toxicity e Physical Chemical properties e Sampling and
107. d in e DISEASEDEX Clinical Review documents DISEASEDEX General Medicine clinical reviews enable clinicians to quickly reference the most current treatment of choice information at the point of care to help minimize errors prevent unnecessary tests and procedures reduce treatment costs and improve patient outcomes DISEASEDEX Emergency Medicine clinical reviews are written for the acute or emergency viewpoint to help clinicians quickly access current and crucial data organized by both condition and diagnosis e ToxPoints documents for brief highlights of clinical effect treatment and range of toxicity information e DrugPoints documents for high level information on dosing drug interactions adverse effects pregnancy warnings indications cautions therapeutic class and brand information e Lab Advisor which presents the most critical information about which laboratory tests are appropriate for a given condition interpretation and management of results normal ranges test methodology and other laboratory related information You still have the ability to conduct broader searches that will return matches on all of our disease information databases by including them in your search selections but the default search option focuses on the Summary information first Acute Chronic Prevention amp Screening documents The DISEASEDEX General Medicine content is divided into three types Search Path Disease Dat
108. d the standard of excellence in clinical healthcare information Its comprehensive authoritative databases are unsurpassed in scope and reliability Micromedex Healthcare Series is ideal for healthcare professionals needing unbiased referenced information about drugs toxicology diseases acute care patient education and alternative medicine Written by experts for experts the Thomson Reuters suite of decision support tools delivers the most thoroughly reviewed and evaluated information available Thomson Reuters provides timely access to trusted information helping clinicians enhance decisions reduce adverse events and promote best practices What is the Thomson Reuters Editorial Process Producing Quality Documents Delivering effective reliable information resources requires in depth research and examination to ensure accuracy appropriateness and usefulness Thomson Reuters unbiased evidence based information undergoes an extensive editorial process ensuring the most current and accurate data is presented The Thomson Reuters editorial staff represents a wide range of clinical specialties Evidence Based Unbiased Documents Written By Experts Thomson Reuters considers many factors when selecting subjects for inclusion in our databases Topics chosen for further research are based on literature review of the world s healthcare journals scientific journals medical journals customer requests clinical judgment and recommendat
109. d unsubscribed peruse the page behind the Subscription Details j sstserintion petal ICON OF hypertext link Basic navigation in the Healthcare Series is via the tab Tabs are located across the top and are named Main Drugs Toxicology Disease Labs IV Compatibility Interactions Patient Ed and Formulary and Handheld PDA Click on a tab name to open the page 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Tabs in Healthcare Series Drugs Toxicology Disease Labs IV Compatibility Interactions Patient Ed AUTES Handheld PDA Main Drugs 4 Toxicology Calculators Use Main Keyword Search for fast access to your information requests The Main Keyword Search looks for all documents containing indexed terms matching your keywords in selected drug disease and labs information databases Use Main Calculators for fast access to commonly used calculators dosing tools nomograms and clinical references Drugs Toxicology Disease Compare Drug Summaries Trade G ic Drug Lists Therapeutic Use the Drug tab to search for summary or detailed drug information to compare drugs side by side to search for drug information by therapeutic class or to identify drugs Toxicology Labs Search for toxicology treatment information clinical effects range of toxicity and more Look up a product name imprint code or slang term 2009 Thomson Reuters All rights reserved UNDE
110. e Formulary Advisor is ideal for e Formulary managers and administrators responsible for updating and communicating the most current formulary facility wide e Directors of pharmacy wanting to save time and increase efficiency of their pharmacies operations e P amp T Committees needing a convenient way to update information on the hospital formulary e Hospitals concerned with meeting their drug allocation budget e Healthcare professionals who prescribe order dispense or administer drugs Formulary Advisor e Facilitates and encourages formulary compliance with convenient point of care information 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Provides real time formulary updates e Helps you realize drug budget allocation cost savings e Easily identifies a drug s formulary status as determined by your facility s P amp T Committee e Furnishes a cost effective alternative to internally developed or vendor purchased systems Herbal Medicines A Guide for the Health Care Professional Herbal Medicine Information The electronic version of Herbal Medicines book published by the Pharmaceutical Press answers many questions raised by healthcare professionals and patients by providing factual information about herbal medicines As part of the Micromedex CAM complementary alternative medicine Series Herbal Medicines presents e 141 referenced monographs e Reliable information on safety
111. e document For more information on the Narrow Results page see Narrow Results on page 26 Refining Your Search Results If you complete a search and the search results include products or substances that do not apply to the information you desire you can choose a term from the list of possible matches and search again on just the selected term Your Search folic acid Modify your search OR Did you mean folic acid Search FOLIC For example A search on the keyword folic returns many results Isolate the Search Results to just folic by selecting the product from the OR did you mean drop down box and clicking the Search button 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Modify Your Search If you complete a specific database search and the results do not produce the information desired you can start an entirely new search directly from the Search Results page Your Search folic acid Modify your search OR Did you mean gt Search FOLIC gt Search Begin a new search by typing a new product or substance in the Modify your search box and then clicking the Search button Databases included in the Toxicology Specific Database Search e POISINDEX System Products and Managements e TOMES System which includes e MEDITEXT Medical Managements e HAZARDTEXT Hazard Managements INFOTEXT Documents e REPRORISK System which includes e
112. eae nucleic acid hybridization test Plasma glutamic acid level Serum methylmalonic acid level Serum uric acid measurement Uric acid measurement urine Urine methylmalonic acid level Synonyms 3 results Amino acids measurement quantitative urine Urine amino acid levels Enterovirus polymerase chain reaction Enterovirus ribonucleic acid detection Ham test Acid haemolysin assay Lab Advisor Related Terms acid is in Lab Advisor under these topics e brand names 4 results e drugilab interactions 1 results e indications 3 results brand names 4 results Aluminum measurement blood Mi Acid Digoxin measurement Acetic Acid Hydrocortisone Schilling test Folic Acid Vitamin B12 Urine methylmalonic acid level Amino Acid Complex drugiab interactions 1 results Direct Coombs test Clavulanic Acid indications 3 results Folic acid measurement RBC Folic acid deficiency Lysergic acid diethylamide measurement Lysergic acid diethylamide dependen Serum chloride measurement ofacid base balance Search by Drug Name Searching by a drug brand or generic name can help a clinician determine if a drug is causing or could cause a drug lab interaction 1 Verify that Keyword is the option selected in the Search for listbox 2 Type the drug name brand or generic in the text box If you are unsure of exact spelling change the selection fr
113. earched for the term by clicking the checkbox It may be faster to click Uncheck AIF to remove all checkmarks and then select the individual sections In our example only Collection Storage Information should be checked 3 Click the Search button to begin the search 4 lf only one document contains the search term in the specified section the lab document opens If multiple matches are found the Search Results page displays the lab test name as a link followed by a link on each section name where the search term was found A brief excerpt or sentence with the search term displayed in bold text is displayed beside each section to assist you with in determining the context of the search term in the section Lab Advisor documents include section outlines to aid in fast navigation throughout the document See The Lab Advisor Document Outline on page 115 for more information Print the document See Printing Lab Advisor Documents on page 116 2009 Thomson Reuters All rights reserved CHAPTER 7 IV COMPATIBILITY Use the IV Compatibility page to pinpoint potentially dangerous IV drug combinations When multiple IV medications are combined the risk of complication is very real Efficacy of one or more drugs can be reduced or a potentially dangerous incompatibility can occur The IV Compatibility page provides easy access to the IV INDEX System with proven data to assist with accurate IV compatibility decisions at
114. ects Lists the requirements for recording vaccines given Shows the vaccine name with an even associated with that vaccine and intervals from vaccination that these events were seen within Also includes general guidelines for these vaccines Tetanus Prophylaxis Shows general contraindications for the vaccine definitions associated with Tetanus and wound management related to a recipient of the vaccine less than and greater than seven years of age Malaria Prophylaxis Lists the drugs used in the prevention of Malaria Also shows the usage of those drugs and comments related to their use Displays dosing guidelines for both adult and pediatric patients Immunization Schedule Health Care Workers Provides recommendations for immunizations healthcare workers should have Lists common abbreviations recommended immunization agents recommended post exposure prophylaxis and information when a source is positive negative not tested or unknown to a specific communicable disease Malaria Treatment 2009 Thomson Reuters All rights reserved This tool details oral regimens for drug of choice treatments for adults and pediatrics Includes dosing parenteral regimens and notes related to malaria and treatment Contagious Diseases Incubation Lists the incubation and isolation periods for contagious diseases Includes the name of the disease the duration of the incubation period of communicability and the type of isolation re
115. ence e Martindale The Complete Drug Reference e AltMedDex Evaluations Search results show the document title the section and a snapshot of the text where the search terms were found You have the option of opening the document at the beginning click on the title link or opening the document directly at the specified outline section click the section name link Create a Specific Topic Search 1 On the Drugs tab select the Specific Topic Search menu item 2 Select the drug database you wish to search The available outline sections change as the database is selected 3 Type the exact term to search Typically the search term is a drug indication adverse reaction etc 4 Select the type of information you want from the available topic checkboxes The application searches the selected checked topics for information related to your keyword s All topics are selected by default To Uncheck all of the checkboxes click the Uncheck All link Once unchecked you can then select the topics you wish to search Drug Topic Search Choose One Database to Search DRUGDEX DRUG EVALUATIONS O MARTINDALE The Complete Drug Reference OPDR OALTMEDDEX Search document for this exact term buproprion Search Within Check All Uncheck All O overview Teratogenicity C Dosing Information Therapeutic Uses C Pharmacokinetics C Comparative Efficacy C Contraindications CI References CO Precautions
116. er Simulated Y site temperature exposedto administration using plastic fluorescent light multi well plates In cases where the drug was not tested with a listed drug Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Y Site Overview tab name link 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Admixture Details Admixture compatibility details for multiple drug compatibility searches are shown in a five column table The first column contains the drug name the concentration and the manufacturer s name The second column shows the secondary agent name concentration and manufacturer s name The third column lists the compatibility icon and description The fourth column displays the physical compatibility chemical stability if applicable and storage information The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination Notes for the test if applicable are shown in red text at the top of the detailed study information In cases where the drug was not tested with a listed drug Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Admixture Overview tab name link Syringe Details Syringe compatibility details for multiple drug compatibility
117. eraction may be life threatening and or require medical intervention to minimize or prevent serious adverse effects e Moderate the interaction may result in an exacerbation of the patient s condition and or require an alteration in therapy e Minor the interaction would have limited clinical effects Manifestations may include an increase in the frequency or severity of side effects but generally would not require a major alteration in therapy e Unknown unknown ETI Drugs Toxicology Disease Labs Mey Interactions J Patient Ed Formulary Handt EJ calculators Rig subse Search Path Check Interactions Multiple Drug Interactions Type the Drug Name brand or generic in the search field Select the drug and click the Add O Enter Search Term l ad Matching Drug Names 77 Drugs to Check Add Allergies spin ADC Vitamin Drops Warten ADC wiFluoride y ADC wiFluoride amp Iron Adacel Adagen Adalat Adalimumab Adapalene Adapin Adaptosode For Stress and capitalized indicates allergy Check Interactions 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Check Drug Interactions aad ko T Note For single drug interactions search on the individual drug For multiple interactions enter the full list of drugs Wt Note Interactions calculated include Drug Drug includes alternative medicines
118. eries edited by the Swiss Pharmaceutical Society provides electronic access to an international drug directory of generic substances drug tradenames synonyms chemical formulas therapeutic classes and manufacturer information Designed to meet the drug information needs of drug and poison information centers pharmacists physicians research and medical centers pharmaceutical companies and libraries the system presents area specific information from more than 45 countries for preparations used in human and veterinary medicine Index Nominum enables users to locate information by entering a substance name therapeutic category brand name synonym chemical name manufacturer name or country as the keyword or search term Each monograph provides detailed information about a drug s name and synonyms chemical structure diagrams and a list of manufacturers Name and address information enables the user to conveniently identify manufacturers worldwide Index Nominum contains e Drug tradenames e Official and unofficial synonyms e Substances and derivatives e Manufacturer names and addresses e Therapeutic classes e CAS numbers e ATC codes e Chemical structures e Molecular weights IV INDEX System e Features Trissel s 2 the latest database from the ultimate authority on IV compatibility Lawrence Trissel MS FASHP e Enhances patient safety by pinpointing potentially lethal combinations e Supports confident decisions with
119. ering specific topics or information The floating outline displays first and second level outline sections only For outlines with up to six levels of sections see Full Document Outlines below Click on the outline title of the relevant topic or information to go to that location in the document 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES DEXPANTHENOL back to top Expand All Collapse All Overview Dosing Information Drug Properties Storage and Stability Adult Dosage Pharmacokinetics ADME Cautions 2D eee ee DEXPANTHENOL Precautions E alka a back to top Adverse Reactions Clinical Applications Expand All Collapse All Monitoring Parameters F Place In Therapy Overview Mechanism of Action Dosing Information Pharmacology Pharmacokinetics Therapeutic Uses Comparative Efficacy Evaluation Cautions With Other Therapies Clinical Applications References References Floating outline Expanded Floating outline Collapsed Document Outlines with or Some outline section titles will be preceded by the or symbol The minus sign means that all sections below the top level are visible See dexpanthenol example above left The plus sign means that there are additional levels of outline sections below the current level but they are not currently visible See dexpanthenol example above right To move to and view t
120. es Database Information that can be displayed from the Drug Images data e Drug Name Generic Ingredients e Imprint Code e Color Shape Form Route e NDC Code e Image Search Path Drug Identification gt Drug Identification Results gt Drug Identification Details Search POISINDEX Toxic Substance List for this Drug Name _ Search Drug Identification Chlorzoxazone Drug Name Chlorzoxazone Jump toithe DENTIDEX System Ingredients Chlorzoxazone 500 MG wath the Search butian NDC 00555 0585 02 Color Green Imprint 555 585 BARR Shape Circle Form Tablet Route Oral route Drug Image Search Drug Identification IDENTIDEX System 1 Enter the descriptive information in the appropriate input boxes Imprint Code The search performs a Begins With search on the Imprint Code field Type imprint codes including spaces to find results For example searching on MRK 4 will not produce a match but MRK 7 finds substances with the imprint MRK 74 and MRK 747 Note The application will automatically search the IDENTID Code information is typed If only imprint code information is known and you wish to search the Drug Images Database click the Drug Images Database option button then click the Search button EX System if only the Imprint Wt If any search parameters are entered for Description Shape or Pattern other than the default of All the Drug Images
121. est name test synonym panel test indication or drug name or you can Search for Keyword kd Search Find all lab tests that Exactly Match nd ia an asterisk iab aceta for Begin With search O Begin With Browse Lab Advisor Jump to 17 Hydroxyprogesterone measurement amniotic fluid A Select 1 Hydroxyprogesterone measurement serum erp Also known as a Keyword Search this option allows searches for lab information using the following a test name or synonym a drug name brand or generic an indication condition or common panel name Searching by a LOINC code is also available from this menu option Exactly Match versus Begin With The default search method Find all keywords that Begin With uses the search term as the root term and expands on it You may also be familiar with the term wildcard search The Begin With search acts like a wildcard search with the expansion to the right of the search term You can override the default search method if you don t find the results you expect when performing an Begin With search Narrow and focus your search results using the Exactly Match search method The Exactly Match considers matches only where the search term s exactly match a title synonym or index term character by character Note Any change you make to the Exactly Match or Begin With search parameter is maintained for t
