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TrichoSciencePro v1.3SE User Manual

1. f Professional hair and scalp diagnostic software Chapter 14 Trichogram TTICNOSCI Pro l Ga LrichosciencePro module e Chapter 14 Trichogram module After entering New patient 1 1 Fig 1 information 1 2 and filling out the Outpatient card data 1 3 in order to proceed with the diagnostic session click Trichogram module button 1 22 The Trichogram diagnostic session window 14 0 Fig 14 will open If the patient has been entered into the program already select the patients name from Patient s name list 1 15 and proceed to the diagnostic session e 14 1 Conducting the Trichogram session In the opened Trichogram diagnostic session window 14 0 Fig 14 press the Scan icon 14 12 the image capture window will open Usually left window is used for Parietal area and right window for Occipital area study Place the Diagnosis Scope lens on epilated hair root s extracted from patient s scalp and position the mouse cursor within image capture window Trichogram study typically requires about 50 hairs to be epilated After good quality image is obtained lock it by pressing left mouse button Click OK and the picture will appear in the corresponding window Use the block of 7 hair type icons 14 1 to mark up hair roots in the field of view By placing mouse cursor over each of these icons you will have their names displayed This gro
2. TrichoSciencePro y1 1SE l ox Patients Performed Trichascopies Patient s name Date 03 02 2012 20 25 40 Trichoscopy Bob Johnson 04 02 2012 10 31 15 Mary Smyth 04 02 2012 9 26 53 Phototrichagram Trichogram 16 10 Detmatoscopy 16 0 Hair calculator Patient Mary Smyth x iss Terminal hair density in Parietal area sq cm total 121 lt lt Trichometry hair wash test Patient Mary Smyth Vellus hair density in Parietal area sq cm total 113 Terminal hair density in Occipital area sq cm total 251 Vellus hair density in Occipital area sq cm total 112 g3 Total Telogen hair in Parietal area 2466 0 Filin Hair quantity column value Total Anageni hex in Parietal area 75 34 Hai length Hair quantity Percentage of hair Vellus among Telogen in Parietal area 66 67 Under 3 om Goa CA Total Telogen hair in Occipital area 235300 peat 7647 Over 5 cm 16 1 Total Anagen hair in Occipital area Total hair shedded Vellus among Telogen in Occipital area 12 50 Sex CM F 23 Trichometry hair wash test 2 f tose 16 2 Age i oie ge _h EE Racial variations of hair 16 4 European Caucasian Date of hair sampling Ea Total mean quantity of scalp hair population norms 100 000 70 000 130 000 Fill out Hair total column Total actual quantity of scalp hair 115548 11600 Total actual quantity of Terminal hair 72000 7200 Ha
3. function After completing all diagnostic sessions and studies as well as generating conclusions and reports for the patient in order to proceed click Summary report function button 1 30 Fig 1 When prompted 21 0 to select components for the report choose the items you want to be included into report i e Trichoscopy Phototrichogram Trichogram Dermatoscopy Hair calculator Hospital Anxiety and Depression Scale Additional Studies Conclusions www TrichoSciencePro com 2 Professional hair and scalp diagnostic software Chapter 21 Summary report ichoSciencePro CA and Recommendations Automatic Conclusion 21 1 When finished click OK 21 2 The Summary report will be generated as MS Word document file NOTE Summary report may include any patient images stored in Additional Studies folder on the desktop To do this click Additional Studies button 1 26 locate and open images that you plan to include into report Place the cursor within the open image field right click the mouse and select To report when prompted The image will be stored within the report and will remain in it anytime the new Summary report is generated _ TrichoSciencePro v1 1SE BAE Patient s name Performed Trichoscopies Patient name Date 2 3 2012 8 25 40 PM Trichoscopy Bob Johnson 2 4 2012 10 31 15 AM Mary Smyth 2 4 2012 9 26 53 AM Photot
4. www TrichoSciencePro com ich O S E ji ence P ro measurements and calculations Follicular unit counts e Professional hair and scalp diagnostic software Chapter 4 Hair density and diameter The first two methods are being used together mostly and efficiently compliment each other to deliver quick and most complete assessment of hair density and their diameters as well as adding to it per user choice information on their distribution per follicular units and perifollicular sign counts Both methods allow to establish hair counts per sq cm with their diameter measurements and calculations including mean diameter of all of hairs Terminal and Velus hair counts mean diameter of Terminal hairs only with a percentage of thin medium and thick hairs coefficient of Anisotrichosis etc s The third method is just for density count with estimation of Terminal and Vellus hairs per sq cm while disregarding their diameters performed only in manual mode The separate follicular unit count method is not just another way of density calculations it actually compliments all three methods above and is designated to estimate the number of both Terminal and Vellus hairs per sq cm per their distribution in the follicular units NOTE To make it more convenient and accurate when counting hairs in the left image window for Parietal area the size of this window can be increased To do this grab and drag with the mouse the separating
5. Professional hair and scalp diagnostic software TrichoSciencePro www TrichoSciencePro com tel loYortsselesd nek Zs Professional hair and scalp diagnostic software ins 5 11 51 56 78 12 36 70 78 50 45 85 34 1275 78 22 56 78 90 63 83 31 28 12 TrichoScienceProo Professional hair and scalp diagnostic software USER MANUAL How to install use and administer TrichoSciencePro software The information in this document is subject to change without notice and should not be construed as a commitment by TRILOGIC LLC TRILOGIC LLC assumes no responsibility for any errors that may appear in this manual This document or any part thereof may not be reproduced in any form without the written permission of TRILOGIC LLC TrichoSciencePro logo and marks are the property of TRILOGIC LLC or a related company All rights reserved Copyright 2015 TRU GIC www TrichoSciencePro com 2 Professional hair and scalp diagnostic software Table of Contents ESON a A a O e Table of Contents e Chapter 1 TrichoSciencePro software installation 6 1 1 Personal computer hardware other software and network requirements 6 e Chapter 2 Introduction to Program Manager interface Patients module 6 2 1 Patient data management and transfer to another computer 7 e Chapter 3 Trichoscopy module 9 3 1 Getting started Image acquirement 9 e 3 2 Select video capture device fu
6. module E The separate Express Trichoscopy module 1 27 Fig 1 of the program is dedicated to the express diagnostic sessions that are performed when time devoted to each patient or client is limited while quick but efficient evaluation is of a main importance The settings and functions of this module are absolutely identical to Trichoscopy module 1 20 above However the main difference is that this module operates in a standalone mode There is no requirement to enter any patient data also no session data is saved automatically by default However if necessary any performed session actions and data may be saved by user into a separate picture file and printed out g Express Trichoscopy Start session 8 26 2015 10 47 28 AM one S Hair density Hair diameter Scalp analysis Hair roots analysis Hair shafts analysis Conclusion Print results Ba Fe aC r Base aoe e ia x Ca 7 amp RA Mg 4 KEER EOF EER FORE alel S 18 75sq mm_ Threshold for Terminal Vellus hair diameter um 40 I To report fel S 18 75sq mm Threshold for Terminal Vellus hair diameter um 40 I To report After entering New patient 1 1 Fig 1 information 1 2 and filling out the Outpatient card data 1 3 in order to proceed with the diagnostic session click Phototrichogram module button 1 21 The Phototrichogram diagnostic session window
7. 13 0 Fig 13 will open If the patient has been entered into the program already select the name from Patient s name list 1 15 Fig 1 and proceed to the diagnostic session www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter iS Phototrichogram TTICNOSCI Pro l Ga L richosciencePro module e 13 1 Getting started Image acquirement In the opened Phototrichogram section window 13 1 Fig 13 1 press the Scan icon 13 5 Image capture window will open Place the Diagnosis Scope lens optimally with magnification from x10 to x60 on chosen location of patient s Parietal area Androgen dependent zone and position the mouse cursor within the image capture window if a snapshot button on your Scope cannot be used After good quality image is obtained lock it by pressing the left mouse button Click OK and the picture will appear in the left window designated for Parietal area analysis Perform the same sequence of operations for the image window on the right to study the second normally Occipital area Androgen independent zone of patient s scalp NOTE Images of the scalp and hair can be also loaded from file by pressing appropriate icon 13 4 Any files to be uploaded into the program have to be located in the Additional studies folder created by the program during installation For convenient data management each new patient gets a personal subfolder c
8. If any error occurs during specific action it can be consistently cancelled To do this click Cancel icon 6 14 If you need to cancel any actions within selected area press the Clear field icon 6 11 then press down the left mouse button and draw with cursor an area where you want to cancel all the actions trace the cursor over the information to be removed in the direction from upper left side to lower right and down Release the mouse button All actions within the encircled area will be removed Clear function 6 10 is used to completely remove all previously performed actions e 6 2 Hair diameter measurements and calculations using the second method Click on Manual detection mode icon 6 8 and release Diameter auto measurement mode icon 6 9 to disable this function Place mouse cursor on any selected hair edge click the right mouse button and drag the cursor across the width of hair to its other edge perpendicular to the shaft As cursor has been positioned on opposite edge release the button The figure will appear displaying the performed measurement of the hair diameter in microns Proceed to the next hair diameter measurement 7 NOTE For detailed information on the measurements performed click Information icon 6 13 The absolute number of measured hair total amount of Terminal and Vellus hair mean hair diameters thick medium and thin hair ratio degree of Anisotrihosis data will appear with
9. If working without a mouse wheel use Slider 13 3 located in the upper left corner of each window www TrichoSciencePro com Professional hair and scalp diagnostic software Chapter 13 Phototrichogram oe ichoSciencePro ocala e 13 6 Phototrichogram calculation using fourth method with manual detections This is another method to simultaneously measure in manual mode both hair density and their diameters This method is designated to hair types that may not get detected by any automatic or semiautomatic mode due to being really thin grey or light shaded etc This mode is also being used for corrections for similar hair types with all 3 previous methods above For more accurate hair diameter measurements before processing an image select for proper field of view and increase the scale as described at the beginning of paragraph 13 3 Phototrichogram calculation using first method with automatic detection Press on Manual detection mode 13 15 and depress Diameter auto measurement mode 13 16 buttons if it has been activated for previously used detection mode Position cursor at the end of hair distal end base approximately in the middle of the shaft press and hold down the left mouse button move the cursor along the shaft to the proximal end tip of the hair The length of the line drawn is very important for proper calculation of Anagen to Telogen hairs ratio or rates of hair growth Relea
10. Phototrichogram T j h S l P l Ga lrichosciencePro module NOTE Image window Choose frame icon 13 25 allows to obtain additional images for Phototrichogram calculations in new windows added on top of the previous one These additional calculations in the new windows may significantly increase reliability of the measurements All the results in charts and in report for a given Parietal or Occipital area can be calculated as the average of all measurements To obtain the average values of the measurements across several windows click the Mean arithmetic value icon 13 7 NOTE Any operations performed while working with the program results are stored by default in the final report If you do not want to save results into report uncheck To report checkboxes of associated chart and data table as indicated above Even if you choose not to save information into the report it does not mean that this data is lost after the session ends All data obtained will be stored if the session itself is saved 13 11 Information function e For more detailed information on the measurements performed within the field of view click on the Information icon 13 28 All information identical to listed in chart and data tables for Chart function 13 11 described in paragraph 13 10 Chart function above will be listed on the image which can be printed 13 7 or saved 13 6 as a separate image file
11. Place the mouse cursor on chosen image section and make one or more clicks with the left mouse button The degree of magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to the previous step s The greater magnification is used the higher accuracy achieved especially for hair diameter measurement accuracy In order to move to different magnified image section click on Move icon 13 35 then grab and drag it To return image to original scale click Scaling per window size icon 13 36 e 13 3 Phototrichogram calculation using first method with automatic detection Automatic detection mode quality directly depends on quality of an image being processed Choose for a field of view by Selecting rectangular area 13 32 or Selecting circular area 13 33 in which limits you plan to perform calculations Increase image scale by using Adjust scale 13 34 Place cursor on image and right click once or several times the greater magnification the more accurate measurements of diameters will be achieved Click on Automatic detection mode icon 13 13 Within several seconds Phototrichogram will be processed in automatic mode While processing image in the left diagnostic window three intermediate images will cascade on the right Fig 13 2 Respectively if processing an image www TrichoSciencePro com ichoSciencePro
12. Sex Female in 5 Ibs 105 C Asian Pacific African Caribbean r Teacher Occupation or professional environment Setting the password for access to the information Referral from Physician Complaints Password Hair loss dandruff scalp sensitivity Repeat password CE X Cancel Questionnaire Hair and scalp condition Onset of hair loss 5 months Intensity of hair loss None Moderate or slightly expressed Strongly expressed Duration of hairloss Less than 6 months Over 6 months C Over 6 months with periods of hair improvement and volume restoration Hair thinning C No Yes Frontal parietal area is more affected Diffuse Female Pattern Baldness Ludwig Scale type H Ludwig Scale class 1 C2 C3 Ebling Rook Scale type C1 CU Cm CW CV Ce CB CH CIM CIR Cl C Advanced Frontal Heredity factor in first degree relatives C Yes No Heredity factor in other relatives None Hair type Hair form Hair sort Normal Straight Normal Oily V Wavy V Thin V Mixed Curly Wirly Dry Chem curl Long Extremely dry Chem wave Brittle Damaged Chem straight Split ends Hair length and natural color 16 brown Chapter 3 Trichoscopy module After entering New patient 1 1 primary information 1 2 and filling out the Outpatient card data 1 3 in order to proceed with the diagnostic session click Trichoscopy module button 1 20
13. additional data management every new patient entered into the program gets personal subfolder created under this main folder Folder content can be previewed anytime by clicking Additional studies module button 1 26 Fig 1 e 6 1 Hair diameter measurements and calculations using the first method e Click on Semiautomatic detection mode icon 6 7 Cross with mouse cursor all hairs in a field of view either by one or in groups to count them with their diameters established automatically Only well contrasted hairs will be detected by this mode and not all of their diameters might be measured correctly either Corrections shall be done either by using Cancel 6 14 function to take one or more steps back to correct measurements in error or by Clear field 6 11 function for groups of hairs in one area or Clear 6 10 function to completely remove all previously performed actions Next click Manual detection mode icon 6 8 and press down Diameter auto measurement mode icon 6 9 to activate this function Place the cursor closer to the base of the hair approximately in the middle of the shaft press and hold down the left mouse button move the cursor along the shaft The length of the line drawn is not of an importance it can take up any small area along the hair shaft Release the left mouse button If the hair is still dark enough and well contrasted the line drawn along the hair shaft becomes thicker automa
14. lrichosciencePro module NOTE In case when it is necessary to save the image into a separate file click Save icon 15 13 The image can also be printed out by clicking Print icon 15 14 g NOTE The Information icon 15 6 allows placing any important information within image field by right clicking Add information when prompted Choose fields allows to select what specific information you want to be displayed Reset position is intended to move information into its original location within the image if the image scale was changed or text has moved Select font allows to choose displayed text appearance options NOTE To make it more convenient and accurate when counting hairs in the left image window the size of the window can be increased To do this grab and drag with the mouse the separating border between windows To make the left window larger drag it to the right Movable border 15 18 Respectively when counting hairs in the right window increase the area of the window by moving the border to the left 2 NOTE For more detailed view you can zoom into image to make it larger To do this click on the Adjust scale icon 15 7 Place the mouse cursor on chosen image section and make one or more clicks with the left mouse button Degree of magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to previous step s Th
