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        KDS35 Small Animal Ventilator
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1.   option  KD Scientific will repair or replace the unit if it is found to be defective as to work   manship or material     This warranty does not extend to damage resulting from misuse  neglect or abuse  normal  wear and tear  or accident  This warranty extends only to the original customer purchaser     IN NO EVENT SHALL KD SCIENTIFIC BE LIABLE FOR INCIDENTAL OR CONSEQUEN   TIAL DAMAGES  Some states do not allow exclusion or limitation of incidental or conse   quential damages so the above limitation or exclusion may not apply to you     THERE ARE NO IMPLIED WARRANTIES OF MERCHANTABILITY  OR FITNESS FOR A  PARTICULAR USE  OR OF ANY OTHER NATURE  Some states do not allow this limitation    on an implied warranty  so the above limitation may not apply to you     If a defect arises within the one year warranty period  promptly contact your local distributor  or KD Scientific  84 October Hill Road Holliston  Massachusetts 01746 1388  508 429 6809  Goods will not be accepted for return unless an RMA  returned materials  authorization  number has been issued by our customer service department  The customer is  responsible for shipping charges  Please allow a reasonable period of time for completion of  repairs  replacement and return  If the unit is replaced  the replacement unit is covered only  for the remainder of the original warranty period dating from the purchase of the original  device        This warranty gives you specific rights  and you may also have other rights whic
2.  30 0 ml breath  30 CC   The smaller cylinder is factory  installed  and the larger one is supplied separately  The mechanical design features a linkage  that enables the piston to touch the end of the cylinder at each stroke regardless of the  volume  This assures that all the air gas mixture taken into the ventilator is expelled   at each stroke     A positive mechanical slide valve is actuated by a cam on the motor to synchronize inspira   tion and expiration with the motion of the piston  Any NON EXPLOSIVE gas air mixture can  be used with the ventilator  Connection kit  78 0937  is suggested for this connection  A  three way slide valve is attached to the mechanism plate at the end of the cylinder and actu   ated by a cam on the motor     This ventilator CANNOT BE USED IN AN EXPLOSIVE ATMOSPHERE OR WITH ANY EXPLO   SIVE GASES SUCH AS ETHER OR CYCLOPROPANE  ETC  THESE VENTILATORS ARE NOT  EXPLOSION PROOF     KDS35 Small Animal Ventilator    Voltage Selection    1  The    KDS35    Ventilator is equipped with a 115 230V selector feature  which is  incorporated into the power entry module located on the side of the unit  see  figure below   The Ventilator is shipped from the factory with the voltage selector  set at 115V  To change voltage from 115V to 230V  follow these steps    a  Turn off main power  and disconnect power cord   b  Using a small flathead screwdriver  pry open the fuse access door on the  power entry module  see figure below    c  Remove fuse holder by usin
3.  the disconnecting device     Observe all Terminal Ratings  Review the operating manual to learn the ratings on all connections     Use Proper Fuse  Use only specified fuses with product     Avoid Exposed Circuitry  Do not touch any electronic circuitry inside of the product     Do Not Operate with Suspected Failures  If damage is suspected on or to the product do not operate the product  Contact qualified  service personnel to perform inspection     Place Product in Proper Environment  Review the operating manual for guidelines for proper operating environments     Observe all Warning Labels on Product  Read all labels on product to ensure proper usage     CAUTION Protective Ground  Refer to Manual Terminal    KDS35 Small Animal Ventilator    Description  amp  Features    The KDS35 is a volume controlled small animal rodent respirator     e Strong motor and motor speed control with LED  light emitting diode  read out of rate   stroke rate or breaths min      e Vertical slide valve that has no    O    Rings or passive check valves and requires no  adjustments     e Orientation allows for minimal system dead space and thus more precise tidal  volume delivery to the animal    The KDS35 is a positive volume ventilator intended to meet the respiratory requirements of  small laboratory animals weighing up to 5 kg  11 Ib   covering rodents through rabbits     This ventilator is furnished with two interchangeable piston cylinder assemblies of 0 2 to   5 0 ml breath  5 CC  and 1 5 to