122. esults Severity Documentation Summary T T i Concurrent use of ANGIOTENSIN CONVERTING ENZYME INHIBITORS and THIAZIDE DIURETICS may result in postural hypotension first dose T LISINOPRIL Systemic Prinivil HYDROCHLOROTHIAZIDE LISINOPRIL Systemic Q Houerate Good Prinzide i 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Note By default all Drugs all Severities all Interaction Types and all Documentation Types are displayed in the search results To change what is displayed in the results use the dropdown boxes in the Refine by area of the page Wet Severities Interaction severities are indicated by an icon and one word definition A complete legend of all severities is shown at the bottom of the page Hovering over the icon in the legend opens a pop up window with the full definition The full definitions follow 2 Contraindicated the drugs are contraindicated for concurrent use 6 Major the interaction may be life threatening and or require medical intervention to minimize or prevent serious adverse effects Moderate the interaction may result in an exacerbation of the patient s condition and or require an alteration in therapy Minor the interaction would have limited clinical effects Manifestations may include an increase in the frequency or severity of side effects but generally would not require a major alteration in
123. evidence is based on data derived from Expert opinion or consensus case reports or case series C No Evidence 2009 Thomson Reuters All rights reserved DISEASE INFORMATION Strength of Recommendation Strength of Recommendation The given test or treatment has been proven to be useful and should be performed or administered lass lla Recommended In Most The given test or treatment is generally considered to be useful and is ases indicated in most cases ass llb Recommended In Some The given test or treatment may be useful and is indicated in some but not ases most cases ass lll Not Recommended The given test or treatment is not useful and should be avoided ass Indeterminant Evidence Inconclusive Performance Measures Clinical Checklist can help clinicians and hospitals comply with key quality and performance measures i e guidelines published by JCAHO Centers for Medicare amp Medicaid Services etc at the point of care Organizations providing credentialing standards or compliance measures are listed by their abbreviation in the Performance Measure column The full organization name is found below the table Organizations Currently six organizations performance measures are included JCAHO Joint Commission on Accreditation of Healthcare Organizations CMS Centers for Medicare amp Medicaid Services AHRQ Agency for Health Research amp Qualit
124. exposures to substances as well as reproductive carcinogenic and genetic influences e Includes unique Dual Health Hazard Ranking System for general toxicity and grade card scale suggesting level of reproductive hazard e Helps set risk reducing priorities by combining hazard rankings with exposure estimates e Assists with development of programs to improve employee protection guidelines REPROTOX Reproductive Hazard Reference Developed by the Reproductive Toxicology Center Columbia Hospital for Women Medical Center Washington D C REPROTOX includes information such as the following e Provides information regarding the impact of the physical and chemical environment on human reproduction and development e Covers all aspects of reproduction including fertility male exposures and lactation e Discusses reproductive influences of industrial and environmental chemicals prescription over the counter and recreational drugs and nutritional agents e Includes latest most relevant teratology articles Shepard s Catalog of Teratogenic Agents Developed by Dr Thomas H Shepard Professor of Pediatrics University of Washington Co authored by Dr Ronald J Lemire Professor of Pediatrics University of Washington Director In Patient Services at Seattle Children s Hospital and Regional Medical Center Shepard s includes information such as the following e Electronic version of Shepard s Catalog e Up to date information on
125. eywords are terms which describe the information you seek You can search for documents by entering one or more keywords performing a search then clicking links to open the documents Every document has indexed keywords associated with it These terms correspond to the keywords entered on the Search page when you started your inquiry When the Micromedex Healthcare Series application finds documents associated with the keyword s you entered it displays a search result page Basic Search To begin a keyword search from the Main page enter the relevant search term or keyword s and click the Search button The system retrieves documents containing a match to the keywords entered Exactly Match vs Begin With If the Find all keywords that option button is set to search for an exact match only titles and synonyms that are identical to the search term will be returned If the Begin With option is selected the search term is treated like a wild card See Exactly Match versus Begin With on page 19 for more information on this search setting Boolean operators Boolean operators e g AND NOT OR etc are not necessary in the search terms For example a search for reye s syndrome returns documents that contain both terms as if they 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES were connected by the Boolean NEAR operator the terms are within 10 words from each othe
126. f index terms appendage appendectomy appendiceal appendicitis appendix and so on Search Results Matches to your keyword search are presented on one of two search results pages e Initial Results multiple matches were found in multiple databases e Narrow Results matches were found in multiple documents within a single database Initial Results Often a search can produce matches in many documents in multiple databases When matches are found in more than one database the Initial Results page is displayed 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Databases are organized into general information categories e g Summary Documents Drug Information Disease Information etc with the associated database names listed below and hypertext links to the right of each Note Only databases with a match on the search term are displayed on the Initial Results page Suppressing databases not containing a match cuts down on the amount of text clinicians must scan to find the answers to their questions T Go To links are provided at the top of the Initial Results columns to allow you to jump directly to a general information category if desired Search Path Main Keyword Search gt Your Search pneumonia Modify your search pneumonia Search Find all keywords that Exactly Match Begin With Summaries Drugs Disease Labs Alternative Medicine Reproductive Risk
127. f international literature discussing emergency and acute care medicine and includes clinical review clinical abstracts and prehospital care protocols The Clinical Checklist System is available to all DISEASEDEX subscribers and is the must do never do database It is a compilation of the most pertinent patient care interventions on commonly encountered conditions that should always or never be done The information is action oriented and concise and is based on nationally recognized quality standards and the highest rated medical evidence Each checklist item contains graded recommendation and evidence information These evidence ratings embed evidence based medicine into clinical operations and ultimately maximize reimbursement by ensuring that clinical decisions are in compliance with the latest national quality standards and evidence based practices ENHANCED DISEASEDEX CONTENT AND NAVIGATION In an effort to provide you with the disease information that meets your needs and answers your questions we conducted extensive research held multiple clinical focus groups and conducted surveys to understand your information needs A resounding majority stated that you wanted two levels of content brief and detailed 1 Provide the most critical information in the first level 2 Give the ability to click to second level content for additional information on tests treatment options and other valuable clinical information 2009 Tho
128. f outline title is reached the outline section numbers letters are deeper Using the ACEBUTOLOL document as an example Cautions Section 3 0 Adverse Reactions Section 3 3 Cardiovascular Effects Section 3 3 1 Acebutolol Hydrochloride Section 3 3 1 B Hypertension Section 3 3 1 B 3 Remember that regardless of how deep you maneuver into the outline from within the document itself you can always return to the top level outline by clicking the outline link located in the top of the document or continue Search Path Main Keyword Search gt Initial Results gt Document gt Document Outline DRUGDEX Evaluations ACEBUTOLOL o Overview Dosing Information Drug Properties Storage and Stability Adult Dosage Normal Dosage Dosage in Renal Failure Dosage in Hepatic Insufficiency Dosage in Geriatric Patients a Pediatric Dosage o Pharmacokinetics Onset and Duration Drug Concentration Levels a ADME Absorption Distribution Metabolism Excretion Elimination Half life Extracorporeal Elimination o Cautions Contraindications Precautions Adverse Reactions Cardiovascular Effects Acebutolol Acebutolol Hydrochloride Angina Cardiovascular finding Hypertension Intnemittant alaudinatinn navigate the first and second level sections using the floating outline on the left side of the document page 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE
129. from your PC monitor Log out by clicking either the icon or the link THOMSON i oe r 5 ARAFE Click the logo to jump to the Thomson Reuters Web site www micromedex com MUS Click on My Thomson Gateway to jump to return to the initial Log In page From the Log In page you can switch to other subscribed Thomson Reuters products 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved CHAPTER 2 MAIN Around the world the Healthcare Series databases are the medical profession s standard for database information systems These combined databases support clinical decision making and quality patient care by providing comprehensive disease drug acute care lab test and toxicology information The Micromedex Healthcare Series application offers easy access to the information you need Search a collection of databases simultaneously by selecting the Main Keyword Search page This search looks for all documents containing indexed terms matching your keywords in selected drug toxicology disease and laboratory test information databases Best of all the Micromedex Healthcare Series application is easy to use since you do not need to learn a complicated interface it s like using any search engine on the Internet You can instantly find all documents containing your search term s from the database s of your choice MAIN PAGE Keyword Search K
130. grouped according to rank The highest rank Results x is when the keyword or search term is found in the title of the document Title matches are followed by synonyms and related terms A related term match is when the keyword or search term is found in the document in indications interactions dosing in therapy of etc Click a link to open and view the document For more information on the Narrow Results page see Narrow Results on page 26 Refining Your Search If you complete a search and the search results include documents that do not apply to the information you desire you can quickly return to the Disease Information Specific Database Search by clicking the breadcrumb link or by clicking the Disease Information tab and selecting the Specific Database Search menu item Databases included in the Disease Specific Database Search e DISEASEDEX System General Medicine which includes e Clinical Reviews e Tests amp Procedures Studies amp Alerts 2009 Thomson Reuters All rights reserved DISEASE INFORMATION e DISEASEDEX System Emergency Medicine which includes e Clinical Reviews e Emergency Medical Abstracts EMA by Rick Bukata MD and Jerry Hoffman MD e Prehospital Care Protocols e Tests amp Procedures e Summary Documents the ClinicalPoints System which includes e General Medicine e Emergency Medicine e Tests amp Procedures Clinical Checklist For detailed inform
131. gs e Precautions e Drug interactions e Adverse reactions e Dosage and administration e How supplied e Manufacturer name POISINDEX System Commercial Pharmaceutical Biological Substance Identification amp Management The POISINDEX System identifies ingredients for hundreds of thousands of commercial pharmaceutical and biological substances Each substance is linked to one or more management documents providing information on clinical effects range of toxicity and treatment protocols for exposures involving the substances What s in POISINDEX The system contains the following modules e Product Substance Identification e Toxicological Managements POISINDEX documents follow this standard outline e Overview e Substances included synonyms e Clinical effects e Laboratory monitoring e Abstracts e Treatment 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Level of toxicity e Kinetics e Pharmacology Toxicology e Animal toxicology e References e Author information Product Substance Identification POISINDEX Product Substance Identification contains information on over 1 000 000 different household items such as e Common household products cleaners personal care insect protection e Industrial chemicals manufacturing agents e Industrial products cleaners protective agents e Pharmaceutical products prescriptions generic trade OTC veterinary Biological entities b
132. gy Foundation and the American Heart Association Inc Dallas TXAvailable from URL http vwww americanheart ora downloadablesheart1 061 222494555RNIFullTexFinal pdf 5 Gibbons RJ ACC AHA 2002 Guideline Update for Exercise Testing American College of Cardiology Foundation and the American Heart Association Inc Dallas TXAvailable from URL http Jwww americanheart orq downloadable heart 1 03227901 3658exercise pdf 6 American Heart Association 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Circulation 2005 112 24 Suppl IV 1 203 Available from URL httoyicirc ahajournals org contentivol112 24 suppl As accessed 12 14 2005 7 Joint Commission on Accreditation of Healthcare Organizations Specifications manual for national hospital quality measures version 1 05 Joint Commission on Accreditation of Healthcare Organizations Oakbrook Terrace LAvailable from URL http Jiwww icaho orv pms core measures aligned manual htm 8 Harrington RA Becker RC Ezekowitz M et al Antithrombotic therapy for coronary artery disease the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest 2004 126 3 Suppl 5138 5488 PubMed Abstract http wwww ncbi nim nih govw PubMed Article httosiwww ncbi nim nih qovs 9 Smith SC ACC AHA SCAI 2005 Guideline Update for Percutanenous Coronary Intervention American College of Cardiology Foundation and the Amer
133. h The default search method Find all keywords that Begin With uses the search term as the root term and expands on it You may also be familiar with the term wildcard search The Begin With search acts like a wildcard search with the expansion to the right of the search term You can override the default search method if you don t find the results you expect when performing an Begin With search Narrow and focus your search results using the Exactly Match search method 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES The Exactly Match considers matches only where the search term s exactly match a title synonym or index term character by character a maintained for the duration of your Micromedex active until you 1 Logout and 2 Close the browser window W Note Any change you make to the Exactly Match or Begin With search parameter is Healthcare Series session A session is Search AltCareDex Alternative Medicine Education For this condition or alternative medicine ire d Search Find all keywords that Exactly Match End in an asterisk iabt aceta for Begin With search Begin With OR view the Category List If you wish to search by browsing general condition categories click the Category List link See Search by Category on page 143 The search will find matches for the herb sup
134. h Path Tonic Substance List Search gt POISINDEX Product List gt POISINDEX Product POISINDEX Product List Next gt Drano Clog Remover Liquid Drain Opener Also known as Drano Liquid Drain Opener Liquid Drano Professional Strength Drain Opener Related Documents RI j NE POISINDEX Managements HYPOCHLORITES AND RELATED AGENTS POISINDEX Managements Ingredients Active Ingredients ater 82 to 92 Sodium Hypochlorite 4 5 Sodium Hydroxide 2 35 Sodium Silicate 1 1 Anionic Surfactant Less Than 0 1 Defoarning Agent Trace pH Value 11 5to 13 4 Availability amp Manufacturing POISINDEX Product List From the Product List page you can e view pertinent formulation information e click the lt Previous or Next gt buttons to move to the previous next product in the list of results e click the links for toxicologic managements for this product or substance to view treatment and management information Toxicologic Managements Synonyms 15 Results Product or Substance 20 Results Product or Substance Manufacturer Country AAPCC Poisindex Management s Drano Clog Remover Liquid Drain Opener Liquid SC Johnson Canada 011289 CORROSIVES United ALKALINE States HYPOCHLORITES AND RELATED AGENTS Canada 011289 CORROSI Quine Print Setup POISINDEX Managements CORROSIVES ALKALINE on OVERVIEW UFE SUPPORT CLINICA
135. h acts like a wildcard search with the expansion to the right of the search term You can override the default search method if you don t find the results you expect when performing an Begin With search Narrow and focus your search results using the Exactly Match search method 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION The Exactly Match considers matches only where the search term s exactly match a title synonym or index term character by character niii Note Any change you make to the Exactly Match or Begin With search parameter is maintained for the duration of your Micromedex Healthcare Series session A session is active until you 1 Logout and 2 Close the browser window W Initial Results The Initial Results page is displayed if matches were found for more than one database Results are organized by database name and content type The hypertext links to the right of the database name provides information on the type of information available For more information on the Initial Results page see Initial Results on page 23 Narrow Results The Narrow Results page is displayed when multiple matches are found within one database Results are grouped according to rank The highest rank Results x is when the keyword or search term is found in the title of the document Title matches are followed by synonyms Click a link to open and view th
136. he duration of your Micromedex Healthcare Series session A session is active until you 1 Logout and 2 Close the browser window aaa 233 paasi Wi Search results are organized by content type and displayed as hypertext links Click the link most appropriate for your to information question to view the document or document outline Search by Test Name Search for lab information using the full test name such as serum potassium measurement or part of the name potassium 2009 Thomson Reuters All rights reserved 1 Verify that Keyword is the option selected in the Search for listbox 2 Type the full test name in the text box If you are unsure of exact spelling change the selection from Exactly Match to Begin With and type the first few letters of the test name 3 Click the Search button Search Lab Advisor You can search ke dsb search by LO Search for Keyword x acid s by test name test synonym panel test indication or drug name or you can Find all lab tests that Exactly Match End in an asterisk iab aceta for Begin With search O Begin With If only one test name matches your search term the applicable lab document is opened for viewing If more than one test name includes the search term the Narrow Results page appears with a list of all results found Results are grouped into general categories such as e Results The search term
137. he secondary level click the section name containing the plus sign to expand to the second level Expand Allis a way to view all sections top and second level using one click Collapse All is a way to view only top level outline sections using one click Full Document Outlines Some documents in Micromedex Healthcare Series contain outlines up to six levels deep Navigation to all outline levels is still available by clicking the Outline link located at the top of every document 2009 Thomson Reuters All rights reserved Search Path Main Keyword Search gt Initial Results gt Document Click to view full document outline DRUGDEX Evaluations ACEBUTOLOL ACEBUTOLOL back to top Expand All Collapse All Overview Dosing Information Drug Properties Storage and Stability Adult Dosage Pediatric Dosage 0 Overview Pharmacokinetics lass Onset and Duration a This drug is a member of the Floating Outline Drug Concentration Levels i j ADME Antianginal Calos Antiarrhythmic Group II Contraindications Antihypertensive Beta Adrenergic Blocker Q Cardiovascular Agent 2 Dosing Information Precautions Adverse Reactions Teratogenicity Effects in Click the Outline link to open the complete document outline Click any of the outline section links to navigate directly to that section in the document Each time a lower level o