15. or Sync windows counterclockwise icon 5 2 in the left or in the right window in order to position both images for comparison under the same angle You can now proceed with any calculations required 5 3 Terminal Vellus hair diameter threshold function When hair diameter is being evaluated together with hair density calculations it is also necessary to take into consideration the difference in hairs thickness to automatically sort them into Terminal and Vellus accordingly Generally hairs with a diameter of less than 30 40 um micrometers or microns are considered to be Vellus By default the program auto configures the Threshold setting value for Terminal Vellus hair um 5 10 When calculating the hair density and diameter depending on the mean diameter in the field of view the threshold will be set to one of three values 30 35 or 40um 5 11 This function changes dynamically e g if in the field of view there are mostly thick Terminal hair present the threshold will be automatically set to the value of 40 microns if the hair is mostly fine the threshold will be set to 30 microns if there are various hair present the threshold will be changed to 35 microns In case when you want to set the threshold value on your own you www TrichoSciencePro com will have to turn off the automatic detection To do it right click at the bottom of the window on the Threshold for Terminal Vellus hair um link 5 10
16. 7 Performed Dermatoscopies 1 8 Performed Additional Studies 1 9 and Performed Conclusions and Recommendations 1 10 Depending on what data has to be viewed specific diagnostic session or generated for this session report click on Load session button 1 17 or Show report button 1 18 e 2 1 Patient data management and transfer to another computer To search patients by the date of previous visit use the Search button 1 11 after entering the date of this visit To return back to the list of patients click All sessions button 1 12 Functions Save archive copy of database 1 13 and Restore database from archive 1 14 are needed to save and transfer customer database in cases when TrichoSciencePro software installation or transfer to another PC is required Use the first button to save all data www TrichoSciencePro com Professional hair and scalp diagnostic software ii p te du ction Ke Program TrichoScie ncePro Manager interface Patients module to file After the Software is installed to another PC move the saved database file to this PC and click the second button to restore the patients database for the new program The Patient s Name button 1 15 is used to sort patients in alphabetical order the Date button 1 16 to sort by date To remove unnecessary sessions select the patient s name from the database by left clicking the mouse while holding dow
17. Fig 1 Each standard Trichoscopy 3 0 Fig 3 diagnostic session shall be comprised of Hair density 3 1 Hair diameter 3 2 Scalp analysis 3 3 Hair roots analysis 3 4 Hair shafts analysis 3 5 section steps and Conclusion Print results 3 6 completion 3 1 Getting started Image acquirement Click on the first Hair density button 3 1 and press the Scan icon 3 8 for the right image window The Image capture window 3 10 will open Place the Diagnosis Scope www TrichoSciencePro com ichoSciencePro 2 Professional hair and scalp diagnostic software Chapter 3 Trichoscopy module a lens optimally with magnification from x25 to x60 on chosen location of patient s Parietal area Androgen dependent zone and position the mouse cursor within the Image capture window 3 10 if a snapshot button on your Scope cannot be used After good quality image is obtained lock it by pressing the left mouse button Click OK button 3 11 and the picture will appear in the window on the left designated for Parietal area hair density analysis If locked image is not satisfactory cancel it by pressing corresponding button 3 12 Perform the same sequence of operations for the image window on the right to study the Occipital area Androgen independent zone of patient s scalp e NOTE Images of the scalp and hair can also be loaded from a file by pressing ap
18. Hair shafts analysis Conclusion Print results UcinawwsCOpy Vv K Er 2 Indicate diagnosis gt N z Follicular and Interfolicular F Section title Patterns i a Select image m V To report ae es t J HIRI www TrichoSciencePro com Professional hair and scalp diagnostic software na 8 La 1 roots analysis TrichoSciencePro Click on the third Hair roots analysis button 3 4 Fig 3 and press the Sean icon 8 1 Image capture window will open Place the Diagnosis Scope lens on extracted hair root s and position the mouse cursor within image capture window if a snapshot button on your Scope cannot be used After a good quality image is obtained lock it by pressing the left mouse button Click OK and the picture will appear in the left window From the right window scrollable area representing diagnostic Sample database 8 2 choose the diagnostic image that is most applicable to the current case Place cursor on the selected image and press the left mouse button The selected image will appear in the right window The data will be saved into report by default The report will contain obtained image of the hair roots and the diagnosis name from the heading of the chosen sample image on the right If you do not want to save results into report uncheck To report checkbox 8 3 in the bottom left c
19. Move up Ctrl U Total iron binding capacity TIBC Move down hD Electrolytes and blood Download from file X Cancel Total protein Albumin Globulin Albumin Globulin ratio Calcium Calcium ionized Magnesium Potassium Sodium Glucose fasting mg dl Glucose 2 hours postprandial mg dl Hemoglobin Alc LDH lactate dehydrogenase SGOT AST SGPT ALT Uric acid male Uric acid female Prasting Dhaanhalinsnn Print report Download into MS Word I To report www TrichoSciencePro com ichoSciencePro ca e Professional hair and scalp diagnostic software Chapter 20 Automatic conclusion o a e Chapter 20 Automatic conclusion function In order to proceed click Automatic Conclusion function button 1 29 Fig 1 The Automatic Conclusion window 20 0 will open This function is implemented to calculate for the differential diagnosis between most common Alopecia Androgenetica and Telogen Effluvium hair loss diagnoses Calculations are based on Outpatient card 1 3 Fig 1 questionnaire information and Trichoscopy 1 20 Phototrichogram 1 21 and Trichogram 1 22 sessions calculated data This information as well as other subjective and objective data obtained during diagnostic sessions is being collected and processed in a specialized table which assigns and counts specific points For the conclusion to be correct it is important to have quest
20. NOTE If any additional information has to be entered into modules sections 19 2 19 7 go to the relevant section place mouse cursor anywhere within information listings 19 9 and click the right mouse button From the opened menu 19 10 select the Add prompt to open Add record window 19 11 Enter the new item name and in table s Add section choose where to place it If you want to enter a new section title click the checkbox on the right This will center the new record and make it bald Click OK to save changes You can Delete record or Download from file any text files by selecting appropriate prompts If changes have to be applied to any existing item in the list select it first by left clicking the mouse You can edit information by using Rename Find Move up and Move down prompts Also there is Detailed information prompt which is designated for adding extended information to any listed items By selecting this option the empty MS Word file will open allowing to conveniently enter any important information per user discretion Any information entered will be saved by default and an i icon will appear next to selected item name Thus while viewing informational listings it can be easily understood which items have additional detailed descriptions These descriptions may be deleted anytime by using Delete information prompt e 19 2 Ending session Perfor
21. Professional hair and scalp diagnostic software C 7 Scalp analysis TrichoSciencePro one or more clicks with the left mouse button Degree of magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to previous step s The greater magnification is being used the higher accuracy is going to be achieved In order to move to different magnified image section click on Move icon 7 12 than grab and drag it To return the image to its original scale click Scaling per window size icon 7 13 Also Choose frame icon 7 7 allows to obtain additional image s in the new window s added on top of the previous one Before proceeding to diagnostic session make sure Scope scaling function 7 5 settings have been set according to paragraph 3 3 Scaling settings based on Diagnosis Scope magnification above The proper settings will directly affect the accuracy of Linear length function 7 9 when measurements of any objects of interest are being performed To measure length press and hold down either mouse button then move the cursor to destination and release the button The actual linear measurement value in millimeters will be showing in the top right corner of the image window once the length is set the final result will display by the measurement site 1 z gt Eth Start session 2 20 2015 10 11 05 AM Ar m
22. Report Performed Additional se 2 20 2013 10 45 4 Set template for report Select video capture device Performed Conclusions and Recommendations 2 20 2013 10 50 05 AM ae Save archive copy of database v Restore database from archive gt 7 Enter patient s name Racial variations of hair New patient Outpatient card Sex CM CF European Caucasian Latin Mediterranean Asian Pacific Patient search by session date First date fe Fs Alrican Caribbean Last date a FE oA OK X Cancel Search All sessions E L Fig 1 gir Gir i www TrichoSciencePro com Professional hair and scalp diagnostic software ichoSciencePro it TT Chapter 2 Introduction to Program Manager interface Patients module P y art session 2 22 2015 p lt u E X Outpatient card Journal course of disease prescriptions analysis 5 T E Profile picture il Ej 2 6 2 7 2 8 29 EET X Cance Print V To report Racial variations of hair ee a an ko G Ew c Addional information Height Weight C Latin Mediterranean
23. To report checkbox 15 27 in lower right corners of applicable calculator tables accordingly The generated report will open up behind diagnostic session window as a MS Word document file This convenient format of reporting allows to add edit delete any information within it per user discretion Print the report and close it You will be prompted to save it before exiting When finished exit by closing diagnostic session www TrichoSciencePro com Professional hair and scalp diagnostic software i er 15 Dermatoscopy TrichoSciencePro mode window You will be prompted to save session data If saved your diagnostic session will be recorded and appear in the Performed Dermatoscopies module 1 8 Fig 1 in the form of date and time of the session Any recurring patient sessions will be also recorded and listed in the module if saved To choose the session of interest right click on the appropriate date so it gets highlighted in blue and proceed with clicking on the Load session button 1 17 or the Show report button 1 18 Other functions settings are identical to described in paragraph 14 2 Ending session Generating conclusion Performed Trichograms module a ae a es i orithm for melanoma and other tumor estimation by Argeniziano Algorithm for melanoma and other tumor estimation by Argeniziano Criteria Features Points Mark if applicable Evolution of tumors By color wall t
24. all three To report Phototrichogram Hair density Hair diameter checkboxes 13 29 Fig 13 Even if you choose not to save data into the final report it does not mean that this data is lost after the session ends All data obtained will be stored if the session itself is saved Other report options and directions are identical to those described in Chapter 10 Generating conclusion report function above ATTENTION If after the diagnostic session completion the session s report was generated and saved it will be listed in the Performed Phototrichograms module 1 6 Fig 1 with the sign following the date and time of the session Only in this case the Show report button 1 18 will be enabled www TrichoSciencePro com A Phototri Meam Patient Bob JMainsdil J T Phototrichogram Conclusion Print resuilll Phototrict I Oe dow 1 S 27 00sq mm Time period betweenieasurements hours 48 f Parietal area q Phototrichogram 100 80 Hair density Hair diameter 140 120 BBB Total Anagen hairs 68 26 per 27 00 sq mm Bi Total Telogen hairs 32 12 per 27 00 sq mm BB Terminal among Anagen 65 E Hi Terminal among Telogen 50 BB vettus among Anagen 35 BB veus among Telogen 50 Mean diameter of
25. and the picture will appear in the left window In the the right window scrollable area representing diagnostic Sample database 15 20 choose the diagnostic image that is most applicable to the current case Place cursor on the selected image and press the left mouse button The selected image will appear in the right window 15 19 Linear measurer function 15 2 and or Circular measurer function 15 3 allow to estimate the size area and diameter as well as the symmetry of the skin structures i e lesions neoplasms melanomas tumors etc Both diagnostic sessions of this module have Calculators functions 15 17 with three most common Dermatoscopic algorithms of pigmented lesion assessment You may choose from ABCD ABC and Argeniziano calculator algorithms 15 25 for melanoma and other tumor estimation The ABCD algorithm requires the user to enter points in its third graph Left click on 0 and enter the corresponding number of points For the ABC and Argeniziano algorithms mark corresponding points in the fourth graph if applicable When finished you can evaluate results by pressing Evaluation of results button 15 26 for additional data i NOTE In order to add new diagnostic images to Sample database 15 20 place mouse cursor over the image on the left and right click You will be prompted Add image to Own Base Left click on it in order to open the Sam
26. e 4 5 Perifollicular sign function G Perifollicular sign function 4 5 is designated to mark up and count Exclamation mark hairs Pointed hairs Broken hairs Cadaverized hairs Yellow dots Red dots White dots Click the icon to open up perifollicular sign menu select the corresponding perifollicular sign and mark its location on the image by placing cursor on it and clicking the left mouse button The information on the number of perifollicular signs in one or more fields of view will be provided on chart and saved into report Perifollicular sign presence may be quite critical for proper interpretation of obtained density counts For example the sample image on Fig 4 shows numerous Yellow dots indicating the presence of empty follicles thus the Anagen phase delay which represents quite typical clinical appearance for Alopecia Androgenetica With treatment applied to achieve new hair growth from these follicles there is a possibility eventually to have more hairs and less yellow dots www TrichoSciencePro com icho SciencePro measurements and calculations Follicular unit counts Zz Professional hair and scalp diagnostic software Chapter 4 Hair density and diameter O a e 4 6 Chart function After counting all the hairs in the field of view click the Chart icon 4 16 to open the composite chart and data window The density chart and data 4 26 on the left
27. ease and feel relaxed Very often 8 feel as if am slowed down Sometimes Hospital Anxiety and Depression Scale 3 get a sort of frightened feeling like butterflies in the stomach Occasionally JOU URAC ISSR E TEI Te Ge pLnNGaend 1 I feel tense or wound up Most of the time 2 I still enjoy the things I used to enjoy Definitely as much 11 feel restless as have to be on the move Gute akt 3 I get a sort of frightened feeling as if something awful is about to g ling a Yes but not too badly 12 look forward with enjoyment to things Definitely less than I used to happen Fil get sudden fesinge of patie TEEN 4 I can laugh and see the funny side of things Not quite so much now 5 Worrying thoughts go through my mind A lot of the time 14 can enjoy a good book or radio or TV program Not often 6 L feel cheerful Not often 7 I can sit at ease and feel relaxed Very often 8 I feel as if I am slowed down Sometimes 9 I get a sort of frightened feeling like butterflies in the stomach Occasionally I don t take as much care as I 10 I have lost interest in my appearance should 11 I feel restless as I have to be on the move Quite a lot 12 I look forward with enjoyment to things Definitely less than I used to 13 I get sudden feelings of panic Not very often 14 Ican enjoy a good book or radio or TV program Not often Conclusion Subcl
28. eft zs Professional hair and scalp diagnostic software Chapter 13 f Phototrichogram on the right three intermediate images will cascade on the left The first window will display Original image 13 52 the second Filtered image 13 53 and the third Processed image 13 53 You can close these images using Cancel automatic detection preview 13 24 and reopen using Automatic detection preview 13 23 buttons if needed when correcting obtained measurements After processing all detected and measured hairs get marked up by four different color strips either in green for Terminal in Anagen blue for Terminal in Telogen red for Vellus in Anagen and pink for Vellus in Telogen Since typically automatic detection mode does not allow for completely accurate results as some hairs may not be processed properly an image correction is being performed by next step Any hairs which have been detected partially i e color strip not passing by entire length or width of hair a correction shall be done manually Press on Manual detection mode 13 15 and Diameter auto measurement mode 13 16 buttons Position cursor at the end of color strip over hair so it turns into cross Press down left button of the mouse and continue the line to hair distal or proximal end tip or base Release the button and if hair diameter did not get detected automatically or was detected incorrectly rota