4.  the water surface will give the PEEP pressure in  cmH20     KDS35 Small Animal Ventilator    Cleaning  amp  Maintenance    CLEAN    ING    To clean the exterior surfaces  use a lintfree cloth to remove loose dust  Use care to avoid    scratchi    ng the clear display window  For more efficient cleaning  use a soft cloth dampened    with water or an aqueous solution of 75  isopropyl alcohol     MAINTENANCE    No spe    cial maintenance is required other than periodic lubrication of the piston O rings and    the slide valve with the special non toxic grease provided  To get to the slide valve for lubri     cation   1   2   3   4     5     Remove the four screws holding the valve to the 1 4  aluminum black back plate   Remove the screws in front that hold the cylinder and valve together    Lift entire valve assembly up and out of Ventilator    Pull stainless steel valve rod free of valve block     Lubricate sparingly     KDS35 RODENT VENTILATOR REPLACEMENT PARTS          co    CYLINDER  VALVE BLOCK 5 cc 0683 033  ASSEMBLY 30 cc 0683 034  0683 007    PISTON        2  O RING  a  gt   503 0680 018  5 cc 5013 019       30 cc 0681 011 a6 coeur One   lt o on ae                   LZ                                              O RING   2  SCREWS 5013 017   4 40 x 1 1 8 HELICAL PISTON SHAFT  5101 165 COUPLING    5108 026    LUBRICATION  This KDS35 Ventilator is shipped with the appropriate grease to lubricate the piston and O     rings in    the cylinders and the inside of the slide va
5. 8 0391  78 0395    78 0396    78 0397    Adjustable from 30 to 150 strokes min while the  ventilator is running    1 1 fixed   25 x 32 5 x 20 cm   10 x 13 x 8 in   9 5 kg  21bs     100 120 VAC 200 230 VAC  0 7A 0 35A max    50 60 Hz    Continuously variable from 30 to 150 strokes min   while the ventilator is running  with    LIGHT EMITTING DIODE  LED  DISPLAY     Adjustable from 0 2 to 5 0 cc stroke or 1 5 to  30 0 cc stroke while the ventilator is running    0  C to 40  C  32  F to 104  F   20  to 80  RH  non condensing  II   1    5121 074    128   3 25mm   188   4 78mm     78 0391    Small Animal Volume Controlled Ventilator    Overhaul Kit for 5cc Small Animal Ventilator   contains O rings  valve springs  lubricants  etc  to  overhaul Ventilator    Overhaul Kit for 30cc Small Animal Ventilator   contains O rings  valve springs  lubricants  etc  to  overhaul Ventilator    Connection Kit    KDS35 Small Animal Ventilator    General Information   Warranty and Repairs    SERIAL NUMBER  All inquires concerning our product should refer to the serial number of the unit  Serial num   bers are located on the rear of the chassis     CALIBRATION   All syringe pumps are designed and manufactured to meet their performance specifications  at all rated voltages and frequencies  A calibration certificate is available upon request   Contact customer service for details and pricing     WARRANTY   KD Scientific warranties this instrument for a period of one year from date of purchase  At its
6. Product with Municipal Waste      Special Collection Disposal Required       KDS35 Small Animal Ventilator    Contents  Specification s s  ssi sa cthses n R in oer Aa a A arcane 2  Parts atid Accessories  ics scissasesssatadssasressuasesdsesyusesessduusssuvseaa  EAE TERE 2  General Information   Warranty and Repairs         esscssscsseessesessseesssneesssneesssneeessneessness 3  General Safety Summary ssiri ani aia 4  Description and  Features yesan otin a EEE eaters i 5    Voltage Selection            Fuse Replacement    Pump Operation     Conriecting Animal scisccscsssccosccisscvaasusceccdssstussnscocesteasnesticcivessvuansssetessdannvennedesesboceeisn 7  Selecting Rate  amp  Volumes is celes shail suedidishnuiiiendionniteananeaes 8  Setting  Volume  amp  Ratei asrori E E a need inranncanne ohana  9  Use of Gas MixtUte a saa r aa E ET E AEOS 9  Creating PEEP insirri nn a ea AE EEIN ERA 9  Cleaning Maintenance esiin enasi a 10  Changing  Pistort eC yim dettisisiasstsss ccccdissjavssptoalesiaeelvcheiasasivesdswstiavssuesuvh seiuasnsbosseuscaubonnn ates 11  R   pair Kit secedesssorsvenes ctosemneeearaunonononasnmar nam mvanaanmuvennenamminnsnsinrieetemem Tete  11    KDS35 Small Animal Ventilator    Specifications    Rate    Phase Ratio  Dimensions   HxLxW  Weight    Power    Stroke Rate    Volume    Environmental   Operating Temperature  Operating Humidity  Installation Category  Pollution Degree   Port   Part Number    Size  ID  OD    Catalog No     Parts and Accessories    7