138. herapy acupuncture and other frequently used CAM therapies and treatments AltMedDex System Herbal and Dietary Information Part of the Complementary and Alternative Medicine CAM Series AltMedDex offers evidence based clinical information on herbal vitamin mineral and other dietary supplements The unbiased information is peer reviewed by a team of experts from both alternative medicine and traditional medicine communities Editorial board members performing the reviews include MDs DOs RPhs RNs and NDs What s in AltMedDex e Alternative Medicine Evaluations e Alternative Medicine Consults Alternative Medicine Evaluations Alternative Medicine Evaluations monographs appear in a standardized format that allows you to easily find the information you need Specific topics include the following e Dosing Information Synonyms e Pharmacokinetics e Cautions contraindications adverse reactions drug interactions e Place in therapy e Mechanism of Action e Therapeutic Uses Comparative Efficacy Alternative Medicine Consults Alternative Medicine Consults provide crucial information of interest to those needing information on herbal medicines and other dietary supplements Topics include FDA warnings pregnancy risk categories and guidelines on dosing safety and efficacy issues AltMedDex Protocols Complementary and Alternative Medicine Treatment Protocols 2009 Thomson Reuters All rights reserved DATA
139. hs weight kg lbs height cm in and sex male female Body Mass Index Calculator Body Mass Index BMI is a calculated value that shows body weight adjusted for height and indicates the weight status in adults Calculates BMI based on weight kg lbs and height cm in Body Weight Ideal Displays ideal body weight for men and for women based on height and frame size small medium large Conversion Factors Lists the multiplier to use to convert common values for example Bars to Atmospheres Inches of water to Pounds per square inch Millimeters of mercury Torr to Kilonewtons per square meter Temperature Conversions Lists values for Fahrenheit in Celsius and values for Celsius in Fahrenheit SIU Conversion Calculator 2009 Thomson Reuters All rights reserved Allows you to calculate and convert amounts based a selected substance and a chosen conversion unit Equivalents Practical Lists common equivalents such as linch is equal to 2 54 cm parts per million for liquids and the equation for finding the molecular weight for gases and vapors Metric Conversions Calculator Provides conversions between Metric and English standard units for many common conversions utilized in clinical practice The conversions include measurements of weight length volume temperature and parts per million Milliequivalents Lists the definition of a milliequivalent and how to calculate milliequivalent Also show
140. ic class This can be an especially useful search method when you aren t sure of the exact drug name but you do know the therapeutic class Search Path Therapeutic Classes To see subclasses click on the folder To see all drugs with summary information in the class cl GoTo os A B C DIElFIGIH Isi KILIMIN OlPla Ris Tlulyviwixlylz GYeSgeae G Anesthetic Local Amebicide Antibiotic Antifungal Antihelmintic Antimalarial Antiprotozoal C Antiseptic Antitubercular I Antiviral Leprostatic p Adrenocortical Suppressant Alkylating Agent Androgen Anthracycline The Therapeutic Classes page is organized in a hierarchical folder structure Top level therapeutic classes are denoted by the open file folder and listed alphabetically e g Anesthetic Agent Anti Infective Agent etc when you open the therapeutic class page Therapeutic subclasses are listed alphabetically beneath each class Anesthetic Local beneath Anesthetic Agent Amebicide Antibiotic Antifungal Antihelmintic beneath Anti Infective Agent etc A closed file folder means subclasses exist in that folder e To view lower levels of therapeutic classes click on the closed folder icon Only the lower level subclasses are shown in the expanded view Click the lower level subclass link to reveal the drugs associated To view the complete list of drugs for the class click the cl
141. ical Xpert powers your handheld device with a wealth of clinical knowledge from Thomson Reuters the industry s leading provider of evidence based decision support It s compatible with both Palm OS and Pocket PC s updated instantly at each sync with the latest information Your download gives you exclusive access to e disease information e laboratory test information Plus free access to information spanning e drugs e interactions e alternative medicine e toxicology e news amp alerts e calculators ClinicalPoints System The ClinicalPoints System provides brief highlights of treatment diagnosis and key point information The ClinicalPoints System delivers answers quickly and efficiently The System also links directly to the more in depth DISEASEDEX Emergency Medicine Clinical Review documents available only with a current DISEASEDEX Emergency Medicine subscription Current Concepts Program Continuing Education Program Thomson Reuters offers nine new modules online every quarter which can be completed for continuing education credit Although intended for pharmacists any healthcare professional may participate Micromedex a business of Thomson Reuters is approved by the American Council on Pharmaceutical Education Each module is approved for one hour of continuing education credit or 0 1 CEUs 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Detailed Drug Information
142. ican Heart Association Inc Dallas TxAvailable from URL http JAwww americanheart org downloadablesheart 1131740149971PCi Final Final i Home Contact Us Content Updates Training Center Warranty and Disclaimer Editorial Info About Us Help Log Out 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Search by Keyword Signs and Symptoms LOINC or ICD 9 Codes Our goal is to provide you with the answer you are looking for in the fastest way possible To that end we offer you three different search methods Disease Database Search Search for Find all keyword Keyword Searches for matches to the keyword on the title or on an associated synonym for a disease document For more information on keyword searches see Keyword on page 97 Signs amp Symptoms If you are researching a diagnosis by a specific symptom the Signs amp Symptoms search selection can find immediate matches based on your sign or symptom The Findings section of DISEASEDEX documents are searched for your matching search criteria See Signs and Symptoms on page 97 for step by step instructions on searching by signs and symptoms LOINC or ICD 9 Codes Additional information is a breeze when searching by either LOINC or ICD 9 codes Simply change the search selection to the appropriate code type and key in the code See page 97 for additional information on LOINC and ICD 9 code
143. ient care process For those cases requiring in depth research Evidence Xpert links back easily to the detailed Healthcare Series content you need to make an informed decision Plus end users can also toggle between the new point of care solution and the traditional in depth Healthcare Series Evidence Xpert offers Less clicks to get the answer you need e No lengthy documents to scan Seamless searching across content areas without re entering your search term e Word Wheel searching e Spelling help Plus Evidence Xpert provides enhanced summary drug information e Indications and Dosing now includes efficacy strength of evidence and strength of recommendation ratings e Regulatory Status and Generic Availability displayed in the summary document e Drug Toxicity provides information on clinical effects treatment and range of toxicity e Clinical Teaching offers point of care counseling information for clinicians to use when educating patients about their medications Designed for experts like you Teams of on staff experts bring real world experience to our decision support resources Doctors nurses pharmacists and other industry professionals help create solutions like the new Evidence Xpert to meet your specific needs Who can benefit from Evidence Xpert Point of care clinicians e Quick on the floor access e Intuitive workflow based interface e Trusted summary level information Pharmacists e
144. iew treatment and management information Click the POISINDEX Management link to view treatment and management information Product ID Search Results The Product ID search requires the full 7 digit unique POISINDEX product ID code to be entered as the search term The search looks for an exact match therefore only one result is retrieved for this type of search Results are shown in table format and display tradename e manufacturer e country e AAPCC code e POISINDEX Management s 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Need training to access clinical information at the point of care EJ Print Ready Calculators M Subscription Details Page Help Search Path Toxic Substance List Search gt POISINDEX Product List Showing Results 1 through 1 of 1 Trade Name Manufacturer Country AAPCC Poisindex Management s Alkylated Benzene Lubricant Ab150 Liquid Virginia Kmp United States 1077900 SYMPTOMATIC CHEMICAL INGESTION SYMPTOMATIC CHEMICAL DERMAL EXPOSURE Showing Results 1 through 1 of 1 Home Contact Us Content Updates Training Center Warranty and Disclaimer Editorial Info About Us Help Log Out Copyright 1974 2009 Product ID 6567634 Search Results Click the trade name link to view the Product List From the Product List page you can e view pertinent formulation information e click the lt Previous or Next gt buttons to move to the previo
145. in Healthcare Series Click the link to return to the Main Keyword Search page Contact Us Click the Contact Us link for a list of Thomson Reuters mailing address Email telephone and fax information Content Updates Click the Content Updates link to view a report of the new data and information included in the latest release of Healthcare Series Thomson Reuters recommends you check this link often to stay abreast of the new data features or information available in the Healthcare Series Training Center Learn about FREE online training services and display user education materials available for order by clicking the Training Center link Warranty and Disclaimer Displays the Micromedex Healthcare Series warranty and disclaimer Editorial Info For information on the Thomson Reuters Editorial Process and Editorial Boards About Us For information about Thomson Reuters Help Opens to the Table of Contents page for all topics in the Healthcare Series Help Help topics pertinent to a specific page in the application is available via the Help icon the picture of a question mark located in the upper right corner of a page The Help link at the bottom of each page allows you to browse all help topics from the Table of Contents Log Out 2009 Thomson Reuters All rights reserved UNDERSTANDING THE BASICS To prevent unauthorized access to the Healthcare Series application it is recommended you log out when you step away
146. iner information for this particular combination In cases where the drug was not tested with the solution listed Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to TPN TNA Overview tab name link Results can be viewed or printed See Printing Documents on page 30 for more information 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved CHAPTER 8 DRUG INTERACTIONS The drug interactions tool assists you in checking for interacting drug ingredients their effects and clinical significance With the correct information at the point of care a significant number of adverse drug events can be prevented The interactions tool provides instant access to drug drug drug food drug ethanol drug tobacco drug lab test drug pregnancy drug lactation drug alternative medicines ingredient duplication and drug allergy reactions SINGLE AND MULTIPLE DRUG INTERACTIONS Use the Drug Interactions page to check for single interatctions or for multiple interaction information The Check Interactions page also checks drugs against allergies Results are grouped by interaction type drug drug drug food drug lab etc Interactions found within each type are sorted by severity The list of severities follow e Contraindicated the drugs are contraindicated for concurrent use e Major the int
147. inical circumstances e Alternative Medicine Summary Information provides brief highlights of dosing indications contraindications adverse effects drug interactions therapeutic class pregnancy and lactation for herbals vitamins minerals and other dietary supplements 2009 Thomson Reuters All rights reserved All of the summary database documents include hypertext links to a corresponding document with more detailed and in depth information For example type acetaminophen click the Search summary documents only and click the Search button The Initial Results show matches for both the Drug Summary Information and POISINDEX Summary Information Click the Drug Summary link and a list of documents with the keyword acetaminophen are displayed Click the acetaminophen link to open that specific DrugPoints drug summary document The concise drug information for acetaminophen is displayed View at a glance the common tradename dosage indications contraindications adverse affects drug interactions pregnancy category and breast feeding rating Click the hypertext link within a topic to open the more detailed drug document DRUGDEX Drug Evaluation or Drug Consult opened and positioned right to the requested topic area I Maing Drugs Toxicology Disease Labs Interactions Patient Ed Handheld PDA Print Ready Calculators Ei Subscription Details Page Held 1V Compatibility Formulary
148. inition C Epidemiology F Etiologw Pathophysiology C Complications C History and Physical o Summary C Medical History C Findings C Diagnostic Testing C Diagnostic Testing Summary O Tests C Diagnosis C Differential Diagnosis C Treatment C Treatment Summary ail Drug Therapy C Procedural Therapy C Non Procedural Therapy C Prognosis O Disposition Select the sections to include by clicking the checkbox beside the section name Quickly select or de select all by using the Check All or Uncheck All links as appropriate Print Preview View a preview of the document by clicking the Display button From the print preview page print the document by selecting the print option from your Internet browser menu 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved CHAPTER 6 LABS Lab Advisor provides you with answers when you need evidence based laboratory test information Lab Advisor is a clinical laboratory database and contains critical information relevant to e Physicians e Saves time by providing information on which tests are appropriate for a condition or diagnosis Reduces the dependency on the lab the library or to reference textbooks e Saves time by providing guidance and information when interpreting test results Reduces the research time required to consult additional sources of information e Nurses e Answers questions about proper co
149. ions regulatory standards and compliance national healthcare and environmental health and safety trends FDA approvals editorial board suggestions and policy changes in health disease and chemical management from professional organizations Once chosen topics are researched thoroughly through exhaustive literature searches of thousands of articles medical and toxicology texts manufacturer data information from professional organizations and universities FDA approved package inserts and other authoritative resources Documents are drafted by Thomson Reuters scientific writers comprising physicians nurses pharmacists toxicologists and other healthcare specialists Peer Reviewed When the research and writing process is completed documents are peer reviewed to ensure the information contained in the Healthcare Series databases is accurate reliable and unbiased After material is incorporated into the databases all documents undergo a regular update cycle which further ensures continued accuracy and relevance to current practice Thousands of additions and revisions are made with each new release While new information 2009 Thomson Reuters All rights reserved INTRODUCTION 5 in continually added older references are retained to provide a historical perspective of landmark trials For more information about the Thomson Reuters editorial process and editorial boards visit our Web page at www micromedex com about us edit
150. is Acute Summary Search for diabetes with the Default Summary Documents Checkboxes Selected is shown above However the same search term diabetes searching across all databases yields many more matches on the Initial Results page 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Your Search diabetes Modify your search OR Did you mean diabetes Search DIABETES wv Search Find all keywords that oO Exactly Match Begin With Go To Summaries Disease Titles amp Synonyms DISEASEDEX General Medicine Results 2 Summary DISEASEDEX Emergency Medicine Diabetic ketoacidosis Acute Summary Titles amp Synonyms Related Terms amp Products gach toi DISEASEDEX General Medicine Clinical Results 59 Search Related Terms Reviews DISEASEDEX Emergency Medicine Results 42 Search Related Terms Clinical Reviews DISEASEDEX Tests and Procedures Continuous subcutaneous infusion ofinsulin Search Related Terms Clinical Reviews DISEASEDEX Studies and Alerts Results 6 DISEASEDEX Emergency Medical Results 62 Abstracts from Rick Bukata MD and Jerry Hoffman MD Search for diabetes Selecting all General and Emergency Medicine Databases For more information on the Initial Results page see Initial Results on page 23 Narrow Results The Narrow Results page is displayed when multiple matches are found within one database Results are
151. ise fully customizable materials to address patient condition treatment follow up care psychosocial issues continuing health and the most frequently administered drugs CareNotes information also helps meet JCAHO and OBRA 90 patient education guidelines Step by step information and instructions for the CareNotes System are available from within the application To access the CareNotes System select it by name from the Patient Education tab A second browser window and session opens Help for the CareNotes System is available within the application ALTERNATIVE MEDICINE EDUCATION Alternative Medicine Education Self medicating with herbals and other dietary supplements is commonplace as is treatment with acupuncture chiropractic care and homeopathy You can give your patients a better understanding of these healthcare alternatives with the AltCareDex System It offers easy to understand patient education materials to help answer questions about the use and impact of herbal products dietary supplements and treatment of medical conditions using complementary and alternative medicine CAM therapies To search for complementary and alternative medicine and treatment patient education materials select Alternative Medicine Education from the Patient Education tab Search by Name Type the name of the supplement herb or medical condition you wish to check Click the Search button Exactly Match versus Begin With keyword searc
152. izures Sexual Dysfunction Skin Color Changes Smell Disturbances Stridor Syncope Taste Disturbances Tear Abnormalities Thrombocytopenia Thrombocytosis Tinnitus Vaginal Bleeding 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES DISEASE Vision Color Changes Vitiligo Immunizations amp Prophylaxix Contagious Diseases Incubation Immunization Schedule Health Care Workers Malaria Prophylaxis Malaria Treatment Tetanus Prophylaxis Vaccine Injury Table Laboratory Values Anion Gap Cerebrospinal Fluid Analysis Cholesterol and Triglycerides Creatinine Clearance Phenytoin Level Adjustment Calculator Serum Chemistry Normal Values Synovial Fluid Analysis Measurement Calculators and Conversions Body Weight amp Surface Area Calculator Body Mass Index Calculator Body Weight Ideal Conversions Factors Equivalents Practical Metric Conversions Calculator Milliequivalents SIU Conversion Calculator Pediatric and Pregnancy References Apgar Score Pediatric Hypertension Pregnancy Risk Categories Vital Signs Pediataric LABS Laboratory Values Anion Gap Cerebrospinal Fluid Analysis 2009 Thomson Reuters All rights reserved DOSING TOOLS CALCULATORS