29. follicular unit is a group of adjacent growing hair eTo perform this calculations click Follicular unit count mode icon 13 18 Place the cursor closer to the base of the hair and press the left mouse button as many times as there are hairs in a specific follicular unit mouse button clicks should be performed in quick successions Program allows estimation for single double triple as well as separate follicular units with four and five hairs The chosen number of hairs will be displayed in case of any mistake use Cancel icon 13 37 to return to previous step or click right mouse button to start over The information on follicular unit counts and distribution in one or more fields of view will be saved into report and can be displayed with image Information 13 28 www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter gy Phototrichogram TrichoSci Pro Gaz LrichosciencePro module 13 9 Perifollicular signs function E Perifollicular signs icon 13 19 is designated to mark up and count Exclamation mark hairs Pointed hairs Broken hairs Cadaverized hairs Yellow dots Red dots White dots Click the icon to open up perifollicular sign menu select the corresponding perifollicular sign and mark its location on the image by placing cursor on it and clicking the left mouse button The information on the number of perifollicular signs in
30. hair can be also loaded from file by pressing appropriate icon 7 1 Any files to be uploaded into the program have to be located in the Additional studies folder created by the program during installation For convenient data management each new patient gets a personal subfolder created under the Additional studies folder Folder content can be previewed anytime by clicking the Additional studies module button 1 26 Fig 1 NOTE In case when it is necessary to save the image into a separate file click Save icon 7 3 The image can be also identically printed out by clicking Print icon 7 4 NOTE By means of Point localization icon 7 6 you can mark up specific measurement points on patient s scalp where the hair counts have been performed You can utilize this information for future reference The steps are identical to 4 2 Point localization function description above i NOTE By means of Marker icon 7 8 you can mark up with different color any image sections which may be important to pay attention to during the diagnostic session Select the desired color marker and circle an area or a subject of interest Any mark ups on the image can be deleted by using Clear icon 7 10 s NOTE For more detailed view you can zoom into image to make it larger To do this click on the Adjust scale icon 7 11 Place the mouse cursor on chosen image section and make www TrichoSciencePro com
31. in form of a circle or rectangle square to be analyzed To do this place the cursor in the starting point press and hold down left mouse button move the cursor to the end point and release the button The actual square size S of selected rectangle in sq mm or square size S in sq mm and radius R in mm of selectable circle will be displayed in the top right corner of the image window Once the mouse button is released and the area is set the values S for rectangle or S and R for circle 5 9 will be displayed in the image window bottom left corner which by default is showing the actual www TrichoSciencePro com icho SciencePro density and diameter calculations 2 Professional hair and scalp diagnostic software Chapter 5 Special functions for hair a square size S of original image obtained To cancel the selected area quickly click once the right mouse button For more convenient analysis you can enlarge the image by zooming into it To do this click on the Adjust scale icon 5 6 Place the mouse cursor on the chosen image section and make one or more clicks with the left mouse button Degree of the magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to the previous step s The greater magnification is used the higher accuracy of hair density and diameter measurement is achieved In order to move to a
32. links to Program general overview and this user manuals as well as your Diagnosis Scope setup and instructions For additional support refer to http TrichoSciencePro com e 1 1 Personal computer hardware other software and network requirements PC at least 1 4GHz 1GB of RAM 20GB HDD Full HD screen 3 USB 2 0 ports d Operating system Win 7 8 10 Other software MS Word Acrobat Reader E Internet connection for online registration to complete setup and to access reference materials ATTENTION Before beginning to work with the TrichoSciencePro software connect your Diagnosis Scope e g TrichoScope DermoScope VideoDermoScope MicroCamera etc to your computer and set its drivers Configure scaling according to the selection of your Diagnosis Scope magnifications Proper scale settings should be established for software modules Trichoscopy and Express Trichoscopy primarily for Hair Density and Hair diameter windows also Phototrichogram Trichogram and Dermatoscopy By default Program may be configured to various lower magnification settings for Hair density sections of Trichoscopy and Express Trichoscopy sessions as well as for Phototrichogram Trichogram and Dermatoscopy sessions Same as for default settings for higher magnifications for Hair diameter sections of Trichoscopy and Express Trichoscopy sessions Refer to parag
33. per sq cm J Mean diameter All Terminal hairs gt 30 nm 46 7 2 1 nm BBB Terminat hairs 62 160 per sa cm BB Measured hairs diameter H Vetus hairs 38 96 per sa cm Normal mean diameter for this hair type E Normal mean density for this hair type Measured total 48 hairs per 18 75 sq mm Mean diameter All hairs 36 2 3 pm Follicular units per sa cm 154 7 Measured Terminal hairs gt 30 pm 62 30 per 18 75 sq mm Sinale follicular units 58 6 17 per 18 75 sa mm Measured Vellus hairs lt 30 nm 38 18 per 18 75 sq mm Double follicular units 27 6 8 per 18 75 sa mm 5 s Triple follicular units 13 8 4 per 18 75 sq mm Among Terminal hairs s ni a Thin hairs 30 60 pm 90 Yellow dots total 4 in 1 field of view Regular hairs 60 80 nm 10 Anisottichosis 36 7 M To report em I To report s gt S 18 75sqmm Threshold tor Terminal Velus hair diameter wm 30 F To repo gt 18 75se mm_ Threshold for Terminal Vells hair diameter um 30 F To report CZS Optional functions and settings for hair density and diameter calculations needed when evaluating applied treatment dynamics or conducting any research which requires hairs to be calculated within a set size circle area with its center marked on the scalp with a tattoo etc Click Select rectangular area icon 5 4 Fig 5 or Select circle area icon 5 5 and scroll the mouse cursor to select the size of the area
34. perpendicular to hairs being crossed their diameters will be measured properly while maintaining hair density count When processed all measured hairs get marked up by two different color strips either in red for Vellus or green for Terminal The darker green color shows for more thick in diameter hairs Perform measurements of all hairs in given field of view Only well contrasted hairs will be detected by this mode and not all of their diameters might be measured correctly either Some hairs in the field of view may not get detected properly or at all like very thin or light shaded hairs and hairs which get attached side by side to neighboring hairs In such cases at line crossing hair is not getting any color strip or its width is not corresponding to hair thickness Corrections shall be done either by using Cancel 4 24 function to take one or more steps back to correct measurements in error or by Clear field 4 10 function for groups of hairs in one area or by Clear 4 9 function to completely remove all previously performed actions To complete hair density and diameter measurements proceed with using the second method with manual density detection and diameter auto measurement modes described next in paragraph 4 2 e 4 2 Hair density and diameter measurements and calculations using second method This is another method to simultaneously measure hair density and their diameters mostly used to complete first metho
35. report check uncheck To report checkbox 4 28 located in the bottom right of each chart 4 7 Point localization function Point localization icon 4 18 opens Point localization table 4 29 to mark up specific measurement points on the scalp diagram where the hair counts have been performed Click Localize icon 4 30 place mouse cursor on any standard point marked with a red circle then if necessary move the cursor to the required location and left click the mouse This way the coordinates of a measurement site on the scalp will be recorded If a separate spot mark is wanted click on New point marker icon 4 31 and place a new mark at chosen location then proceed with its localization as above if necessary It is often important to memorize measurement sites used during the session since eventually it may be important to carry out control measurements in same location during patient s recurring visits Right clicking on Information icon 4 32 allows by choosing Add information item from pop up menu to add any additional information or comments to the diagram select its font move text by grabbing it with the mouse reset its position if it was moved and save changes on exit 4 8 Choose frame function Choose frame icon 4 19 allows to obtain additional image s for hair density calculations in the new window s added on top of the previous one s These additional den
36. side are representing measurement summary of the hair density The diameter chart and data 4 27 on the right side are representing measurement summary of hair diameters in case if density calculations were performed using the first method If the second method was used the right side of the chart will stay empty In this case for diameter chart and corresponding data information refer to next Trichoscopy session section Hair diameter 7 00 Fig 7 below The blue bar area on both charts represents the mean density and diameter for specified for the patient racial type of hair On the hair density chart on the left yellow column represents the total amount of hair per sq cm green column the number of Terminal hair red the number of Vellus hairs On the hair diameter chart on the right each measurement taken is represented by a red column If a lot of hair diameter measurements were performed the red curve will be displayed instead of separate columns Single yellow column reflects the mean diameter of Terminal hairs only excluding all Vellus hairs The chart window can be moved across the monitor into any convenient location to allow for easy continuation of hair measurements if necessary In order to move it point to its title bar with the mouse cursor then left click and drag the window In order to increase or decrease any window size in any direction point and drag any of its corners or borders To save delete charts to from
37. software Chapter jis Phototrichogram TTICNOSCI Pro l Qaz LrichosciencePro module NOTE The Syne windows special function 13 29 13 30 may be required for the correct assessment of treatment dynamics when comparing before and after treatment images taken in same area The function and directions including Select circle area 13 33 and Clear background 13 31 are identical to those described in paragraph 5 2 Syne windows above NOTE The Select area special function may be needed to set any rectangular 13 32 or circle 13 33 area of determined size of field of view for more accurate measurements The function and directions including other functions for magnifying 13 34 selected area moving 13 35 to different image parts and restoring 13 36 original scaling for image are identical to those described in paragraph 5 1 Select area above e 13 15 Ending session Generating conclusion Performed Phototrichograms module E After Phototrichogram session is completed determine what data has to be saved to report by using the To report Phototrichogram Hair density Hair diameter checkboxes 13 39 Click on the Conclusion Print the results section 13 2 Generated per above selection report for the diagnostic session will open up behind diagnostic session window as a MS Word document file This convenient format of reporting allows to add edit delete any data within it per user di
38. 21 x Parietal area Norm Total Anagen 63 To 95 0 To 18 To 3 To 4 X Close Absolute amount 4 Occipital area z 27 Total Anagen 33 67 EE Norm To 95 0 To 18 To 3 To 4 e After entering New patient 1 1 Fig 1 information 1 2 and filling out the Outpatient card data 1 3 in order to proceed with the diagnostic session click Dermatoscopy module button 1 23 The Dermatoscopy section window 15 0 Fig 15 will open If the www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter 15 Dermatoscopy TTICNOSCI Pro i Ga lrichosciencePro module patient has been entered into the program already select the name from Patient s name list 1 15 and proceed to the diagnostic session e 15 1 Conducting the Dermatoscopy session Each standard Dermatoscopy 15 0 Fig 15 diagnostic session is composed of General Dermatoscopy and Pigmented Lesions diagnostic sections steps and Conclusion Print results completion step 15 1 Both diagnostic sections are identical in use In the opened section window press the Scan icon 15 12 image capture window will open Place the Diagnosis Scope lens on chosen location of patient s scalp and position the mouse cursor within image capture window After good quality image is obtained lock it by pressing the left mouse button Click OK
39. 30 Fig 1 by selecting To report checkbox 16 6 in the lower right corner of the calculator window www TrichoSciencePro com Zz Professional hair and scalp diagnostic software Chapter 16 Hair calculator module richo SciencePro Trichometry functions e 16 2 Trichometry function growing hair test In order to proceed click Trichometry growing hair test function 16 6 button The Trichometry growing hair test window 16 17 will open This function allows for retrospective calculation of total quantities of hairs shed within 5 4 3 2 consecutive months preceding to the test To carry out the test a fixed quantity of hairs growing within neighboring follicular units from select scalp areas is being epilated and affixed to a scotch tape in order to measure their lengths Enter the Date of hair sampling 16 18 into appropriate field and amount of hairs collected for the test depending on their lengths into the left table column Total amount 16 19 appropriate fields After filling in applicable data you will get in the right table column an automatically calculated results of the Intensity of monthly hair loss 16 20 for the five preceding to the test months You may Print Download to MS Word Close 16 21 or save results into Summary report 1 30 Fig 1 by selecting To report checkbox 16 22 in the lower right corner of the calculator
40. In the pop up dialog box uncheck the checkbox Automatic threshold determination The link text color will change to black Enter the desired threshold value into Threshold for Terminal Vellus hair actual value um window 5 11 If the threshold has to be reset to automatic mode right click on the Threshold for Terminal Vellus hair um link 5 10 in black and in pop up prompt clear the checkbox Automatic threshold determination The link text color will change back to red thus indicating that threshold determination is being automatically configured again The threshold data above corresponds to the mean European Caucasian hair characteristics For other racial variations of hair automatic thresholds will be set according to the selection in Add patient table 1 2 Fig 1 F Al Trichoscopy Patient Mary Smyth Start Sessions2 20 2013 10 fair dens Le Hair diameter Scalp analysis Hair roots analysis Hair shafts amet is Conclusion Print results _ Parietal area hair density wind LT Occipital area hair density window 1 Bate Elo satis A0 K K K X a 4 5 39 39 x x xi x oD 2 c 9 46sq mm R 1 74 mm Threshold for Terminal Vellus hair diameter um 30 N To report S 9 49sq mm R 1 74 mm Threshold for Terminal Vellus hair diameter um 30 NM To report www TrichoSciencePro com Profes
41. RSs Thi keins Wwomston to image Jie i a General Patient Mary Smyth Start session 09 11 2012 22 11 05 Estimated Parietal area hair density window 1 Density om2 Total 256 100 Terminal 160 62 Vellus 96 38 _ Cancel i gt S 18 75sq mm Threshold for Terminal Vellis hair diameter um 30 vw 4 gt 18 75sq mm Threshold for Terminal Vells hair diameter um 30 v www TrichoSciencePro com icho SciencePro Performed Trichoscopies module 2 Professional hair and scalp diagnostic software Chapter 11 Ending diagnostic session ii ass e Chapter 11 Ending diagnostic session Performed Trichoscopies module When finished you can exit by closing diagnostic session window You will be prompted to save session data If you choose to save it patient s diagnostic session will be recorded and will appear in Performed Trichoscopies module 11 1 Fig 11 in the form of date and time of the session Any recurring patient sessions will be also recorded and listed in the module if saved Any of these sessions may be reviewed anytime To choose the session of interest right click on its date once so it is highlighted in blue color Depending on what has to be viewed specific diagnostic session itself or generated session report click on Load session button 11 2 or Show report button 11 3 ATTENTION If after diagnostic session c
42. Scope scaling icon 3 9 and opening the Scope scaling window 3 13 upload 3 19 a picture with a millimeter scale 3 21 or capture an image of a scale bar 3 20 with your Diagnosis Scope camera Scroll the reference scale with the mouse cursor while holding down the left mouse button 3 22 For example you captured the scale length of 1 mm Release the mouse button You will be prompted Specify the actual thickness of the standard Click OK and enter into the box Thickness of prototype mm 3 18 reference value in millimeters in this case 1 mm Click Save button 3 23 The value for Width of the image capture window 3 14 will be calculated automatically same as the corresponding value for Lens magnification 3 15 will be established In case of any error or if measurement verification is desired click Cancel button 3 24 Any record from any window within Program can be removed or corrected by allocating it with the right mouse button and confirming the request for deletion or correction There are three different methods to calculate hair density which differ by detection mode used semiautomatic and manual including simultaneous automatic diameter measurements as well as just manual for quick density counts only And there is also the additional method advancing all three of above by allowing to associate counted hairs with their distribution per follicular units