7. Run Ventilator at lowest speed and stop when the helical coupling is exposed     Using a 0 050 Allen wrench  provided   disconnect the white piston from the cou   pling  leaving the coupling on the piston shaft     Remove the two screws located in the front of the slide valve   Remove piston and cylinder   Be careful to save the O ring that is recessed in the slide valve block between the    screws  The O ring provides the airtight seal between the plastic cylinder and the  valve block     TO INSTALL THE PISTON AND CYLINDER    1   2     3     4     5     6     7     Pick out the new piston and cylinder   Using pliers  remove the piston and lubricate with the grease provided     Insert the lubricated piston in the cylinder so that the rear of the piston is flush with  the rear of the cylinder with the 1 8  diameter coupling stud protruding     Fasten the cylinder to the valve block with the two screws  making sure the O ring  is in place  Do not tighten these two screws completely  but just enough to hold  the cylinder in place     The object of alignment is to have the stud at the end of the piston be exactly in  line with its mating hole in the helical coupling  This insures that the piston moves  freely within the cylinder without undue friction     The two screws at the front of the valve block control left to right alignment while  the four screws at the rear of the slide valve control up and down alignment  By  adjustment of these 6 screws the proper alignment can be mad
8. at  expired air can be collected or recycled     e The middle port is the room air gas channel to the animal     e The bottom port  closest to the chassis in new orientation  is the room air or gas  mixture intake     NOTE  It is important that the tubes to and from the animal be as short as possible  The new  orientation allows the animal to be as close as possible to the Ventilator for minimal dead  space in the system     The actual connection to the animal can be either    e Tracheal cannula with y adapter   e Intubation cannula with y adapter  A selection of trachael cannula and endotracheal tubes are listed in the KD Scientific  Catalog and on our website www kdscientific com  It is important that the volume of tubing    shared by inspired and expired air  dead space  be kept to a minimum by having the    Y    or     T    connector as close to the animal as possible     E  X          Y    Connector   close to animal  From Animal ANIMAL    aaa   gt   gt  fae    P Expired Air    EXHAUST                      Tracheal  Cannula  or  Endotracheal    Tube TO ANIMAL    To Animal    OUT ae age page eee zee     i opps x t ra  Air Gas Input a      IN t    mae Eeee n m L a      gt  Esso Cylinder  amp  Piston    ROOM AIR    CE     eae tee                                                                 KDS35 Small Animal Ventilator    Pump Operation   continued     SELECTION OF RATE AND VOLUME   Refer to the Ventilator Graph  below  to select the appropriate tidal volume and respirat
9. e  Remember that  the screws interact with one another so the procedure may have to be repeated  one or more times     When proper alignment is achieved  the helical coupling should be connected  If  alignment is correct  the coupling should slide onto the piston stud without bending  of the piston rod     KDS35 Small Animal Ventilator    Repair Kit    REPAIR INSTRUCTIONS FOR THE KDS35 RESPIRATOR        VALVE BLOCK  HT O RING  5013 051                         Ao a             O RING  5013 019    kd Scientific    Declaration of Conformity    Manufacturer     KD Scientific  Inc    84 October Hill Rd    Holliston  MA 01746 1388 U S A   Phone   508  429 6809    We herewith declare that the following product     Product Name     Model Numbers     KDS35 Small Animal Ventilator  78 0391    To which this declaration relates  is in conformity with the applicable EC  Directives  harmonized standards  and other normative requirements     Application of  Council Directive s      Standard s  to which  Conformity is Declared     Safety     Emissions Immunity     Signature     73 23 EEC  89 336 EEC    EN 61010 1  2    Edition  2001     EN 61326 1997 w  A1 1998  EN 61000 4 2 1995   EN 61000 4 3  1996   EN 61000 4 4 1995   EN 61000 4 5 1995   EN 61000 4 6 1996   EN 61000 4 11 1994   EN 61000 3 2 2000 w  A 14  EN 61000 3 3 1997    Date  8 1 06    Beth Bauman  V P  of Operations       