153. l line formula had the following composition per liter Compatibility Details The Compatibility Details page shows the detailed compatibility results for the drug selected on the search page Compatibility is denoted by the same icons and descriptions as shown on the overview page The full list of icons and descriptions can also be found in the Key at the bottom of each details page Details Page Navigation The Search Path or Breadcrumb The search path also known as a breadcrumb displays previous pages as links On the details 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES page it is displayed as Search Path IV Single Compatibility gt Compatibility Overview gt Clicking the IV Single Compatibility link takes you back two steps to the Single Drug search page Clicking the Compatibility Overview link takes you back one step to the Single Drug Overview page Start a New Search To search for compatibility information for a different drug click the Modify Your Search button to return to the Single Drug Search page The more details Link A more details link is placed next to the drug name at the top of the page Click this link to jump to the bottom of the page to view summary drug information i e trade names and pH range and Reference citations for the test results shown Solution Details Solution compatibility details for single drug compatibility searches are shown in
154. list Documents Summary Information Clinical Checklist is available to all DISEASEDEX subscribers at no additional charge The Clinical Checklist System is the must do never do database It is a compilation of the most pertinent patient care interventions on commonly encountered conditions that should always or never be done The information is action oriented and concise and is based on nationally recognized quality standards and the highest rated medical evidence Clinical Checklist documents include links to DISEASEDEX documents for more detailed and in depth information Links to related information in drug lab disease and toxicology are also included when appropriate for the topic selected Search for Clinical Checklist documents Clinical Checklist documents are available from the Main gt Keyword Search and the Disease gt Specific Database gt Keyword Search only Search Results If a Clinical Checklist document is found for your search term s the search results display the icon green checkmark and the hypertext link displays either the number of matches found in the Results x or the document title if only one match is found 7 Note Note Quality Managers Librarians Nurse Managers and others may be interested in searching Clinical Checklist by performance organization or quality standard See Searching by Performance Measure on page 93 We Each checklist item contains graded recommendation a
155. ll Overview Dosing Information Drug Properties Storage and Stability Adult Dosage Pediatric Dosage Pharmacokinetics Onset and Duration Drug Concentration Levels ADME Cautions Contraindications Precautions Adverse Reactions Teratogenicity Effects in Pregnancy Breastfeeding Drug Interactions Clinical Applications Monitoring Parameters Patient Instructions Place In Therapy Mechanism of Action Pharmacology Therapeutic Uses Comparative Efficacy Evaluation With Other Therapies References 2009 Thomson Reuters All rights reserved 3 5 Drug Interactions Drug Drug Combinations Drug Food Combinations 3 5 1 Drug Drug Combinations Amantadine Betamethasone Budesonide Carbamazepine Carbimazole Cimetidine Clobetasone Clorgyline Corticotrapin Cortisone Cosyntropin Danazol Deflazacort Desipramine Desonide Dexamethasone Droperidol Flecainide Fludrocortisone Flunisolide Fluoxetine Fluticasone Fosphenytoin Guanfacine Haloperidol Hydrocortisone Imipramine lproniazid lsocarboxazid Levodopa DRUG INFORMATION Document Outline The document opens with the document outline displayed on the left side of the screen The outline will float on the page so it is always available to you as you navigate through the document The outline sections are shown as links and are fully navigable Click a section name to jump directly to that sec
156. llection storage and administration procedures e Provides information on unfamiliar or rarely administered tests e Enables nurses to find answers to lab related questions after lab hours or when a lab technician is unavailable e Lab Personnel Saves time by reducing the number of calls from clinicians e Can communicate lab protocols specific to your facility a future enhancement coming soon e Pharmacy Personnel e Provides information when monitoring patient drug levels therapeutic levels and possible side effects related to lab tests Options available in Lab Advisor Specific Database Search Search by a Keyword Keywords can bea test name indication condition drug name or common panel name Search by LOINC Logical Observation Identifiers Names and Codes code number e Browse a list of test names Specific Topic Search e A full text search for specified terms within specific sections of a lab document Click one of the options listed on the Labs tab to work in the Lab Advisor database 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES SEARCH A SPECIFIC DATABASE Ween MICROMEDEX Healthcare Series MICROMEDEX Main Drugs Toxicology Disease IV Compatibility Interactions Patient Ed Formulary Handheld PD Ei Subscription Details Page Specific Database Search shy Specific Topic Search Search Path Lab Database Search Search Lab Advisor J t
157. lly 500 ml 24 hours itis termed as oliguria and less than 50 ml 24 hours is called anuria Itis important to note that no universally accepted definition or classification for the ARF syndromes currently exists but are being actively developed Medical History Diabetes mellitus e Renal impairment acute e Rhabdomyolysis e Hypertension Jump to a particular section in the Summary document by clicking the section name in the floating outline on the left side of the page Go to the more detailed Clinical Review document or to a Lab Advisor test document for this topic by clicking on a hypertext link Go to a related summary document ToxPoints DrugPoints or another ClinicalPoints document by clicking a hypertext link For example clicking on the Medical History link in the document above opens the Acute renal failure Clinical Review directly at the Medical History section in the document Clinical Review documents open with top level information and although more detailed than ClinicalPoints documents they are still presented with the most critical information first The layout of the Clinical Review is presented in an easy to read format allowing for fast review and retri eval of the desired information 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Medical History Acute renal fai S Expand All Collapse All Tabetes mellitus Back d Renal impairment acute z rte Rh
158. mson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Go Direcily to the Information You Need We are pleased to announce that the default selections for a Disease Specific Database Search returns matches to the ClinicalPoints summaries of our DISEASEDEX General and Emergency Medicine documents Going directly to the summary documents allows you to find a quick answer from the high level document without having to work through extra information Our enhanced summary content contains links for fast access to more detailed or related information on the topic if necessary For more information on ClinicalPoints See ClinicalPoints Documents Summary Information on page 89 Also shown in summary document Search Results are matches if found in the Clinical Checklist database If a match is found the icon green checkmark is shown and the hypertext link shows either the document title or the number of results For more information on Clinical Checklist documents Search for Clinical Checklist documents on page 91 Search Path Main Keyword Search gt Initial Results Your Search renal failure Modify your search OR Did you mean renal failure Search Find all keywords that Exactly Match Begin Search With The default search returns matches in the Summary databases GoTo Summaries Drugs Disease Labs Toxi f Alternative Medicine Summary Documents YA Results 2 Clinical Checkli
159. multiple studies and full study information including manufacturer concentration stability and other conditions e Helps clinicians interpret conflicting compatibility results by identifying contributing factors e Includes 600 unique drugs and solutions 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Over 50 000 compatibility results e Provides solution Y Site syringe and admixture compatibility information e Includes TPN TNA data e Allows for either single or multiple drug searches Lab Advisor Evidence based laboratory test information Lab Advisor is a clinical laboratory database which presents the most critical information about which laboratory tests are appropriate for a given condition interpretation and management of results normal ranges test methodology and other laboratory related information Lab Advisor will e describe which tests are appropriate for a given indication e help streamline workflow by providing actionable information that eliminates the need to call the lab or library with questions about administering and interpreting labs e aid in the interpretation of test results e link to summary level drug disease and toxicology documents for more detailed information on the topic or substance e provide evidence based testing information on how and when to monitor drug levels therapeutic levels and side effects e provide normal or therapeutic r
160. nd evidence information These evidence ratings embed evidence based medicine into clinical operations and ultimately maximize reimbursement by ensuring that clinical decisions are in compliance with the latest national quality standards and evidence based practices All information is displayed ina 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES concise format and is organized first by what a clinician should Always Do and is followed by what a clinician should Never Do Main Drugs Toxicology Labs IV Compatibility Interactions Patient Ed Formulary Handheld PDA EEJ brine Ready EF calculators fig Subscription Details Page Help Search Path Main Keyword Search gt Initial Results gt Document Acute coronary syndrome Acute Links to the Always Do subsections Go to Diagnosis Treatment Disposition Links to the Never Do section of the document back to top E 82 e Naver Do section othe doouner Diagnosis Strength of Performance Recommendation Strength Measure back to top of Evidence Diagnostic Testing Obtain a 12 lead ECG immediately within 10 minutes in all patients who present with ongoing chest discomfort and as soon as possible in patients whose pain has resolved but who have a history of chest discomfort that is consistent with acute coronary syndrome ma Obtain serial ECGs at 5 to 10 minute intervals or perform continuous ST segment monitoring in patients who remain
161. ners lye insecticides In general the broader the term or phrase the more results you will find Similarly the more specific the term the fewer results you will find as seen in the following diagram 2009 Thomson Reuters All rights reserved Enter Few Terms Enter Many Terms Receive Many Results Receive Few Results Occasionally you may not get the result you were expecting In this case try one of the following strategies explained below e Use multiple keywords e Use a synonym e Expand your search keywords e Limit your search keywords e Expand your search to look for matches on the term as well as expansions of the term by selecting the Begin With search option If you are unsure of the correct spelling type just the first few letters and check that the Find all keywords that Begin With option is selected The search will treat any expanded matches to the keyword root as a possible match and add it to the search results Exactly Match versus Begin With The default search method Find all keywords that Begin With uses the search term as the root term and expands on it You may also be familiar with a wildcard search the Begin With search is similar The Begin With search acts like a wildcard search with the expansion to the right of the search term You can override the default search method If you don t find the results you expect when performing the defaul
162. ng the elderly during 1989 2002 Conclusions Influenza vaccination coverage among the general U S elderly population exceeded the Healthy People 2000 goal of 60 but not among non Hispanic black and Hispanic populations and overall coverage has leveled off since 1997 according to a study reported in Archives of internal Medicine Methods Researchers analyzed data from the 1989 1991 1993 1995 and 1997 2002 National Health Interviews Surveys NHIS to determine rates of influenza vaccination in the noninstitutionalized elderly population 65 years and older in the United States Researchers also conducted a multivariable logistic regression modeling of the 2002 NHIS data to identify factors independently associated with influenza vaccination Results Study results showed that influenza vaccination coverage significantly increased from 30 5 in 1989 to 65 6 in 2002 The vaccination coverage grew steadily between 1989 and 1997 and then leveled off with an increase of 2 4 from 1997 to 2002 Influenza vaccination coverage was also lower among the non Hispanic black and Hispanic populations for all years studied with a rate of 49 6 among the non Hispanic black population and 48 5 among the Hispanic population in 2002 compared with non Hispanic whites 68 6 Those who were least likely to get vaccinated were people who had fewer than 4 physician contacts in the last year or did not have a regular physician were divorced or separated were non
163. ngth of recommendation ratings definitions and additional details for a statement in the drug summary document Print Comparisons See Printing Documents on page 30 for more information on printing Change the Documents in the Display Columns Change the drugs in the two columns by clicking the down arrow in the dropdown box below the column heading Select a different drug to display then click the Display button to refresh the page Display in Column One AMOXICILLIN Display in Column Two v CIPROFLOXACIN v AMOXICILLIN CEPHA HYDROCHLORIDE CIPROFLOXACIN gt PENICILLIN G BENZATHINE PENICILLIN G PROCAI Modify Drugs to Compare 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES To add or delete a drug from the list for comparison click the Modify Your Search button The page with the drugs used for comparison is shown Remove an individual drug by selecting the Remove checkbox to the right of the drug s you wish to remove from the comparison list and clicking the Remove button Return to the side by side comparison page by clicking the Display Comparison button Clear all drugs in the list by clicking the Clear button 2009 Thomson Reuters All rights reserved DRUG INFORMATION TRADE GENERIC LISTS The Trade Generic Lists can provide you with fast access to basic drug information such as e Ingredients e Availability and Manufacturer
164. nk to view the details of these tests Compatibility Details The Compatibility Details page shows the detailed compatibility results for the drugs chosen on the search page Compatibility is denoted by the same icons and descriptions as shown on the overview page The full list of icons and descriptions can also be found in the Key at the bottom of each details page Details Page Navigation The Search Path or Breadcrumb The search path also known as a breadcrumb displays previous pages as links On the details page it is displayed as Search Path IV Multiple Compatibility gt Compatibility Overview gt Clicking the IV Multiple Compatibility link takes you back two steps to the Multiple Drug search page Clicking the Compatibility Overview link takes you back one step to the Multiple Drug Overview page 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Start a New Search To search for compatibility information for a different set of drugs click the Modify Your Search button to return to the Multiple Drug Search page The Checking Compatibility For Links All of the drugs searched are shown as hypertext links Clicking a drug name link will open the solution overview page for a single drug compatibility result Y Site Details Y Site compatibility details for multiple drug compatibility searches are shown in a five column table e The first column contains the drug name the concentration and the manufact
165. ns multiple 135 Drug Summary Information 20 DRUGDEX System 47 153 DrugPoints System 154 DRUG REAX System 155 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES E Editorial Information 14 Emergency Medical Abstracts EMA by Rick Bukata MD and Jerry Hoffman MD 101 EPA code 68 F Formulary Advisor 145 155 G Go To speed menu 64 H handheld 145 HAZARDTEXT Hazard Managements 80 164 Help 14 Herbal Medicines A Guide for the Health Care Professional 156 Home 7 14 hypertext links 24 l i icon 22 56 78 98 CD 9 96 97 DENTIDEX System 156 mmunizations amp Prophylaxis 38 imprint code 50 ndex Nominum 157 NFOTEXT Documents 80 nteractions multiple drug interactions 135 V INDEX System 119 157 J JCAHO 141 K Keywords that Begin With 18 19 that Exactly Match 19 L Lab Advisor 109 Laboratory Values 39 Logging out 14 LOINC 96 97 LOINC code 109 114 M manufacturer information 47 MARTINDALE The Complete Drug Reference 47 159 Material Safety Data Sheets see MSDS from USP Measurement Calculators and Conversions 40 MEDITEXT Medical Managements 80 164 MSDS from USP 80 160 My Thomson Gateway 15 N Narrow Results 26 NDC code 68 NS 127 0 OBRA 90 141 P P amp T QUIK Reports 160 Palm OS 145 151 PCP 68 PDR 160 Pest Control Product 68 Physicians Desk Reference 160 Pocket PC 145 151 POISINDEX System 80 161 Preve
166. ns are shown as links and are fully navigable Click a section name to jump directly to that section in the document You may also scan the entire document by using the scrollbar When the document is opened the outline is shown in fully expanded state Click the Collapse All link to compress the outline to the first level of the outline Section names with a plus sign denotes that additional sub sections exist below Click the section name with the plus sign to move to that section and view the sub sections For more information on document outlines see Floating Document Outlines on page 27 Print Setup and Print Ready Management Highlights Background Diagnosis Treatment Complications Special Circumstances When to Consult or Refer Prognosis Patient Education Follow up Prevention and Screening Drugs To Consider Key References Literature Cited Author Information Tables and Figures Two print options are available from within a document Print Ready and Print Setup 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Main Drugs Toxicology Labs IV Compatibility Interactions Patient Ed Formulary Handheld PDA New Order Sets Solution Preview 5 Print Ready f Subscription Details Page Help Search Path Disease Database Search gt Initial Results gt Document Outline Print Setup DISEASEDEX General Medicine Deep venous th bac Expand All Collapse All
167. ntion 89 Print documents 30 print partial documents 31 Print Ready 30 print selected text 31 Print Setup 31 Print Ready 30 R related documents 48 Related Terms 26 REPRORISK System 80 162 REPROTEXT Database 80 162 REPROTOX 80 162 Results x 24 S Screening 89 select databases 21 Severities 139 Shepard s 80 162 Signs amp Symptoms 96 Solution 127 130 Strength of Evidence 57 92 115 Category A 57 115 Category B 57 116 Category C 57 116 No Evidence 57 116 Strength of Recommendation 57 92 116 Class 57 116 Class lla 58 116 Class llb 58 116 Class Ill 58 116 Class Indeterminant 58 116 Studies amp Alerts 90 Summary documents 20 synonyms 23 Syringe 122 124 128 132 T Tabs 8 10 Disease 9 Drugs 8 Interactions 9 IV Compatibility 9 Labs 9 Patient Education 10 Toxicology 8 TERIS 80 162 Tests amp Procedures 90 Therapeutic Classes 63 Thomson Gateway see My Thomson Gateway TOMES System 80 164 Toxicologic Management Summary Information 20 Toxicology 65 ToxPoints System 80 165 TPN TNA 129 132 Training 14 U UPC code 68 Updates see Content Updates Ww warranty 14 wildcard 23 Y Y Site 122 123 128 131 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved
168. nts and licensed uses Cross references link each ingredient to an appropriate drug monograph when possible In addition more than 600 disease treatment reviews offer overviews of the diseases and drugs used in their treatment along with key references Cross references are provided between disease reviews and relevant drug monographs MARTINDALE coverage includes e More than 5 300 drug monographs e Over 70 000 proprietary preparations 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Atleast 6 000 manufacturers e More than 600 disease treatment reviews e Over 200 herbal medicine monographs e Atleast 5 000 herbal preparations Material Safety Data Sheets MSDS Prepared by the US Pharmacopeial Convention Material Safety Data Sheets are a vital part of every hospital company Hazard Communication Program This electronic version of more than 1 000 MSDS issued by the US Pharmacopeial Convention offers quick access to drug and chemical information including health hazards handling procedures and government regulations What s in MSDS Each sheet contains summaries of key information about hazardous substances in the following format e Identify e Hazardous ingredients e Physical and chemical characteristics e Physical hazards e Health hazards e Special protection information e Special precautions and spill leak procedures P amp T QUIK Reports Reports for Pharmacy amp Therapeutics