43. Ter Mean di PETIT Threshold for for Anagen Telogen hair length mm 0 35 jal amona Anagen 58pm meter of Terminal amona Teloaen 50pm Mean diameter of Vellus amona Anaqen 34nm Mean diameter of Vellus amona Telogen 29pm Hair growth rate 350pm 0 35mm per 24 hours To report 4 Threshold for Terminal Vellus hair diameter um 160 sol 120 40 80 2 40l 20 E Total hairs 159 per sq cm B terminal hairs 65 104 per sq cm BBB vius hairs 35 56 per sa cm Normal mean density for this hair type E Mean diameter All Terminal hairs gt 40 pm 56 2 2 pm EBB Measured hairs diameter Normal mean diameter for this hair type Measured total 43 hairs per 27 00 sq mm Mean diameter All hairs 48 2 4 nm Follicular units per sa cm 103 7 Sinale follicular units 57 1 16 per 27 00 sa mm Double follicular units 42 9 12 per 27 00 sq m To report al S 27 00sq mm Time perio F Toreport 7 Phototrichogram 40 Measured Terminal hairs gt 40 nm 65 28 per 27 00 sq mm Measured Vellus hairs lt 40 nm 35 15 per 27 00 sq mm Among Terminal hairs Thin hairs 40 60 pm 64 Regular hairs 60 80 nm 36 Anisotrichosis 48 7 15 1 pm I To report id between measurements hours 48 Hair density 7 Hair diameter Follicular Units Perifolicular Signs a wj AAAA MEX XK www TrichoSciencePro com
44. The displayed information includes total hair counts and ratios of Anagen and Telogen hairs Terminal and Vellus hairs and their intermediate ratios hair and follicular unit density counts different hair type diameter values with thick medium and thin terminal hair ratios and anisotrichosis values etc If several measurement windows were used click on the Mean arithmetic value icon 13 27 to obtain the average of all the measurements performed d NOTE The information on counting results may be edited amount of information provided font changes or additions to the text To make changes place the cursor within text area and right click From the pop up menu select the desired item and make a correction of the text If you want to add your own information click Add information Choose fields allows to select what specific information you want to be displayed Reset position is intended to move information into its original location within the image if the image scale was changed or text has moved Select font allows to choose displayed text appearance options e 13 12 Hair growth rate calculations Calculation of the hair growth rate is performed automatically based on the difference in the length between Anagen and Telogen hairs within a set period of time In the Phototrichogram study all hairs within certain select area get trimmed down to an identical minimal length and when the image is taken after a certain period of
45. This module is intended to record patient s specific diagnostic conclusions results and applicable notes It also offers extended listings of common diagnoses and additional diagnostic tests as well as mostly used topical oral and physical therapy products and practices to choose from e 19 1 Conducting the Conclusions and Recommendations session In the opened Conclusions and Recommendations window 19 0 Fig 19 from the List of diagnoses section 19 2 select an applicable clinical case by marking up appropriate checkbox chosen diagnosis will be displayed in the right field If proper diagnosis is not listed go to the Diagnosis section 19 1 and type it in Also any other important clinical case related additional information may be entered in this field Other sections of Diagnostic tests 19 3 Topical treatment 19 4 Oral therapy 19 5 and Physiotherapy 19 6 allow to select applicable diagnostic and therapeutic activities from appropriate lists of recommendations The Reference materials section 19 7 offers selection of standard hair loss and other classification diagrams as well as other useful data used in Questionnaire section 2 4 Fig 2 of the Outpatient card module 1 3 Fig 1 The Search engine 19 8 allows to easily find various diagnostic and therapeutic activities available in the program by entering applicable keyword into the search field
46. add to summary report 2 9 Click Additional files 2 10 to open patient s www TrichoSciencePro com AON Ga ncePro Manager interface Patients module zs Professional hair and scalp diagnostic software Chapter 2 Introduction to Program oe personal cabinet also accessible from Additional Studies folder on the desktop to manage any additionally imported independent patient s data like blood work etc Patient s sensitive and confidential information may be protected by password in separate MS Word file Click Additional information 2 11 to enter it in pop up window 2 12 then Save 2 13 to open the file If Cancel 2 14 button used additional information file will not be under password protection This module also contains separate Journal Course of disease prescriptions analysis section 2 1 to record any applicable data d NOTE Completion of the Outpatient card module 1 3 Fig 1 is not mandatory and may be partially or completelly disregarded by user When finished entering new patient data you may proceed with diagnostic sessions by pressing Trichoscopy 1 20 Phototrichogram 1 21 Trichogram 1 22 or Dermatoscopy 1 23 buttons and accordingly completing the selected program module Other studies that can be conducted for patient evaluation include semiautomatic Hair calculator 1 24 Hospital Anxiety an
47. ale as described at the beginning of paragraph 13 3 Phototrichogram calculation using first method with automatic detection Press on Manual detection mode 13 15 and Diameter auto measurement mode 13 16 buttons Position cursor at the end of hair distal end base approximately in the middle of the shaft press and hold down the left mouse button move the cursor along the shaft to the proximal end tip of the hair The length of the line drawn is very important for proper calculation of Anagen to Telogen hairs ratio or rates of hair growth Release the left mouse button If the hair is dark enough and well contrasted the line drawn along the hair shaft becomes thicker automatically coinciding with the thickness of hair If the automatic measurement is performed correctly confirm its completion by clicking the left mouse button and proceed to the next hair measurement If the automatic measurement was carried out incorrectly e g the drawn line does not thicken or goes beyond the diameter of the hair continue to measure hair diameter manually To do this release the left mouse button and scroll the mouse wheel If scrolling forward the line drawn along the hair shaft starts to thicken if scrolling backwards the line will become thinner When the thickness of the line becomes equal to the thickness of the hair shaft click the left mouse button to confirm the proper value of hair thickness measurement Proceed to next hair measurement
48. ale icon 18 1 Place the mouse cursor on chosen image section and make one or more clicks with the left mouse button Degree of magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to previous step s In order to move to different magnified image section click on on Move icon 18 2 than grab and drag it To return the image to its original scale click Scaling per window size icon 18 3 Also Choose frame icon 18 8 allows to obtain additional image s in the new window s added on top of the previous one www TrichoSciencePro com Professional hair and scalp diagnostic software i 9 ee tudies module ESON a week Global photographs study e After completing the Additional Studies session check To report checkbox 18 10 to have data saved into Summary report 1 30 Fig 1 Click the Conclusion Print results module 18 0 Generated per session results report will open up behind session window as a MS Word document file This convenient format of reporting allows to add edit delete any information within it per user discretion Print the report and close it You will be prompted to save it before exiting When finished you can exit by closing the diagnostic session window You will be prompted to save session data If you choose to save it your diagnostic session will be recorded and appear in Performed Additio
49. below e 13 4 Phototrichogram calculation using second method with semiautomatic detection E For more accurate hair diameter measurements before processing an image select for proper field of view and increase the scale as described at the beginning of paragraph 13 3 Phototrichogram calculation using first method with automatic detection Click on Semiautomatic detection mode icon 13 14 Cross with mouse cursor all hairs in a field of view either by one or in groups to count them with their diameters and lengths being established automatically To do that position cursor by measured hairs side press down left button of the mouse and cross with a line perpendicular to hair You may extend this line to www TrichoSciencePro com ichoSciencePro eft zs Professional hair and scalp diagnostic software Chapter 13 Phototrichogram cross more neighboring hairs As long as the line remains perpendicular to hairs being crossed their diameters and lengths will be measured properly When processed all measured hairs get marked up by four different color strips either in green for Terminal in Anagen blue for Terminal in Telogen red for Vellus in Anagen and pink for Vellus in Telogen Perform measurements of all hairs in given field of view Some hairs in the field of view may not get detected properly or at all like very thin or light shaded hairs and hairs which get attached side by side to neighboring ha
50. border between windows To make left window larger drag it to the right Movable border 4 20 Fig 4 Respectively when counting hairs in the right window for Occipital area increase the area of this window by moving the border to the left s NOTE For more accurate hair diameter measurements as well as proper various types of hairs and perifollicular signs determination before starting hair count zoom into image to make it larger To do this click on the Adjust scale icon 4 21 Place the mouse cursor on chosen image section and make one or more clicks with the left mouse button Degree of magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to the previous step s The greater magnification is being used the higher accuracy will achieved for hair diameter diversity measurements In order to move to different magnified image section click Move icon 4 22 then grab and drag To return the image to its original scale click Scaling per window size icon 4 23 6 ATTENTION Anisotrichosis or Polymorphism reflects the degree of deviation of measured hair diameters from established average value In initial stages of Alopecia Androgenetica the degree of Anisotrichosis is increasing Later on large number of Vellus hairs and Yellow dots may reduce the severity of Anisotrichosis However by this time it is going to be obvious that two gr
51. box 16 9 in the lower right corner of the calculator window Also there are two additional calculators included representing Trichometry functions based on hair wash test 16 5 and growing hair test 16 6 results as described below e 16 1 Trichometry function hair wash test In order to proceed click Trichometry function hair wash test function 16 5 button The Trichometry function hair wash test window 16 10 will open This function allows for better understanding of ongoing hair loss intensity and form The test can be carried out only if patient s hair are at least 5 cm long and were not washed at least 3 days prior to the test Enter the Date of hair sampling 16 11 and patient s Current mean hair length cm 16 12 into appropriate fields Count shed during hair wash and collected for the test Telogen hairs based on their lengths Enter results into left table column Hair quantity 16 13 appropriate fields After filling in data required you will get automatically calculated results of the percentages of the Telogen hairs depending on their length in the right column Percentage of hair 16 14 For example if the quantity of shed during wash hairs with lengths up to 3 cm is going to be greater than 20 this will indicate the potential progression of Alopecia Androgenetica As finished you may Print Download to MS Word Close 16 5 or save results into Summary report 1
52. d Depression Scale 1 25 and Additional studies 1 26 modules The separate Express Trichoscopy module 1 27 of the program is dedicated for express diagnostic Trichoscopy sessions to be performed when time devoted to each session is limited The Conclusions and Recommendations module 1 28 is intended for entering patient s provisional diagnosis and recommended treatment plan including diagnostic tests general topical and physiotherapy The Automatic conclusion 1 29 module automatically generates a report based on patient data analysis gathered in previous modules The Summary report 1 30 module allows generation of an extended all in one patient report based on user selections The Set template for report function 1 31 allows customization of report print outs per specific requirements The Select video capture device function 1 19 allows selection of used Diagnosis Scope video input to the program when more computer video inputs are present For returning patients with previously saved diagnostic sessions select patient s name from the list in the Patients directory 1 4 and initiate new diagnostic sessions studies etc as indicated above To see results of previous patient visits select the date of the previous visit in one of the performed diagnostic session windows Those are Performed Trichoscopies 1 5 Performed Phototrichograms 1 6 Performed Trichograms 1
53. d measurements or used on its own when assessing hairs that are densely populated thicker curlier growing in bunches etc especially in a darker shades For more accurate hair diameter measurements increase the size of diagnostic window 4 20 and magnify the image by adjusting scale 4 21 as described in paragraph 4 Click on Manual detection mode icon 4 2 and press down Diameter auto measurement mode icon 4 3 to activate this function Place the cursor closer to the base of the hair approximately in the middle of the shaft press and hold down the left mouse button move the cursor along the shaft The length of the line drawn is not of an importance it can take up any small area along the hair shaft Release the left mouse button If the hair is still dark enough and well contrasted the line drawn along the hair shaft becomes thicker automatically coinciding with the thickness of the hair If the automatic measurement is performed correctly confirm the completion of the measurement by clicking the left mouse button and proceed to the next hair measurement If the automatic measurement was carried out incorrectly e g drawn line does not thicken goes beyond the diameter of the hair or vice versa continue to measure hair diameter manually To do this release the left mouse button and scroll the mouse wheel the line drawn along the hair shaft starts to thicken if scrolled backwards the line will become thinner When the
54. d quality image is obtained lock it by pressing the left mouse button Click OK and the picture will appear in the left window From the right window scrollable area representing diagnostic Sample database 7 16 choose the diagnostic image that is most applicable to the current case Place cursor on the selected image and press the left mouse button The selected image will appear in the right window The data will be saved into report by default The report will contain obtained image of the scalp and the diagnosis name from the heading of the chosen sample image on the right If you do not want to save results into the report uncheck To report checkbox 7 14 in the lower left corner of the image window NOTE In order to add new diagnostic images to Sample database 7 16 place mouse cursor over the image on the left and right click You will be prompted Add image to Own Base Release the button The Sample card 7 17 will open Type the name of diagnosis in Indicate diagnosis field 7 18 and click Save 7 20 or Cancel 7 21 The image will appear at the very bottom of the scroll bar You can also upload more images by clicking Select image 7 19 If necessary you can edit images from the Sample database 7 16 To do this place mouse cursor over the image in database and right click From the menu select an option add delete change or move NOTE Images of the scalp and
55. diameter chart and data 6 16 represent measurement summary on hair diameters The blue bar area on the chart represents the average diameter for specified type of hair On the hair diameter chart each measurement shows as a red column If a lot of hair diameter measurements were performed the red curve will be displayed instead of separate columns Single yellow column reflects mean diameter of Terminal hairs only excluding all Vellus hairs The chart window can be moved across the monitor into any convenient location to allow easy continuation of hair measurements if necessary To move it point to its title bar with the mouse pointer then left click and drag the window In order to increase or decrease window size in any direction point and drag any of its corners or borders To save delete charts into from final report check uncheck To report checkbox 6 17 located in the bottom right portion of the chart identically to all session data being saved by checking To report checkbox 6 19 in the bottom of image window If hair density and diameter measurements were performed in several windows for different images by means of Choose frame icon 6 5 the chart will reflect the arithmetic mean value of all the measurements in all the windows added NOTE There are four racial hair variation types that are distinguished based on the differences in their morphological characteristics European Caucasian Latin Mediterranean Asian Pac
56. different magnified image section click on Move icon 5 7 then grab and drag it To return the image to its original scale click Scaling per window size icon 5 8 ATTENTION It is important to remember that anytime the area selection is performed the counting of any variables i e hair density diameter follicular units etc shall be performed only within the chosen site e 5 2 Sync windows function e The Sync windows function may be required for the correct assessment of the performed treatment dynamics when you need to compare two images taken in the same area before and after the treatment The after treatment image may be located asymmetrically in relation to image center to the before treatment image In this case for correct comparison of the results it is necessary to place both images identically so that they are not only symmetrically arranged but also displayed at the same angle Load the before treatment image into the left window and the after treatment image into the right By clicking Select circle area icon 5 5 choose identical size of the area in the form of a circle to be analyzed on both images see Select area function description above For additional accuracy it is preferable for the center of this circle to have a certain mark e g tattoo Next clear the surrounding field of view by clicking Clear background icon 5 3 Click Sync windows clockwise icon 5 1