10. g the small flathead screwdriver   d  Rotate the red fuse holder 180 deg  and install back into power entry  module   e  Close small access door firmly until fully closed  In power entry module win   dow  see detail below  230V should be seen   f  Reinstall power cord   2  Turn on main power switch located on the rear panel  The display will now illumi   nate  The number displayed is the current strokes per minute rate     Fuse Replacement    Key Information    1  Make sure power cord is disconnected from the main power supply before servic   ing the fuse   2  Use only Type 3AG  1 4    x 1 1 4     0 75 amp  250 volts  Type T  time delay   fuses  KD Scientific part   5153 554 or equivalent    Turn off power and remove power cord from power module  Use a straight blade screwdriv   er to pry open the access door  Remove the fuse holder and then remove the fuses from this    holder as shown in the figure below  Replace fuses using only 0 75A amp  250 volts  Type T  fuses  Then replace the fuse holder     Screw Driver m                          o ra    g Fuse  T a  0 g 0                                                          Front View Side View Fuse Holder Detail    KDS35 Small Animal Ventilator    Pump Operation     CONNECTION TO THE ANIMAL    The vertical slide valve has four ports  see figure below      e The top port  furthest from the chassis in new orientation  is the return channel from  the animal  which leaves the Pump at the port on the side  It is at this top port th
11. h vary from  state to state     REPAIR FACILITIES AND PARTS   KD Scientific stocks replacement and repair parts  When  ordering  please describe parts as completely as  possible  preferably using our part numbers  If practical   enclose a sample or drawing  We offer a complete  reconditioning service     CAUTION  This pump is not registered with the FDA and is not for clinical use on human or veterinary  patients  It is intended for research use only     KDS35 Small Animal Ventilator    General Safety Summary    Please read the following safety precautions to ensure proper use of your syringe pump  To  avoid potential hazards and product damage  use this product only as instructed in this man   ual  If the equipment is used in a manner not specified by the manufacturer  the protection  provided by the equipment may be impaired     TO PREVENT HAZARD OR INJURY     Use Proper Line Cord  Use only the line cord shipped with the product and make sure line cord is certified for coun   try of use     Ground the Product   This product is grounded through the grounding conductor of the power cord  To avoid elec   tric shock  the grounding conductor must be connected to earth ground  Before making any   connections to the input or output terminals of the product  ensure that the product is properly  grounded     Make Proper Connections  Make sure all connections are made properly and securely     Orient Equipment Properly  Do not position the equipment such that it is difficult to reach
12. ion  rate as a function of animal body weight  As a rough guide an adult rat will weigh between  200 and 500 grams with tidal volumes between 0 6 to 1 25 cm3 with respiration rates  between 66 to 210 breaths min  The average rate is 100 breaths min  For most rodents the  5 cc cylinder will be adequate  For larger animals it will be necessary to change the cylinder                                                                                                                                                                                                                                                     70 100 200 300 400 600 800 1 2 3 4 56 8 10 15 20 30 40  500 500  400 400  300 300  200 200  150 150     o 100 100    80 80      oO 60 60  Qa 50 Breaths per Minute  10 50  E 40 40 40       30 30  5 15  D 2 S a  20     15 15  Fa 25  E 10 60 10  8 30    70 8     6 80 6  5    5 90  o   gt  4 4  m 100     3 3      B 2 2  40  1 1  0 8 0 8  0 6 0 6  0 5 0 5  0 4 0 4  70 100 200 300 400 600 800 1 2 3 4 56 8 10 15 20 30 40     Grams  Animal Body Weight  Kilograms     Ventilator Graph  Tidal Volume vs  Weight  amp  Rate for Laboratory Mammals in Resting State    Apparatus dead space must be added     KDS35 Small Animal Ventilator    Pump Operation   continued     SETTING VOLUME   The volume delivered is read by observing the excursion of the O ring  on the piston  which is  closest to the valve block  This piston O ring excursion is relative to the volume scale on the  outside of the cy