169. od and Fair and Unknown are included and shown in the Documentation dropdown list To remove any type from the interaction results de select it uncheck the box and then click the Update button 4 The Type dropdown allows you to filter for specific interaction types only For example you could change the selection to view only drug drug interactions Jump To Interactions are shown grouped by interaction type Drug drug interactions are shown first on the page followed by drug food drug ethanol then drug lab Jump To Drug Drug 2 Drug Alleray 3 Drug Food 7 Drug Ethanol 3 Drug Lab 7 Drug Tobacco 2 Drug Preqnancy 7 Drug Lactation 7 The Jump To links show at a glance how many interactions of each type exist and allow you to go quickly to a particular type Click the link to go immediately to the first entry in the interaction type 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved CHAPTER 9 PATIENT EDUCATION The more patients understand about their conditions and care the more comfortable they are likely to become with their treatment Patient education documents enable you to conveniently provide your patients with complete easy to understand information about all aspects of their care and health THE CARENOTES SYSTEM The CareNotes System Presented in English and Spanish the CareNotes System provides conc
170. ode e Color Shape Form e Active amp Inert Ingredients Container e Regulatory Status e NDC Code s e Manufacturer Name Product ID Image POISINDEX Product List Chierzexazone Related Docimments SHELETAL MUSCLE RELAXANTS CENTRAL ACTING POISINDEN Managements GHLORZOMAZONE ORUGDEX Evaluations Regulatory Status RX Ingredients Active Ingredient Chiorzoxazone 500 MG Exciplonas Silicon Dioxide Colloidal Crosearmeliore Sodium s anhydrous Magnesium Stearate microcrystamine celulose Sodium Benzoate DEC Yellow No 10 Lake FORC Piue No 1 Lake Available Container Sizes Dottie of 100 Dottie of 1000 Donie of 20 Hottie of 500 unit dose package of 100 Marmitacturer Garr Laborsiories Product M 4156968 AAPCE Code 177000 Registry Mumbers NOC 51079 047620 NOC 00555 050510 NOC 00555 0585 05 NOC 00555 0505 04 NOC 00555 0585 02 Notes Hotes The letter b in me word barr is the barr logo 9 lowercase letter b with a hexagonal base Physical Description Imprint Barr 555 585 Form Tablet Color light green Shape Circle scored Images for NDC 00555 0505 04 fnages for NDC 009535 0505 02 2009 Thomson Reuters All rights reserved DRUG INFORMATION The Drug Images Database drug identification tool returns an image and description of the substance so you are able to visually confirm that you have located the substance in question You can jump to the IDENTIDEX System from the Drug Imag
171. olyamine toxins curtatoxins or agatoxins that have paralytic and insecticidal activity The polyamine portion rather than the acyl moiety of these toxins appears to be more crucial to the paralytic potency in insects Quistad et al 1991 Adams et al 1989 D Originally the major toxin was thought to be atraxotoxin a protein of MV 9 800 consisting of 97 amino acids However Sheumack et al 1983 isolated the sole lethal toxin robustoxin from the venom of the male funnel web spider A robustus and determined the molecular weight of the lethal polypeptide neurotoxin to be 4 887 The complete sequence of 42 amino acids has been determined Sheumack et al 1985 1 Collins et al 1995 have suggested that a pre robustoxin molecule may be present in the venom ofthe male species Further study is required to determine the possible significance of this finding E Experimentally venom of the male A robustus is atleast 6 times as toxic as that of the female due to differing toxin content Historically ofthe 13 deaths positively attributed to envenomation by the funnel web spider Atraxtobustus all have been due to male spiders Sutherland 1983 F venom components cause excessive neurotransmitter release at autonomic and somatic TOXICOLOGY INFORMATION Document Outline The document opens with the document outline displayed on the left SPIDER FUNNEL WEB side of the screen The outline will float on the page so it is always Pe
172. om Exactly Match to Begin With and type the first few letters of the drug name 2009 Thomson Reuters All rights reserved 3 Click the Search button For example if you searched on cortisone using this method Lab Advisor finds only one possible drug lab interaction match Digoxin Measurement Since only one match was found the document is opened When multiple matches are found you are presented with the Narrow Results page where you click the test name link to view the lab document Lab Advisor documents include section outlines to aid in fast navigation throughout the document See The Lab Advisor Document Outline on page 115 for more information Print the document See Printing Lab Advisor Documents on page 116 Search by Indication or Condition Search by the suspected indication or condition to assist in determining which tests are recommended to diagnose the condition 1 Verify that Keyword is the option selected in the Search for listbox 2 Type the indication or condition in the text box If you are unsure of exact spelling change the selection from Exactly Match to Begin With and type the first few letters of the drug name 3 Click the Search button For example if you searched on diabetes using this method Lab Advisor finds and displays many tests as matches on the Narrow Results page To view an individual lab document click the test name link L
173. on pediatric or adult weight in kilograms or pounds this calculator displays the medications and recommendations according to the American Heart Association guidelines for ACLS PALS neonatal resuscitation Dobutamine and Dopamine Dosing Calculators Both of these tools calculate based on weight kg lb and the initial dosing Results are in mcg kg min with the selected solution Epinephrine Calculators Adult and Pediatric The adult calculator displays recommendations based on initial dosing and the solution concentration The pediatric calculator also factors in the weight kg Lb of the pediatric patient Heparin Dosing Calculator Formulates recommendations based on weight kg lb and units ml IV Rate Calculator Enables clinicians to quickly and easily determine the infusion rate for medications that require complicated calculations This flexible dosing tool is not specific to a particular drug but calculates an infusion rate for a variety of medications dosing options and solution concentrations Nitroglycerin Dosing Calculator Dosing calculations are for adults only weight gt 40 kg Calculations are not based on patient weight Recommendations can be calculated based on concentration and mcg min and whether or not the patient is on fluid restriction Nitroprusside Dosing Calculator Calculations are based on patient weight kg lb and mcg kg min and the concentration of the solution used 2009 Thomson Reuters
174. ons Back to top Infection of skin AND OR subcutaneous tissue 250 mg ORALLY every 6 hr OR 500 mg ORALLY every 12 hr Osteomyelitis 250 mg ORALLY every 6 hr dose range 250 mg to 1 g ORALLY every 6 hr depending on type and severity of infection Otitis media 250 mg ORALLY every 6 hr dose range 250 mg to 1 g ORALLY every 6 hr depending on type and severity of infection Respiratory tract infection 250 mg ORALLY every 6 hr dose range 250 mg to 1 g ORALLY every 6 hr depending on type and severity of infection Streptococcal pharyngitis 250 mg ORALLY every 6 hr OR 500 mg ORALLY every 12 hr Urinary tract infectious disease 250 mg ORALLY every 6 hr dose range 250 mg to 1 g ORALLY every 6 hr depending on type and severity of infection ORALLY 3 times a day in combination with lansoprazole 30 mg ORALLY 3 Scan the two summary documents quickly using the scrollbar For more in depth information about a drug click the link to open the corresponding DRUGDEX Drug Evaluation to the specified area in the document Click the drug name link at the top of the column to open the DRUGDEX Drug Evaluation document to the Overview section From the overview you can move to any other section in the document by clicking on the outline hypertext link Links in Drug Summaries Supporting information for the document may be displayed as a hypertext link Examples of supporting information include a full list of trade names strength of evidence stre
175. ontent type and displayed as hypertext links if a match exists If no matches were found the database is not listed in the Initial Results Click the link most appropriate for your to information question to view the document or document outline For more information on search results see Initial Results on page 23 and Narrow Results on page 26 Strength of Evidence In some documents a Strength of Evidence link is shown This provides the reader with a weighting that they can attach to the evidence shown The rating is organized into four categories Category A through Category C and No Evidence Click the link to view the definition of the category e Category A evidence is based on data derived from Meta analyses of randomized controlled trials with homogeneity with regard to the directions and degrees of results between individual studies Multiple well done randomized clinical trials involving large numbers of patients Category B evidence is based on data derived from Meta analyses of randomized controlled trials with conflicting conclusions with regard to the directions and degrees of results between individual studies Randomized controlled trials that involved small numbers of patients or had significant methodological flaws e g bias drop out rate flawed analysis etc Non randomized studies e g cohort studies case control studies observational studies e Category C evidence is based on dat
176. option from your Internet browser menu For more print options and information on printing documents see Printing Documents on page 30 2009 Thomson Reuters All rights reserved CHAPTER 5 DISEASE INFORMATION With more treatments being developed and put into practice every day it is difficult to find time to research the latest treatments of choice even for the most common of ailments Disease information available in Healthcare Series is loosely categorized by treatment type General Medicine and Emergency Medicine The DISEASEDEX General Medicine System supports disease management with unbiased evidence based information and identification of best practices for treating diseases It lets clinicians quickly reference the most current treatment of choice at the point of care to help minimize errors prevent unnecessary tests or procedures reduce treatment costs and improve patient outcomes Delivers both detailed etiology and treatment information along with summary overviews for each medical condition providing recommendations for appropriate care The DISEASEDEX Emergency Medicine System is designed to assist in the rapid effective diagnosis and treatment of patients in acute care settings Evidence based it instantly answers the what when and how of emergency medicine Information includes clinical presentation laboratory and diagnostic findings and therapeutic modalities Provides an ongoing cumulative review o
177. orial About This Manual This manual has been designed to print double sided If you print this manual in a single sided layout blank pages will print These blank pages are intentional Examples used throughout this manual illustrate a customer with a subscription to all of the Micromedex Healthcare Series databases features and products Your application may look different as unsubscribed products are suppressed from view to remove extraneous text and options For purposes of training illustration and clarification fictitious hospitals and groups i e Exemplary Healthcare MidTown Hospital etc may be used throughout this manual Each chapter in this manual covers an important feature or function in the Healthcare Series application Most chapters begin with broad overview information and then proceed to drill down to additional details and specific step by step instructions All chapters include sample search and data retrieval scenarios to assist in your comprehension 2009 Thomson Reuters All rights reserved 6 MICROMEDEX HEALTHCARE SERIES 2009 Thomson Reuters All rights reserved CHAPTER 1 UNDERSTANDING THE BASICS The developers engineers and designers at Thomson Reuters utilized extensive research and development and employed a user centered design process to create the newest Healthcare Series application One of the highest priorities throughout this process was to build an application that m
178. otanic zoologic food poisoning Toxicological Managements Toxicological Managements offers over 850 detailed courses of treatment for someone exposed to a substance REPRORISK System Reproductive Risk Information The REPRORISK System is a unique collection of reproductive risk information databases It provides information covering full range health effects that is helpful when assessing reproductive risks of drugs chemicals and physical and environmental agents Risks to females males and unborn children are discussed What s in REPRORISK The REPRORISK System can define potential problems for women men and the effect on unborn children It also can define risks associated with drugs and other substances both legal and illicit The REPRORISK System suggests treatment plans to minimize risks during pregnancy REPRORISK includes the following modules e REPROTEXT Database e REPROTOX Reproduction Hazard Information e Shepard s Catalog of Teratogenic Agents e TERIS Teratogenic Information System REPROTEXT Database Reproductive Hazard Reference 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS REPROTEXT includes information such as the following e Presents in depth reviews on full range health effects of industrial chemicals commonly encountered in the workplace e Covers physical agents including heat noise and radiation e Describes effects on human reproduction of acute and chronic
179. ou easy access to current accurate drug knowledge you can use with confidence Reviewed by experts Healthcare Series drug documents are evidence based cover FDA approved and investigational prescription and nonprescription drugs as well as non U S preparations Areas discussed include dosage pharmacokinetics cautions interactions clinical applications adverse effects comparative efficacy drug of choice information and orphan drug status COMPARE DRUG SUMMARIES View and compare drugs side by side with the Compare Drug Summaries feature Compare attributes such as dosing administration indications contraindications precautions adverse effects interaction information etc to assist you in making the most informed choice Search for up to 20 drugs to compare Two drugs are displayed and printed at a time to allow for easy comparison and review with colleagues Switch the two drugs in the pair with any other drug searched Enter Drug Names to Compare To create a drug comparison e from the Drugs tab select the Compare Drug Summaries option YN MICROMEDEX Healthcare Series MICROMEDEX Toxicology Disease Labs IV Compatibility Interactions Patient Ed Formulary Handheld PDA Ei Subscription Details Page Help Search Path Compare Drug Summaries Compare Drug Summaries Enter drug names to compare Search Clear Show 2 Entry Fields e Type the tradename or the generic drug name in the
180. p Anosima Ascites 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES DISEASE Ataxia Back Pain Chest Pain Constipation Creatine Kinase Dementia DIC Clinical Syndromes Diplopia Dystonia Eosinophilia Fecal Discoloration by Agent Fecal Discoloration by Color Fever of Unknown Origin GI Bleeding Lower Gynecomastia Hallucinations Hearing Loss Hematemesis Hematuria Hemoptysis Hemorrhagic Disorders Hiccups Hirsutism Hypenatremia Hypercalcemia Hyperglycemia Hyperkalemia Hypermagnesemia Hypernatremia Hyperphosphatemia Hyperuricemia Hypocalcemia Hypoglycemia Hypokalemia Hypomagnesemia Hypophosphatemia Hypothermia 2009 Thomson Reuters All rights reserved DOSING TOOLS CALCULATORS NOMOGRAMS amp REFERENCES DISEASE Impotence Jaundice Lactic Acidosis Leukocytosis Leukopenia Malignant Hyperthermia Metabolic Acidosis Miosis Mydriasis Nail Changes Neutropenia Nystagmus Oral Changes Pancreatitis Photophobia Polycythemia Polyuria Positive Direct Antiglobulin Test Priapism Proteinuria Pruritus Psychosis Extreme Anxiety Ptosis Renal Failure Acute Rhabdomyolysis Se
181. p Handheld PDA csssccsssccssccnsccsssccssccesceeesees 145 Formulan ee crna E E nln th atid E A a sa sbet eis AERAR 145 Thomson Clinical Apere A ee E TE E EE E E A EEEE 145 Appendix A Database Descriptions sscccscccssccsseccscccesccnsccescccescensceess 147 Micromedex Healthcare Series Database cccccccsccccssscccssececcsseeeesseecessseecsssseeeseeeseneeeens 147 Appendix B Dosing Tools Calculators Nomograms amp References 167 MWY acces esa A E E E AAE T A E O T E 175 2009 Thomson Reuters All rights reserved INTRODUCTION About the Healthcare Business of Thomson Reuters Thomson Reuters provides trusted medical information and flexible technology to provide clinicians access to answers alerts and recommendations This enables clinicians to enhance decisions prevent adverse events and promote the best clinical practices from diagnosis to aftercare In addition to serving the healthcare industry Thomson Reuters empowers professionals with unbiased pharmaceutical chemical and regulatory information With accurate answers to critical questions Thomson Reuters supports e Hospitals e Information System Providers e Pharmaceutical Companies e Managed Care Organizations e Environmental Health and Safety Organizations e Chemical Manufacturers With a full range of healthcare offerings covering drug disease patient education alternative medicine and toxicology Thomson Reu
182. pinephrine Dosing Calculator Adult Norepinephrine Dosing Calculator Pediatric Drug Classifications Antiarrhythmic Drug Classification Cephalosporin Generations Chemotherapy Acronyms A C Chemotherapy Acronyms D Z NSAID Classification Prostaglandin Synonyms Drug Comparisons ACE Inhibitors Beta blocker Comparison Calcium Antagonist Pharmacokinetics Calcium Antagonist Pharmacology Corticosteroid Potency Topical Dopamine Antagonists Parkinson s 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES DRUGS NSAID Pharmacokinetics Oral Antidiabetic Agents Radiopaque Agents Theophylline Content Salt Forms Thyroid Equivalent Doses Measurement Calculators and Conversions Body Weight amp Surface Area Calculator Body Mass Index Calculator Body Surface Area Body Weight Ideal Conversions Factors Equivalents Practical Metric Conversions Calculator Milliequivalents SIU Conversion Calculator Temperature Conversions TOXICOLOGY Antidote Dosing and Nomograms Alcohols Ethylene Glycol Blood Level Ethanol lV Dosing for Methanol Ethylene Glycol Overdose NAC Dosing for Acetaminophen Overdose Toxicity Nomograms Dosing Tools ACLS PALS Guidelines Dobutamine Dosing Calculator Dopamine Dosing Calculator
183. plement or condition entered as well as any synonyms associated with the term s For example Searching by name for the keyword red may yield the following results Search Path AltCareDex Alternative Medicine Education gt Narrow Results Search term red AltCareDex Alternative Medicine Education Results Titles 2 results RED CLOVER RED YEAST RICE Synonyms 10 results BLOODROOT CAPSICUM CURCUMIN DAN SHEN ELDER HORSERADISH POKEROOT POKEWEED ROOIBOS SLIPPERY ELM 2009 Thomson Reuters All rights reserved If the search term is found in the title of the document it will be shown on the Narrow Results under Best Matches See Red Clover Red Yeast Rice If the search term was found as a synonym for a document it will be listed under Synonyms See Bloodroot Capsicum etc PATIENT EDUCATION For example if you open the ROOIBOS document you will see the word red shown as bold text in the statement Other names for Rooibos include Aspalathus linearis Aspalathus contaminata Borbonia pinfolia Kaffree tea Psoralea linearis Red bush and Rooibos tea AltCareDex Alternative Medicine Education ROOIBOS What is it Rooibos is an herbal medicine sometimes used in the treatment of human immunodeficiency virus HIV infections and cancer Itis also used to prevent changes in the brain that occur with age Other names for Rooibos include Aspalathus linearis