57. displayed in the yellow window by the measurement object or in the upper right corner of the image when measuring and in the left bottom corner under diagnostic image when finished should any measurements of the objects of interest will be performed e 14 2 Ending session Generating conclusion Performed Trichograms module e After completing the Trichogram diagnostic session check To report checkbox 14 19 Click the Conclusion Print the results module 14 0 Generated per diagnostic session report will open up behind diagnostic session window as a MS Word document file This convenient format of reporting allows to add edit delete any information within it per user discretion Print the report and close it You will be prompted to save it before exiting When finished you can exit by closing the diagnostic session window You will be prompted to save session data If you choose to save it your diagnostic session will be recorded and appear in Performed Trichograms module Fig 1 1 7 in the form of date and time of the session Any recurring patient sessions will be also recorded and listed in the module if saved Any of these sessions may be reviewed anytime To choose the session of interest right click on the appropriate date so it gets highlighted in blue Depending on what has to be viewed specific diagnostic session itself or generated session report click on the Load session button 1 17 or the Show report b
58. e 9 2 choose the diagnostic image that is most applicable to the current case Place cursor on the selected image and press the left mouse button The selected image will appear in the right window The data will be saved into report by default The report will contain obtained image of the hair shafts and the diagnosis name from the heading of the chosen sample image on the right If you do not want to save results into report uncheck To report checkbox 9 3 in the bottom left corner The settings and functions of all other session icons are identical to Scalp analysis diagnostic session Fig 7 and are respectively described in Chapter 7 l aig iant Mary Smyth Start session 2 20 2015 10 11 05 AM el er Scalp analysis Hair roots analysis Hair shafts analysis Conclusion Print results _Dermatoscopy signs DrgMain Chota gt Sample database y Y a Healthy Hair Shafts 4 4 a gt ri Pi wy i OB Semyx x sl Sample card E i Indicate diagnosis I Section title F sy Select image X Cancel alel V To report www TrichoSciencePro com ee f Professional hair and scalp diagnostic software Chapter 10 Generating conclusion E MBulestenialtasles acon e Chapter 10 Generating conclusion 5 Click the Conclusion Print the results 3 6 Fig 3 A cumulative report will be generated containing all diagnostic session perfor
59. e drawn is not of any importance it can take up any minimal area along the hair shaft Release the appropriate mouse button and click it again to confirm the detection If doubtful whether the hair is Terminal or Vellus measure its diameter by scrolling the mouse wheel as described in the second method Also if a hair is really thin and it turns quite difficult to measure its thickness magnify the image by increasing its scale as described above After determining thickness of the hair and its state proceed with hair density count 4 4 Follicular unit counts This method compliments first three methods described above and supplements hair density with or without diameter estimates in addition with hair distribution information in follicular unit calculations follicular unit is a group of adjacent growing hair Perform hair density diameter measurements and calculations using previous methods Then click Follicular unit count mode icon 4 4 Place the cursor closer to the base of the hair and press the left mouse button as many times as there are hairs in a specific follicular unit mouse button clicks should be performed in quick successions Program allows to estimate for single double triple as well as for separate follicular units with four and five hairs The chosen number of hairs will be displayed in case of any mistake use Cancel icon 4 24 to return to previous step or click right mouse button to start over
60. e greater magnification is being used the higher accuracy is going to be achieved In order to move to different magnified image section click on Move icon 15 8 than grab and drag it To return the image to its original scale click Scaling per window size icon 15 9 Also Choose frame icon 15 16 allows to obtain additional image s in the new window s added on top of the previous one b ATTENTION Before proceeding to diagnostic sessions make sure Scope scaling icon 15 15 settings have been set according to the paragraph 3 3 Scaling settings based on Diagnosis Scope magnification above The proper settings will directly affect the Linear measurer function 15 2 or Circular measurer function 15 3 data displayed in the yellow window by the measurement object or in the upper right corner of the image when measuring and in the left bottom corner under diagnostic image when finished should any measurements of the objects of interest will be performed e 15 2 Ending session Generating conclusion Performed Dermatoscopies module After completing the Dermatoscopy session click the Conclusion Print the results section 15 0 The report will contain obtained images of the scalp and lesions as well as diagnosis names from headings of the chosen sample image on the right and chosen calculator data If you do not want to save everything into report uncheck To report checkbox 15 29 and or
61. etal area as compared to the Occipital area There is an increase in the percentage of Telogen hairs in the Parietal area as compared to the Occipital area There is a pronounced condition of the Anisotrichosis and an increased percentage of single follicular units in the Parietal area as compared to the Occipital area Though it should be noted that with appearance of the Yellow Dots indicating the presence of empty follicles the calculation of percentage of Vellus hair becomes impractical as their quantity begins to decline since empty follicles in form of Yellow Dots start to replace thinning hairs 2 NOTE An appearance of the Spiky Hairs indicates the intensity of hair loss but does not reflect progressive hair thinning The progressive thinning of hair is best reflected by the Anisotrichosis value and the proportion of Vellus hairs in Telogen phase www TrichoSciencePro com 2 Professional hair and scalp diagnostic it Chapter 20 Automatic conclusion ESCON ace function _ TricMsSciencePro v1 15E Patient s name Performed Trichoscopies Patient name Date 03 02 2012 20 25 40 Trichoscopy Bob Johnson 04 02 2012 10 31 15 Mary Smyth 04 02 2012 9 26 53 Phototrichogram F Automatic Conclusion Patient Mary Smyth Ce Trichogram Dermatoscopy Patient name Mary Smyth Hair calculator Hospital Anxiety and Depression Scale Criteria for differential diagnosis of female pattern a
62. for Image Nr 1 and the after the treatment image into the right window for Image Nr 2 Images can be also loaded from file by pressing appropriate icon 18 4 Any image files to be loaded into program have to be located in the Additional studies folder that was created on the desktop during installation For convenient additional data management for every new patient entered into program a personal subfolder is created under the Additional studies folder Folder content can be previewed anytime by clicking Additional studies module button 1 26 Fig 1 NOTE In case when it is necessary to save the image into a separate file click Save icon 18 6 Image will be saved into the Additional studies desktop folder The image can also be printed out by clicking the Print icon 18 7 After completing the session check To report checkbox 18 10 to have the obtained data saved into the Summary report 1 30 Fig 1 NOTE To get a closer look on any image part in the left window the size of it may be increased To do this grab and drag with the mouse the separating border between windows To make left window larger drag it to the right Movable border 18 9 Respectively when counting hair in the right window increase the area of the window by moving the border to the left NOTE For more detailed view you can zoom into image to make it larger To do this click on the Adjust sc
63. hickness and cell 2 m Atypical pi t grid 7 typical pigment gri pan Distinguish from dermatoscopic sings of pigment regression in skin lesion Morphological substrate of A shroud or blue white veil a shroud or blue white veil is 2 i represented by foci of acanthosis and hypergranulosis over the clusters of melanocytes in dermis Atypical convoluted linear and 2 Atypical vessels dotted vessels Small criteria Atypical stripes By color shape and location 1 E 15 7 IN Dots granules unevenly distributed By color and size 1 a Blots ink stains Assymetric and atypical by color 1 ia Scar like patches of Dermatoscopic signs of pigment depigmentation and dots often 1 pa regression in skin lesion described as pepper like in pattern Results 15 10 ff al S 1871 91sq mm R 24 41 mm V To report Evaluation of results do da www TrichoSciencePro com 2 Professional hair and scalp diagnostic software Chapter 16 Hair calculator module O a ich O S cie Trice P ro Trichometry functions e Chapter 16 Hair calculator module Trichometry functions In order to proceed click Hair calculator module button 1 24 Fig 1 The Hair calculator window 16 0 Fig 16 will open This module allows to calculate total quantity of scalp hair hair growth and hair loss rates to compare this data to mean numbers based on patient s sex age and racial hair variation
64. hold for Anagen Telogen hair length mm window 13 42 After the threshold value is established all hairs with equal or lesser length will be considered to be Telogen hairs while hairs with a greater length will be considered as Anagen hairs By moving the Slider for Anagen Telogen hair length threshold determination 13 43 the threshold value may be dynamically changed during any stage of the Phototrichogram session as well as prior to starting the session or after finishing it Changing the threshold value will affect the Anagen Telogen hair ratio value calculations By default this value is set to 0 35 mm NOTE The Linear length function 13 21 can be used for any length measurements within any field of view The function and directions are identical to those described in paragraph 4 8 Hair length above 13 14 Terminal Vellus hair diameter threshold function When hair diameter is being evaluated along with hair density calculations it is necessary to take into consideration the difference in hair thickness to automatically sort them into Vellus or Terminal hairs Generally hairs with a diameter of less than 30 40 um micrometers or microns are considered to be Vellus hairs The program provides default auto configuration values for the Threshold for Terminal Vellus hair um window 13 44 When calculating hair density and diameters depending on the average diameter in the field of view the threshold
65. ific and African Caribbean types As it shows on charts the boundaries of mean density and diameter values for each hair will be different depending on specific hair variation type This fact is taken into account automatically when registering and introducing patient s personal data into the program The Mean norm is shown on the density and diameter charts within blue bars as the gap between the two red lines These Mean norm boundaries may be adjusted per specialist s decision To accomplish this grab red lines with the cursor and drag them to desired location To save changes right click with the mouse and confirm save settings request NOTE The threshold data above is corresponding to average European Caucasian hair characteristics The program provides by default the auto configuration for Threshold for Terminal Vellus hair um 6 18 establishment unless modified by user for details see paragraph 5 3 Terminal Vellus hair diameter threshold function above For other racial variations of hair automatic thresholds will be set according to the selection in Add patient table 1 2 Fig 1 NOTE To make it more convenient and accurate when counting hairs in the left image window for Parietal area the size of this window can be increased To do this grab and drag with the mouse the separating Movable border 6 15 between windows To make left window larger drag it to the right Respectively when counting hairs i
66. in image field The information on counting results may be edited amount of information provided font changes or additions to the text To make changes place the cursor within the text area Click the right mouse button From pop up menu select the item of interest and make the correction of the text If you want to add your own information click Add information prompt Select field is intended to correct the amount of on screen information Reset field is intended to move this information into its original location within the image if the image scale was changed or text has moved e NOTE Choose frame icon 6 5 allows to obtain additional image s for hair density calculations in the new window s added on top of the previous one These additional diameter calculations in the additional windows may significantly increase the reliability of measurements performed All the results of hair diameter calculations on charts and in the report for a given Parietal or Occipital area can be calculated as the mean arithmetic value of all measurements To obtain mean arithmetic value of all measurements in several windows added click Mean arithmetic value icon 6 12 www TrichoSciencePro com zs Professional hair and scalp diagnostic it Chapter 6 Hair diameter 33 Tricho SciencePro measurements and calculations 6 3 Chart function After counting all the hairs in the field of view click on Chart icon 6 3 The
67. ing diagnostic session Performed Trichoscopies module 29 e Chapter 12 Express Trichoscopy module 30 e Chapter 13 Phototrichogram module 30 13 1 Getting started Image acquirement 31 d 13 2 Phototrichogram analysis 31 13 3 Phototrichogram calculation using first method with automatic detection 32 13 4 Phototrichogram calculation using second method with semiautomatic detection 33 13 5 Phototrichogram calculation using third method with manual detection and diameter auto measurement mode 34 13 6 Phototrichogram calculation using forth method with manual detection 35 13 7 Density correction function 35 13 8 Follicular unit counts 35 13 9 Perifollicular sign function 36 13 10 Chart function 36 13 11 Information function 37 13 12 Hair growth rate calculations 37 13 13 Anagen Telogen hair diameter threshold function 38 13 14 Terminal Vellus hair diameter threshold function 38 13 15 Ending session Generating conclusion Performed Phototrichograms module 39 e Chapter 14 Trichogram module 4 a 14 1 Conducting the Trichogram session 41 e 14 2 Ending session Generating conclusion Performed Trichograms module 42 e Chapter 15 Dermatoscopy module 43 15 1 Conducting the Dermatoscopy session 44 e 15 2 Ending session Generating conclusion Performed Dermatoscopies module 45 e Chapter 16 Hai
68. inical depression Clinical anxiety Print report Download into MS Won Close M To report www TrichoSciencePro com ez Professional hair and scalp diagnostic software Chapter 18 Additional studies module oe icho SciencePro Global photographs study e Chapter 18 Additional studies module Global photographs study After entering New patient 1 1 Fig 1 information 1 2 and filling out the Outpatient card data 1 3 in order to proceed with the diagnostic session click Additional Studies module button 1 26 The Additional Studies section window 18 0 Fig 18 will open This module is intended to be used primarily for Global photographs study assessment to evaluate performed treatment results and or progress however any other images taken by Diagnosis Scope i e Trichoscope or any other microscopic or regular camera e g any specific scalp area changes etc may be uploaded and used per user discretion If the patient has been entered into the program already select the name from Patient s name list 1 15 and proceed to the diagnostic session e 18 1 Conducting the Additional Study session e In the opened Additional studies section window 18 0 Fig 18 press the Scan icon 18 5 the image capture window will open To perform before and after treatment comparison load the before the treatment image into the left window
69. ionnaire information completely filled out as well as various conducted measurement and calculation results i e hair density diameter follicular unit and perifollicular sign counts Terminal Vellus and Anagen Telogen hair ratio assessment data in various scalp locations percentages of Vellus to Telogen hair numbers etc The total results obtained in this table indicate the potential activity of each of these processes Since signs of Androgenetic and Diffuse Alopecia often coexist this issue typically turns to be a frequent cause of diagnostic difficulties You may Print Download to MS Word Close 20 1 or save results into Summary report 1 30 Fig l by selecting To report checkbox 20 2 in the lower right corner of the window NOTE One of the most frequent diagnostic difficulties is to distinguish Female Pattern Hair Loss signs from Chronic Telogen Effluvium in women in the early stages of hair loss development In the early stages of Androgenetic Alopecia despite the reduction in hair density in the Parietal area the total quantity of hairs within the Parietal area remains higher than in the Occipital area The average diameter of hairs in the Parietal area is also reduced but there are no significant changes in diameters of the hairs in the Occipital area There is an increase in the quantity of fine hairs in the Parietal area as compared to the Occipital area and there is a reduction in the quantity of thick hairs in the Pari
70. ions using the first method described in paragraph 4 1 Hair density and diameter calculations using the first method The main difference is based on the approach of how the hairs are being actually marked up for evaluation In case of hair density and diameter calculations it is necessary to mark up only some part of hair shaft no matter how long it may be while for Phototrichogram study it is very important to carefully trace the entire length of each hair Proper hair length determination is critical for calculations of such parameters as the ratio of Anagen to Telogen hairs or rates of hair growth That s why for proper and correct www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter Ia Phototrichogram T j h S l P l Ga lrichosciencePro module Phototrichogram assessment we have to evaluate only hairs which are clearly visible in given field of view Thus any hairs extending beyond the field of view are not being included for Phototrichogram evaluation as their lengths are unclear Although these hairs are examined for proper density assessment see paragraph 13 7 Density correction function below Also another difference with described in paragraph 4 1 Hair density and diameter calculations using the first method is that with the Phototrichogram module there is additional important fully automatic detection mode available for hairs assessment while all other functions are being identical t