13. kd Scientific  KDS35 Small Animal    Ventilator  User   s Manual    Publication 5614 001 REV A    WEEE RoHS Compliance Statement    EU Directives WEEE and RoHS    To Our Valued Customers     We are committed to being a good corporate citizen  As part of that commitment   we strive to maintain an environmentally conscious manufacturing operation  The  European Union  EU  has enacted two Directives  the first on product recycling   Waste Electrical and Electronic Equipment  WEEE  and the second limiting the use  of certain substances  Restriction on the use of Hazardous Substances  RoHS    Over time  these Directives will be implemented in the national laws of each EU  Member State     Once the final national regulations have been put into place  recycling will be offered  for our products which are within the scope of the WEEE Directive  Products falling  under the scope of the WEEE Directive available for sale after August 13  2005 will  be identified with a    wheelie bin    symbol     Two Categories of products covered by the WEEE Directive are currently exempt  from the RoHS Directive   Category 8  medical devices  with the exception of  implanted or infected products  and Category 9  monitoring and control instruments   Most of our products fall into either Category 8 or 9 and are currently exempt from  the RoHS Directive  We will continue to monitor the application of the RoHS  Directive to its products and will comply with any changes as they apply       Do Not Dispose 
14. linder wall  Volume change is accomplished while the Ventilator is running by  turning    volume    knob in the desired direction     SETTING RATE  Adjust the    Rate    control until the desired rate appears on the LED display  Avoid running the  Ventilator at rates exceeding 150 breaths min for periods in excess of 2 hours     CAUTION   DO NOT OVER INFLATE THE ANIMAL  A GOOD RULE OF THUMB IS TO  OBSERVE THE DEPTH OF RESPIRATION IN THE NORMAL CALM UNANESTHETIZED  ANIMAL AND ADJUST THE VOLUME TO APPROXIMATE THIS RESPIRATION DEPTH  WHEN THE ANIMAL IS ATTACHED TO THE VENTILATOR     USE OF GAS MIXTURE   It is possible to introduce non explosive air gas mixtures into the lower room air port   However  the source of gas mixture is usually from a tank delivering gas is at a constant rate  while the Ventilator takes in air gas intermittently  Some sort of buffer expansion chamber  must be provided between the tank and the Ventilator  KD Scientific offers a connection kit   73 0397  to depressurize the gas prior to entering the ventilator  This Ventilator is not  designed to take air gas inputs under pressure     CREATING A POSITIVE END EXPIRATORY PRESSURE  PEEP    To create a PEEP pressure when using the ventilator  simply connect a length of tubing to the     Exhaust    port and submerge the other end in a column of water  There are two locations in  which the clip and cylinder can be installed   depending on the chosen orientation  The depth  of the end of the tubing  in cm  below
15. lve     10    KDS35 Small Animal Ventilator    Changing Piston and Cylinder    This Ventilator is furnished with a 5 cc piston and cylinder installed  A 30 cc cylinder and  piston is also supplied for users that require larger tidal volumes     NOTE  It is extremely important when changing piston and cylinders that they be aligned to  be concentric and in line with the piston shaft     The cylinder is fastened to the 4 port vertical slide valve by means of two screws located  between the    room air inlet    port and the    to animal    port on the front of the slide valve     For ease of mounting  there is an alignment bracket located below the valve body  When re   attaching a valve to the KDS35 Ventilator  the cutout in the valve should sit square and par   allel with the corner of the alignment bracket  This should ensure that the valve and piston  shaft are in line with each other     The vertical slide valve is fastened to the black 1 4  aluminum sub base by four screws locat   ed on the opposite side from the printed label  After mounting a valve  if coupling does not  engage piston shaft  loosen cylinder mounting screws and adjust cylinder position until piston  shaft enters coupling with ease         ALIGNMENT BRACKET    VALVE  MOUNTING  SCREWS    CYLINDER  MOUNTING    SCREWS    11    KDS35 Small Animal Ventilator    Changing Piston and Cylinder  continued     TO REMOVE THE CYLINDER AND PISTON    1   2     3     4   5     6     Set the Ventilator volume to maximum   
    
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