184. pplied to names or synonyms for commercial and drug products plants and animals and to substance names slang terms or synonyms When searching for Product or Substance information the search results include product or substance names that begin with or contain the search term Tip When a search term is entered and no search type button is selected the Enter key is B used instead of clicking one of the search type buttons the search defaults to a ea Product or Substance search Search Product or Substance 1 Enter three or more characters in the search field Note Attempting to search on only one or two letters or numbers returns no search results This limit was implemented to prevent performance problems associated with retrieving extremely large result sets Wt The search term can be a e product name e substance name e synonym for a commercial or drug product plant or animal e synonym for generic product e slang term 2 Click the Product or Substance button or simply press the Enter key For information on Product or Substance search results see Product or Substance Search Results on page 70 Multiple Search Terms When a search phrase that contains more than one word is entered into the Search field the application looks for the entire phrase any place within the product or substance The search terms are not split apart all words in a search phrase must exist within the substance name
185. provide a convenient way to help patients better understand and participate in their treatment and care Documents can be customized with facility or clinician specific data Drug Information Documents Drug documents are patient oriented overviews of the most frequently prescribed drugs Medication use and warnings along with information about food and drugs to be avoided are clearly outlined in the documents Contain concise overviews of over 1 000 frequently prescribed drugs for distribution to patients Clinical Checklist The Clinical Checklist System is available to all subscribers of DISEASEDEX and is the must do never do database It is a compilation of the most pertinent patient care interventions on commonly encountered conditions that should always or never be done The interventions are presented as alerts within Healthcare Series The information is action oriented and concise and is based on nationally recognized quality standards and the highest rated medical evidence 2009 Thomson Reuters All rights reserved DATABASE DESCRIPTIONS Each checklist item contains graded recommendation and evidence information These evidence ratings embed evidence based medicine into clinical operations and ultimately maximize reimbursement by ensuring that clinical decisions are in compliance with the latest national quality standards and evidence based practices Clinical Xpert Much more than quick drug look ups Clin
186. quired Laboratory Values An array of calculators and references that complement the lab test workflow are available for your use Most of these tools just require you to select the calculator or reference from the list and then click the Go button The resulting report can be viewed or printed for your records or reference See Printing Documents on page 30 for more information on printing i Laboratory Values Creatinine Clearance Calculator Anion Gap Calculator Cerebrospinal Fluid Analysis Serum Chemistry Normal Values Phenytoin Level Adjustment Calculator Cholesterol and Triglycerides Synovial Fluid Analysis Creatinine Clearance Calculator Calculates creatinine clearance based on lean ideal body weight kg lb patient s age and sex Current serum creatinine level in mg dl and the initial therapy utilized Anion Gap Calculator Enter the sodium chloride bicarbonate and potassium levels to calculate anion gap Cerebrospinal Fluid Analysis Shows diagnosis based on test values Separate lists for adult and pediatric analysis Serum Chemistry Normal Values Lists normal lab values of serum chemistry panels Phenytoin Level Adjustment Calculator Utilized by clinicians to adjust reported serum phenytoin levels in patients that have low serum albumin levels or renal impairment Hypoalbuminemia and or renal impairment changes the binding affinity of phenytoin which results in a reported to
187. r rn Note Do not enter near and or or any other Boolean search operator even when searching more than one keyword at a time Compound keyword searches automatically perform a near search operation Every database contains thousands of documents covering medical concepts illnesses injuries procedures treatments protocols and drug information After typing the appropriate keyword press the Search button to start the search Matches based on the keyword s and your current subscription are displayed on a search results page grouped by major topic The major topics are e Summary Documents e Drug Information e Disease Information e Lab Information e Toxicology Information e Complementary and Alternative Medicine e Reproductive Risk Start by entering common terms diseases indications conditions drugs symptoms or side effects as in the following examples Diseases lymphocytic leukemia tuberculosis rheumatoid arthritis Drugs brand or generic names or classes of drugs taxol tenormin insulin ceclor cocaine tylenol analgesics verapamil nsaids Labs test name indication condition common panel name brand or generic drug serum cholesterol measurement cyanide exposure diabetes transplant panel prednisone Symptoms fever rash blindness memory loss Side effects incontinence vomiting angioedema Hazardous materials fertilizer sulfuric acid bleach clea
188. radiocontrast agents BEIUS nephrotic drugs and surgery 491 Renal impairment acute Renal insufficiency secondary to radiocontrast agents 8 aminoglycosides NSAIDs EZ atheroembolism and cardiovascular surgery 2lSlincreases the risk of acute renal failure Rhabdomyolysis Rhabdomyolysis can lead to both oliguric and nonoliguric renal failure and accounts for up to 10 to 15 of all acute renal failure ARF The presence of hypovolemia dehydration and acidic urine increase risk of ARF in the setting of rhabdomyolysis BSL e Rhabdomyolysis causes ARF by the following mechanisms S21 Adirect nephrotoxic effect of myoglobinernia on the tubular epithelium Muscle damage resulting in third spacing of fluids volume depletion and subsequent cast formation and luminal statis Muscle injury can lead to endotoxin cascade and subsequent renal vasoconstriction 2009 Thomson Reuters All rights reserved DISEASE INFORMATION Second level information includes links to references for this document Evidence ratings presented within the content give you confidence in determining the most appropriate test or treatment options for a patient ClinicalPoints Documents Summary Information The ClinicalPoints System provides brief highlights of treatment diagnosis and key information The ClinicalPoints System delivers answers quickly and efficiently and also provides links directly to additional or more in depth information foun
189. re tani ENAME DETERGENTS Orano Professional Stremath Punbing System Build U C Johnson United States 077314 QETERGENTS ANO SOAPS Bemover Cresey Liaukt ANIONIC AND NOMIONIC Ease drano Slana eem 113000 COCAINE BEROTONA SYNOROME chen Drano Drachet Products United States 077260 TRENLOROPTHANE Thichuned Focmuts Orano Cienr Linu Se Johnson Professional Canada 011209 CORROSIVE TALKALINE Products United States Product or Substance Search Results for DRANO 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION Search results are grouped into three areas Manufacturer Contact Information if found for the search term Synonyms and Product or Substance The table of search results for Product or Substance is shown expanded by default Other results can be viewed by expanding the accordion bar If more than one page of results are found navigate to additional pages using the page number link or First Previous or Last page links The Accordian Bar n Manufacturer Contact Information 17 Results Accordion bar u collapsed Synonyms 2513 Results expanded The accordion bar enables quick navigation to view grouped search results The list is expanded when the triangle is pointing down see Product or Substance in the previous example The list is collapsed when the triangle is pointing to the right see Manufacturer Contact Information and Synonyns in the previous example Sorting
190. re evaluated for Nitroglycerin 0 4 mg mLin D5W Dextrose 5 Dupont Pharmaceuticals Nitroglycerin more details Physical Compatibility Physically compatible No visible changes and no change in the measured haze level or particulates Storage Room 7 temperature of 23 A C exposed to fluorescent Reference 2109a Study Period 4 hours Method Visual observation and electronic measurement of haze and compatibility with the test drug light particulates 1 The peripheral line formula had the following composition per liter Aminosyn Il 3 5 Dextrose 5 Container Simulated Y site administration in glass test tubes Within each TPN TNA table the results are sorted alphabetically by TPN or TNA admixture name with the associated compatibility icon and description followed by high level notes on this test TPN TNA compatibility details for single drug compatibility searches are shown in a four column table e The first column contains the TPN or TNA name the compatibility icon and description delivery method and test Notes for the test if applicable shown in red text e The second column shows the drug name concentration and manufacturer s name e The third column displays the physical compatibility chemical stability if applicable and storage information e The fourth column contains a link to the reference the study period the study methods and the conta
191. rolling through the document e Print the assembled document minus screen buttons links miscellaneous navigation by clicking the File gt Print menu items from your Internet browser e Close the new window to return to the Print Setup page Print Selected Text Print Setup Printing Documents with Outlines Search Path Main Keyword Search gt Initial Results gt Document gt Print Setup CheckAll Uncheck All Overview C Dosing Information C Drug Properties C Storage and Stability Ml Adult Dosage Normal Dosage C Pediatric Dosage C Normal Dosage C Pharmacokinetics CI ADME O Elimination Half life Cautions O Contraindications C Precautions C Adverse Reactions C Dermatologic Effects C Gastrointestinal Effects C Neurologic Effects C Respiratory Effects C other C TeratogenicitwEffects in PregnancyBreastfeeding C Drug Interactions C Drug Drug Combinations E Drug Food Combinations C Clinical Applications C Monitoring Parameters O Place In Therapy C Mechanism of Action Pharmacology C Therapeutic Uses O Pain e Using your mouse click and drag to select the text you want to print e Click the File gt Print menu option or the Print button on your Internet browser toolbar Click OK 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES CALCULATORS ROMSEY MICROMEDEX Healthcare Series MICROMEDEX Mee ruas oxicology Disease Labs iV Compatibility Interactions
192. s Full Text Searches within Document Sections This type of search gives you the ability to create robust focused and specific searches Enter a search term then select the area or areas sections where the search should be focused For example You can search the Treatment section on the term Rash See Specific Topic Search on page 103 for step by step instructions Search by Healthcare Category This search gives you the ability to search by healthcare category allowing you to drill down to a definitive diagnosis See Browse Disease Categories on page 102 for more information on searching for disease content by healthcare category 2009 Thomson Reuters All rights reserved DISEASE INFORMATION SPECIFIC DATABASE SEARCH The Specific Database Search option allows you to search any or all of the databases to which you have a current subscription Searches can be customized to meet specific criteria The Specific Database Search page lists the databases available for inclusion exclusion in your search for disease information Search Options in the Database Search Three options are available to you on the Specific Database Search page Search by Keyword by LOINC code or search by ICD 9 code Disease Database Search Search for Keyword Search k vord Find all keywor Signs and Symptoms it d in an asterisk Wiah aceta for Begin With search LOINC Code Keyword Keyword se
193. s the molecular weight and valences Includes a table for milliequivalent weights for selected aqueous solutions Pediatric and Pregnancy Select the calculator then answer all questions for patient specific parameters or units of measure where prompted When all input is complete click the Submit button click Clear to remove all input and begin again Results can be viewed or printed See Printing Documents on page 30 for more information Apgar Score Pediatric Hypertension Pregnancy Risk Categories Vital Signs Pediatric Apgar Score Defines and describes the apgar scores Includes the five physical signs used to calculate the score the scores associated with the signs and the factors that influence the score Pediatric Hypertension Defines various blood pressures diastolic normal high high hypertensive and lists normal blood pressure levels for children 1 17 in the 90th 95th percentile Pregnancy Risk Categories Defines pregnancy risks by country for the United States Germany and Australia Vital Signs Pediatric Shows vital signs by age and the normal heart rate respiration and blood pressure 2009 Thomson Reuters All rights reserved 2009 Thomson Reuters All rights reserved CHAPTER 3 DRUG INFORMATION The number of drugs available today is enormous and the vast amount of information about these drugs can be mind boggling Use the Drugs tab to harness this information and give y
194. see Active Ingredient and Codes Search Results on page 74 a Note Although this search acts as a or contains search codes must be entered exactly as they exist All hyphens spaces letters numbers must be entered if they exist in the product code k WM For example Searching on EPA code 1332587 will not finda match for 1332 58 7 Searching 1332 5 will find a match for 1332 58 7 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION Product ID Enter a valid 7 digit POISINDEX product ID to retrieve that product with links to the full product entry Search Product ID 1 Type the full Product ID code in the Search field 2 Click the Product ID button For information on Product ID search results see Product ID Search Results on page 75 AAPCC Code Look Up Use this link to look up the definition of a specific code to find related codes or to browse the entire set of AAPCC codes 1 From the Toxicology tab select the Toxic Substance List option 2 Click the Look Up AAPCC Codes link 3 Type the AAPCC code number As you type the list jumps to the corresponding position in the list Look up AAPCC Codes AAPCC r AAAA Code 077 074000 CARDIAC GLYCOSIDES a 075000 PHENOTHIAZINES 076000 UNKNOWN TYPE OF LACRIMATOR 076570 CAPSICUM PEPPERS INCLUDE FOOD PRODUCTS HERE EXCLUDE 076571 LACRIMATORS DM 10 CHLORO 5 10 DIHYDROPHENARSAZINE 076572 LACRIMATORS
195. sion in your search for toxicology information All databases are selected by default Uncheck the databases you do not wish to include in your search Quickly de select uncheck all databases by clicking the Uncheck All link For an overview of each of the databases click the i information icon i to pop upa database definition e Type the complete drug product or substance if you are unsure of the spelling type the first few letters with the Begin With search option selected e Select the database s you wish to perform this search against e Click the Search button Toxicology Database Search Search Toxicology Databases for folic acid Search Find all keywords that Exactly Match End ia an asterisk iab aceta for Begin With search Begin With Search checked databases CheckAll Uncheck All REPRORISK System Li MSDS from Use Li Summary Documents fi POISINDEX Managements G TOMES System Li HAW Search results for only the databases selected are organized by content type and displayed as hypertext links Click the link most appropriate for your toxicology information question to view the document or document outline Exactly Match versus Begin With The default search method Find all keywords that Begin With uses the search term as the root term and expands on it You may also be familiar with the term wildcard search The Begin With searc
196. sition CO Complications C Algorithms CI Genetics C Related Information Medical History C References Findings Diagnostic Testing C Diagnosis oO Ongoing Assessment 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Search Results Document titles are displayed as a hypertext links Clicking a title link opens the document at the top beginning of the document Below the document title document sections where matches to the search terms were found are shown as links Clicking the section link opens the document directly at the chosen section A brief excerpt of text including the search term is displayed giving you context for the use of the term in that instance Search Path Disease Topic Search gt Search Results Showing Results 1 through 5 of 5 Your Search DVT 1 Deep venous thrombosis Acute Diagnostic Testing ected pelvic orca Ultrasound is the preferred test for the diagnosis of an Treatment lt DVT are to prevent propagation of the thrombosis decrease the likelihood Pulmonary embolism Acute Treatment for massive PE or extensive DVT a longer period of heparin or LMWH should be considered Sepsis Acute Treatment effect of deep vein thrombosis DVT prophylaxis specifically in septic patients prospective randomized trials showing the Atrial fibrillation Acute Treatment weight heparin LMWH at full DVT doses is suggested 19 Regardle
197. sitiulyiwixlylz T Alprazolam I Buspirone Hydrochloride I Chlordiazepoxide I Clonazepam I Clorazepate Dipotassium T Diazepam I Halazepam T Lorazepam I Meprobamate I Oxazepam The example above shows the drugs in the Antianxiety sub class in the Central Nervous System class You can view summary information for a drug by clicking the drug name link Compare Selected Drugs You can select any or all of the drugs on this page up to a maximum of 50 to view side by side comparisons Click the checkboxes to the left of the drug names you wish to compare then click the Compare Selected Drugs button See Compare Drug Summaries on page 43 for more information on viewing drug comparisons 2009 Thomson Reuters All rights reserved CHAPTER 4 TOXICOLOGY INFORMATION Accidental poisonings occur with even the most common and seemingly harmless substances In such situations having instant access to critical information can save lives Relied upon in 100 of U S poison control centers the POISINDEX System identifies ingredients for hundreds of thousands of commercial biological and pharmaceutical products The System links that information directly to management documents providing data on clinical effects range of toxicity and treatment protocols for exposure POISINDEX also delivers concise essential toxicology data on a single screen to ensure the fastest access to critical answers Treating patients unable
198. snsseasaeeeeececesesecessstsaeeeeseeesseceesseestnteesaueeeeesecesseeeneias 1 About the Healthcare Business of Thomson Reuters ooo cece ccsccecsseceeessececseseeeseeecssseeesseees 1 How to Contact Thomson ReUtel Se secre ieee itea ERE E E E EL EA E 3 What is Micromedex Healthcare S rieS oc cccccccccscccsssecccsseccccsseecesseeccesseccssseseneeeseseeseaes 4 What is the Thomson Reuters Editorial ProC SS cccccccccccseccessecessececsecesseeceseeceseeecesssensseecesssesseseesseeeees 4 About ATES NAL U cc Eee mee earns erea armen meen ne SE Pe ee nO ene Ore en oP Ie SC EEO 5 Chapter 1 Understanding the BaSics sccccssscccessssecccessscececssssceeeesssceees 7 Anatomy of the Healthcare Series PAGeS wosccccissecceeseesecscecsssusenesnoben siadehavabecneecvaetesiececeasieisnostnoesnes 7 TADS in kHealthicare SCM EOS vecccasssa etavive eeddicorentuettencta netsh autistic c EE es 8 IMAI EAA DE IEAA E A AE AERE E E A E E AA A a R O A 8 OEE E T A E E E E E A 8 MOXICOIOO Yesi saser sierras eE REA E furs ius EEEE SEANSEN EE EEEE AE AE staat NE EA EEE E EE E E E eet 8 DISS S ERE AE E E E oh E E E E E E R A E E E E E EE E 9 EE oA E A EAA A AAA N AE A EA E A AT e A S 9 V Compatibility sisine tts teneencrereneerettereeeprererreercersereteretce neiii Siri erpin nni nadi SEs EPE ER aiiin ananin 9 itera GULOINS aes NRE E EEE E A E EOE O TA 9 eaa E Beenaa E E A E E EE AE E E RE E E E E 10 LLLE EETA eE sues AEE E A A E S EA A A E Gevacenatstu