71. ir length Total amount intensity of monthly hair loss Total actual quantity of Vellus hair 43548 4400 Over 5 cm long hair Mean hair growth rate mm 24hrs population norms 0 3 0 4 Actual hair growth rate in Parietal area mm 24hrs 0 28 45 em Actual hair growth rate in Occipital area mm 24hrs 0 32 a N Total mean daily rate of hair loss 116 Total actual quantity of hair shed per 24hrs 280 2 3 om Total actual quantity of Terminal hair shed per 24hrs 180 Total actual quantity of Vellus hair shed per 24hrs 1 2 cm Total Download into MS Word Print report Download into MS Word IZ Toreport Fig 16 16 21 16 22 www TrichoSciencePro com e Professional hair and scalp diagnostic software Chapter 17 Hospital anxiety and ichoSciencePro depression scale module e Chapter 17 Hospital anxiety and depression scale module In order to proceed click Hospital anxiety and depression scale module button 1 22 Fig 1 The Hospital anxiety and depression scale window 17 0 Fig 17 will open This module is based on Zigmond A Snaith R 1983 questionnaire The patient should answer 14 questions of this questionnaire by selecting one out of four answer choices After finished click OK to save data or Cancel to exit 17 1 To get evaluation of results press the Conclusion button 17 2 The Conclusion table 17 3 with automatic eval
72. irs In such cases at line crossing hair is not getting any color strip or its width is not corresponding to hair thickness For each case correction including just an adjustment of improperly detected hairs or their completely new assessment as well as for missed at all during detection hairs and all hair density count corrections use same steps and precautions as described in paragraph 13 3 Phototrichogram calculation using first method with automatic detection above ATTENTION Both automatic and semiautomatic detection modes for Phototrichogram calculations may work incorrectly with really dense or intercrossing in between hairs there are high contrasted inclusions within a field of view or hairs are light or too poorly contrasted against scalp poor sharpness of a diagnostic image low resolution of the Scope etc e 13 5 Phototrichogram calculation using third method with manual detection and diameter auto measurement mode This is another method to simultaneously measure hair density and their diameters used to correct and complete first two methods measurements or used widely on its own when assessing hairs that are densely populated thicker curlier growing in bunches etc especially in a darker shades or when wanted to perform a study straight forward without going back to perform corrections For more accurate hair diameter measurements before processing an image select for proper field of view and increase the sc
73. lue bar area represents the mean density for specified for the patient racial type of hair Same data with percentages for these different hair types in addition and follicular unit with perifollicular sign counts is listed below the chart In Hair diameter section each measurement taken is represented on the chart by red column If a lot of hair diameter measurements were performed the red curve will be displayed instead of separate columns Single yellow column reflects the mean diameter of Terminal hairs only excluding all Vellus hairs Same data with percentages for these different hair types in addition and Terminal hairs separation into thin regular and thick groups based on diameters including Anisotrichosis value see paragraph 4 Hair density and diameter measurements and calculations Follicular unit counts below The composite chart and data window can be moved across the monitor into any convenient location to allow easy continuation of hair measurements if necessary To move it point to its title bar with the mouse cursor then left click and drag the window In order to increase or decrease window size in any direction point and drag any of its corners or borders To save or delete charts in final report check uncheck To report checkboxes 13 49 13 50 13 51 located in the bottom right portion of associated chart and data table www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter Ia
74. med Conclusions and Recommendations module E After completing all appropriate sections you may Print Download to MS Word Close 19 12 or save results into Summary report 1 30 Fig 1 by selecting To report www TrichoSciencePro com icho SciencePro Recommendations module 2 Professional hair and scalp diagnostic software Chapter 19 Conclusions and checkbox 19 13 in the lower right corner of the window Click the Download into MS Word button Generated per session results report will open up behind session window as a MS Word document file This convenient format of reporting allows to add edit delete any information within it per user discretion Print the report and close it You will be prompted to save it before exiting When finished you can exit by closing the diagnostic session window You will be prompted to save session data If you choose to save it your diagnostic session will be recorded and appear in Performed Conclusions and Recommendations module 1 10 Fig 1 in the form of date and time of the session Any recurring patient sessions will be also recorded and listed in the module if saved Any of these sessions may be reviewed anytime To choose the session of interest right click on the appropriate date so it gets highlighted in blue and proceed with clicking on the Load session button 1 17 or the Show report button 1 18 Other functions settings are identical to described in pa
75. med studies and results and will open up behind diagnostic session window as a MS Word document file This convenient format of reporting allows to add edit delete any information within it per user discretion Print the report and close it You will be prompted to save it before exiting If some specific data was not included into the report or you wish to include some additional information close the report without saving it Make any changes and open the report again In this case you will be prompted to go to the previously saved report or generate the new one i NOTE If during hair density or diameter diagnostic sessions any additional information was added to images by means of Information icons 4 12 or 6 13 and Mean arithmetic value icons 4 11 or 6 12 when opening report you will be prompted to verify data in Information to image table 10 1 first Select the applicable data in order to proceed Same procedure is applicable if any of these type image shall be printed out or saved F a _ lease DI A Trichoscopy Patient Mary Smyth Start session 2 20 2013 10 11 05 AM o X Hair density Hair diameter Scalp analysis Hair roots analysis Hair shafts analysis Conclusion Print results Parietal area hair density window 1 Occipital area hair density window 1 Gates 1 0 aie igi ole CARAN aE Te 7 ft ermifal h ees SA a a at SAY Anis 1 1 y
76. n Ctrl key you can select names in random order if holding down Shift key you can select names in subsequent order When finished place the cursor within highlighted name s and press the right mouse button From the resulting query select Delete Rename and Find patient in the list as well as New Patient Outpatient card Additional Information or Save patient list to MS Word prompts 1 32 Another important Save to file function 1 33 allows to save into separate file any patient s diagnostic session s in order to move data to another computer accordingly use Download from file function 1 34 to upload data into program from any file previously saved this way G BT M TrichoSciencePro v1 3SE Special Eme lo i fe Patient s name Date Performed Trichoscopiess 5 Trichoscopy Bob Johnson 2 21 2013 4 24 50 PM 2 20 2013 10 11 0 I 2222420132 10 21 15 AM j Delete Del Phototrichogram Rename Trichogram Find CEP New patient Ins Performed Phototrichograr Dermatoscopy 2 22 2013 10 21 1 A Outpatient card F4 feei Hair Calculator Additional information F5 Hospital Anxiety and Depression Scale Save patient list to MS Word C_F Additional Studies Save to file Performed Trichograms Download from file 2 20 2013 10 31 2 l 5 J CEA Express Trichoscopy Performed E 13 i dR aie ti ATAIEKIE onclusions and Recommendations Automatic Conclusion Summary
77. n the right image window for Occipital area increase the area of this window by moving the border to the left NOTE The settings and functions of all other not described icons are absolutely identical to the Hair density diagnostic session Fig 4 and Fig 5 and are respectively described in Chapter 4 and Chapter 5 above www TrichoSciencePro com Professional hair and scalp diagnostic software 6 Hair diameter aie richo S cie nce P ro measurements and calculations Pay attention to the average diameter of thick medium and fine hair percent of Vellus hair and their ratio in the Parietal and Occipital areas Vellus hair amount normally should not exceed 15 20 If this numbers are exceeded it is an indication of the presence of a pathological hair thinning With Yellow spots present Vellus hair percentage starts to decrease since in such cases many hairs have really small diameter and are poorly visualized or do not grow at all Under normal conditions the thick hairs percentage is higher and respectively the thin hairs percentage is smaller in Parietal area in comparison to Occipital area With the development of Androgen dependent Alopecia this proportion starts to change gradually Any record from any window within this computer program can be removed or corrected by allocating it with the right mouse button and confirming the request for deletion or correction l Trichoscopy Patient Mary Smyth
78. nal Studies module 1 9 Fig 1 in the form of date and time of the session Any recurring patient sessions will be also recorded and listed in the module if saved Any of these sessions may be reviewed anytime To choose the session of interest right click on the appropriate date so it gets highlighted in blue Depending on what has to be viewed specific diagnostic session itself or generated session report click on the Load session button 1 17 or the Show report button 1 18 respectively Other functions settings are identical to described in paragraph 14 2 Ending session Generating conclusion Performed Trichograms module G ot 1 I Additional fftuaf Aee Mary Smyth Start session 2 20 2015 10 45 45 AM mA q q Raditonal Studs Conetfion Print results Image Nr 1 taken 2 20 13 10 39 00 AM T Image Nr 2 taken 6 29 13 11 51 11 AM n ase amp 18 8 M To report e V To report www TrichoSciencePro com zs f ie aie hair wie scalp diagnostic one Chapter 19 Conclusions and i Balelsleniels sles ane Recommendations module _ e e Chapter 19 Conclusions and Recommendations module d After completing all diagnostic sessions in order to proceed click on Conclusions and Recommendations module button 1 28 Fig l to open the Conclusions and Recommendations window 19 0 Fig 19
79. nction 10 3 3 Scaling settings based on Diagnosis Scope magnification 10 e Chapter 4 Hair density and diameter measurements and calculations Follicular unit counts 11 4 1 Hair density and diameter measurements and calculations using first method 12 4 2 Hair density and diameter measurements and calculations using second method 13 4 3 Hair density measurements and calculations using third method 14 E 4 4 Follicular unit counts 14 4 5 Perifollicular sign function 15 e 4 6 Chart function 14 4 7 Point localization function 15 4 8 Choose frame function 15 4 9 Hair length function 16 4 10 Marker function 16 4 11 Information function 16 e Chapter 5 Special functions for hair density and diameter calculations 17 5 1 Select area function 17 e 5 2 Sync windows function 18 5 3 Terminal Vellus hair diameter threshold function 18 e Chapter 6 Hair diameter measurements and calculations 20 6 1 Hair diameter measurements and calculations using first method 20 6 2 Hair diameter measurements and calculations using second method 21 E 6 3 Chart function 22 e Chapter 7 Scalp analysis 24 e Chapter 8 Hair roots analysis 26 e Chapter 9 Hair shafts analysis 27 www TrichoSciencePro com ichoSciencePro 2 Professional hair and scalp diagnostic software Table of Contents e Chapter 10 Generating conclusion 28 e Chapter 11 End
80. nd diffuse telogen hair loss in women Additional studies Criteria Female pattern alopecia Telogen Diffuse Alopecia Clinical history Express Trichoscopy Hair and scalp condition Intensity of hair loss Moderate or slightly expressed Conclusions and Recommendations Duration of hairloss Over 6 months Automatic Conclusion Hair thinning Frontal parietal area is more affected Summary report Female Pattern Baldness Ludwig Scale type I 2 Set template for report Heredity factor in first degree relatives Scalp condition Combination Seborrheic dermatitis Areas of redness Performed Conclusions and Recommendations Data of Trichologic objective study Trichoscopy Temna harconi nal tharra Less than 250 for sq cm Over 250 for sq cm Trichoscopy Average Terminal hair diameter without In parietal area is less than in occipital Vellus hair accounted Th parietal area is more than in occipital Trichoscopy 20 y Percent of Vellus hair in parietal area More than 20 Less than 20 l Trichoscopy Ouar Io R Less than 12 for parietal Anisotrichosis in parietal area area Trichoscopy Presence of thin medium and thick hair Presence of all types in parietal area Presence of 2 types out of 3 Trichoscopy Yellow dots Yellow dots applicable No yellow dots Pointed hair Presence of all types Pointed hair possible in parietal area Download into MS Word Close IV To report e Chapter 21 Summary report
81. o measurement tools of Hair density section of Trichoscopy module Fig 4 Therefore based on primary detection mode used there are four different methods for Phototrichogram calculation with automatic semiautomatic manual detection modes and manual detection mode with automatic hair diameter measurements j NOTE To make it more convenient and accurate when processing images the size of the window may be increased To do this grab and drag with the mouse the separating border Movable wall 13 12 between windows To make left window larger drag it to the right Respectively when assessing hairs in the right image window increase the area of the window by moving the separating border between windows to the left NOTE It is important to run Phototrichogram evaluation on a set area within a field of view which may be reduced or limited for greater accuracy or convenience To do that use the Select rectangular area 13 32 or Select circle area icons 13 33 to form rectangular square or circular areas to be analyzed their sizes will be displayed in the lower left corner 13 38 The function and directions are identical to described in paragraph 5 1 Select area function above NOTE For more accurate hair diameter measurements as well as various types of hairs and perifollicular signs determination before starting assessment zoom into image to make it larger To do this click on the Adjust scale icon 13 34
82. ompletion the report per this session results was generated and saved it will appear in the Performed Trichoscopies module 11 1 in form of sign after the date and time of the session Only in this case Show report button 11 3 will be enabled a rr i TrichoSciencePro v13SE Special Edition v7 w wh Fels ee a eee EEE Patient s name Date Performed Trichoscopies j Trichoscopy Bob Johnson 2 21 2013 4 24 50 PM 2 19 2013 3 23 59 PM Mary Smyth 2 22 2013 10 21 15 AM Phototrichogram Show report Trichogram Crj Load session Performed Phototrichogr 2 21 2013 4 24 50 PM Dermatoscopy Hair Calculator Hospital nxiety and Depression Scale Additional Studies Performed Trichograms 2 19 2013 6 44 16 PM Express Trichoscopy Performed Dermatoscopies ae ma 7s conclusions and Recommendations 2 19 2013 4 41 58 PM Automatic Conclusion Summary Report Performed Additional Studies 2 19 2013 6 46 25 PM Set template for report Select video capture device New patient Outpatient card Patient search by session date Performed Conclusions and Recommendations i i Frs daa 2 19 2013 6 47 06 PM Last date i Save archive copy of database Search All sessions Restore database from archive www TrichoSciencePro com Professional hair and scalp diagnostic software TrichoSciencePro
83. on when prompted Choose fields allows to select what specific information you want to be displayed Reset position is intended to move information into its original location within the image if the image scale was changed or text has moved Select font allows to choose displayed text appearance options NOTE For more detailed view you can zoom into image to make it larger To do this click on the Adjust scale icon 14 7 Place the mouse cursor on chosen image section and make one or more clicks with the left mouse button Degree of magnification for selected field of view depends on the number of mouse clicks If it becomes too high click right mouse button to return to previous step s The greater magnification is being used the higher accuracy is going to be achieved In order to move to different magnified image section click on Move icon 14 8 than grab and drag it To return the image to its original scale click Scaling per window size icon 14 9 Also Choose frame icon 14 16 allows to obtain additional image s in the new window s added on top of the previous one ATTENTION Before proceeding to diagnostic session make sure Scope scaling icon 14 15 settings have been set according to the paragraph 3 3 Scaling settings based on Diagnosis Scope magnification above The proper settings will directly affect the Linear measurer function 14 2 or Circular measurer function 14 3 data
84. one or more fields of view will be present on the chart and saved into report It will be also displayed with image Information 13 28 For more information see paragraph 4 5 above 13 10 Chart function After measuring all the hairs in the field of view click on the Chart icon 13 8 to open composite chart and data window containing measurements summary for Phototrichogram 13 46 on the left for Density 13 47 in the middle and for Diameters 13 49 on the right side for either the left image window for Parietal area or the right image window for Occipital area If measurements were performed in several fields of view see description of Choose frame 13 11 function below the charts and data will be reflecting accordingly the average value of all associated measurements In Phototrichogram section the dark brown column on the chart reflects percentage and total number of Anagen hairs the light brown is for Telogen hairs the green is for Terminal among Anagen hairs the blue is for Terminal among Telogen hairs the red is for Vellus among Anagen hairs the purple represents Vellus among Telogen hairs All this data with mean diameters for these different hair types in addition and calculated hair growth rate is listed below the chart In Density section the yellow column on the chart represents the total amount of hair per sq cm green column the number of Terminal hairs red the number of Vellus hairs The b
