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1. complete dose It is possible to set a dose larger than the amount of insulin left in the cartridge At the end of an injection the number in the window should be O If it is not this is the amount of insulin you did NOT receive Remember this number Remove the needle and the empty cartridge Insert a new cartridge as shown in 1 and prime the pen as shown in 2 Complete your dose by injecting only the amount you did not receive Dose Dose Window Knob Pen Injection Body Button Inspect Insulin Be sure to check your insulin for e Type e Expiration date e Appearance Wipe the small rubber seal on the end of the cartridge with an alcohol swab Push injection button and hold for 5 seconds Look for a stream of insulin The pen is NOT properly primed if you only see a few drops of insulin Replace Needle Outer Cap ek Carefully replace the outer Cap as instructed by your healthcare professional To prevent air from entering the cartridge do not store the pen witha needle attached Pen Needle sold separately Needle For Cloudy Insulin Only ars Roll the pen gently 10 times J R i and invert the pen 10 times The insulin should look evenly mixed If No Stream Is Seen Repeat Priming Dial 2 units Tap cartridge Push injection button and look for stream Remove the capped needle by twisting it off Throw away as directed by your he
2. PV5830AMP 4P2V1 2 23 07 10 03 AM Page 1 PV 5830 AMP Oh e ow LUXURA HD INSULIN DELIVERY a USER MANUAL For use only with Lilly 3 mL Insulin Cartridges 100 IU mL Your HumaPen LUXURA HD may be a different color from the one shown but it will work in the same way Ry only Lilt HumaPen LUXURA HD Pen Parts Pen Needle sold separately Cartridge Lilly 3mL Insulin Dose Dose Screw Window Knob Holder Cartridge sold separately Rubber Cartridge Pen Injection Needle Seal Plunger Body Button HumaPen LUXURA HD is designed for ease of use You can inject from 1 to 30 units of Lilly insulin from a 3 mL cartridge 100 IU mL You can dial your dose one half 1 2 unit at a time If you dial too many units you can correct the dose without wasting any insulin INSERT THE INSULIN CARTRIDGE Important Notes e Your healthcare professional has prescribed the type of insulin best for you Any changes in insulin should be made only under medical supervision e HumaPen LUXURA HD is for use only with Lilly 3 mL insulin cartridges e Do not use other brands of insulin cartridges e Read and follow the instructions provided in your Lilly 3 mL insulin cartridge Information for the Patient e Before each injection read the cartridge label and be sure the pen contains the correct Lilly 3 mL insulin cartridge e The color of the pen is not intended to indicate insulin type e HumaPen LUXURA HD is not recomme
3. correct the dose by dialing backwards Insert Cartridge i i Insert small end of 3 mL insulin cartridge into the cartridge holder Before inserting check the insulin cartridge to make sure it is not cracked or broken Pull off the outer cap and the inner cap Keep the outer cap to remove the needle after your injection Inject Your Dose LUXURA HD INSULIN DELIVERY DEVICE Rubber Seal Cartridge Holder Cartridge Screw Plunger P p T F om i ey Lilly 3 mL Insulin Cartridge sold separately HumaPen LUXURA HD Pen Parts Push Screw Back e The screw may be in or out when you get the pen e If the screw is out use the cartridge plunger to push the screw back If you push the injection button without a cartridge in the cartridge holder the screw will not move forward Tap Cartridge Point pen up Tap cartridge to collect air at the top for removal Attach Cartridge Holder Push the cartridge holder and pen body straight together Screw the pen body onto the cartridge holder until it is secure Prime The Pen Insert the needle as directed by your healthcare professional Place your thumb on the injection button then slowly and firmly push the button until it stops moving a 5 seconds Continue to hold the button for 5 seconds then remove the needle from your skin Check to make sure you see a 0 in the dose window to confirm you received the
4. Injecting Why is it difficult to push the injection button when I try to inject Your needle may be clogged Try attaching a new needle and then prime the pen Pushing the injection button down quickly may make the button harder to push Pushing the button more slowly may make it easier Using a larger diameter needle will make it easier to push the injection button during injection Ask your healthcare professional which needle is best for you If none of the above steps resolves the problem your pen may need to be replaced Your injection button may become harder to push if the inside of your pen gets dirty with insulin food drink or other materials Following the CARE AND STORAGE instructions below should prevent this 2 Why doesn t the dose knob go to zero when inject my dose This can happen if the insulin cartridge does not have enough insulin left in it for your entire dose The number in the dose window is the amount you did NOT receive To get the rest of your dose remove the needle change the insulin cartridge attach a new needle and prime the pen Then complete your dose by dialing the amount that you did NOT receive and inject only this amount CANE AND STORAGE Remove the needle after every use Do not store the pen with the needle attached Keep the pen away from moisture dust extreme hot or cold temperatures and direct sunlight Do not store the pen in a refrigerator Wipe the pen cap pen body a
5. althcare professional Replace Cap If you have any questions or problems with your HumaPen LUXURA HD contact Lilly at 1 800 LillyRx 1 800 545 5979 or your healthcare professional for assistance PV 5830 AMP Literature issued November 11 2006 Manufactured for Eli Lilly and Company Pharmaceutical Delivery Systems Lilly Corporate Center Indianapolis IN 46285 USA Authorized Representative in the EU Eli Lilly and Company Ltd Erl Wood Manor Windlesham Surrey GU20 6PH UK Humalog insulin lispro injection rDNA origin HumaPen and HumaPen LUXURA HD are trademarks of Eli Lilly and Company Patents pending for HumaPen LUXURA HD Copyright 2006 Eli Lilly and Company All rights reserved