199. splays previous pages as links On the overview page it is displayed as Search Path IV Multiple Compatibility gt Clicking the IV Multiple Compatibility link takes you back one page to the Multiple Drug search page 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Start a New Search To search for compatibility information for a different set of drugs click the Modify Your Search button to return to the Multiple Drug Search page The Checking Compatibility For Links All of the drugs searched are shown as hypertext links Clicking a drug name link will open the solution overview page for a single drug compatibility result Y Site Overview Overview information for multiple drug Y Site compatibility is shown alphabetically by drug name with the associated compatibility icon and description e Click the drug name link to view the details of these tests Results are calculated and displayed for Y Site scenarios for the selected drug as both the primary and the secondary agent Admixture Overview Overview information for multiple drug admixture compatibility is shown alphabetically by drug name with the associated compatibility icon and description e Click the drug name link to view the details of these tests Syringe Overview Overview information for multiple drug syringe compatibility is shown alphabetically by drug name with the associated compatibility icon and description e Click the drug name li
200. ss whether cardioversion is Go directly to the Treatment section in the DISEASEDEX General Medicine document by clicking the Treatment link 2009 Thomson Reuters All rights reserved DISEASE INFORMATION Deep venous th bac Expand All Collapse All Background Definition Epidemiology Etiology Pathophysiology Complications History and Physical Summary Medical History Findings Diagnostic Testing Diagnostic Testing Summary Tests Diagnosis Differential Diagnosis Treatment Treatment Summary Drug Therapy Procedural Therapy Non Procedural Therapy Prognosis Disposition Admission Consultation Discharge Related Information Conditions Treatment Treatment Summary The management goals in treating DVT are to prevent propagation of the thrombosis decrease the likelihood of fragmentation and embolization of the blood clot and prevent the development of chronic venous insufficiency The mainstay of therapy for most patients with established venous thromboembolism VTE is anticoagulation therapy with unfractionated or low molecular weight heparin LMWH to hasten clinical stabilization and prevent recurrence Select patients with DVT can be treated on an outpatient basis or with early discharge to home Placement of a vena cava filter may be necessary in patients who have large clot burdens recurrent VTE despite adequate anticoagulation or contraindications to
201. st DISEASEDEX General Medicine Summary f Results 3 DISEASEDEX Emergency Medicine Acute renal failure Acute Summary Drug Information Titles amp Synonyms Click a link on the Initial Results page to view the titles types available Click a document title on the Narrow Results page to view brief and concise information on this topic 2009 Thomson Reuters All rights reserved DISEASE INFORMATION Search Path Document Acute renal ha By DISEASEDEX General Medicine Summary Collapse All Expand All Definition Medical History Findings Tests Disease Database Search gt Initial Results gt Narrow Results gt Acute renal failure Acute DISEASEDEX General Medicine Clinical Review Definition Differential Diagnosis Acute renal failure ARF encompasses several clinical syndromes characterized by a rapid Treatment decrease in the glomerular filtration rate GFR This results in the accumulation of various Drug Therapy nitrogenous waste products mainly blood urea nitrogen BUN and creatinine as well as an Procedural Therapy impairment of various other functions of the kidneys This decrease of GFR can occur either in i F previously normal kidneys or in patients known to have chronic kidney disease CKD The urine output during ARF varies widely and does not provide clinical correlation with the degree of the underlying kidney injury If itis less than 0 5 mi kg hour typica
202. t United States 254368 PAINT 1 Coat Paint Exterior Flat Acrylic Latex Dark Tone Pigmented Liquid Behr United States 254368 ETHYLENE GLYCOL PAINT 1 Coat Paint Exterior Flat Acrylic Latex Hi Hide White Pigmented Behr United States 254368 ETHYLENE GLYCOL Liquid PAINT 1 Coat Paint Exterior Flat Acrylic Latex Light Tone Pigmented Liquid Behr United States 254368 ETHYLENE GLYCOL PAINT 1 Coat Paint Exterior Flat Acrylic Latex Medium Tone Pigmented Behr United States 254368 ETHYLENE GLYCOL Liquid PAINT 4 Coat Paint Interior Exterior Glass Dark Tone Pigmented Liquid i Behr United States 254368 ETHYLENE GLYCOL aka 1 Coat Paint Gloss 100 Acrylic Latex Dark Tone PAINT 4 Coat Paint Interior Exterior Glass Hi Hide White Pigmented Liquid Behr United States 254368 ETHYLENE GLYCOL aka 1 Coat Paint Gloss 100 Acrylic Latex Hi Hide White PAINT 1 Coat Paint Interior Exterior Glass Light Tone Pigmented Liquid Behr United States 254368 5 ETHYLENE GLYCOL aka 1 Coat Paint Gloss 100 Acrylic Latex Light Tone PAINT ra RELAI Active Ingredient Latex Search Results Click the trade name link to view the Product List From the Product List page you can e view pertinent formulation information e click the lt Previous or Next gt buttons to move to the previous next product in the list of results e click the links for toxicologic managements for this product or substance to v
203. t effects are included in the Drug REAX System DRUG REAX System information is drug specific rather than class specific which helps to more accurately interpret interaction data The System program contains a dictionary of more than 8 000 unique drug terms and distinguishes between trade names and equivalent generic names eliminating possible duplication of interaction data on the screen Up to 128 concurrent clinical conflicts can be reviewed In addition the response speed of this database demonstrates no detectable degradation in data retrieval as the number of drugs being screened increases Formulary Advisor An easy to use electronic solution to manage your formulary An invaluable tool to help contain rising drug costs and promote patient safety Formulary Advisor gives you an effective tool to manage your hospital s formulary and provide immediate access to the formulary throughout your entire facility Accessible via desktop PCs and PDAs Personal Digital Assistants handheld computers Formulary Advisor helps guide prescribing clinicians toward formulary drugs saving your pharmacists nurses and physicians time and your facility money Formulary Advisor gives you and your clinicians real time point of care access to your formulary to promote formulary compliance Links to Micromedex Healthcare Series drug information are readily available providing dosing information drug interactions adverse effects contraindications and mor
204. t lists all the products databases and features in the Healthcare Series with a current subscription at your facility Also listed are the products and features not currently subscribed to but which are available by subscription for additional cost Page Help The Page Help icon and link opens the online help files specifically to the page or topic you are in at the moment For example if you were on the first page of the Multiple Interactions feature from the Interactions tab clicking the icon or link at the top right area opens help specific to searching for multiple interactions Footer Links 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Home Contact Us Content Updates Training Center Warranty and Disclaimer Editorial Info About Us Help Log Out Copyright 1974 2006 Thomson MICROMEDEX All rights reserved Information is for End User s use only and may not be sold redistributed or otherwise used for commercial purposes In addition to the basic search tabs Healthcare Series also offers some additional information help and navigation At the bottom of almost every page you will find hypertext links Click these links to find out what s new in this release to learn about training opportunities to find out more about Thomson Reuters and more Feel free to explore and become familiar with the information behind each link Home The Home page link is available from any page
205. t search you may want to narrow your search results using the Exactly Match method e Type your search term in the search term box e Click the Exactly Match option e Click the Search button The Exactly Match search considers matches only where the keywords exactly match a title synonym or index term character by character For example if the search term or keyword entered was epiglot the application does not find any documents containing epiglot as a keyword synonym or index term Change the search option to Begin With and the application finds several matches on epiglottitis If you search on the term opti with Find all keywords that Begin With selected the Healthcare Series application finds the following related index terms optic optica opticaine optical opticardon opticet opticlox opticorten opticortenol opticrom and many more All of the 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES documents listed on the various search results pages contain one or more of these indexed terms Change the selection for Find all keywords that to Exactly Match and perform the same search to yield matches for the keyword opti only Substantially fewer results will be returned on the search results page Main Keyword Search Search Drug Toxicology Disease and Labs databases for Search C Search summary documents only
206. t the entire lab document The Print Ready option prints the formatted document without the document outline any buttons tabs or navigational links 1 Click the Print Ready link at the top right corner of the document 2 Select File gt Print from your Internet browser menu 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES SEARCH BY SPECIFIC TOPIC Searching specific Lab Advisor topics performs a full text search on the search term within specified sections of a lab document Search Specific Lab Advisor Topics Search document for this exact term Search Within Check All Uncheck All CI Synonyms C Clinical Notes C Reference Range CI Contraindications C Indications Collection Storage Information C Common Panels C Test Definition C Drug Lab Interactions C Test Methodology C Abnormal Results C LOINC Codes E Test Complications C Related Information C References For example a nurse taking inventory notices they are getting low on EDTA tubes Before re ordering she searches Lab Advisor to see how many lab tests require the EDTA tubes for collection to give her a better idea of the number she should have in inventory 1 From the Lab Keyword Search page type the term exactly as it would appear in the lab document in the Search document for this exact term field In the example above the nurse would type EDTA 2 Select the outline sections that should be s
207. tal phenytoin level that is of little value clinically This calculator estimates what the total phenytoin level would be if the patient did not have these comorbid conditions Calculates the adjusted Phenytoin Level using current values for Phenytoin Level mcg mL Albumin gm dL and Creatinine Clearance mL min Cholesterol and Triglycerides 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Defines common cholesterol test terms such as LDL HDL and so on Includes normal ranges for adults and children with breakout information for Black White Males Females and Black White children Synovial Fluid Analysis Lists normal synovial fluid values and values by diagnosis such as acute gout rheumatoid arthritis etc Measurement Calculators and Conversions Most of these tools just require you to select the calculator or reference from the list and then click the Go button The resulting report can be viewed or printed for your records or reference See Printing Documents on page 30 for more information on printing nt Calculators and Body Weight amp Surface Area Calculator Body Mass Index Calculator Body Weight Ideal Conversion Factors Temperature Conversions SIU Conversion Calculator Equivalents Practical Metric Conversions Calculator Milliequivalents 4 W Body Weight amp Surface Area Calculator Calculates body surface area based on age years or mont
208. tensive information can be found for products manufactured in the United States Canada and United Kingdom MARTINDALE contains information on drugs in clinical use worldwide as well as selected investigational and veterinary drugs herbal medicines pharmaceutical excipients vitamins and nutritional agents vaccines radiopharmaceuticals contrast media and diagnostic agents medicinal gases drugs of abuse and recreational drugs toxic substances disinfectants and pesticides MARTINDALE is the electronic version of the highly respected MARTINDALE reference book published by the Pharmaceutical Press offering extensive unbiased evaluated information on worldwide drugs and related substances 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Trade Generic Drug List Search Results Healthcare Series searches the database selected for products matching the search term and returns a trade generic drug list The drug name form strength in some instances and manufacturer is listed for each match as a hypertext link Click the link to view the product information Search Path Trade Generic Drug List gt Tradename List Search DRUGDEX Tradename List Showing Results 1 through 10 of 10 DRUGDEX Tradename List for Aripiprazole om Showing Results 1 through 10 of 10 If multiple products were matched for example a DRUGDEX product search on phene would yield mat
209. teratogenic agents including chemicals food additives household products environmental pollutants pharmaceuticals and viruses e Includes research methods results and citations from both Japanese and Russian literature TERIS Teratogen Information System Developed by the University of Washington TERIS includes information such as the following e Current information on the teratogenic effects of drugs and environmental agents e Agent summaries derived from thorough literature reviews rate reproductive risk and explain data used to determine the rating 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES TOMES System Toxicology Occupational Medicine amp Environmental Series Healthcare professionals will find the TOMES database helpful when treating patients exposed to potentially toxic chemicals Detailed information for safely managing hazardous chemicals in the workplace is provided along with data needed for evaluating chemical exposures complying with government regulations and responding to emergencies involving hazardous materials What s in TOMES TOMES gives you information to handle both medical and environmental issues associated with virtually any chemical TOMES includes the following modules e MEDITEXT Medical Managements e HAZARDTEXT Hazard Managements MEDITEXT Medical Managements The medical information can help you evaluate issues associated with exposure Swallowed Skin
210. ters products enhance care at every stage in the hospital from diagnosis to aftercare e Patient History and Examination e Diagnostic Evaluation e Treatment and Medication Planning e Patient Education e Drug Administration e Treatment and Medication Monitoring e Discharge e Billing Claim Submittal e Patient Self care amp Follow up Thomson Reuters understands the important balance between content and technology Our internal force of clinical professionals is dedicated to the integrity of our information By verifying every detail they ensure the content is accurate up to date and clinically relevant This scrutiny instills confidence in clinicians who know they can trust Thomson Reuters beyond any other data In addition to offering products on today s preferred platforms Internet intranet and handheld we constantly look ahead to ensure our trusted information continues to be available when and where it is needed most That s why our current technology integration efforts with key information system vendors are focused on seamlessly delivering alerts and recommendations directly into our customers workflow 2009 Thomson Reuters All rights reserved 2 MICROMEDEX HEALTHCARE SERIES Thomson Reuters has a vision of changing the future of information by partnering with both our customers and the industry s top information system vendors Together we will permanently transform how information is used at health
211. the checkboxes click the Uncheck All link Once unchecked you can then select the topics you wish to search resent Note Disabled or dimmed database names denote a current subscription to the database was Ey not found Toxicology Topic Search Choose One Database to Search POISINDEX Managements O HAZARDTEXT MANAGEMENTS MEDITEXT MANAGEMENTS Search document for this exact term funnel web spider Search Within Check All Uncheck All O overview PharmacologyToxicology C Substances Included Synonyms Physicochemical O Clinical Effects C Animal Toxicology C Laboratory Monitoring C References Treatment Range of Toxicity C Kinetics 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Search Results Document titles are displayed as hypertext links Clicking a title link opens the document at the top beginning of the document Below the document title document sections topics where matches to the search terms were found are shown as links Clicking the section name link opens the document directly at the chosen section topic Search Path Toxicolgy Topic Search gt Search Results Showing Results 1 through 1 of 1 Your Search funnel web spider SPIDER FUNNEL WEBI PharmacologyToxicology MECHANISMASUMMARY The Sydney funnel web spider contains a lethal neurotoxin found in the venom Document Title Section Topic Range
212. the information Results can be viewed or printed See Printing Documents on page 30 for more information 2009 Thomson Reuters All rights reserved q Comparisons B ACE Inhibitors Theophylline Content Salt Forms Thyroid Equivalent Doses Corticosteroid Potency Topical Beta blocker Comparison NSAID Pharmacokinetics Calcium Antagonist Pharmacokinetics Calcium Antagonist Pharmacology Dopamine Agonists Parkinson s Oral Antidiabetic Agents Radiopaque Agents ACE Inhibitors Lists the name of the drug with onset peak and peak blood pressure ratios Theophylline Content Salt Forms Lists the substance and salt forms in percentages Thyroid Equivalent Doses Lists the preparation name and the approximate equivalent dosage Corticosteroid Potency Topical Lists corticosteroid drugs potency from very high potency to low potency Beta blocker Comparison A systemic Beta blocker comparison Displays information by substance regarding protein binding effects liver metabolization effects on renal function and the affect on lipid solubility NSAID Pharmacokinetics Lists the substance by name the percentage of protein binding the time to peak concentration half life renal excretion and percentage unchanged Calcium Antagonist Pharmacokinetics Lists the substance by name the peak and half life levels in hours percentage of protein binding and the chemical class Calcium Antagonists Pharma
213. therapy e Unknown unknown Documentation Ratings The amount and strength of documentation available for the interaction is also shown A complete legend of all documentation ratings is shown at the bottom of the page Hovering over the rating in the legend opens a pop up with the full definition The ratings and their definitions follow e Excellent controlled studies have clearly established the existence of the interaction e Good documentation strongly suggests the interactions exists but well controlled studies are lacking e Fair available documentation is poor but pharmacologic considerations lead clinicians to suspect the interaction exists or documentation is good for a pharmacologically similar drug e Unknown unknown Refine by RefineBy interactions for TES severity IED Documentation ED Three dropdown lists allow you to modify the interactions results to suit your needs 2009 Thomson Reuters All rights reserved DRUG INTERACTIONS 1 The Drugs dropdown allows you to remove any of the drugs previously selected from the interactions check De select uncheck any drug you wish to remove and then click the Update button 2 The Severity dropdown allows you to remove any of the interaction severities from the interaction results By default all severities are included To remove a severity de select it then click the Update button 3 By default all documentation types Excellent Go
214. tibility searches are shown in a five column table e The first column contains the drug name the concentration and the manufacturer s name 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e The second column shows the secondary agent name concentration and manufacturer s name e The third column lists the compatibility icon and description e The fourth column displays the physical compatibility chemical stability if applicable and storage information e The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination e Notes for the test if applicable are shown in red text at the top of the detailed study information In cases where the drug was not tested with the solution listed Compatibility Not Tested there is no link to further information Return to the Overview page by clicking the Back to Admixture Overview tab name link Syringe Details Syringe compatibility details for single drug compatibility searches are shown in a five column table e The first column contains the drug name the concentration and the manufacturer s name e The second column shows the secondary agent name concentration and manufacturer s name e The third column lists the compatibility icon and description e The fourth column displays the physical compatibility chemical stability if applicable and storage