85. orner The settings and functions of all other session icons are identical to Scalp analysis diagnostic session Fig 7 and are respectively described in Chapter 7 r D A Lichoscopy Patient Mary Smyth Start session 2 20 2015 10 11 05 AM aro mem Ha Per Scalp analysis Hair roots analysis i Hair shafts analysis Conclusion Print results J J _ Hair root image L _ Dermatoscopy signs Tel lair sh e e AE aa a s s Sample database c Ei amp A x h J Anagen Hair gt gt oa e 7 kai he y xj B i gt F re ey 4 ae F gt Section title i T ERNA 3 d s A gt ot ae lt T m y Sample card q tan s I Indicate diagnosis J ay Select image F Save X Cancel HR V To report www TrichoSciencePro com Professional hair and scalp diagnostic software TrichoSciencePro Click on the third Hair shafts analysis button 3 5 Fig 3 and press the Scan icon 9 1 Image capture window will open Place the Diagnosis Scope lens on extracted growing hair shafts and position the mouse cursor within image capture window if a snapshot button on your Scope cannot be used After a good quality image is obtained lock it by pressing the left mouse button Click OK and the picture will appear in the left window From the right window scrollable area representing diagnostic Sample databas
86. oups of hairs thicker and thinning will be present The presence of some minimal values of Anisotrichosis is typical for either patients without a progressive hair thinning or on the contrary in the final stages of Alopecia Androgenetica e 4 1 Hair density and diameter measurements and calculations using first method This is the most convenient and recommended way to simultaneously measure hair density and their diameters Also it is primarily useful in cases when Diagnosis Scope camera used for studies does not have higher magnification capabilities for more precise hair diameter measurements or if there is no greater need to cross verify these measurements For more accurate hair diameter measurements increase the size of diagnostic window 4 20 and magnify the image by adjusting scale 4 21 as described right above Click on www TrichoSciencePro com icho SciencePro measurements and calculations Follicular unit counts zs Professional hair and scalp diagnostic software Chapter 4 Hair density and diameter O a Semiautomatic detection mode icon 4 1 Cross with mouse cursor all hairs in a field of view either by one or in groups to count them with their diameters established automatically To do that position cursor by measured hairs side press down left button of the mouse and cross with a line perpendicular to hair You may extend this line to cross more neighboring hairs As long as the line remains
87. p diagnostic software TrichoSciencePro TRILOGIC LLC is an official developer and distributor of the TrichoSciencePro computer program With any program inquiries purchase and delivery requests applicable technical support and others us or our authorized representatives as follows Russia and CIS countries Company Trilogic Address Krzhizhanovskogo Street 24 35 building 4 Moscow Russia Tel 74955100172 E mail office yourhair ru European Union Company B amp B International Enteprises Address Paneriu Street 45 401 Vilnius LT 03202 Lithuania EU Tel 37060009011 E mail office yourhair eu North America Company B amp B Intemational Enteprises Address 7 Munroe Street Ste 2 Boston MA 02460 US Tel 16178066955 E mail office yourhair us TRI GIC ENTERPRISES www TrichoSciencePro com
88. ple card 15 21 Type the name of the diagnosis in the Sample title field 15 22 and click Save 15 24 The image will appear at the very bottom of the scrollable area You can also upload more images by clicking the Select image button 15 23 If necessary images from the Sample database 15 20 may be edited To do this place mouse cursor over any image in it and right click From the menu select an option to open add delete change or move the selected image NOTE Diagnostic images can be also downloaded from file by pressing appropriate icon 15 11 Any files to be uploaded into the program have to be located in the Additional studies folder created by the program during installation on the desktop For convenient data management each new patient gets a personal subfolder created under the Additional studies folder Folder content can be previewed anytime by clicking the Additional studies module button 1 26 Fig 1 s NOTE By means of Marker icon 15 4 you can choose and mark up with different colors any image sections which may be important to pay patient s attention to during the diagnostic session Select the desired color marker and circle an area or a subject of interest Any mark ups on the image can be deleted by using Clear icon 15 5 www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter 15 Dermatoscopy TTICNOSCI Pro i Ga
89. propriate icon 3 7 Any files to be uploaded into the program have to be located in the Additional studies folder created by the Program on the desktop during installation For convenient data management each new patient gets a personal subfolder created under the Additional studies folder Folder content can be previewed anytime by clicking the Additional studies module button 1 26 Fig 1 e 3 2 Select video capture device function If your computer is equipped with a built in web camera you may still be receiving its image in the capture window when clicking the Scan icon 3 8 instead of an image from the connected to computer Diagnosis Scope Therefore you have to disable webcam driver To do that click on Select video capture device button 1 19 Fig 1 You will be prompted to select applicable Diagnosis Scope input There is also another standard way to disable webcam Go to Control Panel select Device Manager then Imaging Device right click on the webcam icon and select the disable option e 3 3 Scaling settings based on Diagnosis Scope magnification Since TrichoSciencePro software allows to receive and process data in absolute units e g number of hairs per sq cm hair diameter in microns etc while optical equipment used may have different magnification levels setting a proper image acquisition scaling may be necessary before conducting any diagnostic sessions This setting must be p
90. r calculator module Trichometry functions 47 16 1 Trichometry function hair wash test 47 a 16 2 Trichometry function growing hair test 48 e Chapter 17 Hospital anxiety and depression scale module 49 e Chapter 18 Additional studies module Global photograph study 50 e 18 1 Conducting the Additional Studies session 50 18 2 Ending session Generating conclusion Performed Additional Studies module 51 e Chapter 19 Conclusions and Recommendations module 52 www TrichoSciencePro com 2 AN ain hair on scalp diagnostic one Table of Contents TrichoSciencePro 19 1 Conducting the Conclusions and Recommendations session 19 2 Ending session Performed Conclusions and Recommendations module e Chapter 20 Automatic conclusion function e Chapter 21 Summary report function e 21 1 Set template for report function www TrichoSciencePro com 32 32 54 a 56 ez Professional hair and scalp diagnostic software Chapter 1 TrichoSciencePro a icho SciencePro software installation e Chapter 1 TrichoSciencePro software installation Depending on purchased version TrichoSciencePro software supply differs and is specified in attached Installation Manager utility tool Refer to it for your Program version installation and online registration instructions for step by step guidance through the entire process It also
91. raads asion 2 20 2015 10 11 05 AM bo pe B aida E d J E results 4 go roa mean hair thickness wi tow 1 T Occipital area mean hair thickness window 1 visi FLS 88 A Gon O i Cd CMT BEA olo N Sa SS WS a Ly ma l Hair diameter chart Parietal area x E Mean diameter All Terminal hairs gt 30 pm 47 7 2 2 pm E Measured hairs diameter Normal mean diameter for this hair type Measured total 28 hairs per 1 50 sq mm Mean diameter All hairs 44 7 2 3 nm Measured Terminal hairs gt 30 nm 86 24 per 1 50 sq mm Measured Yellus hairs lt 30 pm 14 4 per 1 50 sq mm Among Terminal hairs Thin hairs 30 60 pm 88 Regular hairs 60 80 pm 12 Anisotrichosis 44 7 11 8 pm alel S 1 50sq mm Threshold for Terminal Vellus hair diameter um 30 IV To repor gt S 1 50sq mm_ Threshold for Terminal Vellus hair diameter um 30 V To report www TrichoSciencePro com a hair wis scalp diagnostic one Chapter 7A Scalp analysis JTrichoSciencePro e Chapter 7 Scalp analysis e Click on the third Scalp analysis button 3 3 Fig 3 and press the Scan icon 7 2 Image capture window will open Place the Diagnosis Scope lens on chosen location of patient s scalp and position the mouse cursor within image capture window if a snapshot button on your Scope cannot be used After a goo
92. ragraph 14 2 Ending session Generating conclusion Performed Trichograms module 19 2 19 3 19 4 19 6 19 7 Conclusic s and Recommende ons Patient Mary Sr yth Start session 4 2012 9 26 53 AP DHK a Diagnosis Litt of diagnose Topical treatment Oral tperapy Physiotherapy Reference materials Hair growth assessment Selected Videodermoscopy Photatrichogram Global Photographs Complete Blood Count CBC Serum Ferritin Serum Iron Iron Saturation Transferrin Vv Videodermoscopy Dermatoscopy Classic Trichogram Phototrichogram Conventional and contrast enhanced Phototrichogram Unit Area Trichogram ee on binding capacity TIBC otal protein Hair pul test Alburin Daily hair counts ae Hair Densitometry Glucose fasting mg d Standardized wash test Hair Weighing cat icevorve amin D 25 0H 0 60 second hair count 19 9 Bilirubin Direct Global Photographs s Triglycerides a a Total Serum Cholesterol Hair Feathering test HDL Cholesterol Hair Weighing On Mechanical test of hair quality Optical light and polarizing microscopy Confocal laser scanning microscopy Add Ins Add Iron status blood Delete record Del To the beginning Download image Rename Complete Blood Count CBC E it a Compl i CBC eed eae To current position Serum Feritin Pyrenean Serum Iron Detailed information kons Delete information piion Saturation JT Section title W Transferrin
93. raph 3 3 Scaling settings based on Diagnosis Scope magnification for settings verification and additional setup information e Chapter 2 Introduction to Program Manager interface Patients module After TrichoSciencePro software is installed and registered open the program by double clicking on the icon generated on your computer desktop This action will take you to Program Manager Fig 1 which is the main interface for all Software functions To start with a new patient client click the New patient button 1 1 In the opened Add patient table 1 2 enter name select for sex and appropriate racial variation of patient s hair Confirm your entry by pressing OK or choose Cancel to exit Next step is to fill out the Outpatient card Click on Outpatient card button 1 3 and fill in all its graphs 2 0 Fig 2 The accuracy and extent of information provided in Outpatient card its Questionnaire part 2 5 primarily affects the objectivity of the Automatic Conclusion module 1 29 Fig 1 Profile picture for patient can be taken by camera 2 2 or downloaded from file 2 3 After entering patient s weight and height data the body mass index BMI 2 4 will be calculated automatically Underweight BMI value will be shown in blue color overweight in red After the Outpatient card data is filled out click to Save 2 6 Cancel 2 7 Print 2 8 checkmark to
94. reated under the Additional studies folder Folder content can be previewed anytime by clicking the Additional studies module button 1 26 Fig 1 NOTE In case when it is necessary to save the image into a file click Save icon 13 6 You may be prompted where to save the overall full name date information or just the information that is set to show in the field of image Select the desired storage capacity and click OK to confirm The image can be also printed out by clicking Print icon 13 7 NOTE By means of Point localization icon 13 10 you can mark up specific measurement points on patient s scalp where the hair counts have been performed You can utilize this information for future reference The steps are identical to paragraph 4 5 Point localization function description above NOTE By means of Marker icon 13 20 you can mark up with different color any image sections which may be important to pay patient s attention to during the diagnostic session Select the desired color marker and circle an area or a subject of interest amp ATTENTION Before proceeding to diagnostic session make sure Scope scaling icon 13 9 settings have been set according to the paragraph 3 3 Scaling settings based on Diagnosis Scope magnification above e 13 2 Phototrichogram analysis The Phototrichogram analysis is based on the same principles as the hair density and diameter calculat
95. richogram Trichogram Dermatoscopy Performed Phototrichograms 2 3 2012 9 04 39 PM Hair calculator 21 0 Summary report EJ Hospital Anxiety and Depression Scale Additional studies Select the components to report v Trichoscopy New py Phetcinehogtet Express Trichoscopy v Tricl Hos Ankiet Outpatie 7 Y Deimatoscopy Conclusions and Recommendations vI Automatic Conclusion 7 v Additional studies x Patient search bf V Hair calculator Automatic Conclusion J 7 vV Conclusions and Recommendations First date x Summary report Last date 4 Set template for report Search Save archive co Performed Conclusions and Recommendations 2012 9 26 53 AM Restore databag X Cancel Select video cq e 21 1 Set template for report function The Set template for report function 1 31 Fig 1 is designated for cases when it is necessary to print out Summary report or any other reports on the specific preset forms with the company or institution name address and other information on it The template file should be a document in the MS Word 97 2003 doc file format If you wish the report content to be printed out within specific area of the template mark this area on template with If no mark up is present the report will be built and attached to the end of the template www TrichoSciencePro com Professional hair and scal
96. roperly adjusted before conducting Trichoscopy 1 20 Phototrichogram 1 21 Trichogram 1 22 Dermatoscopy 1 23 and Express Trichoscopy 1 27 sessions By default Program may be configured to magnifications from x25 to x60 for hair density section of Trichoscopy and Express Trichoscopy sessions as well as Phototrichogram Trichogram and Dermatoscopy sessions The default settings for hair diameter sections of Trichoscopy and Express Trichoscopy sessions may be configured from x100 to x200 magnifications The following agenda describes how to change scaling settings e Left click the Scope scaling icon 3 9 in order to open the Scope scaling window 3 13 In Lens magnification section 3 16 check the proper radio button corresponding to your Diagnosis Scope magnification The Width of the image capture window value 3 14 will be adjusted accordingly Confirm settings by clicking Save button 3 23 Now your equipment is set to conduct diagnostic session If you don t know the magnification of www TrichoSciencePro com Professional hair and scalp diagnostic software ter 3 shoscopy module ITrichoSciencePro equipment used or want to check the validity of claimed magnification perform the setup procedure using standard prototype scale You will need a millimeter scale or a picture with a millimeter scale After clicking the
97. s and much more The module functions in automatic mode by default The data for its upper portion Terminal and Vellus hairs density and percentages in Parietal and Occipital areas percentages of Telogen and Anagen hairs in Parietal and Occipital areas as well as percentages of Vellus Telogen hairs in Parietal and Occipital areas 16 1 is obtained from corresponding Trichoscopy and Phototrichogram sessions Sex 16 2 Age 16 3 and Racial variation of hair 16 4 fields data is obtained from the data contained in Outpatient card Per user discretion all the data above which is being obtained automatically may be modified and corrected anytime by typing new information into applicable fields The bottom module portion contains calculated data in applicable fields 16 7 as follows Total mean and actual quantities of scalp hairs with mean quantity in reference to specific patient s racial hair variation and actual quantity breakdown to Terminal and Vellus hairs counts mean and actual hair growth rates with mean rate in reference to specific patient s racial hair variation and actual rate breakdown to Parietal and Occipital areas total actual hair loss rates with a breakdown to Terminal and Vellus hairs counts The measurement error may reach up to 10 depending on user s qualifications You may Print Download to MS Word Close 16 8 or save results into Summary report 1 30 Fig l by selecting To report check
98. s or additions to the text To make changes place the cursor within text area Click the right mouse button From pop up menu select the desired item to make a correction If wanted to add own information click Add information Choose fields allows to select what information you want to be displayed Reset position is intended to move information into its original location within the image if the image scale was changed or text has moved Select font allows to choose displayed text appearance options d NOTE Results of any operations performed while working with Program are stored by default in the final report If you do not want to save results into report uncheck To report checkbox 4 25 in the lower right corner of the image window and or the charts window 4 28 Even if you choose not to save data into report it does not mean that this data is lost after the session ends All data obtained will be stored if the session itself is saved www TrichoSciencePro com Professional hair and scalp diagnostic software Chapter 4 H ity and diameter d rich S cie nce P ro measurements and calculations Follicular unit counts a a i Occipital area hair density window 1 J ahs iA Ee r aE l Hair density and diameter cha Hair density Hair diameter 330 360 330 300 270 Total hairs 256