6. btain a replacement 4 What should I do if have an air bubble in the cartridge Priming your pen will remove air Point the pen up and tap the cartridge gently with your finger so any air bubbles can collect near the top Repeat the priming steps until a stream of insulin is seen A small air bubble may remain in the cartridge after completion of the priming steps If you have properly primed the pen this small air bubble will not affect your insulin dose REPLACEMENT Your HumaPen LUXURA HD has been designed to be used for up to 3 years after first use Record the date your pen was first used here _ Contact your healthcare professional to get a prescription for a new HumaPen LUXURA HD when your pen has been used for 3 years If you have any questions or problems with your HumaPen LUXURA HD contact Lilly at 1 800 LillyRx 1 800 545 5979 or your healthcare professional for assistance PV5830AMP 4P2V1 2 23 07 10 06 AM Page 2 Getting Ready Wash your hands and make sure you have the following items before beginning e HumaPen LUXURA HD e Lilly 3 mL Insulin Cartridge e New Pen Needle e Alcohol Swab Pen Cap 1 INSERT THE INSULIN CARTRIDGE Pull Off Cap Unscrew Cartridge Holder Remove Paper Tab 4 Attach Needle Screw needle straight onto the cartridge holder Turn dose knob to your desired dose Example 51 2 units shown in the drawing above If you dial too many units you can
7. idge plunger Once the end of the screw pushes the cartridge plunger out insulin will flow from the needle Before Priming After Priming Cartridge Plunger Gap Screw No Gap Between Screw and Cartridge Plunger Repeat the priming steps until a stream of insulin is seen If you are still unable to see a stream of insulin flow from the needle go to Question 3 3 Why should I prime to a stream and why isn t the pen ready for use if see a drop of insulin on the needle tip Priming moves the screw into contact with the cartridge plunger and gets the air out of the cartridge When you are priming the pen You may see a drop of insulin on the tip of the needle when you first attach it This only shows that the needle is attached and not clogged You must still prime the pen You may also see no flow at all This may be because the screw is moving forward to close a gap between the screw and the cartridge plunger If there is air in the cartridge the insulin may sputter or drip until all the air is removed Insulin will flow as a stream only when the pen is properly primed If the injection button is hard to push the needle may be clogged Attach a new needle Repeat the priming steps until a stream of insulin is seen If you are still unable to see a stream of insulin out of the needle do NOT use the pen Contact Lilly at 1 800 LillyRx 1 800 545 5979 or your healthcare professional for assistance or to o
8. nd case with a damp cloth to clean them Do not use alcohol hydrogen peroxide or bleach on the pen body or dose window Also do not cover in liquid or apply lubrication such as oil as this could damage the pen Refer to the insulin cartridge Information for the Patient for complete insulin storage instructions BEFORE EVERY Y INJECTION PRIN IN AE TH E PEN Important Notes e HumaPen LUXURA HD is suitable for use with Becton Dickinson and Company pen needles e Do not share your pen or used needles e The directions regarding needle handling are not intended to replace local healthcare professional or institutional policies e Use a new needle for each injection This will help ensure sterility It will also help prevent leakage of insulin keep out air bubbles and reduce needle clogs Frequently Asked Questions about Priming h Why is it important to prime before every injection If you do NOT prime you may get too much or too little insulin Priming helps to ensure that the pen and needle are working properly Once the pen is properly primed a stream of insulin will flow from the needle You may need to prime several times before you see a stream of insulin 2 Why can it take several attempts to prime when a new cartridge is inserted There may be a gap between the screw and the cartridge plunger Repeating the priming steps will move the screw out to touch the cartr
9. nded for the blind or visually impaired without the assistance of a sighted individual trained to use it e Always carry a spare insulin delivery device in case your pen is lost or damaged e The numbers on the cartridge holder give an estimate of the amount of insulin remaining in the cartridge Do not use these numbers for measuring an insulin dose e For more information on HumaPen LUXURA HD and Lilly insulin please visit our website at www Humalog com pele insulin lispro injection rDNA origin Frequently Asked Questions about Inserting the Insulin Cartridge h Why doesn t the screw move out when there is no cartridge in the pen The screw may not move out when you push the injection button unless there is a cartridge in the pen This feature of the pen allows you to easily push the screw into the pen body when replacing a cartridge Once a cartridge is inserted the screw will move out when the injection button is pushed 2 What should I do if can t attach the cartridge holder to the pen body Check that the insulin cartridge is fully inserted into the cartridge holder Then carefully line up the cartridge holder with the pen body and screw together until secure 3 a Important Notes e You must PUSH the injection button straight down for the dose to be delivered e You will NOT receive your insulin by turning the dose knob e Do not attempt to change the dose while injecting Frequently Asked Questions about

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