215. tion in the document You may also scan the entire document by using the scrollbar When a document is opened the outline is shown in fully expanded state Click the Collapse All link to compress the outline to the first level of the outline Section names with a plus sign denote that additional sub sections exist below Click the section name with the plus sign to view the sub sections For more information on document outlines see Floating Document Outlines on page 27 BUPROPION back to top Expand All Collapse All Overview Dosing Information Drug Properties Storage and Stability Adult Dosage Pediatric Dosage Pharmacokinetics Onset and Duration Drug Concentration Levels ADME Cautions Contraindications Precautions Adverse Reactions Teratogenicity Effects in Pregnancy Breastfeeding Drug Interactions Clinical Applications Monitoring Parameters Patient Instructions Place In Therapy Mechanism of Action Pharmacology Therapeutic Uses Comparative Efficacy Evaluation With Other Therapies References 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES PRINT SETUP AND PRINT READY Two print options are available from within a document Print Ready and Print Setup Print Ready Page Help Search Path Drug Topic Search gt Search Results gt Document BUPROPION back to top Outline Print
216. toin Level Adjustment Calculator 39 Serum Chemistry Normal Values 39 Synovial Fluid Analysis 40 Measurement Calculators amp Conversions 40 Body Mass Index Calculator 40 Body Weight Ideal 40 Body Weight amp Surface Area Calculator 40 Conversion Factors 40 Equivalents Practical 41 Metric Conversions Calculator 41 Milliequivalents 41 SIU Conversion Calculator 40 2009 Thomson Reuters All rights reserved Temperature Conversions 40 Pediatric amp Pregnancy References Apgar Score 41 Pediatric Hypertension 41 Pregnancy Risk Categories 41 Vital Signs Pediatric 41 California Registry Number 68 CAM 141 CareNotes System 141 150 CAS number 68 Category List 142 143 Chronic 89 Clinical Checklist 20 Clinical References and Calculators 32 ClinicalPoints System 151 Compare Drug Summaries 43 change drugs in the display 45 change number of drugs to compare 44 display comparisons 44 Content Updates 14 CRN 68 Current Concepts Program 151 D DIOW 127 D5LR 127 D5NS 127 D5W 127 DSW 1 2 NS 127 Dietary Considerations and Guidelines 33 Differential Diagnosis 34 DIN code 68 Disclaimer 14 DISEASEDEX System ClinicalPoints 20 Emergency Medicine 101 152 General Medicine 100 153 document 27 outlines 27 outlines with a plus symbol 28 Documentation Ratings 139 Dosing Tools 34 Drug Classifications 36 Drug Comparisons 36 drug comparisons see Compare Drug Summaries Drug Information for the Consumer 152 drug interactio
217. ty is shown alphabetically by drug name with the associated compatibility icon and description e Click the drug name link to view the details of these tests Search Path IV Single Compatibility gt Compatibility Overview Modify Your Search Nitroglycerin more details Alatrofloxacin mesylate Compatible Insulin requiar Compatible Alfentanil hydrochloride i Isoproterenol f O compatible hydrochloride compatinte Allenlase ncompatibie Ketorolac tromethamine compatible Amikacin sulfate compatible Labetalol hydrochloride compatible Aruna O compatite Lactated Ringers i Injection Compatible Amiodarone hydrochloride Compatible Lansoprazole Results are calculated and displayed for Y Site scenarios for the selected drug as the primary and secondary agent Admixture Overview Overview information for single drug admixture compatibility is shown alphabetically by drug name with the associated compatibility icon and description e Click the drug name link to view the details of these tests Syringe Overview 2009 Thomson Reuters All rights reserved IV COMPATIBILITY Overview information for single drug syringe compatibility is shown alphabetically by drug name with the associated compatibility icon and description e Click the drug name link to view the details of these tests TPN TNA Overview Overview information for single drug TPN 2 in 1 tot
218. urer s name e The second column shows the secondary agent name concentration and manufacturer s name e The third column lists the compatibility icon and description e The fourth column displays the physical compatibility chemical stability if applicable and storage information e The fifth column contains a link to the reference the study period the study methods and the container information for this particular combination e Notes for the test if applicable are shown in red text at the top of the detailed study information Search Path IY Multiple Compatibility gt Compatibility Overview gt Compatibility Details Modify Your Search Checking Compatibility For Click on drug names to see single compatibility e Ampicillin sodium e Cefazolin sodium Y Site Detail Cefazolin Ampicillin sodium sodium 220 mgfmLin 80 mg mL in D5W Dextrose Sterile water for Notes Variable compatibility results have been reported for this combination depending on the infusion solution The incompatibility also occurred with the diluent alone 5 injection Physical Reference a incompativre Compatibility Physically Smith Kline amp Wyeth incompatible An Study Period 3 hours French Laboratories increase in measured turbidity particulates Method Spectrophotometric and or a color change measurement of haze or was detected turbidity and color changes Storage Room Contain
219. us next product in the list of results e click the links for toxicologic managements for this product or substance to view treatment and management information Click the POISINDEX Management link to view treatment and management information 2009 Thomson Reuters All rights reserved TOXICOLOGY INFORMATION DRUG IDENTIFICATION This feature is identical to Drug Identification on page 50 Drug identification tools were placed on both the Drug and Toxicology tab so it would be available and convenient to both workflows My Thomson Gate THOMSON i biechtte MICROMEDEX Healthcare Series Senin MICROMEDEX are Main Drugs i Labs IV Compatibility GESTE Patient Ed Formulary Handheld PDA Ei Subscription Details Page Help Search Path Drug Identificatio Imprint Code Description Colors Shape All Shapes Other Black than one color Blue Pattern Al Patterns Brown CTRL click to select more IDENTIDEX System Drug Images Database search Imprint Cade only search Imprint and or Description Search Clear 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES SPECIFIC DATABASE SEARCH When you know that the answer you are looking for is in a specific toxicology database you can refine your search by using the Specific Database Search option The Specific Database Search page lists the databases available for inclusion exclu
220. v dncocwcsurnvexcvarsvseewonesonsegudessdersdesecelucodacdedevetevetedecedsibveratevad EEEa 70 imprint Code Search Results sessiossa aie E a aN NE ESNE 73 Active Ingredient and Codes Search Results ssessessssesssesssrsrsestssrstisesestestsrstsestsststsestasintstsestaseseenesesst 74 PROGUEEID Se ahGliRESU IES usinis ao a naaa eap a aeae 75 Drug lAentineatiO Nesser ireen REE EE T E R E ERS 7J Spedice Bie ay cles 8 alg eee meee ten nean a E E E a A O 78 Databases included in the Toxicology Specific Database Search eececectecetteeneees 80 SPEGNE TOPIC SSA Gs cassettes tet r EE e AEA E EET 81 Document QUINE seeriana a rE a N EEEE 83 Print Setup and Print REAY eieiei aeien EEEE EERE TEE E 84 Chapter 5 Disease Information essssessseesseessseesssessseessseessseessseesseessseessseesee 85 2009 Thomson Reuters All rights reserved TABLE OF CONTENTS Enhanced DISEASEDEX Content and Navigation iecccccssssrasssessesscosccesecceeaveossveseeararonreosnsnvesanas 85 ClinicalPoints Documents Summary InformatiOn ccccccceccesceessessescssssesseseseeseesees 89 Acute Chronic Prevention amp Screening COCUMENTS ccccccseesceseeecseesseeeeseeeseeeseseeeseeeas 89 SU CIES Cr PVT Sesa R cd aut ees deesieeasee aan an N 90 TESS 62 POCO CS secre cater E E tone EAE EE 90 Clinical Checklist Documents Summary Information ccccecececeeccescesssessessssssseeneenees 91 Search by Keyword Signs and Symptoms LOI
221. velopment of these phenomena LEL Itis interesting that the locus coeruleus also contains a very high concentration of opiate receptors as well as adrenergic receptors l j tian of the signs and symptoms of narcotic withdrawal is that chronic administration of opiates produces a Breadcrumb navigation displays the current page s context within the Healthcare Series application The term breadcrumb is as in Hansel and Gretel leaving a trail of crumbs in order to find their way back out of the forest Jump back to any of the previous pages in the search by clicking the hypertext link name 2009 Thomson Reuters All rights reserved UNDERSTANDING THE BASICS Search Path Main Keyword Search gt Initial Results gt Narrow Results gt Summary Document Search Path Calculators gt Alcohols Ethylene Glycol Blood Level gt Alcohols Ethylene Glycol Blood Level Results Search Path Compare Drug Summaries gt Search Results gt Document Comparison Search Path IV Multiple Compatibility gt Compatibility Overview gt Compatibility Overview Sample Breadcrumbs Calculators Calculators The Calculators icon and link opens the same calculators page as is available from the Main tab Calculators menu item Use this shortcut to access commonly used calculators dosing tools nomograms and clinical references Subscription Details Ej Subscription Details The Subscription Details icon and link opens a new window tha
222. vetacssasatieaite 10 kondheldi PDA aene a E E rE E E AE E N E E E EO 10 Evidence Xpert The Point of Care Interface ccccsscsssessssscesseesececeesceseceeseesesssesseesaeees TI Mis ellane us Naviga tiom esmesi rin iE a AATE ERREEN E EARE 12 Chapter 2 MGI sicccsccisssscacsacscs shed celccosahacaccaceaslacaddedeaidasdexacadadanesdecsisacsaseenoceacecs 17 Main IP IG saccmeeceatcsiaesacente as nansendainiusnshlaxexqiceee REE RE EE E AE ARE EEEE 17 keyword SEAC kesese anra e den loubebiceenvncsssddledGvcbed aa T Search Summary DOCUMENTS cis icstevstecececared ecauedeatencdatasecereastnst Na E AEE A E E EEY 20 Select DataHaSE Suaresni daian o upana aa aean ia N ATERRO AEA EEA n Enia n o an 21 Multiple KEY WONS cessisse sosisini eieiei naa e EE EEE K EEE E E EE E EEE 22 SEACH WIEMES VMOMYINIS ieem a a E E AE E E S EE 23 Expanding Search KeyWord Sirrini inoseni a i iiei eaa E EE E S e ies 23 Searc M RESUS eesin ev N EN E E E E ON RE 23 mittal RESES arrera ai AE E ed dus AEE E tenets A EEA A EES 23 Narrow Re SUES 5 sn csscesmstanst ancbazetetoseduuntansalnas abaviesansunaiitoianates ates at deesuiatiodsine a A ENAS 26 Modify Yo r SCANGH sic ccisecvcccscadeapcaceassencashgudtes doandadeateabeereacedopdanscnobetaancudesteusbeaseducsdduseautes EE E 2 DOCUMEN Sn Yee ysieeveddeccck ovecenssadaseiecaterebit tila avdeddas E E rece 27 Floating Document OUt MINES ersen narra EEEE EE A A ETAR ATERATEN EEEE EEES 27 Document Outlines with or F
223. was found in the title of the document e Synonyms The search term was found to be a common synonym for a document e Related Terms The search term was not found in the title or synonym of a document but it was found within a section such as indications drug lab interactions etc of a document Brand Names The search term was found as a brand or generic drug name somewhere in the document For example a search on the term acid may result in the Narrow Results page shown at left Clicking a link opens the corresponding lab test document Select the test you are interested in from the list on the Narrow Results page 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Search Path Lab Database Search gt Narrow Results Search term acid Lab Advisor Results Titles 21 results 5 Hydroxyindoleacetic acid measurement Acid fast stain method Nocardia species Acid fast stain method Parasite Acid mucopolysaccharides measurement quantitative ni i I i vel Chlamydia trachomatis nucleic acid amplification test hl ia tr lei ji idizati Cytomegalovirus nucleic acid assay Folic acid measurement RBC Hepatitis C nucleic acid assay Qualitative Hepatitis C nucleic acid assay Quantitative Lactic acid measurement Lysergic acid diethylamide measurement Microscopy acid fast bacilli Neisseria gonorrheae nucleic acid amplification test Neisseria qonorrh
224. will find the web address and Customer Number necessary to register and download Clinical Xpert Once registered as a Clinical Xpert customer when new or updated content becomes available you will automatically receive it when you sync your handheld device 2009 Thomson Reuters All rights reserved APPENDIX A DATABASE DESCRIPTIONS Thomson Reuters publishes clinical decision support databases and tools The Micromedex Healthcare Series provides a wide range of databases tailored to meet the needs of clinicians and healthcare professionals including information related to drugs acute care toxicology complementary and alternative medicine and patient education MICROMEDEX HEALTHCARE SERIES DATABASES AltCareDex System AltMedDex System AltMedDex Protocols AltMedDex Points System AltMed REAX for the Patient CareNotes System Clinical Checklist Clinical Xpert ClinicalPoints System Current Concepts program Detailed Drug Information for the Consumer Diagnostic amp Therapeutic Pearls Differential Diagnostic Lists DISEASEDEX General Medicine DISEASEDEX Emergency Medicine DISEASEDEX Clinical Reviews DISEASEDEX Prehospital Care Pro tocols DRUGDEX System DrugPoints System DRUG REAX System Formulary Advisor Herbal Medicines A Guide for Health Care Professionals IDENTIDEX System Index Nominum IV INDEX System with Trissel s Tables Lab Advisor
225. written and reviewed by authorities in the field of herbal and dietary supplement interactions What s in AltMed REAX for the Patient e Herb Dietary Supplement drug interactions e Herb Dietary Supplement dietary supplement interactions 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES e Herb Dietary Supplement alcohol interactions e Herb Dietary Supplement food interactions For each type of interaction the following information is given e General information on interactions e Symptoms indicating that a harmful interaction has occurred e The effects of the interactions Supporting evidence for the interaction e Instructions on actions the patient should take e References The CareNotes System Education for the Patient Patient education documents to assist healthcare professionals in educating patients about their immediate condition treatment follow up care and continuing health concerns Documents cover a wide range of subjects including cardiovascular and thoracic surgery dental and oral surgery OB GYN infectious diseases pediatrics gastroenterology and respiratory concerns The documents offer the necessary patient centered medical information to help improve care and achieve the most successful outcomes What s in CareNotes e Care and Condition documents e Drug information documents Care and Condition Documents Written at a 4th to 6th grade reading level these documents
226. y AH American Healthways NQF National Quality Forum HEDIS Health Plan Employer Data and Information Set Searching by Performance Measure 2009 Thomson Reuters All rights reserved Clinic MICROMEDEX HEALTHCARE SERIES al Checklist Related Terms jeaho isin Clinical Checklist under these topics e quality standards 6 results quality standards 6 results Acute coronary syndrome Acute JCAHO Aspiration pneumonia Acute JCAHO Community acquired pneumonia Acute JCAHO Heart failure Acute JCAHO Heart failure Chronic JCAHO Violent behavior Acute JCAHO Quality Mangers Medical Librarians Nurse Managers and other clinicians may find a search by the organization useful Simply type the organization abbreviation see above as the search term in a Main gt Keyword Search or Disease gt Specific Database gt Keyword search For example a search with JCAHO as the search term quality standard currently returns six Clinic al Checklist documents Also displayed in Clinical Checklist documents are links to related information for this topic such as DrugPoints documents other additional Clinical Checklist documents ClinicalPoints documents Lab Advisor documents ToxPoints documents PreHospital Care Protocol documents Studies amp Alerts All information is fully referenced and citation information is listed at the bottom of each document Links
227. y information for a different drug click the Modify Your Search button to return to the Single Drug Search page The more details Link A more details link is placed next to the drug name at the top of the page Click this link to jump to the bottom of the page to view summary information for the drug such as Trade Names and pH Range Jumps to bottom of the page to view Search Path IV Single Compatibility gt Trade Names Other Names pH Range Compatibility Overview Start a new single _Modify Your Search Nitroglyceri N more details drug compatibility search Solution Y Site dmixture Syringe TPNTNA Common Solutions Compatibility _ Other Solutions Compatibility en 5 caution Variable Lactated Ringers Injection Compatible D10 Sodium lactate 1 6 M i Click a link to view Dextrose 10 B not testea e cNy O compatinie _ detailed test results i B DSLR Dextrose 5 in lactated v Compatible DS5NS J Dextrose 5 in sodium compativie chloride 0 996 DSW 1 2 NS Dextrose 5 in sodium Compatible chloride 0 45 NS 4 Normal saline Sodium caution Variable chloride 0 9 12 NS j Sodium chloride 0 45 compativie Compatibility Key Key Compatible A Caution Variable Incompatible Uncertain i Not Tested Nitroglycerin Trade Names None listed Other Names None listed pH Range
228. y require you to select the tool by name and click the Go button The resulting report can be viewed or printed for your records or reference See Printing Documents on page 30 for more information on printing The Differential Diagnosis tools are shown in alphabetical order from the dropdown and list a diagnosis with a differential diagnosis For example Chest Pain can also be a Cardiovascular Disorder a Gastrointestinal Disorder or a Musculoskeletal Disorder Differential Diagnosis A C Differential Diagnosis D G Differential Diagnosis Ha Hm Differential Diagnosis Hn Hz Differential Diagnosis O Differential Diagnosis P R Differential Diagnosis S T Differential Diagnosis U Z Dosing Tools Select the calculator then answer all questions where prompted When all parameters have been input click the Submit button click Clear to remove all input and begin again 2009 Thomson Reuters All rights reserved Results can be viewed or printed See Printing Documents on page 30 for more information ACLS PALS Guidelines Dobutamine Dosing Calculator Dopamine Dosing Calculator Epinephrine Dosing Calculator Adult Epinephrine Dosing Calculator Pediatric Heparin Dosing Calculator Iv Rate Calculator Nitroglycerin Dosing Calculator Nitroprusside Dosing Calculator Norepinephrine Dosing Calculator Adult Norepinephrine Dosing Calculator Pediatric ACLS PALS Guidelines Based
229. zirnis eiiiai 28 PUTER DOCUMEN Saenen ae a E E EE EE A EE E 30 Print from the BrOWS Cl orreri aen E E e ETER 30 Print Ready Printing documents without Outlines ssssssssessississsnssnisrissrinrinrrrerrsreern 30 Print Setup Printing Documents with Outlines wiicicssisscsssassrescecaceseccseeviveanreevaieneanennasarunarins 31 Print Selected TEX niaii E a a E e iN 31 CCM a e rE e E E E E sees esucucees 32 2009 Thomson Reuters All rights reserved MICROMEDEX HEALTHCARE SERIES Antidote Dosmg and INOMOGI SIS i ccs sccscesvederceecerapeserasoravisnsbvannasitaadaanniveaeieiandoneneesaniions 32 Clinical References and Calculatol Smansa iii 32 Dietary Considerations and Guidelines a2sccccscevcccchansntsctvosascastdenssacadedeiecacacestvietspansuensseseneseaes 33 Dimerentiat Diagnosi Sts O E n ENE 34 D sinNg lOO Seeonee e TEE EE e E E 34 Brug Compa SoN Sss EE T N E E T 36 Immunizations amp PO VIANIS ci cccccee siiasd cisarddnctaccxtdeatdseddeebiceencaeeunnddtcdlsd seasesdecdgsdienluesnenseenstes 38 Laborato Valle se pra aceracesrserea nesses ade dendacceeuranucaetansivasanie savas dassacosestaaticinieubselancesaevennies 39 Measurement Calculators ANd Conversions ccccccccccesseeseeecsseesseeeseceeseeessesesseeceeeesseessees 40 Pediaticand PrEgNANGY sorsrterrerrarenes eae SASE O NEETA RE EEEE AAO EE EErEE E Al Chapter 3 Drug Information seeseesooseeseossecesessecessesccsssesossseecossecesssecessesoos 43 Compare Drug S

HCSO User Guide.book

Contents

Download Pdf Manuals

Related Search

Related Contents