99. scretion Print the report and close it You will be prompted to save it before exiting You may also save it as an uneditable PDF file to personal patients folder in Additional Studies folder conveniently accessible from desktop to email it or other uses When finished you can exit by closing the diagnostic session window You will be prompted to save the session If you choose to save it this patient s diagnostic session will be recorded and appear in the Performed Phototrichograms module 1 6 Fig 1 in the form of date and time of the session Any recurring patient sessions will be also recorded and listed in the module if saved Any of these sessions may be reviewed anytime To choose the session of interest right click on the appropriate date so it gets highlighted in blue Depending on what has to be viewed specific diagnostic session itself or generated session report click on the Load session button 1 17 or the Show report button 1 18 respectively NOTE Any performed during diagnostic session actions and their results are stored by default in the final report If some specific data was not included into the report or you wish to include some additional information close the report without saving it Make any changes and open the report again You will be prompted to go to the previously developed report or generate new one If you do not want to generate full report at all or want it to be partial uncheck some or
100. se the left mouse button and scroll the mouse wheel If scrolling forward the line drawn along the hair shaft starts to thicken if scrolling backwards the line will become thinner When the thickness of the line becomes equal to the thickness of the hair shaft click the left mouse button to confirm the proper value of hair thickness measurement Proceed to next hair measurement If working without a mouse wheel use Slider 13 3 located in the upper left corner of each window e 13 7 Density correction function E The proper Phototrichogram assessment requires evaluation of only those hairs which are clearly visible in the field of view Any hair shafts extending beyond the field of view should not be accounted as their lengths are unclear This requirement is essential to properly calculate Anagen and Telogen hair percentages However since during the study hair density counts are carried out simultaneously density measurements have to be corrected as well since it is important to account for all hairs growing within the field of view To do this left click on the Correct density icon 13 17 and measure hair density and diameter for the rest of the hairs in the field of view by the first method described in paragraph 4 1 Hair density and diameter calculations using the first method above 13 8 Follicular unit count mode This method supplements hair density count with hair distribution per follicular units information
101. sional hair and scalp diagnostic one Chapter 6 Hair diameter Tricho SciencePro measurements and calculations O e Chapter 6 Hair diameter measurements and calculations Click on the second Hair diameter button 3 2 Fig 3 and press the Scan icon 6 2 Capture window will open Place the Diagnosis Scope lens optimally with magnification from x100 to x200 on the chosen location of patient s Parietal area Androgen dependent zone and position the mouse cursor within image capture window if a snapshot button on your Scope cannot be used After good quality image is obtained lock it by pressing the left mouse button Click OK and the picture will appear in the left image window designated for Parietal area In the same sequence perform the operation in the right image window to study the second normally Occipital area Androgen independent zone of patient s scalp Scope scaling 6 4 shall be configured in advance in accordance with the applicable Diagnostic Scope magnification for details refer to paragraph 3 3 Scaling settings based on Diagnostic Scope magnification above There are two different ways to calculate diameters of the hair e NOTE Images of the scalp and hair can be also uploaded from file by pressing appropriate icon 6 1 Any files to be uploaded into the program shall be located in the Additional studies folder created on the desktop during installation For convenience of the patient s
102. sity calculations in the added window s allow to significantly increase the reliability of the measurements performed All the results of hair density and diameter calculations obtained from charts and reports for a given Parietal or Occipital area can be calculated as the mean arithmetic value of all the measurements performed To obtain mean arithmetic value of all measurements in several windows added click Mean arithmetic value icon 4 11 www TrichoSciencePro com icho SciencePro measurements and calculations Follicular unit counts 2 f Professional hair and scalp diagnostic software Chapter 4 Hair density and diameter a e 4 9 Hair length function d Hair length icon 4 7 allows to perform linear length measurements of any growing hair within the site To do this place the cursor on the base of the hair press and hold down either mouse button move the cursor along the shaft to the hair tip and release the button The actual value of hair length will be displayed in the top right corner of the image window Once the mouse button is released and the hair length is set the actual measured hair length value in millimeters will pop up on the screen by the measurement site To cancel the performed measurement quickly click once on either mouse button For the performed measurements accuracy always make sure Scope scaling function 4 17 is properly configured in accordance with the applicable Diagnos
103. te the mouse wheel either direction to get the width of the color strip to be equal to hair thickness Press on left button again to complete measurement Proceed to next hair evaluation Some hairs in the field of view may not get detected at all like very thin or light shaded hairs and hairs which get attached side by side to neighboring hairs Press on Manual detection mode 13 15 and Diameter auto measurement mode 13 16 buttons As this correction method is actually same to the third method with manual detection and diameter auto measurement mode for the complete instructions refer to its full description below in paragraph 13 5 e NOTE In case when correction of certain performed measurement is not helpful and it is more convenient to make a new measurement instead use Cancel 13 37 function to take one or more steps back to correct measurements in error or Clear field 13 26 function for groups of hairs in one area or Clear 13 25 function to completely remove all previously performed actions within given field of view Same applies to correct any errors with Program a ATTENTION Only clearly visible by entire length hairs in given field of view have to be evaluated with Phototrichogram study as their lengths are unclear Although those hairs which are growing out of the given field of view will be in addition examined for proper density assessment see paragraph 13 7 Density correction function
104. thickness of the line becomes equal to the thickness of the hair shaft click the left mouse button to confirm the proper value of hair thickness measurement Proceed to the next hair measurement NOTE If working without a mouse perform mouse wheel operations described above using Slider 4 13 located in the upper left corner of each window www TrichoSciencePro com icho SciencePro measurements and calculations Follicular unit counts e f Professional hair and scalp diagnostic software Chapter 4 Hair density and diameter a ATTENTION The automatic determination of hair diameter may not work properly in cases when hairs are too light contrasted poorly in relation to surrounding tissues hairs grow too close to each other in bunches image taken is not sharp Scope s resolution is too low etc e 4 3 Hair density measurements and calculations using third method This method is mostly used when measuring only hair density leaving their diameter measurements for next Trichoscopy session Hair diameter section 7 00 Fig 7 Click on Manual detection mode icon 4 2 and release Diameter auto measurement mode icon 4 3 to disable this function Place the cursor closer to the base of the hair press and hold down mouse button and just move the cursor slightly along the shaft Use the left mouse button for Terminal hairs and the right mouse button for Vellus hairs The length of the lin
105. tic Scope magnification for details refer to paragraph 3 3 Scaling settings based on Diagnostic Scope magnification above e 4 10 Marker function e Marker icon 4 6 allows to choose and mark up with different color markers any image sections or details which may be important to pay patient s attention during the diagnostic session Select the desired color marker and circle an area or a subject of interest 4 11 Information function For detailed information on the measurements performed within the image field of view click Information icon 4 12 The absolute number of measured hairs density per sq cm total amount of Terminal and Vellus hairs hair diameters thick medium and thin Terminal hair ratios degree of Anisotrichosis all this data will appear within image field If several measurement windows have been used click Mean arithmetic value icon 4 11 to obtain mean arithmetic value of all the measurements performed NOTE In wanted to save the image into a separate picture file click Save icon 4 14 You will be prompted where to save the overall full name date information or just the information that is set to show in the field of image Select the desired storage capacity and click OK to confirm The image can be also printed out by clicking Print icon 4 15 J NOTE The information of the performed counts may be edited amount of information provided font change
106. tically coinciding with the thickness of hair If the automatic measurement is performed correctly confirm the completion of the measurement by clicking the left mouse button and proceed to the next hair measurement If the automatic measurement was carried out incorrectly e g drawn line does not thicken goes beyond the diameter of the hair or vice versa continue to measure hair diameter manually To do this release the left mouse button and scroll the mouse wheel the line drawn along the hair shaft starts to thicken if scrolled backwards the line will become thinner When the thickness of the line becomes equal to the thickness of the hair shaft click the left mouse button to confirm the proper value of hair thickness measurement Proceed to the next hair www TrichoSciencePro com zs Professional hair and scalp diagnostic i Chapter 6 Hair diameter Tricho SciencePro measurements and calculations O If working without a mouse perform mouse wheel operations described above using Slider 6 6 located in the upper left corner of each window NOTE The semiautomatic detection mode and diameter auto measurement mode may not work properly in cases when hairs are too light contrasted poorly in relation to surrounding tissues image taken is not sharp hair grow too close to each other in bunches etc In such cases to avoid any errors the program function of automatic measurement is being disabled by default s NOTE
107. time typically 48 to 72 hours the Anagen hairs will grow out while the Telogen hairs will be remaining of the same length In order to calculate the hair growth rate properly an exact number of hours that passed from the moment of trimming to the new image acquirement shall be entered into the Time period between measurements hours window 13 40 before the hair growth rate calculation is carried out The value displayed by default in this window is 48 hours The result of the hair growth calculation will be reflected in the Conclusion Print results section 13 2 www TrichoSciencePro com f Professional hair and scalp diagnostic software Chapter Ia Phototrichogram TTICNOSCI Pro l Ga lrichosciencePro module e 13 13 Anagen Telogen hair diameter threshold function E Anagen and Telogen hair percentage and ratio calculations are based on the difference in length between Anagen hairs which grew out and Telogen hairs which remained the same within a set period of time For proper calculations it is necessary to enter the correct hair length for the Threshold for Anagen Telogen hair length mm value 13 41 To correctly determine the length locate the longest Telogen hair in the field of view and trace its entire length by holding down the left mouse button Watch for the hair length value in mm that appears in the yellow window in the upper right corner of the image Enter this number into the Thres
108. uation will open Press the Detailed report button 17 4 if you want to get all complete test data The Detailed report window 17 5 will open You may Print Download to MS Word Close 17 6 or save results into Summary report 1 30 Fig 1 by selecting To report checkbox 17 7 in the lower right corner of the window I TrichoSciencePro v1 1SE Patient s name Performed Trichoscopies Patient name Date 2 3 2012 8 25 40 PM Trichoscopy Bob Johnson 2 4 2012 10 31 15 AM Mary Smyth 2 4 2012 9 26 53 AM Phototrichogram CP Hospital Anxiety and Depression Scale Patient Mary Smyth Trichogram Dermatoscopy Hospital Anxiety and Depression Slale Hair calculator Hospital Anxiety and Depression Scale Definitely as much X Automatic Conclusion Patient Mary Smyth Yes but not too badly x 1 feel tense or wound up Most of the time 2 still enjoy the things used to enjoy 3 get a sort of frightened feeling as if something awful is about to happen Subclinical depression Clinical anxiety Detailed report 4 can laugh and see the funny side of things Not quite so much now X 5 Worrying thoughts go through my mind A lot of the time Close 6 feel cheerful Not often F Detailed report Patient Mary Smyth 7 can sit at
109. up of 7 icons provides functionality to mark up Anagen Dysplastic Anagen Broken Anagen Anagen with Papilla as well as Catagen Telogen and Dystrophic hairs In the window s bottom scrollable area representing diagnostic Sample database 14 20 you can locate various epilated hair root reference images By placing mouse cursor over each of these images you will have their names displayed You may also place the cursor on the selected image and double click the left mouse button to open the selected image in a separate window with its name displayed In case of ane mistake made use Cancel icon 14 10 to correct it With each additional click it will take you back by sequentially reverting to previously performed step After completing the counting process press Trichogram table icon 14 17 to open the table with results 14 25 for review NOTE In order to add new diagnostic images to the Sample database 14 20 place mouse cursor over the image and right click with the mouse You will be prompted to Add image to Own Base Left click on it in order to open the Sample card 14 21 Type the name of diagnosis in the Sample title field 14 22 and click Save 14 24 The image will appear at the very end of the scrollable area More images can be uploaded by clicking Select image button 14 23 If necessary images from the Sample database 14 20 may be edited To do this place mouse c
110. ursor over any image in it and right click From the menu select an option to open add delete change or move the selected image NOTE Diagnostic images can be also downloaded from file by pressing appropriate icon 14 11 Any image files to be loaded into program have to be located in the Additional studies folder that was created on the desktop during installation For convenient additional data management for every new patient entered into program a personal subfolder is created under this Additional studies desktop folder Folder content can be previewed anytime by clicking Additional studies module button 1 26 Fig 1 NOTE In case when it is necessary to save an image into a separate file click Save icon 14 13 The image can also be printed by clicking the Print icon 14 14 hoSciencePro cora f Professional hair and scalp diagnostic software Chapter 14 Trichogram TTICNOSCI Pro l Gaz LrichosciencePro module NOTE By means of Marker icon 14 4 you can choose and mark up with different colors any image sections which may be important to pay patient s attention to during the diagnostic session Select the desired color marker and circle an area or a subject of interest Any mark ups on the image can be deleted by using Clear icon 14 5 2 NOTE The Information icon 14 6 allows placing any important information within image field by right clicking Add informati
111. utton 1 18 respectively NOTE Any operations performed while working with the program results are stored by default in the final report If some specific data was not included into the report or you wish www TrichoSciencePro com Professional hair and scalp diagnostic software HESON ween pter 14 Trichogram module to include additional information close the report without saving it Make any changes and open the report again you will be prompted to go to the previously generated report or build new one If you do not want to save results into report uncheck To report checkbox 14 19 Even if you choose not to save data into the report it does not mean that this data is lost after the session ends All the data obtained will be stored if the session itself is saved If after diagnostic session completion the report per this session results was generated and saved it will show in Performed Trichograms module 1 7 in form of sign after date and time of the session and the Show report button 1 18 will be enabled N 20 1 gfe Ibex 90 gt BREE p ann Ey 14 19 gt x Epilated 14 23 pg eine Trichogram 1 hair type Anagen JP Displastic Anagen X Cancel Broken Anagen Anagen with papilla Telogen Catagen Dystrophic Sum Absolute amount 9 38
112. will be set to one of the three preset values 30 35 or 40um 13 45 This function changes dynamically e g if the field of view mostly contains thick Terminal hairs the threshold will be automatically set to the value of 40 microns if the hairs are mostly fine the threshold will be set to 30 microns if hairs are mixed the threshold will be set to 35 microns In case if you want to change the threshold you have to turn automatic detection off To do this right click on the red link Threshold for Terminal Vellus hair um 13 44 at the bottom of the window In the pop up window uncheck the Automatic threshold determination checkbox The text color of the link will change to black Enter the desired threshold value into the Threshold for Terminal Vellus hair um window 13 45 If the threshold has to be reset to automatic mode again right click on the Threshold for Terminal Vellus hair pm link 13 44 and check the Automatic threshold determination checkbox in the pop up window The text color of the link will change back to red thus indicating that threshold determination is configured automatically again NOTE The threshold data above is corresponding to average European Caucasian hair characteristics For ethnic variations of hair automatic thresholds will be set accordingly with selection in the Add patient table 1 2 Fig 1 www TrichoSciencePro com f Professional hair and scalp diagnostic

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